Adelaide Medical School
Faculty of Health and Medical Sciences
Dr Samuel Costello - MBBS FRACP - TITLEHOLDER.
Gastroenterologist | Endoscopy and colonoscopy.
Dr Costello graduated from medical school at the University of Adelaide in 2004 and then completed basic physician training at the Royal Adelaide Hospital. Sam then completed Gastroenterology training at The Queen Elizabeth Hospital and Repatriation general hospital. He undertook a clinical fellowship in inflammatory bowel disease at St Mark’s hospital in London in 2016.
Sam is a staff specialist at The Queen Elizabeth Hospital and a consultant with the inflammatory bowel disease service. He established and continues to maintain the South Australian stool bank for the treatment of Clostridium difficile infection with faecal microbiota transplantation (FMT) and has advised other groups in Australia and internationally about developing similar services.
Sam is passionate about medical research. He is a PhD candidate at the University of Adelaide where the focus of his research has been FMT as a treatment for ulcerative colitis. He has published multiple papers in peer-reviewed international journals and has been an invited speaker at national and international conferences.
Sam enjoys teaching both medical students as well as doctors in training and is a clinical lecturer at the University of Adelaide.
Date Position Institution name 2015 Clnical Lecturer University of Adelaide 2013 Gastroenterologist The Queen Elizabeth Hospital
Date Institution name Country Title — University of Adelaide Australia MBBS
Date Title Institution Country — Gastroenterology Royal Australasian College of Physicians Australia
Year Citation 2019 Bryant, R., Schultz, C., Ooi, S., Goess, C., Costello, S., Vincent, A., . . . Andrews, J. (2019). Visceral Adipose Tissue Is Associated With Stricturing Crohn's Disease Behavior, Fecal Calprotectin, and Quality of Life. Inflammatory bowel diseases, 25(3), 592-600.
2019 Bryant, R., Schultz, C., Ooi, S., Goess, C., Costello, S., Vincent, A., . . . Andrews, J. (2019). Authors' reply: The Association Between Visceral Adipose Tissue and Stricturing Crohn's Disease Behavior, Fecal Calprotectin and Quality of Life. Inflammatory bowel diseases, 25(6), e62-e63.
2019 Costello, S., Hughes, P., Waters, O., Bryant, R., Vincent, A., Blatchford, P., . . . Andrews, J. (2019). Effect of fecal microbiota transplantation on 8-week remission in patients with ulcerative colitis: a randomized clinical trial. JAMA - Journal of the American Medical Association, 321(2), 156-164.
DOI Scopus8 WoS4 Europe PMC1
2019 Costello, S., & Bryant, R. (2019). Faecal microbiota transplantation in Australia: bogged down in regulatory uncertainty. Internal Medicine Journal, 49(2), 148-151.
2019 Papanicolas, L., Choo, J., Wang, Y., Leong, L., Costello, S., Gordon, D., . . . Rogers, G. (2019). Bacterial viability in faecal transplants: Which bacteria survive?. EBioMedicine, 41, 509-516.
2019 Wardill, H., Secombe, K., Bryant, R., Hazenberg, M., & Costello, S. (2019). Adjunctive fecal microbiota transplantation in supportive oncology: Emerging indications and considerations in immunocompromised patients. EBioMedicine.
2019 Selvanderan, S. P., Goldblatt, F., Nguyen, N., & Costello, S. P. (2019). Faecal microbiota transplantation for Clostridium difficile infection resulting in a decrease in psoriatic arthritis disease activity.. Clinical and experimental rheumatology, 37(3), 514-515. 2018 Bryant, R., Schultz, C., Ooi, S., Goess, C., Costello, S., Vincent, A., . . . Andrews, J. (2018). Obesity in inflammatory bowel disease: gains in adiposity despite high prevalence of Myopenia and Osteopenia. Nutrients, 10(9), 1192-1-1192-17.
DOI Scopus1 WoS1
2018 Bryant, R., Costello, S., Schoeman, S., Sathananthan, D., Knight, E., Lau, S. -Y., . . . Andrews, J. (2018). Limited uptake of ulcerative colitis 'treat to target' recommendations in real-world practice. Journal of gastroenterology and hepatology, 33(3), 599-607.
DOI Scopus5 WoS3 Europe PMC3
2017 Costello, S., Soo, W., Bryant, R., Jairath, V., Hart, A., & Andrews, J. (2017). Editorial: faecal microbiota transplantation for ulcerative colitis—not quite there yet? Authors’ reply. Alimentary Pharmacology and Therapeutics, 46(6), 631-632.
2017 Costello, S., Soo, W., Bryant, R., Jairath, V., Hart, A., & Andrews, J. (2017). Systematic review with meta-analysis: faecal microbiota transplantation for the induction of remission for active ulcerative colitis. Alimentary Pharmacology and Therapeutics, 46(3), 213-224.
DOI Scopus55 WoS50 Europe PMC31
2016 Costello, S., Tucker, E., La Brooy, J., Schoeman, M., & Andrews, J. (2016). Establishing a fecal microbiota transplant service for the treatment of Clostridium difficile infection. Clinical Infectious Diseases, 62(7), 908-914.
DOI Scopus32 WoS28 Europe PMC20
2016 Hughes, P., Costello, S., Bryant, R., & Andrews, J. (2016). Opioidergic effects on enteric and sensory nerves in the lower GI tract: basic mechanisms and clinical implications. American Journal of Physiology, 311(3), G501-G513.
DOI Scopus7 WoS5 Europe PMC3
2016 Andrews, J., Costello, S., Agarwal, A., Bampton, P., Beswick, L., Connor, S., . . . Walsh, A. (2016). Conflict of interest: Real and perceived - a more mature consideration is needed. Internal Medicine Journal, 46(3), 377-379.
2015 Costello, S., Chung, A., Andrews, J., & Fraser, R. (2015). Fecal microbiota transplant for Clostridium difficile colitis-induced toxic megacolon. American Journal of Gastroenterology, 110(5), 775-777.
DOI Scopus12 WoS12 Europe PMC6
2015 Costello, S., Ghaly, S., Beswick, L., Pudipeddi, A., Agarwal, A., Sechi, A., . . . Andrews, J. (2015). Compassionate access anti-tumour necrosis factor-α therapy for ulcerative colitis in Australia: the benefits to patients. Internal Medicine Journal, 45(6), 659-666.
DOI Scopus2 WoS2 Europe PMC2
2015 Costello, S., Conlon, M., Vuaran, M., Roberts-Thomson, I., & Andrews, J. (2015). Faecal microbiota transplant for recurrent Clostridium difficile infection using long-term frozen stool is effective: Clinical efficacy and bacterial viability data. Alimentary Pharmacology and Therapeutics, 42(8), 1011-1018.
DOI Scopus43 WoS39 Europe PMC29
2015 Ghaly, S., Costello, S., Beswick, L., Pudipeddi, A., Agarwal, A., Sechi, A., . . . Andrews, J. (2015). Dose tailoring of anti-tumour necrosis factor-alpha therapy delivers useful clinical efficacy in Crohn disease patients experiencing loss of response. Internal Medicine Journal, 45(2), 170-177.
2015 Bryant, R., Costello, S., & Andrews, J. (2015). Editorial: Untangling symptoms from mucosal healing in UC - A note of caution for patient-reported outcomes. Alimentary Pharmacology and Therapeutics, 42(11-12), 1327-1328.
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2004 Teague, B., Morrison, C., Court, F., Chin, V., Costello, S., Kirkwood, I., & Maddern, G. (2004). Role of FDG-PET in surgical management of patients with colorectal liver metastases. Australian and New Zealand Journal of Surgery, 74(8), 646-652.
DOI Scopus11 WoS8 Europe PMC6
Year Citation 2017 Noble, A., Durant, L., Hoyles, L., McCartney, A., Man, R., Costello, S., . . . Knight, S. (2017). Dysregulation of cellular vs humoral immunity to the intestinal microbiota in inflammatory bowel disease. In JOURNAL OF CROHNS & COLITIS Vol. 11 (pp. S123-S124). OXFORD UNIV PRESS. 2017 Costello, S., Van der Poorten, D., & Andrews, J. (2017). Fecal microbiota transplantation for recurrent Clostridium difficile infection: When regulatory affairs do not keep pace with evidence-based medicine. In JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Vol. 32 (pp. 156-157). WILEY. 2012 Agarwal, A., & Costello, S. P. (2012). Compassionate access (CA) use of anti-TNF therapy in inflammatory bowel disease (IBD) patients in Australia: an observational study. In JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Vol. 27 (pp. 96). WILEY-BLACKWELL. 2012 Costello, S. P., & Martin, J. (2012). Angioectasia in the Elderly is the Commonest Cause of Obscure Gastrointestinal Bleeding on Capsule Endoscopy. In GASTROINTESTINAL ENDOSCOPY Vol. 75 (pp. 260). San Diego, CA: MOSBY-ELSEVIER.
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