Scott Smid

Dr Scott Smid

Senior Lecturer

Adelaide Medical School

Faculty of Health and Medical Sciences

Eligible to supervise Masters and PhD - email supervisor to discuss availability.


Dr Scott Smid is a pharmacologist specializing in drug discovery and development research both in industry and academia. He maintains a strong research interest in experimental therapeutics applied towards novel treatments for gastrointestinal and neurodegenerative diseases. This includes investigating the biological actions of phytocannabinoids, synthetic cannabinoids and endocannabinoids in areas as diverse as gut function, inflammation and neurodegeneration. Current interests include novel ligand development for binding and inhibiting pathological aggregating proteins such as beta-amyloid and alpha-synuclein, which are associated with Alzheimer's and Parkinson's disease.

Dr Scott Smid is a pharmacologist specializing in drug discovery and development research both in industry and academia. He maintains a strong research interest in experimental therapeutics applied towards novel treatments for gastrointestinal and neurodegenerative diseases. This includes investigating the biological actions of phytocannabinoids, synthetic cannabinoids and endocannabinoids in areas as diverse as gut function, inflammation and neurodegeneration.

Current projects for Honours or PhD candidates include:

1. Identifying novel cannabis phytochemicals with neuroprotective properties. This includes using neural stem cells and other neuronal cell populations to model neurotoxicity to dementia associated misfolding proteins such as amyloid beta and alpha-synuclein, related to Alzheimer's and Parkinson's disease.

2. Identifying novel cannabis phytochemicals with gastroprotective properties. This projects looks at identifying novel cannabis phytochemicals with mucoprotective properties in the gut lining, related to inflammatory and other injurious conditions such as Crohn's disease and chemotherapy.

3. Understanding cannabis-herb and cannabis-drug interactions. This is a molecular toxicology project aimed at understanding how cannabis and its components can influence metabolic pathways that may affect conventional medications or complementary medicines, causing potential toxicity.

    Expand
  • Appointments

    Date Position Institution name
    2015 Visiting Fellow University of Western Australia, Perth
    2012 Deputy Head University of Adelaide, Adelaide
    2010 - 2014 Postgraduate Coordinator University of Adelaide, Adelaide
    2006 Senior Lecturer University of Adelaide, Adelaide
  • Awards and Achievements

    Date Type Title Institution Name Country Amount
    2012 Award Faculty International Conference Award (FICA)
  • Education

    Date Institution name Country Title
    1991 - 1994 University of Adelaide, Adelaide Australia Doctor of Philosophy
    1990 University of Adelaide, Adelaide Australia Honours Degree of Bachelor of Science (Class 1 Honours)
    1979 - 1989 University of Adelaide, Adelaide Australia Bachelor of Science
  • Research Interests

Grants and Funding
Research Support and Scholarship
2018 Principal Investigator. Faculty Research Infrastructure Award. The University of Adelaide. AUD $17,000
2017-18 Principal Investigator. Faculty Research Development Award (with Prof Kato, Nagoya University and Dr Ian Musgrave). Novel neuroprotective agents targeting beta amyloid. The University of Adelaide. AUD $15,500
2013-15 Co-Investigator (with Ian Musgrave, Louise O’Keefe and Tara Pukala). 'Structure function relationships of anti-amyloid drugs: verification in an in-vivo model.' lnterdisciplinary Research Fund Grant, The University of Adelaide. AUD $21,000
2011-13 Principal Investigator. (Associate Investigator: Dr Rachel Gibson). Validation of an ex vivo human colonic mucosal explant colitis model. MAWA Trust Research Grant. AUD $28,122
2013 Principal Investigator (with Drs A. Humpage and L. Fabbro). Characterisation of cyanobacterial Limnothrix muco- and neurotoxicity. School of Medical Sciences SRE project funding. AUD $3000
2010-12 Principal Investigator Broad Medical Research Program, United States (IBD-0268R). Functional Expression of the Endocannabinoid System in Inflammatory Bowel Disease. USD $130,000
Development Initiatives and Funding: Teaching and Internationalisation
2015 Priority Partner Funding Grant, Nagoya University. Linkage facilitation. $3000
2014-15 BEACON Set-Up Grants for New Study Tours. Establishing a program of study abroad electives for Bachelor of Health Sciences students to Sweden. $5,000
2013 International Office, University of Gothenburg. G. Tobin, M Winder, P. Aronsson and S Smid. "International mobility: Extended bilateral cooperation with the University of Adelaide". 30,000 SEK
2011-12

Seminar: Blended learning approaches to practical teaching in pharmacology: the best of both worlds? 6th ERGA Conference, University of Adelaide, Sep. 28-30.

Seminar: Development of discipline specific teaching tools based on LabTutor to improve practicum delivery. ASCEPT Education Workshop, Perth, Dec.4. 2011.

Seminar: e-learning in an online environment in pharmacokinetics. e-learning forum, School of Medical Sciences, Sep. 3, 2012.

 
Teaching and Course Coordination
2006-present The University of Adelaide: Course Coordinator - PHARM 3102 Drug Discovery & Development (2017-present); Research Placements Coordinator (HLTH SC 3007/8 A&B); Pharmacology 3010/3011 (Level 3 B.Sc., B.Hlth.Sci from 2006-17). Courses taught: Pharmacology 2100/2200 (Level 2 B.Hlth.Sci, B. Pharm. Eng.). Pharmacology for Nursing (Level 1&2, Bachelor of Nursing). PHARM 3101, 3102, HLTH SC 2103, 2104, 3100. Higher Degree by Research: Discipline Coordinator (2007-2014); School of Medical Sciences HDR Committee Chair 2015.
    Expand
  • Current Higher Degree by Research Supervision (University of Adelaide)

    Date Role Research Topic Program Degree Type Student Load Student Name
    2019 Principal Supervisor Neuroprotective Bioactivity of Marine and Plant Based Polyphenols Doctor of Philosophy Doctorate Full Time Mr Srijan Shrestha
    2017 Principal Supervisor Enteric Neuronal Formation and Expression of Amyloidogenic Proteins Doctor of Philosophy Doctorate Full Time Mr Dylan Thomas Marsh
    2016 Co-Supervisor Characterising the immune profile in Inflammatory Bond Disease using novel in-vivo imaging technologies. Doctor of Philosophy Doctorate Full Time Miss Nicole Dmochowska
  • Past Higher Degree by Research Supervision (University of Adelaide)

    Date Role Research Topic Program Degree Type Student Load Student Name
    2015 - 2018 Principal Supervisor Small molecular inhibitors of Amyloid beta and alpha Synuclein amyloidogenic aggregation, toxicity and in silico design of amyloid-binding ligands Doctor of Philosophy Doctorate Full Time Mrs Sukanya Das
    2010 - 2014 Principal Supervisor The Effect of Cannabinoids on Cytokine Evoked Human Colonic Mucosal Damage and Caco-2 Epithelial Permeability Doctor of Philosophy Doctorate Full Time Mr Benjamin Harvey
  • Position: Senior Lecturer
  • Phone: 83135287
  • Email: scott.smid@adelaide.edu.au
  • Fax: 8224 0685
  • Campus: North Terrace
  • Building: Helen Mayo North, floor 5
  • Room: 5 31
  • Org Unit: Medical Sciences

Connect With Me
External Profiles