Adelaide Medical School
Faculty of Health and Medical Sciences
Eligible to supervise Masters and PhD - email supervisor to discuss availability.
Dr Sarah Bray - TITLEHOLDER.
Project Manager, Registry Of Older South Australians (ROSA).
I have a wide interest in science, health and fitness and am also passionate about science engagement with the wider community. I have worked on a diverse range of projects over my career so far, from medical research projects in cancer biology (leukaemia and rare blood disorders) and tropical infectious disease research for a biotech company, to my PhD project wrangling ancient DNA from extinct bears! My background and experience in working in such a diverse range of research areas as a scientist and research admin/manager has given me the ability to understand and interpret complex scientific and medical information, and to communicate the research in meaningful ways to different audiences.
In my current role at SAHMRI, I helped establish & develop the Registry of Older South Australians (ROSA), including managing the complex ethics and governance requirements for this ambitious resource that seeks to improve the lives of all Australians accessing aged care services. I also coordinate the consumer & community engagement activities for ROSA.
ROSA was established in 2017 by the Healthy Ageing Research Consortium – a cross-sectoral partnership of researchers, clinicians, aged care providers and consumer advocacy groups. ROSA is designed to monitor the health, service utilisation, medication use, mortality, and other outcomes of people receiving aged care services in South Australia. ROSA’s efficient model leverages existing information from both the aged care and health care sectors, bringing together diverse datasets already collected by different organisations throughout the country, to provide us with a more complete picture of the ageing pathway.
In my current role at SAHMRI, I am the Project Manager + Consumer Engagement Officer for the Registry of Older South Australians (ROSA). ROSA was established in 2017 and is a resource that allows evidence-driven decision-making to improve the lives of all Australians accessing aged care services. ROSA’s model leverages existing information from both the aged care and health care sectors, bringing together diverse datasets collected by different organisations throughout the country, to provide us with a more complete picture of the ageing pathway. Like other Australian Clinical Quality Registries, ROSA was designed to monitor the effectiveness and appropriateness of care over time, to identify variance and advise on best practices.
Some of the research the ROSA team have undertaken recently include providing evidence on:
1) the effect of wait time for home care services on the health of older Australians,
2) the prevalence of dementia in the aged care population in Australia and its effect on mortality, and
3) the increasing pervasiveness of pain reported in this population.
For more information on ROSA, please check out our website: www.rosaresearch.org
For information on potential student projects (Honours, Masters, PhD) with the ROSA Research Team, please visit the Student Projects section of our website: https://rosaresearch.org/studentprojects
Date Position Institution name 2017 Project Manager SAHMRI 2014 - 2015 Postdoctoral Fellow - Acute Leukaemia Lab University of South Australia 2014 - 2015 Affiliate Lecturer University of Adelaide 2010 - 2013 Postdoctoral Fellow (2011-2014), Research Assistant (2010-2011) - Acute Leukaemia Lab - Basil Hetzel Institute TQEH University of Adelaide 2004 - 2006 Production Scientist Cellabs Pty Ltd 2004 - 2006 R&D Scientist Special Phage Services
Date Institution name Country Title — Univesity of Adelaide Australia PhD (Science) — University of New South Wales Australia BSc (hons) Molecular Biology
Year Citation 2016 Bassal, M. A., Leo, P., Samaraweera, S. E., Maung, K. Z. Y., Babic, M., Venugopal, P., . . . D'Andrea, R. (2016). Metabolic Profiling of Adult Acute Myeloid Leukemia (AML). In BLOOD Vol. 128 (pp. 6 pages). San Diego, CA: AMER SOC HEMATOLOGY. 2016 Maung, K. Z. Y., Leo, P., Brown, A. L., Bassal, M. A., Casolari, D. A., Ewing, A., . . . D'Andrea, R. (2016). Rare Variants Affecting the Fanconi Anaemia DNA Repair Genes Associate with Increased Risk for AML. In BLOOD Vol. 128 (pp. 5 pages). San Diego, CA: AMER SOC HEMATOLOGY. 2016 Samaraweera, S. E., Garrett-Bakelman, F. E., Neelamraju, Y., Perugini, M., Casolari, D. A., Iarossi, D., . . . D'Andrea, R. (2016). Hypermethylation of GADD45A Defines a Methylation Profile Distinct to Mutant IDH1/2, and Correlates with More Aggressive AML. In BLOOD Vol. 128 (pp. 6 pages). San Diego, CA: AMER SOC HEMATOLOGY. 2015 Li, K. L., Bray, S. C., Iarossi, D., Adams, J., Zhong, L., Noll, B., . . . D'Andrea, R. J. (2015). Investigation of a Novel Cyclin-Dependent-Kinase (CDK) Inhibitor Cdki-73 As an Effective Treatment Option for MLL-AML. In BLOOD Vol. 126 (pp. 3 pages). Orlando, FL: AMER SOC HEMATOLOGY.
2014 Casolari, D. A., Iarossi, D. G., Butcher, C. M., Bray, S. C., Parker, W. T., Hahn, C. N., . . . D'Andrea, R. J. (2014). Aberrant Activation of Epidermal Growth Factor Receptor in MPN May Respond to the Kinase Inhibitor Gefitinib. In BLOOD Vol. 124 (pp. 3 pages). San Francisco, CA: AMER SOC HEMATOLOGY. 2011 Rao, N., Butcher, C., Neufing, P., Bray, S., Hahn, C., Scott, H., . . . D'Andrea, R. (2011). Mechanisms of Co-operation of DNMT3A Mutations with JAK2 V617F Through Histone H4 Arginine 3 Provides New Insights in MPN Disease Pathogenesis. In 53rd ASH Annual Meeting and Exposition Vol. 118 (pp. 1). Washington DC: AMER SOC HEMATOLOGY. 2007 Austin, J., Bray, S., Worthy, T., & Medlin, G. (2007). Reconstructing Southern Hemisphere late-Pleistocene and Holocene paleaeo-environments using ancient DNA from cave and swamp-preserved bones and sediments. In N. R. Catto (Ed.), Quarternary International: The journal of the International Union for Quaternary Research (pp. 19). United Kingdom: Pergamon.
Year Citation 2014 Maung, K. Z., Gray, J. X., Leo, P. J., Bassal, M., Brown, A. L., Bray, S. C., . . . Gonda, T. J. (2014). Whole Exome Sequencing of Acute Myeloid Leukaemia Patients Identifies Somatic and Germline Mutations in Fanconi Anaemia Genes. Poster session presented at the meeting of BLOOD. San Francisco, CA: AMER SOC HEMATOLOGY. 2012 Bray, S. C., Wee, A., Perugini, M., To, L. B., & D'Andrea, R. J. (2012). Expression of Erythroid Transcription Factors Are Decreased in a RPS19 Knockdown Cell Line Model of Diamond Blackfan Anaemia. Poster session presented at the meeting of BLOOD. Atlanta, GA: AMER SOC HEMATOLOGY. 2007 Bray, S., Austin, J., Barnes, I., Weinstock, J., Shapiro, B., & Cooper, A. (2007). The evolution and genetic diversity of the extinct Tremarctine bears.. Poster session presented at the meeting of Conference on Australasian Vertebrate Evolution Palaeontology and Systematics. Melbourne, Vic: Geological Society of Australia.
Year Citation 2011 Bray, S. C. (2011). Mitochondrial DNA Analysis of the Evolution and Genetic Diversity of Ancient and Extinct Bears. (PhD Thesis).
ROSA was established in 2017 by the Healthy Ageing Research Consortium, a partnership of researchers, clinicians, aged care providers and consumer advocacy groups. The consortium is supported by the South Australian Government through the Department for Innovation and Skills, and coordinated under the auspices of the SA Academic Health Science and Translation Centre. The Consortium’s 13 collaborating organisations are: South Australian Health and Medical Research Institute (SAHMRI), 3 universities (University of Adelaide, University of South Australia, and Flinders University), 5 industry partners (Helping Hand, Silver Chain, ECH, Adelaide PHN, Country SA PHN), 2 consumer health advocacy groups (COTA SA, HCA SA), SA NT DataLink, and SA Health.
The Healthy Ageing Research Consortium is supported by the South Australian Government through the Department for Innovation and Skills.
Past Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2013 - 2017 Co-Supervisor Investigating Rare Pathogenic Mutations of the Extended Fanconi Anaemia DNA Repair Pathway in Acute Myeloid Leukaemia (AML) Doctor of Philosophy Doctorate Full Time Mr Kyaw Ze Ya Maung
Other Supervision Activities
Date Role Research Topic Location Program Supervision Type Student Load Student Name 2014 - 2018 Co-Supervisor Investigation of the mode of action of a novel multi-kinase inhibitor, CDKI-73, and its potential as a therapeutic treatment for Acute Myeloid Leukaemia (AML) University of South Australia Doctor of Philosophy Doctorate Full Time Ka Leung (Nick) Li 2013 - 2013 Co-Supervisor Diamond Blackfan Anemia University of Adelaide Masters of Biotechnology Master Full Time Puspita Suci Wulandari
Date Role Committee Institution Country 2019 - 2019 Member SAHMRI Reconciliation Week Event - Working Group SAHMRI Australia 2018 - ongoing Member Health Translation SA Consumer & Community Engagement Action Group Health Translation SA Australia 2018 - 2019 Member Theo Murphy Initiative (Australia) - Frontiers of Science Organising Committee SAHMRI Australia 2018 - ongoing Co-Chair ROSA Consumer & Community Committee SAHMRI Australia 2016 - ongoing Member Inspiring South Australia - Working Group Inspiring SA Australia
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