Sher Li Tan

Dr Sher Li Tan

PhD Candidate

School of Biological Sciences

Faculty of Sciences, Engineering and Technology

Alzheimer’s disease (AD) is the most common form of dementia, which affects memory, behaviour and daily functioning of affected patients. It is an irreversible and progressive neurodegenerative disease and its pathological characteristics consist of amyloid-beta (Aβ) plaques and phosphorylated tau that accumulate in the brain. The unknown factors surrounding the mechanism of neurodegeneration regarding AD pathology pose a significant challenge in the development of effective novel therapeutic approaches. 

My research focuses on Drosophila melanogaster modelling of AD as a genetic screening tool in order to determine the functional contribution of cellular components associated with AD pathogenesis.

  • Journals

    Year Citation
    2023 Tan, S. L., Hewson, L. J., Mustaffar, N. F., He, Q. Q., Wimmer, N., Trim, P. J., . . . Lau, A. A. (2023). Substrate reduction therapy in a<i>Drosophila melanogaster</i>model of Sanfilippo syndrome.
  • Position: PhD Candidate
  • Email:
  • Campus: North Terrace
  • Building: Molecular Life Sciences, floor 1
  • Org Unit: Research Scholars (Positions)

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