Dr Takashi Okada
Senior Research Fellow
School of Biomedicine
Faculty of Health and Medical Sciences
Takashi completed his PhD at the Tohoku University Japan for his study on immunological and biological characterization of Brassica pollen allergen. Then, he worked as a pos-doc fellow at University of Melbourne for transcriptome analysis of male gametic cells and identification of male gamete-specific histone H3. He also worked as a senior pos-doc fellow in CSIRO for genetic analysis of asexual seed formation induced by unreduced gamete formation and parthenogenesis. He joined University of Adelaide in 2012, working as a unit leader of the DuPont Pioneer Hybrid Wheat Project, focused on floral architecture. Since December 2019, he has been working on the current project in the Robinson Research Institute at the School of Biomedicine.
Takashi has expertise in molecular biology, developmental and reproductive biology, genetics and bioinformatics. He has been working on multiple scientific research projects for animal and plant reproduction. His current project in the Mitochondrial Genetics group at the School of Biomedicine aims to understand the effect of mitochondrial deficiency and supplementation in oocytes on fertility and reproductive outcomes using pig model. His research addresses 1) how mitochondrial deficiency in oocytes affect transcriptome profile in pig oocytes; 2) if mitochondrial supplementation in oocytes changes DNA methylation profile in embryo; and 3) how mitochondrial supplementation influences gene expression in embryo and adult tissues. He also addresses a 40-year debate over DNA methylation in mammalian mitochondrial genome.
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Appointments
Date Position Institution name 2019 - ongoing NHMRC Grant Pos-doc Fellow Robinson Research Institute 2012 - 2019 Research Fellow Plant Genomics Centre 2008 - 2012 Research Fellow CSIRO 2005 - 2008 Post Doctoral Research Fellow CSIRO 2000 - 2004 Post Doctoral Research Fellow University of Melbourne -
Language Competencies
Language Competency English Can read, write, speak, understand spoken and peer review Japanese Can read, write, speak, understand spoken and peer review -
Education
Date Institution name Country Title 1997 - 2000 Tohoku University, Sendai-shi Japan PhD 1995 - 1997 Tohoku University Japan M.Sc. 1990 - 1995 Tohoku University Japan B.Sc -
Research Interests
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Journals
Year Citation 2023 McIlfatrick, S., O'Leary, S., Okada, T., Penn, A., Nguyen, V. H. T., McKenny, L., . . . St. John, J. C. (2023). Does supplementation of oocytes with additional mtDNA influence developmental outcome?. iScience, 26(2), 105956-1-105956-27.
Scopus1 WoS1 Europe PMC12023 Okada, T., McIlfatrick, S., & St. John, J. C. (2023). Mitochondrial DNA Deficiency and Supplementation in Sus scrofa Oocytes Influence Transcriptome Profiles in Oocytes and Blastocysts. International Journal of Molecular Sciences, 24(4), 1-26.
Scopus1 WoS1 Europe PMC12023 Okada, T., Penn, A., & St. John, J. C. (2023). Mitochondrial DNA Supplementation of Oocytes Has Downstream Effects on the Transcriptional Profiles of Sus scrofa Adult Tissues with High mtDNA Copy Number. International Journal of Molecular Sciences, 24(8), 7545.
2022 Okada, T., Sun, X., McIlfatrick, S., & St. John, J. C. (2022). Low guanine content and biased nucleotide distribution in vertebrate mtDNA can cause overestimation of non-CpG methylation. NAR Genomics and Bioinformatics, 4(1), 1-17.
Scopus12022 Okada, T., McIlfatrick, S., Hin, N., Aryamanesh, N., Breen, J., & St John, J. C. (2022). Mitochondrial supplementation of Sus scrofa metaphase II oocytes alters DNA methylation and gene expression profiles of blastocysts. Epigenetics and Chromatin, 15(1), 20 pages.
Scopus7 WoS6 Europe PMC42022 St John, J. C., Okada, T., Andreas, E., & Penn, A. (2022). The role of mtDNA in oocyte quality and embryo development. Molecular Reproduction and Development, 90(7), 621-633.
Scopus4 WoS3 Europe PMC32021 Okada, T., Jayasinghe, R. M., Eckermann, P., Watson-Haigh, N. S., Warner, P., Williams, M. E., . . . Whitford, R. (2021). Genetic factors associated with favourable pollinator traits in the wheat cultivar Piko. FUNCTIONAL PLANT BIOLOGY, 48(4), 434-447.
Scopus2 WoS3 Europe PMC32020 Kapetanovic, R., Afroz, S. F., Ramnath, D., Lawrence, G. M. E. P., Okada, T., Curson, J. E. B., . . . Sweet, M. J. (2020). Lipopolysaccharide promotes Drp1-dependent mitochondrial fission and associated inflammatory responses in macrophages. Immunology and Cell Biology, 98(7), 528-539.
Scopus37 WoS36 Europe PMC232019 Okada, T., Jayasinghe, R. M., Eckermann, P., Watson-Haigh, N. S., Warner, P., Hendrikse, Y., . . . Whitford, R. (2019). Effects of Rht-B1 and Ppd-D1 loci on pollinator traits in wheat. Theoretical and Applied Genetics, 132(7), 1965-1979.
Scopus20 WoS19 Europe PMC82019 Pallotta, M. A., Warner, P., Kouidri, A., Tucker, E. J., Baes, M., Suchecki, R., . . . Whitford, R. (2019). Wheat ms5 male-sterility is induced by recessive homoeologous A and D genome non-specific lipid transfer proteins. Plant Journal, 99(4), 673-685.
Scopus28 WoS26 Europe PMC112018 Kouidri, A., Baumann, U., Okada, T., Baes, M., Tucker, E., & Whitford, R. (2018). Wheat TaMs1 is a glycosylphosphatidylinositol-anchored lipid transfer protein necessary for pollen development. BMC Plant Biology, 18(1), 13 pages.
Scopus16 WoS16 Europe PMC82018 Okada, T., Jayasinghe, R., Nansamba, M., Baes, M., Warner, P., Kouidri, A., . . . Baumann, U. (2018). Unfertilized ovary pushes wheat flower open for cross-pollination. Journal of Experimental Botany, 69(3), 399-412.
Scopus25 WoS22 Europe PMC162017 Tucker, E., Baumann, U., Kouidri, A., Suchecki, R., Baes, M., Garcia, M., . . . Whitford, R. (2017). Molecular identification of the wheat male fertility gene Ms1 and its prospects for hybrid breeding. Nature Communications, 8(1), 869-1-869-10.
Scopus76 WoS70 Europe PMC342015 Shirasawa, K., Hand, M., Henderson, S., Okada, T., Johnson, S., Taylor, J., . . . Koltunow, A. (2015). A reference genetic linkage map of apomictic Hieracium species based on expressed markers derived from developing ovule transcripts. Annals of Botany, 115(4), 567-580.
Scopus7 WoS6 Europe PMC52015 Nguyen, V., Fleury, D., Timmins, A., Laga, H., Hayden, M., Mather, D., & Okada, T. (2015). Addition of rye chromosome 4R to wheat increases anther length and pollen grain number. Theoretical and Applied Genetics, 128(5), 953-964.
Scopus32 WoS33 Europe PMC152014 Kotani, Y., Henderson, S., Suzuki, G., Johnson, S., Okada, T., Siddons, H., . . . Koltunow, A. (2014). The LOSS OF APOMEIOSIS (LOA) locus in Hieracium praealtum can function independently of the associated large-scale repetitive chromosomal structure. New Phytologist, 201(3), 973-981.
Scopus32 WoS30 Europe PMC192013 Whitford, R., Fleury, D., Reif, J., Garcia, M., Okada, T., Korzun, V., & Langridge, P. (2013). Hybrid breeding in wheat: technologies to improve hybrid wheat seed production. Journal of Experimental Botany, 64(18), 5411-5428.
Scopus180 WoS174 Europe PMC942013 Okada, T., Hu, Y., Tucker, M., Taylor, J., Johnson, S., Spriggs, A., . . . Koltunow, A. (2013). Enlarging cells initiating apomixis in Hieracium praealtum transition to an embryo sac program prior to entering mitosis. Plant Physiology, 163(1), 216-231.
Scopus55 WoS52 Europe PMC392013 Garmatiuk, T., Swoboda, I., Twardosz-Kropfmüller, A., Dall’Antonia, F., Keller, W., Singh, M. B., . . . Valenta, R. (2013). Characterization of mutants of a highly cross-reactive calcium-binding protein from Brassica pollen for allergen-specific immunotherapy. Immunobiology, 218(9), 1155-1165.
Scopus6 WoS5 Europe PMC32012 Tucker, M., Okada, T., Johnson, S., Takaiwa, F., & Koltunow, A. (2012). Sporophytic ovule tissues modulate the initiation and progression of apomixis in Hieracium. Journal of Experimental Biology, 63(8), 3229-3241.
Scopus36 WoS33 Europe PMC262012 Tucker, M., Okada, T., Hu, Y., Scholefield, A., Taylor, J., & Koltunow, A. (2012). Somatic small RNA pathways promote the mitotic events of megagametogenesis during female reproductive development in arabidopsis. Development, 139(8), 1399-1404.
Scopus118 WoS113 Europe PMC792011 Okada, T., Ito, K., Johnson, S., Oelkers, K., Suzuki, G., Houben, A., . . . Koltunow, A. (2011). Chromosomes carrying meiotic avoidance loci in three apomictic eudicot Hieracium subgenus Pilosella species share structural features with two monocot apomicts. Plant Physiology, 157(3), 1327-1341.
Scopus40 WoS38 Europe PMC302011 Koltunow, A., Johnson, S., & Okada, T. (2011). Apomixis in hawkweed: Mendel's experimental nemesis. Journal of Experimental Botany, 62(5), 1699-1707.
Scopus25 WoS22 Europe PMC222011 Koltunow, A. M., Johnson, S. D., Rodrigues, J. C., Okada, T., Hu, Y., Tsuchiya, T., . . . Bicknell, R. A. (2011). Sexual reproduction is the default mode in apomictic Hieracium subgenus Pilosella, in which two dominant loci function to enable apomixis. The Plant Journal, 66(5), 890-902.
Scopus83 WoS80 Europe PMC512010 Rodrigues, J. C., Okada, T., Johnson, S. D., & Koltunow, A. M. (2010). A multicopy suppressor of IRA1 (MSI1) homologue is not associated with the switch to autonomous seed development in apomictic (asexual) Hieracium plants. Plant Science, 179(6), 590-597.
Scopus11 WoS9 Europe PMC52008 Okada, T., & Ozawa, K. (2008). Vector-producing tumor-tracking multipotent mesenchymal stromal cells for suicide cancer gene therapy. FRONTIERS IN BIOSCIENCE-LANDMARK, 13(13), 1887-1891.
WoS15 Europe PMC92008 Liu, Y., Okada, T., Shimazaki, K., Sheykholeslami, K., Nomoto, T., Muramatsu, S. -I., . . . Ozawa, K. (2008). Protection against aminoglycoside-induced ototoxicity by regulated AAV vector-mediated GDNF gene transfer into the cochlea. MOLECULAR THERAPY, 16(3), 474-480.
WoS32 Europe PMC52007 Kobayashi, M., Okada, T., Murakami, T., Ozawa, K., Kobayashi, E., & Morita, T. (2007). Tissue-targeted in vivo gene transfer coupled with histone deacetylase inhibitor depsipeptide (FK228) enhances adenoviral infection in rat renal cancer allograft model systems. UROLOGY, 70(6), 7 pages.
WoS7 Europe PMC42007 Ito, T., Okada, T., Miyashita, H., Nomoto, T., Nonaka-Sarukawa, M., Uchibori, R., . . . Ozawa, K. (2007). Interleukin-10 expression mediated by an adeno-associated virus vector prevents monocrotaline-induced pulmonary arterial hypertension in rats. CIRCULATION RESEARCH, 101(7), 734-741.
WoS89 Europe PMC712007 Shiraishi, J., Kohno, Y., Sawada, T., Nishizawa, S., Arihara, M., Hadase, M., . . . Matsubara, H. (2007). In-hospital outcomes of primary percutaneous coronary interventions performed at hospitals with and without on-site coronary artery bypass graft surgery. CIRCULATION JOURNAL, 71(8), 1208-1212.
WoS17 Europe PMC162007 Ito, T., Okada, T., Mimuro, J., Miyashita, H., Uchibori, R., Urabe, M., . . . Ozawa, K. (2007). Adenoassociated virus-mediated prostacyclin synthase expression prevents pulmonary arterial hypertension in rats. HYPERTENSION, 50(3), 531-536.
WoS20 Europe PMC182007 Sato, T., Muto, I., Hasegawa, M., Aono, T., Okada, T., Hasegawa, J., . . . Hatakeyama, K. (2007). Breast signet-ring cell lobular carcinoma presenting with duodenal obstruction and acute pancreatitis. ASIAN JOURNAL OF SURGERY, 30(3), 220-223.
WoS12 Europe PMC82007 Liu, Y., Okada, T., Nomoto, T., Ke, X., Kume, A., Ozawa, K., & Xiao, S. (2007). Promoter effects of adeno-associated viral vector for transgene expression in the cochlea in vivo. EXPERIMENTAL AND MOLECULAR MEDICINE, 39(2), 170-175.
WoS39 Europe PMC332007 Nakata, M., Okada, T., Ozawa, K., & Yada, T. (2007). Resistin induces insulin resistance in pancreatic islets to impair glucose-induced insulin release. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 353(4), 1046-1051.
WoS55 Europe PMC362007 Ideno, J., Mizukami, H., Kakehashi, A., Saito, Y., Okada, T., Urabe, M., . . . Ozawa, K. (2007). Prevention of diabetic retinopathy by intraocular soluble flt-1 gene transfer in a spontaneously diabetic rat model. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 19(1), 75-79.
WoS45 Europe PMC322007 Okada, T., Singh, M. B., & Bhalla, P. L. (2007). Transcriptome profiling of Lilium longiflorum generative cells by cDNA microarray. Plant Cell Reports, 26(7), 1045-1052.
Scopus38 WoS36 Europe PMC282007 Okada, T., Catanach, A. S., Johnson, S. D., Bicknell, R. A., & Koltunow, A. M. (2007). An Hieracium mutant, loss of apomeiosis 1 (loa1) is defective in the initiation of apomixis. Sexual Plant Reproduction, 20(4), 199-211.
Scopus21 WoS19 Europe PMC72006 Okada, T., Singh, M., & Bhalla, P. (2006). Histone H3 variants in male gametic cells of lily and H3 methylation in mature pollen. Plant Molecular Biology, 62(4), 503-512.
Scopus37 WoS37 Europe PMC262006 Okada, T., Bhalla, P. L., & Singh, M. B. (2006). Expressed sequence tag analysis of Lilium longiflorum generative cells. Plant and Cell Physiology, 47(6), 698-705.
Scopus48 WoS43 Europe PMC332006 Ishiwata, A., Mimuro, J., Kashiwakura, Y., Niimura, M., Takano, K., Ohmori, T., . . . Sakata, Y. (2006). Phenotype correction of hemophilia A mice with adeno-associated virus vectors carrying the B domain-deleted canine factor VIII gene. THROMBOSIS RESEARCH, 118(5), 627-635.
WoS17 Europe PMC152006 Dieng, H., Boots, M., Tamori, N., Higashihara, J., Okada, T., Kato, K., & Eshita, Y. (2006). Some technical and ecological determinants of hatchability in Aedes albopictus, a potential candidate for transposon-mediated transgenesis. JOURNAL OF THE AMERICAN MOSQUITO CONTROL ASSOCIATION, 22(3), 382-389.
WoS12 Europe PMC72006 Mizukami, H., Mimuro, J., Ogura, T., Okada, T., Urabe, M., Kume, A., . . . Ozawa, K. (2006). Adipose tissue as a novel target for in vivo gene transfer by adeno-associated viral vectors. HUMAN GENE THERAPY, 17(9), 921-928.
WoS26 Europe PMC232006 Ogura, T., Mizukami, H., Mimuro, J., Madoiwa, S., Okada, T., Matsushita, T., . . . Ozawa, K. (2006). Utility of intraperitoneal administration as a route of AAV serotype 5 vector-mediated neonatal gene transfer. JOURNAL OF GENE MEDICINE, 8(8), 990-997.
WoS18 Europe PMC132005 Okada, T., Endo, M., Singh, M., & Bhalla, P. (2005). Analysis of the histone H3 gene family in Arabidopsis and identification of the male-gamete-specific variant AtMGH3. Plant Journal, 44(4), 557-568.
Scopus174 WoS165 Europe PMC1162005 Okada, T., Bhalla, P., & Singh, M. (2005). Transcriptional activity of male gamete-specific histone gcH3 promoter in sperm cells of Lilium longiflorum. Plant and Cell Physiology, 46(5), 797-802.
Scopus25 WoS27 Europe PMC182003 Okada, A., Okada, T., Ide, T., Itoh, M., Tanaka, K., Takaiwa, F., & Toriyama, K. (2003). Accumulation of Japanese cedar pollen allergen, Cry j 1, in the protein body I of transgenic rice seeds using the promoter and signal sequence of glutelin GluB-1 gene. Molecular Breeding, 12(1), 61-70.
Scopus10 WoS6 Europe PMC42001 Okada, T., & Toriyama, K. (2001). Pollen vegetative cell-specific expression of Bra r 1: Useful tool for observation of the vegetative nucleus and identification of transgenic pollen by nuclear-targeted GFP. Sexual Plant Reproduction, 13(6), 301-307.
Scopus6 WoS5 Europe PMC12000 Okada, T., Sasaki, Y., Ohta, R., Onozuka, N., & Toriyama, K. (2000). Expression of Bra r 1 gene in transgenic tobacco and Bra r 1 promoter activity in pollen of various plant species. Plant and Cell Physiology, 41(6), 757-766.
Scopus14 WoS14 Europe PMC101999 Okada, T., Zhang, Z., Russell, S. D., & Toriyama, K. (1999). Localization of the Ca<sup>2+</sup>-binding protein, Bra r 1, in anthers and pollen tubes. Plant and Cell Physiology, 40(12), 1243-1252.
Scopus24 WoS23 Europe PMC121998 Okada, T., Swoboda, I., Bhalla, P. L., Toriyama, K., & Singh, M. B. (1998). Engineering of hypoallergenic mutants of the Brassica pollen allergen, Bra r 1, for immunotherapy. FEBS Letters, 434(3), 255-260.
Scopus55 WoS46 Europe PMC341998 Toriyama, K., Hanaoka, K., Okada, T., & Watanabe, M. (1998). Molecular cloning of a cDNA encoding a pollen extracellular protein as a potential source of a pollen allergen in Brassica rapa. FEBS Letters, 424(3), 234-238.
Scopus40 WoS37 Europe PMC221997 Toriyama, K., Okada, T., Hanaoka, K., Watanabe, M., & Hinata, K. (1997). Characterization of genes encoding pollen allergen and pollen coat protein in Brassica rapa.. PLANT PHYSIOLOGY, 114(3), 1243. 1995 Toriyama, K., Okada, T., Watanabe, M., Ide, T., Ashida, T., Xu, H., & Singh, M. (1995). A cDNA clone encoding an IgE-binding protein from Brassica anther has significant sequence similarity to Ca²⁺-binding proteins. Plant Molecular Biology, 29(6), 1157-1165.
Scopus46 WoS43 Europe PMC23 -
Book Chapters
Year Citation 2019 Okada, T., & Whitford, R. (2019). Hybrid wheat and abiotic stress. In V. R. Rajpal, D. Sehgal, A. Kumar, & S. N. Raina (Eds.), Genomics Assisted Breeding of Crops for Abiotic Stress Tolerance, Vol. II (Vol. 2, pp. 211-224). Cham, Switzerland: Springer.
2010 Koltunow, A. M., Okada, T., & Bicknell, R. A. (2010). Apomixis. In D. Simberloff, & M. Rejmanek (Eds.), Encyclopedia of Biological Invasions (pp. 24-27). Berkeley: Univ of California Press. -
Conference Papers
Year Citation 2008 Uchibori, R., Okada, T., Ito, T., Matsushita, T., Urabe, M., Mizukami, H., . . . Ozawa, K. (2008). Tumor tracking and therapeutic gene amplification by using retroviral vector-producing mesenchymal stem cells for reinforcement of suicide cancer gene therapy. In JOURNAL OF GENE MEDICINE Vol. 10 (pp. 478-479). Nagoya, JAPAN: JOHN WILEY & SONS LTD. 2008 Shin, J. -H., Ohshima, S., Nishiyama, A., Yuasa, K., Nakai, H., Okada, T., & Takeda, S. (2008). Efficient systemic delivery of RAAV8 into dystrophic animals by subcutaneous injection. In JOURNAL OF GENE MEDICINE Vol. 10 (pp. 449). Nagoya, JAPAN: JOHN WILEY & SONS LTD. 2008 Nishiyama, A., Ampong, B. N., Shin, J. -H., Nakai, H., Okada, T., & Takeda, S. (2008). Safe and extensive RAAV8-mediated alpha-SG transduction of the limb-girdle muscular dystrophy type 2D model mice. In JOURNAL OF GENE MEDICINE Vol. 10 (pp. 448). Nagoya, JAPAN: JOHN WILEY & SONS LTD. 2008 Kume, A., Matsushita, T., Mizukami, H., Urabe, M., Okada, T., & Ozawal, K. (2008). Efficient and stable liver transduction by a self-complementary adeno-associated virus vector for phenylketonuria gene therapy. In JOURNAL OF GENE MEDICINE Vol. 10 (pp. 443-444). Nagoya, JAPAN: JOHN WILEY & SONS LTD. 2007 Uchibori, R., Okada, T., Ito, T., Urabe, M., Mizukami, H., Kume, A., & Ozawa, K. (2007). Retroviral vector-producing mesenchymal stem cells for tumor tracking and therapeutic gene amplification in suicide cancer gene therapy. In BLOOD Vol. 110 (pp. 570A). Atlanta, GA: AMER SOC HEMATOLOGY. 2007 Nishiyama, A., Ampong, B. N., Shin, J. -H., Nakai, H., Okada, T., & Takeda, S. (2007). Extensive alpha-sarcoglycan expression by intramuscular and intravenous administration of rAAV type 8. In HUMAN GENE THERAPY Vol. 18 (pp. 1029). Rotterdam, NETHERLANDS: MARY ANN LIEBERT INC. 2007 Ohshima, S., Shin, J. -H., Nishiyama, A., Yuasa, K., Nakamura, A., Nakai, H., . . . Takeda, S. (2007). Transduction profiles and immune response in the dystrophic dogs with rAAV serotype 8. In HUMAN GENE THERAPY Vol. 18 (pp. 984-985). Rotterdam, NETHERLANDS: MARY ANN LIEBERT INC. 2006 Ito, T., Okada, T., Nonaka-Sarukawa, M., Yamamoto, K., Ozawa, K., & Shimada, K. (2006). Interleukin-10-induced adiponectin production in adipogenic visceral stromal-vascular cells. In CIRCULATION Vol. 114 (pp. 307-308). Chicago, IL: LIPPINCOTT WILLIAMS & WILKINS. 2006 Kume, A., Ogura, T., Matsushita, T., Mizukami, H., Urabe, M., Okada, T., & Ozawa, K. (2006). Complete normalization of hyperphenylalaninemia in female Pah(enu2) mouse by a self-complementary adeno-associated virus vector. In JOURNAL OF GENE MEDICINE Vol. 8 (pp. 1444-1445). Nippon Med Sch, Tokyo, JAPAN: JOHN WILEY & SONS LTD. 2006 Uchibori, R., Okada, T., Onodera, M., Matsushita, T., Urabe, M., Mizukami, H., . . . Ozawa, K. (2006). Development of the vector-producing tumor-tracking cells for improved suicide cancer gene therapy. In JOURNAL OF GENE MEDICINE Vol. 8 (pp. 1471-1472). Nippon Med Sch, Tokyo, JAPAN: JOHN WILEY & SONS LTD. 2006 Okada, T., Uchibori, R., Iwata-Okada, M., Nonaka-Sarukawa, M., Ito, T., Liu, Y., . . . Ozawa, K. (2006). The histone-associated chromatin form is involved in the improved rAAV-mediated transduction by HDAC inhibitor. In JOURNAL OF GENE MEDICINE Vol. 8 (pp. 1471). Nippon Med Sch, Tokyo, JAPAN: JOHN WILEY & SONS LTD. 2006 Sarukawa, M., Okada, T., Yoshioka, T., Ito, T., Nomoto, T., Mizukami, H., . . . Ozawa, K. (2006). AAV vector-mediated interleukin-10 expression upregulates HO-1 to prevent hypertension in Dahl-salt-sensitive rats. In JOURNAL OF GENE MEDICINE Vol. 8 (pp. 1464). Nippon Med Sch, Tokyo, JAPAN: JOHN WILEY & SONS LTD. 2006 Ito, T., Okada, T., Mimuro, J., Miyashita, H., Nonaka-Sarukawa, M., Mizukami, H., . . . Ozawa, K. (2006). Prevention of rat pulmonary hypertension by adeno-associated virus vector-mediated prostacyclin synthase expression. In JOURNAL OF GENE MEDICINE Vol. 8 (pp. 1463-1464). Nippon Med Sch, Tokyo, JAPAN: JOHN WILEY & SONS LTD. 2006 Mizukami, H., Mimuro, J., Ishiwata, A., Ono, F., Matsushita, T., Okada, T., . . . Ozawa, K. (2006). Utility of AAV serotype-based vectors in mice and non-human primates. In JOURNAL OF GENE MEDICINE Vol. 8 (pp. 1460). Nippon Med Sch, Tokyo, JAPAN: JOHN WILEY & SONS LTD. 2006 Kume, A., Matsuda, M., Ueda, Y., Matsushita, T., Mizukami, H., Urabe, M., . . . Ozawa, K. (2006). Evaluation of erythropoietin-responsive selective cell amplifier in a mouse model of X-linked chronic granulomatous disease. In JOURNAL OF GENE MEDICINE Vol. 8 (pp. 1460-1461). Nippon Med Sch, Tokyo, JAPAN: JOHN WILEY & SONS LTD. 2006 Xiao, W. -Z., Matsushita, T., Nara, Y., Takino, N., Nishida, H., Kodera, M., . . . Muramatsu, S. -I. (2006). Efficient transduction of oligodendrocytes by AAV8 vectors. In JOURNAL OF GENE MEDICINE Vol. 8 (pp. 1448). Nippon Med Sch, Tokyo, JAPAN: JOHN WILEY & SONS LTD. 2006 Sarukawa, M., Okada, T., Yoshioka, T., Ito, T., Nomoto, T., Shimpo, M., . . . Shimada, K. (2006). Systemic interleukin-10 expression prevents hypertension and heart failure through upregulation of heme oxygenase-1 in dahl salt-sensitive rats.. In CIRCULATION Vol. 114 (pp. 205). Chicago, IL: LIPPINCOTT WILLIAMS & WILKINS. 2006 Ito, T., Okada, T., Miyashita, H., Nonaka-Sarukawa, M., Yamamoto, K., Ozawa, K., & Shimada, K. (2006). Prevention of monocrotaline-induced pulmonary arterial hypertension by an intramuscular injection of an adeno-associated virus vector expressing prostacyclin synthase. In CIRCULATION Vol. 114 (pp. 82). Chicago, IL: LIPPINCOTT WILLIAMS & WILKINS. 2006 Sarukawa, M., Okada, T., Yoshioka, T., Ito, T., Nomoto, T., Mizukami, H., . . . Ozawa, K. (2006). Prevention of Cardiac Remodeling and Heart Failure in Dahl-Salt Sensitive Rats by AAV Vector-Mediated Interleukin-10 Expression. In MOLECULAR THERAPY Vol. 13 (pp. S12). NATURE PUBLISHING GROUP.
2006 Okada, T., Uchibori, R., Iwata-Okada, M., Nonaka-Sarukawa, M., Ito, T., Mizukami, H., . . . Ozawa, K. (2006). Episomal AAV Vector Genome in the Histone-Associated Chromatin Form Is Capable of Superior Transcription with HDAC Inhibitor. In MOLECULAR THERAPY Vol. 13 (pp. S45). NATURE PUBLISHING GROUP.
2006 Ito, T., Okada, T., Mimuro, J., Miyashita, H., Nonaka-Sarukawa, M., Mizukami, H., . . . Ozawa, K. (2006). In Vivo Gene Transfer of Prostacyclin Synthase by Using AAV Vector Prevents Monocrotaline-Induced Pulmonary Hypertension and Pulmonary Vasoconstriction in Rats. In MOLECULAR THERAPY Vol. 13 (pp. S333). NATURE PUBLISHING GROUP.
2006 Kume, A., Ogura, T., Matsushita, T., Mizukami, H., Urabe, M., Okada, T., & Ozawa, K. (2006). Sustained Correction of Hyperphenylalaninemia in Female Pah(enu2) Mouse by a Self-Complementary Adeno-Associated Virus Vector. In MOLECULAR THERAPY Vol. 13 (pp. S87). NATURE PUBLISHING GROUP.
2006 Nobuyoshi, M., Kume, A., Matsushita, T., Mizukami, H., Okada, T., Urabe, M., . . . Ozawa, K. (2006). AAV Vector-Mediated Msx1 Gene Transfer Induces Hematopoietic Stem/Progenitor Cells in Skeletal Muscle. In MOLECULAR THERAPY Vol. 13 (pp. S131). NATURE PUBLISHING GROUP.
2006 Mizukami, H., Mimuro, J., Ishiwata, A., Ono, F., Matsushita, T., Okada, T., . . . Ozawa, K. (2006). AAV8-Mediated Transgene Expression in Mice and Non-Human Primates. In MOLECULAR THERAPY Vol. 13 (pp. S3). NATURE PUBLISHING GROUP.
2006 Ito, T., Okada, T., Miyashita, H., Nonaka-Sarukawa, M., Yamamoto, K., Ozawa, K., & Shimada, K. (2006). Mechanisms underlying interleukin-10-mediated anti-remodeling effects on monocrotaline-induced pulmonary arterial hypertension. In CIRCULATION Vol. 114 (pp. 327). LIPPINCOTT WILLIAMS & WILKINS. 2005 Iwai, K., Okada, T., Nakazato, K., Fujimoto, H., Yamamoto, Y., & Nakajima, H. (2005). Trunk Muscle Strength And Muscle Cross-sectional Areas In Collegiate Wrestlers And Judo Players. In MEDICINE AND SCIENCE IN SPORTS AND EXERCISE Vol. 37 (pp. S354-S355). LIPPINCOTT WILLIAMS & WILKINS.
2005 Okada, T., Iwai, K., Nakazato, K., Tanabe, M., Irie, K., & Nakajima, H. (2005). Low Back Pain And Lumbar Radiological Abnormalities In Collegiate Judo Players. In MEDICINE AND SCIENCE IN SPORTS AND EXERCISE Vol. 37 (pp. S144-S145). LIPPINCOTT WILLIAMS & WILKINS.
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Conference Items
Year Citation 2013 Tucker, E., Okada, T., Warner, P., Manning, S., Baes, M., Kouidri, A., . . . Whitford, R. (2013). Towards the development of a fertility control system for hybrid wheat breeding. Poster session presented at the meeting of Wheat Breeders Assembly. Brisbane, Australia: http://wheatbreedingassembly.com.au/. 2013 Okada, T., Jayasinghe, R., Langridge, P., & Fleury, D. (2013). Screening of a Triticeae germplasm collection for floral architecture traits that enhance out-crossing in wheat for hybrid seed production. Poster session presented at the meeting of The 12th International Wheat Genetics Symposium. Yokohama, Japan.
| Date | Project/ No. | Investigators | Funding Body | Amount |
|---|---|---|---|---|
| 2015 | WRI Equipment Grant | Okada T, Mayo G, | Waite Research Institute | $31K |
| 2013 | WRI Equipment Grant | Mayo G, Okada T, | Waite Research Institute | $42K |
| 2010 | Transformation Technology | Okada T | CSIRO Plant Industry | $23K |
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