Saeed Nourmohammadi

Saeed Nourmohammadi

Higher Degree by Research Candidate

School of Biomedicine

Faculty of Health and Medical Sciences


Aquaporins (AQPs) are a subfamily of the Major Intrinsic Protein (MIP) that facilitate fluid homeostasis across membranes of organisms in all kingdoms of life. The aquaporin family is divided into two groups; classical AQPs selectively carry water, while aquaglyceroporins behave as channels that are permeable to small-uncharged solutes. Recent discoveries in terms of the transport of a wider range of substrates have shed new light on AQP physiological roles. Yet, knowledge on the direct role of specific AQPs in animal pathologies is still limited due to large number of different AQP isoforms and the lack of selective pharmacological modulators.

Using electrophysiology and molecular biology techniques in combination with computational modelling, my work primarily aims to discover new classes of AQPs that serve as dual water and ion channels and then provide better insights into the novel function of AQPs, their mechanism of gating and signaling networks in human-related diseases such as cancer and malaria. 

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Saeed has 5+ years of experience in plant and animal membrane protein channels research, and 10+ years of prior involvement in research and industry ranging from RA and TA to supervisor and senior executive roles in Iran, India and Australia.

He secured a role as an RA at Adelaide in 2017 before starting his PhD in 2018 in the School of Biomedicine, investigating the part that is challenging the decades-old paradigm that AQP channels carry only water and glycerol.

He has built comprehensive knowledge base using interdisciplinary combinations of methods, in both “wet” and “dry” labs, comprising Bioinformatics, Cell/Molecular Biology, Electrophysiology, Biochemistry, Molecular Docking to enable the understanding of AQPs as therapeutic targets in a diverse array of diseases. 

 

 

  • Appointments

    Date Position Institution name
    2022 - ongoing Tutor / Demonstrator (causal) University of Adelaide
    2016 - 2017 Research Assistant University of Adelaide
    2016 - 2016 Technical Assistant University of Adelaide
    2014 - 2015 Laboratory Manager Zar Macaron Company
    2012 - 2012 Teaching and Research Assistant (causal) Shahid Beheshti University of Medical Sciences
    2011 - 2013 R&D Zar Macaron Company
    2006 - 2008 Diagnostic Laboratory Technician Besat Hospital
  • Awards and Achievements

    Date Type Title Institution Name Country Amount
    2022 Award PhD Research Training Award (national award) Australian Physiological Society (AuPS) Australia
    2021 Award AMS/Biomedicine Publication Awards The University of Adelaide Australia
    2020 Award Free registration winner for Quality in Postgraduate Research Conference (QPR) The University of Adelaide Australia
    2019 Award School of Medicine Travel Award The University of Adelaide Australia
    2018 Research Award Best Poster Presentation Award Australian Society for Medical Research (ASMR) Australia
    2014 Recognition ITQI award (International Taste and Quality Institute) Zar Macaron company Iran, Islamic Republic of
    2009 Research Award Best Poster Presentation Award Osmania University India
  • Language Competencies

    Language Competency
    English Can read, write, speak, understand spoken and peer review
    Persian Can read, write, speak, understand spoken and peer review
  • Education

    Date Institution name Country Title
    2018 - 2022 University of Adelaide Australia Ph.D., Biomedicine
    2009 - 2011 Osmania University, Hyderabad India M.Sc., Biotechnology/Genetics
  • Research Interests

1- (National) AuPS Higher Degrees by Research Student Grant Scheme. (Best PhD project of the year 2022). Source: Australian Physiological Society (AuPs).

 

2-Associate investigator

Source: International corporation project of traditional Chinese medicine (GZYYGJ2017035) and the University of Adelaide Zhendong Australia China Centre for Molecular Chinese Medicine. Funding: (2018-2022).

Tutor/Demonstrator (2022)

  1. Foundations of Medicine course, Medical School, the University of Adelaide.
  2. Human Physiology A and B courses, Department of Physiology, the University of Adelaide.
  3. Honours Research Communication & Engagement course, Faculty of Health & Medical Sciences, the University of Adelaide.                              
  • Other Supervision Activities

    Date Role Research Topic Location Program Supervision Type Student Load Student Name
    2020 - ongoing Co-Supervisor Brain Cancer University of Adelaide The Bachelor of Health and Medical Sciences (BHMS) 3rd year Research Placement course-2020 Other Madison Boda, Annaliese Thompson, Timothy Kwok, Kenny Cao
    2020 - ongoing Co-Supervisor Brain Cancer University of Adelaide Honours Alanah Varricchio
    2012 - 2012 Other The effect of injected allogeneic fibroblasts in patients suffering from Junctional epidermolysis bullosa Shahid Beheshti University of Medical Sciences Workshop Master Part Time Pharmacology students
  • Mentoring

    Date Topic Location Name
    2019 - ongoing Endometrial Cancer, Insect pathology University of Adelaide Sidra Khan, Biko Muita
    2019 - 2020 Brain and Colorectal cancer University of Adelaide Zein Amro, Sher Lyn Yong
  • Community Engagement

    Date Title Engagement Type Institution Country
    2021 - ongoing National Relations Assistant and Conference Organizer Scientific Community Engagement The Australian Physiological Society
    2020 - ongoing Cultural ambassador Public Community Engagement The University of Adelaide
    2020 - ongoing Journal Reviewer Scientific Community Engagement Frontiers in Pharmacology journal
    2020 - ongoing Board member Scientific Community Engagement The University of Adelaide, Medical School, Helen Mayo Precinct
    2020 - ongoing Events Coordinator Head Scientific Community Engagement The University of Adelaide, Health Sciences Postgraduate Association (HeSPA)
  • Event Participation

    Date Event Name Event Type Institution Country
    2020 - ongoing Conference Assessor, 3rd Year Research Placement Students Conference The University of Adelaide
    2019 - ongoing Conference Assessor, Florey Undergraduate Research Conference Conference The University of Adelaide

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