Shu Yie Janine Tam

Shu Yie Janine Tam

Higher Degree by Research Candidate

Adelaide Medical School

Faculty of Health and Medical Sciences


Inflammation of the intestinal tract can be an acute or chronic manifestation of intestinal disease which can cause irritation, exposure to bacteria and a dysregulation of the homeostatic balance. This leads to a range of debilitating symptoms that heavily affects patient quality of life. Current treatment modalities that are being used for intestinal inflammation are associated with a range of disadvantages including poor efficacy and unwanted side effects. A lack of knowledge of intestinal pathophysiology and difficulty in assessing the site of disease impairs the ability to improve therapy delivery and target direct injury mechanisms.

I am investigating alternate targeted methods of delivering therapeutics to the inflamed gastrointestinal tract in order to improve on current conventional delivery methods which have issues with efficacy, infection risks and patient comfort. This study will define a new strategy for therapeutic delivery to attenuate inflammatory responses in human disease that will not only improve their treatment outcomes but also improve their quality of life. 

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  • Journals

    Year Citation
    2019 Tam, S., Coller, J., Wignall, A., Gibson, R., Khatri, A., Barbé, C., & Bowen, J. (2019). Intestinal accumulation of silica particles in a rat model of dextran sulfate sodium-induced colitis. Annals of Gastroenterology, 32(6), 584-592.
    DOI

 

2018: Gastroenterological Society of Australia (GESA) Travel Grant

2018: Adelaide Graduate Research Scholarship (AGRS)

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  • Memberships

    Date Role Membership Country
    2018 - ongoing Member Australian Society for Medical Research (ASMR) Australia

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