Prof Sharad Kumar

Bradley Distinguished Professor

Centre for Cancer Biology

College of Health

Eligible to supervise Masters and PhD - email supervisor to discuss availability.


I joined the University of South Australia (UniSA) in 2014 as Chair of Cancer Biology and Research Professor of Cell Biology.
After earning my PhD from the University of Adelaide and completing postdoctoral training at the University of Queensland, I held Research Scientist positions at CSIRO (Geelong), RIKEN (Tsukuba, Japan) and the Cancer Institute (Tokyo, Japan). I later returned to Adelaide to establish a research program at the Hanson Centre for Cancer Research at IMVS (which eventually became SA Pathology). In 2009, together with Angel Lopez, I co-founded the Centre for Cancer Biology (CCB), which I co-directed for approximately 11 years.
My research has been continuously supported by national and international fellowships for over three decades. Trained as a biochemist, molecular biologist, and cell biologist, I am deeply passionate about science and discovery. My current research focuses on the molecular mechanisms of disease, particularly cancer. Our work has led to foundational discoveries in two major areas of contemporary biomedical sciences: 'Cell Death' and 'Ubiquitin-dependent protein modification'. Some key contributions include:
Identification of the Nedd genes, including one of the first mammalian caspases (Nedd2/caspase-2)
Discovery of the Nedd4 family of ubiquitin ligases
Discovery of Nedd8, a ubiquitin-like protein central to the now widely recognised process of Neddylation
Elucidation of the Drosophila cell death machinery, including the discovery of 4 of 7 caspases and both Bcl-2-like proteins
Identification of Ndfip1 and Ndfip2 as adaptors/regulators of ubiquitin ligases
Discovery of a novel autophagy-dependent cell death program during development
These findings have advanced our understanding of various human diseases, including cancer, cardiovascular conditions, and kidney disorders. Our research has been published in approximately 300 articles, cited over 68,000 times, with a current H-index of 105 (Google Scholar). I have delivered more than 250 invited talks and seminars at national and international forums. Over the course of my career, I’ve had the privilege of mentoring 30 postdoctoral scientists, 32 laboratory staff, and 25 PhD students.

Cancer biology

Cell death modalities

Ubiquitination

Disease models and mechanisms

Cellular and molecular biology

Extracellular Vesicles (EVs)

Date Institution name Country Title
University of Adelaide Australia PhD

Year Citation
2025 Shah, M. V., Hung, K., Baranwal, A., Kutyna, M. M., Al-Kali, A., Toop, C., . . . Hiwase, D. K. (2025). Evidence-based risk stratification of myeloid neoplasms harboring TP53 mutations. Blood Advances, 9(13), 3370-3380.
DOI Scopus6 WoS4 Europe PMC5
2025 Umargamwala, R., Nicolson, S., Manning, J., Carosi, J. M., Kumar, S., & Denton, D. (2025). Identification of new candidates regulating autophagy-dependent midgut degradation in Drosophila melanogaster. Cell Death Discovery, 11(181), 181-1-181-13.
DOI Scopus1 WoS1 Europe PMC1
2025 Shah, M. V., Hung, K., Baranwal, A., Wechalekar, G., Al-Kali, A., Toop, C. R., . . . Hiwase, D. (2025). Validation of the 5th edition of the World Health Organization and International Consensus Classification guidelines for TP53-mutated myeloid neoplasm in an independent international cohort. Blood Cancer Journal, 15(1), 88-1-88-11.
DOI Scopus2 WoS2 Europe PMC1
2025 Manning, J. A., Jesudason, S., Moretti, P. A. B., Pitson, S. M., Chou, A. S. Y., Shabbar, M., . . . Kumar, S. (2025). Nedd4-2 ablation in kidney improves glycaemic control in diabetic mice. Cell Death and Disease, 16(496), 1-23.
DOI Scopus1 WoS1 Europe PMC1
2025 Windley, S. P., Neirijnck, Y., Vidovic, D., Schwarz, Q., Kumar, S., Nef, S., & Wilhelm, D. (2025). NEDD4 promotes Sertoli cell proliferation and adult Leydig cell differentiation in the murine testis. Endocrinology, in press(9), 14 pages.
DOI Europe PMC1
2025 Shabbar, M., Manning, J., Lim, Y., Shah, S., Sinha, D., Nikolic, A., . . . Kumar, S. (2025). Phospholipid scramblase 1 (PLSCR1) is a novel substrate of NEDD4-2 (NEDD4L) mediated ubiquitination. Cell Death Discovery, 11(1, article no. 393), 1-11.
DOI Scopus1 WoS1
2025 Shah, S. S., Manning, J. A., Lim, Y., Sinha, D., Murthy, A. M. V., Ganesan, R., . . . Kumar, S. (2025). NEDD4L-mediated Gasdermin D and E ubiquitination regulates cell death and tissue injury.. Cell Death Differ, online, 1-18.
DOI
2024 Kumar, S., Sharma, U., Kumar, S., & Bhardwaj, R. K. (2024). CLINICO-THERAPEUTIC MANAGEMENT OF DYSTOCIA DUE TO ASCITES FETUS IN A MURRAH BUFFALO. Buffalo Bulletin, 43(2), 151-153.
DOI
2024 Vora, S., Andrew, A., Kumar, R. P., Nazareth, D., Bonfim-Melo, A., Lim, Y., . . . Gabrielli, B. (2024). Aurora B inhibitors promote RB hypophosphorylation and senescence independent of p53-dependent CDK2/4 inhibition. Cell Death and Disease, 15(11, article no. 810), 810-1-810-9.
DOI Scopus6 WoS6 Europe PMC4
2024 Carosi, J. M., Hein, L. K., Sandow, J. J., Dang, L. V. P., Hattersley, K., Denton, D., . . . Sargeant, T. J. (2024). Autophagy captures the retromer-TBC1D5 complex to inhibit receptor recycling. Autophagy, 20(4), 863-882.
DOI Scopus6 WoS6 Europe PMC10
2024 Nicolson, S., Manning, J. A., Lim, Y., Jiang, X., Kolze, E., Dayan, S., . . . Denton, D. (2024). The Drosophila ZNRF1/2 homologue, detour, interacts with HOPS complex and regulates autophagy. Communications Biology, 7(1), 183-1-183-24.
DOI Scopus5 WoS3 Europe PMC4
2024 Umargamwala, R., Manning, J., Dorstyn, L., Denton, D., & Kumar, S. (2024). Understanding Developmental Cell Death Using Drosophila as a Model System. Cells, 13(4), 347-1-347-16.
DOI Scopus3 WoS2 Europe PMC1
2024 Welsh, J. A., Goberdhan, D. C. I., O'Driscoll, L., Buzas, E. I., Witwer, K. W., & Kumar, S. (2024). Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches. Journal of Extracellular Vesicles, 13(2, article no. e12404), 1-84.
DOI Scopus2076 WoS1637 Europe PMC1980
2024 Dawar, S., Benitez, M. C., Lim, Y., Dite, T. A., Yousef, J. M., Thio, N., . . . Clemons, N. J. (2024). Caspase-2 protects against ferroptotic cell death. Cell Death and Disease, 15(3), 182-1-182-12.
DOI Scopus13 WoS12 Europe PMC11
2023 Anand, S., Nedeva, C., Chitti, S. V., Fonseka, P., Kang, T., Gangoda, L., . . . Mathivanan, S. (2023). The E3 ubiquitin ligase NEDD4 regulates chemoresistance to 5-fluorouracil in colorectal cancer cells by altering JNK signalling. Cell Death and Disease, 14(828), 828-1-828-11.
DOI Scopus9 WoS9 Europe PMC9
2023 Carosi, J. M., Denton, D., Kumar, S., & Sargeant, T. J. (2023). Receptor Recycling by Retromer. Molecular and Cellular Biology, 43(7), 317-334.
DOI Scopus15 WoS16 Europe PMC16
2023 Dagdeviren, S., Hoang, M. F., Sarikhani, M., Meier, V., Benoit, J. C., Okawa, M. C., . . . Lee, R. T. (2023). An Insulin-regulated Arrestin Domain Protein Controls Hepatic Glucagon Action. Journal of Biological Chemistry, 299(8), 105045-1-105045-16.
DOI Scopus7 WoS8 Europe PMC10
2023 Hiwase, D. K., Hahn, C. N., Tran, E. N. H., Chhetri, R., Baranwal, A., Al-Kali, A., . . . Shah, M. V. (2023). TP53 mutation in therapy-related myeloid neoplasm defines a distinct molecular subtype. Blood, 141(9), 1087-1091.
DOI Scopus30 WoS26 Europe PMC26
2023 Shah, M. V., Tran, E. N. H., Shah, S., Chhetri, R., Baranwal, A., Ladon, D., . . . Hiwase, D. K. (2023). TP53 mutation variant allele frequency of ≥10% is associated with poor prognosis in therapy-related myeloid neoplasms. Blood Cancer Journal, 13(1), 51-1-51-9.
DOI Scopus32 WoS32 Europe PMC30
2023 Vitale, I., Pietrocola, F., Guilbaud, E., Aaronson, S. A., Abrams, J. M., Adam, D., . . . Galluzzi, L. (2023). Apoptotic cell death in disease-Current understanding of the NCCD 2023. Cell Death and Differentiation, 30(5), 1097-1154.
DOI Scopus261 WoS242 Europe PMC228
2022 Kutyna, M. M., Kok, C. H., Lim, Y., Campbell, D., Paton, S., Thompson-Peach, C. A. L., . . . Hiwase, D. (2022). Senolytic Therapy Can Reverse Senescent Bone Marrow Stroma of Therapy-Related Myeloid Neoplasm. Blood, 140(Supplement 1), 9755-9756.
DOI
2022 Kumar, S., Dorstyn, L., & Lim, Y. (2022). The role of caspases as executioners of apoptosis. Biochemical Society Transactions, 50(1), 33-45.
DOI Scopus46 WoS42 Europe PMC37
2022 Windley, S. P., Mayère, C., McGovern, A. E., Harvey, N. L., Nef, S., Schwarz, Q., . . . Wilhelm, D. (2022). Loss of NEDD4 causes complete XY gonadal sex reversal in mice. Cell Death and Disease, 13(1), 75-1-75-10.
DOI Scopus5 WoS5 Europe PMC7
2022 Farooq, A. U., Gembus, K., Sandow, J. J., Webb, A., Mathivanan, S., Manning, J. A., . . . Kumar, S. (2022). K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis. Journal of Extracellular Vesicles, 11(2), e12188-1-e12188-15.
DOI Scopus14 WoS13 Europe PMC10
2022 Lohraseb, I., McCarthy, P., Secker, G., Marchant, C., Wu, J., Ali, N., . . . Schwarz, Q. (2022). Global ubiquitinome profiling identifies NEDD4 as a regulator of Profilin 1 and actin remodelling in neural crest cells. Nature Communications, 13(1), 1-18.
DOI Scopus5 WoS6 Europe PMC7
2022 Kutyna, M. M., Kok, C. H., Lim, Y., Tran, E. N. H., Campbell, D., Paton, S., . . . Hiwase, D. K. (2022). A senescence stress secretome is a hallmark of therapy-related myeloid neoplasm stromal tissue occurring soon after cytotoxic exposure. Leukemia, 36(11), 2678-2689.
DOI Scopus17 WoS17 Europe PMC17
2022 Shah, M., Hahn, C. N., Tran, E. N. H., Sharplin, K. M., Chhetri, R., Baranwal, A., . . . Hiwase, D. (2022). <i>TP53</i> Mutation Status Defines a Distinct Clinicopathological Entity of Therapy-Related Myeloid Neoplasm, Characterized By Genomic Instability and Extremely Poor Outcome. BLOOD, 140(Supplement 1), 9798-9799.
DOI WoS2
2021 Lim, Y., Dorstyn, L., & Kumar, S. (2021). The p53-caspase-2 axis in the cell cycle and DNA damage response. Experimental and Molecular Medicine, 53(4), 517-527.
DOI Scopus44 WoS40 Europe PMC36
2021 Manning, J. A., Shah, S. S., Nikolic, A., Henshall, T. L., Khew-Goodall, Y., & Kumar, S. (2021). The ubiquitin ligase NEDD4-2/NEDD4L regulates both sodium homeostasis and fibrotic signaling to prevent end-stage renal disease. Cell Death and Disease, 12(4), 398-1-398-16.
DOI Scopus19 WoS18 Europe PMC14
2021 Sheng, J., Kohno, S., Okada, N., Okahashi, N., Teranishi, K., Matsuda, F., . . . Takahashi, C. (2021). Treatment of retinoblastoma 1-intact hepatocellular carcinoma with cyclin-dependent kinase 4/6 inhibitor combination therapy. Hepatology, 74(4), 1971-1993.
DOI Scopus33 WoS32 Europe PMC30
2021 Foot, N. J., Gonzalez, M. B., Gembus, K., Fonseka, P., Sandow, J. J., Nguyen, T. T., . . . Kumar, S. (2021). Arrdc4‐dependent extracellular vesicle biogenesis is required for sperm maturation. Journal of Extracellular Vesicles, 10(8), e12113-1-e12113-21.
DOI Scopus22 WoS23 Europe PMC20
2021 Klionsky, D. J., Petroni, G., Amaravadi, R. K., Baehrecke, E. H., Kumar, S., & Pietrocola, F. (2021). Autophagy in major human diseases. EMBO Journal, 40(19, article no. e108863), 1-63.
DOI Scopus1231 WoS1141 Europe PMC1077
2021 Carosi, J. M., Nguyen, T. N., Lazarou, M., Kumar, S., & Sargeant, T. J. (2021). ATG8ylation of proteins: a way to cope with cell stress?. The Journal of Cell Biology, 220(11), 1-4.
DOI Scopus16 WoS15 Europe PMC21
2021 Xu, T., Nicolson, S., Sandow, J. J., Dayan, S., Jiang, X., Manning, J. A., . . . Denton, D. (2021). Cp1/cathepsin L is required for autolysosomal clearance in Drosophila. Autophagy, 17(10), 2734-2749.
DOI Scopus12 WoS13 Europe PMC16
2021 Shah, S. S., & Kumar, S. (2021). Adaptors as the regulators of HECT ubiquitin ligases. Cell Death Differ, 28(2), 455-472.
DOI Scopus28 WoS29 Europe PMC30
2021 Carosi, J. M., Denton, D., Kumar, S., & Sargeant, T. J. (2021). Retromer dysfunction at the nexus of tauopathies. Cell Death and Differentiation, 28(3), 884-889.
DOI Scopus15 WoS13 Europe PMC15
2021 Klionsky, D. J., Abdel Aziz, A. K., Abdelfatah, S., Abdellatif, M., Kumar, S., & Tong, C. K. (2021). Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy, 17(1), 1-382.
DOI Scopus2024 WoS1912 Europe PMC1899
2021 Lim, Y., De Bellis, D., Sandow, J. J., Capalbo, L., D'Avino, P. P., Murphy, J. M., . . . Kumar, S. (2021). Phosphorylation by Aurora B kinase regulates caspase-2 activity and function.. Cell Death and Differentiation, 28(1), 349-366.
DOI Scopus25 WoS24 Europe PMC24
2021 Carosi, J. M., Hein, L. K., van den Hurk, M., Adams, R., Milky, B., Singh, S., . . . Sargeant, T. J. (2021). Retromer regulates the lysosomal clearance of MAPT/tau. Autophagy, 17(9), 2217-2237.
DOI Scopus30 WoS34 Europe PMC35
2021 Rather, T. A., Kumar, S., & Khan, J. A. (2021). Using machine learning to predict habitat suitability of sloth bears at multiple spatial scales. Ecological Processes, 10(1).
DOI Scopus22
2021 Kumar, S., Sharma, U., Kumar, S., & Dwivedi, D. K. (2021). Successful management of dystocia due to relative oversized fetus in a murrah buffalo. Buffalo Bulletin, 40(1), 195-198.
2021 Rather, T. A., Kumar, S., & Khan, J. A. (2021). Density estimation of tiger and leopard using spatially explicit capture-recapture framework. Peerj, 9, e10634.
DOI Scopus14
2021 Kumar, S., Kumar, S., Sharma, U., Pandey, A. K., & Bhardwaj, R. K. (2021). THERAPEUTIC MANAGEMENT OF POSTPARTUM CERVICO-VAGINAL PROLAPSE IN A MURRAH BUFFALO. Applied Biological Research, 23(4), 396-397.
DOI
2020 Rather, T. A., Tajdar, S., Kumar, S., & Khan, J. A. (2020). Seasonal variation in the diet of sloth bears in Bandhavgarh Tiger Reserve, Madhya Pradesh, India. Ursus, 2020(31e12), 1-8.
DOI Scopus10
2020 Rather, T. A., Kumar, S., & Khan, J. A. (2020). Multi-scale habitat selection and impacts of climate change on the distribution of four sympatric meso-carnivores using random forest algorithm. Ecological Processes, 9(1), 9 pages.
DOI Scopus29 WoS3 Europe PMC3
2020 Rather, T. A., Kumar, S., & Khan, J. A. (2020). Multi-scale habitat modelling and predicting change in the distribution of tiger and leopard using random forest algorithm. Scientific Reports, 10(1), 11473.
DOI Scopus86 Europe PMC27
2020 Murthy, A. M. V., Robinson, N., & Kumar, S. (2020). Crosstalk between cGAS-STING signaling and cell death. Cell Death and Differentiation, 27(11), 2989-3003.
DOI Scopus136 WoS129 Europe PMC122
2020 Hos, N. J., Fischer, J., Hos, D., Hejazi, Z., Calabrese, C., Ganesan, R., . . . Robinson, N. (2020). TRIM21 Is Targeted for Chaperone-Mediated Autophagy during Salmonella Typhimurium Infection.. J Immunol, 205(9), 2456-2467.
DOI Scopus26 WoS24 Europe PMC19
2020 Xu, T., Jiang, X., Denton, D., & Kumar, S. (2020). Ecdysone controlled cell and tissue deletion. Cell Death and Differentiation, 27(1), 1-14.
DOI Scopus46 WoS43 Europe PMC40
2020 Manning, J. A., Shah, S. S., Henshall, T. L., Nikolic, A., Finnie, J., & Kumar, S. (2020). Dietary sodium modulates nephropathy in Nedd4-2-deficient mice. Cell Death and Differentiation, 27(6), 1832-1843.
DOI Scopus11 WoS10 Europe PMC11
2020 Denton, D., O'Keefe, L., & Kumar, S. (2020). Drosophila as a model to understand autophagy deregulation in human disorders. Progress in Molecular Biology and Translational Science, 172, 375-409.
DOI Scopus7 WoS7 Europe PMC6
2020 Kulathunga, N., Kohno, S., Linn, P., Nishimoto, Y., Horike, S. -I., Zaraiskii, M. I., . . . Takahashi, C. (2020). Peripubertal high-fat diet promotes c-Myc stabilization in mammary gland epithelium. Cancer Science, 111(7), 2336-2348.
DOI Scopus4 WoS4 Europe PMC6
2020 Manning, J. A., Windley, S. P., Sandow, J. J., Shah, S. S., Western, P., Wilhelm, D., & Kumar, S. (2020). Identification of novel interacting partners of the NEDD4 ubiquitin ligase in mouse testis.. Journal of Proteomics, 223(103830), 103830-1-103830-8.
DOI Scopus3 WoS3 Europe PMC3
2020 Kohno, S., Linn, P., Nagatani, N., Watanabe, Y., Kumar, S., Soga, T., & Takahashi, C. (2020). Pharmacologically targetable vulnerability in prostate cancer carrying RB1-SUCLA2 deletion. Oncogene, 39(34), 5690-5707.
DOI Scopus13 WoS13 Europe PMC12
2019 Denton, D., & Kumar, S. (2019). Autophagy-dependent cell death. Cell Death and Differentiation, 26(4), 605-616.
DOI Scopus646 WoS617 Europe PMC561
2019 Dorstyn, L., Hackett-Jones, E., Nikolic, A., Norris, M. D., Lim, Y., Toubia, J., . . . Kumar, S. (2019). Transcriptome profiling of caspase-2 deficient EµMyc and Th-MYCN mouse tumors identifies distinct putative roles for caspase-2 in neuronal differentiation and immune signaling. Cell Death and Disease, 10(2), 56-1-56-16.
DOI Scopus7 WoS6 Europe PMC6
2019 Denton, D., Xu, T., Dayan, S., Nicolson, S., & Kumar, S. (2019). Crosstalk between Dpp and Tor signaling coordinates autophagy-dependent midgut degradation. Cell Death and Disease, 10(2), 111-1-111-8.
DOI Scopus5 WoS5 Europe PMC7
2019 Anand, S., Samuel, M., Kumar, S., & Mathivanan, S. (2019). Ticket to a bubble ride: cargo sorting into exosomes and extracellular vesicles. BBA - Proteins and Proteomics, 1867(12), 140203-1-140203-10.
DOI Scopus233 WoS214 Europe PMC196
2019 Rather, T. A., Tajdar, S., Kumar, S., & Khan, J. A. (2019). First photographic record of smooth coated otter (lutrogale perspicillata) in Bandhavgarh Tiger Reserve, Madhya pradesh, India. Iucn Ssc Otter Specialist Group Bulletin, 36(2), 93-97.
2019 Denton, D., Xu, T., Dayan, S., Nicolson, S., & Kumar, S. (2019). Dpp regulates autophagy-dependent midgut removal and signals to block ecdysone production. Cell Death and Differentiation, 26(4), 763-778.
DOI Scopus48 WoS47 Europe PMC44
2019 Xu, T., Denton, D., & Kumar, S. (2019). Hedgehog and Wingless signaling are not essential for autophagy-dependent cell death. Biochemical Pharmacology, 162(S1), 3-13.
DOI Scopus6 WoS6 Europe PMC7
2018 Denton, D., & Kumar, S. (2018). Ribophagy: New receptor discovered. Cell research, 28(7), 699-700.
DOI Scopus5 WoS4 Europe PMC4
2018 Manning, J. A., & Kumar, S. (2018). Physiological functions of nedd4-2: lessons from knockout mouse models. Trends in Biochemical Sciences, 43(8), 635-647.
DOI Scopus60 WoS63 Europe PMC57
2018 Anand, S., Foot, N., Ang, C. S., Gembus, K. M., Keerthikumar, S., Adda, C. G., . . . Kumar, S. (2018). Arrestin-domain containing protein 1 (Arrdc1) regulates the protein cargo and release of extracellular vesicles. Proteomics, 18(17), 1800266-1-1800266-6.
DOI Scopus57 WoS50 Europe PMC44
2018 Galluzzi, L., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Agostinis, P., . . . Manic, G. (2018). Molecular mechanisms of cell death: recommendations of the nomenclature committee on cell death 2018. Cell Death and Differentiation, 25(3), 486-541.
DOI Scopus5394 WoS4896 Europe PMC4619
2018 Dorstyn, L., Akey, C. W., & Kumar, S. (2018). New insights into apoptosome structure and function. Cell Death and Differentiation, 25(7), 1194-1208.
DOI Scopus181 WoS171 Europe PMC149
2018 Wilson, C. H., & Kumar, S. (2018). Caspases in metabolic disease and their therapeutic potential. Cell Death and Differentiation, 25(6), 1010-1024.
DOI Scopus70 WoS69 Europe PMC55
2018 Hopker, A., Pandey, N., Dhamorikar, A., Hopker, S., Gautam, P., Pandey, S., . . . Sargison, N. (2018). Correction: Delivery and evaluation of participatory education for animal keepers led by veterinarians and para-veterinarians around the Kanha Tiger Reserve, Madhya Pradesh, India (PLoS ONE (2018) 13: 8 (e0200999) DOI: 10.1371/journal.pone.0200999). Plos One, 13(8), e0203299.
DOI
2018 Hopker, A., Pandey, N., Dhamorikar, A., Hopker, S., Gautam, P., Pandey, S., . . . Sargison, N. (2018). Delivery and evaluation of participatory education for animal keepers led by veterinarians and para-veterinarians around the Kanha Tiger Reserve, Madhya Pradesh, India. Plos One, 13(8), e0200999.
DOI Scopus9 Europe PMC9
2018 Kumar, S., Sharma, U., Kumar, S., & Chakraborty, D. (2018). Different harvesting techniques for oocytes retrieval from sheep ovaries. Indian Veterinary Journal, 95(5), 33-35.
Scopus1
2018 Kumar, S., Sharma, U., Kumar, S., & Pandey, A. K. (2018). Oocytes recovery and seasonal effect in sheep. Indian Veterinary Journal, 95(5), 27-29.
2018 Lim, Y., De Bellis, D., Dorstyn, L., & Kumar, S. (2018). p53 accumulation following cytokinesis failure in the absence of caspase-2. Cell Death and Differentiation, 25(11), 2050-2052.
DOI Scopus11 WoS10 Europe PMC10
2018 Choi, S. (Ed.) (2018). Encyclopedia of Signaling Molecules.
DOI
2017 Galluzzi, L., Baehrecke, E. H., Ballabio, A., Boya, P., Kumar, S., & Kroemer, G. (2017). Molecular definitions of autophagy and related processes. The EMBO Journal, 36(13), 1811-1836.
DOI Scopus1406 WoS1310 Europe PMC1208
2017 Henshall, T., Manning, J., Alfassy, O., Goel, P., Boase, N., Kawabe, H., & Kumar, S. (2017). Deletion of Nedd4-2 results in progressive kidney disease in mice. Cell Death and Differentiation, 24(12), 2150-2160.
DOI Scopus31 WoS32 Europe PMC29
2017 Wilson, C., Nikolic, A., Kentish, S., Keller, M., Hatzinikolas, G., Dorstyn, L., . . . Kumar, S. (2017). Caspase-2 deficiency enhances whole-body carbohydrate utilisation and prevents high-fat diet-induced obesity. Cell Death and Disease, 8(10), e3136-1-e3136-12.
DOI Scopus14 WoS14 Europe PMC13
2017 Manning, J. A., Henshall, T. L., & Kumar, S. (2017). NEDD4-2-dependent control of Na⁺ homeostasis and renal disease. Cell cycle, 17(1), 1-2.
DOI Scopus8 WoS9 Europe PMC11
2017 Dawar, S., Lim, Y., Puccini, J., White, M., Thomas, P., Bouchier-Hayes, L., . . . Kumar, S. (2017). Caspase-2-mediated cell death is required for deleting aneuploid cells. Oncogene, 36(19), 2704-2714.
DOI Scopus55 WoS52 Europe PMC50
2017 Foot, N., Henshall, T., & Kumar, S. (2017). Ubiquitination and the regulation of membrane proteins. Physiological Reviews, 97(1), 253-281.
DOI Scopus206 WoS206 Europe PMC191
2017 Xu, T., Kumar, S., & Denton, D. (2017). Characterization of Autophagic Responses in Drosophila melanogaster. Methods in Enzymology, 588, 445-465.
DOI Scopus11 WoS11 Europe PMC9
2016 Foot, N., Gembus, K., MacKenzie, K., & Kumar, S. (2016). Ndfip2 is a potential regulator of the iron transporter DMT1 in the liver. Scientific Reports, 6(24045), 1-9.
DOI Scopus13 WoS12 Europe PMC11
2016 Mackenzie, K. D., Foot, N. J., Anand, S., Dalton, H. E., Chaudhary, N., Collins, B. M., . . . Kumar, S. (2016). Regulation of the divalent metal ion transporter via membrane budding. Cell Discovery, 2(1), 1-14.
DOI Scopus40 WoS39 Europe PMC35
2016 Camera, D., Coleman, H., Parkington, H., Jenkins, T., Pow, D., Boase, N., . . . Poronnik, P. (2016). Learning, memory and long-term potentiation are altered in Nedd4 heterozygous mice. Behavioural Brain Research, 303, 176-181.
DOI Scopus15 WoS15 Europe PMC14
2016 Yip, K., Kolesnikoff, N., Hauschild, N., Biggs, L., Lopez, A., Galli, S., . . . Grimbaldeston, M. (2016). The Nedd4-2/Ndfip1 axis is a negative regulator of IgE-mediated mast cell activation. Nature Communications, 7(article no. 13198), 13198-1-13198-14.
DOI Scopus31 WoS30 Europe PMC25
2016 Dawar, S., Shahrin, N., Sladojevic, N., D'Andrea, R., Dorstyn, L., Hiwase, D., & Kumar, S. (2016). Impaired haematopoietic stem cell differentiation and enhanced skewing towards myeloid progenitors in aged caspase-2-deficient mice. Cell Death and Disease, 7(12), e2509-1-e2509-9.
DOI Scopus26 WoS26 Europe PMC27
2016 Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Arozena, A. A., . . . Bagniewska-Zadworna, A. (2016). Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy, 12(1), 1-222.
DOI Scopus4570 WoS3817 Europe PMC4060
2016 Wilson, C. H., Dorstyn, L., & Kumar, S. (2016). Fat, sex and caspase-2. Cell Death and Disease, 7(e2125), 1-2.
DOI Scopus2 WoS2 Europe PMC1
2016 Shalini, S., Nikolic, A., Wilson, C., Puccini, J., Sladojevic, N., Finnie, J., . . . Kumar, S. (2016). Caspase-2 deficiency accelerates chemically induced liver cancer in mice. Cell Death and Differentiation, 23(10), 1727-1736.
DOI Scopus35 WoS32 Europe PMC28
2016 Wilson, C., Nikolic, A., Kentish, S., Shalini, S., Hatzinikolas, G., Page, A., . . . Kumar, S. (2016). Sex-specific alterations in glucose homeostasis and metabolic parameters during ageing of caspase-2-deficient mice. Cell Death Discovery, 2(16009), 16009-1-16009-10.
DOI Scopus15 WoS15 Europe PMC12
2016 Bhardwaz, A., Pandey, A. K., Sharma, U., Razzaque, W. A. A., Gupta, S. K., Kumar, S., & Kumar, S. (2016). Effect of cysteine hydrochloride on post thaw viability and acrosomal integrity of Jersey bull semen. Veterinary Practitioner, 17(2), 227-228.
Scopus2
2016 Kalsotra, R., Sharma, U., Kumar, S., & Kumar, S. (2016). Study of the incidence and factors affecting postpartum anestrus in Murrah buffaloes around Jammu region. Buffalo Bulletin, 35(4), 741-745.
Scopus1
2016 Kalsotra, R., Sharma, U., Kumar, S., Kumar, S., & Hussain, K. (2016). Studies on changes in hemato-biochemical and enzymatic profile in postpartum anestrus Murrah buffaloes with hormonal protocols. Buffalo Bulletin, 35(4), 733-739.
Scopus1
2016 Galluzzi, L., López-Soto, A., Kumar, S., & Kroemer, G. (2016). Caspases connect cell-death signaling to organismal homeostasis. Immunity, 44(2), 221-231.
DOI Scopus309 WoS283 Europe PMC237
2016 Meshram, I. I., Balakrishna, N., Sreeramakrishna, K., Rao, K. M., Kumar, R. H., Arlappa, N., . . . Laxmaiah, A. (2016). Trends in nutritional status and nutrient intakes and correlates of overweight/obesity among rural adult women (≥18-60 years) in India: National Nutrition Monitoring Bureau (NNMB) national surveys. Public Health Nutrition, 19(5), 767-776.
DOI Scopus20 Europe PMC18
2015 Kumar, A., Sharma, U., Pandey, A. K., Kumar, S., & Kumar, S. (2015). Induction of ovarian cyclicity and conception rate in postpartum anestrus buffaloes treated with different hormonal protocols. Buffalo Bulletin, 34(4), 441-445.
Scopus2
2015 Kumar, S., Saxena, A., Sagar, R., & Kumar, S. (2015). Study of serum mineral composition in post partum true anoestrus buffaloes. Buffalo Bulletin, 34(4), 397-399.
2015 Laxmaiah, A., Meshram, I. I., Arlappa, N., Balakrishna, N., Mallikharjuna Rao, K., Reddy, C. G., . . . Brahmam, G. N. V. (2015). Socio-economic & demographic determinants of hypertension & knowledge, practices & risk behaviour of tribals in India. Indian Journal of Medical Research, 142(May), 697-708.
DOI Scopus47 Europe PMC30
2015 Meshram, I. I., Kodavanti, M. R., Chitty, G. R., Manchala, R., Kumar, S., Kakani, S. K., . . . Ginnela Narsimhachary Veera, B. (2015). Influence of feeding practices and associated factors on the nutritional status of infants in rural areas of Madhya Pradesh State, India. Asia Pacific Journal of Public Health, 27(2), NP1345-NP1361.
DOI Scopus24 Europe PMC21
2015 Kalsotra, R., Sharma, U., Kumar, S., & Kumar, S. (2015). Induction of ovarian cyclicity and conception rate with different hormonal regimen in postpartum anestrus murrah buffaloes. Indian Veterinary Journal, 92(11), 20-23.
2015 Kumar, A., Sharma, U., Singh, R., Kumar, S., & Kumar, S. (2015). Changes in hemato-biochemical profile in postpartum anestrus Murrah buffaloes subjected to different hormonal protocols. Indian Veterinary Journal, 92(5), 50-52.
Scopus4
2015 Kodavalla, V., Meshram, I. I., Kodavanti, M. R., Reddy, C. G., Manchala, R., Kumar, S., . . . Veera, B. G. N. (2015). Nutrition profile of under-five year rural children and correlates of undernutrition in central India. Indian Journal of Community Health, 27(4), 486-496.
Scopus4
2015 Venkaiah, K., Kokku, S. B., Arlappa, N., Mallikharjun Rao, K., Gal Reddy, C., Kumar, S., . . . Brahm, G. N. V. (2015). Impact of chronic drought on nutritional status of the community in drought affected areas in India. Indian Journal of Community Health, 27(4), 479-485.
Scopus4
2015 Kumar, A., Sharma, U., Singh, R., Kumar, S., & Kumar, S. (2015). Studies on mineral profile of postpartum anestrus murrah buffaloes treated with different hormonal protocols. Indian Veterinary Journal, 92(8), 21-23.
Scopus1
2015 Kaur, M., Kumar, A., Kumar, S., Hakeem, H. R., & Gupta, S. (2015). Efficacy of carrot (daucus carrota) on quality characteristics of chicken nuggets. Indian Veterinary Journal, 92(4), 44-47.
Scopus2
2015 Zaman, M. I., Sharma, U., Taku, A. K., Kumar, S., & Kumar, S. (2015). Therapeutic studies and microbial profile in repeat breeding cows. Indian Veterinary Journal, 92(8), 56-58.
2015 Lim, Y., & Kumar, S. (2015). A single cut to pyroptosis. Oncotarget, 6(35), 36926-36927.
DOI Scopus25 WoS21 Europe PMC18
2015 Nicolson, S., Denton, D., & Kumar, S. (2015). Ecdysone-mediated programmed cell death in Drosophila. International Journal of Developmental Biology, 59(1-3), 23-32.
DOI Scopus42 WoS42 Europe PMC34
2015 Denton, D., & Kumar, S. (2015). Studying apoptosis in Drosophila. Cold Spring Harbor Protocols, 2015(7), 609-613.
DOI Scopus11 Europe PMC8
2015 Denton, D., & Kumar, S. (2015). Using synthetic peptide substrates to measure Drosophila caspase activity. Cold Spring Harbor Protocols, 2015(7), 671-674.
DOI Scopus2 Europe PMC1
2015 Denton, D., & Kumar, S. (2015). Analyzing the response of RNAI-treated drosophila cells to death stimuli by quantitative real-time polymerase chain reaction. Cold Spring Harbor Protocols, 2015(7), 666-671.
DOI Scopus3 Europe PMC3
2015 Denton, D., & Kumar, S. (2015). Immunostaining using an antibody against active caspase-3 to detect apoptotic cells in drosophila. Cold Spring Harbor Protocols, 6(6), 576-579.
DOI Scopus4 Europe PMC4
2015 Denton, D., & Kumar, S. (2015). Using the vital dye acridine orange to detect dying cells in drosophila. Cold Spring Harbor Protocols, 6(6), 572-574.
DOI Scopus11 Europe PMC8
2015 Xu, T., Nicolson, S., Denton, D., & Kumar, S. (2015). Distinct requirements of Autophagy-related genes in programmed cell death. Cell Death and Differentiation, 22(11), 1792-1802.
DOI Scopus65 WoS59 Europe PMC60
2015 Galluzzi, L., Pietrocola, F., Bravo-San Pedro, J., Amaravadi, R., Baehrecke, E., Cecconi, F., . . . Kroemer, G. (2015). Autophagy in malignant transformation and cancer progression. The EMBO Journal, 34(7), 856-880.
DOI Scopus1069 WoS1005 Europe PMC905
2015 Denton, D., Xu, T., & Kumar, S. (2015). Autophagy as a pro-death pathway. Immunology and Cell Biology, 93(1), 35-42.
DOI Scopus162 WoS154 Europe PMC132
2015 Goel, P., Manning, J., & Kumar, S. (2015). NEDD4-2 (NEDD4L): the ubiquitin ligase for multiple membrane proteins. Gene, 557(1), 1-10.
DOI Scopus145 WoS146 Europe PMC132
2015 Wilson, C., Shalini, S., Filipovska, A., Richman, T., Davies, S., Martin, S., . . . Kumar, S. (2015). Age-related proteostasis and metabolic alterations in Caspase-2-deficient mice. Cell Death & Disease, 6(1), e1597-1-e1597-12.
DOI Scopus38 WoS37 Europe PMC34
2015 Shalini, S., Dorstyn, L., Dawar, S., & Kumar, S. (2015). Old, new and emerging functions of caspases. Cell Death and Differentiation, 22(4), 526-539.
DOI Scopus1080 WoS1019 Europe PMC865
2015 Galluzzi, L., Bravo-San Pedro, J., Vitale, I., Aaronson, S., Abrams, J., Adam, D., . . . Oberst, A. (2015). Essential versus accessory aspects of cell death: recommendations of the NCCD 2015. Cell Death and Differentiation, 22(1), 58-73.
DOI Scopus865 WoS814 Europe PMC688
2015 Peintner, L., Dorstyn, L., Kumar, S., Aneichyk, T., Villunger, A., & Manzl, C. (2015). The tumor-modulatory effects of Caspase-2 and Pidd1 do not require the scaffold protein Raidd. Cell Death and Differentiation, 22(11), 1803-1811.
DOI Scopus23 WoS21 Europe PMC17
2015 Shalini, S., & Kumar, S. (2015). Caspase-2 and the oxidative stress response. Molecular & Cellular Oncology, 2(4), e1004956-1-e1004956-3.
DOI Scopus7 WoS7 Europe PMC4
2015 Denton, D., & Kumar, S. (2015). Terminal deoxynucleotidyl transferase (TdT)-mediated dutp nick-end labeling (TUNEL) for detection of apoptotic cells in Drosophila. Cold Spring Harbor Protocols, 2015(6), 568-571.
DOI Scopus19 Europe PMC14
2015 Boase, N., & Kumar, S. (2015). NEDD4: The founding member of a family of ubiquitin-protein ligases. Gene, 557(2), 113-122.
DOI Scopus128 WoS125 Europe PMC111
2014 Zaman, M. I., Sharma, U., Kumar, S., & Kumar, S. (2014). Incidence and factors infi uencing repeat breeding in crossbred cows. Indian Veterinary Journal, 91(5), 60-62.
2014 Kumar, S., Sharma, U., Kumar, S., & Soodan, J. S. (2014). Therapeutic management of prepartum cervico-vaginal prolapse in a crossbred Jersey cow. Indian Veterinary Journal, 91(4), 83-85.
Scopus1
2014 Sharma, U., Kumar, S., Kumar, S., & Soodan, J. S. (2014). Therapeutic management of post-partum uterine prolapse in a pluriparous Murrah buffalo. Veterinary Practitioner, 15(1), 126-127.
2014 Dorstyn, L., & Kumar, S. (2014). Caspase-2 protocols. Methods in Molecular Biology, 1133, 71-87.
DOI
2014 Dorstyn, L., Puccini, J., Nikolic, A., Shalini, S., Wilson, C., Norris, M., . . . Kumar, S. (2014). An unexpected role for caspase-2 in neuroblastoma. Cell Death and Disease, 5(8), e1383-1-e1383-9.
DOI Scopus21 WoS20 Europe PMC16
2014 Sandow, J., Dorstyn, L., O'Reilly, L., Tailler, M., Kumar, S., Strasser, A., & Ekert, P. (2014). ER stress does not cause upregulation and activation of caspase-2 to initiate apoptosis. Cell Death and Differentiation, 21(3), 475-480.
DOI Scopus50 WoS46 Europe PMC45
2014 Shalini, S., Puccini, J., Wilson, C., Finnie, J., Dorstyn, L., & Kumar, S. (2014). Caspase-2 protects against oxidative stress in vivo. Oncogene, 34(38), 4995-5002.
DOI Scopus30 WoS26 Europe PMC23
2014 Altin, J., Daley, S., Howitt, J., Rickards, H., Batkin, A., Horikawa, K., . . . Goodnow, C. (2014). Ndfip1 mediates peripheral tolerance to self and exogenous antigen by inducing cell cycle exit in responding CD4⁺ T cells. Proceedings of the National Academy of Sciences of the United States of America, 111(6), 2067-2074.
DOI Scopus20 WoS21 Europe PMC22
2014 Scheffner, M., & Kumar, S. (2014). Mammalian HECT ubiquitin-protein ligases: Biological and pathophysiological aspects. Biochimica et Biophysica Acta-Molecular Cell Research, 1843(1), 61-74.
DOI Scopus236 WoS225 Europe PMC217
2014 Camera, D., Boase, N., Kumar, S., Pow, D., & Poronnik, P. (2014). Subtle gait abnormalities in Nedd4 heterozygous mice. Behavioural Brain Research, 260, 15-24.
DOI Scopus10 WoS9 Europe PMC9
2014 Ekberg, J., Boase, N., Rychkov, G., Manning, J., Poronnik, P., & Kumar, S. (2014). Nedd4-2 (NEDD4L) controls intracellular Na⁺ -mediated activity of voltage-gated sodium channels in primary cortical neurons. Biochemical Journal, 457(1), 27-31.
DOI Scopus33 WoS33 Europe PMC32
2014 Sharma, U., Kumar, S., Kumar, S., Kushwaha, R. B., & Risum, N. S. (2014). Successful delivery of malposture fetus in protracted dystocia by forelimb amputation and detruncation in a crossbred heifer cow. Indian Veterinary Journal, 91(8), 94-96.
2014 Kumar, S., Kumar, S., Sharma, U., & Soodan, J. S. (2014). Delivery of fetus with nape presentation by mutation and forced traction in a primiparous crossbred cow. Indian Veterinary Journal, 91(7), 73-75.
Scopus1
2014 Kumar, S., Kumar, S., Sharma, U., Bhardwaj, H. R., & Pandey, A. K. (2014). Delivery of maldispositioned fetus by partial fetotomy in a primiparous mare. Indian Veterinary Journal, 91(1), 63-65.
2014 Dwivedi, D. K., Kushwaha, R. B., Sharma, A., & Kumar, S. (2014). Surgical drainage of a large abscess in the sternal area in a buffalo: A case report. Buffalo Bulletin, 33(1), 6-7.
2013 Laxmaiah, A., Arlappa, N., Balakrishna, N., Mallikarjuna Rao, K., Galreddy, C., Kumar, S., . . . Brahmam, G. N. V. (2013). Prevalence and determinants of micronutrient deficiencies among rural children of eight states in India. Annals of Nutrition and Metabolism, 62(3), 231-241.
DOI Scopus33 Europe PMC17
2013 Vishnu Vardhana Rao, M., Kumar, S., & Brahmam, G. N. V. (2013). A study of the geographical clustering of districts in Uttar Pradesh using nutritional anthropometric data of preschool children. Indian Journal of Medical Research, 137(1), 73-81.
Scopus8 Europe PMC3
2013 Kumar, S., Kumar, S., Sharma, U., & Soodan, J. S. (2013). Induced vaginal delivery of mummified fetus in a plouriparous crossbred cow. Indian Veterinary Journal, 90(12), 66-67.
Scopus3
2013 Kumar, S., Kumar, S., Sharma, U., & Gupta, A. (2013). Dystocia due to breech presentation in a crossbred cow. Indian Veterinary Journal, 90(12), 71-72.
2013 Kumar, S., Kumar, S., Sharma, U., & Pandey, A. K. (2013). Therapeutic management of hydroallantois in a Murrah buffalo. Indian Veterinary Journal, 90(8), 84-85.
Scopus1
2013 Denton, D., Aung Htut, M., & Kumar, S. (2013). Developmentally programmed cell death in Drosophila. Biochimica et Biophysica Acta-Molecular Cell Research, 1833(12), 3499-3506.
DOI Scopus64 WoS63 Europe PMC51
2013 Wiszniak, S., Kabbara, S., Lumb, R., Scherer, M., Secker, G., Harvey, N., . . . Schwarz, Q. (2013). The ubiquitin ligase Nedd4 regulates craniofacial development by promoting cranial neural crest cell survival and stem-cell like properties. Developmental Biology, 383(2), 186-200.
DOI Scopus25 WoS28 Europe PMC29
2013 Puccini, J., Dorstyn, L., & Kumar, S. (2013). Caspase-2 as a tumour suppressor. Cell Death and Differentiation, 20(9), 1133-1139.
DOI Scopus87 WoS84 Europe PMC69
2013 Puccini, J., Shalini, S., Voss, A., Gatei, M., Wilson, C., Hiwase, D., . . . Kumar, S. (2013). Loss of caspase-2 augments lymphomagenesis and enhances genomic instability in Atm-deficient mice. Proceedings of the National Academy of Sciences of the United States of America, 110(49), 19920-19925.
DOI Scopus62 WoS57 Europe PMC55
2013 Denton, D., Aung Htut, M., Lorensuhewa, N., Nicholson, S., Zhu, W., Mills, K., . . . Kumar, S. (2013). UTX coordinates steroid hormone-mediated autophagy and cell death. Nature Communications, 4(2916), 1-11.
DOI Scopus53 WoS48 Europe PMC37
2013 Puccini, J., Dorstyn, L., & Kumar, S. (2013). Genetic background and tumour susceptibility in mouse models. Cell Death and Differentiation, 20(7), 964.
DOI Scopus13 WoS13 Europe PMC13
2013 Liu, P., Xu, N., Malyukova, A., Scarlett, C., Sun, Y., Zhang, X., . . . Liu, T. (2013). The histone deacetylase SIRT2 stabilizes Myc oncoproteins. Cell Death and Differentiation, 20(3), 503-514.
DOI Scopus193 WoS173 Europe PMC161
2013 Ronzaud, C., Loffing-Cueni, D., Hausel, P., Debonneville, A., Malsure, S., Fowler-Jaeger, N., . . . Staub, O. (2013). Renal tubular NEDD4-2 deficiency causes NCC-mediated salt-dependent hypertension. Journal of Clinical Investigation, 123(2), 657-665.
DOI Scopus125 WoS127 Europe PMC108
2012 Garrick, M., Zhao, L., Roth, J., Jiang, H., Feng, J., Foot, N., . . . Garrick, L. (2012). Isoform specific regulation of divalent metal (ion) transporter (DMT1) by proteasomal degradation. Biometals, 25(4), 787-793.
DOI Scopus38 WoS34 Europe PMC30
2012 Denton, D., & Kumar, S. (2012). Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy, 8(4), 445-544.
DOI Scopus2981 WoS2665 Europe PMC2655
2012 Shalini, S., Dorstyn, L., Wilson, C., Puccini, J., Ho, L., & Kumar, S. (2012). Impaired antioxidant defence and accumulation of oxidative stress in caspase-2-deficient mice. Cell Death and Differentiation, 19(8), 1370-1380.
DOI Scopus78 WoS69 Europe PMC62
2012 Dorstyn, L., Puccini, J., Wilson, C., Shalini, S., Nicola, M., Moore, S., & Kumar, S. (2012). Caspase-2 deficiency promotes aberrant DNA-damage response and genetic instability. Cell Death and Differentiation, 19(8), 1288-1298.
DOI Scopus90 WoS88 Europe PMC81
2012 Denton, D., Chang, T., Nicolson, S., Shravage, B., Simin, R., Baehrecke, E., & Kumar, S. (2012). Relationship between growth arrest and autophagy in midgut programmed cell death in Drosophila. Cell Death and Differentiation, 19(8), 1299-1307.
DOI Scopus65 WoS62 Europe PMC63
2012 Howitt, J., Lackovic, J., Low, L., Naguib, A., Macintyre, A., Goh, C., . . . Tan, S. (2012). Ndfip1 regulates nuclear Pten import in vivo to promote neuronal survival following cerebral ischemia. Journal of Cell Biology, 196(1), 29-36.
DOI Scopus92 WoS89 Europe PMC88
2012 Galluzzi, L., Vitale, I., Abrams, J., Alnemri, E., Baehrecke, E., Blagosklonny, M., . . . Kroemer, G. (2012). Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012. Cell Death and Differentiation, 19(1), 107-120.
DOI Scopus2160 WoS1982 Europe PMC1752
2012 Denton, D., Nicolson, S., & Kumar, S. (2012). Cell death by autophagy: facts and apparent artefacts. Cell Death and Differentiation, 19(1), 87-95.
DOI Scopus350 WoS337 Europe PMC299
2012 Anil Kumar, P., Kumar, S., Mutha Rao, M., Sharma, U., Kumar, S., & Gupta, S. K. (2012). Pervaginal delivery of ascites foetus in buffalo-A case report. Veterinary Practitioner, 13(2), 335.
2012 Kumar, S., Sharma, U., Pandey, A. K., Agrawal, S., Kushwaha, R. B., & Tripathi, A. K. (2012). Hydroallantois in buffalo: A case report. Buffalo Bulletin, 31(2), 67-69.
Scopus3
2011 Boase, N., Rychkov, G., Townley, S., Dinudom, A., Candi, E., Voss, A., . . . Cook, D. (2011). Respiratory distress and perinatal lethality in Nedd4-2-deficient mice. Nature Communications, 2(1), 1-9.
DOI Scopus84 WoS79 Europe PMC74
2011 Dalton, H., Denton, D., Foot, N., Ho, K., Mills, K., Brou, C., & Kumar, S. (2011). Drosophila Ndfip is a novel regulator of Notch signaling. Cell Death and Differentiation, 18(7), 1150-1160.
DOI Scopus19 WoS20 Europe PMC24
2011 Lee, I., Song, S., Campbell, C., Kumar, S., Cook, D., & Dinudom, A. (2011). Regulation of the epithelial Na⁺ channel by the RH domain of G protein-coupled receptor kinase, GRK2, and Gαq/11. Journal of Biological Chemistry, 286(22), 19259-19269.
DOI Scopus13 WoS11 Europe PMC11
2011 Yuan, S., Yu, X., Topf, M., Dorstyn, L., Kumar, S., Ludtke, S., & Akey, C. (2011). Structure of the Drosophila apoptosome at 6.9 Å resolution. Structure, 19(1), 128-140.
DOI Scopus71 WoS65 Europe PMC58
2011 Foot, N., Leong, Y., Dorstyn, L., Dalton, H., Ho, K., Zhao, L., . . . Kumar, S. (2011). Ndfip1-deficient mice have impaired DMT1 regulation and iron homeostasis. Blood, 117(2), 638-646.
DOI Scopus41 WoS39 Europe PMC40
2011 Sinha, G. K., Mehra, R. K., & Kumar, S. (2011). Synthesis of Some Nitrogen Mustards (Mannich Bases). ORIENTAL JOURNAL OF CHEMISTRY, 27(3), 1261-1264.
WoS1
2010 Manning, J., & Kumar, S. (2010). A potential role for NEDD1 and the centrosome in senescence of mouse embryonic fibroblasts. Cell Death & Disease, 1(4), E35-1-E35-8.
DOI Scopus29 WoS31 Europe PMC33
2010 Hiwase, D., White, D., Powell, J., Saunders, V., Zrim, S., Frede, A., . . . Hughes, T. (2010). Blocking cytokine signaling along with intense Bcr-Abl kinase inhibition induces apoptosis in primary CML progenitors. Leukemia, 24(4), 771-778.
DOI Scopus48 WoS42 Europe PMC40
2010 Denton, D., Shravage, B., Simin, R., Baehrecke, E., & Kumar, S. (2010). Larval midgut destruction in Drosophila: Not dependent on caspases but suppressed by the loss of autophagy. Autophagy, 6(1), 163-165.
DOI Scopus54 WoS51 Europe PMC40
2010 Manning, J., Shalini, S., Risk, J., Day, C., & Kumar, S. (2010). A direct interaction with NEDD1 regulates γ-tubulin recruitment to the centrosome. PLoS One, 5(3), 1-12.
DOI Scopus39 WoS41 Europe PMC40
2010 Manning, J., Lewis, M., Koblar, S., & Kumar, S. (2010). An essential function for the centrosomal protein NEDD1 in zebrafish development. Cell Death and Differentiation, 17(8), 1302-1314.
DOI Scopus13 WoS13 Europe PMC14
2010 Kumar, S., Saxena, A., & Ramsagar. (2010). Comparative studies on metabolic profile of anestrous and normal cyclic murrah buffaloes. Buffalo Bulletin, 29(1), 7-11.
Scopus18
2009 Kumar, S., & Saini, R. (2009). CFD based performance analysis of a solar air heater duct provided with artificial roughness. Renewable energy, 34(5), 1285-1291.
DOI Scopus222 WoS179
2009 Arlappa, N., Venkaiah, K., Rao, K. M., Reddy, C. G., Kumar, S. S., Ravindranath, M., . . . Vijayaraghavan, K. (2009). Prevalence of chronic energy deficiency in rural-dwelling older indian adults during a period of severe drought. Journal of Nutrition for the Elderly, 28(3), 301-312.
DOI Scopus14 Europe PMC13
2009 Kumar, S. (2009). Caspase 2 in apoptosis, the DNA damage response and tumour suppression: enigma no more?. Nature Reviews. Cancer, 9(12), 897-903.
DOI Scopus124 WoS125 Europe PMC109
2009 Denton, D., Shravage, B., Simin, R., Mills, K., Berry, D., Baehrecke, E., & Kumar, S. (2009). Autophagy, not apoptosis, is essential for midgut cell death in Drosophila. Current Biology, 19(20), 1741-1746.
DOI Scopus327 WoS320 Europe PMC274
2009 Kumar, S., & Dorstyn, L. (2009). Analysing caspase activation and caspase activity in apoptotic cells. Methods in Molecular Biology, 559, 3-17.
DOI Scopus17 Europe PMC11
2009 Howitt, J., Putz, U., Lackovic, J., Doan, A., Dorstyn, L., Cheng, H., . . . Tan, S. (2009). Divalent metal transporter 1 (DMT1) regulation by Ndfip1 prevents metal toxicity in human neurons. Proceedings of the National Academy of Sciences of the United States of America, 106(36), 15489-15494.
DOI Scopus103 WoS101 Europe PMC95
2009 Yang, B., & Kumar, S. (2009). Nedd4 and Nedd4-2: closely related ubiquitin-protein ligases with distinct physiological functions. Cell Death and Differentiation, 17(1), 68-77.
DOI Scopus194 WoS192 Europe PMC184
2009 Rotin, D., & Kumar, S. (2009). Physiological functions of the HECT family of ubiquitin ligases. Nature Reviews. Molecular Cell Biology, 10(6), 398-409.
DOI Scopus894 WoS860 Europe PMC824
2009 Ho, L., Taylor, R., Dorstyn, L., Cakouros, D., Bouillet, P., & Kumar, S. (2009). A tumor suppressor function for caspase-2. Proceedings of the National Academy of Sciences of the United States of America, 106(13), 5336-5341.
DOI Scopus152 WoS142 Europe PMC136
2009 Lee, I., Campbell, C., Song, S., Day, M., Kumar, S., Cook, D., & Dinudom, A. (2009). The Activity of the Epithelial Sodium Channels Is Regulated by Caveolin-1 via a Nedd4-2-dependent Mechanism. Journal of Biological Chemistry, 284(19), 12663-12669.
DOI Scopus50 WoS45 Europe PMC43
2009 Kochetkova, M., Kumar, S., & McColl, S. (2009). Chemokine receptors CXCR4 and CCR7 promote metastasis by preventing anoikis in cancer cells. Cell Death and Differentiation, 16(5), 664-673.
DOI Scopus87 WoS83 Europe PMC74
2009 Kroemer, G., Galluzzi, L., Vandenabeele, P., Abrams, J., Kumar, S., & Melino, G. (2009). Classification of cell death : recommendations of the Nomenclature Committee on Cell Death 2009. Cell death and differentiation, 16(1), 3-11.
DOI Scopus2485 WoS2360 Europe PMC1944
2009 Galluzzi, L., Aaronson, S. A., Abrams, J., Alnemri, E. S., Andrews, D. W., Baehrecke, E. H., . . . Kroemer, G. (2009). Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes. Cell Death and Differentiation, 16(8), 1093-1107.
DOI Scopus599 WoS551 Europe PMC475
2009 Hiwase, D., White, D., Saunders, V., Kumar, S., Melo, J., & Hughes, T. (2009). Short-term intense Bcr-Abl kinase inhibition with nilotinib is adequate to trigger cell death in BCR-ABL<sup>+</sup> cells. Leukemia, 23(6), 1205-1206.
DOI Scopus17 WoS16 Europe PMC13
2009 Dorstyn, L., & Kumar, S. (2009). Putative functions of caspase-2. F1000 biology reports, 1(96), 1-5.
DOI Europe PMC2
2008 Ho, L., Read, S., Dorstyn, L., Lambrusco, L., & Kumar, S. (2008). Capase-2 is required for cell death induced by cytoskeletal disruption. Oncogene, 27(24), 3393-3404.
DOI Scopus111 WoS104 Europe PMC102
2008 Hiwase, D., Saunders, V., Hewett, D., Frede, A., Zrim, S., Dang, P., . . . White, D. (2008). Dasatinib cellular uptake and efflux in chronic myeloid leukemia cells: therapeutic implications. Clinical Cancer Research, 14(12), 3881-3888.
DOI Scopus168 WoS152 Europe PMC140
2008 Foot, N., Dalton, H., Shearwin-Whyatt, L., Dorstyn, L., Tan, S., Yang, B., & Kumar, S. (2008). Regulation of the divalent metal ion transporter DMT1 and iron homeostasis by a ubiquitin-dependent mechanism involving Ndfips and WWP2. Blood, 112(10), 4268-4275.
DOI Scopus125 WoS119 Europe PMC114
2008 Cao, X., Lill, N., Boase, N., Shi, P., Croucher, D., Shan, H., . . . Yang, B. (2008). Nedd4 controls animal growth by regulating IGF-1 signaling. Science Signaling, 1(38), 1-10.
DOI Scopus142 WoS136 Europe PMC132
2008 Putz, U., Howitt, J., Lackovic, J., Foot, N., Kumar, S., Silke, J., & Tan, S. (2008). Nedd4 Family-interacting Protein 1 (Ndfip1) Is Required for the Exosomal Secretion of Nedd4 Family Proteins. Journal of Biological Chemistry, 283(47), 32621-32627.
DOI Scopus146 WoS138 Europe PMC128
2008 He, Y., Hryciw, D., Carroll, M., Myers, S., Whitbread, A., Kumar, S., . . . Hooper, J. (2008). The ubiquitin-protein ligase Nedd4-2 differentially interacts with and regulates members of the Tweety family of chloride ion channels. Journal of Biological Chemistry, 283(35), 24000-24010.
DOI Scopus29 WoS30 Europe PMC27
2008 Cakouros, D., Mills, K., Denton, D., Paterson, A., Daish, T., & Kumar, S. (2008). dLKR/SDH regulates hormone-mediated histone arginine methylation and transcription of cell death genes. Journal of Cell Biology, 182(3), 481-495.
DOI Scopus26 WoS25 Europe PMC21
2008 Denton, D., Mills, K., & Kumar, S. (2008). Methods and protocols for studying cell death in Drosophila. Methods in Enzymology, 446, 17-37.
DOI Scopus32 WoS31 Europe PMC26
2008 Schuetz, F., Kumar, S., Poronnik, P., & Adams, D. (2008). Regulation of the voltage-gated K⁺ channels KCNQ2/3 and KCNQ3/5 by serum- and glucocorticoid-regulated kinase-1. American Journal of Physiology-Cell Physiology, 295(1), C73-C80.
DOI Scopus25 WoS24 Europe PMC25
2008 Manning, J., Colussi, P., Koblar, S., & Kumar, S. (2008). Nedd1 expression as a marker of dynamic centrosomal localization during mouse embryonic development. Histochemistry and Cell Biology, 129(6), 751-764.
DOI Scopus14 WoS15 Europe PMC14
2008 Dorstyn, L., & Kumar, S. (2008). A biochemical analysis of the activation of the Drosophila caspase DRONC. Cell Death and Differentiation, 15(3), 461-470.
DOI Scopus53 WoS48 Europe PMC43
2008 Kumar, S., Khan, J. A., & Pathak, B. J. (2008). Population structure, home range and food habits of Hanuman langur in Gir Lion Sanctuary and National Park, India. International Journal of Ecology and Environmental Sciences, 34(2), 165-173.
2008 Kumar, S., Khan, J. A., Khan, A., Musavi, A., Malik, P. K., Kushwaha, S. P. S., . . . Sarin, G. D. (2008). An ecological study in the buffer zone of the Corbett Tiger Reserve: Tiger abundance and cattle depredation. International Journal of Ecology and Environmental Sciences, 34(2), 133-140.
Scopus4
2008 Khan, J. A., Kumar, S., Khan, A., Musavi, A., Malik, P. K., Kushwaha, S. P. S., . . . Sarin, G. D. (2008). An ecological study in the buffer zone of the Corbett Tiger Reserve: Prey abundance and habitat conditions. International Journal of Ecology and Environmental Sciences, 34(2), 121-131.
Scopus4
2007 Dibbens, L., Ekberg, J., Taylor, I., Hodgson, B., Conroy, S., Lensink, I., . . . Poronnik, P. (2007). NEDD4-2 as a potential candidate susceptibility gene for epileptic photosensitivity. Genes, Brain and Behavior, 6(8), 750-755.
DOI Scopus48 WoS49 Europe PMC45
2007 Lee, I., Dinudom, A., Sanchez-Perez, A., Kumar, S., & Cook, D. (2007). Akt mediates the effect of insulin on epithelial sodium channels by inhibiting Nedd4-2. Journal of Biological Chemistry, 282(41), 29866-29873.
DOI Scopus129 WoS123 Europe PMC119
2007 Doumanis, J., Dorstyn, L., & Kumar, S. (2007). Molecular determinants of the subcellular localization of the Drosophila Bcl-2 homologues DEBCL and BUFFY. Cell Death and Differentiation, 14(5), 907-915.
DOI Scopus27 WoS27 Europe PMC23
2007 Sanchez-Perez, A., Kumar, S., & Cook, D. (2007). GRK2 interacts with and phosphorylates Nedd4 and Nedd4-2. Biochemical and Biophysical Research Communications, 359(3), 611-615.
DOI Scopus27 WoS24 Europe PMC23
2007 Kumar, S. (2007). Caspases and their many biological functions. Cell Death and Differentiation, 14(1), 1-2.
DOI Scopus16 WoS14
2007 Manning, J., & Kumar, S. (2007). NEDD1: Function in microtubule nucleation spindle assembly and beyond. International Journal of Biochemistry & Cell Biology, 39(1), 7-11.
DOI Scopus25 WoS25 Europe PMC24
2007 Kumar, S. (2007). Caspase function in programmed cell death. Cell Death and Differentiation, 14(1), 32-43.
DOI Scopus729 WoS699 Europe PMC589
2007 Ekberg, J., Schuetz, F., Boase, N. A., Conroy, S. J., Manning, J., Kumar, S., . . . Adams, D. J. (2007). Regulation of the voltage-gated K+ channels KCNQ2/3 and KCNQ3/5 by ubiquitination: Novel role for Nedd4-2. Journal of Biological Chemistry, 282(16), 12135-12142.
DOI Scopus81 WoS79 Europe PMC73
2006 Dorstyn, L., & Kumar, S. (2006). A cytochrome c-free fly apoptosome. Cell Death and Differentiation, 13(7), 1049-1051.
DOI Scopus26 WoS24 Europe PMC21
2006 Sang, Q., Kim, M., Kumar, S., Bye, N., Morganti-Kossmann, M., Gunnersen, J., . . . Tan, S. (2006). Nedd4-WW domain-binding protein 5 (Ndfip1) is associated with neuronal survival after acute cortical brain injury. Journal of Neuroscience, 26(27), 7234-7244.
DOI Scopus50 WoS49 Europe PMC44
2006 Shearwin-Whyatt, L., Dalton, H., Foot, N., & Kumar, S. (2006). Regulation of functional diversity within the Nedd4 family by accessory and adaptor proteins. Bioessays, 28(6), 617-628.
DOI Scopus142 WoS136 Europe PMC122
2006 Rauh, R., Dinudom, A., Fotia, A., Paulides, M., Kumar, S., Korbmacher, C., & Cook, D. (2006). Stimulation of the epithelial sodium channel (ENaC) by the serum- and glucocorticoid-inducible kinase (Sgk) involves the PY motifs of the channel but is independent of sodium feedback inhibition. Pflugers Archiv-European Journal of Physiology, 452(3), 290-299.
DOI Scopus32 WoS29 Europe PMC25
2006 Fotia, A., Cook, D., & Kumar, S. (2006). The ubiquitin-protein ligases Nedd4 and Nedd4-2 show similar ubiquitin-conjugating enzyme specificities. International Journal of Biochemistry & Cell Biology, 38(3), 472-479.
DOI Scopus25 WoS25 Europe PMC24
2006 Mills, K., Daish, T., Harvey, K., Pfleger, C., Hariharan, I., & Kumar, S. (2006). The Drosophila melanogaster Apaf-1 homologue ARK is required for most, but not all, programmed cell death. Journal of Cell Biology, 172(6), 809-815.
DOI Scopus62 WoS60 Europe PMC60
2006 Musavi, A., Khan, J. A., Kumar, S., Khan, A., Malik, P. K., Kushwaha, S. P. S., . . . Sarin, G. D. (2006). A study of Tiger human conflict in buffer zone of the Corbett Tiger Reserve: Protected area-people relationship. International Journal of Ecology and Environmental Sciences, 32(3), 241-257.
Scopus5
2005 Korten, Z., Cakouros, D., & Kumar, S. (2005). Ecdysone-mediated up-regulation of the effector caspase DRICE is required for hormone-dependent apoptosis in Drosophila cells. Journal of Biological Chemistry, 280(12), 11981-11986.
DOI Scopus59 WoS52 Europe PMC48
2005 Mills, K., Daish, T., & Kumar, S. (2005). The function of the Drosophila caspase DRONC in cell death and development. Cell Cycle, 4(6), 744-746.
DOI Scopus14 WoS13 Europe PMC11
2005 Umadevi, N., Kumar, S., & Narayana, N. (2005). Crystallization and preliminary X-ray diffraction studies of the WW4 domain of the Nedd4-2 ubiquitin-protein ligase. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications Online, 61(PN Part 12), 1084-1086.
DOI Scopus5 WoS5 Europe PMC5
2004 Shearwin-Whyatt, L., Brown, D., Wylie, F., Stow, J., & Kumar, S. (2004). N4WBP5A (Ndfip2), a Nedd4-interacting protein, localizes to multivesicular bodies and the Golgi, and has a potential role in protein trafficking. Journal of Cell Science, 117(16), 3679-3689.
DOI Scopus65 WoS64 Europe PMC58
2004 Kumar, S., & Cakouros, D. (2004). Transcriptional control of the core cell-death machinery. Trends in Biochemical Sciences, 29(4), 193-196.
DOI Scopus60 WoS60 Europe PMC52
2004 Hryciw, D., Ekberg, J., Lee, A., Lensink, I., Kumar, S., Guggino, W., . . . Poronnik, P. (2004). Nedd4-2 functionally interacts with CIC-5: Involvement in constitutive albumin endocytosis in proximal tubule cells. Journal of Biological Chemistry, 279(53), 54996-55007.
DOI Scopus81 WoS78 Europe PMC71
2004 Kumar, S. (2004). Migrate, differentiate, proliferate, or die: pleiotropic functions of an apical 'apoptotic caspase'. Signal Transduction Knowledge Environment (S T K E), 254(254), 1-4.
DOI Scopus21 Europe PMC11
2004 Daish, T., Mills, K., & Kumar, S. (2004). Drosophila caspase DRONC is required for specific developmental cell death pathways and stress-induced apoptosis. Developmental Cell, 7(6), 909-915.
DOI Scopus157 WoS150 Europe PMC139
2004 Chew, S., Akdemir, F., Chen, P., Lu, W., Mills, K., Daish, T., . . . Abrams, J. (2004). The apical caspase dronc governs programmed and unprogrammed cell death in Drosophila. Developmental Cell, 7(6), 897-907.
DOI Scopus136 WoS130 Europe PMC123
2004 Dorstyn, L., Mills, K., Lazebnik, Y., & Kumar, S. (2004). The two cytochrome c species, DC3 and DC4, are not required for caspase activation and apoptosis in Drosophila cells. Journal of Cell Biology, 167(3), 405-410.
DOI Scopus107 WoS105 Europe PMC98
2004 Baliga, B., Read, S., & Kumar, S. (2004). The biochemical mechanism of caspase-2 activation. Cell Death and Differentiation, 11(11), 1234-1241.
DOI Scopus178 WoS164 Europe PMC149
2004 Murdaca, J., Treins, C., Monthouel-Kartmann, M., Pontier-Brest, R., Kumar, S., Van Obberghen, E., & Giorgetti-Peraldi, S. (2004). Grb10 prevents Nedd4-mediated vascular endothelial growth factor receptor-2 degradation. Journal of Biological Chemistry, 279(25), 26754-26761.
DOI Scopus116 WoS115 Europe PMC102
2004 Ekert, P., Read, S., Silke, J., Marsden, V., Kaufmann, H., Hawkins, C., . . . Vaux, D. (2004). Apaf-1 and caspase-9 accelerate apoptosis, but do not determine whether factor-deprived or drug-treated cells die. Journal of Cell Biology, 165(6), 835-842.
DOI Scopus161 WoS151 Europe PMC134
2004 Fotia, A., Ekberg, J., Adams, D., Cook, D., Poronnik, P., & Kumar, S. (2004). Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2. Journal of Biological Chemistry, 279(28), 28930-28935.
DOI Scopus138 WoS135 Europe PMC126
2004 Dinudom, A., Fotia, A., Lefkowitz, R., Young, J., Kumar, S., & Cook, D. (2004). The kinase Grk2 regulates Nedd4/Nedd4-2-dependent control of epithelial Na+ channels. Proceedings of the National Academy of Sciences of the United States of America, 101(32), 11886-11890.
DOI Scopus75 WoS71 Europe PMC65
2004 Cakouros, D., Daish, T., & Kumar, S. (2004). Ecdysone receptor directly binds the promoter of the Drosophila caspase dronc, regulating its expression in specific tissues. Journal of Cell Biology, 165(5), 631-640.
DOI Scopus89 WoS88 Europe PMC74
2004 Cakouros, D., Daish, T., Mills, K., & Kumar, S. (2004). An arginine-histone methyltransferase, CARMER, coordinates ecdysone-mediated apoptosis in drosophila cells. Journal of Biological Chemistry, 279(18), 18467-18471.
DOI Scopus31 WoS31 Europe PMC30
2004 Kumar, S., Ahmed, F. A., Bhadwal, M. S., & Sharma, U. (2004). Biometry of female genitalia of Murrah Buffalo. Indian Veterinary Journal, 81(11), 1295-1296.
2003 Arlappa, N., Balakrishna, N., Kumar, S., Brahmam, G. N. V., & Vijayaraghavan, K. (2003). Diet and nutritional status of the elderly in rural India. Journal of Nutrition for the Elderly, 22(4), 35-52.
DOI Scopus5
2003 Baliga, B., & Kumar, S. (2003). Apaf-1/cytochrome c apoptosome: an essential initiator of caspase activation or just a sideshow?. Cell Death and Differentiation, 10(1), 16-18.
DOI Scopus97 WoS94 Europe PMC76
2003 Kim, T., Hung, C., Ling, M., Juang, J., He, L., Hardwick, J., . . . Wu, T. (2003). Enhancing DNA vaccine potency by coadministration of DNA encoding antiapoptotic proteins. Journal of Clinical Investigation, 112(1), 109-117.
DOI Scopus169 WoS156 Europe PMC130
2003 Quinn, L., Coombe, M., Mills, K., Daish, T., Colussi, P., Kumar, S., & Richardson, H. (2003). Buffy, a Drosophila Bcl-2 protein, has anti-apoptotic and cell cycle inhibitory functions. EMBO Journal, 22(14), 3568-3579.
DOI Scopus128 WoS117 Europe PMC110
2003 Daish, T., Cakouros, D., & Kumar, S. (2003). Distinct promoter regions regulate spatial and temporal expression of the Drosophila caspase dronc. Cell Death and Differentiation, 10(12), 1348-1356.
DOI Scopus32 WoS31 Europe PMC27
2003 Baliga, B., Colussi, P., Read, S., Dias, M., Jans, D., & Kumar, S. (2003). Role of prodomain in importin-mediated nuclear localization and activation of caspase-2. Journal of Biological Chemistry, 278(7), 4899-4905.
DOI Scopus92 WoS92 Europe PMC84
2002 Read, S., Baliga, B., Ekert, P., Vaux, D., & Kumar, S. (2002). A novel Apaf-1-independent putative caspase-2 activation complex. Journal of Cell Biology, 159(5), 739-745.
DOI Scopus150 WoS134 Europe PMC124
2002 Fotia, A., Dinudom, A., Shearwin, K., Koch, J. P., Korbmacher, C., Cook, D., & Kumar, S. (2002). The role of individual Nedd4-2 (KIAA0439) WW domains in binding and regulating epithelial sodium channels. FASEB Journal, 16(13), 70-91.
DOI Scopus92 WoS86 Europe PMC79
2002 Dorstyn, L., Read, S., Cakouros, D., Huh, J., Hay, B., & Kumar, S. (2002). The role of cytochrome c in caspase activation in Drosophila melanogaster cells. Journal of Cell Biology, 156(6), 1089-1098.
DOI Scopus172 WoS166 Europe PMC148
2002 Shcherbik, N., Kumar, S., & Haines, D. (2002). Substrate proteolysis is inhibited by dominant-negative Nedd4 and Rsp5 mutants harboring alterations in WW domain 1. Journal of Cell Science, 115(5), 1041-1048.
DOI Scopus18 WoS18 Europe PMC14
2002 Baliga, B., & Kumar, S. (2002). Role of BCL-2 family of proteins in malignancy. Hematological Oncology, 20(2), 63-74.
DOI Scopus87 WoS74 Europe PMC58
2002 Konstas, A., Shearwin-Whyatt, L., Fotia, A., Degger, B., Riccardi, D., Cook, D., . . . Kumar, S. (2002). Regulation of the epithelial sodium channel by N4WBP5A, a novel Nedd4/Nedd4-2-interacting protein. Journal of Biological Chemistry, 277(33), 29406-29416.
DOI Scopus87 WoS85 Europe PMC77
2002 Harvey, K., Shearwin-Whyatt, L., Fotia, A., Parton, R., & Kumar, S. (2002). N4WBP5, a potential target for ubiquitination by the Nedd4 family of proteins, is a novel golgi-associated protein. Journal of Biological Chemistry, 277(11), 9307-9317.
DOI Scopus108 WoS107 Europe PMC101
2002 Cakouros, D., Daish, T., Martin, D., Baehrecke, E., & Kumar, S. (2002). Ecdysone-induced expression of the caspase DRONC during hormone-dependent programmed cell death in Drosophila is regulated by Broad-Complex. Journal of Cell Biology, 157(6), 985-995.
DOI Scopus90 WoS87 Europe PMC76
2002 Richardson, H., & Kumar, S. (2002). Death to flies: Drosophila as a model system to study programmed cell death. Journal of Immunological Methods, 265(1-2), 21-38.
DOI Scopus92 WoS80 Europe PMC73
2002 O'Reilly, L., Ekert, P., Harvey, N., Marsden, V., Cullen, L., Vaux, D., . . . Kumar, S. (2002). Caspase-2 is not required for thymocyte or neuronal apoptosis even though cleavage of caspase-2 is dependent on both Apaf-1 and caspase-9. Cell Death and Differentiation, 9(8), 832-841.
DOI Scopus167 WoS159 Europe PMC146
2002 Kumar, S., & Vaux, D. (2002). A Cinderella caspase takes center stage. Science, 297(5585), 1290-1291.
DOI Scopus101 WoS99 Europe PMC81
2002 Laxmaiah, A., Mallikharjuna Rao, K., Brahmam, G. N. V., Kumar, S., Ravindranath, M., Kashinath, K., . . . Vijayaraghavan, K. (2002). Diet and nutritional status of rural preschool children in Punjab. Indian Pediatrics, 39(4), 331-338.
Scopus20 Europe PMC10
2001 Harvey, K., Dinudom, A., Cook, D., & Kumar, S. (2001). The Nedd4-like protein KIAA0439 is a potential regulator of the epithelial sodium channel. Journal of Biological Chemistry, 276(11), 8597-8601.
DOI Scopus141 WoS134 Europe PMC123
2001 Dinudom, A., Harvey, K., Komwatanat, P., Jolliffe, C., Young, J., Kumar, S., & Cook, D. (2001). Roles of the C termini of α-, β-, and γ-subunits of epithelial Na⁺ channels (ENaC) in regulating ENaC and mediating its inhibition by cytosolic Na⁺. Journal of Biological Chemistry, 276(17), 13744-13749.
DOI Scopus20 WoS20 Europe PMC17
2001 Shearwin-Whyatt, L., Baliga, B., Doumanis, J., & Kumar, S. (2001). Chimeric caspase molecules with potent cell killing activity in apoptosis-resistant cells. Biochemical and Biophysical Research Communications, 282(5), 1114-1119.
DOI Scopus5 WoS6 Europe PMC5
2001 Doumanis, J., Quinn, L., Richardson, H., & Kumar, S. (2001). STRICA, a novel Drosophila melanogaster caspase with an unusual serine/threonine-rich prodomain, interacts with DIAP1 and DIAP2. Cell Death and Differentiation, 8(4), 387-394.
DOI Scopus71 WoS67 Europe PMC60
2001 Harvey, N., Daish, T., Mills, K., Dorstyn, L., Quinn, L., Read, S., . . . Kumar, S. (2001). Characterization of the Drosophila caspase, DAMM. Journal of Biological Chemistry, 276(27), 25342-25350.
DOI Scopus76 WoS67 Europe PMC64
2000 Kumar, S. (2000). Cell death in the fly comes of age - Editorial. Cell Death and Differentiation, 7(11), 1021-1024.
2000 Quinn, L., Dorstyn, L., Mills, K., Colussi, P., Chen, P., Coombe, M., . . . Richardson, H. (2000). An essential role for the caspase dronc in developmentally programmed cell death in Drosophila. Journal of Biological Chemistry, 275(51), 40416-40424.
DOI Scopus136 WoS131 Europe PMC119
2000 Colussi, P., Quinn, L., Huang, D., Coombe, M., Read, S., Richardson, H., & Kumar, S. (2000). Debcl a proapoptotic Bcl-2 homologue is a component of the Drosophila melanogaster cell death machinery. Journal of Cell Biology, 148(4), 703-714.
DOI Scopus147 WoS137 Europe PMC125
2000 Jolliffe, C., Harvey, K., Haines, B., Parasivam, G., & Kumar, S. (2000). Identification of multiple proteins expressed in murine embryos as binding partners for the WW domains of the ubiquitin-protein ligase Nedd4. Biochemical Journal, 351(3), 557-565.
DOI Scopus97 WoS98 Europe PMC95
2000 Shearwin-Whyatt, L., Harvey, N., & Kumar, S. (2000). Subcellular localization and CARD-dependent oligomerization of the death adaptor RAIDD. Cell Death and Differentiation, 7(2), 155-165.
DOI Scopus51 WoS49 Europe PMC48
2000 Kumar, S., & Doumanis, J. (2000). The fly caspases. Cell Death and Differentiation, 7(11), 1039-1044.
DOI Scopus141 WoS129 Europe PMC113
2000 Kumar, S. (2000). Cell death in the fly comes of age. Cell Death and Differentiation, 7(11), 1021-1024.
DOI Scopus1 WoS1 Europe PMC1
2000 Kinoshita, A., Noda, M., & Kinoshita, M. (2000). Differential localization of septins in the mouse brain. Journal of Comparative Neurology, 428(2), 223-239.
DOI Scopus111 Europe PMC96
1999 Kumar, S. (1999). Regulation of caspase activation in apoptosis: implications in pathogenesis and treatment of disease.. Clinical and experimental pharmacology & physiology, 26(4), 295-303.
DOI Europe PMC42
1999 Colussi, P. A., & Kumar, S. (1999). Targeted disruption of caspase genes in mice: What they tell us about the functions of individual caspases in apoptosis. Immunology and Cell Biology, 77(1), 58-63.
DOI Scopus48 WoS50 Europe PMC45
1999 Kumar, S. (1999). Regulation of Caspase Activation in Apoptosis: Implications in Pathogenesis and Treatment of Disease. Clinical and Experimental Pharmacology and Physiology, 26(-), 295-303.
DOI Scopus55 WoS55
1999 Kumar, S. (1999). Mechanisms mediating caspase activation in cell death. Cell Death and Differentiation, 6(-), 1060-1066.
DOI Scopus195 WoS186 Europe PMC154
1999 Dorstyn, L., Read, S., Quinn, L., Richardson, H., & Kumar, S. (1999). DECAY, a novel Drosophila caspase related to mammalian Caspase-3 and Caspase-7. Journal of Biological Chemistry, 274(43), 30778-30783.
DOI Scopus113 WoS107 Europe PMC94
1999 Harvey, K., & Kumar, S. (1999). Nedd4-like proteins: an emerging family of ubiquitin-protein ligases implicated in diverse cellular functions. Trends in Cell Biology, 9(5), 166-169.
DOI Scopus182 WoS184 Europe PMC170
1999 Kumar, S., & Colussi, P. (1999). Prodomains - adaptors - oligomerization: the pursuit of caspase activation in apoptosis. Trends in Biochemical Sciences, 24(36161), 1-Apr.
DOI Scopus92 WoS83 Europe PMC65
1999 Morrione, A., Plant, P., Valentinist, B., Staub, O., Kumar, S., Rotin, D., & Baserga, R. (1999). mGrb10 Interacts with Nedd4. Journal of Biological Chemistry, 274(34), 24094-24099.
DOI Scopus92 WoS91 Europe PMC78
1999 Harvey, K., Dinudom, A., Komwatanat, P., Jolliffe, C., Day, M., Parasivam, G., . . . Kumar, S. (1999). All three WW domains of murine Nedd4 are involved in the regulation of epithelial sodium channels by intracellular Na⁺. Journal of Biological Chemistry, 274(18), 12525-12530.
DOI Scopus111 WoS109 Europe PMC99
1999 Shearwin-Whyatt, L., & Kumar, S. (1999). Caspases in developmental cell death. IUBMB Life, 48(2), 143-150.
DOI Scopus4 WoS4 Europe PMC2
1999 Dorstyn, L., Colussi, P., Quinn, L., Richardson, H., & Kumar, S. (1999). DRONC, an ecdysone-inducible Drosophila caspase. Proceedings of the National Academy of Sciences of the United States of America, 96(36251), 4307-4312.
DOI Scopus253 WoS248 Europe PMC211
1999 Ishibashi, H., Dinudom, A., Harvey, K., Kumar, S., Young, J., & Cook, D. (1999). Na+-H+ exchange in salivary secretory cells is controlled by an intracellular Na+ receptor. Proceedings of the National Academy of Sciences of the United States of America, 96(17), 9949-9953.
DOI Scopus29 WoS27 Europe PMC22
1998 Bird, C., Sutton, V., Sun, J., Hirst, C., Novak, A., Kumar, S., . . . Bird, P. (1998). Selective regulation of apoptosis: the cytoxic lymphocyte serpin, proteinase inhibitor 9 protects against granzyme B-mediated apoptosis without perturbing the FAS Cell death pathway. Molecular and Cellular Biology, 18(11), 6387-6398.
DOI Scopus266 WoS256 Europe PMC219
1998 Jans, D., Briggs, L., Jans, P., Froelich, C., Parasivam, G., Kumar, S., . . . Trapani, J. (1998). Nuclear targeting of the serine protease granzyme A (fragmentin-1). Journal of Cell Science, 111(17), 2645-2654.
DOI Scopus51 WoS45 Europe PMC34
1998 Colussi, P., Harvey, N., & Kumar, S. (1998). Prodomain-dependent neclear localisation of the caspase-2 (Nedd2) precursor: A novel fuction for a caspase prodomain. Journal of Biological Chemistry, 273(38), 24535-24542.
DOI Scopus143 WoS138 Europe PMC127
1998 Butt, A., Harvey, N., Parasivam, G., & Kumar, S. (1998). Dimerization and auto processing of the Nedd2 (caspase 2) precursor requires both the prodomain and the carboxyl-terminal regions. Journal of Biological Chemistry, 273(12), 6763-6768.
DOI Scopus100 WoS98 Europe PMC89
1998 Colussi, P., Harvey, N., Shearwin-Whyatt, L., & Kumar, S. (1998). Conversion of procaspase-3 to an autoactivating caspase by fusion to the caspase-2 predomain. Journal of Biological Chemistry, 273(41), 26566-26570.
DOI Scopus72 WoS70 Europe PMC60
1998 Harvey, K., Harvey, N., Michael, J., Parasivam, G., Waterhouse, N., Alnemri, E., . . . Kumar, S. (1998). Caspase-mediated cleavage of the ubiquitin-protein ligase Nedd4 during apoptosis. Journal of Biological Chemistry, 273(22), 13524-13530.
DOI Scopus63 WoS64 Europe PMC52
1998 Dinudom, A., Harvey, K., Komwatanat, P., Young, J., Kumar, S., & Cook, D. (1998). Nedd4 mediates control of an epithelial Na+ channel in salivary duct cells by cytosic Na+. Proceedings of the National Academy of Sciences of the United States of America, 95(12), 7169-7173.
DOI Scopus124 WoS127 Europe PMC110
1998 Kinoshita, A., Kinshita, M., Akiyama, H., Tomimoto, H., Akiguchi, I., Kumar, S., . . . Kimura, J. (1998). Identification of septins in neurofibrillary tangles in Alzheimers Disease. American Journal of Pathology, 153(5), 1551-1560.
DOI Scopus135 WoS128 Europe PMC117
1998 Waterhouse, N. J., Finucane, D. M., Green, D. R., Elce, J. S., Kumar, S., Alnemri, E. S., . . . Watters, D. J. (1998). Calpain activation is upstream of caspases in radiation-induced apoptosis. Cell Death and Differentiation, 5(12), 1051-1061.
DOI Scopus168 WoS161 Europe PMC131
1998 Harvey, N. L., & Kumar, S. (1998). The role of caspases in apoptosis.. Advances in Biochemical Engineering Biotechnology, 62, 107-128.
DOI Scopus48 Europe PMC30
1997 Kumar, S., Kinoshita, M., Dorstyn, L., & Noda, M. (1997). Origin, expression and possible functions of the two alternatively spliced forms of the mouse Nedd2 mRNA. Cell Death and Differentiation, 4(5), 378-387.
DOI Scopus28 WoS28
1997 Dorstyn, L., & Kumar, S. (1997). Differential inhibitory effects of CrmA, P35, IAP and three mammalian IAP homologues on apoptosis in NIH3T3 cells following various death stimuli. Cell Death and Differentiation, 4(7), 570-579.
DOI Scopus26 WoS26 Europe PMC22
1997 Kumar, S. (1997). The Bcl-2 family of proteins and activation of the ICE-CED-3 family of proteases: A balancing act in apoptosis?. Cell Death and Differentiation, 4(1), 2-3.
DOI Scopus20 WoS29 Europe PMC11
1997 Kinoshita, M., Kumar, S., Mizoguchi, A., Ide, C., Kinoshita, A., Haraguchi, T., . . . Noda, M. (1997). Nedd5, a mammalian septin, is a novel cytoskeletal component interacting with actin-based structures. Genes and Development, 11(12), 1535-1547.
DOI Scopus329 WoS324 Europe PMC286
1997 Kinoshita, M., Tomimoto, H., Kinoshita, A., Kumar, S., & Noda, M. (1997). Up-regulation of the Nedd2 gene encoding an ICE/Ced-3-like cysteine protease in the gerbil brain after transient global ischemia. Journal of Cerebral Blood Flow and Metabolism, 17(5), 507-514.
DOI Scopus65 WoS58 Europe PMC41
1997 Sun, J., Bottomley, S. P., Kumar, S., & Bird, P. I. (1997). Recombinant caspase-3 expressed in Pichia pastoris is fully activated and kinetically indistinguishable from the native enzyme. Biochemical and Biophysical Research Communications, 238(3), 920-924.
DOI Scopus31 WoS27 Europe PMC23
1997 Kumar, S., Harvey, K. F., Kinoshita, M., Copeland, N. G., Noda, M., & Jenkins, N. A. (1997). cDNA cloning, expression analysis, and mapping of the mouse Nedd4 gene. Genomics, 40(3), 435-443.
DOI Scopus136 WoS134 Europe PMC120
1997 Kinoshita, M. (1997). Characterization of a mammalian cell death gene Nedd2. Leukemia, 11(SUPPL. 3), 385-386.
Scopus14 Europe PMC6
1997 Harvey, N. L., Butt, A. J., & Kumar, S. (1997). Functional activation of Nedd2/ICH-1 (caspase-2) is an early process in apoptosis. Journal of Biological Chemistry, 272(20), 13134-13139.
DOI Scopus122 WoS127 Europe PMC101
1997 Kumar, S. (1997). The apoptotic cysteine protease CPP32. International Journal of Biochemistry and Cell Biology, 29(3), 393-396.
DOI Scopus71 WoS59 Europe PMC57
1997 Iversen, P., Hercus, T., Zacharakis, B., Woodcock, J., Stomski, F., Kumar, S., . . . Lopez, A. (1997). The apoptosis-inducing granulocyte-macrophage colony-stimulating factor (GM-CSF) analog E21R functions through specific regions of the heterodimeric GM-CSF receptor, and requires interleukin-1 beta converting enzyme-like proteases.. Journal of Biological Chemistry, 272(15), 9877-9883.
DOI Scopus12 WoS12 Europe PMC8
1996 Waterhouse, N., Kumar, S., Song, Q., Strike, P., Sparrow, L., Dreyfuss, G., . . . Watters, D. (1996). Heteronuclear ribonucleoproteins C1 ad C2, components of the spliceosome, are specific targets of interleukin 1β-converting enzyme-like proteases in apoptosis. Journal of Biological Chemistry, 271(46), 29335-29341.
DOI Scopus115 WoS105 Europe PMC88
1996 Song, Q., Burrows, S., Smith, G., Lees-Miller, S., Kumar, S., Chan, D., . . . Lavin, M. (1996). Interleukin-1β-converting enzyme-like protease cleaves DNA-dependent protein kinase in cytotoxic T cell killing. Journal of Experimental Medicine, 184(2), 619-626.
DOI Scopus53 WoS51 Europe PMC41
1996 Kumar, S., & Lavin, M. F. (1996). The ICE family of cysteine proteases as effectors of cell death. Cell Death and Differentiation, 3(3), 255-267.
Scopus159 WoS160 Europe PMC90
1996 Harvey, N., Trapani, J., Fernandes-Alnemri, T., Litwack, G., Alnemri, E., & Kumar, S. (1996). Processing of the Nedd2 precursor by ICE-like proteases and granzyme B. Genes to Cells, 1(7), 673-686.
DOI Scopus54 WoS57 Europe PMC44
1996 Wallers, P., Waterhouse, N., Kumar, S., Sparrow, L., Strike, P., & Lavin, M. (1996). Specific cleavage of hnRNP C proteins in apoptosis. Biochemical Society Transactions, 24(4), 565.
1996 Song, Q., Lees-Miller, S., Kumar, S., Zhang, N., Chan, D., Smith, G., . . . Lavin, M. (1996). DNA-dependent protein kinase catalytic subunit: a target for an ICE-like protease in apoptosis. EMBO Journal, 15(13), 3238-3246.
DOI Scopus332 WoS313 Europe PMC243
1995 Kumar, S. (1995). Inhibition of apoptosis by the expression of antisense Nedd2. FEBS Letters, 368(1), 69-72.
DOI Scopus54 WoS56 Europe PMC43
1995 Kumar, S., & Harvey, N. (1995). Role of multiple cellular proteases in the execution of programmed cell death. FEBS Letters, 375(3), 169-173.
DOI Scopus150 WoS149 Europe PMC99
1995 Takai, S., Yoshida, Y., Noda, M., Yamada, K., & Kumar, S. (1995). Assignment of the developmentally regulated gene NEDD1 to human chromosome 12922 by fluorescence in situ hybridisation. Human Genetics, 95(1), 96-98.
DOI Scopus5 WoS6 Europe PMC4
1995 Kumar, S., White, D., Takai, S., Turczynowicz, S., Juttner, C., & Hughes, T. (1995). Apoptosis regulatory gene NEDD2 maps to human chromosome segment 7934-35, a region frequently affected in haematological neoplasms. Human Genetics, 95(6), 641-644.
DOI Scopus41 WoS39 Europe PMC26
1995 Kumar, S. (1995). ICE-like proteases in apoptosis. Trends in Biochemical Sciences, 20(5), 198-202.
DOI Scopus371 WoS368 Europe PMC225
1994 Kumar, S., Matsuzaki, T., Yoshida, Y., & Noda, M. (1994). Molecular cloning and biological activity of a novel developmentally regulated gene encoding a protein with β-transducin-like structure. Journal of Biological Chemistry, 269(15), 11318-11326.
DOI Scopus27 WoS28 Europe PMC28
1994 Kumar, S., Kinoshita, M., Noda, M., Copeland, N. G., & Jenkins, N. A. (1994). Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1β-converting enzyme. Genes and Development, 8(14), 1613-1626.
DOI Scopus612 WoS614 Europe PMC464
1993 Gatei, M. H., Naif, H. M., Kumar, S., Boyle, D. B., Daniel, R. C. W., Good, M. F., & Lavin, M. F. (1993). Protection of sheep against bovine leukemia virus (BLV) infection by vaccination with recombinant vaccinia viruses expressing BLV envelope glycoproteins: Correlation of protection with CD4 T-cell response to gp51 peptide 51-70. Journal of Virology, 67(4), 1803-1810.
DOI Scopus45 WoS40 Europe PMC28
1993 Kumar, S., Iwao, M., Yamagishi, T., Noda, M., & Asashima, M. (1993). Expression of GTP-binding protein gene drg during Xenopus laevis development. International Journal of Developmental Biology, 37(4), 539-546.
Scopus23 WoS25 Europe PMC18
1993 Kumar, S., Yoshida, Y., & Noda, M. (1993). Cloning of a cDNA Which Encodes a Novel Ubiquitin-like Protein. Biochemical and Biophysical Research Communications, 195(1), 393-399.
DOI Scopus133 WoS125 Europe PMC113
1992 Sazuka, T., Tomooka, Y., Kathju, S., Ikawa, Y., Noda, M., & Kumar, S. (1992). Identification of a developmentally regulated gene in the mouse central nervous system which encodes a novel proline rich protein. Bba Gene Structure and Expression, 1132(3), 240-248.
DOI Scopus11 WoS9 Europe PMC7
1992 Kumar, S., Tomooka, Y., & Noda, M. (1992). Identification of a set of genes with developmentally down-regulated expression in the mouse brain. Biochemical and Biophysical Research Communications, 185(3), 1155-1161.
DOI Scopus487 WoS478 Europe PMC410
1992 Sazuka, T., Kinoshita, M., Tomooka, Y., Ikawa, Y., Noda, M., & Kumar, S. (1992). Expression of DRG during murine embryonic development. Biochemical and Biophysical Research Communications, 189(1), 371-377.
DOI Scopus35 WoS39 Europe PMC32
1992 Sazuka, T., Tomooka, Y., Ikawa, Y., Noda, M., & Kumar, S. (1992). DRG: A novel developmentally regulated GTP-binding protein. Biochemical and Biophysical Research Communications, 189(1), 363-370.
DOI Scopus52 WoS59 Europe PMC44
1992 Rao, D. H., Sarma, K. V., Kumar, S., Reddy, C. G., & Roa, N. P. (1992). Acceptability trials with ready to eat foods in a rural area.. Indian Pediatrics, 29(12), 1513-1518.
Scopus4 Europe PMC1
1990 Kumar, S., & Boyle, D. B. (1990). Mapping of a major early/late gene of fowlpox virus. Virus Research, 15(2), 175-185.
DOI Scopus12 WoS12 Europe PMC8
1990 Kumar, S., & Boyle, D. B. (1990). Activity of a fowlpox virus late gene promoter in vaccinia and fowlpox virus recombinants. Archives of Virology, 112(3-4), 139-148.
DOI Scopus12 WoS11 Europe PMC8
1990 Prideaux, C. T., Kumar, S., & Boyle, D. B. (1990). Comparative analysis of vaccinia virus promoter activity in fowlpox and vaccinia virus recombinants. Virus Research, 16(1), 43-57.
DOI Scopus19 WoS18 Europe PMC14
1990 Kumar, S., Andrew, M. E., Boyle, D. B., Brandon, R. B., Lavin, M. F., & Daniel, R. C. W. (1990). Expression of bovine leukaemia virus envelope gene by recombinant vaccinia viruses. Virus Research, 17(2), 131-142.
DOI Scopus14 WoS11 Europe PMC7
1990 Kumar, S., & Boyle, D. B. (1990). A poxvirus bidirectional promoter element with early/late and late functions. Virology, 179(1), 151-158.
DOI Scopus28 WoS25 Europe PMC20
1990 Coulston, J., Naif, H., Brandon, R., Kumar, S., Khan, S., Daniel, R. C. W., & Lavin, M. F. (1990). Molecular cloning and sequencing of an Australian isolate of proviral bovine leukaemia virus DNA: Comparison with other isolates. Journal of General Virology, 71(8), 1737-1746.
DOI Scopus87 Europe PMC64
1989 Kumar, S., Seymour, G. J., & Lavin, M. F. (1989). Immunoglobulin synthesis and gene rearrangement in ataxia-telangiectasia B-lymphoblastoid cell lines. International Archives of Allergy and Applied Immunology, 89(2-3), 264-268.
DOI Scopus1
1989 Baxter, G. D., Kumar, S., & Lavin, M. F. (1989). T cell receptor rearrangement and expression in ataxia-telangiectasia B lymphoblastoid cells. Immunology and Cell Biology, 67(1), 57-62.
DOI Scopus3 Europe PMC2
1989 Baxter, G. D., Collins, R. J., Harmon, B. V., Kumar, S., Prentice, R. L., Smith, P. J., & Lavin, M. F. (1989). Cell death by apoptosis in acute leukaemia. Journal of Pathology, 158(2), 123-129.
DOI Scopus71 Europe PMC42
1988 Kumar, S., Degnan, B. M., Ross, I. L., Hawkins, C. J., & Lavin, M. F. (1988). Isolation of DNA and RNA from ascidians. Marine Biology, 98(1), 95-100.
DOI Scopus11
1988 Kumar, S., Degnan, B. M., & Lavin, M. F. (1988). Cloning of a Major Repeat DNA Sequence from Pyura stolonifera. DNA, 7(6), 433-439.
DOI Scopus5 Europe PMC4
1987 Kumar, S., Baxter, G. D., Smith, P. J., Pemble, L., Collins, R. J., Prentice, R. L., & Lavin, M. F. (1987). DNA fragmentation in childhood T-cell acute lymphoblastic leukaemia.. Molecular Biology Medicine, 4(2), 111-121.
Scopus11 Europe PMC9
1987 Mohamed, R., Singh, S. P., Kumar, S., & Lavin, M. F. (1987). A defect in DNA topoisomerase II activity in ataxia-telangiectasia cells. Biochemical and Biophysical Research Communications, 149(1), 233-238.
DOI Scopus18 WoS22 Europe PMC11
1987 Lavin, M. F., Houldsworth, J., Kumar, S., Stein, J. L., & Stein, G. S. (1987). Coupling of histone mRNA levels to radioresistant DNA synthesis in ataxia-telangiectasia cells. Molecular and Cellular Biochemistry, 73(1), 45-54.
DOI Scopus7 WoS9 Europe PMC3
1986 Kumar, S., Lavin, M. F., Smith, P. J., Pemble, L., Collins, R. J., & Prentice, R. L. (1986). Rearrangements of t-cell receptor β-chain genes in human leukaemias. Molecular Immunology, 23(12), 1349-1356.
DOI Scopus2 WoS2 Europe PMC3
1986 Houldsworth, J., Kumar, S., & Lavin, M. F. (1986). Study of chromatin structure in ataxia-telangiectasia cells. Molecular Biology Reports, 11(3), 143-147.
DOI Scopus2 Europe PMC2
1985 Lavin, M., Houldsworth, J., Mohamed, R., Bates, P., & Kumar, S. (1985). Ataxia-telangiectasia: a human genetic disorder with predisposition to cancer.. Progress in Clinical and Biological Research, 172 A, 409-416.
Scopus1
1984 Kumar, S., & Nicholas, D. J. D. (1984). Na+ and K+ transport in Nitrosomonas europaea and Nitrobacter agilis. Bba Bioenergetics, 765(3), 268-274.
DOI Scopus1 WoS4
1984 Kumar, S., & Nicholas, D. J. D. (1984). Purification, properties and regulation of glutamine synthetase from Nitrobacter agilis. Journal of General Microbiology, 130(4), 959-966.
DOI Scopus4
1984 Kumar, S., & Nicholas, D. J. D. (1984). NAD+- and NADP+-dependent glutamate dehydrogenases in Nitrobacter agilis. Journal of General Microbiology, 130(4), 967-973.
DOI Scopus10
1984 KUMAR, S., & NICHOLAS, D. J. D. (1984). PURIFICATION, PROPERTIES AND REGULATION OF GLUTAMINE-SYNTHETASE FROM NITROBACTER-AGILIS. JOURNAL OF GENERAL MICROBIOLOGY, 130(APR), 959-966.
WoS9
1984 Mobashir, M., Gupta, M. C., & Kumar, S. (1984). Hepatic changes in leprosy. Clinician, 48(2), 72-79.
1983 Kumar, S., & Nicholas, D. J. D. (1983). Proton electrochemical gradients in washed cells of Nitrosomonas europaea and Nitrobacter agilis. Journal of Bacteriology, 154(1), 65-71.
DOI Scopus20 WoS24 Europe PMC13
1983 Kumar, S., Nicholas, D. J. D., & Williams, E. H. (1983). Definitive 15N NMR evidence that water serves as a source of 'O' during nitrite oxidation by Nitrobacter agilis. FEBS Letters, 152(1), 71-74.
DOI Scopus100 WoS99 Europe PMC38
1982 Hollocher, T. C., Kumar, S., & Nicholas, D. J. D. (1982). Respiration-dependent proton translocation in Nitrosomonas europaea and its apparent absence in Nitrobacter agilis during inorganic oxidations. Journal of Bacteriology, 149(3), 1013-1020.
DOI Scopus37 WoS37 Europe PMC20
1982 Kumar, S., & Nicholas, D. J. D. (1982). Assimilation of inorganic nitrogen compounds by Nitrobacter agilis. Journal of General Microbiology, 128(8), 1795-1801.
DOI Scopus5
1982 Kumar, S., & Nicholas, D. J. D. (1982). A protonmotive force-dependent adenosine-5′ triphosphate synthesis in spheroplasts of Nitrosomonas europaea. FEMS Microbiology Letters, 14(1), 21-25.
DOI Scopus9 WoS9
1982 Kumar, S., Mathur, D. R., Chaudhary, S. K., & Chawla, S. N. (1982). A comparative study of germtube formation by Candida albicans in serum and saliva of healthy individuals and diabetic patients.. Journal of Postgraduate Medicine, 28(2), 84-87.
Scopus1
1981 Bilgrami, N. L., Bilgrami, G., & Kumar, S. (1981). A serial study of ECG and electrolyte changes in albino rats after bile duct ligation.. Journal of Postgraduate Medicine, 27(1), 20-24.
Scopus1 Europe PMC1
1981 Kumar, S., & Nicholas, D. J. D. (1981). Oxygen-dependent nitrite uptake and nitrate production by cells, spheroplasts and membrane vesicles of Nitrobacter agilis. FEMS Microbiology Letters, 11(2-3), 201-206.
DOI Scopus4 WoS12
1981 Kumar, S., & Nicholas, D. (1981). Use of a thiocyanate-sensitive electrode for the determination of membrane potential in Azotobacter vinelandii. Biochemistry International, 3(6), 581-586.
Scopus3
1980 Mobashir, M., Gupta, M. C., & Kumar, S. (1980). Liver functions in leprosy. Indian Medical Gazette, 114(3), 116-120.
DOI WoS21 Europe PMC17
1980 Kumar, S., Bery, K., Goel, A., & Chawla, S. (1980). Melorheostosis. Indian Journal of Radiology, 34(4), 301-305.
1980 Tajuddin, M., Kumar, S., Tariq, M., Tyagi, S. P., & Gupta, R. (1980). Effect of radiation on myocardial metabolism and structure.. Advances in Myocardiology, 2, 233-238.
1980 Gupta, R. C., Kumar, S., & Gupta, K. K. (1980). A clinical evaluation of osteomedullography in diaphyseal fractures. Journal of Trauma Injury Infection and Critical Care, 20(6), 507-512.
DOI Scopus1 Europe PMC1
1980 Kumar, S., Joshi, K. R., Mathur, J. S., & Mathur, D. R. (1980). A study of germtube formation by Candida Albicans in biological fluids of diabetic patients.. Indian Journal of Pathology and Microbiology, 23(1), 45-49.
Scopus2 Europe PMC1
1980 Tajuddin, M., Tariq, M., Bilgrami, N. L., & Kumar, S. (1980). Biochemical and pathological changes in the heart following bile duct ligation.. Advances in Myocardiology, 2, 209-212.
Scopus19 Europe PMC11
1980 Bilgrami, N. L., Kumar, S., & Tariq, M. (1980). Myocardial catecholamines in experimental cholaemia in albino rats.. Indian Heart Journal, 32(1), 43-45.
1979 Chawla, S. N., Kumar, S., Joshi, K. R., & Mathur, D. R. (1979). Sensitivity of Pseudomonas aeruginosa to commonly used antimicrobial drugs as well as to garamycin, carbencillin & gabbromicina. Rajasthan Medical Journal, 18(4), 221-228.
Scopus2
1978 Seth, U., Bhargava, M., Vaidya, M. C., & Kumar, S. (1978). Platelet function and ultrastructure in non-thrombocytopenic bleeding of leukaemia. Indian Journal of Cancer, 15(2), 43-48.
Scopus1
1978 Kumar, S., & Chawla, S. (1978). Radiographic assessment of foetal maturity. Indian Journal of Radiology, 32(1), 19-24.
1977 Mangal, B. D., Gupta, B. K., & Kumar, S. (1977). An unusual case of scorpion bite.. Journal of the Association of Physicians of India, 25(6), 431-432.
Scopus1 Europe PMC1
1977 Mangal, B. D., Mangal, Y., Gupta, B. K., Kumar, S., & Shukla, S. K. (1977). Neuropathy in fluorosis. Journal of the Indian Medical Association, 68(9), 188-190.
Scopus1
1976 Bhargava, M., Sanyal, S. K., Thapar, M. K., Kumar, S., & Hooja, V. (1976). Impairment of platelet adhesiveness and platelet factor 3 activity in cyanotic congenital heart disease. Acta Haematologica, 55(4), 216-223.
DOI Scopus11 Europe PMC6
1976 Chawla, S. N., Abdullah, A. K., Singhal, K. C., & Kumar, S. (1976). Histamine levels in serous effusions. Indian Journal of Medical Research, 64(1), 48-56.
1976 Tajuddin, M., Kumar, S., Ahmad, K. N., Afzaal, S., & Khan, R. U. (1976). Renal histological changes in cirrhosis of liver (a preliminary study).. Journal of the Association of Physicians of India, 24(5), 283-289.
1976 Agarwal, S. C., Maheshwari, H. B., Kumar, S., & Dutta, S. (1976). Cystosarcoma phyllodes osteogenic sarcoma of the breast.. Indian Journal of Medical Sciences, 30(1), 5-6.
Scopus3 Europe PMC2
1975 Mangal, B. D., Kumar, S., Bhatia, K. B., Mitra, M. K., & Singh, R. R. (1975). Evaluation of serum and cerebrospinal fluid magnesium in cases of cerebrovascular accident--a preliminary communication.. Journal of the Association of Physicians of India, 23(5), 339-342.
Scopus4 Europe PMC1
1975 Tyagi, S. P., Gupta, M. C., Kumar, S., & Tewari, S. G. (1975). Secretion of blood group specific substances in gastric fluid. Indian Journal of Medical Research, 63(6), 873-878.
1975 Gupta, M., Bhargava, M., Kumar, S., & Mittal, M. M. (1975). Platelet function in leprosy. International Journal of Leprosy, 43(4), 327-332.
Scopus10 Europe PMC7
1974 Gupta, M. C., & Kumar, S. (1974). Chronic hypervitaminosis A in an adult.. Journal of the Association of Physicians of India, 22(11), 865-868.
Scopus1
1974 Cherian, L., Bhargava, M., Kumar, S., & Pinto De Rosario, Y. (1974). Studies on foetomaternal haemorrhage (FMH). Part I: Factors affecting foetomaternal haemorrhage. Indian Journal of Medical Research, 62(4), 546-551.
1974 Maheshwari, H. B., & Kumar, S. (1974). Effect of splenectomy on acute hepatic injury by carbon tetrachloride in albino rats. Indian Journal of Experimental Biology, 12(5), 382-384.
1974 Narang, S., Bhargava, M., & Kumar, S. (1974). Studies on foetomaternal haemorrhage (FMH). Part II. The role of placental pathology in foetomaternal haemorrhage. Indian Journal of Medical Research, 62(4), 552-556.
Scopus1 Europe PMC1
1974 Gupta, M. C., Kumar, S., Tyagi, S. P., & Srivastava, S. S. L. (1974). Stomatitis, agranulocytosis and hepatitis due to phenindione sensitivity. I.. Journal of the Indian Medical Association, 63(10), 324-327.
Scopus1
1974 Rao, P. C., Bhargava, M., & Kumar, S. (1974). Platelet function in liver disorders. Indian Journal of Medical Research, 62(9), 1303-1309.
Scopus1 Europe PMC1
1974 Gupta, M. C., Kumar, S., & Tyagi, S. P. (1974). Reappraisal of functional and structural changes in liver in leprosy.. Journal of the Association of Physicians of India, 22(1), 13-18.
Scopus1 Europe PMC1
1974 Surie, N., Bhargava, M., & Kumar, S. (1974). Platelet function in renal failure. Indian Journal of Medical Research, 62(7), 979-986.
Scopus2 Europe PMC2
1973 Agarwal, S. C., Maheshwari, H. B., & Kumar, S. (1973). Angiomatous hamartoma of the lymph node - Report of a case. Indian Journal of Pediatrics, 40(2), 61-62.
DOI Scopus1 Europe PMC1
1973 Agarwal, S. C., Maheskwari, H. B., Mittal, M. M., & Kumar, S. (1973). A histological study of liver lesions in leprosy. Indian Journal of Medical Research, 61(3), 389-395.
Scopus5 Europe PMC5
1972 Mittal, M. M., Maheshwari, H. B., & Kumar, S. (1972). Renal lesions in leprosy.. Archives of Pathology, 93(1), 8-12.
Scopus16 Europe PMC7
1971 Kumar, S., Gupta, H. B., Kunwar, K. B., & Bhatia, K. B. (1971). Clinical experience with potassium changes following blood transfusion.. Journal of the Association of Physicians of India, 19(3), 261-265.
1971 Mitra, M. K., Kumar, S., Tandon, O. P., & Kunwar, K. B. (1971). Correlation of electrocardiographic and vectorcardiographic findings in diagnosis of infero-posterior myocardial infarction.. Journal of the Association of Physicians of India, 19(2), 131-138.
1971 Kumar, S., & Dutta, N. K. (1971). An experimental study of non-agglutinable vibrios which caused gastroenteritis in clinical cases.. Indian Journal of Medical Research, 59(9), 1378-1384.
Scopus2
1971 Kunwar, K. B., Tandon, O. P., & Kumar, S. (1971). A direct method for chromosome studies of human bone marrow.. Journal of the Association of Physicians of India, 19(9), 661-665.
1971 Maheshwai, H. B., Teja, K., Rani, S., & Kumar, S. (1971). Causes of late fetal and neonatal death (an autopsy study).. Indian Pediatrics, 8(9), 417-420.
Scopus8 Europe PMC5
1971 Rani, S., Maheshwari, H. B., & Kumar, S. (1971). Chance finding of an early human embryo in endometrial curettage--a case report.. Indian Journal of Pathology Bacteriology, 14(1), 51-52.
1971 Kumar, S., & Kunwar, K. B. (1971). Chromosome abnormalities in cannabis addicts.. Journal of the Association of Physicians of India, 19(2), 193-195.
Scopus5
1970 Sharma, S. S., Kumar, S., Kunwar, K. B., Mehrotra, R. M., Chaturvedi, U. C., & Mitra, M. K. (1970). Anticardiac antibodies in ischaemic heart disease.. Journal of the Association of Physicians of India, 18(7), 595-601.
Scopus1 Europe PMC2
1970 Anand, S., Paul, S. S., Kumar, S., & Bhatia, S. L. (1970). Causes of death in low birth weight babies.. Indian Pediatrics, 7(1), 35-40.
Scopus2 Europe PMC2
1970 Gupta, M. C., Ahuja, O. P., & Kumar, S. (1970). Cavernous sinus thrombosis. Report of a case with a brief review of the literature.. Indian Journal of Medical Sciences, 24(11), 748-753.
Scopus9 Europe PMC3
1970 Kumar, S., Gupta, M. C., & Tyagi, S. P. (1970). A study of serum amylase in infective hepatitis.. Journal of the Indian Medical Association, 55(6), 194-197.
Scopus11 Europe PMC9
1970 Kumar, S., & Bhargava, M. (1970). Pre-leukaemic acute myelogenous leukaemia.. Acta Haematologica, 43(1), 21-30.
DOI Scopus11 Europe PMC9
1969 Bhargava, M., Agarwal, K. N., & Kumar, S. (1969). Sites of red cell destruction in the anaemia of experimental burns.. British Journal of Haematology, 17(2), 179-185.
DOI Scopus12 Europe PMC7
1969 Bhargava, M., & Kumar, S. (1969). The anaemia of experimental burns. I. Observations on the nature of anaemia in the immediate post-burn period.. Indian Journal of Medical Research, 57(9), 1697-1705.
Scopus2 Europe PMC2
1969 Gupta, M. C., Srivastava, U. S., & Kumar, S. (1969). Craniofacial dysostosis: Crouzon's disease. Report of two cases in a family.. Journal of the Association of Physicians of India, 17(4), 269-273.
Europe PMC1
1969 Bhargava, M., & Kumar, S. (1969). The anaemia of experimental burns. 3. Effect of heat on blood in vitro and in vivo.. Indian Journal of Medical Research, 57(10), 1860-1864.
Scopus1
1968 Teja, K., Maheshwari, H. B., & Kumar, S. (1968). Endometrioid sarcoma (stromal endometriosis). A case report.. Indian Journal of Pathology Bacteriology, 11(3), 214-218.
1968 Maheshwari, H. B., Teja, K., & Kumar, S. (1968). Lung pathology in neonatal deaths.. Indian Journal of Medical Sciences, 22(10), 696-701.
Scopus2 Europe PMC2
1967 Lal, S. K., & Kumar, S. (1967). Effect of ketosis on the blood glutathione levels in the diabetic.. Indian Journal of Medical Research, 55(5), 495-496.
Scopus8 Europe PMC1
1967 Maheshwari, H. B., Madan, P., & Kumar, S. (1967). Primary squamous cell carcinoma of corpus uteri (a case report).. Indian Journal of Pathology Bacteriology, 10(1), 95-98.
Scopus13 Europe PMC4
1967 Kunwar, K. B., & Kumar, S. (1967). Xeroderma pigmentosa with basal-cell carcinoma.. Journal of the Indian Medical Association, 48(6), 273-274.
Scopus5 Europe PMC2
1967 Kumar, S., & Rege, V. L. (1967). Trichotillomania: a case report.. Indian Journal of Medical Sciences, 21(4), 263-264.
1966 Kumar, S., Dube, B., & Mehrotra, P. N. (1966). The Macrocytosis in Cirrhosis of the Liver. Acta Haematologica, 35(1), 30-45.
DOI Scopus4 Europe PMC4
1966 Kunwar, K. B., & Kumar, S. (1966). Multiple myeloma with myeloma cells in the urine. Case report.. Indian Journal of Medical Sciences, 20(9), 641-643.
Scopus2
1966 Kunwar, K. B., Misra, S. S., Mehrotra, R. M., & Kumar, S. (1966). Turner's Syndrome. Two case reports with review of literature.. Indian Journal of Medical Sciences, 20(4), 266-275.
Europe PMC2
1966 Kunwar, K. B., Misra, S. S., Mehrotra, R. M., & Kumar, S. (1966). Nuclear sexing by buccal smear.. Journal of the Association of Physicians of India, 14(4), 247-252.
1966 Bhowal, S. C., Maheshwari, H. B., & Kumar, S. (1966). The haematologic functions of lung. II. The role of lung in the release of platelets into circulation.. Indian Journal of Pathology Bacteriology, 9(4), 303-312.
Scopus2 Europe PMC1
1966 Ghai, C. L., Chugh, K. S., Kumar, S., & Chhuttani, P. N. (1966). Electrophoretic pattern of serum proteins in secondary renal amyloidosis with nephrotic syndrome.. Journal of the Association of Physicians of India, 14(2), 141-144.
1964 MEHROTRA, A. N., MAHESHWARI, H. B., KHOSLA, S. N., & KUMAR, S. (1964). ENDOMYOCARDIAL FIBROSIS. (A REPORT OF TWO CASES IN BROTHERS).. Journal of the Association of Physicians of India, 12, 845-850.
Scopus3 Europe PMC3
1964 DATTA, A. K., & KUMAR, S. (1964). BLOOD AND CEREBROSPINAL FLUID GLUTATHIONE LEVELS IN SCHIZOPHRENIA AND THE EFFECT OF ELECTROSHOCK THERAPY ON THESE LEVELS.. Indian Journal of Medical Research, 52, 1084-1087.
1964 KUMAR, S., & MAHESHWARI, H. B. (1964). THROMBOTIC THROMBOCYTOPENIC PURPURA.. Indian Journal of Pathology Bacteriology, 10, 54-60.
1964 PAUL, C., & KUMAR, S. (1964). SERUM PROTEIN CHANGES IN NEPHROTIC SYNDROME.. Indian Journal of Medical Sciences, 18, 513-520.
1964 KUMAR, S., BHOWAL, S. C., & SARAYA, A. K. (1964). THE HAEMATOLOGIC FUNCTIONS OF LUNG. I. THE ROLE OF LUNG IN THE REMOVAL. Indian Journal of Medical Research, 52, 164-172.
1963 GHAI, C. L., & KUMAR, S. (1963). Electrophoretic patterns of serum proteins in normal Indian adults.. Indian Journal of Medical Research, 51, 344-349.
Scopus1 Europe PMC1
1963 SINGH, I. D., KUMAR, S., WIG, K. L., SINGH, H., & SACHAR, R. S. (1963). BLOOD AND CEREBROSPINAL FLUID AMMONIA AND GLUTATHIONE LEVELS IN LIVER DISEASE, AND THE EFFECT OF INTRAVENOUS GLUTAMATE ON THESE LEVELS.. Indian Journal of Medical Research, 51, 1080-1087.
Scopus1 Europe PMC1
1963 MAHESHWARI, H. B., & KUMAR, S. (1963). THROMBOTIC THROMBOCYTOPENIC PURPURA.. Journal of the Association of Physicians of India, 11, 931-936.
1962 Dube, B., & Kumar, S. (1962). Anemia in experimental cirrhosis of the rat. Acta Haematologica, 28(6), 341-351.
DOI
1962 Kumar, S., & Saraya, A. K. (1962). Experimental production of bone marrow aplasia by immunological means. Acta Haematologica, 27(5), 306-320.
DOI Scopus5 Europe PMC5
1962 DUBE, B., & KUMAR, S. (1962). Some hematologic and biochemical observations in normal albino rats.. Indian Journal of Medical Sciences, 16, 225-229.
1962 KUMAR, S., SACHDEVA, K. S., & SACHAR, R. S. (1962). Serum sodium and potassium levels in normal Indian adults.. Indian Journal of Medical Research, 50, 449-452.
1961 KUMAR, S. (1961). Experimental haemocytopoenic reactions of immunologic origin. II. Mechanism of haemolytic anaemia due to antierythrocytic serum. Indian Journal of Medical Research, 49, 1039-1050.
1960 GUPTA, S., & KUMAR, S. (1960). Studies in anaemia of infection. Part VI. Relation of plasma iron with stress and adreno-cortical function. Indian Journal of Medical Research, 48, 140-145.
Europe PMC1
1959 KUMAR, S., GUPTA, S., & MANGALIK, V. S. (1959). Studies in anaemia of infection. V. Role of reticulo-endothelial system in the regulation of plasma iron. Indian Journal of Medical Research, 47, 388-392.
Scopus2
1959 GUPTA, S., KUMAR, S., DEVI, K. P., & MANGALIK, V. S. (1959). Studies in anaemia of infection. I. Plasma iron, iron-binding capacity of the plasma and free erythrocyte protoporphyrin in normal Indian subjects.. Indian Journal of Medical Research, 47(2), 150-158.
Europe PMC2
1959 DUBE, B., KUMAR, S., & MANGALIK, V. S. (1959). Absence of abnormal haemoglobins in 235 subjects in Uttar Pradesh.. Indian Journal of Medical Research, 47(2), 148-149.
Scopus2 Europe PMC3
1959 GUPTA, S., KUMAR, S., & MANGALIK, V. S. (1959). Studies in anaemia of infection. III. Mechanism of hypoferraemia; influence of body temperature on plasma iron.. Indian Journal of Medical Research, 47(3), 266-272.
1959 KUMAR, S., GUPTA, S., & MANGALIK, V. S. (1959). Studies in anaemia of infection. IV. Mechanism of hypoferraemia: effect of infection on the absorption, excretion, and tissue distribution of iron.. Indian Journal of Medical Research, 47(3), 273-279.
Scopus1 Europe PMC1
1958 LAL, S. K., & KUMAR, S. (1958). Blood glutathione levels in the diabetic.. Indian Journal of Medical Research, 46(1), 47-51.
Scopus1
1958 KUMAR, S., KUMAR, A., AGARWAL, K. L., & MANGALIK, V. S. (1958). A study of serum proteins in kala-azar by filter paper electrophoresis.. Journal of the Indian Medical Association, 31(1), 14-17.
Europe PMC1
1958 KUMAR, S., SINGH, M. M., BHATIA, B. B., & MANGALIK, V. S. (1958). Symmetrical peripheral gangrene in acquired hemolytic anemia.. Acta Haematologica, 19(6), 369-377.
DOI Scopus3 Europe PMC2
1958 KUMAR, S. (1958). Effect of chloramphenicol on weanling rats; a study of changes in the blood and the rate of growth. Indian Journal of Medical Research, 46(2), 235-243.
1957 KUMAR, S., MANGALIK, V. S., & SEN, N. N. (1957). Role of spleen in the maintenance of circulating leukocytes. IV. Effect of splenectomy on the myeloid elements of bone-marrow in albino rats.. Indian Journal of Medical Research, 45(4), 485-492.
1957 SEN, N. N., KUMAR, S., & MANGALIK, V. S. (1957). Role of spleen in the maintenance of peripheral leucocytes. III. Effect of spleen extract on peripheral leucocyte number. Indian Journal of Medical Research, 45(1), 15-21.
Scopus1
1957 KUMAR, A., AGARWAL, K. L., KUMAR, S., & MANGALIK, V. S. (1957). Electrophoretic study of serum proteins in normal Indians.. Indian Journal of Medical Sciences, 11(6), 398-404.
Europe PMC1
1957 AGARWAL, K. L., KUMAR, A., KUMAR, S., & MANGALIK, V. S. (1957). Electrophoretic study of serum proteins in cirrhosis of the liver.. Journal of the Indian Medical Association, 29(10), 387-392.
1956 KUMAR, S., MANGALIK, V. S., & SEN, N. N. (1956). Role of spleen in the maintenance of circulating leucocytes. I. Effects of splenectomy on peripheral leucocytes.. Indian Journal of Medical Research, 44(4), 701-709.
1956 KUMAR, S., MANGALIK, V. S., & SEN, N. N. (1956). Role of spleen in the maintenance of circulating leucocytes. II. Effect of spleen transplantation on peripheral leucocyte number.. Indian Journal of Medical Research, 44(4), 711-717.
1956 KUMAR, S. (1956). Studies with anti-bone marrow sera. Indian Journal of Medical Research, 44(1), 71-80.
1954 KUMAR, S., LAL, S. K., & SINGH, G. (1954). The relation between blood glutathione+ and blood sugar in normal Punjabee adults.. Indian Journal of Medical Research, 42(1), 13-16.
1953 KUMAR, S., & LAL, S. K. (1953). Some toxic metabolic factors concerned in the development of diabetes. Indian Journal of Medical Research, 41(2), 213-234.

Year Citation
2023 Puccini, J., & Kumar, S. (2023). The Caspase family of proteases. In R. Bradshaw, G. Hart, & P. Stahl (Eds.), Source details - Title: Encyclopedia of Cell Biology (Vol. 5, 2nd ed., pp. 165-177). UK: Academic Press.
DOI Scopus2
2023 Kumar, S. (2023). Environmental contaminants and their impact on wildlife. In Toxicology and Human Health Environmental Exposures and Biomarkers (pp. 3-26). Springer Nature Singapore.
DOI Scopus7
2022 Pandey, N., Panmei, M., Goswami, J., Kundu, S., Saikia, D., Kumar, S., & Gore, K. (2022). Web of socioeconomic considerations for nature conservation in Manipur. In Case Studies of Wildlife Ecology and Conservation in India (pp. 266-275). Routledge.
DOI
2022 Kumar, S., Khan, J. A., & Khan, A. (2022). Human-tiger conflict in Corbett Tiger Reserve. In Case Studies of Wildlife Ecology and Conservation in India (pp. 113-126). Routledge.
DOI
2021 Foot, N. J., & Kumar, S. (2021). The Role of Extracellular Vesicles in Sperm Function and Male Fertility. In S. Mathivanan, P. Fonseka, C. Nedeva, & I. Atukorala (Eds.), New Frontiers: Extracellular Vesicles (Vol. 97, pp. 483-500). Switzerland: Springer International Publishing.
DOI Scopus27 Europe PMC19
2018 Henshall, T., & Kumar, S. (2018). NEDD4-2. In S. Choi (Ed.), Source details - Title: Encyclopedia of signaling molecules (2 ed., pp. 3401-3406). Cham, Switzerland: Springer, Cham.
DOI
2018 Manning, J., & Kumar, S. (2018). NEDD4. In S. Choi (Ed.), Source details - Title: Encyclopedia of Signaling Molecules (2 ed., pp. 3395-3400). Singapore: Springer.
DOI
2018 Foot, N., & Kumar, S. (2018). NDFIP1 and NDFIP2. In S. Choi (Ed.), Source details - Title: Encyclopedia of signaling molecules (2 ed., pp. 3390-3395). Singapore: Springer.
DOI
2016 Puccini, J., & Kumar, S. (2016). Caspases. In R. A. Bradshaw, & P. D. Stahl (Eds.), Encyclopedia of Cell Biology (Vol. 3, pp. 364-373). Elsevier.
DOI Scopus5
2014 Dorstyn, L., & Kumar, S. (2014). Caspase-2 protocols. In P. Bozhkov, & G. Salvasen (Eds.), Caspases, paracaspases and metacaspases: methods and protocols (Vol. 1133, pp. 71-87). Humana Press.
DOI Scopus6 Europe PMC7
2013 Dorstyn, L., & Kumar, S. (2013). Insect Caspases. In N. Rawlings, & G. Salvesen (Eds.), Handbook of Proteolytic Enzymes, Volume 2 (Vol. 2, 3 ed., pp. 2286-2295). United Kingdom: Elsevier.
DOI Scopus1
2007 Daish, T. J., & Kumar, S. (2007). The biology of caspases. In Apoptosis Cell Signaling and Human Diseases (Vol. 2, pp. 347-362). Humana Press.
DOI
2005 Dorstyn, L., & Kumar, S. (2005). Programmed cell death in drosophila melanogaster. In When Cells Die II A Comprehensive Evaluation of Apoptosis and Programmed Cell Death (pp. 79-97).
Scopus1
2004 Kumar, S. (2004). Measurement of caspase activity in cells undergoing apoptosis. In H. Brady (Ed.), Methods in Molecular Biology - Volume 282 - Apoptosis methods and protocols (Vol. 282, pp. 19-30). 999 Riverview Drive, Suite 208, Totowa, New jersey 07512, USA: Humana Press.
DOI Scopus16 Europe PMC13
2003 Kumar, S., & Cakouros, D. (2003). The role of caspases in apoptosis. In S. Grimm (Ed.), Genetics of apoptosis (pp. 31-45). 9 Newtec Place, Magdalen Road, Oxford OX4 1RE, UK: Bios Scientific Publishers Ltd.
1999 Butt, A., & Kumar, S. (1999). Caspases: the molecular effectors of apoptosis. In Signalling pathways in apoptosis, 1999 (pp. 249-264). Harwood Academic Publishers.
1998 Dorstyn, L. E., Kumar, S., & Kinoshita, M. (1998). Caspases in Cell Death. In S. Kumar (Ed.), Apoptosis: Mechanisms and Role in Disease (Vol. 24, pp. 1-24). Springer New York.
DOI Scopus12 Europe PMC4
- Kumar, S. (n.d.). Measurement of Caspase Activity in Cells Undergoing Apoptosis. In Apoptosis Methods and Protocols (pp. 019-030). Humana Press.
DOI

Year Citation
2024 Shah, M., Hung, K., Baranwal, A., Price, Z., Al-Kali, A., Toop, C., . . . Hiwase, D. (2024). The 66th ASH Annual Meeting Abstract Abstracts. In BLOOD Vol. 144 (pp. 3214). ELSEVIER.
2023 Shah, M. V., Kutyna, M., Shah, S., Tran, E. N. H., Baranwal, A., Ladon, D., . . . Hiwase, D. (2023). Comparison of World Health Organization and International Consensus Classification Guidelines for Myeloid Neoplasms Harboring TP53-Mutations Using an Independent International Cohort. In BLOOD Vol. 142 (pp. 4 pages). CA, San Diego: ELSEVIER.
DOI WoS4
2022 Kok, C. H., Tran, E. N. H., Ladon, D., Chhetri, R., Baranwal, A., Sharplin, K. M., . . . Hiwase, D. (2022). Personalized Prediction Model to Risk Stratify Patients with Therapy-Related Myeloid Neoplasms. In BLOOD Vol. 140 (pp. 6962-6963). LA, New Orleans: ELSEVIER.
DOI
2022 Kumar, S., Lim, Y., & Dorstyn, L. (2022). Tumor and aneuploidy suppression by caspase-2. In CANCER SCIENCE Vol. 113 (pp. 1 page). WILEY.
2020 Dagdeviren, S., Shah, A., Okawa, M., Melnik, V., Sarikhani, M., Foot, N., . . . Lee, R. (2020). Arrdc4 Regulates Insulin-Stimulated Glucose Metabolism. In FASEB JOURNAL Vol. 34 (pp. 2 pages). San Diego, CA: WILEY.
DOI WoS1
2016 Yip, K. H., Kolesnikoff, N., Hauschild, N., Lopez, A. F., Galli, S. J., Kumar, S., & Grimbaldeston, M. A. (2016). The Nedd4-2-Ndfip1 axis is essential to curtail mast cell-dependent IgE-mediated anaphylaxis <i>in vivo</i>. In EUROPEAN JOURNAL OF IMMUNOLOGY Vol. 46 (pp. 16-17). Melbourne, AUSTRALIA: WILEY-BLACKWELL.
2009 Dinudom, A., Lee, I. -H., Campbell, C. R., Song, S. -H., Day, M. L., Kumar, S., & Cook, D. I. (2009). EPITHELIAL Na<SUP>+</SUP> CHANNELS ARE REGULATED BY CAVEOLIN-1. In JOURNAL OF PHYSIOLOGICAL SCIENCES Vol. 59 (pp. 431). SPRINGER TOKYO.
2009 Hiwase, D. K., White, D. L., Powell, J. A., Saunders, V. A., Zrim, S., Frede, A., . . . Hughes, T. (2009). Blocking of Cytokine Survival Signals along with Intense Bcr-Abl Kinase Inhibition May Eradicate CML Progenitor Cells. In BLOOD Vol. 114 (pp. 1258-1259). New Orleans, LA: AMER SOC HEMATOLOGY.
2008 Hiwase, D. K., White, D. L., Saunders, V. A., Melo, J. V., Kumar, S., & Hughes, T. P. (2008). Short-Term Intense Bcr-Abl Kinase Inhibition Is Adequate to Trigger Cell Death in CML Cell Lines but Not in CML-CD34+Cells Unless They Are Growth Factor Deprived. In BLOOD Vol. 112 (pp. 397). San Francisco, CA: AMER SOC HEMATOLOGY.
2002 Cook, D. I., Dinudom, A., Komwatana, P., Kumar, S., & Young, J. A. (2002). Patch-clamp studies on epithelial sodium channels in salivary duct cells. In Cell Biochemistry and Biophysics Vol. 36 (pp. 105-113). COOLANGATTA, AUSTRALIA: HUMANA PRESS INC.
DOI Scopus23 WoS21 Europe PMC21

Year Citation
2023 Dawar, S., Benitez, M. C., Lim, Y., Dite, T. A., Yousef, J. M., Thio, N., . . . Clemons, N. J. (2023). Caspase-2 protects against ferroptotic cell death.
DOI
  • New mechanisms regulating the biogenesis of extracellular vesicles, ARC - Discovery Projects, 01/01/2024 - 31/12/2026

  • Regulation of autophagy dependent cell and tissue deletion, ARC - Discovery Projects, 01/01/2021 - 31/03/2024

  • Regulation of cell death, cell survival and ubiquitination in normal physiology and disease, NHMRC - Research Fellowship, 01/01/2016 - 31/12/2021

  • Deciphering the mechanisms of caspase-2-mediated suppression of aneuploidy and tumourigenesis, NHMRC - Project Grant, 01/01/2019 - 31/12/2021

  • Ubiquitination-regulated sodium homeostasis in kidney disease, NHMRC - Project Grant, 01/01/2019 - 31/12/2021

  • Using mouse models to decipher the function of caspase-2 in limiting aneuploidy tolerance and cancer, NHMRC - Project Grant, 01/01/2018 - 30/06/2021

  • Cell death by self-eating: understanding autophagy-dependent tissue removal, ARC - Discovery Projects, 13/01/2017 - 12/01/2020

  • Hormone dependent autophagy and growth signalling in developmental cell death, NHMRC - Project Grant, 01/01/2017 - 31/12/2019

  • Exploring the role of Arrcd4 in extracellular vesicle biogenesis and its implications in tissue homeostasis , NHMRC - Project Grant, 01/01/2017 - 31/12/2019

  • Nedd4-2: a new player in polycystic kidney disease, NHMRC - Project Grant, 01/01/2016 - 31/12/2018

  • Cancer Discovery Accelerator, Australian Cancer Research Foundation, 01/06/2016 - 31/07/2018

  • Deciphering the function of capcase-2 in DNA damage response and tumour suppression, NHMRC - Project Grant, 01/01/2014 - 31/12/2017

  • Post-translational control of cell fate decision, ARC - Discovery Projects, 01/01/2015 - 31/12/2017

  • Cancer Discovery Accelerator, Cancer Council SA - Beat Cancer, 08/06/2016 - 08/06/2017

Date Role Research Topic Program Degree Type Student Load Student Name
2012 - 2016 Principal Supervisor Characterisation of Pathophysiological Function of NEDD4-2 in Kidney Doctor of Philosophy Doctorate Full Time Mr Pranay Goel
2010 - 2014 Principal Supervisor Characterisation of Caspase-2 Function in the DNA Damage Response and Tumour Suppression Doctor of Philosophy Doctorate Full Time Mr Joey Puccini
2007 - 2011 Co-Supervisor Defining the role of myeloid cells in the regulation of developmental, tumour and inflammation-stimulated lymphangiogenesis Doctor of Philosophy Doctorate Full Time Ms Emma Gordon
2006 - 2009 Principal Supervisor Analysis of the Function and Regulation of the Centrosomal Protein NEDD1 During Cell Division and Development Doctor of Philosophy Doctorate Full Time Jantina Anna Manning
2006 - 2010 Co-Supervisor Evaluation of Anti-proliferative and Pro-apoptotic Effects of Tyrosine Kinase Inhibitors on CML-CD34+ Cells Doctor of Philosophy Doctorate Full Time APrf Devendra Hiwase
2001 - 2005 Principal Supervisor Regulation of sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2 Doctor of Philosophy Doctorate Full Time Mr Andrew Fotia
2001 - 2005 Principal Supervisor An analysis of DRONC function and its regulation of expression during Drosophila development Doctor of Philosophy Doctorate Full Time Dr Tasman Daish
2000 - 2004 Principal Supervisor Characterisation of a Novel Caspase STRICA and the Bcl-2 Homologues BUFFY and DEBCL in Drosophila melanogaster Doctor of Philosophy Doctorate Full Time Miss Joanna Doumanis

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