Dr Sher Li Tan
PhD Candidate
School of Biological Sciences
Faculty of Sciences, Engineering and Technology
Alzheimer’s disease (AD) is the most common form of dementia, which affects memory, behaviour and daily functioning of affected patients. It is an irreversible and progressive neurodegenerative disease and its pathological characteristics consist of amyloid-beta (Aβ) plaques and phosphorylated tau that accumulate in the brain. The unknown factors surrounding the mechanism of neurodegeneration regarding AD pathology pose a significant challenge in the development of effective novel therapeutic approaches.
My research focuses on Drosophila melanogaster modelling of AD as a genetic screening tool in order to determine the functional contribution of cellular components associated with AD pathogenesis.
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Appointments
Date Position Institution name 2018 - 2021 Higher Degree by Research Candidate University of Adelaide -
Awards and Achievements
Date Type Title Institution Name Country Amount 2021 Award Finalist in the Faculty of Sciences 3MT Competition 2021 University of Adelaide Australia - 2018 Scholarship Adelaide Graduate Research Scholarship University of Adelaide Australia - -
Language Competencies
Language Competency English Can read, write, speak, understand spoken and peer review Malay Can read, write, speak and understand spoken -
Education
Date Institution name Country Title 2017 - 2017 University of Adelaide Australia Bachelor of Health and Medical Sciences (Honours) 2014 - 2016 University of Adelaide Australia Bachelor of Science -
Research Interests
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Journals
Year Citation 2023 Tan, S. L., Hewson, L. J., Mustaffar, N. F., He, Q. Q., Wimmer, N., Trim, P. J., . . . Lau, A. A. (2023). Substrate reduction therapy in a<i>Drosophila melanogaster</i>model of Sanfilippo syndrome.
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Committee Memberships
Date Role Committee Institution Country 2021 - ongoing Member State Representative (SA) for Australian Fly Meeting 2021 AusFly Australia 2019 - 2019 Member SCHOOL OF BIOLOGICAL SCIENCES POSTGRADUATE SYMPOSIUM 2019 University of Adelaide Australia 2019 - 2019 Member Dementia, Ageing and Neurodegenerative DISeases group (DANDIS) Australasian Neuroscience Society Australia -
Memberships
Date Role Membership Country 2022 - ongoing Member Genetics Society of America Australia 2019 - ongoing Member Australasian Neuroscience Society Australia
Connect With Me
External Profiles
