Shadrack Mutuku

Mr Shadrack Mutuku

PhD Candidate

Adelaide Medical School

Faculty of Health and Medical Sciences

Shadrack Mutuku is a PhD student at the Adelaide Medical School and a recipient of the University of Adelaide International Wildcard Scholarship. He holds a MSc. in Drug Discovery and Pharmaceutical Sciences from the University of Nottingham, UK and a BSc. in Biochemistry and Molecular Biology from the Jomo Kenyatta University of Agriculture and Technology, Kenya. His Masters project involved using an immobilised artificial membrane as a lipid bilayer model to study it's effects on drug-receptor kinetics. In 2016, he has joined the Prostate Cancer Research Group at SAHMRI to exploit the application of mass spectrometry imaging in characterising lipid changes in prostate tissue during anti-cancer therapy.

I am exploiting the application of mass spectrometry imaging in characterising lipid changes in prostate tissue during anti-cancer therapy.

  • Journals
    Year Citation
    2020 Mutuku, S. (2020). Lipidomic profiling of clinical prostate cancer reveals targetable alterations in membrane lipid composition. bioRxiv.
    2019 Mutuku, S. M., Trim, P. J., Prabhala, B. K., Irani, S., Bremert, K. L., Logan, J. M., . . . Butler, L. M. (2019). Evaluation of small molecule drug uptake in patient-derived prostate cancer explants by mass spectrometry. Scientific Reports, 9(1), 15008.
    DOI Scopus3 WoS4
    2018 Geberselassie, S., Abebe, M., Melsew, A., Mutuku, S., & Wassie, M. M. (2018). Prevalence of stunting and its associated factors among children 6-59 months of age in Libo-Kemekem district, Northwest Ethiopia; A community based cross sectional study. PLoS ONE, 13(5), 1-11.
    DOI Scopus17 WoS14 Europe PMC10

  • Conference Items
    Year Citation
    2019 Mutuku, S. M. (2019). MALDI Imaging to Characterise the Lipid Signature of Clinical Prostate Tumours. Poster session presented at the meeting of American Society for Mass Spectrometry. Atlanta.
    2018 Mutuku, S. M. (2018). Evaluation of Small Molecule Drug Uptake in Ex Vivo Cultured Clinical Prostate Tumours by Mass Spectrometry. Poster session presented at the meeting of 12th Florey Postgraduate Research Conference.
    2018 Mutuku, S. M., Centenera, M. M., Trim, P. J., Snel, M. F., & Butler, L. M. (2018). Evaluation of small molecule drug uptake in ex vivo cultured clinical prostate tumours by mass spectrometry. Poster session presented at the meeting of BJU INTERNATIONAL. Brisbane, AUSTRALIA: WILEY.
    2017 Mutuku, S. M., Prabhala Bala., Centenera, M., Trim, P., Snel, M., & Butler, L. (2017). Quantification of Enzalutamide in Cultured Prostate Tissue Using LC-MS/MS. Poster session presented at the meeting of 26th Australian and New Zealand Society for Mass Spectrometry. Flinders University.
    2017 Mutuku, S. M., Centenera, M., Trim, P., Gustafsson, O. J., Snel, M., & Butler, L. (2017). A Mass Spectrometry Approach to Characterise Lipid Composition in Prostate Tumuors. Poster session presented at the meeting of 11th Florey Postgraduate Research Conference. Adelaide.

Australian and New Zealand Society for Mass Spectrometry (ANZSMS) Travel Grant

  • Other Supervision Activities
    Date Role Research Topic Location Program Supervision Type Student Load Student Name
    2018 - 2019 Other Demonstrator (Medical Sciences & Neuroscinces) University of Adelaide — Other Part Time 3rd Year Research Placement

  • Mentoring
    Date Topic Location Name
    2017 - 2018 Mass Spectrometry Imaging of Lipids in Prostate Tissue KU Leuven Daan Van Den Bosch
  • Position: PhD Candidate
  • Phone: 81284374
  • Email: shadrack.mutuku@adelaide.edu.au
  • Campus: North Terrace
  • Building: SAHMRI, floor 5
  • Org Unit: Adelaide Medical School
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