Mrs Sharon Paton

Technical Officer

School of Biomedicine

Faculty of Health and Medical Sciences

My Research
Publications
Contact

I am currently involved in a variety of research projects within both the Mesenchymal Stem Cell Research Group and the Myeloma Research Group, and have been extensively involved in research and development support in developing biological products for a broad field of regenerative medicine, including large scale production of low passage MSCs for various clinical trials. I am also involved in Laboratory Management and provide technical support for Honours, PhD and Senior Post Doctoral staff members.

Journals

Year	Citation
2024	Camp, E., Garcia, L. G., Pribadi, C., Paton, S., Vasilev, K., Anderson, P., & Gronthos, S. (2024). Targeting of C-ROS-1 Activity Using a Controlled Release Carrier to Treat Craniosynostosis in a Preclinical Model of Saethre-Chotzen Syndrome. Journal of Tissue Engineering and Regenerative Medicine, 2024, 8863925-1-8863925-12. DOI
2024	Campbell, J. M., Habibalahi, A., Agha, A., Handley, S., Knab, A., Xu, X., . . . Goldys, E. M. (2024). Single cell, Label free Characterisation of Human Mesenchymal Stromal cell Stemness and Future Growth Potential by Autofluorescence Multispectral Imaging. Stem Cell Reviews and Reports, 10 pages. DOI
2024	Campbell, J. M., Mahbub, S. B., Anwer, A. G., Habibalahi, A., Gronthos, S., Paton, S., . . . Goldys, E. M. (2024). Multispectral Imaging of Collagen, NAD(P)H and Flavin Autofluorescence in Mesenchymal Stem Cells Undergoing Trilineage Differentiation.. Cells, 13(20), 1731. DOI
2022	Kutyna, M. M., Kok, C. H., Lim, Y., Campbell, D., Paton, S., Thompson-Peach, C. A. L., . . . Hiwase, D. (2022). Senolytic Therapy Can Reverse Senescent Bone Marrow Stroma of Therapy-Related Myeloid Neoplasm. Blood, 140(Supplement 1), 9755-9756. DOI
2022	Kutyna, M. M., Kok, C. H., Lim, Y., Tran, E. N. H., Campbell, D., Paton, S., . . . Hiwase, D. K. (2022). A senescence stress secretome is a hallmark of therapy-related myeloid neoplasm stromal tissue occurring soon after cytotoxic exposure. Leukemia, 36(11), 2678-2689. DOI Scopus12 WoS4 Europe PMC10
2021	Campbell, J. M., Mahbub, S., Habibalahi, A., Paton, S., Gronthos, S., & Goldys, E. (2021). Ageing human bone marrow mesenchymal stem cells have depleted NAD(P)H and distinct multispectral autofluorescence. GeroScience, 43(2), 859-868. DOI Scopus11 WoS10 Europe PMC9
2020	Arthur, A., Paton, S., Zannettino, A. C. W., & Gronthos, S. (2020). Conditional knockout of ephrinB1 in osteogenic progenitors delays the process of endochondral ossification during fracture repair. Bone, 132, 115189-1-115189-10. DOI Scopus9 WoS7 Europe PMC5
2020	Kutyna, M. M., Wee, L. Y. A., Paton, S., Cakouros, D., Arthur, A., Chhetri, R., . . . Hiwase, D. K. (2020). Therapy-Related Myeloid Neoplasm Has a Distinct Pro-Inflammatory Bone Marrow Microenvironment and Delayed DNA Damage Repair. Blood, 136(Supplement 1), 37-38. DOI
2019	Arthur, A., Nguyen, T. M., Paton, S., Zannettino, A. C. W., & Gronthos, S. (2019). Loss of EfnB1 in the osteogenic lineage compromises their capacity to support hematopoietic stem/progenitor cell maintenance. Experimental Hematology, 69, 43-53. DOI Scopus14 WoS13 Europe PMC10
2019	Campbell, J. M., Habibalahi, A., Mahbub, S., Gosnell, M., Anwer, A. G., Paton, S., . . . Goldys, E. (2019). Non-destructive, label free identification of cell cycle phase in cancer cells by multispectral microscopy of autofluorescence. BMC Cancer, 19(1), 1-11. DOI Scopus20 WoS16 Europe PMC13
2018	Arthur, A., Nguyen, T., Paton, S., Klisuric, A., Zannettino, A., & Gronthos, S. (2018). The osteoprogenitor-specific loss of ephrinB1 results in an osteoporotic phenotype affecting the balance between bone formation and resorption. Scientific Reports, 8(1), 12756-1-12756-12. DOI Scopus14 WoS11 Europe PMC6
2017	Wu, J., Shimmon, S., Paton, S., Daly, C., Goldschlager, T., Gronthos, S., . . . Ghosh, P. (2017). Pentosan polysulfate binds to STRO-1+mesenchymal progenitor cells, is internalized, and modifies gene expression: A novel approach of pre-programing stem cells for therapeutic application requiring their chondrogenesis. Stem Cell Research and Therapy, 8(1), 15 pages. DOI Scopus8 WoS8 Europe PMC6
2016	Nguyen, T., Arthur, A., Paton, S., Hemming, S., Panagopoulos, R., Codrington, J., . . . Gronthos, S. (2016). Loss of ephrinB1 in osteogenic progenitor cells impedes endochondral ossification and compromises bone strength integrity during skeletal development. Bone, 93, 12-21. DOI Scopus18 WoS17 Europe PMC12
2015	Nguyen, T., Arthur, A., Panagopoulos, R., Paton, S., Hayball, J., Zannettino, A., . . . Gronthos, S. (2015). EphB4 expressing stromal cells exhibit an enhanced capacity for hematopoietic stem cell maintenance. Stem Cells, 33(9), 2838-2849. DOI Scopus28 WoS26 Europe PMC21
2014	Richardson, J., Psaltis, P., Frost, L., Paton, S., Carbone, A., Bertaso, A., . . . Worthley, S. (2014). Incremental benefits of repeated mesenchymal stromal cell administration compared with solitary intervention after myocardial infarction. Cytotherapy, 16(4), 460-470. DOI Scopus21 WoS21 Europe PMC16
2013	Richardson, J., Bertaso, A., Frost, L., Psaltis, P., Carbone, A., Koschade, B., . . . Worthley, S. (2013). Cardiac magnetic resonance, transthoracic and transoesophageal echocardiography: a comparison of invivo assessment of ventricular function in rats. Laboratory Animals, 47(4), 291-300. DOI Scopus7 WoS6 Europe PMC4
2013	Richardson, J., Bertaso, A., Psaltis, P., Frost, L., Carbone, A., Paton, S., . . . Worthley, S. (2013). Impact of timing and dose of mesenchymal stromal cell therapy in a preclinical model of acute myocardial infarction. Journal of Cardiac Failure, 19(5), 342-353. DOI Scopus45 WoS41 Europe PMC30
2012	Richardson, J., Frost, L., Bertaso, A., Carbone, A., Paton, S., Nelson, A., . . . Worthley, S. (2012). Sequential Mesenchymal Stem Cell Interventions Produce Greater Myocardial Repair than Solitary Treatment in Rats After Acute Myocardial Infarction. Heart, Lung and Circulation, 21, S92-S93. DOI
2012	Richardson, J., Paton, S., Frost, L., Carbone, A., Bertaso, A., Nelson, A., . . . Worthley, S. (2012). Prospectively Isolated, Hypoxic-Preconditioned Mesenchymal Stem Cells Significantly Attenuate Myocardial Infarction-Induced Ventricular Dysfunction In Rats. Heart, Lung and Circulation, 21, S90. DOI
2012	Richardson, J., Frost, L., Bertaso, A., Carbone, A., Paton, S., Nelson, A., . . . Worthley, S. (2012). Immediate Mesenchymal Stem Cell Therapy Provides Greater Attenuation of Myocardial Injury Than Deferred Treatment in Rats After Acute Myocardial Infarction. Heart, Lung and Circulation, 21, S2. DOI
2010	Zannettino, A., Paton, S., Itescu, S., & Gronthos, S. (2010). Comparative assessment of the osteoconductive properties of different biomaterials in vivo seeded with human or ovine mesenchymal stem/stromal cells. Tissue Engineering. Part A. Tissue Engineering, 16(12), 3579-3587. DOI Scopus32 WoS29 Europe PMC23
2010	Psaltis, P., Paton, S., See, F., Arthur, A., Martin, S., Itescu, S., . . . Zannettino, A. (2010). Enrichment for STRO-1 expression enhances the cardiovascular paracrine activity of human bone marrow-derived mesenchymal cell populations. Journal of Cellular Physiology, 223(2), 530-540. DOI Scopus128 WoS115 Europe PMC92
2009	Gronthos, S., McCarty, R., Mrozik, K., Fitter, S., Paton, S., Menicanin, D., . . . Zannettino, A. (2009). Heat shock protein-90 beta is expressed at the surface of multipotential mesenchymal precursor cells: Generation of a novel monoclonal antibody, STRO-4, with specificity for mesenchymal precursor cells from human and ovine tissues. Stem Cells and Development, 18(9), 1253-1261. DOI Scopus71 WoS61 Europe PMC45
2009	Psaltis, P. J., See, F., Paton, S., Martens, T. P., Itescu, S., Worthley, S. G., . . . Zannettino, A. C. W. (2009). STRO-1 immunoselection enhances the biological properties and cardiovascular paracrine effects of bone marrow mesenchymal stromal cells. EUROPEAN HEART JOURNAL, 30, 501.
2008	Zannettino, A., Paton, S., Kortesidis, A., Khor, F., Itescu, S., & Gronthos, S. (2008). Human mulipotential mesenchymal/stromal stem cells are derived from a discrete subpopulation of STRO-1bright/CD34-/CD45-/glycophorin-A-bone marrow cells. Haematologica, 92(12), 1707-1708. DOI Scopus75 WoS66 Europe PMC49
2008	Zannettino, A., Paton, S., Arthur, A., Khor, F., Itescu, S., Gimble, J., & Gronthos, S. (2008). Multipotential human adipose-derived stromal stem cells exhibit a perivascular phenotype in vitro and in vivo. Journal of Cellular Physiology, 214(2), 413-421. DOI Scopus481 WoS417 Europe PMC341
1997	Kaur, P., Paton, S., Furze, J., Wrin, J., Olsen, S., Danks, J., & Scurry, J. (1997). Identification of a cell surface protein with a role in stimulating human keratinocyte proliferation, expressed during development and carcinogenesis. Journal of Investigative Dermatology, 109(2), 194-199. DOI Scopus7 WoS7 Europe PMC7
1996	Kaur, P., Paton, S., Furze, J., & Wrin, J. (1996). Identification of a cell surface molecule associated with proliferation during development and carcinogenesis in human keratinocytes.. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 107(3), 155.

Conference Papers

Year	Citation
2021	Kutyna, M., Kok, C. H., Wee, L. Y., Paton, S., Chhetri, R., Thomas, D., . . . Hiwase, D. (2021). BONE MARROW MICROENVIRONMENT IN THERAPY-RELATED MYELOID NEOPLASMS IS DISTINCT FROM OTHER MYELOID NEOPLASMS, PROBABLY DRIVEN BY PRIOR CYTOTOXIC THERAPY. In LEUKEMIA RESEARCH Vol. 108 (pp. S18-S19). PERGAMON-ELSEVIER SCIENCE LTD.
2021	Kutyna, M. M., Kok, C. H., Paton, S., Cakouros, D., Arthur, A., Hughes, T. P., . . . Hiwase, D. (2021). Distinct Senescent Bone Marrow Microenvironment in Therapy-Related Myeloid Neoplasms. In BLOOD Vol. 138 (pp. 4 pages). Atlanta, GA: AMER SOC HEMATOLOGY. DOI WoS1
2020	Campbell, J. M., Habibalahi, A., Mahbub, S., Paton, S., Gronthos, S., & Goldys, E. (2020). Multispectral characterisation of mesenchymal stem/stromal cells: Age, cell cycle, senescence, and pluripotency. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE Vol. 11251 (pp. 1-7). online: SPIE. DOI Scopus3 WoS1
2019	Arthur, A., Paton, S., Gronthos, S., & Zannettino, A. (2019). The Loss of ephrinB1 in Osteoprogenitors Delays Fracture Repair. In JOURNAL OF BONE AND MINERAL RESEARCH Vol. 34 (pp. 326). Orlando, FL: WILEY.
2019	Kutyna, M., Paton, S., Gronthos, S., & Hiwase, D. (2019). ABERRANT BONE MARROW MICROENVIRONMENT IN THERAPY RELATED MYELOID NEOPLASM. In EXPERIMENTAL HEMATOLOGY Vol. 76 (pp. E3-E4). ELSEVIER SCIENCE INC.
2016	Nguyen, T., Arthur, A., Purton, L., Hayball, J., Zannettino, A., Paton, S., . . . Gronthos, S. (2016). EphB4 enhances bone marrow stromal stem cell-mediated support of haematopoiesis. In BRITISH JOURNAL OF HAEMATOLOGY Vol. 173 (pp. 30). British Soc Haematol, Glasgow, SCOTLAND: WILEY-BLACKWELL.
2016	Nguyen, T. M., Arthur, A., Paton, S., Purton, L. E., & Gronthos, S. (2016). EphrinB1 expressing stromal cells exhibit an enhanced capacity for haematopoietic stem cell maintenance. In BRITISH JOURNAL OF HAEMATOLOGY Vol. 173 (pp. 30). British Soc Haematol, Glasgow, SCOTLAND: WILEY-BLACKWELL.

Conference Items

Year	Citation
2019	Kutyna, M. M., Wee, A., Paton, S., Cakouros, D., Arthur, A., Chhetri, R., . . . Hiwase, D. K. (2019). Aberrant Bone Marrow Microenvironment in Therapy Related Myeloid Neoplasm (t-MN). Poster session presented at the meeting of BLOOD. Orlando, FL: AMER SOC HEMATOLOGY. DOI WoS2
2012	Richardson, J., Bertaso, A., Wong, D., Frost, L., Carbone, A., Nelson, A., . . . Worthley, S. (2012). Assessment of regional myocardial function in rats using 1.5T cardiac magnetic resonance imaging. Poster session presented at the meeting of Abstracts of the 60th Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand (CSANZ), as published in Heart, Lung and Circulation. Brisbane, QLD: Elsevier. DOI

Year

Citation

2019

Kutyna, M. M., Wee, A., Paton, S., Cakouros, D., Arthur, A., Chhetri, R., . . . Hiwase, D. K. (2019). Aberrant Bone Marrow Microenvironment in Therapy Related Myeloid Neoplasm (t-MN). Poster session presented at the meeting of BLOOD. Orlando, FL: AMER SOC HEMATOLOGY.
DOI WoS2

2012

Richardson, J., Bertaso, A., Wong, D., Frost, L., Carbone, A., Nelson, A., . . . Worthley, S. (2012). Assessment of regional myocardial function in rats using 1.5T cardiac magnetic resonance imaging. Poster session presented at the meeting of Abstracts of the 60th Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand (CSANZ), as published in Heart, Lung and Circulation. Brisbane, QLD: Elsevier.
DOI

Position: Technical Officer
Phone: 81284695
Email: sharon.paton@adelaide.edu.au
Campus: North Terrace
Building: SAHMRI, floor 5 South
Org Unit: Medical Sciences

Mrs Sharon Paton

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