Associate Professor Sarah Vreugde
Grant-Funded Researcher (E)
Adelaide Medical School
Faculty of Health and Medical Sciences
Professor Sarah Vreugde
Director of Research: ENT Surgery
The Department of Otolaryngology, Head and Neck Surgery at The Queen Elizabeth Hospital is committed to excellence in translational research and education. Research in our department is focused mainly on understanding the pathogenesis of chronic rhinosinusitis (CRS), using a multidisciplinary approach, aimed at identifying new diagnostic/prognostic markers and treatment strategies to the benefit of our patients. Research projects cover all aspects of rhinological research from pathophysiological aspects of CRS to the identification and validation of new treatment strategies in vitro and in vivo, bringing research from bench to bedside.
Our Department of ENT has an excellent track record of Honours and Higher degree supervision with a 100% completion rate. Professor PJ Wormald was recognized for “Excellence in Research Supervision” by The University of Adelaide in 2013. We are always interested in students that have exceptional motivation and are passionate about research and in return we provide them with full support in terms of research supervision direction.
Projects in my laboratory are focused on diseases of the ear, nose and throat. In particular, my research is focused on pathophysiological aspects of chronic rhinosinusitis, aimed at the identification and validation of new diagnostic and treatment strategies in vitro and in vivo. Projects range from defining molecular mechanisms and microbial determinants of chronic inflammation to the validation of anti-bacterial and wound-healing compounds in vitro and in vivo.
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Appointments
Date Position Institution name 2024 - ongoing Professor University of Adelaide 2017 - 2023 Associate Professor The University of Adelaide 2013 - 2016 Senior Scientist The University of Adelaide 2008 - 2011 Patent Examiner European Patent Office 2003 - 2006 Post-doctoral research scientist Istituto Scientifico San Raffaele (IRCCS), Milan 2003 - 2006 Consultant San Raffaele Hospital, Milan -
Language Competencies
Language Competency Dutch; Flemish Can read, write, speak, understand spoken and peer review English Can read, write, speak, understand spoken and peer review French Can read, write, speak, understand spoken and peer review German Can read, speak and understand spoken Hebrew Can speak and understand spoken Italian Can read, write, speak, understand spoken and peer review -
Education
Date Institution name Country Title 1998 - 2002 Tel Aviv University Israel PhD 1994 - 2000 Free University Brussels Belgium ENT Specialisation 1994 Free University Brussels Belgium MD -
Research Interests
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Journals
Year Citation 2025 Pourmehran, O., Psaltis, A. J., Vreugde, S., Zarei, K., Shang, Y., Inthavong, K., & Wormald, P. -J. (2025). Evaluating Nebulisation and Nasal Irrigation Efficiency in Post-Operative Chronic Rhinosinusitis Patients Through Computational Fluid Dynamics Simulation. Computer Methods and Programs in Biomedicine, 264, 108697-1-108697-18.
Scopus1 Europe PMC12025 Feizi, S., Cooksley, C. M., Reyne, N., Boog, B., Finnie, J., Shaghayegh, G., . . . Vreugde, S. (2025). An immunocompetent rat model of Mycobacterium abscessus multinodular granulomatous lung infection. Tuberculosis, 152, 102629-1-102629-8.
Scopus12025 Hao, N., Vreugde, S., Fitridge, R., & Shearwin, K. E. (2025). Complete genome sequence of Anaerococcus sp. strain AH8042_DFU013_CI05 isolated from a diabetes-related foot ulcer.. Microbiology Resource Announcements, 14(4), e0132624-1-e0132624-4.
2025 Fong, S. A., Bouras, G., Houtak, G., Nepal, R., Feizi, S., Morales, S., . . . Vreugde, S. (2025). Genomic variation in Pseudomonas aeruginosa clinical respiratory isolates with de novo resistance to a bacteriophage cocktail. Microbiology Spectrum, 13(5), e02149-24-1-e02149-24-22.
2025 Paramasivan, S., Bassiouni, A., Bokulich, N. A., Ramezanpour, M., Cooksley, C., Caporasso, J. G., . . . Vreugde, S. (2025). Tertiary Lymphoid Organs Are Associated With Bacterial Dysbiosis in Chronic Rhinosinusitis. International Forum of Allergy and Rhinology, e23608-1-e23608-4.
2025 Burdon, I., Bouras, G., Fenix, K., Yeo, K., Connell, J., Cooksley, C., . . . Psaltis, A. J. (2025). Metagenomics or Metataxonomics: Best Practice Methods to Uncover the Sinus Microbiome. International Forum of Allergy and Rhinology, 4 pages.
2024 Kennewell, T. L., Haidari, H., Mashtoub, S., Howarth, G. S., Wormald, P. J., Cowin, A. J., . . . Kopecki, Z. (2024). Deferiprone and Gallium-Protoporphyrin Chitogel as an antimicrobial treatment: Preclinical studies demonstrating antimicrobial activity for S. aureus infected cutaneous wounds. International Journal of Biological Macromolecules, 276(Pt 1), 133874.
Scopus3 Europe PMC22024 Connell, J. T., Bouras, G., Yeo, K., Fenix, K., Cooksley, C., Bassiouni, A., . . . Psaltis, A. J. (2024). Characterising the allergic fungal rhinosinusitis microenvironment using full-length 16S rRNA gene amplicon sequencing and fungal ITS sequencing.. Allergy, 79(11), 3082-3094.
Scopus4 Europe PMC12024 Candy, N. G., Ramezanpour, M., Bouras, G., Chegeni, N., Chataway, T., Ormsby, R. J., . . . Psaltis, A. J. (2024). Differential proteomic expression in non-functional pituitary neuroendocrine tumours and pituitary glands. Rhinology, 62(6), 750-758.
2024 Lee, J., Carda-Diéguez, M., Vreugde, S., Cooksley, C., Mashayamombe, M., Dawson, J., . . . Kidd, S. P. (2024). Characterising the role of enolase in a stable Small Colony Variant of Staphylococcus aureus isolated from a diabetic foot infection patient with osteomyelitis.. Microbial Pathogenesis, 196, 106918.
Scopus12024 Yeo, K., Wu, F., Li, R., Smith, E., Wormald, P. -J., Valentine, R., . . . Fenix, K. (2024). Is Short-Read 16S rRNA Sequencing of Oral Microbiome Sampling a Suitable Diagnostic Tool for Head and Neck Cancer?. Pathogens, 13(10), 826-1-826-20.
Scopus3 Europe PMC32024 Meymivand, A., Shirani, M., Yamini, Y., Shahhosseini, S., Kashani, M. N., Pourmehran, O., & Vreugde, S. (2024). Polymeric membrane supports in electromembrane extraction: An overview of various options, methodologies, and modifications. TrAC - Trends in Analytical Chemistry, 181(Part B), 117994-1-117994-17.
Scopus12024 Ramezanpour, M., Feizi, S., Arachchige, H. D. P., Bouras, G., Cooksley, C., Shaghayegh, G., . . . Vreugde, S. (2024). Evaluation of mucosal barrier disruption due to Staphylococcus lugdunensis and Staphylococcus epidermidis exoproteins in patients with chronic rhinosinusitis. International Forum of Allergy and Rhinology, 15(3), 267-277.
2024 Feizi, S., Awad, M., Ramezanpour, M., Cooksley, C., Murphy, W., Prestidge, C. A., . . . Vreugde, S. (2024). Promoting the Efficacy of Deferiprone-Gallium-Protoporphyrin (IX) against <i>Mycobacterium abscessus</i> Intracellular Infection with Lipid Liquid Crystalline Nanoparticles.. ACS applied materials & interfaces, 16(51), 70274-70283.
Scopus1 Europe PMC12024 Connell, J. T., Yeo, K., Bouras, G., Bassiouni, A., Fenix, K., Cooksley, C., . . . Psaltis, A. J. (2024). Enhanced phylogenetic insights into the microbiome of chronic rhinosinusitis through the novel application of long read 16S rRNA gene amplicon sequencing.. Rhinology, 0(0), 0.
Scopus3 Europe PMC22024 Yeo, K., Li, R., Wu, F., Bouras, G., Mai, L. T. H., Smith, E., . . . Fenix, K. (2024). Identification of consensus head and neck cancer-associated microbiota signatures: a systematic review and meta-analysis of 16S rRNA and The Cancer Microbiome Atlas datasets. Journal of Medical Microbiology, 73(2), 001799-1-001799-18.
Scopus6 Europe PMC52024 Kennewell, T. L., Haidari, H., Mashtoub, S., Howarth, G. S., Bennett, C., Cooksley, C. M., . . . Kopecki, Z. (2024). Deferiprone-Gallium-Protoporphyrin Chitogel Decreases Pseudomonas aeruginosa Biofilm Infection without Impairing Wound Healing. Materials, 17(4), 19 pages.
Scopus2 Europe PMC22024 Murphy, W., Liu, S., Javadiyan, S., Vyskocil, E., Feizi, S., Callejas, C., . . . Psaltis, A. J. (2024). An In Vitro Study Evaluating the Safety of Mesalazine on Human Nasoepithelial Cells. International Journal of Molecular Sciences, 25(5), 2796.
Scopus2 Europe PMC12024 Murphy, W., Liu, S., Hon, K., Finnie, J., Bouras, G. S., Feizi, S., . . . Psaltis, A. J. (2024). A Novel Model of Staphylococcus aureus-Induced Lymphoplasmacytic Rhinosinusitis in Rats. International Journal of Molecular Sciences, 25(6), 3336-1-3336-13.
Scopus1 Europe PMC12024 Megow, A., Bouras, G., Ooi, E. H., Vreugde, S., Psaltis, A., & Wormald, P. J. (2024). Double blind randomized controlled trial measuring the efficacy of nebulized steroid at half dose in comparison to high volume squeeze bottle steroid irrigation in management of patients with chronic rhinosinusitis. International Forum of Allergy and Rhinology, 14(8), 1375-1377.
Scopus12024 Houtak, G., Nepal, R., Bouras, G., Shaghayegh, G., Bennett, C., Finnie, J., . . . Vreugde, S. (2024). Staphylococcus aureus Biofilm-Secreted Factors Cause Mucosal Damage, Mast Cell Infiltration, and Goblet Cell Hyperplasia in a Rat Rhinosinusitis Model. International Journal of Molecular Sciences, 25(6), 3402-1-3402-22.
Scopus4 Europe PMC42024 Dhungana, G., Nepal, R., Houtak, G., Bouras, G., Vreugde, S., & Malla, R. (2024). Preclinical characterization and in silico safety assessment of three virulent bacteriophages targeting carbapenem-resistant uropathogenic Escherichia coli. International Microbiology, 27(6), 1747-1763.
Scopus2 Europe PMC12024 Megow, A., Bouras, G., Alsuliman, Y., Cooksley, C., Vyskocil, E., Murphy, W., . . . Wormald, P. -J. (2024). Chitogel with deferiprone following endoscopic sinus surgery: improved wound healing and microbiome. Frontiers in Surgery, 11, 1338209-1-1338209-13.
2024 Shaghayegh, G., Cooksley, C., Bouras, G., Panchatcharam, B. S., Feizi, S., Javadian, S., . . . Vreugde, S. (2024). S. aureus biofilm properties correlate with immune B cell subset frequencies and severity of chronic rhinosinusitis. Clinical Immunology, 263, 110221-1-110221-16.
Scopus3 Europe PMC22024 Yeo, K., Connell, J., Bouras, G., Smith, E., Murphy, W., Hodge, J. -C., . . . Fenix, K. A. (2024). A comparison between full-length 16S rRNA Oxford nanopore sequencing and Illumina V3-V4 16S rRNA sequencing in head and neck cancer tissues. Arch Microbiol, 206(6), 248-1-248-14.
Scopus9 Europe PMC62024 Le, H. -P., Hassan, K., Ramezanpour, M., Campbell, J. A., Tung, T. T., Vreugde, S., & Losic, D. (2024). Development of novel iron(III) crosslinked bioinks comprising carboxymethyl cellulose, xanthan gum, and hyaluronic acid for soft tissue engineering applications. Journal of Materials Chemistry B, 12(27), 6627-6642.
Scopus8 Europe PMC32024 Tuli, J. F., Ramezanpour, M., Cooksley, C., Bouras, G. S., Ogi, K., Feizi, S., . . . Vreugde, S. (2024). Increased antibiotic resistance of Pseudomonas aeruginosa isolates from chronic rhinosinusitis patients grown in anaerobic conditions. Laryngoscope Investigative Otolaryngology, 9(3), e1244-1-e1244-9.
Scopus1 Europe PMC22024 Bouras, G., Houtak, G., Wick, R. R., Mallawaarachchi, V., Roach, M. J., Papudeshi, B., . . . Vreugde, S. (2024). Hybracter: enabling scalable, automated, complete and accurate bacterial genome assemblies. Microbial Genomics, 10(5), 001244-1-001244-15.
Scopus17 Europe PMC232024 Bouras, G., Judd, L. M., Edwards, R. A., Vreugde, S., Stinear, T. P., & Wick, R. R. (2024). How low can you go? Short-read polishing of Oxford Nanopore bacterial genome assemblies. Microbial Genomics, 10(6), 001254-1-001254-9.
Scopus23 Europe PMC312023 Bouras, G., Nepal, R., Houtak, G., Psaltis, A. J., Wormald, P. -J., & Vreugde, S. (2023). Pharokka: a fast scalable bacteriophage annotation tool. Bioinformatics, 39(1), 1-4.
Scopus190 WoS8 Europe PMC1942023 Shaghayegh, G., Cooksley, C., Bouras, G. S., Panchatcharam, B. S., Idrizi, R., Jana, M., . . . Vreugde, S. (2023). Chronic rhinosinusitis patients display an aberrant immune cell localization with enhanced S aureus biofilm metabolic activity and biomass. Journal of Allergy and Clinical Immunology, 151(3), 723-736.e16.
Scopus82023 Farnoud, A., Tofighian, H., Baumann, I., Ahookhosh, K., Pourmehran, O., Cui, X., . . . Schmid, O. (2023). Numerical and Machine Learning Analysis of the Parameters Affecting the Regionally Delivered Nasal Dose of Nano- and Micro-Sized Aerosolized Drugs. Pharmaceuticals, 16(1), 81-1-81-14.
Scopus8 Europe PMC32023 Feizi, S., Cooksley, C. M., Ramezanpour, M., Nepal, R., Psaltis, A. J., Wormald, P. -J., & Vreugde, S. (2023). Colloidal silver against macrophage infections and biofilms of atypical mycobacteria.. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 36(4), 913-925.
Scopus10 WoS1 Europe PMC22023 Dhakal, B., Li, C. M. Y., Ramezanpour, M., Houtak, G., Li, R., Bouras, G., . . . Fenix, K. (2023). Proteomic characterisation of perhexiline treatment on THP-1 M1 macrophage differentiation. Frontiers in Immunology, 14, 13 pages.
Scopus3 WoS1 Europe PMC32023 Shaghayegh, G., Cooksley, C., Bouras, G., Nepal, R., Houtak, G., Panchatcharam, B. S., . . . Vreugde, S. (2023). Staphylococcus aureus biofilm properties and chronic rhinosinusitis severity scores correlate positively with total CD4+ T-cell frequencies and inversely with its Th1, Th17 and regulatory cell frequencies. Immunology, 170(1), 120-133.
Scopus6 Europe PMC42023 Lee, J., Mashayamombe, M., Walsh, T. P., Kuang, B. K. P., Pena, G. N., Vreugde, S., . . . Kidd, S. P. (2023). The bacteriology of diabetic foot ulcers and infections and incidence of Staphylococcus aureus Small Colony Variants.. Journal of medical microbiology, 72(6), 001716-1-001716-11.
Scopus11 WoS3 Europe PMC92023 Mascarenhas, A. R., Vediappan, R. S., Jukes, A. K., Bouras, G., Kaukas, L. M., Chryssidis, S., . . . Wormald, P. -J. (2023). Haemostatic efficacy and inflammatory response of a novel beta-chitin patch in a cerebral small vessel injury model - A pilot study. Journal of Clinical Neuroscience, 114, 70-76.
2023 Bouras, G., Sheppard, A. E., Mallawaarachchi, V., & Vreugde, S. (2023). Plassembler: an automated bacterial plasmid assembly tool.. Bioinformatics (Oxford, England), 39(7), btad409.
Scopus21 Europe PMC282023 Cherian, L. M., Liu, S., Hon, K., Ramezanpour, M., Hu, H., Javadiyan, S., . . . Vreugde, S. (2023). Hydrocortisone metabolism by Staphylococcus: effects on anti-inflammatory and antimicrobial action.. International forum of allergy & rhinology, 14(3), 711-715.
Scopus1 Europe PMC12023 Pourmehran, O., Zarei, K., Pourchez, J., Vreugde, S., Psaltis, A., & Wormald, P. -J. (2023). Advancements in Acoustic Drug Delivery for Paranasal Sinuses: A Comprehensive Review. International Journal of Pharmaceutics, 644, 123277-1-123277-18.
Scopus7 Europe PMC22023 Feizi, S., Awad, M., Nepal, R., Cooksley, C. M., Psaltis, A. J., Wormald, P. -J., & Vreugde, S. (2023). Deferiprone-gallium-protoporphyrin (IX): A promising treatment modality against Mycobacterium abscessus.. Tuberculosis (Edinburgh, Scotland), 142, 102390.
Scopus12023 Shaghayegh, G., Cooksley, C., Bouras, G., Houtak, G., Nepal, R., Psaltis, A. J., . . . Vreugde, S. (2023). S. aureus biofilm metabolic activity correlates positively with patients’ eosinophil frequencies and disease severity in chronic rhinosinusitis. Microbes and Infection, 25(8), 105213-1-105213-10.
Scopus8 Europe PMC32023 Huang, S., Hon, K., Bennett, C., Hu, H., Menberu, M., Wormald, P. J., . . . Liu, S. (2023). Corrigendum: Corynebacterium accolens inhibits Staphylococcus aureus induced mucosal barrier disruption(Front. Microbiol., (2022), 13, (984741), 10.3389/fmicb.2022.984741). Frontiers in Microbiology, 14, 1279422.
2023 Houtak, G., Bouras, G., Nepal, R., Shaghayegh, G., Cooksley, C., Psaltis, A. J., . . . Vreugde, S. (2023). The intra-host evolutionary landscape and pathoadaptation of persistent Staphylococcus aureus in chronic rhinosinusitis. Microbial Genomics, 9(11), 001128-1-001128-21.
Scopus4 Europe PMC62022 Mahnaz, R., Harrison, B., Hon, K., Gohar, S., Hadi, R., Aaron, F. K., . . . Sarah, V. (2022). Characterization of human nasal organoids from chronic rhinosinusitis patients.. Biology open, 11(8), 1-8.
Scopus3 WoS1 Europe PMC32022 Sabab, A., Vediappan, R. S., Finnie, J., McAdam, C. J., Jukes, A., Vreugde, S., & Wormald, P. J. (2022). Efficacy and Safety of Novel Beta-Chitin Patches as Haemostat in Rat Vascular and Neurosurgical Model. Frontiers in Surgery, 9, 830364-1-830364-9.
Scopus2 WoS12022 Nepal, R., Houtak, G., Karki, S., Dhungana, G., Vreugde, S., & Malla, R. (2022). Genomic characterization of three bacteriophages targeting multidrug resistant clinical isolates of Escherichia, Klebsiella and Salmonella. Archives of Microbiology, 204(6), 1-9.
Scopus6 WoS2 Europe PMC72022 Liu, S., Hon, K., Bouras, G. S., Psaltis, A. J., Shearwin, K., Wormald, P. -J., & Vreugde, S. (2022). APTC-C-SA01: A Novel Bacteriophage Cocktail Targeting Staphylococcus aureus and MRSA Biofilms. International Journal of Molecular Sciences, 23(11), 6116-1-6116-18.
Scopus20 WoS3 Europe PMC132022 Shaghayegh, G., Cooksley, C., Ramezanpour, M., Wormald, P. -J., Psaltis, A. J., & Vreugde, S. (2022). Chronic Rhinosinusitis, S. aureus Biofilm and Secreted Products, Inflammatory Responses, and Disease Severity. Biomedicines, 10(6), 1-28.
Scopus26 WoS5 Europe PMC172022 Goggin, R. K., Bennett, C. A., Cooksley, C. M., Bassiouni, A., Bialasiewicz, S., Wormald, P. J., . . . Psaltis, A. J. (2022). Viral presence and the bacterial microbiome in chronic rhinosinusitis. Australian Journal of Otolaryngology, 5, 1-8.
Scopus12022 Huang, S., Hon, K., Bennett, C., Hu, H., Menberu, M., Wormald, P. -J., . . . Liu, S. (2022). Corynebacterium accolens inhibits Staphylococcus aureus induced mucosal barrier disruption. Frontiers in Microbiology, 13, 1-11.
Scopus17 Europe PMC172022 Lee, J., Carda-Diéguez, M., Žiemytė, M., Vreugde, S., Cooksley, C., Crosby, H. A., . . . Kidd, S. P. (2022). Functional
<i>mgrA</i>
Influences Genetic Changes within a Staphylococcus aureus Cell Population over Time. Journal of Bacteriology, 204(10), 21 pages.
Scopus8 WoS1 Europe PMC42022 Hon, K., Liu, S., Cooksley, C., Vreugde, S., & Psaltis, A. J. (2022). Low pH nasal rinse solution enhances mupirocin antimicrobial efficacy. Rhinology, 60(3), 218-228.
Scopus32022 Vediappan, R. S., Bennett, C., Cooksley, C., Bassiouni, A., Scott, J. R., Al Suliman, Y. A., . . . Wormald, P. -J. (2022). Wound healing in endoscopic sinus surgery - Phase 1 clinical trial evaluating the role of Chitogel with adjuvants.. Clin Otolaryngol, 48(2), 158-166.
Scopus6 WoS2 Europe PMC42022 Javadiyan, S., Cooksley, C. M., Bouras, G. S., Kao, S. S. T., Bennett, C. A., Wormald, P. J., . . . Psaltis, A. J. (2022). Investigation of Kappa Carrageenan's muco-adhesive, antibacterial, and anti-biofilm properties. International Forum of Allergy and Rhinology, 12(3), 302-305.
Scopus5 WoS1 Europe PMC32022 Menberu, M. A., Cooksley, C., Ramezanpour, M., Bouras, G., Wormald, P. -J., Psaltis, A. J., & Vreugde, S. (2022). In vitro and in vivo evaluation of probiotic properties of Corynebacterium accolens isolated from the human nasal cavity. Microbiological Research, 255, 10 pages.
Scopus11 WoS1 Europe PMC102022 Feizi, S., Cooksley, C. M., Nepal, R., Psaltis, A. J., Wormald, P. -J., & Vreugde, S. (2022). Silver nanoparticles as a bioadjuvant of antibiotics against biofilm-mediated infections with methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa in chronic rhinosinusitis patients. Pathology, 54(4), 453-459.
Scopus30 WoS6 Europe PMC162022 Shrestha, K., Van Strien, J., Shang, Y., Fletcher, D. F., Petersen, P., Vreugde, S., . . . Inthavong, K. (2022). Effect of breathing profiles on nebuliser drug delivery targeting the paranasal sinuses in a post-operative nasal cavity. Journal of Aerosol Science, 161, 1-19.
Scopus12 WoS52022 Hon, K., Liu, S., Camens, S., Bouras, G. S., Psaltis, A. J., Wormald, P. -J., & Vreugde, S. (2022). APTC-EC-2A: A Lytic Phage Targeting Multidrug Resistant E. coli Planktonic Cells and Biofilms. Microorganisms, 10(1), 1-18.
Scopus13 WoS4 Europe PMC82022 Nepal, R., Houtak, G., Wormald, P. -J., Psaltis, A. J., & Vreugde, S. (2022). Prophage: a crucial catalyst in infectious disease modulation. The Lancet Microbe, 3(3), e162-e163.
Scopus12 WoS1 Europe PMC102022 Hon, K., Liu, S., Cooksley, C., Vreugde, S., & Psaltis, A. J. (2022). Low pH nasal rinse solution enhances mupirocin antimicrobial efficacy.. Rhinology, 60(3), 218-228.
Europe PMC12022 Megow, A., Alsuliman, Y., Bouras, G., Menberu, M., Vyskocil, E., Vreugde, S., & Wormald, P. -J. (2022). Chitogel following endoscopic sinus surgery promotes a healthy microbiome and reduces post-operative infections.. International forum of allergy & rhinology, 12(11), 1362-1376.
Scopus7 WoS2 Europe PMC52022 Javadiyan, S., Germein, K. C., Cooksley, C. M., Ramezanpour, M., Singh, N., Wormald, P. -J., . . . Psaltis, A. J. (2022). In Vitro safety and anti-bacterial efficacy assessment of Acriflavine.. Allergy, 77(6), 1917-1920.
Scopus4 Europe PMC12022 Hu, H., Liu, S., Hon, K., Psaltis, A. J., Wormald, P. J., & Vreugde, S. (2022). Staphylococcal protein A modulates inflammation by inducing interferon signaling in human nasal epithelial cells. Inflammation Research, 72(2), 1-12.
Scopus4 WoS1 Europe PMC62021 Mabrouk, M. T., Chiem, K., Rujas, E., Huang, W. C., Jahagirdar, D., Quinn, B., . . . Lovell, J. (2021). Lyophilized, thermostable Spike or RBD immunogenic liposomes induce protective immunity against SARS-CoV-2 in mice. Science Advances, 7(49), eabj1476.
Scopus34 Europe PMC212021 Chan, J. C. Y., Waddell, T. K., Yasufuku, K., Keshavjee, S., & Donahoe, L. L. (2021). Maintaining technical proficiency in senior surgical fellows during the COVID-19 pandemic through virtual teaching. Jtcvs Open, 8, 679-687.
Scopus102021 Suzuki, M., Cooksley, C., Suzuki, T., Ramezanpour, M., Nakazono, A., Nakamaru, Y., . . . Vreugde, S. (2021). TLR Signals in Epithelial Cells in the Nasal Cavity and Paranasal Sinuses. Frontiers in Allergy, 2, 780425-1-780425-11.
Scopus12 WoS2 Europe PMC102021 Vahaji, S., Shang, Y., Zhang, Y., Wong, E., Rezk, A., Yeo, L., . . . Inthavong, K. (2021). Optimising Aerosol Delivery for Maxillary Sinus Deposition in a Post-FESS Sinonasal Cavities. AEROSOL AND AIR QUALITY RESEARCH, 21(12), 16 pages.
Scopus6 WoS22021 Nepal, R., Houtak, G., Shaghayegh, G., Bouras, G., Shearwin, K., Psaltis, A. J., . . . Vreugde, S. (2021). Prophages encoding human immune evasion cluster genes are enriched in Staphylococcus aureus isolated from chronic rhinosinusitis patients with nasal polyps. Microbial Genomics, 7(12), 000726-1-000726-19.
Scopus22 WoS8 Europe PMC162021 Ogi, K., Liu, S., Ramezanpour, M., Cooksley, C., Javadiyan, S., Fujieda, S., . . . Psaltis, A. J. (2021). Trimellitic anhydride facilitates transepithelial permeability disrupting tight junctions in sinonasal epithelial cells. Toxicology Letters, 353, 27-33.
Scopus4 WoS2 Europe PMC42021 Feizi, S., Javadiyan, S., Cooksley, C. M., Shaghayegh, G., Psaltis, A. J., Wormald, P., & Vreugde, S. (2021). Green synthesized colloidal silver is devoid of toxic effects on primary human nasal epithelial cells in vitro. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 157, 112606-1-112606-10.
Scopus9 WoS2 Europe PMC22021 Sabab, A., Vreugde, S., Jukes, A., & Wormald, P. J. (2021). The potential of chitosan-based haemostats for use in neurosurgical setting – Literature review. Journal of Clinical Neuroscience, 94, 128-134.
Scopus11 WoS5 Europe PMC22021 Ramezanpour, M., Bolt, H., Hon, K., Bouras, G. S., Psaltis, A. J., Wormald, P. J., & Vreugde, S. (2021). Cytokine-induced modulation of sars-cov2 receptor expression in primary human nasal epithelial cells. Pathogens, 10(7), 18 pages.
Scopus3 WoS2 Europe PMC22021 Ramezanpour, M., Ogi, K., Liu, S., Tuli, J. F., Bennett, C., Masanobu, S., . . . Vreugde, S. (2021). Der p 1 disrupts the epithelial barrier and induces IL-6 production in patients with house dust mite allergic rhinitis. Frontiers in Allergy, 2, 692049-1-692049-9.
Scopus16 WoS5 Europe PMC112021 Rastin, H., Mansouri, N., Tung, T. T., Hassan, K., Mazinani, A., Ramezanpour, M., . . . Losic, D. (2021). Converging 2D nanomaterials and 3D bioprinting technology: state-of-the-art, challenges, and potential outlook in biomedical applications. Advanced Healthcare Materials, 10(22), e2101439-1-e2101439-50.
Scopus27 WoS9 Europe PMC72021 Sabab, A., Liu, S., Javadiyan, S., McAdam, C. J., Hanton, L. R., Jukes, A., . . . Wormald, P. -J. (2021). The effect of chemical and structural modifiers on the haemostatic process and cytotoxicity of the beta-chitin patch. Scientific Reports, 11(1), 1-15.
Scopus4 WoS2 Europe PMC22021 Camens, S., Hon, K., Liu, S., Bouras, G. S., Psaltis, A. J., Wormald, P., & Vreugde, S. (2021). Preclinical Development of a Bacteriophage Cocktail for Treating Multidrug Resistant Pseudomonas aeruginosa Infections. Microorganisms, 9(9), 2001-1-2001-16.
Scopus15 WoS6 Europe PMC122021 Menberu, M. A., Hayes, A. J., Liu, S., Psaltis, A. J., Wormald, P. -J., & Vreugde, S. (2021). Tween 80 and its derivative oleic acid promote the growth of Corynebacterium accolens and inhibit Staphylococcus aureus clinical isolates. Int Forum Allergy Rhinol, 11(4), 810-813.
Scopus9 WoS5 Europe PMC82021 Vediappan, R. S., Bennett, C., Cooksley, C., Finnie, J., Trochsler, M., Quarrington, R. D., . . . Wormald, P. J. (2021). Prevention of adhesions post-abdominal surgery: Assessing the safety and efficacy of Chitogel with Deferiprone in a rat model. PLoS One, 16(1), e0244503-1-e0244503-17.
Scopus7 WoS4 Europe PMC42021 Suzuki, M., Ramezanpour, M., Cooksley, C., Ogi, K., Psaltis, A. J., Nakamaru, Y., . . . Vreugde, S. (2021). Metallothionein-3 is a clinical biomarker for tissue zinc levels in nasal mucosa. Auris Nasus Larynx, 48(5), 890-897.
Scopus4 WoS1 Europe PMC42021 Menberu, M. A., Liu, S., Cooksley, C., Hayes, A. J., Psaltis, A. J., Wormald, P. -J., & Vreugde, S. (2021). Corynebacterium accolens Has Antimicrobial Activity against Staphylococcus aureus and Methicillin-Resistant S. aureus Pathogens Isolated from the Sinonasal Niche of Chronic Rhinosinusitis Patients. Pathogens, 10(2), 1-19.
Scopus47 WoS21 Europe PMC402021 Feizi, S., Cooksley, C. M., Bouras, G. S., Prestidge, C. A., Coenye, T., Psaltis, A. J., . . . Vreugde, S. (2021). Colloidal silver combating pathogenic Pseudomonas aeruginosa and MRSA in chronic rhinosinusitis.. Colloids and surfaces. B, Biointerfaces, 202, 1-10.
Scopus16 WoS13 Europe PMC112021 Rastin, H., Ramezanpour, M., Hassan, K., Mazinani, A., Tung, T. T., Vreugde, S., & Losic, D. (2021). 3D bioprinting of a cell-laden antibacterial polysaccharide hydrogel composite. Carbohydrate Polymers, 264, 117989-1-117989-12.
Scopus69 WoS42 Europe PMC282021 Liu, S., Zhao, Y., Hayes, A., Hon, K., Zhang, G., Bennett, C., . . . Vreugde, S. (2021). Overcoming bacteriophage insensitivity in Staphylococcus aureus using clindamycin and azithromycinat sub-inhibitory concentrations. Allergy, 76(11), 3446-3458.
Scopus12 WoS5 Europe PMC92021 Nakazono, A., Nakamaru, Y., Ramezanpour, M., Kondo, T., Watanabe, M., Hatakeyama, S., . . . Homma, A. (2021). Fluticasone Propionate Suppresses Poly(I:C)-Induced ACE2 in Primary Human Nasal Epithelial Cells. Frontiers in Cellular and Infection Microbiology, 11, 1-10.
Scopus13 WoS11 Europe PMC102021 Tuli, J. F., Ramezanpour, M., Cooksley, C., Psaltis, A. J., Wormald, P. -J., & Vreugde, S. (2021). Association between mucosal barrier disruption by Pseudomonas aeruginosa exoproteins and asthma in patients with chronic rhinosinusitis.. Allergy, 76(11), 3459-3469.
Scopus27 WoS12 Europe PMC192021 Cherian, L. M., Bassiouni, A., Cooksley, C. M., Vreugde, S., Wormald, P., & Psaltis, A. J. (2021). The clinical outcomes of medical therapies in chronic rhinosinusitis is independent of microbiomic outcomes: a double-blinded, randomised placebo-controlled trial.. Rhinology, 58(3), 386-390.
Scopus13 WoS9 Europe PMC82021 Kao, S., Bassiouni, A., Ramezanpour, M., Finnie, J., Chegeni, N., Colella, A. D., . . . Psaltis, A. J. (2021). Proteomic analysis of nasal mucus samples of healthy and chronic rhinosinusitis patients. Journal of Allergy and Clinical Immunology, 147(1), 168-178.
Scopus39 WoS22 Europe PMC292021 Connell, J., Bassiouni, A., Wormald, P., Vreugde, S., & Psaltis, A. (2021). Optimal primer selection for sinus microbiome profiling: A comparative analysis of the V1‐V3 and V3‐4 16S target regions. International Forum of Allergy & Rhinology, 11(12), 1698-1702.
Scopus5 Europe PMC32021 Mazinani, A., Rastin, H., Nine, M. J., Lee, J., Tikhomirova, A., Tung, T. T., . . . Losic, D. (2021). Comparative antibacterial activity of 2D materials coated on the porous-titania. Journal of Materials Chemistry B, 32(32), 6412-6424.
Scopus19 WoS8 Europe PMC92021 Pourmehran, O., Arjomandi, M., Cazzolato, B., Tian, Z., Vreugde, S., Javadiyan, S., . . . Wormald, P. -J. (2021). Acoustic drug delivery to the maxillary sinus.. Int J Pharm, 606, 1-15.
Scopus21 WoS12 Europe PMC82020 Ooi, M. L., Drilling, A. J., James, C., Moratti, S., Vreugde, S., Psaltis, A. J., & Wormald, P. J. (2020). Efficacy of anti-biofilm gel, chitogel-mupirocin-budesonide in a sheep sinusitis model. Australian Journal of Otolaryngology(Hong Kong), 3(May), 8 pages.
Scopus12020 Ramezanpour, M., Hu, H., Lau, A., Liu, S., De Silva, A., Bolt, H., . . . Vreugde, S. (2020). Increased serum IgG4 associates with asthma and tissue eosinophilia in chronic rhinosinusitis patients. Pathogens, 9(10), 1-6.
Scopus4 WoS1 Europe PMC32020 Suzuki, M., Suzuki, T., Watanabe, M., Hatakeyama, S., Kimura, S., Nakazono, A., . . . Homma, A. (2020). Role of intracellular zinc in molecular and cellular function in allergic inflammatory diseases. Allergology International, 70(2), 190-200.
Scopus27 Europe PMC252020 Paramasivan, S., Psaltis, A. J., Wormald, P. J., & Vreugde, S. (2020). Tertiary Lymphoid Organs: A Primer for Otolaryngologists.. Laryngoscope, 131(8), 1697-1703.
Scopus2 WoS1 Europe PMC12020 Suzuki, M., Ramezanpour, M., Cooksley, C., Lee, T. J., Jeong, B., Kao, S., . . . Vreugde, S. (2020). Zinc-depletion associates with tissue eosinophilia and collagen depletion in chronic rhinosinusitis. Rhinology, 58(5), 451-459.
Scopus15 WoS3 Europe PMC112020 Kao, S. S. T., Ramezanpour, M., Bassiouni, A., Finnie, J., Wormald, P. J., Vreugde, S., & Psaltis, A. J. (2020). Barrier disruptive effects of mucus isolated from chronic rhinosinusitis patients. Allergy, 75(1), 200-203.
Scopus12 WoS13 Europe PMC72020 Curragh, D. S., Bassiouni, A., Macias-Valle, L., Vreugde, S., Wormald, P. -J., Selva, D., & Psaltis, A. J. (2020). The Microbiome of the Nasolacrimal System and Its Role in Nasolacrimal Duct Obstruction. Ophthalmic plastic and reconstructive surgery, 36(1), 80-85.
Scopus13 WoS5 Europe PMC62020 Dong, D., Thomas, N., Ramezanpour, M., Alkis, P., Huang, S., Zhao, Y., . . . Vreudge, S. (2020). Inhibition of Staphylococcus aureus and Pseudomonas aeruginosa biofilms by quatsomes in low concentrations. Experimental Biology and Medicine, 245(1), 34-41.
Scopus16 WoS14 Europe PMC102020 Vediappan, R. S., Mascarenhas, A., Nguyen-Hoang, A., Fong, S. A., Jukes, A., Richter, K., . . . Wormald, P. (2020). Prevention of peridural adhesions in spinal surgery: assessing safety and efficacy of Chitogel with Deferiprone in a sheep model. Journal of Clinical Neuroscience, 72, 378-385.
Scopus12 WoS5 Europe PMC72020 Bassiouni, A., Ou, J., Schreiber, A., Geoghegan, J., Tsykin, A., Psaltis, A. J., . . . Vreugde, S. (2020). The global transcriptomic signature in sinonasal tissues reveals roles for tissue type and chronic rhinosinusitis disease phenotype. Rhinology, 58(3), 273-283.
Scopus12 WoS8 Europe PMC72020 Paramasivan, S., Bassiouni, A., Shiffer, A., Dillon, M. R., Cope, E. K., Cooksley, C., . . . Psaltis, A. J. (2020). The international sinonasal microbiome study (ISMS): a multi-centre, multi-national characterization of sinonasal bacterial ecology. Allergy, 75(8), 2033-2045.
Scopus66 WoS38 Europe PMC502020 Gouzos, M., Ramezanpour, M., Bassiouni, A., Psaltis, A. J., Wormald, P. J., & Vreugde, S. (2020). Antibiotics affect ROS production and fibroblast migration in an in-vitro model of sinonasal wound healing. Frontiers in Cellular and Infection Microbiology, 10, 110-1-110-12.
Scopus20 WoS8 Europe PMC142020 Bassiouni, A., Paramasivan, S., Shiffer, A., Dillon, M. R., Cope, E. K., Cooksley, C., . . . Psaltis, A. J. (2020). Microbiotyping the Sinonasal Microbiome.. Frontiers in Cellular and Infection Microbiology, 10, 137.
Scopus30 WoS12 Europe PMC232020 Vediappan, R. S., Bennett, C., Bassiouni, A., Smith, M., Finnie, J., Trochsler, M., . . . Wormald, P. J. (2020). A novel rat model to test intra-abdominal anti-adhesive therapy. Frontiers in Surgery, 7, 12.
Scopus10 WoS5 Europe PMC52020 Goggin, R., Bennett, C., Ramezanpour, M., Hu, H., Fenix, K., Bassiouni, A., . . . Vreugde, S. (2020). Association between viral infection and increased mucosal eosinophils and CD8<sup>+</sup>CD103<sup>+</sup> T cells in chronic rhinosinusitis. International Forum of Allergy and Rhinology, 10(8), 978-980.
2020 Ramezanpour, M., Smith, J. P., Pstaltis, A. J., Wormald, P. J., & Vreugde, S. (2020). In vitro safety evaluation of a povidone‐iodine solution applied to human nasal epithelial cells. International Forum of Allergy and Rhinology, 10(10), 1141-1148.
Scopus33 WoS23 Europe PMC212020 Ramezanpour, M., Kao, S., Bassiouni, A., Chegeni, N., Colella, A., Chataway, K., . . . Psaltis, A. (2020). Scoping review of chronic rhinosinusitis proteomicsc rhinosinusitis proteomics. Rhinology, 58(5), 418-470.
2020 Panchatcharam, B. S., Cooksley, C. M., Ramezanpour, M., Vediappan, R. S., Bassiouni, A., Wormald, P. J., . . . Vreugde, S. (2020). Staphylococcus aureus biofilm exoproteins are cytotoxic to human nasal epithelial barrier in Chronic Rhinosinusitis. International Forum of Allergy and Rhinology, 10(7), 871-883.
Scopus25 WoS14 Europe PMC152020 Kao, S. S. -T., Bassiouni, A., Ramezanpour, M., Chegeni, N., Colella, A. D., Chataway, T. K., . . . Psaltis, A. J. (2020). Scoping review of chronic rhinosinusitis proteomics.. Rhinology, 58(5), 418-470.
Scopus17 WoS9 Europe PMC112019 Ooi, M. L., Drilling, A. J., Morales, S., Fong, S., Moraitis, S., MacIas-Valle, L., . . . Wormald, P. J. (2019). Safety and tolerability of bacteriophage therapy for chronic rhinosinusitis due to staphylococcus aureus. JAMA Otolaryngology-Head and Neck Surgery, 145(8), 723-729.
Scopus132 WoS68 Europe PMC1002019 Govindaraju, R., Cherian, L., Macias-Valle, L., Murphy, J., Gouzos, M., Vreugde, S., . . . Psaltis, A. J. (2019). Extent of maxillary sinus surgery and its effect on instrument access, irrigation penetration, and disease clearance. International Forum of Allergy and Rhinology, 9(10), 1097-1104.
Scopus17 WoS13 Europe PMC122019 Kao, S. S. T., Ramezanpour, M., Bassiouni, A., Wormald, P. J., Psaltis, A. J., & Vreugde, S. (2019). The effect of neutrophil serine proteases on human nasal epithelial cell barrier function. International Forum of Allergy and Rhinology, 9(10), 7 pages.
Scopus33 WoS20 Europe PMC232019 Ooi, M. L., Jothin, A., Bennett, C., Ooi, E. H., Vreugde, S., Psaltis, A. J., & Wormald, P. J. (2019). Manuka honey sinus irrigations in recalcitrant chronic rhinosinusitis: phase 1 randomized, single-blinded, placebo-controlled trial. International Forum of Allergy and Rhinology, 9(12), 1470-1477.
Scopus25 WoS17 Europe PMC142019 Hu, H., Ramezanpour, M., Hayes, A. J., Liu, S., Psaltis, A. J., Wormald, P., & Vreugde, S. (2019). Sub-Inhibitory Clindamycin and Azithromycin reduce S. aureus Exoprotein Induced Toxicity, Inflammation, Barrier Disruption and Invasion.. Journal of clinical medicine, 8(10), 16 pages.
Scopus17 WoS14 Europe PMC142019 Murphy, J., Ramezanpour, M., Drilling, A., Roscioli, E., Psaltis, A. J., Wormald, P. J., & Vreugde, S. (2019). In vitro characteristics of an airway barrier-disrupting factor secreted by Staphylococcus aureus. International Forum of Allergy and Rhinology, 9(2), 187-196.
Scopus12 WoS9 Europe PMC82019 Fong, S. A., Drilling, A. J., Ooi, M. L., Paramasivan, S., Finnie, J. W., Morales, S., . . . Wormald, P. J. (2019). Safety and efficacy of a bacteriophage cocktail in an in vivo model of Pseudomonas aeruginosa sinusitis. Translational Research, 206, 41-56.
Scopus39 WoS22 Europe PMC292019 Ramezanpour, M., Bolt, H., Psaltis, A., Wormald, P. J., & Vreugde, S. (2019). Inducing a Mucosal Barrier–Sparing Inflammatory Response in Laboratory-Grown Primary Human Nasal Epithelial Cells. Current Protocols in Toxicology, 80(1), e69.
Scopus15 Europe PMC92019 Cherian, L. M., Cooksley, C., Richter, K., Ramezanpour, M., Paramasivan, S., Wormald, P. J., . . . Psaltis, A. J. (2019). Effect of commercial nasal steroid preparation on bacterial growth. International Forum of Allergy and Rhinology, 9(7), 766-775.
Scopus10 WoS7 Europe PMC42019 Ramezanpour, M., Smith, J. L. P., Ooi, M. L., Gouzos, M., Psaltis, A. J., Wormald, P. J., & Vreugde, S. (2019). Deferiprone has anti-inflammatory properties and reduces fibroblast migration in vitro. Scientific Reports, 9(1), 9 pages.
Scopus24 WoS12 Europe PMC212019 Li, J., Ramezanpour, M., Fong, S. A., Cooksley, C., Murphy, J., Suzuki, M., . . . Vreugde, S. (2019). Pseudomonas aeruginosa exoprotein-induced barrier disruption correlates with elastase activity and marks Chronic Rhinosinusitis severity. Frontiers in Cellular and Infection Microbiology, 9, 9 pages.
Scopus31 WoS20 Europe PMC222019 Goggin, R. K., Bennett, C. A., Bialasiewicz, S., Vediappan, R. S., Vreugde, S., Wormald, P. J., & Psaltis, A. J. (2019). The presence of virus significantly associates with chronic rhinosinusitis disease severity. Allergy European Journal of Allergy and Clinical Immunology, 74(8), 1569-1572.
Scopus18 WoS11 Europe PMC122019 Bennett, C., Ramezanpour, M., Cooksley, C., Vreugde, S., & Psaltis, A. J. (2019). Kappa-carrageenan sinus rinses reduce inflammation and intracellular Staphylococcus aureus infection in airway epithelial cells. International Forum of Allergy and Rhinology, 9(8), 918-925.
Scopus11 WoS7 Europe PMC52018 Ooi, M., Richter, K., Bennett, C., Macias-Valle, L., Vreugde, S., Psaltis, A., & Wormald, P. (2018). Topical colloidal silver for the treatment of recalcitrant chronic rhinosinusitis. Frontiers in Microbiology, 9(APR), 1-7.
Scopus20 WoS15 Europe PMC122018 Ooi, M., Richter, K., Drilling, A., Thomas, N., Prestidge, C. A., James, C., . . . Wormald, P. J. (2018). Safety and efficacy of topical chitogel- deferiprone- gallium protoporphyrin in a sheep sinusitis model. Frontiers in Microbiology, 9(MAY), 9 pages.
Scopus16 WoS12 Europe PMC122018 Suzuki, M., Ramezanpour, M., Cooksley, C., Li, J., Nakamaru, Y., Homma, A., . . . Vreugde, S. (2018). Sirtuin-1 Controls Poly (I:C)-Dependent Matrix Metalloproteinase 9 Activation in Primary Human Nasal Epithelial Cells. American journal of respiratory cell and molecular biology, 59(4), 500-510.
Scopus16 WoS16 Europe PMC132018 Murphy, J., Ramezanpour, M., Roscioli, E., Psaltis, A. J., Wormald, P. J., & Vreugde, S. (2018). Mucosal zinc deficiency in chronic rhinosinusitis with nasal polyposis contributes to barrier disruption and decreases ZO-1. Allergy European Journal of Allergy and Clinical Immunology, 73(10), 2095-2097.
Scopus27 WoS18 Europe PMC172018 Ramezanpour, M., Bolt, H., Psaltis, A., Wormald, P., & Vreugde, S. (2018). Primary human nasal epithelial cells: a source of poly (I:C) LMW-induced IL-6 production. Scientific Reports, 8(1), 8 pages.
Scopus26 WoS19 Europe PMC222018 Zhang, G., Zhao, Y., Hayes, A. J., Psaltis, A. J., Wormald, P. J., & Vreugde, S. (2018). Staphylococcus aureus small colony variants: Prevalence in chronic rhinosinusitis and induction by antibiotics. Allergy European Journal of Allergy and Clinical Immunology, 73(12), 2403-2405.
Scopus6 WoS4 Europe PMC42018 Paramasivan, S., Lester, S., Lau, A., Ou, J., Psaltis, A., Wormald, P., & Vreugde, S. (2018). Tertiary lymphoid organs: A novel target in patients with chronic rhinosinusitis. Journal of Allergy and Clinical Immunology, 142(5), 1673-1676.
Scopus12 WoS8 Europe PMC52018 Goggin, R., Bennett, C., Bassiouni, A., Bialasiewicz, S., Vreugde, S., Wormald, P., & Psaltis, A. (2018). Comparative viral sampling in the sinonasal passages; Different viruses at different sites. Frontiers in Cellular and Infection Microbiology, 8(SEP), 8 pages.
Scopus9 WoS7 Europe PMC62018 Bardy, J., Sarovich, D., Price, E., Steinig, E., Tong, S., Drilling, A., . . . Psaltis, A. (2018). Staphylococcus aureus from patients with chronic rhinosinusitis show minimal genetic association between polyp and non-polyp phenotypes 06 Biological Sciences 0604 Genetics. BMC Ear, Nose and Throat Disorders, 18(1), 8 pages.
Scopus9 WoS6 Europe PMC62018 Zhao, Y., Bassiouni, A., Tanjararak, K., Vreugde, S., Wormald, P., & Psaltis, A. (2018). Role of fungi in chronic rhinosinusitis through ITS sequencing. Laryngoscope, 128(1), 16-22.
Scopus40 WoS23 Europe PMC252018 Murphy, J., Ramezanpour, M., Stach, N., Dubin, G., Psaltis, A., Wormald, P., & Vreugde, S. (2018). Staphylococcus Aureus V8 protease disrupts the integrity of the airway epithelial barrier and impairs IL-6 production in vitro. Laryngoscope, 128(1), 8-15.
Scopus45 WoS31 Europe PMC292018 Zhang, G., Zhao, Y., Paramasivan, S., Richter, K., Morales, S., Wormald, P., & Vreugde, S. (2018). Bacteriophage effectively kills multidrug resistant Staphylococcus aureus clinical isolates from chronic rhinosinusitis patients. International Forum of Allergy and Rhinology, 8(3), 406-414.
Scopus41 WoS31 Europe PMC302018 Miljkovic, D., Psaltis, A., Wormald, P., & Vreugde, S. (2018). Naive and effector B-cell subtypes are increased in chronic rhinosinusitis with polyps. American Journal of Rhinology and Allergy, 32(1), 3-6.
Scopus15 WoS8 Europe PMC92017 Miljkovic, D., Psaltis, A., Wormald, P., & Vreugde, S. (2017). Chronic rhinosinusitis with polyps is characterized by increased mucosal and blood Th17 effector cytokine producing cells. Frontiers in Physiology, 8(DEC), 7 pages.
Scopus13 WoS9 Europe PMC122017 Fong, S., Drilling, A., Morales, S., Cornet, M., Woodworth, B., Fokkens, W., . . . Wormald, P. (2017). Activity of bacteriophages in removing biofilms of pseudomonas aeruginosa isolates from chronic rhinosinusitis patients. Frontiers in Cellular and Infection Microbiology, 7(SEP), 1-11.
Scopus132 WoS97 Europe PMC942017 Ramezanpour, M., Murphy, J., Smith, J., Vreugde, S., & Psaltis, A. (2017). In vitro safety evaluation of human nasal epithelial cell monolayers exposed to carrageenan sinus wash. International Forum of Allergy and Rhinology, 7(12), 1170-1177.
Scopus24 WoS19 Europe PMC102017 Oue, S., Ramezanpour, M., Paramasivan, S., Miljkovic, D., Cooksley, C. M., Bassiouni, A., . . . Vreugde, S. (2017). Increased IL-13 expression is independently associated with neo-osteogenesis in patients with chronic rhinosinusitis. Journal of Allergy and Clinical Immunology, 140(5), 1444-1448.e11.
Scopus12 WoS11 Europe PMC82017 Richter, K., Facal, P., Thomas, N., Vandecandelaere, I., Ramezanpour, M., Cooksley, C., . . . Vreugde, S. (2017). Taking the silver bullet colloidal silver particles for the topical treatment of biofilm-related infections. ACS Applied Materials and Interfaces, 9(26), 21631-21638.
Scopus48 WoS40 Europe PMC232017 Richter, K., Thomas, N., Zhang, G., Prestidge, C., Coenye, T., Wormald, P. -J., & Vreugde, S. (2017). Deferiprone and gallium-protoporphyrin have the capacity to potentiate the activity of antibiotics in Staphylococcus aureus small colony variants. Frontiers in Cellular and Infection Microbiology, 7(JUN), 280-1-280-10.
Scopus53 WoS36 Europe PMC292017 Ou, J., Bassiouni, A., Drilling, A., Psaltis, A., Vreugde, S., & Wormald, P. (2017). The persistence of intracellular Staphylococcus aureus in the sinuses: a longitudinal study.. Rhinology, 55(4), 305-311.
Scopus19 WoS14 Europe PMC102017 Ramezanpour, M., Rayan, A., Smith, J., & Vreugde, S. (2017). The effect of topical treatments for CRS on the sinonasal epithelial barrier. Rhinology, 55(2), 161-169.
Scopus14 WoS11 Europe PMC102017 Chan, C., Richter, K., Wormald, P., Psaltis, A., & Vreugde, S. (2017). Alloiococcus otitidis forms multispecies biofilm with Haemophilus influenzae: effects on antibiotic susceptibility and Growth in Adverse Conditions. Frontiers in Cellular and Infection Microbiology, 7(AUG), 344-1-344-9.
Scopus25 WoS17 Europe PMC152017 Jukes, A., Murphy, J., Vreugde, S., Psaltis, A., & Wormald, P. (2017). Nano-hemostats and a Pilot Study of Their Use in a Large Animal Model of Major Vessel Hemorrhage in Endoscopic Skull Base Surgery. Journal of Neurological Surgery, Part B: Skull Base, 78(3), 215-221.
Scopus2 WoS2 Europe PMC12017 Lau, A., Lester, S., Moraitis, S., Ou, J., Psaltis, A., McColl, S., . . . Vreugde, S. (2017). Tertiary lymphoid organs in recalcitrant chronic rhinosinusitis. Journal of Allergy and Clinical Immunology, 139(4), 1371-1373.
Scopus25 WoS18 Europe PMC152017 Miljkovic, D., Ou, J., Kirana, C., Hulse, K., Hauben, E., Psaltis, A., . . . Vreugde, S. (2017). Discordant frequencies of tissue-resident and circulating CD180-negative B cells in chronic rhinosinusitis. International Forum of Allergy and Rhinology, 7(6), 609-614.
Scopus4 WoS4 Europe PMC22017 Drilling, A., Ooi, M., Miljkovic, D., James, C., Speck, P., Vreugde, S., . . . Wormald, P. (2017). Long-term safety of topical bacteriophage application to the frontal sinus region. Frontiers in Cellular and Infection Microbiology, 7(FEB), 1-8.
Scopus42 WoS30 Europe PMC292017 Chan, C., Wabnitz, D., Bassiouni, A., Wormald, P., Vreugde, S., & Psaltis, A. (2017). Identification of the bacterial reservoirs for the middle ear using phylogenic analysis. JAMA Otolaryngology - Head and Neck Surgery, 143(2), 155-161.
Scopus29 WoS23 Europe PMC212017 Richter, K., Thomas, N., Claeys, J., McGuane, J., Prestidge, C., Coenye, T., . . . Vreugde, S. (2017). A topical hydrogel with deferiprone and gallium-protoporphyrin targets bacterial iron metabolism and has antibiofilm activity. Antimicrobial Agents and Chemotherapy, 61(6), e00481-17-1-e00481-17-11.
Scopus70 WoS51 Europe PMC402016 Chan, C., Wabnitz, D., Bardy, J., Bassiouni, A., Wormald, P., Vreugde, S., & Psaltis, A. (2016). The microbiome of otitis media with effusion. Laryngoscope, 126(12), 2844-2851.
Scopus56 WoS48 Europe PMC392016 Vreugde, S., & Wormald, P. (2016). Innate lymphoid type 2 cells in chronic rhinosinusitis. Current Opinion in Allergy and Clinical Immunology, 16(1), 7-12.
Scopus6 WoS4 Europe PMC32016 Bassiouni, A., Ou, J., Rajiv, S., Cantero, D., Vreugde, S., & Wormald, P. (2016). Subepithelial inflammatory load and basement membrane thickening in refractory chronic rhinosinusitis with nasal polyposis: A histopathological study. International Forum of Allergy and Rhinology, 6(3), 248-255.
Scopus37 WoS30 Europe PMC282016 Drilling, A., Cooksley, C., Chan, C., Wormald, P., & Vreugde, S. (2016). Fighting sinus-derived Staphylococcus aureus biofilms in vitro with a bacteriophage-derived muralytic enzyme. International Forum of Allergy and Rhinology, 6(4), 349-355.
Scopus26 WoS21 Europe PMC182016 Cleland, E., Bassiouni, A., Vreugde, S., & Wormald, P. (2016). The bacterial microbiome in chronic rhinosinusitis: Richness, diversity, postoperative changes, and patient outcomes. American Journal of Rhinology and Allergy, 30(1), 37-43.
Scopus61 WoS45 Europe PMC432016 Richter, K., Ramezanpour, M., Thomas, N., Prestidge, C. A., Wormald, P. J., & Vreugde, S. (2016). Mind “De GaPP”: in vitro efficacy of deferiprone and gallium-protoporphyrin against Staphylococcus aureus biofilms. International Forum of Allergy and Rhinology, 6(7), 737-743.
Scopus45 WoS37 Europe PMC322016 Ramezanpour, M., Moraitis, S., Smith, J., Wormald, P., & Vreugde, S. (2016). Th17 cytokines disrupt the airway mucosal barrier in chronic rhinosinusitis. Mediators of Inflammation, 2016, 9798206-1-9798206-7.
Scopus70 WoS49 Europe PMC482016 Miljkovic, D., Psaltis, A., Wormald, P., & Vreugde, S. (2016). T regulatory and Th17 cells in chronic rhinosinusitis with polyps. International Forum of Allergy and Rhinology, 6(8), 826-834.
Scopus25 WoS13 Europe PMC132016 Ou, J., Drilling, A., Singhal, D., Tan, N., Wallis-Hill, D., Vreugde, S., . . . Wormald, P. (2016). Association of intracellular Staphylococcus aureus with prognosis in chronic rhinosinusitis. International Forum of Allergy and Rhinology, 6(8), 792-799.
Scopus29 WoS22 Europe PMC222016 Ou, J., Drilling, A., Cooksley, C., Bassiouni, A., Kidd, S., Psaltis, A., . . . Vreugde, S. (2016). Reduced innate immune response to a Staphylococcus aureus small colony variant compared to its wild-type parent strain. Frontiers in Cellular and Infection Microbiology, 6(DEC), 187-1-187-9.
Scopus23 WoS21 Europe PMC212016 Hasan, S., Thomas, N., Thierry, B., Vreugde, S., Wormald, P., & Prestidge, C. (2016). Recent trends on the use of nanoparticles for nitric oxide delivery in antimicrobial applications. Drug Delivery Letters, 6(1), 3-10.
Scopus22015 Cantero, D., Cooksley, C., Bassiouni, A., Tran, H., Roscioli, E., Wormald, P., & Vreugde, S. (2015). Staphylococcus aureus biofilms induce apoptosis and expression of interferon-γ, interleukin-10, and interleukin-17A on human sinonasal explants. American Journal of Rhinology and Allergy, 29(1), 23-28.
Scopus20 WoS14 Europe PMC102015 Rajiv, S., Drilling, A., Bassiouni, A., James, C., Vreugde, S., & Wormald, P. (2015). Topical colloidal silver as an anti-biofilm agent in a Staphylococcus aureus chronic rhinosinusitis sheep model. International Forum of Allergy and Rhinology, 5(4), 283-288.
Scopus23 WoS19 Europe PMC142015 Malik, Z., Roscioli, E., Murphy, J., Ou, J., Bassiouni, A., Wormald, P., & Vreugde, S. (2015). Staphylococcus aureus impairs the airway epithelial barrier in vitro. International Forum of Allergy and Rhinology, 5(6), 551-556.
Scopus62 WoS46 Europe PMC432015 Bassiouni, A., Cleland, E., Psaltis, A., Vreugde, S., & Wormald, P. (2015). Sinonasal microbiome sampling: a comparison of techniques. PLoS One, 10(4), e0123216-1-e0123216-13.
Scopus46 WoS48 Europe PMC432015 Rajiv, S., Rodgers, S., Bassiouni, A., Vreugde, S., & Wormald, P. (2015). Role of crushed skeletal muscle extract in hemostasis. International Forum of Allergy & Rhinology, 5(5), 431-434.
Scopus4 WoS4 Europe PMC42015 Jardeleza, C., Thierry, B., Rao, S., Rajiv, S., Drilling, A., Miljkovic, D., . . . Wormald, P. (2015). An in vivo safety and efficacy demonstration of a topical liposomal nitric oxide donor treatment for Staphylococcus aureus biofilm-associated rhinosinusitis. Translational Research, 166(6), 683-692.
Scopus32 WoS22 Europe PMC202015 Dong, D., Thomas, N., Thierry, B., Vreugde, S., Prestidge, C., & Wormald, P. (2015). Distribution and Inhibition of liposomes on Staphylococcus aureus and Pseudomonas aeruginosa biofilm. PLoS One, 10(6), e0131806.
Scopus78 WoS60 Europe PMC422015 Thomas, N., Dong, D., Richter, K., Ramezanpour, M., Vreugde, S., Thierry, B., . . . Prestidge, C. (2015). Quatsomes for the treatment of Staphylococcus aureus biofilm. Journal of Materials Chemistry B, 3(14), 2770-2777.
Scopus28 WoS23 Europe PMC102015 Cooksley, C., Roscioli, E., Wormald, P., & Vreugde, S. (2015). TLR response pathways in NuLi-1 cells and primary human nasal epithelial cells. Molecular Immunology, 68(2 part B), 476-483.
Scopus20 WoS16 Europe PMC152014 Tan, N., Cooksley, C., Roscioli, E., Drilling, A., Douglas, R., Wormald, P., & Vreugde, S. (2014). Small-colony variants and phenotype switching of intracellular Staphylococcus aureus in chronic rhinosinusitis. Allergy, 69(10), 1364-1371.
Scopus37 WoS36 Europe PMC312014 Miljkovic, D., Bassiouni, A., Cooksley, C., Ou, J., Hauben, E., Wormald, P., & Vreugde, S. (2014). Association between group 2 innate lymphoid cells enrichment, nasal polyps and allergy in chronic rhinosinusitis. Allergy, 69(9), 1154-1161.
Scopus152 WoS126 Europe PMC1262014 Padhye, V., Valentine, R., Paramasivan, S., Jardeleza, C., Bassiouni, A., Vreugde, S., & Wormald, P. (2014). Early and late complications of endoscopic hemostatic techniques following different carotid artery injury characteristics. International Forum of Allergy and Rhinology, 4(8), 651-657.
Scopus35 WoS29 Europe PMC272014 Cleland, E., Drilling, A., Bassiouni, A., James, C., Vreugde, S., & Wormald, P. (2014). Probiotic manipulation of the chronic rhinosinusitis microbiome. International Forum of Allergy and Rhinology, 4(4), 309-314.
Scopus45 WoS38 Europe PMC382014 Cleland, E., Bassioni, A., Boase, S., Dowd, S., Vreugde, S., & Wormald, P. (2014). The fungal microbiome in chronic rhinosinusitis: richness, diversity, postoperative changes and patient outcomes. International Forum of Allergy and Rhinology, 4(4), 259-265.
Scopus68 WoS52 Europe PMC522014 Drilling, A., Morales, S., Jardeleza, C., Vreugde, S., Speck, P., & Wormald, P. (2014). Bacteriophage reduces biofilm of Staphylococcus aureus ex vivo isolates from chronic rhinosinusitis patients. American Journal of Rhinology and Allergy, 28(1), 3-11.
Scopus58 WoS49 Europe PMC432014 Drilling, A., Coombs, G., Tan, H., Pearson, J., Boase, S., Psaltis, A., . . . Wormald, P. (2014). Cousins, siblings, or copies: the genomics of recurrent Staphylococcus aureus infections in chronic rhinosinusitis. International Forum of Allergy and Rhinology, 4(12), 953-960.
Scopus24 WoS19 Europe PMC202014 Jardeleza, C., Rao, S., Thierry, B., Gajjar, P., Vreugde, S., Prestidge, C., & Wormald, P. (2014). Liposome-encapsulated ISMN: a novel nitric oxide-based therapeutic agent against Staphylococcus aureus biofilms. PLoS One, 9(3), 1-9.
Scopus44 WoS32 Europe PMC222014 Drilling, A., Morales, S., Boase, S., Jervis-Bardy, J., James, C., Jardeleza, C., . . . Wormald, P. (2014). Safety and efficacy of topical bacteriophage and ethylenediaminetetraacetic acid treatment of Staphylococcus aureus infection in a sheep model of sinusitis. International Forum of Allergy & Rhinology, 4(3), 176-186.
Scopus55 WoS49 Europe PMC392014 Paramasivan, S., Drilling, A., Jardeleza, C., Jervis-Bardy, J., Vreugde, S., & Wormald, P. (2014). Methylglyoxal-augmented manuka honey as a topical anti-Staphylococcus aureus biofilm agent: safety and efficacy in an in vivo model. International Forum of Allergy & Rhinology, 4(3), 187-195.
Scopus59 WoS46 Europe PMC362014 Goggin, R., Jardeleza, C., Wormald, P., & Vreugde, S. (2014). Colloidal silver: a novel treatment for Staphylococcus aureus biofilms?. International Forum of Allergy & Rhinology, 4(3), 171-175.
Scopus31 WoS26 Europe PMC192014 Goggin, R., Jardeleza, C., Wormald, P., & Vreugde, S. (2014). Corticosteroids directly reduce Staphylococcus aureus biofilm growth: an in vitro study. The Laryngoscope, 124(3), 602-607.
Scopus27 WoS21 Europe PMC202014 Tan, N., Cooksley, C., Paramasivan, S., Vreugde, S., & Wormald, P. (2014). Safety evaluation of a sinus surfactant in an explant-based cytotoxicity assay. The Laryngoscope, 124(2), 369-372.
Scopus8 WoS6 Europe PMC42013 Jardeleza, C., Miljkovic, D., Baker, L., Boase, S., Tan, N., Koblar, S., . . . Vreugde, S. (2013). Inflammasome gene expression alterations in Staphylococcus aureus biofilm-associated chronic rhinosinusitis. Rhinology, 51(4), 315-322.
Scopus12 WoS11 Europe PMC112013 Cantero Cajas, D., Cooksley, C., Bassiouni, A., Wormald, P., & Vreugde, S. (2013). Staphylococcus aureus biofilm activates the nucleotide-binding oligomerization domain containing 2 (Nod2) pathway and proinflammatory factors on a human sinonasal explant model. International Forum of Allergy & Rhinology, 3(11), 877-884.
Scopus13 WoS10 Europe PMC102013 Cantero Cajas, D., Cooksley, C., Jardeleza, C., Bassiouni, A., Jones, D., Wormald, P., & Vreugde, S. (2013). A human nasal explant model to study Staphylococcus aureus biofilm in vitro. International Forum of Allergy & Rhinology, 3(7), 556-562.
Scopus15 WoS14 Europe PMC142013 Tan, N., Foreman, A., Jardeleza, C., Douglas, R., Vreugde, S., & Wormald, P. (2013). Intracellular Staphylococcus aureus: the Trojan horse of recalcitrant chronic rhinosinusitis?. International Forum of Allergy & Rhinology, 3(4), 261-266.
Scopus58 WoS51 Europe PMC462013 Jardeleza, C., Jones, D., Baker, L., Miljkovic, D., Boase, S., Tan, N., . . . Wormald, P. (2013). Gene expression differences in nitric oxide and reactive oxygen species regulation point to an altered innate immune response in chronic rhinosinusitis. International Forum of Allergy & Rhinology, 3(3), 193-198.
Scopus16 WoS14 Europe PMC122013 Jardeleza, C., Miljkovic, D., Baker, L., Boase, S., Tan, N. C. W., Koblar, S. A., . . . Vreugde, S. (2013). Inflammasome gene expression alterations in Staphylococcus aureus biofilm-associated chronic rhinosinusitis. Rhinology journal, 51(4), 315-322.
2012 Tan, N. W., Tran, H., Foreman, A., Jardeleza, C., Vreugde, S., & Wormald, P. J. (2012). Identifying intracellular Staphylococcus aureus in chronic rhinosinusitis: A direct comparison of techniques. American Journal of Rhinology & Allergy, 26(6), 444-449.
Scopus17 WoS16 Europe PMC122012 Tan, N. W., Tran, H., Roscioli, E., Wormald, P. J., & Vreugde, S. (2012). Prevention of false positive binding during immunofluorescence of Staphylococcus aureus infected tissue biopsies. Journal of Immunological Methods, 384(1-2), 111-117.
Scopus8 WoS8 Europe PMC72006 Vreugde, S., Ferrai, C., Miluzio, A., Hauben, E., Marchisio, P., Crippa, M., . . . Biffo, S. (2006). Nuclear myosin VI enhances RNA polymerase II-dependent transcription. Molecular Cell, 23(5), 749-755.
Scopus118 WoS104 Europe PMC982006 Friedmann, E., Hauben, E., Maylandt, K., Schleeger, S., Vreugde, S., Lichtenthaler, S., . . . Martoglio, B. (2006). SPPL2a and SPPL2b promote intramembrane proteolysis of TNFalpha in activated dendritic cells to trigger IL-12 production. Nature Cell Biology, 8(8), 849-854.
2006 Friedmann, E., Hauben, E., Maylandt, K., Schleeger, S., Vreugde, S., Lichtenthaler, S. F., . . . Martoglio, B. (2006). SPPL2a and SPPL2b promote intramembrane proteolysis of TNFα in activated dendritic cells to trigger IL-12 production. Nature Cell Biology, 8(8), 843-848.
Scopus177 WoS161 Europe PMC1452002 Vreugde, S., Erven, A., Kros, C. J., Marcotti, W., Fuchs, H., Kurima, K., . . . Steel, K. P. (2002). Beethoven, a mouse model for dominant, progressive hearing loss DFNA36. Nature Genetics, 30(3), 257-258.
Scopus235 WoS200 Europe PMC2002002 Walsh, T., Walsh, V., Vreugde, S., Hertzano, R., Shahin, H., Haika, S., . . . Avraham, K. B. (2002). From flies' eyes to our ears: Mutations in a human class III myosin cause progressive nonsyndromic hearing loss DFNB30. Proceedings of the National Academy of Sciences of the United States of America, 99(11), 7518-7523.
Scopus200 WoS172 Europe PMC1602002 Adato, A., Vreugde, S., Joensuu, T., Avidan, N., Hamalainen, R., Belenkiy, O., . . . Lancet, D. (2002). USH3A transcripts encode clarin-1, a four-transmembrane-domain protein with a possible role in sensory synapses. European Journal of Human Genetics, 10(6), 339-350.
Scopus155 WoS128 Europe PMC1252000 Frydman, M., Vreugde, S., Nageris, B. I., Weiss, S., Vahava, O., & Avraham, K. B. (2000). Clinical characterization of genetic hearing loss caused by a mutation in the POU4F3 transcription factor. Archives of Otolaryngology Head and Neck Surgery, 126(5), 633-637.
Scopus26 WoS20 Europe PMC192000 Sobe, T., Vreugde, S., Shahin, H., Berlin, M., Davis, N., Kanaan, M., . . . Avraham, K. (2000). The prevalence and expression of inherited connexin 26 mutations associated with nonsyndromic hearing loss in the Israeli population. Human Genetics, 106(1), 50-57.
Scopus143 WoS123 Europe PMC1031999 Sobe, T., Erlich, P., Berry, A., Korostichevsky, M., Vreugde, S., Avraham, K. B., . . . Shohat, M. (1999). High frequency of the deafness-associated 167delT mutation in the connexin 26 (GJB2) gene in Israeli Ashkenazim [2]. American Journal of Medical Genetics, 86(5), 499-500.
Scopus59 WoS55 Europe PMC391999 Vreugde, S., Duttmann, R., Halama, A., & Deron, P. (1999). Metastasis of a renal cell carcinoma to the nose and paranasal sinuses. Acta Oto Rhino Laryngologica Belgica, 53(2), 129-131.
Scopus9 Europe PMC71997 De Maeseneer, M., Vreugde, S., Laureys, S., Sartoris, D. J., De Ridder, F., & Osteaux, M. (1997). Calcific tendinitis of the longus colli muscle. Head and Neck, 19(6), 545-548.
Scopus51 WoS37 Europe PMC271994 Vreugde, S. (1994). Nutritional aspects of dysphagia.. Acta Oto Rhino Laryngologica Belgica, 48(2), 229-234.
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Book Chapters
Year Citation 2023 Vreugde, S., & Wormald, P. J. (2023). The Current Concepts of Biofilms and Superantigens. In A. Swift, S. Carrie, & C. de Souza (Eds.), Contemporary Rhinology: Science and Practice (pp. 91-100). Springer International Publishing.
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Conference Items
Year Citation 2016 Lau, A. H. Y., Lester, S., Moraitis, S., Ou, J., Rischmueller, M., Wormald, P. J., & Vreugde, S. (2016). Tertiary Lymphoid Organ in Chronic Rhinosinusitis. Poster session presented at the meeting of 2016 ASMR South Australian Scientific Meeting. Convention Centre, Adelaide, South Australia, Australia. -
Preprint
Year Citation 2025 Awad, M., Bouras, G., Feizi, S., Grigson, S. R., Wormald, P. -J., Psaltis, A. J., & Vreugde, S. (2025). LicD-Mediated Cell Wall Decoration Governs Phage Sensitivity in Enterococcus faecalis Clinical Isolates.
DOI2024 Bouras, G., Judd, L., Edwards, R., Vreugde, S., Stinear, T., & Wick, R. (2024). How low can you go? Short-read polishing of Oxford Nanopore bacterial genome assemblies.
DOI Europe PMC32023 Bouras, G., Houtak, G., Wick, R., Mallawaarachchi, V., Roach, M., Papudeshi, B., . . . Vreugde, S. (2023). Hybracter: Enabling Scalable, Automated, Complete and Accurate Bacterial Genome Assemblies.
DOI2019 Parvaneh, A., Abbasnejad, E., Wu, Q., & Shi, J. (2019). Show, Price and Negotiate: A Hierarchical Attention Recurrent Visual Negotiator..
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Current Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2025 Principal Supervisor Exploring the Potential of Engineered Phages for Mycobacterium Abscessus Treatment: Innovating Precision Therapy Against Resistant Infections Doctor of Philosophy Doctorate Full Time Mr Muhammad Imran 2025 Co-Supervisor Engineering a Biocompatible Metal-Organic Framework (MOF) For Nasal Drug Delivery: Insights from Computational Fluid Dynamics (CFD) Models Doctor of Philosophy Doctorate Full Time Mr Nikzad Abbariki 2025 Co-Supervisor Core-Silica Coated Mesoporous Nanoparticles for Enhanced Drug Delivery in Chronic Rhinosinusitis Treatment Doctor of Philosophy Doctorate Full Time Mrs Sara Aghili 2024 Principal Supervisor Developing smart phage cocktails for difficult-to-treat infections Doctor of Philosophy Doctorate Full Time Mr Connor Jessop 2024 Principal Supervisor Unravelling the underlying mechanisms of chronic rhinosinusitis (CRS) pathogenesis and exploring the potential of bacteriophages as a therapeutic option Doctor of Philosophy Doctorate Full Time Mr Md Hasib Adnan 2024 Co-Supervisor A comprehensive Study of magnetic drug targeting in human maxillary sinuses for drug delivery applications Doctor of Philosophy Doctorate Full Time Mr Kavan Zarei 2024 Co-Supervisor A comprehensive numerical and experimental study of transport phenomena in nebulizer drug delivery targeting paranasal sinuses Doctor of Philosophy Doctorate Full Time Mr Alireza Meymivand 2024 Co-Supervisor Precision medicine in bacterial infections; exploring the use of personalised phage therapy and multi-omics technologies to improve the management of chronic rhinosinusitis Doctor of Philosophy Doctorate Full Time Miss Isabella Amy Burdon 2024 Co-Supervisor Bacteriophage therapy in CRS patient nasal wound healing Doctor of Philosophy Doctorate Full Time Mr Jordan Hall 2024 Principal Supervisor Maximising the antimicrobial and anti-inflammatory performance of next generation therapeutics for Chronic Rhinosinusitis Doctor of Philosophy Doctorate Full Time Mrs Marzieh Eskandarzadeh 2023 Co-Supervisor Target the tumour microbiome to improve head & neck cancer treatment outcomes Doctor of Philosophy Doctorate Full Time Mrs Lee Mai 2023 Principal Supervisor Exploring The Efficacy Of Bacteriophage Therapy In Disrupting Poly-Microbial Biofilms In Chronic Rhinosinusitis Doctor of Philosophy Doctorate Full Time Mr Xiaohan Sun 2023 Principal Supervisor Potential use of essential oils from ethno-medicinal plants in clinical research Doctor of Philosophy Doctorate Full Time Miss Sumeena Karki 2023 Principal Supervisor Investigating Phage, Microbe and Host Interactions by Integrating Systems Multiomics Doctor of Philosophy Doctorate Full Time Mr George Spyro Bouras 2023 Principal Supervisor Studying the Potential of Bacteriophage Loaded Chitosan-Silk Hydrogel as a Novel Formulation for Chronically Infected Wounds Doctor of Philosophy Doctorate Full Time Ms Zahra Aliakbar Ahovan 2022 Principal Supervisor The role of various Staphylococcus species in eliciting inflammation in Chronic rhinosinusitis Doctor of Philosophy Doctorate Full Time Mr Sintayehu Ambachew Wondemagegn -
Past Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2023 - 2024 Co-Supervisor The Microbiome of Allergic Fungal Rhinosinusitis Doctor of Philosophy Doctorate Full Time Dr James Thomas Connell 2023 - 2024 Co-Supervisor Repurposing Mesalazine as a Potential Treatment Option for Chronic Rhinosinusitis Doctor of Philosophy Doctorate Full Time Mr William Mark Murphy 2021 - 2024 Principal Supervisor Characterising the Microbiome and its Diagnostic and Prognostic Value in Head and Neck Cancer Doctor of Philosophy Doctorate Full Time Mr Kenny Ker Li Yeo 2021 - 2025 Co-Supervisor Development of An Animal Model of Endoscopic Small-Vessel Haemorrhage Control, Brain Manipulation and Dural Closure Doctor of Philosophy Doctorate Full Time Dr Annika Reann Mascarenhas 2021 - 2023 Co-Supervisor Investigating Transcription Factors in the Human Airway Mucosal Immunoepigenetics of Chronic Inflammatory Disease Master of Philosophy (Surgery) Master Full Time Mr Harrison Burchill Bolt 2020 - 2022 Co-Supervisor The Relationship Between S. Aureus Biofilm Properties, Inflammation, and Disease Severity in Chronic Rhinosinusitis Doctor of Philosophy Doctorate Full Time Mrs Gohar Shaghayegh 2020 - 2023 Co-Supervisor Topical Therapies for The Management of Recalcitrant Chronic Rhinosinusitis Doctor of Philosophy Doctorate Full Time Dr Anna Katharina Megow 2019 - 2023 Principal Supervisor The Adaption and Inflammation-Inducing Capacity of Staphylococcus Aureus in Chronic Rhinosinusitis Doctor of Philosophy Doctorate Full Time Mr Ghais Houtak 2019 - 2023 Principal Supervisor Role of Prophages in Staphylococcus aureus Virulence and Pathogenicity Doctor of Philosophy Doctorate Full Time Mr Roshan Nepal 2018 - 2020 Principal Supervisor The Host-Microbe Interface in Chronic Rhinosinusitis Doctor of Philosophy Doctorate Full Time Mr Sathish Paramasivan 2018 - 2021 Co-Supervisor Modifying Post-Surgical Wound Healing Doctor of Philosophy Doctorate Full Time Rajan Vediappan 2018 - 2020 Principal Supervisor The role of viruses in chronic rhinosinusitis Doctor of Philosophy Doctorate Full Time Dr Rachel Katherine Goggin 2018 - 2022 Principal Supervisor The Role of Colloidal Silver Synthesized from Corymbia Maculata in Eradicating Infection in Chronic Rhinosinusitis Doctor of Philosophy Doctorate Full Time Miss Sholeh Feizi 2018 - 2022 Principal Supervisor Investigating Microbiome - Targeted Treatments for Chronic Rhinosinusitis: A novel approach to combat dysbiosis in the nasal microbiome Doctor of Philosophy Doctorate Full Time Mrs Martha Menberu 2017 - 2020 Co-Supervisor Staphylococcus aureus Exoproteins on Nasal Epithelial Barrier in Chronic Rhinosinusitis Doctor of Philosophy Doctorate Full Time Dr Beula Subashini Panchatcharam 2017 - 2020 Co-Supervisor Bacteriophage Therapy for Chronic Rhinosinusitis: Targeting Pseudomonas Aeruginosa Biofilms Doctor of Philosophy Doctorate Full Time Miss Stephanie Anne Fong 2017 - 2020 Co-Supervisor Novel Topical Anti-biofilm Agents in the Treatment of Recalcitrant Chronic Rhinosinusitis Doctor of Philosophy Doctorate Full Time Miss Mian Li Ooi 2016 - 2019 Co-Supervisor Corticosteroids and the Sinonasal Microbiome Doctor of Philosophy Doctorate Full Time Dr Lisa Mary Cherian 2016 - 2017 Co-Supervisor The microbiome of otitis media with effusion and the influence of Alloicoccus otitidis on Haemophilus influenzae in polymicrobial biofilm Doctor of Philosophy Doctorate Full Time Dr Chun Chan 2015 - 2018 Principal Supervisor An Immunological Perspective of the Mucosal Inflammation in Chronic Rhinosinusitis – Lymphoid Neo-organogenesis and Humoral Immunity Doctor of Philosophy Doctorate Full Time Mr Aden Lau 2015 - 2018 Co-Supervisor The Mucosal Barrier in Chronic Rhinosinusitis Doctor of Philosophy Doctorate Full Time Mr Jae Viktor Murphy 2014 - 2017 Co-Supervisor The Role of Immune Cells in Chronic Rhinosinusitis Doctor of Philosophy Doctorate Full Time Ms Dijana Miljkovic 2014 - 2017 Principal Supervisor Towards Novel Antibiofilm Strategies Doctor of Philosophy Doctorate Full Time APrf Katharina Richter 2013 - 2015 Co-Supervisor Management of Major Vessel Haemorrhage in Endonasal Surgery Doctor of Philosophy Doctorate Full Time Vikram Padhye 2012 - 2014 Co-Supervisor Nitric Oxide and Staphylococcus aureus Biofilms: Defining their Intricate Relationship in Chronic Rhinosinusitis Doctor of Philosophy Doctorate Part Time Dr Camille Jardeleza 2012 - 2014 Co-Supervisor The innate immune response to Staphylococcus aureus biofilms on human sinonasal explants Doctor of Philosophy Doctorate Full Time Mr Daniel Anibal Cantero Cajas 2012 - 2013 Co-Supervisor Intracellular Staphylococcus aureus in chronic rhinosinusitis Doctor of Philosophy Doctorate Full Time Dr Neil Cheng-Wen Tan 2012 - 2015 Co-Supervisor The Role of Surgery and Disease Load in Refractory Chronic Rhinosinusitis Doctor of Philosophy Doctorate Full Time Mr Ahmed Bassiouni 2012 - 2015 Co-Supervisor The Effect of Chitosan Dextran Gel as a Haemostatic and Anti Adhesion Agent in the Central Nervous System and Evaluation of Haemostatic Mechanism of Skeletal Muscle Tissue Doctor of Philosophy Doctorate Full Time Dr Sukanya Rajiv 2012 - 2014 Co-Supervisor The Chronic Rhinosinusitis Microbiome Doctor of Philosophy Doctorate Full Time Dr Edward John Cleland
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Committee Memberships
Date Role Committee Institution Country 2019 - ongoing Chair BHI Strategic Research Directions Committee Basil Hetzel Institute Australia 2016 - ongoing Member TQEH Human Research Ethics Committee - - 2014 - ongoing Member The Basil Hetzel Institute Management Committee The Bsil Hetzel Institute Australia 2011 - ongoing Chair Selection committee for scientist positions - - -
Memberships
Date Role Membership Country 2017 - ongoing Member American Society of Microbiology - -
Editorial Boards
Date Role Editorial Board Name Institution Country 2018 - ongoing Associate Editor Frontiers in Cellular and Infection Microbiology Frontiers Journals United Kingdom 2016 - ongoing Associate Editor Sinusitis - -
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