Srijan Shrestha

Srijan Shrestha

Health and Medical Sciences Faculty Office

Faculty of Health and Medical Sciences


Srijan Shrestha is studying at The University of Adelaide, Department of Pharmacology (Ph.D.). Srijan completed his Master's degree focusing on the various small molecules that have the potential to become future therapeutics for diabetes and Alzheimer's disease. His current project is 'Marine-derived phlorotannins and their potential applications". His work in these areas has been published in high-impact-factor and peer-reviewed journals, including ACS, RSC, Elsevier, MDPI, and Springer.

  • Journals

    Year Citation
    2022 Laws, J. S., Shrestha, S., & Smid, S. D. (2022). Cannabis terpenes display variable protective and anti-aggregatory actions against neurotoxic β amyloid in vitro: highlighting the protective bioactivity of α-bisabolol in motorneuronal-like NSC-34 cells. NeuroToxicology, 90, 81-87.
    DOI
    2022 Shrestha, S., Choi, J. S., Zhang, W., & Smid, S. D. (2022). Neuroprotective activity of macroalgal fucofuroeckols against amyloid β peptide-induced cell death and oxidative stress. International Journal of Food Science and Technology, 57(7), 4286-4295.
    DOI
    2021 Shrestha, S., Zhang, W., & Smid, S. D. (2021). Phlorotannins: A review on biosynthesis, chemistry and bioactivity. Food Bioscience, 39, 100832-1-100832-11.
    DOI Scopus28 WoS26
    2021 Shrestha, S., Johnston, M. R., Zhang, W., & Smid, S. D. (2021). A phlorotannin isolated from Ecklonia radiata, Dibenzodioxin-fucodiphloroethol, inhibits neurotoxicity and aggregation of β-amyloid. Phytomedicine Plus, 1(4), 100125-1-100125-9.
    DOI Scopus4
    2020 Shrestha, S., Zhang, W., Begbie, A. J., Pukala, T. L., & Smid, S. D. (2020). Ecklonia radiata extract containing eckol protects neuronal cells against Aβ1-42 evoked toxicity and reduces aggregate density.. Food Funct, 11(7), 6509-6516.
    DOI Scopus6 WoS5 Europe PMC1
    2020 Ha, M. T., Shrestha, S., Tran, T. H., Kim, J. A., Woo, M. H., Choi, J. S., & Min, B. S. (2020). Inhibition of PTP1B by farnesylated 2-arylbenzofurans isolated from Morus alba root bark: unraveling the mechanism of inhibition based on in vitro and in silico studies. Archives of Pharmacal Research, 43(9), 961-975.
    DOI Scopus9 WoS6 Europe PMC3
    2020 Paudel, P., Shrestha, S., Park, S. E., Seong, S. H., Fauzi, F. M., Jung, H. A., & Choi, J. S. (2020). Emodin Derivatives as Multi-Target-Directed Ligands Inhibiting Monoamine Oxidase and Antagonizing Vasopressin V<inf>1A</inf>Receptors. ACS Omega, 5(41), 26720-26731.
    DOI Scopus3 WoS3 Europe PMC2
    2019 Wagle, A., Seong, S. H., Shrestha, S., Ah Jung, H., & Choi, J. S. (2019). Korean thistle (cirsium japonicum var. Maackii (Maxim.) Matsum.): A potential dietary supplement against diabetes and Alzheimer’s disease. Molecules, 24(3), 19 pages.
    DOI Scopus14 Europe PMC5
    2019 Shrestha, S., Seong, S. H., Park, S. G., Min, B. S., Jung, H. A., & Choi, J. S. (2019). Insight into the PTP1B inhibitory activity of arylbenzofurans: An in vitro and in silico study. Molecules, 24(16), 11 pages.
    DOI Scopus9 WoS8
    2019 Paudel, P., Seong, S. H., Shrestha, S., Jung, H. A., & Choi, J. S. (2019). In Vitro and in Silico Human Monoamine Oxidase Inhibitory Potential of Anthraquinones, Naphthopyrones, and Naphthalenic Lactones from Cassia obtusifolia Linn Seeds. ACS Omega, 4(14), 16139-16152.
    DOI Scopus14 WoS12 Europe PMC7
    2019 Yang, S. J., Paudel, P., Shrestha, S., Seong, S. H., Jung, H. A., & Choi, J. S. (2019). In vitro protein tyrosine phosphatase 1B inhibition and antioxidant property of different onion peel cultivars: A comparative study. Food Science and Nutrition, 7(1), 205-215.
    DOI Scopus6 WoS6 Europe PMC4
    2018 Shrestha, S., Seong, S. H., Paudel, P., Jung, H. A., & Choi, J. S. (2018). Structure related inhibition of enzyme systems in cholinesterases and BACE1 in vitro by naturally occurring naphthopyrone and its glycosides isolated from cassia obtusifolia. Molecules, 23(1), 69.
    DOI Scopus22 Europe PMC12
    2018 Shrestha, S., Paudel, P., Seong, S. H., Min, B. S., Seo, E. K., Jung, H. A., & Choi, J. S. (2018). Two new naphthalenic lactone glycosides from Cassia obtusifolia L. seeds. Archives of Pharmacal Research, 41(7), 737-742.
    DOI Scopus9 Europe PMC6
    2018 Shrestha, S. (2018). PTP1B inhibitory activity and molecular docking analysis of stilbene derivatives from the rhizomes of Rheum undulatum L.. Fitoterapia, 131, 119-126.
    DOI Scopus19 Europe PMC3
    2018 Koirala, P., Seong, S. H., Zhou, Y., Shrestha, S., Jung, H. A., & Choi, J. S. (2018). Structure–Activity relationship of the tyrosinase inhibitors kuwanon G, mulberrofuran G, and albanol B from morus species: A kinetics and molecular docking Study. Molecules, 23(6), 1413.
    DOI Scopus17 Europe PMC4
  • Memberships

    Date Role Membership Country
    2021 - ongoing Member International Society for Neurochemistry Australia
    2021 - ongoing Member Australia New Zealand Marine Biotechnology Society Australia

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