Thomas Agbaedeng

Dr Thomas Agbaedeng

Postdoctoral Research Fellow

Adelaide Medical School

Faculty of Health and Medical Sciences


Dr Thomas A. Agbaedeng is a Research and FHMS Emerging Leaders Fellow at The University of Adelaide with interest in mechanisms driving cardiometabolic disease. At the preclinical level, Dr Agbaedeng investigates pathophysiologic cardiac remodelling using trans-omics approaches, in vitro and in vivo techniques, and computational tools. With these, Dr Agbaedeng believes we could better probe the genesis of cardiometabolic disorders, including pro-arrhythmic substrates, heart failure, atherosclerosis, and cardioembolism. At the clinical level, Dr Agbaedeng is developing pipelines for cardiovascular risk prediction using novel biomarkers, such as genetic variants, adipocytokines, cardiac molecular markers, and fibrotic and inflammatory cytokines.

Thomas Agbaedeng completed his PhD studies at the Centre for Heart Rhythm Disorders, The University of Adelaide. Using multimodal approach of meta-analysis and pre-clinical experimental models, his PhD research has provided many insightful findings on the risks and mechanisms of atrial fibrillation and sudden cardiac death in obesity. His PhD work has been presented for several Young Investigator Awards, including winning 1st Prize in the Young Investigator Award competition at the European Heart Rhythm Association Congress, Barcelona. His impressive PhD research has also been presented at major international conferences and awarded several prestigious accolades. Recently, Dr Agbaedeng was awarded the Achievement Award for the overall top winner of the CSANZ Travelling Grant to the European Society of Cardiology at the ESC Congress in Paris August/September 2019.

As a mentor and teacher, Dr Agbaedeng have supervised several honours (as a principal supervisor [one awarded scholarship for 2020-2021]) and Higher-degree by research students. He has commissioned and led several international collaborative projects, resulting in several high-impact publications. He has authored and co-authored over 15 peer-reviewed publications, 40 conference papers and proceedings, and peer-reviewed 115 manuscripts for high-impact journals (Q1), such as Circulation; Canadian Cardiovascular Journal; Heart Rhythm; Laboratory Investigations (Springer Nature Groups); and American Journal of Physiology. Dr Agbaedeng has served on the committee of several scientific societies, including as a Founding Member and Media Liaison for ISHR Australasia Early Career Investigator committee section.

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  • Appointments

    Date Position Institution name
    2019 Postdoctoral Research Fellow The University of Adelaide
    2019 State Scientific Meeting Subcommittee & Media Liaison Australian Society for Medical Research
  • Awards and Achievements

    Date Type Title Institution Name Country Amount
    2019 Award Young Investigator Award Asia Pacific Heart Rhythm Society Thailand
    2019 Research Award Faculty of Health and Medical Sciences Research Travel Award The University of Adelaide Australia
    2019 Achievement Achievement Award 2019 European Society of Cardiology France
    2019 Award ISHR Student Investigator Award Finalist International Society for Heart Research Australia
    2018 Award National Scientific Meeting Travel Award International Society for Heart Research Australia
    2018 Achievement Medical Staff Society Research Prize Royal Adelaide Hospital Australia
    2018 Award 1st Prize, Young Investigator Award European Heart Rhythm Association Spain
    2018 Award EHRA Congress Travel Award European Heart Rhythm Association Spain
    2017 Achievement Best Abstract Presentation Australian Society for Medical Research Australia
    2017 Award Ralph Reader Young Investigator Award Cardiac Society of Australia and New Zealand Australia
    2017 Award Young Investigator Award Heart Rhythm Society | Cardiac Electrophysiological Society United States
    2017 Award Adelaide Medical School Overseas Research Travel Award The University of Adelaide Australia
    2015 Award Peter M. Steele Electrophysiology Scholarship The University of Adelaide Australia
    2015 Award Adelaide Tuition Fee Scholarship The University of Adelaide Australia
    2011 Award Rivers State Sustainability Development Agency Undergraduate Scholarship Rivers State Government, Nigeria United Kingdom
    2010 Award Rivers State Sustainability Development Agency College Scholarship Rivers State Government, Nigeria United Kingdom
  • Language Competencies

    Language Competency
    English Can read, write, speak, understand spoken and peer review
  • Education

    Date Institution name Country Title
    2020 - 2020 Academic Medical Center Netherlands PostDoc
    2015 - 2019 University of Adelaide, Adelaide Australia Ph.D.
    2011 - 2014 University of Brighton, Brighton United Kingdom B.Sc. (Hons.)
  • Research Interests

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  • Journals

    Year Citation
    2021 Mishima, R. S., Verdicchio, C. V., Noubiap, J. J., Ariyaratnam, J. P., Gallagher, C., Jones, D., . . . Elliott, A. D. (2021). Self-reported Physical Activity and Atrial Fibrillation Risk: A Systematic Review and Meta-analysis. Heart Rhythm, 18(4), 520-528.
    DOI Scopus1 WoS1 Europe PMC1
    2021 Noubiap, J. J., Agbaedeng, T. A., Kamtchum-Tatuene, J., Fitzgerald, J. L., Middeldorp, M. E., Kleinig, T., & Sanders, P. (2021). Rhythm monitoring strategies for atrial fibrillation detection in patients with cryptogenic stroke: A systematic review and meta-analysis. IJC Heart and Vasculature, 34, 1-8.
    DOI
    2021 Noubiap Nzeale, J. J., Agbaedeng, T. A., Ndoadoumgue, A. L., Nyaga, U. F., & Kengne, A. P. (2021). Atrial thrombus detection on transoesophageal echocardiography in patients with atrial fibrillation undergoing cardioversion or catheter ablation: A pooled analysis of rates and predictors. Journal of Cardiovascular Electrophysiology, 32(8), 2179-2188.
    DOI
    2021 Agbaedeng, T. A., Noubiap, J. J., Mofo Mato, E. P., Chew, D. P., Figtree, G. A., Said, M. A., & van der Harst, P. (2021). Polygenic risk score and coronary artery disease: A meta-analysis of 979,286 participant data. Atherosclerosis, 333, 48-55.
    DOI
    2021 Gawałko, M., Agbaedeng, T. A., Saljic, A., Müller, D. N., Wilck, N., Schnabel, R., . . . Linz, D. (2021). Gut microbiota, dysbiosis and atrial fibrillation. Arrhythmogenic mechanisms and potential clinical implications.. Cardiovascular research.
    DOI
    2020 Ellison-Hughes, G. M., Colley, L., O'Brien, K. A., Roberts, K. A., Agbaedeng, T. A., & Ross, M. D. (2020). The Role of MSC Therapy in Attenuating the Damaging Effects of the Cytokine Storm Induced by COVID-19 on the Heart and Cardiovascular System.. Frontiers in cardiovascular medicine, 7, 1-28.
    DOI WoS5 Europe PMC4
    2020 Noubiap, J. J., Agbaedeng, T. A., Nyaga, U. F., Nkoke, C., & Jingi, A. M. (2020). A meta-analytic evaluation of the diagnostic accuracy of the electrocardiographic Peguero-Lo Presti criterion for left ventricular hypertrophy.. J Clin Hypertens (Greenwich), 22(7), 1145-1153.
    DOI Scopus3 WoS3 Europe PMC2
    2020 Noubiap, J. J., Agbaedeng, T. A., Tochie, J. N., Nkeck, J. R., Ndoadoumgue, A. L., Fitzgerald, J. L., . . . Sanders, P. (2020). Meta-analysis comparing the frequency of carotid artery stenosis in patients with atrial fibrillation and vice versa. The American Journal of Cardiology, 138, 72-79.
    DOI WoS2
    2020 Roberts, K. A., Colley, L., Agbaedeng, T. A., Ellison-Hughes, G. M., & Ross, M. D. (2020). Vascular Manifestations of COVID-19 - Thromboembolism and Microvascular Dysfunction.. Front Cardiovasc Med, 7, 1-13.
    DOI WoS11 Europe PMC12
    2019 Oehmke, T. B., Wu, X. Y., Johnston, J. T., Gutiérrez, C., Patel, D., Moore, E. B., . . . Duong, M. T. (2019). Unique identities. Science (New York, N.Y.), 364(6435), 22-24.
    DOI
    2019 Agbaedeng, T. A. (2019). Resolve to overcome obstacles. SCIENCE, 364(6435), 23.
    2019 Agbaedeng, T. A., Wong, C. X., & Mahajan, R. (2019). Peri-atrial epicardial adipose tissue-a marker of thromboembolism?. Journal of Cardiovascular Electrophysiology, 30(11), 2217-2219.
    DOI
    2019 Munawar, D. A., Mahajan, R., Agbaedeng, T. A., Thiyagarajah, A., Twomey, D. J., Khokhar, K., . . . Sanders, P. (2019). Implication of ventricular pacing burden and atrial pacing therapies on the progression of atrial fibrillation: a systematic review and meta-analysis of randomized controlled trials. Heart rhythm, 16(8), 1204-1214.
    DOI Scopus2 WoS2
    2018 Agbaedeng, T. A., Linz, D., Lau, D. H., & Sanders, P. (2018). Unique role of epicardial adipose tissue in atrial fibrosis: “Atrial remodeling of a new sort”. Heart Rhythm, 15(11), 1728-1729.
    DOI Scopus2 WoS2 Europe PMC1
    2018 Mahajan, R., Nelson, A., Pathak, R. K., Middeldorp, M. E., Wong, C. X., Twomey, D. J., . . . Sanders, P. (2018). Electroanatomical remodeling of the atria in obesity: impact of adjacent epicardial fat. JACC: Clinical Electrophysiology, 4(12), 1529-1540.
    DOI Scopus47 WoS46 Europe PMC17
    2017 Thanigaimani, S., McLennan, E., Linz, D., Mahajan, R., Agbaedeng, T., Lee, G., . . . Lau, D. (2017). Progression and reversibility of stretch induced atrial remodeling: Characterization and clinical implications. Progress in Biophysics and Molecular Biology, 130(Pt B), 376-386.
    DOI Scopus15 WoS12 Europe PMC7
    2017 Thanigaimani, S., Lau, D., Agbaedeng, T., Elliott, A., Mahajan, R., & Sanders, P. (2017). Molecular mechanisms of atrial fibrosis: implications for the clinic. Expert review of cardiovascular therapy, 15(4), 247-256.
    DOI Scopus29 Europe PMC16
  • Conference Papers

    Year Citation
    2018 Agbaedeng, T., Mahajan, R., Thanigaimani, S., Mclennan, E., Twomey, D., Lau, D., & Sanders, P. (2018). Molecular characterisation of fibro-fatty infiltrations in the ventricular myocardium of obese sheep. In CARDIOVASCULAR RESEARCH Vol. 114 (pp. S11-S12). Vienna, AUSTRIA: OXFORD UNIV PRESS.
    2018 Khokhar, K. B., Lau, D., Elliott, A., Mahajan, R., Thiyagarajah, A., Munawar, D. A., . . . Sanders, P. (2018). Association of aortic stiffness and new onset AF-A meta-analysis. In EUROPEAN HEART JOURNAL Vol. 39 (pp. 420). Munich, GERMANY: OXFORD UNIV PRESS.
    2017 Agbaedeng, T. A., Mahajan, R., Munawar, D. A., Elliott, A., Twomey, D. J., Khokhar, K. B., . . . Sanders, P. (2017). Risk of sudden cardiac death in obesity: A systematic review and meta-analysis of emerging evidence. In EUROPEAN HEART JOURNAL Vol. 38 (pp. 1119). OXFORD UNIV PRESS.
    2017 Khokhar, K. B., Elliot, A., Stiles, M. K., Lau, D., Mahajan, R., Thiayagraj, A., . . . Sanders, P. (2017). Aortic stiffness in atrial fibrillation: q systematic review and meta-analysis. In EUROPEAN HEART JOURNAL Vol. 38 (pp. 756). OXFORD UNIV PRESS.
  • Conference Items

    Year Citation
    2019 Munawar, D. A., Mahajan, R., Agbaedeng, T. A., Khokar, K., Emami, M., Thiyagarajah, A., . . . Young, G. (2019). Incremental benefit of bi-directional block as an end point of Pulmonary Vein Isolation : One-year outcome of AF recurrence. Poster session presented at the meeting of EUROPEAN HEART JOURNAL SUPPLEMENTS. Indonesian Heart Assoc, Jakarta, INDONESIA: OXFORD UNIV PRESS.
    2019 Agbaedeng, T. A., Emami, M., Munawar, D. A., Rattanakosit, T., Khadim, K. I., Elliott, A., . . . Sanders, P. (2019). Fibrosis detected by late-gadolinium enhancement cardiac MRI is associated with atrial fibrillation and poorer ablation outcome: A meta-analysis. Poster session presented at the meeting of EUROPEAN HEART JOURNAL. Paris, FRANCE: OXFORD UNIV PRESS.
    2019 Agbaedeng, T. A., Twomey, D. J., Thanigaimani, S., Linz, D., Lau, D. H., Mahajan, R., & Sanders, P. (2019). Weight fluctuation demonstrates residual atrial arrhythmogenic substrate despite final weight loss in a chronic sheep model: implications for epicardial fat and fibrofatty infiltrates. Poster session presented at the meeting of EUROPEAN HEART JOURNAL. Paris, FRANCE: OXFORD UNIV PRESS.
    2017 Khokhar, K. B., Stiles, M., Elliott, A., Mahajan, R., Lau, D., Munawar, A., . . . Sanders, P. (2017). Aortic stiffness in atrial fibrillation: a systematic review and meta-analysis. Poster session presented at the meeting of Abstracts of the 65th Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand, as published in Heart, Lung and Circulation. Perth, Australia: Elsevier.
    DOI
    2016 Agbaedeng, T. A., Mahajan, R., Munawar, D. A., Elliott, A., Twomey, D. J., Kumar, S., . . . Sanders, P. (2016). Effects of epicardial fat and anterior fat pad removal on post-operative atrial fibrillation: a systematic review and meta-analysis. Poster session presented at the meeting of EUROPEAN HEART JOURNAL. Rome, ITALY: OXFORD UNIV PRESS.
    2016 Agbaedeng, T. A., Mahajan, R., Munawar, D. A., Elliott, A., Twomey, D. J., Kumar, S., . . . Sanders, P. (2016). Meta-analysis of effects of epicardial fat on atrial fibrillation and ablation outcome. Poster session presented at the meeting of Abstracts for the 64th Cardiac Society of Australia and New Zealand Annual Scientific Meeting and the International Society for Heart Research Australasian Section Annual Scientific Meeting, as published in Heart, Lung and Circulation. Adelaide, Australia: Elsevier.
    DOI
  • Co-Funding Contribution – Role of Adipokines in Cardiac Dysfunction ($100,000.00); The University of Adelaide – May 2021(CIA: Agbaedeng TA)
  • FHMS Emerging Leaders Grant ($40,000.00); The University of Adelaide – March 2021(CIA: Agbaedeng TA)
  • Tom Simpson Trust Fund for the purchase of a Multiskan Sky Microplate Spectrophotometer Reader ($22,500.00); Heart Foundation of Australia – January 2020 (CIA: Agbeaedeng TA)
  • CSANZ-BAYER Career Development Grant ($5,000.00); the Cardiac Society of Australia and New Zealand and Bayer Pharmaceutical; December 2019 – present (CIA: Agbaedeng TA)
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  • Other Supervision Activities

    Date Role Research Topic Location Program Supervision Type Student Load Student Name
    2020 - ongoing Principal Supervisor Conventional Adipocytokines and Stroke Risk The University of Adelaide Bachelor of Health and Medical Sciences Other Full Time Peter Iroga
    2020 - ongoing Principal Supervisor Adipocytokines and Atrial Fibrillation The University of Adelaide Bachelor of Health and Medical Sciences Other Full Time Anastasia L. Zachary
    2020 - ongoing Principal Supervisor Novel Adipocytokines and Stroke Risk The University of Adelaide Bachelor of Health and Medical Sciences Other Full Time Vishmi M. Rathnasekara
    2018 - 2018 Other MBBS Honours Research Tutorial The University of Adelaide MBBS Honours Research Tutorial Honours Part Time MBBS Honours Students
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  • Committee Memberships

    Date Role Committee Institution Country
    2020 - ongoing Member Founding Member - Early Career Investigator Committee International Society for Heart Research Australasian Section Australia
  • Memberships

    Date Role Membership Country
    2019 - ongoing Member American Physiological Society United States
    2019 - ongoing Member American Heart Association United States
    2017 - ongoing Member Cardiac Society of Australia and New Zealand, Affiliate Member Australia
    2017 - ongoing Member The Australian Society for Medical Research, Student Member Australia
    2017 - ongoing Member Asia Pacific Heart Rhythm Disorders, Associate Member Singapore
    2017 - ongoing Member American Association for the Advancement of Science (AAAS, Student Member United States
    2016 - ongoing Member The Cardiac Electrophysiology Society, Fellow-Trainee Member United States
    2016 - ongoing Member Heart Rhythm Society United States
  • Editorial Boards

    Date Role Editorial Board Name Institution Country
    2019 - ongoing Member Circulation: Arrhythmia and Electrophysiology Circulation - Arrhythmia and Electrophysiology United States
  • Review, Assessment, Editorial and Advice

    Date Title Type Institution Country
    2021 - ongoing European Journal of Preventive Cardiology (Journal Impact Factor [JIF] 7.8) Peer Review European Association of Preventive Cardiology France
    2020 - ongoing Frontiers in Cardiovascular Medicine (JIF 6.1) Peer Review Frontiers in Cardiovascular Medicine Switzerland
    2019 - ongoing Circulation: Arrhythmia and Electrophysiology (JIF 6.4) Peer Review Circulation: Arrhythmia and Electrophysiology United States
    2019 - ongoing Journal of Cardiovascular Electrophysiology (2019 JIF 2.4) Peer Review Journal of Cardiovascular Electrophysiology United States
    2019 - ongoing Laboratory Investigation (Journal Impact Factor 3.68) Peer Review Nature Publishing Group United States
    2019 - ongoing Journal of Clinical Medicine (Journal Impact Factor 5.69) Peer Review Multidisciplinary United States
    2019 - ongoing Journal of Applied Physiology (Journal Impact Factor 3.14) Peer Review American Physiological Society United States
    2019 - ongoing American Journal of Physiology - Heart and Circulatory Physiology (Journal Impact Factor 4.05) Peer Review American Physiological Society United States
  • Position: Postdoctoral Research Fellow
  • Phone: 81284488
  • Email: thomas.agbaedeng@adelaide.edu.au
  • Campus: North Terrace
  • Building: SAHMRI, floor 8
  • Org Unit: Adelaide Medical School

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