Higher Degree by Research Candidate
Adelaide Medical School
Faculty of Health and Medical Sciences
Tannith has a keen interest in reproductive cancers and the underlying mechanisms for developing chemotherapy resistance. Her project has developed from collaborating with domestic and international groups, to provide a multifaceted approach toward identifying novel biomarkers and therapeutic targets in high-grade serous ovarian cancer.
Novel Biomarker and therapeutic target identification in chemoresistant high-grade serous ovarian cancer.
Employment of Matrix-Assisted Laser Desorption Ionisation Mass Spectrometry (MALDI imaging) to investigate proteins upregulated in patient tissue collected at the time of relapse compared to the time of diagnosis.
Employment of Data Independent Acquisition Mass Spectrometry on an Ovarian cancer cohort from Munich, Germany, to identify clustering of biological functions and the proteins associated with disease progression and overall survival.
Date Institution name Country Title 2017 - 2017 The University of Adelaide Australia Bachelor of Health and Medical Sciences with First Class Honours 2013 - 2016 The University of Adelaide Australia Bachelor of Health Sciences
Date Title Institution Country 2018 Doctor of Philosophy Candidate The University of Adelaide Australia
Year Citation 2022 Acland, M., Lokman, N. A., Young, C., Anderson, D., Condina, M., Desire, C., . . . Klingler-Hoffmann, M. (2022). Chemoresistant Cancer Cell Lines Are Characterized by Migratory, Amino Acid Metabolism, Protein Catabolism and IFN1 Signalling Perturbations. Cancers, 14(11), 2763-1-2763-24.
2021 Wang, W., Lokman, N. A., Noye, T. M., Macpherson, A. M., Oehler, M. K., & Ricciardelli, C. (2021). ABCA1 is associated with the development of acquired chemotherapy resistance and predicts poor ovarian cancer outcome. Cancer Drug Resistance, 4(2), 485-502.
2018 Noye, T. M., Lokman, N. A., Oehler, M. K., & Ricciardelli, C. (2018). S100A10 and cancer hallmarks: Structure, functions, and its emerging role in Ovarian cancer. International Journal of Molecular Sciences, 19(12), 16 pages.
DOI Scopus21 WoS21 Europe PMC12
Beat Cancer Project- Travel grant.
Date Role Membership Country 2022 - ongoing Member Australian New Zealand Gynaecological group Australia 2021 - ongoing Member Australasian Metastasis Research Society Australia 2021 - ongoing Member Australasian Proteomics Society Australia 2020 - ongoing Member American Association for Cancer Research United States 2017 - ongoing Member Robinson Research Institute Australia
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