Shankar Devkota

Research Interests

Biochemistry & Molecular Biology Proteins and Peptides Structural biology (incl. macromolecular modelling) Drug discovery

Dr Shankar Devkota

Postdoctoral Research Fellow (A) (with PhD)

School of Chemical Engineering

College of Engineering and Information Technology

Eligible to supervise Masters and PhD (as Co-Supervisor) - email supervisor to discuss availability.

Available For Media Comment.

I am dedicated to the exploration and characterisation of novel proteins with broad applications in science and industry. My research focuses on uncovering proteins with potential to drive advancements in healthcare, sustainable technologies and other critical fields. I am particularly interested in developing innovative and environmentally friendly approaches, leveraging protein-based tools to address global challenges in medicine, resource recovery and beyond.

 

Date Position Institution name
2023 - 2026 Research Fellow University of Adelaide
2020 - 2022 Teaching Associate Monash University

Date Institution name Country Title
2019 - 2023 Monash University Australia PhD
2015 - 2017 Yeungnam University South Korea Masters in Pharmacy

Year Citation
2026 Kunwar, S., Devkota, S. R., Ang, C., Aryal, P., Gai, W., Pokhrel, R., . . . Bhusal, R. P. (2026). Discovery of an evolutionarily distinct evasin with dual CC and CXC chemokine inhibitory activity. Structure, 34(5), 732-746.
DOI Europe PMC1
2026 Li, Y., Hui, Y., Wang, J., Guo, Z., Ye, Z., Orchard, M., . . . Zhao, C. -X. (2026). Minimal Peptide Surfactants for Long-Lasting Nanoemulsions via Noncovalent Interfacial Interactions. ACS applied materials & interfaces, 18(17), 25590-25602.
DOI
2026 Devkota, S. R., Aryal, P., Bell, M., Kunwar, S., Stone, M. J., & Bhusal, R. P. (2026). Principles for the design of multispecific proteins. Trends in Biochemical Sciences, 51(6), 538-541.
DOI
2025 Yang, G., Liu, Y., Devkota, S. R., Hui, Y., Zhao, R., Li, Y., . . . Zhao, C. (2025). A Sustainable Biotechnology Approach for Mineral Separation. Advanced Functional Materials, 35(50), e04992-1-e04992-16.
DOI Scopus1 WoS1
2024 Jha, S. K., De Rubis, G., Devkota, S. R., Zhang, Y., Adhikari, R., Jha, L. A., . . . Paudel, K. R. (2024). Cellular Senescence in Lung Cancer: Molecular Mechanisms and Therapeutic Interventions.. Ageing Research Reviews, 97, 102315-1-102315-21.
DOI Scopus116 WoS116 Europe PMC83
2024 Devkota, S. R., Aryal, P., Wilce, M. C. J., Payne, R. J., Stone, M. J., & Bhusal, R. P. (2024). Structural basis of chemokine recognition by the class A3 tick evasin EVA-ACA1001. Protein Science, 33(6), e4999-1-e4999-11.
DOI Scopus5 WoS5 Europe PMC5
2024 Hussain, K., Lim, H. D., Devkota, S. R., Kemp-Harper, B. K., Lane, J. R., Canals, M., . . . Stone, M. J. (2024). The chemokine receptor CCR8 is not a high-affinity receptor for the human chemokine CCL18. PLoS One, 19(9), e0305312-1-e0305312-20.
DOI WoS2 Europe PMC1
2023 Li, Y., Yang, G., Weng, Y., Xu, L., Hou, F., Devkota, S., & Zhao, C. -X. (2023). Exploring biosurfactants as a sustainable alternative to chemical surfactants. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 677(Part A), 132291-1-132291-11.
DOI Scopus23 WoS20
2023 Devkota, S. R., Aryal, P., Pokhrel, R., Jiao, W., Perry, A., Panjikar, S., . . . Stone, M. J. (2023). Engineering broad-spectrum inhibitors of inflammatory chemokines from subclass A3 tick evasins. Nature Communications, 14(1), 4204-1-4204-12.
DOI Scopus8 WoS8 Europe PMC4
2022 Aryal, P., Devkota, S. R., Jeevarajah, D., Law, R., Payne, R. J., Bhusal, R. P., & Stone, M. J. (2022). Swapping N-terminal regions among tick evasins reveals cooperative interactions influencing chemokine binding and selectivity. Journal of Biological Chemistry, 298(10), 102382-1-102382-11.
DOI Scopus9 WoS9 Europe PMC7
2022 Bhusal, R. P., Aryal, P., Devkota, S. R., Pokhrel, R., Gunzburg, M. J., Foster, S. R., . . . Stone, M. J. (2022). Structure-guided engineering of tick evasins for targeting chemokines in inflammatory diseases. Proceedings of the National Academy of Sciences of USA, 119(9), e2122105119-1-e2122105119-7.
DOI WoS15 Europe PMC10
2021 Klionsky, D. J., Abdel Aziz, A. K., Abdelfatah, S., Abdellatif, M., Kumar, S., & Tong, C. K. (2021). Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy, 17(1), 1-382.
DOI Scopus2301 WoS2015 Europe PMC2231
2021 Sai, K., Chhetri, S. B. B., Devkota, S. R., & Khatri, D. (2021). Evaluation of the Hypoglycemic Potential of Leaves Extract of Spondias pinnata (L.f.) Kurz. From Nepal. Scientific World Journal, 2021, 3230351-1-3230351-6.
DOI Scopus5 Europe PMC1
2019 Kwon, E., Devkota, S. R., Pathak, D., Dahal, P., & Kim, D. Y. (2019). Structural analysis of the recognition of the -35 promoter element by SigW from Bacillus subtilis. PLoS One, 14(8), e0221666-1-e0221666-13.
DOI Scopus6 WoS5 Europe PMC5
2017 Devkota, S. R., Kwon, E., Ha, S. C., Chang, H. W., & Kim, D. Y. (2017). Structural insights into the regulation of Bacillus subtilis SigW activity by anti-sigma RsiW. Plos One, 12(3), 15 pages.
DOI Scopus27 WoS24 Europe PMC19

Year Citation
2026 So, S. S., Lona, A., Pokhrel, R., Morgan, A. L., Saltikova, M., Nguyen, T., . . . Stone, M. J. (2026). Monocyte Migration Emerges from a Divergent Chemokine Signaling Network..
DOI
2023 Devkota, S., Aryal, P., Jiao, W., Perry, A., Panjikar, S., Payne, R., . . . Stone, M. (2023). Engineering Broad-spectrum Inhibitors of Inflammatory Chemokines from a New Family of Tick Evasins.
DOI
2026 AEA Ignite                                    $422,174 Revolutionising Mineral Processing: Innovative Sustainable Biotechnology Approach for Mineral Separation
2024 University of Adelaide    $13,725 Research Small Equipment Support Scheme 

 

Date Role Research Topic Program Degree Type Student Load Student Name
2026 Co-Supervisor Novel biomolecules for the separation of critical minerals Doctor of Philosophy Doctorate Full Time Mr Sohei Iwama
2025 Co-Supervisor A Sustainable Approach for Mineral Processing and Recycling Doctor of Philosophy Doctorate Full Time Mr Ruilin Zhao

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