Professor Sandra Hodge

Head Chronic Lung Disease Research Lab

Adelaide Medical School

Faculty of Health and Medical Sciences

Eligible to supervise Masters and PhD - email supervisor to discuss availability.

I am Head of the Chronic Inflammatory Lung Disease Research Lab at the Royal Adelaide Hospital and this year joined the University of Adelaide as a Beacon Professorial Research Fellow at the new Adelaide Health and Medical Sciences (AHMS) building. My team's research focus is the identification and therapeutic targeting of failed clearance of apoptotic cells and bacteria in the airway, and its pro-inflammatory consequences, in severe, treatment refractory chronic lung diseases including COPD/emphysema, neutrophilic asthma, childhood bronchiectasis and chronic lung transplant rejection.
We have extensively published our work (eg, Prof Hodge 127 refereed manuscripts and over 200 conference papers) and have secured $16 million in research funding.

My Research
Career
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Professional Activities
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Chronic Inflammatory Lung Disease Research Lab

Our Team

We are part of the Lung Research Unit, at the Department of Thoracic Medicine at the Royal Adelaide Hospital and The University of Adelaide. Our research program largely focusses on macrophage-targeted therapeutic approaches for severe chronic lung diseases that are resistant to current therapies.

Funded collaborative projects include those in (COPD/emphysema), lung transplant rejection, steroid-resistant asthma and bronchiectasis in Indigenous children. Our multi-discipline and internationally recognised team was the first to describe failed clearance of apoptotic cells by airway macrophages (efferocytosis) in COPD that underlies the chronic inflammation and tissue damage and is not resolved with cessation of cigarette smoking once the disease is established.

We have already shown, in human clinical studies and/or murine models that several macrophage-targeted therapies including macrolide antibiotics have properties that restore airway function in this context, beyond combatting microbial infection. In a recent large randomised controlled clinical trial of the macrolide antibiotic Azithromycin (published in Thorax 2017) we and our national collaborators identified Azithromycin as a useful add-on therapy in persistent severe symptomatic asthma. However, bacterial resistance following long-term macrolide treatment necessitates new approaches, and we are now investigating new macrolides, which lack antibiotic but retain anti-inflammatory properties (in collaboration with Gilead Sciences, USA). We have recently published exciting proof-of-concept findings in the Am J Physiol.

**Sandra HODGE, MSc, PhD, FThorSoc*: Brief Track Record***

I am a Beacon Professorial Research Fellow at the University of Adelaide and Head of the Chronic Inflammatory Lung Disease Research Lab at the Royal Adelaide Hospital and University of Adelaide. Three early papers on which I was first author are considered seminal and I am recognised internationally as the first to describe a failed capacity of airway macrophages to phagocytose apoptotic bronchial epithelial cells and bacteria and its pro-inflammatory consequences in severe, treatment refractory chronic lung diseases including COPD/emphysema, asthma, lung cancer, childhood BE and lung transplantation, and identification and translation of macrophage-targeted therapies to clinical trial. I have published 130 refereed manuscripts (74% first or senior author) and ~200 conference papers. 4457 cites, H36 (Google Scholar) and received 17 awards and 15 international invitations as speaker (8 plenary/keynote) or chair (27)), with national and 7 international teams (4 with industry- Astra Zeneca, Boehringer, BD and Gilead) and invitations to Drug Discovery meetings and position paper writing groups. I am an elected Board Director of TSANZ, Chair of the Research Sub-committee and a Fellow of the TSANZ.

Top manuscripts last 10yrs: All below are Q1 rated and in top 10 journals in field.

1. Landmark RCT (AMAZES) showing Azithromycin reduces asthma exacerbations by >30% over 1yr. Incorporated into latest GINA severe asthma guidelines with major implications for changes in practice. Lancet 2017, FWCI 28, PMID28687413, highly cited Q1 paper

2. New knowledge of mechanisms for colonisation of potentially pathogenic bacteria and its severe clinical manifestations in COPD, and a rationale for use of long-term Azithromycin to reduce colonisation and prevent exacerbations, Respirology 2012 PMID22288725, Featured in MDLinx and Lung Disease News, Editorial focus (Hansbro and Jarnicki), FWCI 39, in the top 25% of all research outputs scored by Altmetric Media.

3. Pioneering study with Gilead US showed that new non anti-microbial macrolides are anti-inflammatory and improve macrophage function. This approach provides an alternative to macrolides thus addresses significant concerns about anti-microbial resistance. A resultant change in drug development focus by the pharmaceutical company has progressed to pre-clinical murine studies. Am J Physiol 2017 PMID28258107

4. One of several cigarette smoke-exposed murine studies showing anti-inflammatory effects of new macrophage-targeted therapies provided mechanistic knowledge and advised a great deal of subsequent research by us and others (eg, macrolides). Am J Respir Cell Mol Biol 2011, PMID20595463 Faculty 1000 selected, FWCI 4.31

5. One of 5 from 5yr prospective cohort study that identified potential development of bronchiectasis in children with PBB, a common cause of childhood chronic cough. Incorporated into ERS taskforce paper and reviews, informing future therapy and the need for better clinical follow up of children with PBB. Chest 2016 PMID26867834.

Grants and awards: My salary, and those of my team have been 100% funded by competitive grants (>$13 million as CI), including grants from NHMRC (9 as CI), specialist agencies (Asthma Australia, ARC, Cancer Council, CellCept, TSANZ/Allan Hanbury’s, TSANZ Robert Pierce GIA for Indigenous Lung Health, ALF/Boehringer Ingelheim, Ch7 CRE, Brine Bequest, and state competitive schemes. I was awarded the Hanson Institute Early Career Researcher of the Year and the prestigious University of Adelaide Beacon Research Fellowship.

Peer Recognition: National standing is evident by appointment to NHMRC GRPs (2012-2019); GRP Co-Chair (2013), Deputy Convenor (2013-2014) and Convenor (2015-2016) of TSANZ Cell Biology and Immunology SIG, member TSANZ Education and Research Sub-committee (2012-16), Co-chair Research Sub-committee (2017-2018) and Chair (current) and invitations to chair numerous oral sessions including the Ann Woolcock YIA over several years. In 2012 I was awarded a TSANZ Silver Pin for service to the Society and this year appointed as a Fellow of the Society. I am elected TSANZ Board Director and have served as Treasurer and member Finance and Risk Assessment Committee. I was National President of the AFCG, represented NHMRC at Science Meets Parliament, invited to the TEVA Respiratory Summit, and Australian Mucosal Immunology Group. I am current member of Registries and Clinical Trials sub-committee; Rebecca Cooper Scientific Advisory Committee; RAH Clinical Project Grant, RIBG and Research Equipment Advisory committees. I am a member and have been involved as conference organiser, speaker and Chair for 8 international societies including ATS, ISHLT, APSR/ACCP, AFCG/ASI/HLDA and numerous national societies.

Reviewing roles: 15 international; >30 national bodies/yr; NHMRC GRP 2012-19; PhD examiner 5 Aust Universities; 43 journals eg Lancet, NEJM, all top respiratory journals, invited guest-editor 5 special issues, Chief Book Editor, Editorial Board Member 3 scientific journals (currently Inflammation Research); Chair TSANZ Research Committee- objective to advise the Board on strategies for supporting research amongst members, and providing unbiased adjudication of >$1mill/year in awards.

Community: 4 clinical trials, impacting clinical practice; career advisory forums for 2ndry students as a founding member of Zonta Club; work experience for ~4/year 2ndry and 3^rd year Biomedical Science students; represented NHMRC at ‘Science Meets Parliament’ raising awareness of COPD among parliamentarians; media releases (24 since 2012) and feature in ‘The Limbic’, Spanish ‘Muy Interesante’ and Boehringer booklet ‘Where are they now?’ as one of 12 top Australian researchers in my field raised community awareness of my research.

Membership of major health policy advisory groups and translation into policy / practice

As TSANZ Board Director contributed to five position papers, three guidelines; two current position paper writing groups and submission to 2018 Federal Government Inquiry into E-cigarettes; consulted by Government as witness for the 2017 SA Government Select Inquiry into E-cigarettes (resultant changes to legislation); contributed to 2012 Lung Health Alliance Submission for Strategic Review of Health and Medical Research; invited Pharmaceutical Company Advisor (GlaxoSmithKline R&D 2006; AstraZeneca R&D Sweden 2015). Clinical trial involvement including two with azithromycin in COPD and asthma advised better-informed use of add-on macrolide therapies in chronic lung diseases and likely incorporation into International clinical guidelines. With Gilead USA our current investigations of non-antimicrobial macrolides are addressing the global priority of halting the generation of further antibiotic resistant bacteria.

International collaborations/ interactions with pharmaceuticals companies: My expertise and models of COPD and other chronic inflammatory lung are now internationally sought after and several of our discoveries have been the subject of national electronic and print media news. Collaborations include Aust. Red Cross Blood Service, AstraZeneca R&D, Advisor (2011-2012), GlaxoSmithkline (USA) COPD Drug Discovery group; (2008), Universities of Duisburg-Essen Germany, Tabuk, Saudi Arabia and Gothenburg Sweden, National Research Institute on Food & Nutrition Italy, Imperial College London, Gilead Sciences USA and Universitätsmedizin Berlin.

Selected invitations to speak at major international conferences (*fully funded):

2019 Combined Respiratory Society of Vietnam and University of Medical Sciences, Ho Chi Minh City (Symposium Plenary speaker)*.
2018 Le Centre Hospitalier Universitaire Vaudois Switzerland (Invited speaker).
2018 Asthma and Respiratory Foundation New Zealand (Plenary 1. Keynote speaker)*.
2018 Asthma and Respiratory Foundation New Zealand (Plenary 2. Panel member)*.
2015 Amgen USA (Invited speaker).
2014 Université de Lausanne, Switzerland (Symposium Plenary speaker).
2013 Le Centre Hospitalier Universitaire Vaudois Switzerland (Plenary speaker).
2011 Int Lectin Society (Symposium keynote speaker) *.
2010 American Thoracic Society (ATS) (Symposium keynote speaker*).
2009 National Jewish Medical Research, Denver, USA* (Visiting Professor and plenary speaker).
2009 University of Denver, USA* (Symposium Plenary speaker).
2008 GlaxoSmithkline (USA) COPD Drug Discovery group* (Panel member).
2010 ATS New Orleans 2010 Oral Cell Biology Session, (Panel member).
2007 12th Congress of APSR/2nd Joint Congress of the APSR/ACCP, Australia (Invited speaker).
2004 Federation of Immunological Societies of Asia-Oceania (FIMSA) (Workshop facilitator).

Current research programs include:

Macrophage targeted therapies for chronic lung diseases
Adaptive and innate immunity in Indigenous children with bronchiectasis
Autophagy and its links to apoptosis and zinc homeostasis in chronic lung disease
The effects of E-cigarettes on airway health
Inflammasome activation in chronic lung disease
Zinc regulation in the microvasculature

Research funding acknowledgements

The National Health and Medical Research Council, Thoracic Society of Australia and New Zealand, Lung Foundation Australia, Royal Adelaide Hospital, Channel 7 Children’s Research Foundation and the University of Adelaide.

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Appointments

Date Position Institution name
2017 - 2019 Professorial Research Fellow The University of Adelaide
2010 Head Chronic Inflammatory Lung Disease Research Lab Royal Adelaide Hospital, Adelaide

Date	Position	Institution name
2017 - 2019	Professorial Research Fellow	The University of Adelaide
2010	Head Chronic Inflammatory Lung Disease Research Lab	Royal Adelaide Hospital, Adelaide

Awards and Achievements

Date	Type	Title	Institution Name	Country	Amount
2018	Distinction	Treasurer, Thoracic Society of Australia and New Zealand	Treasurer, Thoracic Society of Australia and New Zealand	Australia	—
2018	Invitation	Writing Group Member: TSANZ Position Paper: Electronic Nicotine (and non-nicotine) Delivery Systems	TSANZ Position Paper: Electronic Nicotine (and non-nicotine) Delivery Systems	Australia	—
2018	Invitation	Writing Group Member: TSANZ Position Paper Alpha-1 Antitrypsin deficiency writing group	TSANZ	Australia	—
2018	Nomination	NHMRC Grant Review Panel	NHMRC	Australia	—
2018	Invitation	Chair and Judge, Anne Woolcock New Investigator Award	Thoracic Society of Australia and New Zealand	Australia	—
2017	Award	International Travel Award	TSANZ/Menarini	Australia	3,000
2017	Invitation	Grand Round Presentation	Royal Adelaide Hospital	Australia	—
2017	Invitation	Keynote speaker	Thoracic Society of Australia and New Zealand	Australia	—
2017	Award	COPD Research Award	Boehringer Ingelheim/ TSANZ	Australia	—
2017	Award	University Professorial Research Fellow (E)	The University of Adelaide	Australia	—
2017	Distinction	Co-Chair Research Sub-Committee	Thoracic Society of Australia and New Zealand	Australia	—
2017	Invitation	Invoited Chair, International Meeting	Asia Pacific Society for Respirology	Australia	—
2017	Award	International Research Travel Award	Lung Foundation Australia/ A. Menarini Australia	Australia	—
2017	Invitation	Invited presenter, SA Government Select Enquiry into E-cigarettes	SA Government	Australia	—
2017	Invitation	Judge, TSANZ 50th Anniversary Benevolent Grant	Thoracic Society of Australia and New Zealand	Australia	—
2017	Invitation	Invited Grand Round Presenter, Royal Adelaide Hospital	Royal Adelaide Hospital	Australia	—
2017	Invitation	Contributer, TSANZ submission to Australian Government Inquiry into the Use and Marketing of Electronic Cigarettes and Personal Vaporisers in Australia	Australian Federal Government	Australia	—
2016	Award	TSANZ/Robert Pierce Award for Indigenous Lung Health Research	—	—	—
2014	Achievement	Expert Guide Australia: Expert in Medicine/ Medical Research Category Asthma	—	—	—
2013	Award	TSANZ/Robert Pierce Award for Indigenous Lung Health Research	—	—	—
2012	Award	TSANZ Award of Silver Pin for service to the Society	—	—	—

Education

Date	Institution name	Country	Title
—	The University of Adelaide	Australia	PhD
—	University of South Australia	Australia	MSc
—	University of South Australia	Australia	Diploma in Applied and Visual Art
—	University of South Australia	Australia	Diploma in Biomedical Science

Research Interests

Cellular Immunology Clinical Sciences Respiratory System Cardiac, Respiratory and Vascular Health Immunology and Infection Indigenous and Disadvantaged Health Innovative Therapeutics

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Journals

Year	Citation
2019	Fricker, M., Gibson, P., Powell, H., Simpson, J., Yang, I., Upham, J., . . . Baines, K. (2019). A sputum 6-gene signature predicts future exacerbations of poorly controlled asthma. Journal of Allergy and Clinical Immunology. DOI
2019	Hodge, G., & Hodge, S. (2019). Therapeutic targeting steroid resistant pro-inflammatory NK and NKT-like cells in chronic inflammatory lung disease. International Journal of Molecular Sciences, 20(6). DOI
2019	Marsh, R., Smith-Vaughan, H., Chen, A., Marchant, J., Yerkovich, S., Gibson, P., . . . Chang, A. (2019). Multiple Respiratory Microbiota Profiles Are Associated With Lower Airway Inflammation in Children With Protracted Bacterial Bronchitis. Chest, 155(4), 778-786. DOI
2019	Hodge, G., Hodge, S., Yeo, A., Nguyen, P., Hopkins, E., Liu, H., . . . Holmes, M. (2019). BOS is associated with decreased HDAC2 from steroid resistant lymphocytes in the small airways. Clinical and Experimental Immunology, 195(2), 277-285. DOI Scopus1 Europe PMC1
2019	Hodge, G., & Hodge, S. J. (2019). Functional changes in steroid resistant NK and NKT-like cells in chronic inflammatory lung disease.. International Journal of Molecular Sciences.
2019	Hodge, S. J., & Hodge, G. (2019). BOS is associated with decreased SIRT1 in peripheral blood pro-inflammatory T, NK and NKT-like lymphocytes. Transplantation.
2018	Hamon, R., Tran, H., Roscioli, E., Ween, M., Jersmann, H., & Hodge, S. (2018). Bushfire smoke is pro-inflammatory and suppresses macrophage phagocytic function. Scientific Reports, 8(1), 13424-1-13424-11. DOI WoS1
2018	Roscioli, E., Hamon, R., Lester, S., Jersmann, H., Reynolds, P., & Hodge, S. (2018). Airway epithelial cells exposed to wildfire smoke extract exhibit dysregulated autophagy and barrier dysfunction consistent with COPD. Respiratory Research, 19(1), 234-1-234-13. DOI
2018	Taylor, S., Leong, L., Choo, J., Wesselingh, S., Yang, I., Upham, J., . . . Rogers, G. (2018). Inflammatory phenotypes in patients with severe asthma are associated with distinct airway microbiology. Journal of Allergy and Clinical Immunology, 141(1), 94-103e.15. DOI Scopus27 WoS22 Europe PMC15
2018	Hodge, G., Hodge, S., Nguyen, P., Yeo, A., Sarkar, P., Badiei, A., . . . Holmes, M. (2018). Bronchiolitis obliterans syndrome is associated with increased p-glycoprotein expression and loss of glucocorticoid receptor from steroid-resistant proinflammatory CD8⁺ T cells. Clinical and Experimental Immunology, 192(2), 242-250. DOI Scopus1 Europe PMC1
2018	Chen A, Pena O, Nel H, Yerkovich S, Petsky H, Pizzutto S, Baines K, Peter G. Gibson, Hodge S, Masters I, Buntain H, Chang A, Upham J.. (2018). Airway cells from protracted bacterial bronchitis and bronchiectasis share similar gene expression profiles.. Pediatric Pulmonology, 53(5), 1-8. DOI Scopus5
2018	Chen, A. C. -H., Tran, H. B., Xi, Y., Yerkovich, S. T., Baines, K. J., Pizzutto, S. J., . . . Upham, J. W. (2018). Multiple inflammasomes may regulate the interleukin-1-driven inflammation in protracted bacterial bronchitis. ERJ Open Research, 4(1), 00130-2017-1-00130-2017-11. DOI
2017	Chen AC, Xi Y, Carroll M, Petsky HL, Gardiner SJ, Pizzutto SJ, Yerkovich ST, Baines KJ, Gibson PG, Hodge S, Masters IB, Buntain HM, Chang AB, Upham JW.. (2017). Cytokine responses to two common respiratory pathogens in children are dependent on interleukin-1β. ERJ Open Research, 3(4), 1-10. DOI
2017	Roscioli, E., Jersmann, H., Lester, S., Badiei, A., Fon, A., Zalewski, P., & Hodge, S. (2017). Zinc deficiency as a codeterminant for airway epithelial barrier dysfunction in an ex vivo model of COPD. International Journal of Chronic Obstructive Pulmonary Disease, 12, 3503-3510. DOI Scopus1 WoS1 Europe PMC1
2017	Roscioli, E., Tran, H., Jersmann, H., Nguyen, P., Hopkins, E., Lester, S., . . . Hodge, S. (2017). The uncoupling of autophagy and zinc homeostasis in airway epithelial cells as a fundamental contributor to COPD. American Journal of Physiology - Lung Cellular and Molecular Physiology, 313(3), L453-L465. DOI Scopus9 WoS7 Europe PMC8
2017	Gibson, P., Yang, I., Upham, J., Reynolds, P., Hodge, S., James, A., . . . Simpson, J. (2017). Effect of azithromycin on asthma exacerbations and quality of life in adults with persistent uncontrolled asthma (AMAZES): a randomised, double-blind, placebo-controlled trial. The Lancet, 390(10095), 659-668. DOI Scopus83 Europe PMC40
2017	Ween, M., Whittall, J., Hamon, R., Reynolds, P., & Hodge, S. (2017). Phagocytosis and Inflammation: Exploring the effects of the components of E-cigarette vapor on macrophages. Physiological Reports, 5(16), 1-12. DOI Scopus6 Europe PMC4
2017	Tran, H., Jersmann, H., Truong, T., Hamon, R., Roscioli, E., Ween, M., . . . Hodge, S. (2017). Disrupted epithelial/macrophage crosstalk via Spinster homologue 2-mediated S1P signaling may drive defective macrophage phagocytic function in COPD. PLoS ONE, 12(11), e0179577-1-e0179577-14. DOI Scopus5 WoS3 Europe PMC1
2017	Roscioli, E., Hamon, R., Ruffin, R., Grant, J., Hodge, S., Zalewski, P., & Lester, S. (2017). BIRC3 single nucleotide polymorphism associate with asthma susceptibility and the abundance of eosinophils and neutrophils. Journal of Asthma, 54(2), 116-124. DOI Scopus2 WoS3 Europe PMC2
2017	Barnawi, J., Jersmann, H., Haberberger, R., Hodge, S., & Meech, R. (2017). Reduced DNA methylation of sphingosine-1 phosphate receptor 5 in alveolar macrophages in COPD: A potential link to failed efferocytosis. Respirology, 22(2), 315-321. DOI Scopus9 WoS11 Europe PMC10
2017	Hodge, G., Hodge, S., Yeo, A., Nguyen, P., Hopkins, E., Holmes-Liew, C., . . . Holmes, M. (2017). BOS is associated with increased cytotoxic proinflammatory CD8 T, NKT-like, and NK cells in the small airways. Transplantation, 101(10), 2469-2476. DOI Scopus10
2017	Hodge, S., Tran, H., Hamon, R., Roscioli, E., Hodge, G., Jersmann, H., . . . Wilbert, S. (2017). Nonantibiotic macrolides restore airway macrophage phagocytic function with potential anti-inflammatory effects in chronic lung diseases. American Journal of Physiology - Lung Cellular and Molecular Physiology, 312(5), L678-L687. DOI Scopus14 WoS13 Europe PMC10
2016	Barnawi, J., Tran, H., Roscioli, E., Hodge, G., Jersmann, H., Haberberger, R., & Hodge, S. (2016). Pro-phagocytic Effects of Thymoquinone on Cigarette Smoke-exposed Macrophages Occur by Modulation of the Sphingosine-1-phosphate Signalling System. COPD: Journal of Chronic Obstructive Pulmonary Disease, 13(5), 653-661. DOI Scopus7 WoS7 Europe PMC4
2016	Hodge, S., Jersmann, H., & Reynolds, P. (2016). The effect of colonization with potentially pathogenic microorganisms on efferocytosis in chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine, 194(7), 912-915. DOI Scopus1 WoS2 Europe PMC1
2016	Hodge, G., Roscioli, E., Jersmann, H., Tran, H. B., Holmes, M., Reynolds, P. N., & Hodge, S. (2016). Steroid resistance in COPD is associated with impaired molecular chaperone Hsp90 expression by pro-inflammatory lymphocytes. RESPIRATORY RESEARCH, 17(1), 12 pages. DOI WoS8 Europe PMC6
2016	Finan, K., Hodge, G., Reynolds, A., Hodge, S., Holmes, M., Baker, A., & Reynolds, P. (2016). Erratum: Corrigendum to “In vitro susceptibility to the pro-apoptotic effects of TIMP-3 gene delivery translates to greater in vivo efficacy versus gene delivery for TIMPs-1 or -2” (Lung Cancer (2006) 53(3) (273–284) (S0169500206003308) (10.1016/j.lungcan.2006.06.006)). Lung Cancer, 101, 149. DOI
2016	Simpson, J., Yang, I., Upham, J., Reynolds, P., Hodge, S., James, A., . . . Gibson, P. (2016). Periostin levels and eosinophilic inflammation in poorly-controlled asthma. BMC Pulmonary Medicine, 16(1), 67-1-67-7. DOI Scopus23 WoS20 Europe PMC15
2016	Simpson, J., Daly, J., Baines, K., Yang, I., Upham, J., Reynolds, P., . . . Gibson, P. (2016). Airway dysbiosis: Haemophilus influenza and Tropheryma in poorly controlled asthma. European Respiratory Journal, 47(3), 792-800. DOI Scopus45 WoS47 Europe PMC38
2016	Ween, M., Ahern, J., Carroll, A., Hodge, G., Pizzutto, S., Jersmann, H., . . . Hodge, S. (2016). A small volume technique to examine and compare alveolar macrophage phagocytosis of apoptotic cells and non typeable Haemophilus influenzae (NTHi). Journal of Immunological Methods, 429, 7-14. DOI Scopus7 WoS8 Europe PMC6
2016	Tran, H., Barnawi, J., Ween, M., Hamon, R., Roscioli, E., Hodge, G., . . . Hodge, S. (2016). Cigarette smoke inhibits efferocytosis via deregulation of sphingosine kinase signaling: reversal with exogenous S1P and the S1P analogue FTY720. Journal of Leukocyte Biology, 100(1), 195-202. DOI Scopus10 WoS9 Europe PMC8
2016	Hodge, S., Hodge, G., Simpson, J., Yang, I., Upham, J., James, A., . . . Reynolds, P. (2016). Blood cytotoxic/inflammatory mediators in non-eosinophilic asthma. Clinical & Experimental Allergy, 46(1), 60-70. DOI Scopus5 WoS5 Europe PMC3
2016	Simpson, J., Carroll, M., Yang, I., Reynolds, P., Hodge, S., James, A., . . . Upham, J. (2016). Reduced antiviral interferon production in poorly controlled asthma is associated with neutrophilic inflammation and high-dose inhaled corticosteroids. Chest, 149(3), 704-713. DOI Scopus11 WoS10 Europe PMC7
2016	Hodge, S., Upham, J., Pizzutto, S., Petsky, H., Yerkovich, S., Baines, K., . . . Chang, A. (2016). Is alveolar macrophage phagocytic dysfunction in children with protracted bacterial bronchitis a forerunner to bronchiectasis?. Chest, 149(2), 508-515. DOI Scopus17 WoS16 Europe PMC13
2016	Hodge, G., & Hodge, S. (2016). Steroid resistant CD8⁺CD28null NKT-like pro-inflammatory cytotoxic cells in chronic obstructive pulmonary disease. Frontiers in Immunology, 7(DEC), 617-1-617-6. DOI Scopus10 WoS9 Europe PMC7
2015	Hodge, G., Upham, J., Chang, A., Baines, K., Yerkovich, S., Pizzutto, S., & Hodge, S. (2015). Increased peripheral blood pro-inflammatory/cytotoxic lymphocytes in children with bronchiectasis. PLoS ONE, 10(8), e0133695-1-e0133695-13. DOI Scopus6 WoS5 Europe PMC4
2015	Hodge, G. (2015). Histone Deacetylase 2 is Decreased in Peripheral Blood Cytotoxic/Pro-Inflammatory CD8+ T and NKT-Like Lymphocytes Following Lung Transplant. The Journal of Heart and Lung Transplantation, 34(4), S266. DOI
2015	Hone, L., Jarden, A., Duncan, S., & Schofield, G. (2015). Flourishing in New Zealand Workers : Associations with Lifestyle Behaviors, Physical Health, Psychosocial, and Work-Related Indicators. Journal of Occupational and Environmental Medicine, 57(9), 973-983. DOI Scopus13 WoS11 Europe PMC2
2015	Stewart, T., Duncan, S., Chaix, B., Kestens, Y., Schipperijn, J., & Schofield, G. (2015). A novel assessment of adolescent mobility: A pilot study. International Journal of Behavioral Nutrition and Physical Activity, 12(1), 11 pages. DOI Scopus13 WoS11 Europe PMC6
2015	Simpson, J., Yang, I., Upham, J., Reynolds, P., Hodge, S., James, A., . . . Gibson, P. (2015). SPUTUM AND SERUM PERIOSTIN LEVELS ARE ASSOCIATED WITH, BUT DO NOT PREDICT SPUTUM EOSINOPHIL PROPORTION IN SEVERE ASTHMA. RESPIROLOGY, 20, 68. WoS1
2015	Gao, P., Gibson, P., Baines, K., Yang, I., Upham, J., Reynolds, P., . . . Simpson, J. (2015). Anti-inflammatory deficiencies in neutrophilic asthma: reduced galectin-3 and IL-1RA/IL-1β. Respiratory Research, 16(1), 5-1-5-10. DOI Scopus32 WoS30 Europe PMC23
2015	Hodge, S., Hodge, G., Holmes, M., Jersmann, H., & Reynolds, P. N. (2015). Increased CD8 T-cell granzyme B in COPD is suppressed by treatment with low-dose azithromycin. Respirology, 20(1), 95-100. DOI Scopus5 WoS4 Europe PMC3
2015	Barnawi, J., Hai, T., Jersmann, H., Pitson, S., Roscioli, E., Hodge, G., . . . Hodge, S. (2015). Potential link between the Sphingosine-1-Phosphate (S1P) system and defective alveolar macrophage phagocytic function in Chronic Obstructive Pulmonary Disease (COPD). PLoS One, 10(10), e0122771-1-e0122771-21. DOI Scopus16 WoS15 Europe PMC12
2015	Hodge, G., Jersmann, H., Tran, H., Roscioli, E., Holmes, M., Reynolds, P., & Hodge, S. (2015). Lymphocyte senescence in COPD is associated with decreased histone deacetylase 2 expression by pro-inflammatory lymphocytes. Respiratory Research, 16(1), 130-1-130-11. DOI Scopus15 WoS1 Europe PMC11
2015	Hodge, G., Jersmann, H., Tran, H., Holmes, M., Reynolds, P., & Hodge, S. (2015). Lymphocyte senescence in COPD is associated with loss of glucocorticoid receptor expression by pro-inflammatory/cytotoxic lymphocytes. Respiratory Research, 16(1), 2-1-2-9. DOI Scopus18 WoS25 Europe PMC13
2014	Tran, H. B., Ahern, J., Hodge, G., Holt, P., Dean, M. M., Reynolds, P. N., & Hodge, S. (2014). Oxidative stress decreases functional airway mannose binding lectin in COPD. PLoS One, 9(6), 1-6. DOI Scopus17 WoS18 Europe PMC14
2014	Zhang, X., Simpson, J., Powell, H., Yang, I., Upham, J., Reynolds, P., . . . Gibson, P. (2014). Full blood count parameters for the detection of asthma inflammatory phenotypes. Clinical and Experimental Allergy, 44(9), 1137-1145. DOI Scopus85 WoS83 Europe PMC52
2014	Hodge, G., Barnawi, J., Jurisevic, C., Moffat, D., Holmes, M., Reynolds, P., . . . Hodge, S. (2014). Lung cancer is associated with decreased expression of perforin, granzyme B and interferon (IFN)-γ by infiltrating lung tissue T cells, natural killer (NK) T-like and NK cells. Clinical and Experimental Immunology, 178(1), 79-85. DOI Scopus32 WoS34 Europe PMC18
2014	Holt, P., Barnawi, J., Hodge, G., Jermann, H., Reynolds, P., Pitson, S., . . . Hodge, S. (2014). IMPAIRMENT OF EFFEROCYTOSIS BY CIGARETTE SMOKE CAN BE REVERSED IN THP-1 MACROPHAGES BY STIMULATION WITH SPHINGOSINE-1-PHOSPHATE. RESPIROLOGY, 19, 47.
2014	Simpson, J., Gibson, P., Yang, I., Upham, J., James, A., Reynolds, P., & Hodge, S. (2014). Altered sputum granzyme B and granzyme B/proteinase inhibitor-9 in patients with non-eosinophilic asthma. Respirology, 19(2), 280-287. DOI Scopus6 WoS6 Europe PMC6
2014	Hodge, G., Hodge, S., Holmes-Liew, C., Reynolds, P., & Holmes, M. (2014). Loss of glucocorticoid receptor from pro-inflammatory T cells after lung transplant. Journal of Heart and Lung Transplantation, 33(9), 957-962. DOI Scopus7 WoS6 Europe PMC5
2014	Hodge, G., Holmes, M., Jersmann, H., Reynolds, P., & Hodge, S. (2014). Targeting peripheral blood pro-inflammatory cytotoxic lymphocytes by inhibiting CD137 expression: novel potential treatment for COPD. BMC Pulmonary Medicine, 14(1), 85-1-85-11. DOI Scopus7 WoS7 Europe PMC5
2014	Hamon, R., Homan, C., Tran, H., Mukaro, V., Lester, S., Roscioli, E., . . . Hodge, S. (2014). Zinc and zinc transporters in macrophages and their roles in efferocytosis in COPD. PLoS ONE, 9(10), e110056-1-e110056-9. DOI Scopus17 WoS16 Europe PMC13
2014	Holt, P., Tran, H., Hodge, G., Reynolds, P., & Hodge, S. (2014). MICROBIAL GROWTH DOES NOT INFLUENCE THE PHAGOCYTIC DEFECT IN ALVEOLAR MACROPHAGES IN COPD. RESPIROLOGY, 19, 62.
2013	Mukaro, V., Bylund, J., Hodge, G., Holmes, M., Jersmann, H., Reynolds, P., & Hodge, S. (2013). Lectins offer new perspectives in the development of macrophage-targeted therapies for COPD/emphysema. PLoS One, 8(2), 1-10. DOI Scopus19 WoS16 Europe PMC13
2013	Hodge, G., Mukaro, V., Holmes, M., Reynolds, P., & Hodge, S. (2013). Enhanced cytotoxic function of natural killer and natural killer T-like cells associated with decreased CD94 (Kp43) in the chronic obstructive pulmonary disease airway. Respirology, 18(2), 369-376. DOI Scopus26 WoS23 Europe PMC23
2013	Simpson, J., Gibson, P., Yang, I., Upham, J., James, A., Reynolds, P., . . . AMAZES Study Research Group. (2013). Impaired macrophage phagocytosis in non-eosinophilic asthma. Clinical and Experimental Allergy, 43(1), 29-35. DOI Scopus62 WoS59 Europe PMC44
2013	Hodge, S., & Reynolds, P. (2013). Regarding comments by Persson et al. (Airway, apoptosis, and asthma) to JL Simpson, PG Gibson, IA Yang, J Upham, A James, PN Reynolds. S Hodge and AMAZES Study Research. Impaired macrophage phagocytosis in noneosinophilic asthma. Clinical and Experimental Allergy, 43(9), 1086-1088. DOI
2013	Hodge, S., Dean, M., & Eisen, D. (2013). Lectins as potential adjunct therapeutics for COPD/Emphysema?. Journal of Pulmonary & Respiratory Medicine, 3(5), e130-e131. DOI
2013	Hodge, G., Hodge, S., Reynolds, P., & Holmes, M. (2013). Targeting peripheral blood pro-inflammatory CD28null T cells and natural killer T-like cells by inhibiting CD137 expression: Possible relevance to treatment of bronchiolitis obliterans syndrome. Journal of Heart and Lung Transplantation, 32(11), 1081-1089. DOI Scopus4 WoS4 Europe PMC2
2013	Hodge, G., Holmes, M., Jersmann, H., Reynolds, P., & Hodge, S. (2013). The drug efflux pump Pgp1 in pro-inflammatory lymphocytes is a target for novel treatment strategies in COPD. Respiratory Research (Online), 14(63), 1-8. DOI Scopus15 WoS12 Europe PMC11
2013	Hodge, G., Hodge, S., Ahern, J., Liew, C., Reynolds, P., & Holmes, M. (2013). Up-regulation of alternate co-stimulatory molecules on proinflammatory CD28null T cells in bronchiolitis obliterans syndrome. Clinical and Experimental Immunology, 173(1), 150-160. DOI Scopus7 WoS7 Europe PMC7
2013	Dehle, F., Mukaro, V., Jurisevic, C., Moffat, D., Ahern, J., Hodge, G., . . . Hodge, S. (2013). Defective lung macrophage function in lung cancer±chronic obstructive pulmonary disease (COPD/emphysema)-mediated by cancer cell production of PGE2?. PLoS One, 8(4), 1-6. DOI Scopus14 WoS12 Europe PMC10
2012	Hodge, S. (2012). Pulmonary macrophage-targeted therapies-the way forward in chronic inflammatory lung diseases?. Journal of Pulmonary & Respiratory Medicine, 2(1), 105-106. DOI
2012	Hodge, G., Hodge, S., Holmes-Liew, C., Reynolds, P., & Holmes, M. (2012). Bronchiolitis obliterans syndrome is associated with increased peripheral blood natural killer and natural killer T-like granzymes, perforin, and T-helper-type 1 pro-inflammatory cytokines. Journal of Heart and Lung Transplantation, 31(8), 888-895. DOI Scopus15 WoS15 Europe PMC9
2012	Hodge, G., Reynolds, P., Holmes, M., & Hodge, S. (2012). Differential expression of pro-inflammatory cytokines in intra-epithelial T cells between trachea and bronchi distinguishes severity of COPD. Cytokine (Online), 60(3), 843-848. DOI Scopus8 WoS8 Europe PMC8
2012	Hodge, G., Hodge, S., Chambers, D., Reynolds, P., & Holmes, M. (2012). Increased expression of graft intraepithelial T-cell pro-inflammatory cytokines compared with native lung during episodes of acute rejection. Journal of Heart and Lung Transplantation, 31(5), 538-544. DOI Scopus7 WoS8 Europe PMC5
2012	Soriano, C., Mukaro, V., Hodge, G., Ahern, J., Holmes, M., Jersmann, H., . . . Hodge, S. (2012). Increased proteinase inhibitor-9 (PI-9) and reduced granzyme B in lung cancer: mechanism for immune evasion?. Lung Cancer, 77(1), 38-45. DOI Scopus23 WoS25 Europe PMC17
2012	Hodge, G., Hodge, S., Liew, C., Reynolds, P., & Holmes, M. (2012). Increased natural killer T-like cells are a major source of pro-inflammatory cytokines and granzymes in lung transplant recipients. Respirology, 17(1), 155-163. DOI Scopus28 WoS25 Europe PMC18
2012	Hodge, S., & Reynolds, P. (2012). Low-dose azithromycin improves phagocytosis of bacteria by both alveolar and monocyte-derived macrophagesin chronic obstructive pulmonary disease subjects. Respirology, 17(5), 802-807. DOI Scopus40 WoS38 Europe PMC33
2012	Williden, M., Duncan, S., & Schofield, G. (2012). Do health behaviours cluster in a working population in New Zealand?. Health Promotion Journal of Australia, 23(3), 234-236. DOI Scopus2 WoS2 Europe PMC1
2012	Hodge, S., & Reynolds, P. (2012). Low-dose azithromycin improves phagocytosis of bacteria by both alveolar and monocyte-derived macrophagesin COPD subjects. COPD: Journal of Chronic Obstructive Pulmonary Disease, 9(2), 206. DOI
2011	Hodge, S. (2011). Learning to manage: Transformative outcomes of competency-based training. Australian Journal of Adult Learning, 51(3), 498-517. Scopus9 WoS7
2011	Mukaro, V., & Hodge, S. (2011). Airway clearance of apoptotic cells in COPD. Current Drug Targets, 12(4), 460-468. DOI Scopus19 WoS18 Europe PMC14
2011	Chambers, D., Hodge, S., Hodge, G., Yerkovich, S., Kermeen, F., Reynolds, P., . . . Hopkins, P. (2011). A novel approach to the assessment of lymphocytic bronchiolitis after lung transplantation-transbronchial brush. Journal of Heart and Lung Transplantation, 30(5), 544-551. DOI Scopus10 WoS9 Europe PMC4
2011	Cordts, F., Pitson, S., Tabeling, C., Gibbins, I., Moffat, D., Jersmann, H., . . . Haberberger, R. (2011). Expression profile of the sphingosine kinase signalling system in the lung of patients with chronic obstructive pulmonary disease. Life Sciences, 89(21-22), 806-811. DOI Scopus20 WoS18 Europe PMC17
2011	Hodge, G., Mukaro, V., Reynolds, P., & Hodge, S. (2011). Role of increased CD8/CD28(null) T cells and alternative co-stimulatory molecules in chronic obstructive pulmonary disease. Clinical and Experimental Immunology, 166(1), 94-102. DOI Scopus31 WoS32 Europe PMC23
2011	Hodge, S., Dean, M., Hodge, G., Holmes, M., & Reynolds, P. (2011). Decreased efferocytosis and mannose binding lectin in the airway in bronchiolitis obliterans syndrome. Journal of Heart and Lung Transplantation, 30(5), 589-595. DOI Scopus17 WoS16 Europe PMC12
2011	Hodge, S., Matthews, G., Mukaro, V., Ahern, J., Shivam, A., Hodge, G., . . . Reynolds, P. (2011). Cigarette Smoke-induced Changes to Alveolar Macrophage Phenotype and Function are Improved by Treatment with Procysteine. American Journal of Respiratory Cell and Molecular Biology, 44(5), 673-681. DOI Scopus83 WoS80 Europe PMC64
2011	Hodge, G., Scott, J., Osborn, M., To, L., Zola, H., Hodge, S., & Revesz, T. (2011). Increased T regulatory cells and decreased Th1 pro-inflammatory cytokines correlate with culture-positive infection in febrile neutropenia childhood oncology patients. Cytokine (Online), 53(3), 286-288. DOI Scopus4 WoS4 Europe PMC4
2010	Hodge, G., Hodge, S., Liew, C., Chambers, D., Hopkins, P., Reynolds, P., & Holmes, M. (2010). Time post-lung transplant correlates with increasing peripheral blood T cell granzyme B and proinflammatory cytokines. Clinical and Experimental Immunology, 2009(3), 1-7. DOI Scopus12 WoS10 Europe PMC9
2010	Hodge, S., Matthews, G., Dean, M., Ahern, J., Djukic, M., Hodge, G., . . . Reynolds, P. (2010). Therapeutic role for mannose-binding lectin in cigarette smoke-induced lung inflammation? Evidence from a murine model. American Journal of Respiratory Cell and Molecular Biology, 42(2), 235-242. DOI Scopus34 WoS30 Europe PMC28
2010	Hodge, G., Hodge, S., Liew, C., Chambers, D., Hopkins, P., Reynolds, P., & Holmes, M. (2010). Lymphocytic bronchiolitis is associated with inadequate suppression of blood T-cell granzyme B, IFN-γ, and TNF-α. Transplantation, 89(10), 1283-1289. DOI Scopus11 WoS9 Europe PMC7
2010	Hodge, G., Hodge, S., Liew, C., Reynolds, P., Chambers, D., Hopkins, P., & Holmes, M. (2010). Lymphocytic Bronchiolitis Is Associated With Inadequate Suppression Of Peripheral Blood T-cell Granzyme B, IFN gamma And TNF alpha- Possible Link With Obliterative Bronchiolitis?. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 181, 1 page.
2009	Hodge, G., Hodge, S., Chambers, D., Reynolds, P., & Holmes, M. (2009). Bronchiolitis Obliterans Syndrome Is Associated with Absence of Suppression of Peripheral Blood Th1 Pro-Inflammatory Cytokines.. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 179, 1 page.
2009	Hodge, S., Hodge, G., Ahern, J., Liew, C., Hopkins, P., Chambers, D., . . . Holmes, M. (2009). Increased levels of T cell granzyme b in bronchiolitis obliterans syndrome are not suppressed adequately by current immunosuppressive regimens. Clinical and Experimental Immunology, 158(2), 230-236. DOI Scopus25 WoS24 Europe PMC20
2009	Hodge, G., Hodge, S., Chambers, D., Reynolds, P., & Holmes, M. (2009). Bronchiolitis Obliterans Syndrome is associated with absence of suppression of peripheral blood Th1 proinflammatory cytokines. Transplantation, 88(2), 211-218. DOI Scopus27 WoS26 Europe PMC20
2009	Brozyna, S., Ahern, J., Hodge, G., Nairn, J., Holmes, M., Reynolds, P., & Hodge, S. (2009). Chemotactic Mediators of Th1 T-cell Trafficking in Smokers and COPD Patients. COPD, 6(1), 4-16. DOI Scopus31 WoS28 Europe PMC24
2009	Hodge, S., Holmes, M., Banerjee, B., Musk, M., Kicic, A., Waterer, G., . . . Chambers, D. (2009). Posttransplant bronchiolitis obliterans syndrome is associated with bronchial epithelial to mesenchymal transition. American Journal of Transplantation, 9(4), 727-733. DOI Scopus53 WoS42 Europe PMC35
2009	Duncan, J., Duncan, E., & Schofield, G. (2009). Accuracy of body mass index (BMI) thresholds for predicting excess body fat in girls from five ethnicities. Asia Pacific Journal of Clinical Nutrition, 18(3), 404-411. Scopus33 WoS34 Europe PMC18
2008	Duncan, E., Scott Duncan, J., & Schofield, G. (2008). Pedometer-determined physical activity and active transport in girls. International Journal of Behavioral Nutrition and Physical Activity, 5(1), 9 pages. DOI Scopus60 WoS59 Europe PMC24
2008	Duncan, J., Hopkins, W., Schofield, G., & Duncan, E. (2008). Effects of weather on pedometer-determined physical activity in children. Medicine and Science in Sports and Exercise, 40(8), 1432-1438. DOI Scopus57 WoS60 Europe PMC36
2008	Duncan, J., Schofield, G., Duncan, E., & Rush, E. (2008). Risk factors for excess body fatness in New Zealand children. Asia Pacific Journal of Clinical Nutrition, 17(1), 138-147. Scopus30 WoS31 Europe PMC21
2008	Hodge, S. (2008). Jacques Lacan and education: a critical introduction. AUSTRALIAN JOURNAL OF ADULT LEARNING, 48(3), 566-571.
2008	Hodge, S., Hodge, G., Jersmann, H., Matthews, G., Ahern, J., Holmes, M., & Reynolds, P. (2008). Azithromycin improves macrophage phagocytic function and expression of mannose receptor in chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine, 178(2), 139-148. DOI Scopus155 WoS143 Europe PMC115
2008	Hodge, G., Hodge, S., Reynolds, P., & Holmes, M. (2008). Airway infection in stable lung transplant patients is associated with decreased intracellular T-helper type 1 pro-inflammatory cytokines in bronchoalveolar lavage T-cell subsets. Transplant Infectious Disease Online, 10(2), 99-105. DOI Scopus8 WoS4 Europe PMC2
2007	Hodge, S., Hodge, G., Ahern, J., Jersmann, H., Holmes, M., & Reynolds, P. (2007). Smoking alters alveolar macrophage recognition and phagocytic ability. American Journal of Respiratory Cell and Molecular Biology, 37(6), 748-755. DOI Scopus203 WoS185 Europe PMC146
2007	Hodge, G., Nairn, J., Holmes, M., Reynolds, P., & Hodge, S. (2007). Increased intracellular T helper 1 proinflammatory cytokine production in peripheral blood, bronchoalveolar lavage and intraepithelial T cells of COPD subjects. Clinical and Experimental Immunology, 150(1), 22-29. DOI Scopus96 WoS89 Europe PMC69
2007	Reynolds, A., Xia, W., Holmes, M., Hodge, S., Danilov, S., Curiel, D., . . . Reynolds, P. (2007). Bone morphogenetic protein type 2 receptor gene therapy attenuates hypoxic pulmonary hypertension. American Journal of Physiology-Lung Cellular and Molecular Physiology, 292(5), L1182-L1192. DOI Scopus89 WoS75 Europe PMC57
2007	Hodge, G., Hodge, S., Chambers, D., Reynolds, P., & Holmes, M. (2007). Acute lung transplant rejection is associated with localized increase in T-cell IFNγ and TNFα proinflammatory cytokines in the airways. Transplantation, 84(11), 1452-1458. DOI Scopus23 WoS20 Europe PMC18
2007	Scott Duncan, J., Schofield, G., & Duncan, E. (2007). Step count recommendations for children based on body fat. Preventive Medicine, 44(1), 42-44. DOI Scopus55 WoS52 Europe PMC27
2007	Duncan, J., Schofield, G., Duncan, E., & Hinckson, E. (2007). Effects of age, walking speed, and body composition on pedometer accuracy in children. Research Quarterly for Exercise and Sport, 78(5), 420-428. DOI Scopus48 WoS46 Europe PMC26
2006	Duncan, J., Schofield, G., & Duncan, E. (2006). Pedometer-determined physical activity and body composition in New Zealand children. Medicine and Science in Sports and Exercise, 38(8), 1402-1409. DOI Scopus102 WoS97 Europe PMC46
2006	Hodge, G., Osborn, M., Hodge, S., Nairn, J., Tapp, H., Kirby, M., . . . Zola, H. (2006). Rapid simultaneous measurement of multiple cytokines in childhood oncology patients with febrile neutropenia: increased interleukin (IL)-8 or IL-5 correlates with culture-positive infection. British Journal of Haematology, 132(2), 247-248. DOI Scopus21 WoS21 Europe PMC16
2006	Finan, K., Hodge, G., Reynolds, A., Hodge, S., Holmes, M., Baker, A., & Reynolds, P. (2006). In vitro susceptibility to the pro-apoptotic effects of TIMP-3 gene delivery translates to greater in vivo efficacy versus gene delivery for TIMPs-1 or-2. Lung Cancer, 53(3), 273-284. DOI Scopus30 WoS28 Europe PMC24
2006	Hodge, S., Hodge, G., Brozyna, S., Jersmann, H., Holmes, M., & Reynolds, P. (2006). Azithromycin increases phagocytosis of apoptotic bronchial epithelial cells by alveolar macrophages. European Respiratory Journal, 28(3), 486-495. DOI Scopus121 WoS106 Europe PMC80
2006	Hodge, G., Hodge, S., Reynolds, P., & Holmes, M. (2006). Compartmentalization of intracellular proinflammatory cytokines in bronchial intraepithelial T cells of stable lung transplant patients. Clinical and Experimental Immunology, 145(3), 413-419. DOI Scopus20 WoS17 Europe PMC13
2006	Hodge, S., Hodge, G., Nairn, J., Holmes, M., & Reynolds, P. (2006). Increased airway granzyme b and perforin in current and ex-smoking COPD subjects. COPD: Journal of Chronic Obstructive Pulmonary Disease, 3(4), 179-187. DOI Scopus58 Europe PMC38
2005	Hodge, G., Hodge, S., Reynolds, P., & Holmes, M. (2005). Increased intracellular pro- and anti-inflammatory cytokines in bronchoalveolar lavage T cells of stable lung transplant patients. Transplantation, 80(8), 1040-1045. DOI Scopus20 WoS17 Europe PMC13
2005	Hodge, G., Markus, C., Nairn, J., & Hodge, S. (2005). Effect of blood storage conditions on leucocyte intracellular cytokine production. Cytokine, 32(1), 7-11. DOI Scopus8 WoS8 Europe PMC7
2005	Hodge, S., Hodge, G., Reynolds, P., & Holmes, M. (2005). Differential rates of apoptosis in bronchoalveolar lavage and blood of lung transplant patients. Journal of Heart and Lung Transplantation, 24(9), 1305-1314. DOI Scopus13 WoS12 Europe PMC9
2005	Hodge, G., Hodge, S., Nairn, J., Tippett, M., Holmes, M., & Reynolds, P. (2005). Poststorage leuko-depleted plasma inhibits T-cell proliferation and Th1 response in vitro: Characterization of TGF b-1 as an important immunomodulatory component in stored blood. Transplantation, 80(1), 95-101. DOI Scopus10 WoS6 Europe PMC4
2005	Hodge, S., Hodge, G., Holmes, M., & Reynolds, P. (2005). Increased peripheral blood T-cell apoptosis and decreased Bcl-2 in chronic obstructive pulmonary disease. Immunology and Cell Biology, 83(2), 160-166. DOI Scopus21 WoS15 Europe PMC13
2005	Hodge, S., Hodge, G., Holmes, M., & Reynolds, P. (2005). Increased airway epithelial and T-cell apoptosis in COPD remains despite smoking cessation. European Respiratory Journal, 25(3), 447-454. DOI Scopus165 WoS147 Europe PMC120
2005	Hodge, G., Hodge, S., Reynolds, P., & Holmes, M. (2005). Up-regulation of Interleukin-8, Interleukin-10, Monocyte Chemotactic Protein-1, and Monocyte Chemotactic Protein-3 in Peripheral Blood Monocytes in Stable Lung Transplant Recipients: Are Immunosuppression Regimens Working?. Transplantation, 79(4), 387-391. DOI Scopus9 WoS9 Europe PMC4
2005	Hodge, G., Hodge, S., Reynolds, P., & Holmes, M. (2005). Intracellular cytokines in blood T cells in lung transplant patients - a more relevant indicator of immunosuppression than drug levels. Clinical and Experimental Immunology, 139(1), 159-164. DOI Scopus42 WoS32 Europe PMC25
2004	Hodge, G., Hodge, S., Haslam, R., McPhee, A., Sepulveda, H., Morgan, E., . . . Zola, H. (2004). Rapid simultaneous measurement of multiple cytokines using 100 µl sample volumes - association with neonatal sepsis. Clinical and Experimental Immunology, 137(2), 402-407. DOI Scopus51 WoS42 Europe PMC28
2004	Hodge, S., Hodge, G., Holmes, M., & Reynolds, P. (2004). Flow cytometric characterization of cell populations in bronchoalveolar lavage and bronchial brushings from patients with chronic obstructive pulmonary disease. Cytometry Part B - Clinical cytometry, 61B(1), 27-34. DOI Scopus45 WoS41 Europe PMC27
2004	Hodge, G., Hodge, S., Han, P., & Haslam, R. (2004). Multiple leucocyte activation markers to detect neonatal infection. Clinical and Experimental Immunology, 135(1), 125-129. DOI Scopus38 WoS29 Europe PMC24
2004	Kuchel, H., Siebert, B., Bottema, C., Webb, G., Crawford, A., Duncan, S., . . . Pitchford, W. (2004). Physical mapping of the stearoyl-CoA desaturase (SCD) locus in sheep. Animal Genetics, 35(2), 163. DOI Scopus5 WoS4 Europe PMC2
2003	Hodge, G., Hodge, S., Markus, C., Lawrence, A., & Han, P. (2003). A marked decrease in L-selectin expression by leucocytes in infants with Bordetella pertussis infection: leucocytosis explained?. Respirology, 8(2), 157-162. DOI Scopus19 WoS17 Europe PMC15
2003	Hodge, S., Hodge, G., Reynolds, P., Scicchitano, R., & Holmes, M. (2003). Increased production of TGF-β and apoptosis of T lymphocytes isolated from peripheral blood in COPD. American Journal of Physiology - Lung Cellular and Molecular Physiology, 285(2), L492-L499. DOI Scopus82 WoS65 Europe PMC47
2003	Hodge, S., Hodge, G., Scicchitano, R., Reynolds, P., & Holmes, M. (2003). Alveolar macrophages from subjects with chronic obstructive pulmonary disease are deficient in their ability to phagocytose apoptotic airway epithelial cells. Immunology and Cell Biology, 81(4), 289-296. DOI Scopus268 WoS237 Europe PMC191
2003	Hodge, S., Hodge, G., Scicchitano, R., Reynolds, P., & Holmes, M. (2003). Erratum: Alveolar macrophages from subjects with chronic obstructive pulmonary disease are deficient in their ability to phagocytose apoptotic airway epithelial cells (Immunology and Cell Biology (2003) 81 (289-296)). Immunology and Cell Biology, 81(6), 499. DOI
2002	Hodge, S., Hodge, G., Flower, R., Reynolds, P., Scicchitano, R., & Holmes, M. (2002). Up-regulation of production of TGF-β and IL-4 and down-regulation of IL-6 by apoptotic human bronchial epithelial cells. Immunology and Cell Biology, 80(6), 537-543. DOI Scopus31 WoS29 Europe PMC16
2002	Hodge, G., Hodge, S., & Han, P. (2002). Allium sativum (garlic) suppresses leukocyte inflammatory cytokine production in vitro: Potential therapeutic use in the treatment of inflammatory bowel disease. Cytometry Part A, 48(4), 209-215. DOI Scopus116 WoS110 Europe PMC65
2001	Hodge, S., Hodge, G., Flower, R., & Han, P. (2001). Cord blood leucocyte expression of functionally significant molecules involved in the regulation of cellular immunity. Scandinavian Journal of Immunology, 53(1), 72-78. DOI Scopus27 WoS25 Europe PMC17
2001	Hodge, S., Hodge, G., Holmes, M., Flower, R., & Scicchitano, R. (2001). Interleukin-4 and tumour necrosis factor-α inhibit transforming growth factor-β production in a human bronchial epithelial cell line: Possible relevance to inflammatory mechanisms in chronic obstructive pulmonary disease. Respirology, 6(3), 205-211. DOI Scopus12 Europe PMC6
2001	Hodge, S., & Hodge, G. (2001). Flow cytometr1c analysis of bal: comparison with manual cell counting methodsand practical application to quantify apoptotic cell populations in lung disease. Respirology, 6(SUPPL. 1).
2000	Hodge, G., Hodge, S., & Han, P. (2000). Increased levels of apoptosis of leukocyte subsets in cultured pbmcs compared to whole blood as shown by annexin v binding: relevance to cytokine production. Cytokine, 12(12), 1763-1768. DOI Scopus42 WoS40 Europe PMC30
2000	Hodge, S., Hodge, G., Flower, R., & Han, P. (2000). Surface and intracellular interleukin-2 receptor expression on various resting and activated populations involved in cell-mediated immunity in human peripheral blood. Scandinavian Journal of Immunology, 51(1), 67-72. DOI Scopus27 WoS26 Europe PMC18
1999	Hodge, G., Lloyd, J., Hodge, S., Story, C., & Han, P. (1999). Functional lymphocyte immunophenotypes observed in thalassaemia and haemophilia patients receiving current blood product preparations. British Journal of Haematology, 105(3), 817-825. DOI Scopus26 WoS29 Europe PMC17
1999	Hodge, S., Hodge, G., Flower, R., & Han, P. (1999). Methyl-prednisolone up-regulates monocyte interleukin-10 production in stimulated whole blood. Scandinavian Journal of Immunology, 49(5), 548-553. DOI Scopus74 WoS66 Europe PMC46
1998	Hodge, S., Hodge, G., Flower, R., & Han, P. (1998). Surface activation markers of T lymphocytes: role in the detection of infection in neonates. Clinical and Experimental Immunology, 113(1), 33-38. DOI Scopus38 WoS30 Europe PMC27
1998	Forbes, B., Turner, D., Hodge, S., McNeil, K., Forsberg, G., & Wallace, J. (1998). Localization of an Insulin-like Growth Factor (IGF) Binding Site of Bovine IGF Binding Protein-2 Using Disulfide Mapping and Deletion Mutation Analysis of the C-terminal Domain. Journal of Biological Chemistry, 273(8), 4647-4652. DOI Scopus67 WoS66 Europe PMC31
1994	BEROYZ, G., CASALE, R., FARREIROS, A., PALERMO, M., MARGULIES, M., VOTO, L., . . . FIDALGO, C. (1994). CLASP - A RANDOMIZED TRIAL OF LOW-DOSE ASPIRIN FOR THE PREVENTION AND TREATMENT OF PREECLAMPSIA AMONG 9364 PREGNANT-WOMEN. LANCET, 343(8898), 619-629. DOI WoS348 Europe PMC46

Books

Year Citation
2009 Hodge, S. (2009). Lung Macrophages in health and disease.
DOI

Year	Citation
2009	Hodge, S. (2009). Lung Macrophages in health and disease. DOI

Book Chapters

Year	Citation
2018	Hodge, G., & Hodge, S. (2018). Steroid resistant CD8⁺CD28null NKT-like pro-inflammatory cytotoxic cells in chronic obstructive pulmonary disease. In F. A. Arosa (Ed.), On the Origin and Function of Human NK-like CD8+ T Cells: Charting New Territories (pp. 67-73). Frontiers Media SA. DOI
2015	Hodge, S., & Hodge, G. (2015). Evasion of cytotoxic lymphocyte and pulmonary macrophage mediated immune responses in lung cancer. In Ed B Bonavida (Ed.), Resistance of Targeted Anti-Cancer Therapeutics. Springer.
2011	Hodge, G., Hodge, S., Reynolds, P., & Holmes, M. (2011). Measurement of intracellular cytokines to improve therapeutic monitoring of immunosuppressive drugs following lung transplantation. In Lung Transplantation: Therapies, Complications and Outcomes (pp. 177-211).
2011	Hodge, G., Hodge, S., Reynolds, P., Chambers, D., & Holmes, M. (2011). Leucocyte intracellular cytokines in lung transplant patients - A more physiological indicator of immunosuppression than plasma drug levels. In Lung Transplantation: Therapies, Complications and Outcomes (pp. 147-176).
2009	hodge, S. (2009). Book Forward. In S. J. Hodge (Ed.), Lung Macrophages in Health and Disease. Bentham Science Publishers.
2009	hodge, S. (2009). Book Forward. In S. J. Hodge (Ed.), Lung Macrophages in Health and Disease. Bentham Science Publishers.
2009	Hodge, S. J. (2009). Leucocyte intracellular cytokines in lung transplant patients- a more physiological indicator of immunosuppression than plasma drug levels. In C. taylor (Ed.), Immunosuppression: New Research (pp. 91-115).
2009	Hodge, S. J. (2009). Defective clearance of apoptotic cells (efferocytosis). In S. J. Hodge (Ed.), Lung Macrophages in Health and Chronic Disease. Bentham.
2009	Hodge, S. J. (2009). Defective clearance of apoptotic cells (efferocytosis). In S. J. Hodge (Ed.), Lung Macrophages in Health and Chronic Disease. Bentham.
2009	Hodge, S. (2009). Defective clearance of apoptotic cells (efferocytosis) in chronic lung diseases. In Lung Macrophages in Health and Disease (pp. 62-75). DOI
2009	Reynolds, P., & Hodge, S. (2009). The impact of defective clearance of apoptotic cells in the pathogenesis of chronic lung diseases: chronic obstructive pulmonary disease, asthma and cystic fibrosis. In D. V. Krysko, & P. Vandenabeele (Eds.), Phagocytosis of Dying Cells: From Molecular Mechanisms to Human Disease (pp. 393-408). The Netherlands: Springer. DOI Scopus2
2008	Hodge, S. J. (2008). New Apoptosis Research in Respiratory Disease. In R. fenton (Ed.), Cell Apoptosis Research Progress. Nova Science Publishers.
2007	Hodge, G., Hodge, S., Reynolds, P., & Holmes, M. (2007). Measurement of Intracellular Cytokines to improve Therapeutic Monitoring of Immunosuppressive Drugs following Lung Transplantation. In O. N. Ulricker (Ed.), Transplantation Immunology Research Trends (pp. 111-146). New York: Nova Science Publishers.

Conference Papers

Year	Citation
2018	Ween, M., Whittall, J., Tran, H., & Hodge, S. (2018). Investigation of Cigarette Smoke Oxidised Lipids on Macrophages. In AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Vol. 197 (pp. 1 page). San Diego, CA: AMER THORACIC SOC.
2017	Hodge, G., Hodge, S., Holmes-Liew, C., Reynolds, P., & Holmes, M. (2017). Histone deacetylase 2 is decreased in peripheral blood pro-inflammatory CD8+ T and NKT-like lymphocytes following lung transplant. In Respirology Vol. 22 (pp. 394-400). Australia: WILEY-BLACKWELL. DOI Scopus4 WoS3 Europe PMC3
2015	Simpson, J., Yang, I., Upham, J., Reynolds, P., Hodge, S., James, A., . . . Gibson, P. (2015). Sputum And Serum Periostin Levels Are Associated With, But Do Not Predict Sputum Eosinophil Proportion In Severe Asthma. In AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Vol. 191 (pp. 1 page). Denver, CO: AMER THORACIC SOC. WoS1
2011	Hodge, S., Dean, M., Hodge, G., Holmes, M., & Reynolds, P. (2011). Decreased Efferocytosis (Phagocytosis of Apoptotic Cells) and Mannose Binding Lectin in the Airways of Patients with Bronchiolitis Obliterans Syndrome. In JOURNAL OF HEART AND LUNG TRANSPLANTATION Vol. 30 (pp. S119). San Diego, CA: ELSEVIER SCIENCE INC. DOI
2011	Hodge, G., Hodge, S., Chambers, D., Hopkins, P., Reynolds, P., Holmes, M., & Liew, C. -L. (2011). BOS Is Associated with Increased Expression of C4d on Airway Bronchial Epithelial Cells Using Flow Cytometry - Potential Use in Diagnosing AMR. In JOURNAL OF HEART AND LUNG TRANSPLANTATION Vol. 30 (pp. S56-S57). San Diego, CA: ELSEVIER SCIENCE INC. DOI
2010	Chambers, D., Hodge, S., Hodge, G., Kermeen, F., Reynolds, P., Holmes, M., & Hopkins, P. (2010). A Novel Approach to the Assessment of Lymphocytic Bronchiolitis - The 'B Score'. In JOURNAL OF HEART AND LUNG TRANSPLANTATION Vol. 29 (pp. S102). Chicago, IL: ELSEVIER SCIENCE INC. DOI
2010	Liew, C. -L., Hodge, G., Hodge, S., Chambers, D., Hopkins, P., Reynolds, P., & Holmes, M. (2010). Lymphocytic Bronchiolitis Is Associated with Inadequate Suppression of Blood T-Cell Granzyme B, IFN gamma and TNF alpha. In JOURNAL OF HEART AND LUNG TRANSPLANTATION Vol. 29 (pp. S101). Chicago, IL: ELSEVIER SCIENCE INC. DOI
2009	Hodge, S., Hodge, G., Ahern, J., Nairn, J., Liew, C. -L., Reynolds, P., . . . Holmes, M. (2009). Increased Levels of T-Cell Granzyme b in Bronchiolitis Obliterans Syndrome (BOS) Are Not Adequately Suppressed by Current Immunosuppressive Regimens. In JOURNAL OF HEART AND LUNG TRANSPLANTATION Vol. 28 (pp. S172). Paris, FRANCE: ELSEVIER SCIENCE INC. DOI
2009	Chambers, D., Hopkins, P., Kermeen, F., Abern, J., Hodge, G., Reynolds, P., . . . Hodge, S. (2009). Mucosal Integrin Expressing CD8 Lymphocytes infiltrate Small Airways during Episodes of Acute Lung Allograft Rejection - Link between Rejection and BOS?. In JOURNAL OF HEART AND LUNG TRANSPLANTATION Vol. 28 (pp. S138-S139). Paris, FRANCE: ELSEVIER SCIENCE INC. DOI
2008	Hodge, S., Holmes, M., Banerjee, B., Waterer, G., Reynolds, P., Hodge, G., & Cbambers, D. (2008). Epithelial to mesenchymal transition (EMT) as an indicator of airway wall remodelling in lung transplant patients. In JOURNAL OF HEART AND LUNG TRANSPLANTATION Vol. 27 (pp. S250). Boston, MA: ELSEVIER SCIENCE INC. DOI
2005	Hodge, S., Hodge, G., Jersmann, H., Holmes, M., & Reynolds, P. (2005). Azithromycin increases phagocytosis of apoptotic airway epithelial cells by alveolar macrophages in vitro. In European Respiratory Journal Vol. 26 (pp. 20s). Copenhagen, Denmark: European Respiratory Society.
2004	Hodge, G., Hodge, S., Haslam, R., McPhee, A., Sepulveda, H., Morgan, E., . . . Zola, H. (2004). Rapid detection of neonatal sepsis by simultaneous measurment of multiple cytokines using 100 mu L sample volumes. In CYTOMETRY PART A Vol. 59A (pp. 108-109). Montpellier, FRANCE: WILEY-LISS.
2004	Finan, K., Hodge, G., Reynolds, A., Hodge, S., Holmes, M., Baker, A., & Reynolds, P. (2004). Delivery of tissue inhibitor of metalloproteinase 3 inhibits growth of lung cancer tumours in vivo. In MOLECULAR THERAPY Vol. 9 (pp. S364). Minneapolis, MN: ACADEMIC PRESS INC ELSEVIER SCIENCE.
2003	Finan, K., Hodge, G., Reynolds, A., Hodge, S., Holmes, M., Baker, A., & Reynolds, P. (2003). Over-expression of TIMP 3 causes apoptosis in lung cancer cells. In JOURNAL OF GENE MEDICINE Vol. 5 (pp. S18). QUEENSLAND INST MED RES BRISBANE, BRISBANE, AUSTRALIA: JOHN WILEY & SONS LTD.
2003	Finan, K., Hodge, G., Reynolds, A., Hodge, S., Holmes, M., Baker, A., & Reynolds, P. (2003). Over-expression of TIMP-3 causes apoptosis in lung cancer cells. In MOLECULAR THERAPY Vol. 7 (pp. S287). WASHINGTON, D.C.: ACADEMIC PRESS INC ELSEVIER SCIENCE.

Conference Items

Year	Citation
2018	Hodge, G., Hodge, S., Nguyen, P., Yeo, A., Sarkar, P., Badiei, A., . . . Holmes, M. (2018). Bronchiolitis obliterans syndrome is associated with increased p-glycoprotein expression and loss of glucocorticoid receptor from steroid resistant pro-inflammatory CD8+T cells. Poster session presented at the meeting of Abstracts of the 22nd Congress of the Asian Pacific Society of Respirology, as published in Respirology. Sydney, Australia: Wiley-Blackwell. DOI
2017	Gibson, P., Yang, I., Upham, J., Reynolds, P., Hodge, S., James, A., . . . Simpson, J. (2017). Azithromycin reduces exacerbations in adults with persistent symptomatic eosinophilic asthma. Poster session presented at the meeting of TSANZ oral presentations, as published in Respirology. Canberra, ACT: Wiley. WoS1
2017	Powell, H., Simpson, J., Yang, I., Upham, J., Reynolds, P., Hodge, S., . . . Gibson, P. (2017). An analysis of the effect of azithromycin in persistent asthma, based on pre-specified asthma phenotypes. Poster session presented at the meeting of TSANZ poster presentations, as published in Respirology. Canberra, ACT: Wiley.
2017	Hodge, G., Hodge, S., Yeo, A., Phan, N., Hopkins, E., Holmes-Liew, C. -L., . . . Holmes, M. (2017). REDUCED GCR, HDAC2 AND HSP90 IN PRO-INFLAMMATORY LYMPHOCYTES IN THE SMALL AIRWAYS DURING BOS. Poster session presented at the meeting of RESPIROLOGY. WILEY.
2017	Hodge, G., Jersmann, H., Holmes, M., Reynolds, P., & Hodge, S. (2017). Steroid resistant CD8+CD28(null) NKT-like pro-inflammatory cytotoxic cells in COPD. Poster session presented at the meeting of Proceedings of The Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ)Annual Scientific Meeting, 2017, as published in Respirology. Canberra, ACT: Wiley.
2017	Roscioli, E., Bac-Tran, H., Jersmann, H., Hodge, G., Hopkins, E., Hamon, R., . . . Hodge, S. (2017). Zinc dyshomeostasis and autophagy as critical determinants for airway epithelial dysfunction in COPD. Poster session presented at the meeting of Proceedings of The Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ)Annual Scientific Meeting, 2017, as published in Respirology. Canberra, ACT: Wiley.
2017	Ween, M., Jones, C., Tran, H., Whittall, J., & Hodge, S. (2017). Investigation of the CD1b lipid antigen presentation pathway In pulmonary COPD. Poster session presented at the meeting of Abstracts of The Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ) Annual Scientific Meeting 2017, as published in Respirology. Canberra, Australia: Wiley. DOI
2017	Whittall, J., Ween, M., & Hodge, S. (2017). Innate immune macrophage response to NTHi and azithromycin in COPD. Poster session presented at the meeting of Abstracts of The Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ) Annual Scientific Meeting 2017, as published in Respirology. Canberra, Australia: Wiley. DOI
2017	Ween, M., Whittall, J., & Hodge, S. (2017). E-CIGARETTES CAUSE INCREASED CELL DEATH, APOPTOSIS AND ALTERED CYTOKINE PROFILE OF HUMAN BRONCHIAL EPITHELIAL CELLS. Poster session presented at the meeting of RESPIROLOGY. WILEY.
2017	Tran, H. B., Hamon, R., Truong, T. T., Ween, M., Riscioli, E., Jerssman, H., . . . Hodge, S. (2017). CIGARETTE SMOKE-INDUCED INFLAMMATION IN MACROPHAGES IS INITIATED BY NLRP3/AIM2 INFLAMMASOMES: INVOLVEMENT OF THE SPHINGOSINE-1-PHOSPHATE (S1P) SIGNALLING. Poster session presented at the meeting of RESPIROLOGY. WILEY.
2017	Hamon, R., Hai, T., Roscioli, E., Jersmann, H., Reynolds, P., Wilbert, S., & Hodge, S. (2017). Non-antibiotic macrolides restore airway macrophage phagocytic function with potential anti-inflammatory effects in chronic lung diseases. Poster session presented at the meeting of Proceedings of The Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ)Annual Scientific Meeting, 2017, as published in Respirology. Canberra, ACT: Wiley.
2016	Tran, H., Rhys, H., Ween, M., Hodge, G., Barnawi, J., Reynolds, P., . . . Hodge, S. (2016). SPNS2 IN THE AIRWAY EPITHELIAL CELLS AND ALVEOLAR MACROPHAGES CONTRIBUTES DIFFERENTLY INTO CIGARETTE-NDUCED DEREGULATED S1P SIGNALING: A TRANSLATION TO THE MECHANISM OF COPD. Poster session presented at the meeting of RESPIROLOGY. WILEY-BLACKWELL.
2016	Tran, H., Barnawi, J., Ween, M., Hamon, R., Roscioli, E., Hodge, G., . . . Hodge, S. (2016). CHANGED INTRACELLULAR LOCALIZATION OF SPHINGOSINE KINASES BY CIGARETTE SMOKE IN MACROPHAGES MAY CONTRIBUTE TO DEFECTIVE PHAGOCYTIC FUNCTION. Poster session presented at the meeting of RESPIROLOGY. WILEY-BLACKWELL.
2016	Tran, H., Hamon, R., Ween, M., Hodge, G., Roscioli, E., Barnawi, J., . . . Hodge, S. (2016). DIFFERENTIAL SUBCELLULAR LOCALIZATION AND EXPRESSION OF SPINSTER HOMOLOG 2 (DROSOPHILA) IN AIRWAY EPITHELIAL CELLS AND MACROPHAGES IN RESPONSE TO CIGARETTE SMOKE AND IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE MAY CONTRIBUTE TO MACROPHAGE PHAGOCYTIC DYSFUNCTION. Poster session presented at the meeting of RESPIROLOGY. WILEY-BLACKWELL.
2016	Hodge, G., Hodge, S., Yeo, A., Nguyen, P., Hopkins, E., Holmes-Liew, C., . . . Holmes, M. (2016). BOS is associated with increased cytotoxic pro-inflammatory CD8 T and NKT-Like and NK cells in the distal airways. Poster session presented at the meeting of Abstracts of the 36th Annual Meeting and Scientific Sessions of the International Society for Heart and Lung Transplantation (ISHLT), as published in Journal of Heart and Lung Transplantation. Washington, DC: Elsevier. DOI
2016	Roscioli, E., Bac-Tran, H., Hamon, R., Zalewski, P., Hodge, G., Reynolds, P., & Hodge, S. (2016). AUTOPHAGY-RELATED EPITHELIAL DISINTEGRATION IN AN EX VIVO MODEL OF COPD. Poster session presented at the meeting of RESPIROLOGY. WILEY-BLACKWELL.
2016	Ween, M., Hodge, G., Reynolds, P., & Hodge, S. (2016). The new kid on the block: e-cigarettes can cause damage to airway cells and cause airway macrophage dysfunction. Poster session presented at the meeting of Abstracts of the Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science 2016 Annual Scientific Meetings, as published in Respirology. Perth, Western Australia: Wiley. DOI
2016	Hodge, G., Roscioli, E., Jersmann, H., Tran, H., Holmes, M., Reynolds, P., & Hodge, S. (2016). Steroid resistance in COPD is associated with impaired molecular chaperone Hsp90 expression by pro-inflammatory lymphocytes. Poster session presented at the meeting of Respiratory Research. WILEY-BLACKWELL. DOI Scopus8
2016	Hamon, R., Roscioli, E., Jersmann, H., & Hodge, S. (2016). BUSHFIRE SMOKE AND ITS EFFECTS ON AIRWAY CELLS. Poster session presented at the meeting of RESPIROLOGY. WILEY-BLACKWELL.
2016	Tran, H., Hamon, R., Roscioli, E., Ween, M., Hodge, G., Jersmann, H., . . . Hodge, S. (2016). CIGARETTE SMOKE INDUCED MULTIPLE INFLAMMASOME ACTIVATION AND ANTI-INFLAMMATORY EFFECTS OF S1P AND FTY720 SUGGEST NOVEL TARGETS IN COPD. Poster session presented at the meeting of RESPIROLOGY. WILEY-BLACKWELL.
2016	Roscioli, E., Bac-Tran, H., Hamon, R., Zalewski, P., & Hodge, S. (2016). Association Of Increased Autophagy In COPD And Dysregulation Of Zinc Handling Systems. Poster session presented at the meeting of AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. San Francisco, CA: AMER THORACIC SOC.
2016	Rogers, G., Leong, L., Gibson, P., Yang, I., Hodge, S., Reynolds, P., . . . Simpsons, J. (2016). The Lung Microbiota In Stable Adult Asthma Differs According To Inflammatory Phenotype, Sex, And Atopy. Poster session presented at the meeting of AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. San Francisco, CA: AMER THORACIC SOC.
2016	Ween, M., Hodge, G., Reynolds, P., & Hodge, S. (2016). The new kid on the block: e-cigarettes can cause damage to airway cells and cause airway macrophage dysfunction. Poster session presented at the meeting of Abstract of the 2016 International Conference of the American Thoracic Society, as published in American Journal of Respiratory and Critical Care Medicine. San Francisco, CA: American Thoracic Society. WoS1
2016	Leong, L., Rogers, G., Gibson, P., Yang, I., Reynolds, P., Hodge, S., . . . Simpson, J. (2016). THE LUNG MICROBIOTA IN STABLE ADULT ASTHMA DIFFERS ACCORDING TO INFLAMMATORY PHENOTYPE. Poster session presented at the meeting of RESPIROLOGY. WILEY-BLACKWELL.
2016	Simpson, J., Powell, H., Yang, I., Upham, J., Reynolds, P., Hodge, S., . . . Gibson, P. (2016). SPUTUM INFLAMMATORY PHENOTYPES IN SYMPTOMATIC ASTHMA AROUND AUSTRALIA. Poster session presented at the meeting of RESPIROLOGY. WILEY-BLACKWELL.
2016	Hodge, G., Hodge, S., Yeo, A., Nguyen, P., Hopkins, E., Holmes-Liew, C., . . . Holmes, M. (2016). BOS is associated with increased cytotoxic pro-inflammatory CD8 T and NKT-Like and NK cells in the distal airways. Poster session presented at the meeting of Abstracts of the Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science, Annual Scientific Meeting, as published in Respirology. Perth, WA: Wiley-Blackwell. DOI
2015	Upham, J., Chen, A., Carroll, M., Petsky, H., Pizzutto, S., Yerkovich, S., . . . Chang, A. (2015). IMMUNE RESPONSES TO NONTYPEABLE HAEMOPHILUS INFLUENZAE IN PROTRACTED BACTERIAL BRONCHITIS. Poster session presented at the meeting of RESPIROLOGY. Queensland, AUSTRALIA: WILEY-BLACKWELL. WoS1
2015	Hodge, G., Hodge, S., Holmes-Liew, C., Reynolds, P., & Holmes, M. (2015). HISTONE DEACETYLASE 2 IS DECREASED IN PERIPHERAL BLOOD CYTOTOXIC/PRO-INFLAMMATORY CD8+T AND NKT-LIKE LYMPHOCYTES FOLLOWING LUNG TRANSPLANT. Poster session presented at the meeting of RESPIROLOGY. Queensland, AUSTRALIA: WILEY-BLACKWELL.
2015	Hodge, G., Jersmann, H., Holmes, M., Reynolds, P., & Hodge, S. (2015). LYMPHOCYTE SENESCENCE IN COPD IS ASSOCIATED WITH DECREASED HISTONE DEACETYLASE 2 EXPRESSION BY PRO-INFLAMMATORY LYMPHOCYTES. Poster session presented at the meeting of RESPIROLOGY. Queensland, AUSTRALIA: WILEY-BLACKWELL.
2015	Barnawi, J., Jersmann, H., Tran, H., Pitson, S., Haberberger, R., Meech, R., & Hodge, S. (2015). DIFFERENTIAL DNA METHYLATION PATTERN OF SPHINGOSINE-1 PHOSPHATE RECEPTOR 5 IN ALVEOLAR MACROPHAGES IN COPD - POTENTIAL LINK TO FAILED EFFEROCYTOSIS?. Poster session presented at the meeting of RESPIROLOGY. Queensland, AUSTRALIA: WILEY-BLACKWELL.
2015	Tran, H., Zalewski, P., Roscioli, E., Barnawi, J., Hodge, G., Reynolds, P., & Hodge, S. (2015). ZINC DYSHOMEOSTASIS IS LINKED TO DEFECTIVE LUNG MACROPHAGE PHAGOCYTIC FUNCTION AND AIRWAY INFLAMMATION IN MICE EXPOSED TO CIGARETTE SMOKE. Poster session presented at the meeting of RESPIROLOGY. Queensland, AUSTRALIA: WILEY-BLACKWELL.
2015	Roscioli, E., Tran, H., Zalewski, P., Hodge, G., Carrol, A., Rix, S., . . . Hodge, S. (2015). ZINC HANDLING SYSTEM AND AUTOPHAGY IN COPD. Poster session presented at the meeting of RESPIROLOGY. Queensland, AUSTRALIA: WILEY-BLACKWELL.
2015	Roscioli, E., Hamon, R., Ruffin, R., Zalewski, P., Hodge, S., Grant, J., & Lester, S. (2015). BIRC2 SINGLE NUCLEOTIDE POLYMORPHISMS MODULATE THE SEVERITY OF ASTHMA IN A CAUCASIAN COMMUNITY-BASED COHORT. Poster session presented at the meeting of RESPIROLOGY. Queensland, AUSTRALIA: WILEY-BLACKWELL.
2015	Carroll, A., Rix, S., Tran, H., Barnawi, J., Hodge, G., Pitson, S., . . . Hodge, S. (2015). PULMONARY MACROPHAGE EFFEROCYTOSIS IN COPD IS SUPPRESSED BY DISTURBANCES TO FEEDBACK MECHANISMS IN SPHINGOSINE 1 PHOSPHATE SIGNALLING AND REVERSED WITH FTY720. Poster session presented at the meeting of RESPIROLOGY. Queensland, AUSTRALIA: WILEY-BLACKWELL.
2015	Carroll, A., Rix, S., Ahern, J., Hodge, G., Pizzuto, S., Jersmann, H., . . . Hodge, S. (2015). A SMALL VOLUME TECHNIQUE TO EXAMINE AND COMPARE ALVEOLAR MACROPHAGE PHAGOCYTOSIS OF APOPTOTIC CELLS AND NTHI. Poster session presented at the meeting of RESPIROLOGY. Queensland, AUSTRALIA: WILEY-BLACKWELL.
2014	Tran, H., Ahern, J., Hodge, G., Holt, P., Dean, M., Reynolds, P., & Hodge, S. (2014). OXIDATIVE CHANGES TO SUB-CELLULAR LOCALIZATION AND FUNCTION OF MANNOSE BINDING LECTIN ON ALVEOLAR MACROPHAGES MAY CONTRIBUTE TO THEIR DECREASED PHAGOCYTIC FUNCTION AND INCREASED INFLAMMATION IN COPD. Poster session presented at the meeting of RESPIROLOGY. WILEY-BLACKWELL.
2014	Hodge, G., Barnawi, J., Holmes, M., Jersmann, H., Reynolds, P., & Hodge, S. (2014). LUNG CANCER IS ASSOCIATED WITH DECREASED EXPRESSION OF PERFORIN, GRANZYME B AND IFNG BY INFILTRATING T CELLS, NKT-LIKE AND NK CELLS. Poster session presented at the meeting of RESPIROLOGY. WILEY-BLACKWELL 111 RIVER ST, HOBOKEN 07030-5774, NJ USA: WILEY-BLACKWELL. WoS1
2014	Barnawi, J., Holt, P., Hodge, G., Jersmann, H., Pitson, S., Haberberger, R., & Hodge, S. (2014). THERAPEUTIC MODULATION OF THE SPHINGOSINE SIGNALLING SYSTEM WITH THYMOQUININE AS A NOVEL MACROPHAGE-TARGETED TREATMENT FOR COPD. Poster session presented at the meeting of Respirology. WILEY-BLACKWELL 111 RIVER ST, HOBOKEN 07030-5774, NJ USA: Wiley. DOI
2014	Hodge, G., Jersmann, H., Holmes, M., Reynolds, P., & Hodge, S. (2014). LYMPHOCYTE SENESCENCE IN COPD IS ASSOCIATED WITH LOSS OF GLUCOCORTICOID RECEPTOR EXPRESSION BY PRO-INFLAMMATORY/CYTOTOXIC LYMPHOCYTES. Poster session presented at the meeting of RESPIROLOGY. WILEY-BLACKWELL.
2014	Simpson, J., Gao, P., Baines, K., Yang, I., Reynolds, P., Hodge, S., . . . Gibson, P. (2014). GALECTIN 3 AND GALECTIN 3 BINDING PROTEIN IN ASTHMA INFLAMMATORY SUBTYPES. Poster session presented at the meeting of RESPIROLOGY. WILEY-BLACKWELL.
2014	Hodge, G., Upham, J., Chang, A., Gibson, P., Pizzutto, S., Petsky, H., & Hodge, S. (2014). INCREASED PERIPHERAL BLOOD PRO-INFLAMMATORY/CYTOTOXIC T AND NKT-LIKE CELLS IN INDIGENOUS CHILDREN WITH BRONCHIECTASIS. Poster session presented at the meeting of RESPIROLOGY. WILEY-BLACKWELL.
2014	Simpson, J., Carroll, M., Gibson, P., Yang, I., Reynolds, P., Hodge, S., . . . Peters, M. (2014). REDUCED ANTI-VIRAL INNATE IMMUNITY IN PATIENTS WITH SEVERE ASTHMA IS ASSOCIATED WITH NEUTROPHILIC INFLAMMATION AND HIGH DOSE INHALED STEROIDS. Poster session presented at the meeting of RESPIROLOGY. WILEY-BLACKWELL.
2014	Hodge, S., Hodge, G., Pizzutto, S., Petsky, H., Gibson, P., Chang, A., & Upham, J. (2014). REDUCED MACROPHAGE PHAGOCYTIC HOST RESPONSE TO NTHI IN CHILDREN WITH BRONCHIECTASIS. Poster session presented at the meeting of RESPIROLOGY. WILEY-BLACKWELL. WoS2
2013	Ahern, J., Mukaro, V., Hodge, G., Reynolds, P., Dean, M., Pizzutto, S., & Hodge, S. (2013). Oxidative Stress Decreases Functional Airway Mannose Binding Lectin In COPD. Poster session presented at the meeting of AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. AMER THORACIC SOC.
2013	Ahern, J., Mukaro, V., Hodge, G., Dean, M., Weiland, F., Pizzutto, S., . . . Hodge, S. (2013). Oxidative stress decreases functional airway mannose binding lectin in COPD. Poster session presented at the meeting of Abstracts of the Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science 2013 Annual Scientific Meetings, as published in Respirology. Darwin, N.T.: Wiley-Blackwell. DOI
2013	Barnawi, J., Ahern, J., Jersmann, H., Haberberger, R., & Hodge, S. (2013). CHARACTERIZATION OF THE SPHK/S1P PATHWAY IN HUMAN ALVEOLAR MACROPHAGES IN COPD AND LUNG CANCER. Poster session presented at the meeting of RESPIROLOGY. WILEY-BLACKWELL.
2013	Powell, H., Garside, C. G., Simpson, J. L., Yang, I. A., Reynolds, P. N., Hodge, S. J., . . . AMAZES Study Research Group. (2013). Characteristics of uncontrolled asthma in Australia. Poster session presented at the meeting of Abstracts of the Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science 2013 Annual Scientific Meetings, as published in Respirology. Darwin, N.T.: Wiley-Blackwell. DOI
2013	Hodge, G., Jersmann, H., Ahern, J., Holmes, M., Reynolds, P., & Hodge, S. (2013). COPD IS ASSOCIATED WITH INCREASED PGP-1 EXPRESSION IN PRO-INFLAMMATORY PERIPHERAL BLOOD T, NK AND NKT-LIKE CELLS. Poster session presented at the meeting of RESPIROLOGY. WILEY-BLACKWELL.
2013	Hodge, G., Hodge, S., Ahern, J., Holmes-Liew, C. -L., Reynolds, P., & Holmes, M. (2013). Targeting Steroid Resistant Peripheral Blood Pro-Inflammatory CD28null T Cells by Inhibiting CD137 Expression: Relevance to BOS. Poster session presented at the meeting of JOURNAL OF HEART AND LUNG TRANSPLANTATION. Montreal, CANADA: ELSEVIER SCIENCE INC. DOI WoS1
2013	Simpson, J. L., Yang, I. A., Reynolds, P. N., Hodge, S. J., James, A. L., Upham, J., . . . AMAZES Study. (2013). Alternatives to induced sputum for identifying patients with eosinophilic asthma. Poster session presented at the meeting of Abstracts of the Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science 2013 Annual Scientific Meetings, as published in Respirology. Darwin, N.T.: Wiley-Blackwell. DOI
2013	Hodge, G., Hodge, S., Ahern, J., Holmes-Liew, C. -L., Reynolds, P., & Holmes, M. (2013). TARGETING STEROID-RESISTANT PERIPHERAL BLOOD PRO-INFLAMMATORY CD28NULL T CELLS BY INHIBITING CD137 EXPRESSION: RELEVANCE TO TREATMENT OF BOS. Poster session presented at the meeting of RESPIROLOGY. WILEY-BLACKWELL.
2013	Hodge, G., Jersmann, H., Ahern, J., Holmes, M., Reynolds, P., & Hodge, S. (2013). COPD Is Associated With Increased Pgp-1 Expression In Pro-Inflammatory Peripheral Blood T, Nk And Nkt-Like Cells. Poster session presented at the meeting of AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. AMER THORACIC SOC.
2012	Hodge, S., Hodge, G., Holmes-Liew, C. -L., Reynolds, P., & Holmes, M. (2012). BOS Is Associated with Increased Peripheral Blood NKT-Like and NK Cell Granzymes, Perforin and Th1 Pro-Inflammatory Cytokines. Poster session presented at the meeting of JOURNAL OF HEART AND LUNG TRANSPLANTATION. Prague, CZECH REPUBLIC: ELSEVIER SCIENCE INC. DOI
2012	Hodge, G., Hodge, S., Holmes-Liew, C. -L., Reynolds, P., & Holmes, M. (2012). Down-Regulation of CD28 and Up-Regulation of 4-1BB on Peripheral Blood Pro-Inflammatory CD8+T Cells Is Associated with BOS. Poster session presented at the meeting of JOURNAL OF HEART AND LUNG TRANSPLANTATION. Prague, CZECH REPUBLIC: ELSEVIER SCIENCE INC. DOI
2012	Hodge, G., Hodge, S., Ahern, J., Holmes-Liew, C. -L., Reynolds, P., & Holmes, M. (2012). BOS IS ASSOCIATED WITH AN INCREASE IN GRANZYMES/PERFORIN AND PRO-INFLAMMATORY CYTOKINES BY PERIPHERAL BLOOD NK CELLS. Poster session presented at the meeting of RESPIROLOGY. WILEY-BLACKWELL.
2012	Garside, C., Simpson, J., Yang, I., Reynolds, P., Hodge, S., James, A., . . . Gibson, P. (2012). INFLAMMATORY SUBTYPES OF UNCONTROLLED ASTHMA IN AUSTRALIA. Poster session presented at the meeting of RESPIROLOGY. WILEY-BLACKWELL.
2012	Ahern, J., Hodge, G., Jersmann, H., Holmes, M., Reynolds, P. N., Upham, J., & Hodge, S. (2012). SOLUBLE RECEPTOR FOR ADVANCED GLYCATION END-PRODUCTS IS DECREASED IN HEALTHY SMOKERS AND CURRENT SMOKER COPD SUBJECTS. Poster session presented at the meeting of RESPIROLOGY. WILEY-BLACKWELL.
2012	Mukaro, V., Hodge, G., Holmes, M., Reynolds, P., & Hodge, S. (2012). ENHANCED CYTOTOXIC FUNCTION OF NK AND NKT-LIKE CELLS ASSOCIATED WITH DECREASED CD94 IN THE AIRWAY IN COPD. Poster session presented at the meeting of RESPIROLOGY. WILEY-BLACKWELL.
2012	Hodge, G., Hodge, S., Holmes-Liew, C. -L., Reynolds, P. N., & Holmes, M. (2012). DOWNREGULATION OF CD28 AND UPREGULATION OF 4-1BB ON PERIPHERAL BLOOD PRO-INFLAMMATORY CD8+T CELLS IS ASSOCIATED WITH BOS. Poster session presented at the meeting of RESPIROLOGY. WILEY-BLACKWELL.
2009	Hodge, S., Matthews, G., Ahern, J., Djukic, M., Hodge, G., Jersmann, H., . . . Reynolds, P. (2009). Is There a Therapeutic Role for Mannose Binding Lectin in Cigarette Smoke-Induced Lung Inflammation? Evidence from a Murine Model.. Poster session presented at the meeting of AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. AMER THORACIC SOC.

Grants & Funding

Total funding for career $15,980,192 [$750,500.00 relinquished]

Current Funding: NHMRC

2013-2016	NHMRC CAREER DEVELOPMENT FELLOWSHIP R.D. Wright Biomedical CDF Level 2 APP1045511	Investigating the causes of failed efferocytosis in COPD/emphysema with a view to identifying novel therapeutic targets.	Hodge S	$439,920
2016-2018	NHMRC PROJECT GRANT	Exploiting increased autophagy in bronchial epithelial cells: a new therapeutic approach for chronic obstructive pulmonary disease (COPD).	Hodge S, Zalewski P, Roscioli E.	$724,161
2016-2018	NHMRC PROJECT GRANT	Targeting the defective airway macrophage function in chronic obstructive pulmonary disease (COPD): a new therapeutic approach.	Hodge S, Reynolds PN.	$710,928
2016-	NHRMC PROJECT GRANT	Conquering the final frontier in lung transplantation - Mesenchymal stromal cell therapy for chronic lung allograft dysfunction.	Chambers D, Hopkins P, Glanville A, Westall G, Holmes M. Hodge S (AI)	$1,887,790.
2014-2018	NHMRC CRE APP1058550	Phenotyping severe asthma for improved outcomes: a translational CRE.	Gibson, Marks, McDonald, Wark, Upham, Thien, James, Reddell, King, Smith, Hodge S (AI)	$2,499,750
2013-2016	NHMRC Project Grant 1042601	Protracted bacterial bronchitis: long term outcomes, systemic and airway predictors of recurrence	Chang A, Upham J, Gibson P, Yerkovich S, Baines K, Hodge S, Pizzutto S, Masters I, Buntain H.	$777,376.76

Current funding- non-NHMRC

2016	Channel 7 Children’s Research Foundation		Hodge S, Chang A, Upham J	$75,000
2013-2017	Royal Adelaide Hospital CCF Brine Bequest	Mannose binding lectin as a novel therapy to prevent COPD/emphysema in smokers.	Hodge S	$300,000
2016	TSANZ and National Asthma Council Australia	Are e-cigarettes as harmless as sellers would have you believe? Investigating the effect of Vaping on macrophage function.	Ween M, Hodge S	$60,000
2016-2017	Astra Zeneca/ Thoracic Society of Australia and New Zealand Respiratory Research fellowship		Roscioli E, Hodge S (Supervisor)	$150000
2016	RAH Clinical Project Grant	The role of autophagy in airway epithelial cells exposed to bush fire smoke	Roscioli E, Hodge S, Jersmann H.	$50,000
2016	RAH Clinical Project Grant	Are e-cigarettes as harmless as sellers would have you believe? Investigating the effect of Vaping on macrophage function.	Ween M, Hodge S.	$50,000
2016	Asthma Australia Travel Award for mid-career researchers		Tran H, Hodge S (supervisor)	$5000
2016	RIBG Funding		Hodge S.	$70,000
2016	RIBG Funding		Hodge G, Hodge S	$22,000

Previous funding: NHMRC

2013-2015	National Health and Medical Research Council of Australia Project Grant 1045514	Identification and therapeutic modulation of sphingolipids as novel lung macrophage-targeted treatments for COPD/emphysema	Hodge S, Haberberger R, Reynolds PN, Meech R.	$670,475.81
2010-2012	National Health and Medical Research Council of Australia Project Grant 627223	Alveolar macrophage zinc and zinc transporters and their role in phagocytosis	Zalewski P, Hodge S, Jersmann H.	$284,044.00
2010-2012	National Health and Medical Research Council of Australia Project Grant 626972	Modulation of macrophage function as a therapy for chronic obstructive pulmonary disease (COPD)	Hodge S, Reynolds P, Holmes M, Hodge G, Jersmann J.	$428,104.00
2009-2013	National Health and Medical Research Council of Australia Project Grant 569246	Asthma Macrolides Azithromycin Efficacy and Safety study.	PG Gibson, JL Simpson, J Upham, PR Reynolds, IA Yang, S Hodge, AL James.	$3,098,136.00
2009-2011	National Health and Medical Research Council of Australia Project Grant 565210	Surfactant protein D as a candidate therapy in COPD.	P Reynolds, S Hodge, H Clark.	$400,394.00
2008-2011	National Health and Medical Research Council of Australia Biomedical Career Development Award 508134	Investigating the causes of failed efferocytosis in COPD/emphysema with a view to identifying novel therapeutic targets.	S Hodge	$375,250.00
2008-2010	National Health and Medical Research Council of Australia Project Grant 508121	Monitoring of leukocyte cytokine /chemokine molecules to improve morbidity in lung transplant patients.	PN Reynolds, MD Holmes, G Hodge, S Hodge, D Chambers.	$371,604.00
2005-2007	National Health and Medical Research Council of Australia Project Grant 349337	The Role of Apoptosis and Macrophage Function in Chronic Obstructive Pulmonary Disease	P N. Reynolds, MD. Holmes, G Hodge, S Hodge	$463,400.00
2008-2011	National Health and Medical Research Council of Australia Clinical Career Development Award 508135 Relinquished for Biomedical Career Development Award.	Investigating the causes of failed efferocytosis in COPD/emphysema with a view to identifying novel therapeutic targets.	Sandra Hodge	$370,000.00
2008-2011	National Health and Medical Research Council of Australia Biomedical Career Development Award 508135	Investigating the causes of failed efferocytosis in COPD/emphysema with a view to identifying novel therapeutic targets.	Sandra Hodge	$370,000.00

Previous funding- non NHMRC

2015	RIBG Funding	Hodge G, Hodge S	$22,000
2015	Asthma Australia Travel Award for mid-career researchers	Hodge S	$5000
2014	RAH Clinical Project Grant	Hodge G, Hodge S	$35,000
2013-14	Lung Foundation Australia/ Boehringer Ingelheim COPD Research Fellowship		$160,000
2014	Menarini	Hodge G, Hodge S	$20,000
2013	Thoracic Society of Australia and New Zealand Robert Pierce Grant-in-Aid for Indigenous Lung Health.	Hodge S	$15,000
2013-2014	Channel 7 Children’s Research Foundation APP13688 Adaptive and innate immunity in children with bronchiectasis.	Chang A, Hodge S, Yerkovich S, Pizzutto S.	$75,000
2012	Royal Adelaide Hospital Clinical Research Grant. Reducing steroid resistance by targeting P-gp1 on pro-inflammatory T-cell subsets to reduce inflammation in COPD	Hodge G, Hodge S	$45,000

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Current Higher Degree by Research Supervision (University of Adelaide)

Date	Role	Research Topic	Program	Degree Type	Student Load	Student Name
2018	Principal Supervisor	Role of Lc3-associated Phagocytosis in COPD and Lung Cancer Patho-genesis	Doctor of Philosophy	Doctorate	Full Time	Mr Patrick Fordjour Asare

Past Higher Degree by Research Supervision (University of Adelaide)

Date	Role	Research Topic	Program	Degree Type	Student Load	Student Name
2011 - 2015	Principal Supervisor	Genetic and Epigenetic Characterization of the Sphingosine-1-Phosphate Signalling System in Macrophages in Chronic Obstructive Pulmonary Disease	Doctor of Philosophy	Doctorate	Full Time	Mr Jameel Barnawi
2004 - 2008	Co-Supervisor	Characterisation of Markers Associated with Systemic Inflammation in Children with Chronic Kidney Disease	Doctor of Philosophy	Doctorate	Part Time	Dr Judith Nairn

Other Supervision Activities

Date	Role	Research Topic	Location	Program	Supervision Type	Student Load	Student Name
2018 - ongoing	Principal Supervisor	Mechanistic and therapeutic studies of impaired phagocytic removal and xenophagic degradation of airway bacteria in COPD	The University of Adelaide	—	Doctorate	—	Patrick Asare
2018 - ongoing	Principal Supervisor	Assessing the role of SIRT-1 in airway macrophage dysfunction in COPD (and its association with the sphingosine-1-phosphate pathway)	The University of Adelaide	—	Honours	Full Time	Alarmelu Ram
2018 - 2018	Principal Supervisor	Investigating the capacity of azithromycin treatment to upregulate SIRT-1 expression and negate the airway macrophage dysfunction in COPD	The University of Adelaide	MBBS Elective	Other	Full Time	Charles Jones
2017 - ongoing	Other	Create Communicate Connect Program	The University of Adelaide	Create Communicate Connect Program	Other	—	n/a
2016 - 2017	Principal Supervisor	the immune molecule CD1b, and its potential role in the pathogenesis of COPD.	The University of Adelaide	—	Honours	Full Time	Charles Jones
2011 - 2011	External Supervisor	Expression profile of the sphingosine kinase signalling system in the lung of patients with chronic obstructive pulmonary disease	Flinders University	—	Honours	Full Time	Fabian Cordts
2010 - 2010	Principal Supervisor	Cytotoxic T-cell -mediated immune responses in patients with lung cancer and chronic obstructive pulmonary disease (COPD): implications for immune evasion by cancer cells	The University of Adelaide	—	Honours	Full Time	Cyd Soriano

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Board Memberships

Date	Role	Board name	Institution name	Country
2017 - ongoing	Director	The Thoracic Society of Australia and New Zealand Limited	The Thoracic Society of Australia and New Zealand	Australia
2017 - ongoing	Director	Board of the Thoracic Society of Australia and New Zealand Limited	—	—

Committee Memberships

Date	Role	Committee	Institution	Country
2015 - ongoing	Member	CAHLN RRC Clinical Project Grant Committee	—	—
2015 - ongoing	Member	RAH Research Foundation Research Infrastructure Block Grants Committee	—	—
2015 - ongoing	Chair	TSANZ Cell Biology and Immunology SIG	—	—
2015 - ongoing	Chair	Research Committee Awards Sub-committee, TSANZ	—	—
2013 - ongoing	Member	TSANZ Research sub-committee	—	—
2013 - ongoing	Member	SA Pathology/ Hanson Institute Research equipment Advisory Committee	—	—
2013 - 2016	Member	TSANZ Research sub-committee	—	—
2012 - ongoing	Member	Education and Research-subcommittee	Thoracic Society of ANZ	—
2012 - 2016	Member	NHMRC GRP	—	—

Memberships

Date	Role	Membership	Country
2015 - ongoing	—	Asia Pacific Society of Respirology	—
2012 - ongoing	—	International Society for Heart and Lung Transplantation	—
2012 - ongoing	—	European Respiratory Society	—
2012 - ongoing	—	American Thoracic Society	—
2010 - ongoing	—	Australian Lung Foundation	—
2005 - ongoing	—	Thoracic Society of Australia and New Zealand	—

Consulting/Advisories

Date	Institution	Department	Organisation Type	Country
2017 - ongoing	Thoracic Society of Australia and New Zealand	—	—	Australia
2017 - ongoing	Thoracic Society of Australia and New Zealand and the Lung Foundation Australia	—	—	Australia

Offices Held

Date	Office Name	Institution	Country
2017 - ongoing	Deputy Treasurer	The Thoracic Society of Australia and New Zealand	Australia
2017 - ongoing	Finance and Risk Assessment Committee	The Thoracic Society of Australia and New Zealand	Australia
2017 - ongoing	Co-chair Research Committee	The Thoracic Society of Australia and New Zealand	Australia

Position: Head Chronic Lung Disease Research Lab
Phone: 83137080
Email: sandra.hodge@adelaide.edu.au
Campus: North Terrace
Building: Adelaide Health and Medical Sciences, floor 7
Room: WS7058.01
Org Unit: Adelaide Medical School

Professor Sandra Hodge

Chronic Inflammatory Lung Disease Research Lab

Our Team

**Sandra HODGE, MSc, PhD, FThorSoc*: Brief Track Record***

Current research programs include:

Research funding acknowledgements

Appointments

Awards and Achievements

Education

Research Interests

Journals

Books

Book Chapters

Conference Papers

Conference Items

Grants & Funding

Current Funding: NHMRC

Current funding- non-NHMRC

Previous funding: NHMRC

Previous funding- non NHMRC

Current Higher Degree by Research Supervision (University of Adelaide)

Past Higher Degree by Research Supervision (University of Adelaide)

Other Supervision Activities

Board Memberships

Committee Memberships

Memberships

Consulting/Advisories

Offices Held

Connect With Me

External Profiles

Professor Sandra Hodge

Chronic Inflammatory Lung Disease Research Lab

Our Team

Sandra HODGE, MSc, PhD, FThorSoc: Brief Track Record

Current research programs include:

Research funding acknowledgements

Appointments

Awards and Achievements

Education

Research Interests

Journals

Books

Book Chapters

Conference Papers

Conference Items

Grants & Funding

Current Funding: NHMRC

Current funding- non-NHMRC

Previous funding: NHMRC

Previous funding- non NHMRC

Current Higher Degree by Research Supervision (University of Adelaide)

Past Higher Degree by Research Supervision (University of Adelaide)

Other Supervision Activities

Board Memberships

Committee Memberships

Memberships

Consulting/Advisories

Offices Held

Connect With Me

External Profiles

**Sandra HODGE, MSc, PhD, FThorSoc*: Brief Track Record***