Sharon Paton

Ms Sharon Paton

Technical Officer

School of Pharmacy and Biomedical Science

College of Health

I am currently involved in a variety of research projects within both the Mesenchymal Stem Cell Research Group and the Myeloma Research Group, and have been extensively involved in research and development support in developing biological products for a broad field of regenerative medicine, including large scale production of low passage MSCs for various clinical trials. I am also involved in Laboratory Management and provide technical support for Honours, PhD and Senior Post Doctoral staff members.

Year Citation
2025 Smith, N., Cakouros, D., Ryan, F. J., Lynn, D. J., Paton, S., Arthur, A., & Gronthos, S. (2025). DNA hydroxymethylases Tet1 and Tet2 regulate bone aging and BMSC metabolism through the IGF-1/ mTOR signalling axis. Stem Cells, 43(8), sxaf026-1-sxaf026-17.
DOI WoS1
2024 Camp, E., Garcia, L. G., Pribadi, C., Paton, S., Vasilev, K., Anderson, P., & Gronthos, S. (2024). Targeting of C-ROS-1 Activity Using a Controlled Release Carrier to Treat Craniosynostosis in a Preclinical Model of Saethre-Chotzen Syndrome. Journal of Tissue Engineering and Regenerative Medicine, 2024(8863925), 8863925-1-8863925-12.
DOI
2024 Campbell, J. M., Habibalahi, A., Agha, A., Handley, S., Knab, A., Xu, X., . . . Goldys, E. M. (2024). Single cell, Label free Characterisation of Human Mesenchymal Stromal cell Stemness and Future Growth Potential by Autofluorescence Multispectral Imaging. Stem Cell Rev Rep, 20(8), 2283-2292.
DOI
2024 Campbell, J. M., Mahbub, S. B., Anwer, A. G., Habibalahi, A., Gronthos, S., Paton, S., . . . Goldys, E. M. (2024). Multispectral Imaging of Collagen, NAD(P)H and Flavin Autofluorescence in Mesenchymal Stem Cells Undergoing Trilineage Differentiation. Cells, 13(20), 1731-1-1731-14.
DOI Europe PMC1
2022 Kutyna, M. M., Kok, C. H., Lim, Y., Campbell, D., Paton, S., Thompson-Peach, C. A. L., . . . Hiwase, D. (2022). Senolytic Therapy Can Reverse Senescent Bone Marrow Stroma of Therapy-Related Myeloid Neoplasm. Blood, 140(Supplement 1), 9755-9756.
DOI
2022 Kutyna, M. M., Kok, C. H., Lim, Y., Tran, E. N. H., Campbell, D., Paton, S., . . . Hiwase, D. K. (2022). A senescence stress secretome is a hallmark of therapy-related myeloid neoplasm stromal tissue occurring soon after cytotoxic exposure. Leukemia, 36(11), 2678-2689.
DOI Scopus17 WoS17 Europe PMC17
2021 Campbell, J. M., Mahbub, S., Habibalahi, A., Paton, S., Gronthos, S., & Goldys, E. (2021). Ageing human bone marrow mesenchymal stem cells have depleted NAD(P)H and distinct multispectral autofluorescence. GeroScience, 43(2), 859-868.
DOI Scopus14 WoS16 Europe PMC14
2020 Arthur, A., Paton, S., Zannettino, A. C. W., & Gronthos, S. (2020). Conditional knockout of ephrinB1 in osteogenic progenitors delays the process of endochondral ossification during fracture repair. Bone, 132, 115189-1-115189-10.
DOI Scopus9 WoS7 Europe PMC7
2020 Kutyna, M. M., Wee, L. Y. A., Paton, S., Cakouros, D., Arthur, A., Chhetri, R., . . . Hiwase, D. K. (2020). Therapy-Related Myeloid Neoplasm Has a Distinct Pro-Inflammatory Bone Marrow Microenvironment and Delayed DNA Damage Repair. Blood, 136(Supplement 1), 37-38.
DOI
2019 Arthur, A., Nguyen, T. M., Paton, S., Zannettino, A. C. W., & Gronthos, S. (2019). Loss of EfnB1 in the osteogenic lineage compromises their capacity to support hematopoietic stem/progenitor cell maintenance. Experimental Hematology, 69, 43-53.
DOI Scopus14 WoS14 Europe PMC13
2019 Campbell, J. M., Habibalahi, A., Mahbub, S., Gosnell, M., Anwer, A. G., Paton, S., . . . Goldys, E. (2019). Non-destructive, label free identification of cell cycle phase in cancer cells by multispectral microscopy of autofluorescence. BMC Cancer, 19(1), 1-11.
DOI Scopus28 WoS27 Europe PMC29
2018 Arthur, A., Nguyen, T., Paton, S., Klisuric, A., Zannettino, A., & Gronthos, S. (2018). The osteoprogenitor-specific loss of ephrinB1 results in an osteoporotic phenotype affecting the balance between bone formation and resorption. Scientific Reports, 8(1), 12756-1-12756-12.
DOI Scopus16 WoS15 Europe PMC12
2017 Wu, J., Shimmon, S., Paton, S., Daly, C., Goldschlager, T., Gronthos, S., . . . Ghosh, P. (2017). Pentosan polysulfate binds to STRO-1+mesenchymal progenitor cells, is internalized, and modifies gene expression: A novel approach of pre-programing stem cells for therapeutic application requiring their chondrogenesis. Stem Cell Research and Therapy, 8(1), 15 pages.
DOI Scopus9 WoS9 Europe PMC8
2016 Nguyen, T., Arthur, A., Purton, L., Hayball, J., Zannettino, A., Paton, S., . . . Gronthos, S. (2016). EphB4 enhances bone marrow stromal stem cell-mediated support of haematopoiesis. British journal of haematology, 173(30, S1,S1), 30.
2016 Nguyen, T., Arthur, A., Paton, S., Hemming, S., Panagopoulos, R., Codrington, J., . . . Gronthos, S. (2016). Loss of ephrinB1 in osteogenic progenitor cells impedes endochondral ossification and compromises bone strength integrity during skeletal development. Bone, 93, 12-21.
DOI Scopus20 WoS20 Europe PMC15
2015 Nguyen, T., Arthur, A., Panagopoulos, R., Paton, S., Hayball, J., Zannettino, A., . . . Gronthos, S. (2015). EphB4 expressing stromal cells exhibit an enhanced capacity for hematopoietic stem cell maintenance. Stem Cells, 33(9), 2838-2849.
DOI Scopus30 WoS31 Europe PMC26
2014 Richardson, J., Psaltis, P., Frost, L., Paton, S., Carbone, A., Bertaso, A., . . . Worthley, S. (2014). Incremental benefits of repeated mesenchymal stromal cell administration compared with solitary intervention after myocardial infarction. Cytotherapy, 16(4), 460-470.
DOI Scopus22 WoS22 Europe PMC19
2013 Richardson, J., Bertaso, A., Frost, L., Psaltis, P., Carbone, A., Koschade, B., . . . Worthley, S. (2013). Cardiac magnetic resonance, transthoracic and transoesophageal echocardiography: a comparison of invivo assessment of ventricular function in rats. Laboratory Animals, 47(4), 291-300.
DOI Scopus7 WoS6 Europe PMC5
2013 Richardson, J., Bertaso, A., Psaltis, P., Frost, L., Carbone, A., Paton, S., . . . Worthley, S. (2013). Impact of timing and dose of mesenchymal stromal cell therapy in a preclinical model of acute myocardial infarction. Journal of Cardiac Failure, 19(5), 342-353.
DOI Scopus47 WoS43 Europe PMC36
2012 Richardson, J., Frost, L., Bertaso, A., Carbone, A., Paton, S., Nelson, A., . . . Worthley, S. (2012). Sequential Mesenchymal Stem Cell Interventions Produce Greater Myocardial Repair than Solitary Treatment in Rats After Acute Myocardial Infarction. Heart, Lung and Circulation, 21, S92-S93.
DOI
2012 Richardson, J., Paton, S., Frost, L., Carbone, A., Bertaso, A., Nelson, A., . . . Worthley, S. (2012). Prospectively Isolated, Hypoxic-Preconditioned Mesenchymal Stem Cells Significantly Attenuate Myocardial Infarction-Induced Ventricular Dysfunction In Rats. Heart, Lung and Circulation, 21, S90.
DOI
2012 Richardson, J., Frost, L., Bertaso, A., Carbone, A., Paton, S., Nelson, A., . . . Worthley, S. (2012). Immediate Mesenchymal Stem Cell Therapy Provides Greater Attenuation of Myocardial Injury Than Deferred Treatment in Rats After Acute Myocardial Infarction. Heart, Lung and Circulation, 21, S2.
DOI
2010 Zannettino, A., Paton, S., Itescu, S., & Gronthos, S. (2010). Comparative assessment of the osteoconductive properties of different biomaterials in vivo seeded with human or ovine mesenchymal stem/stromal cells. Tissue Engineering. Part A. Tissue Engineering, 16(12), 3579-3587.
DOI Scopus32 WoS29 Europe PMC26
2010 Psaltis, P., Paton, S., See, F., Arthur, A., Martin, S., Itescu, S., . . . Zannettino, A. (2010). Enrichment for STRO-1 expression enhances the cardiovascular paracrine activity of human bone marrow-derived mesenchymal cell populations. Journal of Cellular Physiology, 223(2), 530-540.
DOI Scopus134 WoS123 Europe PMC111
2009 Gronthos, S., McCarty, R., Mrozik, K., Fitter, S., Paton, S., Menicanin, D., . . . Zannettino, A. (2009). Heat shock protein-90 beta is expressed at the surface of multipotential mesenchymal precursor cells: Generation of a novel monoclonal antibody, STRO-4, with specificity for mesenchymal precursor cells from human and ovine tissues. Stem Cells and Development, 18(9), 1253-1261.
DOI Scopus74 WoS62 Europe PMC52
2009 Psaltis, P. J., See, F., Paton, S., Martens, T. P., Itescu, S., Worthley, S. G., . . . Zannettino, A. C. W. (2009). STRO-1 immunoselection enhances the biological properties and cardiovascular paracrine effects of bone marrow mesenchymal stromal cells. EUROPEAN HEART JOURNAL, 30, 501.
2008 Zannettino, A., Paton, S., Kortesidis, A., Khor, F., Itescu, S., & Gronthos, S. (2008). Human mulipotential mesenchymal/stromal stem cells are derived from a discrete subpopulation of STRO-1bright/CD34-/CD45-/glycophorin-A-bone marrow cells. Haematologica, 92(12), 1707-1708.
DOI Scopus78 WoS66 Europe PMC53
2008 Zannettino, A., Paton, S., Arthur, A., Khor, F., Itescu, S., Gimble, J., & Gronthos, S. (2008). Multipotential human adipose-derived stromal stem cells exhibit a perivascular phenotype in vitro and in vivo. Journal of Cellular Physiology, 214(2), 413-421.
DOI Scopus496 WoS432 Europe PMC377
1997 Kaur, P., Paton, S., Furze, J., Wrin, J., Olsen, S., Danks, J., & Scurry, J. (1997). Identification of a cell surface protein with a role in stimulating human keratinocyte proliferation, expressed during development and carcinogenesis. Journal of Investigative Dermatology, 109(2), 194-199.
DOI Scopus7 WoS7 Europe PMC7
1996 Kaur, P., Paton, S., Furze, J., & Wrin, J. (1996). Identification of a cell surface molecule associated with proliferation during development and carcinogenesis in human keratinocytes.. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 107(3), 155.

Year Citation
2021 Kutyna, M., Kok, C. H., Wee, L. Y., Paton, S., Chhetri, R., Thomas, D., . . . Hiwase, D. (2021). BONE MARROW MICROENVIRONMENT IN THERAPY-RELATED MYELOID NEOPLASMS IS DISTINCT FROM OTHER MYELOID NEOPLASMS, PROBABLY DRIVEN BY PRIOR CYTOTOXIC THERAPY. In LEUKEMIA RESEARCH Vol. 108 (pp. S18-S19). PERGAMON-ELSEVIER SCIENCE LTD.
2021 Kutyna, M. M., Kok, C. H., Paton, S., Cakouros, D., Arthur, A., Hughes, T. P., . . . Hiwase, D. (2021). Distinct Senescent Bone Marrow Microenvironment in Therapy-Related Myeloid Neoplasms. In BLOOD Vol. 138 (pp. 4 pages). GA, Atlanta: AMER SOC HEMATOLOGY.
DOI WoS1
2020 Campbell, J. M., Habibalahi, A., Mahbub, S., Paton, S., Gronthos, S., & Goldys, E. (2020). Multispectral characterisation of mesenchymal stem/stromal cells: Age, cell cycle, senescence, and pluripotency. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE Vol. 11251 (pp. 1-7). online: SPIE.
DOI Scopus3 WoS2
2019 Arthur, A., Paton, S., Gronthos, S., & Zannettino, A. (2019). The Loss of ephrinB1 in Osteoprogenitors Delays Fracture Repair. In JOURNAL OF BONE AND MINERAL RESEARCH Vol. 34 (pp. 326). Orlando, FL: WILEY.
2019 Kutyna, M., Paton, S., Gronthos, S., & Hiwase, D. (2019). ABERRANT BONE MARROW MICROENVIRONMENT IN THERAPY RELATED MYELOID NEOPLASM. In EXPERIMENTAL HEMATOLOGY Vol. 76 (pp. E3-E4). ELSEVIER SCIENCE INC.
2016 Nguyen, T. M., Arthur, A., Paton, S., Purton, L. E., & Gronthos, S. (2016). EphrinB1 expressing stromal cells exhibit an enhanced capacity for haematopoietic stem cell maintenance. In BRITISH JOURNAL OF HAEMATOLOGY Vol. 173 (pp. 30). British Soc Haematol, Glasgow, SCOTLAND: WILEY-BLACKWELL.

Year Citation
2019 Kutyna, M. M., Wee, A., Paton, S., Cakouros, D., Arthur, A., Chhetri, R., . . . Hiwase, D. K. (2019). Aberrant Bone Marrow Microenvironment in Therapy Related Myeloid Neoplasm (t-MN). Poster session presented at the meeting of BLOOD. FL, Orlando: ELSEVIER.
DOI WoS2
2012 Richardson, J., Bertaso, A., Wong, D., Frost, L., Carbone, A., Nelson, A., . . . Worthley, S. (2012). Assessment of regional myocardial function in rats using 1.5T cardiac magnetic resonance imaging. Poster session presented at the meeting of Abstracts of the 60th Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand (CSANZ), as published in Heart, Lung and Circulation. Brisbane, QLD: Elsevier.
DOI

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