Saeed Nourmohammadi

Saeed Nourmohammadi

Higher Degree by Research Candidate

Adelaide Medical School

Faculty of Health and Medical Sciences


Aquaporins (AQPs) are members of the Major Intrinsic Protein (MIP) family of channels that facilitate fluid homeostasis across membranes of organisms in all kingdoms of life. The aquaporin family is divided into two groups; classical AQPs selectively carry water, while aquaglyceroporins behave as channels that are permeable to small-uncharged solutes. Recent discoveries in terms of the transport of a wider range of substrates have shed new light on AQP physiological roles. Their critical role in diverse physiological functions make AQP channels attractive targets for the discovery of pharmacological modulators. Certain types of cancers metastasize with aggressiveness that correlates with the level of AQPs expression. Yet, knowledge on the direct role of specific AQPs in animal
pathologies is still limited due to large number of different AQP isoforms and the lack of selective pharmacological modulators.

Our goals are to elucidate the signaling networks in AQP-related diseases, especially cancer metastasis in mammals, and discover novel AQP antagonist and agonist compounds as tools for clinical research. In future, cancer therapeutic interventions such as surgical, chemo and radiotherapy, might be found to benefit from adjunct treatment with AQP blockers for slowing cancer metastasis.

 

 

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  • Appointments

    Date Position Institution name
    2016 - 2017 Research assistant University of Adelaide, Adelaide
    2012 - 2013 Lab Manager Zar Macaron Company, Tehran, Iran
    2011 - 2012 Research assistant Shahid Beheshti University of Medical Sciences, Tehran
  • Awards and Achievements

    Date Type Title Institution Name Country Amount
    2018 Scholarship Adelaide Scholarships International (ASI) University of Adelaide Australia
    2018 Award Poster Prsentation The Australian Society for Medical Research (ASMR) Australia
    2013 Award ITQI award (International Taste and Quality Institute) Zarmacaron company Iran, Islamic Republic of
    2011 Achievement M.Sc First Class Grade Osmania University, Hyderabad India
  • Language Competencies

    Language Competency
    English Can read, write, speak, understand spoken and peer review
    Persian Can read, write, speak, understand spoken and peer review
  • Education

    Date Institution name Country Title
    Osmania University, Hyderabad India Master of Science
  • Research Interests

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  • Other Supervision Activities

    Date Role Research Topic Location Program Supervision Type Student Load Student Name
    2012 - 2012 Other The effect of injected allogeneic fibroblasts in patients suffering from Junctional epidermolysis bullosa Shahid Beheshti University of Medical Sciences Workshop Master Part Time Saeed Nourmohammadi
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  • Memberships

    Date Role Membership Country
    2019 - ongoing Member Australian Society for Biophysics (ASB) Australia
    2018 - ongoing Member Australian Society for Medical Research (ASMR) Australia

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