Dr Susan Woods

• Appointments

  Date	Position	Institution name
  2022 - ongoing	A/Prof	University of Adelaide
  2019 - 2021	Beat Cancer SA Fellow & Group Leader	University of Adelaide
  2018 - ongoing	Senior Research Fellow	SAHMRI
  2015 - 2018	Associate Research Fellow	SAHMRI
  2015 - ongoing	Senior Research Fellow	University of Adelaide

• Awards and Achievements

  Date	Type	Title	Institution Name	Country	Amount
  2019	Award	Community Engagement Award SAHMRI	SAHMRI	Australia	-
  2019	Achievement	Pitch Perfect Finalist SAHMRI	SAHMRI	Australia	-
  2018	Award	Best Mid-Career Researcher Award SAHMRI	SAHMRI	Australia	-
  2017	Award	Poster of Merit Finalist Gastroenterological Society of Australia,	GESA	Australia	-
  2017	Award	Faculty of Health Sciences Research Travel Award	University of Adelaide	Australia	-
  2016	Award	Tall Poppy Science Award (SA)	Australian Institute of Policy & Science	Australia	-
  2016	Award	Faculty of Health Sciences Dependant Travel Award	university of adelaide	Australia	-
  2015	Award	University of Adelaide Women’s Research Excellence award	the university of Adelaide	Australia	-
  2011	Award	ASMR Best Senior Researcher Award (QLD)	Australian Society for Medical Research (QLD)	Australia	-
  1999	Award	Adelaide National Research Scholarship	the university of Adelaide	Australia	-

• Education

  Date	Institution name	Country	Title
  	University of Adelaide	Australia	PhD

• Postgraduate Training

  Date	Title	Institution	Country
  	Postdoctoral Fellow	University of California, San Francisco	United States
  	Research Fellow	QIMR Berghofer Medical Research Institute	Australia

• Research Interests

  Cancer Cell Biology Cancer Genetics Cancer Therapy Gastroenterology and Hepatology Cancer Biology and Clinical Oncology

• Journals

  Year	Citation
  2024	Radford, G. A., Vrbanac, L., de Nys, R. T., Worthley, D. L., Wright, J. A., Hasty, J., & Woods, S. L. (2024). Towards Understanding Tumour Colonisation by Probiotic Bacterium E. coli Nissle 1917. Cancers, 16(17), 18 pages. DOI
  2024	Arai, J., Hayakawa, Y., Tateno, H., Murakami, K., Hayashi, T., Hata, M., . . . Fujishiro, M. (2024). Impaired Glycosylation of Gastric Mucins Drives Gastric Tumorigenesis and Serves as a Novel Therapeutic Target. Gastroenterology, 167(3), 505-521.e19. DOI Scopus1
  2024	Nguyen, T. P. M., Woods, S. L., Secombe, K. R., Tang, S., Elz, A. S., Ayton, S., . . . Bowen, J. M. (2024). Ferroptosis – a potential feature underlying neratinib-induced colonic epithelial injury. Cancer Chemotherapy and Pharmacology, 94(4), 493-505. DOI
  2024	Kobayashi, H., Iida, T., Ochiai, Y., Malagola, E., Zhi, X., White, R. A., . . . Wang, T. C. (2024). Neuro-mesenchymal interaction mediated by a β2 adrenergic-nerve growth factor feedforward loop promotes colorectal cancer progression.. Cancer discovery. DOI
  2024	Li, C. M. Y., Tomita, Y., Dhakal, B., Tin, T., Li, R., Wright, J. A., . . . Fenix, K. (2024). Generation and assessment of cytokine-induced killer cells for the treatment of colorectal cancer liver metastases. Cancer Immunology Immunotherapy, 73(1), 6-1-6-16. DOI
  2024	Gurbatri, C. R., Radford, G. A., Vrbanac, L., Im, J., Thomas, E. M., Coker, C., . . . Danino, T. (2024). Engineering tumor-colonizing E. coli Nissle 1917 for detection and treatment of colorectal neoplasia. Nature Communications, 15(1), 646-1-646-13. DOI Scopus14 Europe PMC7
  2023	Hocking, A. J., Thomas, E. M., Prabhakaran, S., Jolley, A., Woods, S. L., Soeberg, M. J., & Klebe, S. (2023). Molecular Characterization of Testicular Mesothelioma and the Role of Asbestos as a Causative Factor. Archives of Pathology and Laboratory Medicine, 147(12), 1446-1450. DOI Scopus6 WoS1
  2023	Gurbatri, C. R., Radford, G., Vrbanac, L., Coker, C., Im, J. -W., Taylor, S. R., . . . Danino, T. (2023). Colorectal cancer detection and treatment with engineered probiotics.. bioRxiv. DOI
  2023	Ng, J. Q., Jafarov, T. H., Little, C. B., Wang, T., Ali, A., Ma, Y., . . . Mukherjee, S. (2023). Loss of Grem1-articular cartilage progenitor cells causes osteoarthritis.. bioRxiv. DOI
  2023	Cooper, R. M., Wright, J. A., Ng, J. Q., Goyne, J. M., Suzuki, N., Lee, Y. K., . . . Hasty, J. (2023). Engineered bacteria detect tumor DNA. Science, 381(6658), 682-686. DOI Scopus19 WoS5 Europe PMC9
  2023	Thomas, E. M., Wright, J. A., Blake, S. J., Page, A. J., Worthley, D. L., & Woods, S. L. (2023). Advancing translational research for colorectal immuno-oncology. British Journal of Cancer, 129(9), 1442-1450. DOI Scopus4 WoS1 Europe PMC4
  2023	Niikura, R., Hayakawa, Y., Nagata, N., Miyoshi-Akiayama, T., Miyabayashi, K., Tsuboi, M., . . . Fujishiro, M. (2023). Non-Helicobacter pylori Gastric Microbiome Modulates Prooncogenic Responses and Is Associated With Gastric Cancer Risk. Gastro Hep Advances, 2(5), 684-700. DOI Scopus8 Europe PMC2
  2023	Ng, J. Q., Jafarov, T. H., Little, C. B., Wang, T., Ali, A. M., Ma, Y., . . . Mukherjee, S. (2023). Loss of Grem1-lineage chondrogenic progenitor cells causes osteoarthritis. Nature Communications, 14(1), 6909-1-6909-14. DOI Scopus3 Europe PMC3
  2022	Kobayashi, H., Gieniec, K. A., Lannagan, T. R., Wang, T., Asai, N., Mizutani, Y., . . . Worthley, D. L. (2022). The origin and contribution of cancer-associated fibroblasts in colorectal carcinogenesis. Gastroenterology, 162(3), 890-906. DOI Scopus83 WoS37 Europe PMC67
  2022	Dhakal, B., Li, C. M. Y., Li, R., Yeo, K., Wright, J. A., Gieniec, K. A., . . . Fenix, K. (2022). The Antianginal Drug Perhexiline Displays Cytotoxicity against Colorectal Cancer Cells In Vitro: A Potential for Drug Repurposing. Cancers, 14(4), 16 pages. DOI Scopus10 WoS7 Europe PMC9
  2022	Vatandoust, S., Wattchow, D., Sposato, L., Michael, M. Z., Leung, J., Gormly, K., . . . Karapetis, C. S. (2022). A longitudinal cohort study of watch and wait in complete clinical responders after chemo-radiotherapy for localised rectal cancer: study protocol. BMC Cancer, 22(1), 13 pages. DOI Scopus4 WoS2 Europe PMC1
  2021	Suzuki, M. I., Suzuki, N., Wang, T., Wright, J. A., Lannagan, T. R., Vrbanac, L., . . . Woods, S. L. (2021). Stromal DLK1 promotes proliferation and inhibits differentiation of the intestinal epithelium during development. American Journal of Physiology: Gastrointestinal and Liver Physiology, 320(4), G506-G520. DOI Scopus5 WoS3 Europe PMC3
  2021	Ichinose, M., Suzuki, N., Wang, T., Wright, J. A., Lannagan, T. R. M., Vrbanac, L., . . . Woods, S. L. (2021). Delineating proinflammatory microenvironmental signals by ex vivo modeling of the immature intestinal stroma. Scientific Reports, 11(1), 7200-1-7200-11. DOI Scopus1 WoS1 Europe PMC1
  2021	Suzuki, M., Suzuki, N., Wang, T., Kobayashi, H., Vrbanac, L., Ng, J. Q., . . . Woods, S. L. (2021). The BMP antagonist Gremlin1 contributes to the development of cortical excitatory neurons, motor balance and fear responses. Development, 148(14), dev195883-1-dev195883-15. DOI Scopus7 WoS4 Europe PMC5
  2021	Kobayashi, H., Gieniec, K. A., Ng, J. Q., Goyne, J., Lannagan, T. R. M., Thomas, E. M., . . . Woods, S. L. (2021). Portal Vein Injection of Colorectal Cancer Organoids to Study the Liver Metastasis Stroma. Journal of Visualized Experiments, 2021(175), e62630-1-e62630-21. DOI Europe PMC1
  2020	Narasimhan, V., Wright, J. A., Churchill, M., Wang, T., Rosati, R., Lannagan, T. R., . . . Woods, S. L. (2020). Medium-throughput drug screening of patient-derived organoids from colorectal peritoneal metastases to direct personalized therapy. Clinical Cancer Research, 26(14), 1-26. DOI Scopus119 WoS79 Europe PMC91
  2020	Kobayashi, H., Gieniec, K. A., Wright, J. A., Wang, T., Asai, N., Mizutani, Y., . . . Woods, S. L. (2020). The Balance of stromal BMP signaling mediated by GREM1 and ISLR drives colorectal carcinogenesis. Gastroenterology, 160(4), 1224-1239. DOI Scopus86 WoS60 Europe PMC72
  2019	Kleeman, S. O., Koelzer, V. H., Jones, H. J., Vazquez, E. G., Davis, H., East, J. E., . . . Leedham, S. J. (2019). Exploiting differential Wnt target gene expression to generate a molecular biomarker for colorectal cancer stratification. Gut, 69(6), 1092-1103. DOI Scopus53 WoS42 Europe PMC45
  2019	Ng, J., Little, C. B., Woods, S., Whittle, S., Lee, F. Y., Gronthos, S., . . . Worthley, D. L. (2019). Stem cell directed therapies for osteoarthritis: the promise and the practice: concise review. Stem Cells, 38(4), 477-486. DOI Scopus20 WoS15 Europe PMC9
  2019	Lannagan, T. R. M., Lee, Y. K., Wang, T., Roper, J., Bettington, M. L., Fennell, L., . . . Woods, S. L. (2019). Genetic editing of colonic organoids provides a molecularly distinct and orthotopic preclinical model of serrated carcinogenesis. Gut, 68(4), 684-692. DOI Scopus88 WoS63 Europe PMC68
  2019	Suzuki, N., Niikura, R., Ihara, S., Hikiba, Y., Kinoshita, H., Higashishima, N., . . . Koike, K. (2019). Alpha-Blockers as colorectal cancer chemopreventive: findings from a case-control study, human cell cultures, and in vivo preclinical testing. Cancer Prevention Research, 12(3), 185-194. DOI Scopus4 WoS4 Europe PMC5
  2019	Kobayashi, H., Enomoto, A., Woods, S. L., Burt, A. D., Takahashi, M., & Worthley, D. L. (2019). Cancer-associated fibroblasts in gastrointestinal cancer. Nature Reviews Gastroenterology and Hepatology, 16(5), 282-295. DOI Scopus390 WoS285 Europe PMC292
  2019	Gieniec, K. A., Butler, L. M., Worthley, D. L., & Woods, S. L. (2019). Cancer-associated fibroblasts—heroes or villains?. British Journal of Cancer, 121(4), 293-302. DOI Scopus163 WoS127 Europe PMC118
  2019	Mizutani, Y., Kobayashi, H., Iida, T., Asai, N., Masamune, A., Hara, A., . . . Enomoto, A. (2019). Meflin-positive cancer-associated fibroblasts inhibit pancreatic carcinogenesis.. Cancer research, 79(20), 5367-5381. DOI Scopus209 WoS154 Europe PMC142
  2018	Bond, C., Liu, C., Kawamata, F., McKeone, D., Fernando, W., Jamieson, S., . . . Whitehall, V. (2018). Oncogenic BRAF mutation induces DNA methylation changes in a murine model for human serrated colorectal neoplasia. Epigenetics, 13(1), 40-48. DOI Scopus48 WoS37 Europe PMC28
  2016	Li, J., Woods, S., Healey, S., Beesley, J., Chen, X., Lee, J., . . . Schrader, K. (2016). Point mutations in Exon 1B of APC reveal gastric adenocarcinoma and proximal polyposis of the stomach as a familial adenomatous polyposis variant. American Journal of Human Genetics, 98(5), 830-842. DOI Scopus178 WoS122 Europe PMC95
  2014	Aoude, L., Pritchard, A., Robles-Espinoza, C., Wadt, K., Harland, M., Choi, J., . . . Hayward, N. (2014). Nonsense mutations in the shelterin complex genes ACD and TERF2IP in familial melanoma. JNCI Journal of the National Cancer Institute, 107(2), dju408-1-dju408-7. DOI Scopus142 WoS118 Europe PMC90
  2013	Hacker, E., Nagore, E., Cerroni, L., Woods, S., Hayward, N., Chapman, B., . . . Whiteman, D. (2013). NRAS and BRAF mutations in cutaneous melanoma and the association with MC1R genotype: findings from Spanish and Austrian populations. Journal of Investigative Dermatology, 133(4), 1027-1033. DOI Scopus36 WoS31 Europe PMC22
  2012	Stark, M., Woods, S., Gartside, M., Bonazzi, V., Dutton-Regester, K., Aoude, L., . . . Hayward, N. (2012). Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing. Nature Genetics, 44(2), 165-169. DOI Scopus160 WoS143 Europe PMC123
  2011	Woods, S., & Bishop, J. (2011). A new transgenic mouse line for tetracycline inducible transgene expression in mature melanocytes and the melanocyte stem cells using the Dopachrome tautomerase promoter. Transgenic Research, 20(2), 421-428. DOI Scopus9 WoS8 Europe PMC6
  2011	Boyle, G. M., Woods, S. L., Bonazzi, V. F., Stark, M. S., Hacker, E., Aoude, L. G., . . . Hayward, N. K. (2011). Melanoma cell invasiveness is regulated by miR-211 suppression of the BRN2 transcription factor. Pigment Cell and Melanoma Research, 24(3), 525-537. DOI Scopus147 WoS140 Europe PMC113
  2011	Yokoyama, S., Woods, S., Boyle, G., Aoude, L., MacGregor, S., Zismann, V., . . . Brown, K. (2011). A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma. Nature, 480(7375), 99-U266. DOI Scopus375 WoS315 Europe PMC261
  2010	Swarbrick, A., Woods, S. L., Shaw, A., Balakrishnan, A., Phua, Y., Nguyen, A., . . . Goga, A. (2010). MiR-380-5p represses p53 to control cellular survival and is associated with poor outcome in MYCN-amplified neuroblastoma. Nature Medicine, 16(10), 1134-1140. DOI Scopus174 WoS156 Europe PMC132
  2008	Woods, S., Farrall, A., Procko, C., & Whitelaw, M. (2008). The bHLH/Per-Arnt-Sim transcription factor SIM2 regulates muscle transcript myomesin2 via a novel, non-canonical E-box sequence. Nucleic Acids Research, 36(11), 3716-3727. DOI Scopus16 WoS14 Europe PMC11
  2002	Woods, S., & Whitelaw, M. (2002). Differential activities of murine single minded 1 (SIM1) and SIM2 on a hypoxic response element - Cross-talk between basic helix-loop-helix/Per-Arnt-Sim homology transcription factors. Journal of Biological Chemistry, 277(12), 10236-10243. DOI Scopus63 WoS62 Europe PMC51

• Conference Papers

  Year	Citation
  2017	Bond, C., Liu, C., Kawamata, F., Mckeone, D., Jamieson, S., Pearson, S., . . . Whitehall, V. (2017). Oncogenic <i>BRAF</i> mutation induces widespread DNA hypermethylation in a murine model for human serrated colorectal neoplasia. In JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Vol. 32 (pp. 15). WILEY.

• Conference Items

  Year	Citation
  2024	Mossner, M., Househam, J., Kyle, P., Donato-Brown, D., Woods, S. L., Heide, T., . . . Graham, T. A. (2024). Evolutionary dynamics of phenotypic plasticity in metastatic colorectal cancer. Poster session presented at the meeting of Abstracts of the 6th Joint Meeting with the Royal Society of Medicine, 215th Scientific Meeting of the Pathological Society of Great Britain & Ireland, as published in Journal of Pathology. London, UK: Wiley. DOI
  2019	Enomoto, A., Mizutani, Y., Kobayashi, H., Iida, T., Woods, S. L., Worthley, D. L., & Takahashi, M. (2019). Identification of cancer-associated fibroblasts that suppress pancreatic cancer progression. Poster session presented at the meeting of CANCER RESEARCH. Atlanta, GA: AMER ASSOC CANCER RESEARCH. DOI
  2017	Woods, S. L., Lannagan, T. R. M., Suzuki, N., Yang, M., Lee, Y. K., Wang, T., . . . Worthley, D. L. (2017). Bridging the GAPP between the laboratory and clinic to prevent gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS). Poster session presented at the meeting of JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. WILEY.
  2017	Suzuki, N., Hata, M., Hikiba, Y., Ihara, S., Kosuke, S., Nakagawa, H., . . . Koike, K. (2017). Metastatic gastric signet ring cell carcinoma organoids generated from normal mouse stomach. Poster session presented at the meeting of JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. WILEY.
  2017	Lannagan, T. R. M., Woods, S. L., Wang, T., Somashekar, R., Yang, M., Ng, J. Q., . . . Worthley, D. L. (2017). Gremlin 1-expressing intestinal reticular stem cells give rise to cancer-associated fibroblasts in a mouse model of colorectal cancer. Poster session presented at the meeting of JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. WILEY.
  2017	Lannagan, T. R. M., Lee, Y. K., Gieniec, K., Wang, T., Somashekar, R., Yang, M., . . . Woods, S. L. (2017). The development of a state-of the art, high-sensitivity stool DNA test to improve screening for serrated polyps and early lesions. Poster session presented at the meeting of JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. WILEY.

• Preprint

  Year	Citation
  2023	Ying Li, C. M., Tomita, Y., Dhakal, B., Tin, T., Li, R., Wright, J. A., . . . Fenix, K. (2023). Generation and assessment of cytokine-induced killer cells for the treatment of colorectal cancer liver metastases. DOI
  2021	Cooper, R. M., Wright, J. A., Ng, J. Q., Goyne, J. M., Suzuki, N., Lee, Y. K., . . . Hasty., J. (2021). Engineered bacteria detect tumor DNA. DOI

BIOCHEMISTRY III: Cancer, Stem Cell & Dev Sem 2 2019-22 (3001, 3235, 3520)

• Current Higher Degree by Research Supervision (University of Adelaide)

  Date	Role	Research Topic	Program	Degree Type	Student Load	Student Name
  2024	Principal Supervisor	Harnessing tumour specific evolution of probiotic bacteria to engineer next-generation bowel cancer treatments	Doctor of Philosophy	Doctorate	Full Time	Miss Julia Leeflang
  2024	Principal Supervisor	Investigating colorectal cancer associated gut microbiome changes to engineer next generation cancer prevention strategies	Master of Philosophy (Medical Science)	Master	Full Time	Miss Sadia Tasnim Hasan
  2023	Principal Supervisor	Precision medicine for stomach cancer using patient derived organoids	Doctor of Philosophy	Doctorate	Full Time	Ms Francisco Hettige Tharindie Natashiya Silva
  2023	Principal Supervisor	Personalising treatments for advanced cancer patients receiving intraperitoneal chemotherapy using patient-derived organoids.	Doctor of Philosophy	Doctorate	Part Time	Miss Harleen Kaur
  2021	Principal Supervisor	Probiotics to detect and treat bowel cancer	Doctor of Philosophy	Doctorate	Full Time	Miss Georgette Alexandra Radford

• Past Higher Degree by Research Supervision (University of Adelaide)

  Date	Role	Research Topic	Program	Degree Type	Student Load	Student Name
  2021 - 2023	Co-Supervisor	An Investigation of Biological Processes Underlying Neratinib-induced Gut Injury	Master of Philosophy (Medical Science)	Master	Full Time	Mr Phu Minh Triet Nguyen
  2021 - 2024	Principal Supervisor	Development of a syngeneic, orthotopic microsatellite instability mouse model of colorectal cancer	Master of Philosophy (Medical Science)	Master	Part Time	Miss Elaine May Thomas
  2020 - 2021	Co-Supervisor	The Roles of Cancer-Associated Fibroblasts in Colorectal Carcinogenesis	Doctor of Philosophy under a Jointly-awarded Degree Agreement with	Doctorate	Full Time	Mr Hiroki Kobayashi
  2017 - 2021	Co-Supervisor	Investigating the Contribution of Specific Cancer-Associated Fibroblast Subsets to Colorectal Tumourigenesis	Doctor of Philosophy	Doctorate	Full Time	Miss Krystyna Anna Gieniec

• Committee Memberships

  Date	Role	Committee	Institution	Country
  2021 - ongoing	Convener	GESA Research Workshop Convenor	Gastroenterological Society of Australia	Australia
  2019 - ongoing	Member	GESA Research and Grants Committee	Gastroenterological Society of Australia	Australia
  2019 - 2020	Chair	E/MCR group, Faculty of Health Science	University of Adelaide	Australia
  2019 - 2020	Member	SAHMRI Community Advisory Group	SAHMRI	Australia
  2019 - ongoing	Member	Faculty of Health Science Research Committee	The University of Adelaide	Australia
  2019 - 2019	Member	AGITG Trainee Workshop Faculty Organising Committee	Australasian Gastro-Intestinal Trials Group	Australia
  2018 - 2020	Member	Victorian Cancer Council ECRF Review Panel Member	Victorian Cancer Council	Australia
  2018 - ongoing	Member	GESA Scientific Program Committee, Research Workshop	Gastroenterological Society of Australia	Australia
  2018 - ongoing	Member	AGITG Annual Scientific Meeting Translational Research Sub-Committee	Australasian Gastro-Intestinal Trials Group	Australia
  2017 - ongoing	Member	Cure Cancer Australia Research Consultative Committee	Cure Cancer Australia	Australia
  2016 - ongoing	Co-Chair	SAHMRI E/MCR Working Group	SAHMRI	Australia

• Memberships

  Date	Role	Membership	Country
  2018 - ongoing	Member	NHMRC Grant Review Panel	Australia

• Community Engagement

  Date	Title	Engagement Type	Institution	Country
  2016 - ongoing	Co-organiser Consumer Bowel Cancer Research Interest Group	Scientific Community Engagement	SAHMRI/University of Adelaide	-

• Position: Senior Research Fellow (D)
• Phone: 81284386
• Email: susan.woods@adelaide.edu.au
• Campus: North Terrace
• Building: SAHMRI - South, floor 5
• Org Unit: Medical Specialties