Tanja Jankovic-Karasoulos

Dr Tanja Jankovic-Karasoulos

NHMRC Externally-Funded Research Fellow

School of Pharmacy and Biomedical Sciences

College of Health

Eligible to supervise Masters and PhD - email supervisor to discuss availability.

Head: One-Carbon Metabolism in Pregnancy and Disease 
Investigating how nutrient-driven one-carbon metabolism shapes pregnancy physiology and long-term disease risk.
 
I lead a translational research program within the Robinson Research Institute and College of Health, investigating how nutrient exposures during pregnancy regulate one-carbon metabolism and, in turn, shape placental function, maternal metabolic adaptation, pregnancy outcomes and the long-term health of mothers and their children. Within this broader program, my group focuses on establishing the biological and health consequences of excessive exposure to folic acid, the synthetic form of folate.
By integrating mechanistic laboratory models with human cohort and interventional studies, we define how population-level folic acid exposures, including dietary supplementation and national food fortification, modify disease risk during pregnancy (particularly gestational diabetes), influence fetal programming, and contribute to long-term cardiometabolic risk in mothers and broader disease susceptibility in offspring. Through identifying biologically meaningful exposure thresholds and critical windows of vulnerability, our research aims to inform precision nutrition strategies and evidence-based public health policy in populations with widespread folic acid exposure.
 
Alongside our work in nutrient signalling, we collaborate across Adelaide University to investigate how viral infections, including Zika virus, disrupt placental morphology, immune responses and developmental outcomes in early- to mid-gestation.
 
Student Opportunities
A funded PhD scholarship is available to commence in 2026 and will investigate how folate and folic acid exposures alter placental function and maternal metabolic regulation in the context of gestational diabetes. Projects may incorporate mechanistic laboratory studies, clinical cohort analyses, or integrated translational approaches.
Additional Honours and PhD opportunities are available across our program in one-carbon metabolism, pregnancy and disease. Projects are flexible and can be tailored to align with candidates’ interests and methodological strengths within the broader scope of our research.
 

Year Citation
2026 Van der Hoek, K. H., Jankovic-Karasoulos, T., McCullough, D., Coldbeck-Shackley, R. C., Eyre, N. S., Roberts, C. T., & Beard, M. R. (2026). Correction: The first trimester human placenta responds to Zika virus infection inducing an interferon (IFN) and antiviral interferon stimulated gene (ISG) response (Virology Journal, (2025), 22, 1, (108), 10.1186/s12985-025-02729-3). Virology Journal, 23(1), 4 pages.
DOI
2026 Akbarzadeh, I., Heidari, F., Nwoke, S., Liu, C., Jankovic-Karasoulos, T., & McClements, L. (2026). Angiogenic Imbalance Models of Preeclampsia: From Mechanisms to Clinics.. Hypertension, 83(7), e26316.
DOI Scopus2 WoS1
2026 Wang, H., Leemaqz, S., Smith, M. D., McCullough, D., Arthurs, A. L., Jankovic-Karasoulos, T., . . . Roberts, C. T. (2026). High folic acid supplementation is associated with vaginal bleeding in early pregnancy in a fetal sex-specific manner: findings from two prospective cohort studies. Reproductive Health, 23(1), 134-1-134-13.
DOI
2026 Williamson, J. M., Arthurs, A. L., Smith, M. D., Leemaqz, S., Phillips-Hughes, A., McCullough, D., . . . Jankovic-Karasoulos, T. (2026). Excess folic acid disrupts placental endocrine function in vitro: a potential mechanism linking elevated folic acid exposure with gestational diabetes mellitus. Frontiers in Nutrition, 13, 12 pages.
DOI
2025 Arthurs, A. L., Dietrich, B., Knöfler, M., Lushington, C. J., Thomas, P. Q., Adikusuma, F., . . . Roberts, C. T. (2025). Genetically edited human placental organoids cast new light on the role of ACE2. Cell Death and Disease, 16(1), 78-1-78-12.
DOI Scopus3 WoS3 Europe PMC6
2025 Van Der Hoek, K. H., Jankovic-Karasoulos, T., McCullough, D., Coldbeck-Shackley, R. C., Eyre, N. S., Roberts, C. T., & Beard, M. R. (2025). The first trimester human placenta responds to Zika virus infection inducing an interferon (IFN) and antiviral interferon stimulated gene (ISG) response. Virology Journal, 22(1), 108-1-108-15.
DOI Scopus4 WoS4 Europe PMC4
2025 Arthurs, A. L., Jackson, M. R., McCULLOUGH, D., Scott, H. S., Barnett, C. P., Webb, S. T., . . . Roberts, C. T. (2025). Circular RNAs accumulate in aging human placental tissue and in stillbirth, leading to DNA damage and cellular senescence.. American journal of obstetrics and gynecology, 234(1), S0002-9378(25)00587-3.
DOI Scopus3 WoS1 Europe PMC2
2025 Jankovic-Karasoulos, T., Smith, M. D., Leemaqz, S., Mittinty, M., Williamson, J., McCullough, D., . . . Roberts, C. T. (2025). Maternal Folate Excess, Placental Hormones, and Gestational Diabetes Mellitus: Findings from Prospective Cohorts Before and After Mandatory Folic Acid Food Fortification. Nutrients, 17(17), 2863-1-2863-16.
DOI Scopus4 WoS4 Europe PMC3
2025 Smith, M. D., Plaisier, S., Breen, J., Bogias, K. J., Jankovic-Karasoulos, T., McCullough, D., . . . Roberts, C. T. (2025). Sex-specific placental transcriptome alterations in late-onset preeclampsia reveal male-biased immune and metabolic dysregulation. Biology of Sex Differences, 17(1), 8-1-8-22.
DOI Scopus4 WoS2 Europe PMC1
2023 Smith, M. D., Leemaqz, S. Y., Jankovic-Karasoulos, T., McCullough, D., McAninch, D., Arthurs, A. L., . . . Pillman, K. A. (2023). DraculR: A Web-Based Application for In Silico Haemolysis Detection in High-Throughput microRNA Sequencing Data. Genes, 14(2), 1-10.
DOI Scopus4 WoS3 Europe PMC3
2023 Jankovic-Karasoulos, T., Smith, M. D., Leemaqz, S., Williamson, J., McCullough, D., Arthurs, A. L., . . . Roberts, C. T. (2023). Elevated Maternal Folate Status and Changes in Maternal Prolactin, Placental Lactogen and Placental Growth Hormone Following Folic Acid Food Fortification: Evidence from Two Prospective Pregnancy Cohorts. Nutrients, 15(7), 1553.
DOI Scopus11 WoS11 Europe PMC10
2023 Arthurs, A. L., McCullough, D., Williamson, J. M., Jankovic-Karasoulos, T., Smith, M. D., & Roberts, C. T. (2023). Factors influencing RNA yield from placenta tissue. Placenta, 140, 80-83.
DOI Scopus6 WoS6 Europe PMC7
2022 Bogias, J., Pederson, S., Leemaqz, S., Smith, M., McAninch, D., Jankovic-Karasoulos, T., . . . Roberts, C. (2022). Placental transcription profiling in 6-23 weeks’ gestation reveals differential transcript usage in early development.
DOI
2022 Smith, M., Leemaqz, S., Jankovic-Karasoulos, T., McCullough, D., McAninch, D., Breen, J., . . . Pillman, K. (2022). DraculR: A web based application for <i>in silico</i> haemolysis detection in high throughput small RNA sequencing data.
DOI
2022 Arthurs, A. L., Smith, M. D., Hintural, M. D., Breen, J., McCullough, D., Thornton, F. I., . . . Roberts, C. T. (2022). Placental Inflammasome mRNA Levels Differ by Mode of Delivery and Fetal Sex. Frontiers in immunology, 13, 1-15.
DOI Scopus8 WoS8 Europe PMC8
2022 Bogias, K. J., Pederson, S. M., Leemaqz, S., Smith, M. D., McAninch, D., Jankovic-Karasoulos, T., . . . Roberts, C. T. (2022). Placental Transcription Profiling in 6–23 Weeks’ Gestation Reveals Differential Transcript Usage in Early Development. International Journal of Molecular Sciences, 23(9), 17 pages.
DOI Scopus6 WoS6 Europe PMC6
2022 Smith, M., Leemaqz, S., Jankovic-Karasoulos, T., McAninch, D., McCullough, D., Breen, J., . . . Pillman, K. (2022). Haemolysis detection in microRNA-seq from clinical plasma samples.
DOI
2022 Arthurs, A. L., Jankovic-Karasoulos, T., Smith, M. D., & Roberts, C. T. (2022). Circular RNAs in Pregnancy and the Placenta. International Journal of Molecular Sciences, 23(9), 4551-1-4551-20.
DOI Scopus14 WoS14 Europe PMC14
2022 Smith, M. D., Leemaqz, S. Y., Jankovic-Karasoulos, T., McAninch, D., McCullough, D., Breen, J., . . . Pillman, K. A. (2022). Haemolysis Detection in MicroRNA-Seq from Clinical Plasma Samples. Genes, 13(7), 1288-1-1288-15.
DOI Scopus21 WoS20 Europe PMC18
2022 Williamson, J. M., Arthurs, A. L., Smith, M. D., Roberts, C. T., & Jankovic-Karasoulos, T. (2022). High Folate, Perturbed One-Carbon Metabolism and Gestational Diabetes Mellitus. Nutrients, 14(19), 1-24.
DOI Scopus53 WoS52 Europe PMC43
2021 Jankovic-Karasoulos, T., Furness, D. L., Leemaqz, S. Y., Dekker, G. A., Grzeskowiak, L. E., Grieger, J. A., . . . Roberts, C. T. (2021). Maternal folate, one-carbon metabolism and pregnancy outcomes. Maternal and Child Nutrition, 17(1), 1-17.
DOI Scopus76 WoS71 Europe PMC59
2021 Jankovic-Karasoulos, T., McAninch, D., Dixon, C., Leemaqz, S. Y. -L., François, M., Leifert, W. R., . . . Bianco-Miotto, T. (2021). The effect of zinc on human trophoblast proliferation and oxidative stress. The Journal of Nutritional Biochemistry, 90, 1-10.
DOI Scopus2 WoS4 Europe PMC3
2021 Roberts, C. T., Jankovic-Karasoulos, T., & Arthurs, A. L. (2021). Is the US failing women?. EClinicalMedicine, 31, 100701-1-100701-2.
DOI Scopus3 WoS3 Europe PMC3
2021 Habibi, N., Labrinidis, A., Leemaqz, S. Y. -L., Jankovic-Karasoulos, T., McCullough, D., Grieger, J. A., . . . Bianco-Miotto, T. (2021). Effect of selenium and iodine on oxidative stress in the first trimester human placenta explants. Nutrients, 13(3), 1-14.
DOI Scopus9 WoS9 Europe PMC7
2021 Winter, M., Jankovic-Karasoulos, T., Roberts, C. T., Bianco-Miotto, T., & Thierry, B. (2021). Bioengineered microphysiological placental models: towards improving understanding of pregnancy health and disease. Trends in Biotechnology, 39(11), 1221-1235.
DOI Scopus12 WoS12 Europe PMC10
2021 Smith, M. D., Pillman, K., Jankovic-Karasoulos, T., McAninch, D., Wan, Q., Bogias, K. J., . . . Roberts, C. T. (2021). Large-scale transcriptome-wide profiling of microRNAs in human placenta and maternal plasma at early to mid gestation. RNA biology, 18(Suppl. 1), 507-520.
DOI Scopus23 WoS26 Europe PMC29
2021 Arthurs, A. L., Jankovic-Karasoulos, T., & Roberts, C. T. (2021). COVID-19 in pregnancy: What we know from the first year of the pandemic. Biochimica et Biophysica Acta (BBA): Molecular Basis of Disease, 1867(12), 166248-1-166248-8.
DOI Scopus18 WoS15 Europe PMC22
2020 Jankovic-Karasoulos, T., Bianco-Miotto, T., Butler, M. S., Butler, L. M., McNeil, C. M., O'Toole, S. A., . . . Ricciardelli, C. (2020). Elevated levels of tumor apolipoprotein D independently predict poor outcome in breast cancer patients. Histopathology, 76(7), 976-987.
DOI Scopus35 WoS32 Europe PMC33
2020 Mulder, C., Lassi, Z. S., Grieger, J. A., Bachlani, A., Jankovic-Karasoulos, T., Roberts, C. T., & Andraweera, P. H. (2020). Cardio-metabolic risk factors among young infertile women: a systematic review and meta-analysis. BJOG: an International Journal of Obstetrics and Gynaecology, 127(8), 930-939.
DOI Scopus32 WoS28 Europe PMC28
2020 Habibi, N., Jankovic-Karasoulos, T., Leemaqz, S. Y. L., Francois, M., Zhou, S. J., Leifert, W. R., . . . Bianco-Miotto, T. (2020). Effect of iodine and selenium on proliferation, viability, and oxidative stress in HTR-8/SVneo placental cells. Biological Trace Element Research, 199(4), 1332-1344.
DOI Scopus16 WoS14 Europe PMC8
2020 Smith, M., Pillman, K., Jankovic-Karasoulos, T., McAninch, D., Wan, Q., Bogias, J., . . . Roberts, C. (2020). Large-scale transcriptome-wide profiling of microRNAs in human placenta and maternal plasma at early to mid gestation.
DOI Europe PMC1
2020 Breen, J., McAninch, D., Jankovic-Karasoulos, T., McCullough, D., Smith, M., Bogias, K. J., . . . Roberts, C. (2020). Temporal placental genome wide expression profiles reflect three phases of utero-placental blood flow during early to mid human gestation.
DOI Europe PMC2
2020 Habibi, N., Bianco-Miotto, T., Phoi, Y. Y., Jankovic-Karasoulos, T., Roberts, C. T., & Grieger, J. A. (2020). Maternal diet and offspring telomere length: a systematic review.. Nutr Rev, 79(2), 148-159.
DOI Scopus15 WoS14 Europe PMC14
2019 Wilson, R. L., François, M., Jankovic-Karasoulos, T., McAninch, D., McCullough, D., Leifert, W. R., . . . Bianco-Miotto, T. (2019). Characterization of 5-methylcytosine and 5-hydroxymethylcytosine in human placenta cell types across gestation. Epigenetics, 14(7), 660-671.
DOI Scopus14 WoS12 Europe PMC14
2019 Grieger, J. A., Grzeskowiak, L. E., Wilson, R. L., Bianco-Miotto, T., Leemaqz, S. Y., Jankovic-Karasoulos, T., . . . Roberts, C. T. (2019). Maternal selenium, copper and zinc concentrations in early pregnancy, and the association with fertility. Nutrients, 11(7), 1-12.
DOI Scopus56 WoS50 Europe PMC52
2019 Wan, Q., Yiner-Lee Leemaqz, S., Pederson, S. M., McCullough, D., McAninch, D. C., Jankovic-Karasoulos, T., . . . Bianco-Miotto, T. (2019). Quality control measures for placental sample purity in DNA methylation array analyses.. Placenta, 88, 8-11.
DOI Scopus3 WoS2 Europe PMC3
2018 Grieger, J., Grzeskowiak, L., Bianco-Miotto, T., Jankovic-Karasoulos, T., Moran, L., Wilson, R., . . . Roberts, C. (2018). Pre-pregnancy fast food and fruit intake is associated with time to pregnancy. Human Reproduction, 33(6), 1063-1070.
DOI Scopus57 WoS52 Europe PMC46
2018 Jankovic-Karasoulos, T., McAninch, D., McCullough, D., Wilson, R. L., Bianco-Miotto, T., & Roberts, C. T. (2018). Isolation of villous cytotrophoblasts from second trimester human placentas. Placenta, 74, 55-58.
DOI Scopus3 WoS2 Europe PMC2
2017 Van Der Hoek, K., Eyre, N., Shue, B., Khantisitthiporn, O., Glab-Ampi, K., Carr, J., . . . Beard, M. (2017). Viperin is an important host restriction factor in control of Zika virus infection. Scientific Reports, 7(1), 4475 -1-4475-14.
DOI Scopus98 WoS96 Europe PMC92
2017 Wilson, R., Leemaqz, S., Goh, Z., McAninch, D., Jankovic-Karasoulos, T., Leghi, G., . . . Roberts, C. (2017). Zinc is a critical regulator of placental morphogenesis and maternal hemodynamics during pregnancy in mice. Scientific Reports, 7(1), 15137-1-15137-14.
DOI Scopus36 WoS28 Europe PMC29
2014 Ochnik, A., Moore, N., Jankovic-Karasoulos, T., Bianco-Miotto, T., Ryan, N., Thomas, M., . . . Hickey, T. (2014). Antiandrogenic actions of medroxyprogesterone acetate on epithelial cells within normal human breast tissues cultured ex vivo. Menopause, 21(1), 79-88.
DOI Scopus19 WoS16 Europe PMC17
2013 Bayliss, J., Karasoulos, T., & McLean, C. A. (2013). Immunosuppression increases JC polyomavirus large T antigen DNA load in the brains of patients without progressive multifocal leukoencephalopathy. Journal of Infectious Diseases, 207(1), 133-136.
DOI Scopus16 WoS17 Europe PMC16
2012 Bayliss, J., Karasoulos, T., & McLean, C. A. (2012). Frequency and large T (LT) sequence of JC polyomavirus DNA in oligodendrocytes, astrocytes and granular cells in non-PML brain. Brain Pathology, 22(3), 329-336.
DOI Scopus18 WoS17 Europe PMC17
2011 Bayliss, J., Karasoulos, T., Bowden, S., Glogowski, I., & Mclean, C. A. (2011). Immunosuppression increases latent infection of brain by JC polyomavirus. Pathology, 43(4), 362-367.
DOI Scopus25 WoS24 Europe PMC22
2010 Ochnik, A. M., Jankovic-Karasoulos, T., Cops, E. J., Birrell, S. N., Butler, L. M., Jindall, S., . . . Hickey, T. E. (2010). Medroxyprogesterone acetate impedes 5 alpha-dihydrotesterone induced androgen receptor signaling in normal and malignant human breast epithelial cells. Cancer Research, 70(Suppl 8), 4 pages.
DOI
2009 Thompson, K. A., Varrone, J. J., Jankovic-Karasoulos, T., Wesselingh, S. L., & McLean, C. A. (2009). Cell-specific temporal infection of the brain in a simian immunodeficiency virus model of human immunodeficiency virus encephalitis. Journal of Neurovirology, 15(4), 300-311.
DOI Scopus14 WoS13 Europe PMC15
2006 Abstracts of the XVIth Congress of the International Society of Neuropathology. San Francisco, California, USA. September 10-15, 2006. (2006). Brain pathology (Zurich, Switzerland), 16 Suppl 1(Suppl 1), S1-172.
DOI
2003 Reeson, A., Jankovic-Karasoulos, T., Kasper, M., Rogers, S., & Austin, A. (2003). Application of 16S rDNA-DGGE to examine the microbial ecology associated with a social wasp Vespula germanica. Insect Molecular Biology, 12(1), 85-91.
DOI Scopus87 WoS79 Europe PMC52

Year Citation
2025 Roberts, C., Leemaqz, S., Jankovic-Karasoulos, T., Mccullough, D., Williamson, J., Arthurs, A., . . . Mittinty, M. (2025). EARLY PREGNANCY METABOLIC SYNDROME, FOLATE AND VITAMIN D STATUS, PLACENTAL HORMONES AND GESTATIONAL DIABETES.. In PLACENTA Vol. 171 (pp. 1 page). W B SAUNDERS CO LTD.
2024 Smith, M., Plasier, S., Jankovic-Karasoulos, T., Williamson, J., Leemaqz, S., Arthurs, A., . . . Pillman, K. (2024). TOWARDS ESTABLISHING COMMUNITY STANDARDS FOR BIOINFORMATIC ANALYSIS OF THE HUMAN PLACENTA. In PLACENTA Vol. 154 (pp. E59). CANADA, Montreal: W B SAUNDERS CO LTD.
2024 Jankovic-Karasoulos, T., Smith, M., Leemaqz, S., Mittinity, M., Williamson, J., McCullough, D., . . . Roberts, C. (2024). MATERNAL FOLATE STATUS AND THE PREVALENCE OF GESTATIONAL DIABETES MELLITUS: INSIGHTS FROM AUSTRALIAN PREGNANCY COHORTS. In PLACENTA Vol. 154 (pp. E65). W B SAUNDERS CO LTD.
2024 Williamson, J., Arthurs, A., Smith, M., Leemaqz, S., McCullough, D., Roberts, C., & Jankovic-Karasoulos, T. (2024). EXCESS FOLIC ACID MIMICS DEFICIENCY IN HUMAN PLACENTA <i>IN VITRO</i>. In PLACENTA Vol. 154 (pp. E64-E65). W B SAUNDERS CO LTD.
2023 Smith, M., Pillman, K., Leemaqz, S., Arthurs, A., McCullough, D., Williamson, J., . . . Roberts, C. (2023). SEX-SPECIFIC ANALYSIS OF PLACENTAL GENE EXPRESSION IN LATE-ONSET PREECLAMPSIA. In PLACENTA Vol. 140 (pp. E16-E17). Rotorua, NEW ZEALAND: W B SAUNDERS CO LTD.
2023 Jankovic-Karasoulos, T., Leemaqz, S., Smith, M., Williamson, J., McCullough, D., Arthurs, A., . . . Roberts, C. (2023). FOLIC ACID FOOD FORTIFICATION, MATERNAL ENDOCRINE STATUS AND GESTATIONAL DIABETES MELLITUS. In PLACENTA Vol. 140 (pp. E80). Rotorua, NEW ZEALAND: W B SAUNDERS CO LTD.
2023 Roberts, C., Leemaqz, S., Arthurs, A., Jankovic-Karasoulos, T., McCullough, D., Smith, M., & Dekker, G. (2023). MATERNAL DISADVANTAGE AND PREGNANCY OUTCOMES IN TWO AUSTRALIAN PREGNANCY COHORTS. In PLACENTA Vol. 140 (pp. E9). Rotorua, NEW ZEALAND: W B SAUNDERS CO LTD.
2023 Jankovic-Karasoulos, T., Leemaqz, S., Smith, M. D., Williamson, J., McCullough, D., Arthurs, A. L., . . . Roberts, C. T. (2023). Folic Acid Food Fortification, Placental Hormones and Gestational Diabetes Mellitus. In REPRODUCTIVE SCIENCES Vol. 30 (pp. 159A). AUSTRALIA, Brisbane: SPRINGER HEIDELBERG.
2017 Wilson, R. L., Jankovic-Karasoulous, T., McAninch, D., Roberts, C. T., & Bianco-Miotto, T. (2017). IMMUNOLOCALISATION OF 5-METHYLCYTOSINE AND 5HYDROXYMETHYLCYTOSINE IN THE PLACENTA ACROSS GESTATION REVEALS DYNAMIC CO -LOCALISATION OF EXPRESSION. In PLACENTA Vol. 57 (pp. 260-261). ENGLAND, Manchester: W B SAUNDERS CO LTD.
DOI
2010 Bayliss, J., Jankovic-Karasoulos, T., Bowden, S., Glogowski, I., & McLean, C. A. (2010). Latent brain JC polyomavirus: the role of immunosuppression and site of viral latency. In BRAIN PATHOLOGY Vol. 20 (pp. 81). Salzburg, AUSTRIA: WILEY-BLACKWELL PUBLISHING, INC.
2010 Bayliss, J., Karasoulos, T., Bowden, S., Glogowski, I., & McLean, C. A. (2010). Immunosuppression Increases Latent Infection of Brain by JC Polyomavirus. In JOURNAL OF NEUROVIROLOGY Vol. 16 (pp. 8). ITALY, Milan: SPRINGER.
2006 Thompson, K. A., McLean, C. A., Jankovic-Karasoulos, T., Mankowski, J. L., & Zink, M. C. (2006). Early CNS entry by HIV-1 infected perivascular macrophages does not result in a viral reservoir in an SIV model of HIV. In BRAIN PATHOLOGY Vol. 16 (pp. S14). CA, San Francisco: BLACKWELL PUBLISHING.

Year Citation
2025 Williamson, J., Arthurs, A., Smith, M., Merriman, A., Leemaqz, S., McCullough, D., . . . Jankovic-Karasoulos, T. (2025). The parallel relationship between folic acid deficiency and excess in human placental endocrine function: understanding the role of folate metabolism. Poster session presented at the meeting of Abstacts of the Annual Conference of the International Federation of Placenta Associations, as published in Placenta. United Kingdom: Elsevier.
DOI
2020 Breen, J., Smith, M., McAninch, D., Jankovic-Karasoulos, T., McCullough, D., Pederson, S. M., . . . Roberts, C. (2020). Defining Co-expression Patterns and Molecular Pathways of the Placenta During Early Pregnancy.. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. Vancouver, CANADA: SPRINGER HEIDELBERG.
2020 Wan, Q., Breen, J., Leemaqz, S. Y. -L., Pederson, S. M., Jankovic-Karasoulos, T., McAninch, D. C., . . . Bianco-Miotto, T. (2020). Characterisation of Placental DNA Methylation Across Early Human Gestation.. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. Vancouver, CANADA: SPRINGER HEIDELBERG.
2020 Roberts, C. T., Leemaqz, S., Jankovic-Karasoulos, T., Grieger, J., McCullough, D., & Dekker, G. (2020). Rising Gestational Diabetes Mellitus: It's Not Just About Maternal Obesity. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. Vancouver, CANADA: SPRINGER HEIDELBERG.
2016 Wilson, R., Leemaqz, S., Goh, Z., McAninch, D., Jankovic-Karasoulos, T., Bianco-Miotto, T., & Roberts, C. (2016). ZINC DEFICIENCY ALTERS PLACENTAL DEVELOPMENT AND MATERNAL HEMODYNAMICS CONTRIBUTING TO FETAL GROWTH RESTRICTION IN MICE. Poster session presented at the meeting of PLACENTA. Portland, OR: W B SAUNDERS CO LTD.
DOI
2009 Jankovic-Karasoulos, T., Birrell, S. N., Cops, E. J., Jindal, S., Ochnik, A., Thomas, M., . . . Hickey, T. E. (2009). Evaluation of testosterone supplementation during anastrozole therapy in a breast explant model. Poster session presented at the meeting of Cancer Research. San Antonio, Texas: American Association for Cancer Research.
DOI

Year Citation
2025 Jankovic-Karasoulos, T., Smith, M., Leemaqz, S., Mittinty, M., Williamson, J., McCullough, D., . . . Roberts, C. (2025). Folate Overload and the Placental Hormone Axis: A Hidden Risk for Gestational Diabetes Mellitus.
DOI
2024 Arthurs, A., Dietrich, B., Knöfler, M., Lushington, C., Thomas, P., Adikusuma, F., . . . Roberts, C. (2024). Genetically edited human placental organoids cast new light on the role of ACE2 in placental development.
DOI Europe PMC1
2024 Arthurs, A., Jackson, M., McCullough, D., Scott, H., Barnett, C., Webb, S., . . . Roberts, C. (2024). Circular RNAs accumulate in ageing human placental tissue and in stillbirth, leading to DNA damage and cellular senescence.
DOI

An NHMRC Ideas Grant (2025–2029) was awarded to CIA Dr. Tanja Jankovic-Karasoulos and her colleagues at Adelaide University and Flinders University, to undertake the study titled ‘Too Much of a Good Thing? Examining the Impacts of Folic Acid Supplementation After the First Trimester on Placental Endocrine Function and Insulin Resistance During Pregnancy. $1,173,927

A Diabetes Australia General Grant (2025) was awarded to CIA Dr. Tanja Jankovic-Karasoulos to investigate the molecular targets of folic acid in the placenta. $60,000

MRFF 2024 TTRA - Cardiovascular Disease and Diabetes Mechanisms (2024-2026; CIB). Impact of excess folic acid on the pathogenesis of gestational diabetes. $1,033,299

Flinders Foundation (2024-2025; CIA). Decoding folic acid impact on gestational diabetes risk in Australia. $24,816

Channel 7 Children's Research Foundation (2024; CIC). Circular RNAs indicate placental ageing, signalling stillbirth risk and infant morbidity in survivors. $40,000

NHMRC Synergy (2023-2027; AI). Using complex models of human trophoblast to study placental biology and disease. $5,000,000

Hospital Research Foundation (2022-2023; CIB). Characterising the role of pregnancy zone protein in the clearance of preeclampsia-associated misfolded protein. $141,126

Flinders Foundation (2022; CIC). Characterising the relationship between pregnancy zone protein and preeclampsia. $25,000

Flinders Foundation (2022; CIA). Human placental endocrine response to folic acid. $25,000

Flinders Foundation (2020; CIB). Assessment of PFAS toxicity in human placenta. $24,940

Flinders Foundation (2020; CIC). How do circular RNAs in the placenta contribute to pregnancy complications. $24,960


 

2020-2025 The University of Adelaide. Guest lectures and tutorials in Obstetrics and Gynaecology 3001: Reproductive Biology.

2021-2022 Flinders University. Guest lectures in MMED2931/MMED8931: Reproductive Physiology

Date Role Research Topic Program Degree Type Student Load Student Name
2026 Principal Supervisor Mechanistic Insights into Folic Acid Effects on Placental Function and Gestational Diabetes Risk: Integrating In Vitro, In Vivo and Clinical Studies Doctor of Philosophy Doctorate Full Time Miss Miranda Shoubridge
2018 Co-Supervisor Impact of Maternal Micronutrient Deficiency on Placental Function and Pregnancy Outcome Doctor of Philosophy Doctorate Full Time Mrs Martha Menberu

Date Role Research Topic Program Degree Type Student Load Student Name
2018 - 2020 Co-Supervisor The Effect of Micronutrients in Oxidative Stress, Proliferation and Apoptosis in Placenta Doctor of Philosophy Doctorate Full Time Ms Nahal Habibi

Date Role Research Topic Location Program Supervision Type Student Load Student Name
2024 - ongoing Principal Supervisor Investigating the effects of high folic acid on placental folate metabolism Flinders University Medical Studies - 2 Year Research Project Other Full Time Alexander Phillips-Hughes
2022 - ongoing Co-Supervisor Folic acid regulation of placental function Flinders University - Doctorate Full Time Miss Jessica Williamson
2022 - 2024 Principal Supervisor Folic acid food fortification and pregnancy health Flinders University Medical Studies - 2 Year Research Project Other Full Time Madeleine Veitch
2021 - ongoing Co-Supervisor Investigating the role of Pregnancy Zone Protein in Preeclampsia Flinders University - Doctorate Full Time Demi Georgiou

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