Dr Ruby Dawson
ECR, Tumour Inflammation & Immunotherapy
SAIGENCI
College of Health
Eligible to supervise Masters and PhD (as Co-Supervisor) - email supervisor to discuss availability.
Dr Ruby Dawson is an early-career researcher (ECR) who has made significant contributions to cancer research and was recently recruited to the South Australian immunoGenomics Cancer Institute (SAiGENCI). Ruby’s work focuses on the roles of innate immune sensors in the development of gastric cancer and Helicobacter-induced gastric inflammation. Since completing her PhD at the University of Adelaide, Ruby has published two first-author papers in the prestigious Gut journal and Immunology and Cell Biology, which investigate the role of the innate immune DNA sensor, AIM2, in gastric inflammation and tumourigenesis. She is continuing this work with funding from a United States Department of Defense Cancer Research Program Idea Award received by Prof. Jenkins in 2022. She also has co-authorship on manuscripts in other reputable journals which investigate mechanisms of gastric cancer, a review on IL-6 family cytokines (Cytokine) and a book chapter based on the innate immune system in gastric cancer that is part of book series entitled “Research and Clinical Applications of Targeting Gastric Neoplasms” (Elsevier).Ruby is active in the wider scientific community as an elected junior council member of the International Cytokine and Interferon Society (ICIS) and an ECR representative on the Victorian Infection and Immunity Network (VIIN) Young Investigator Committee.
| Date | Position | Institution name |
|---|---|---|
| 2024 - ongoing | Postdoctoral Researcher | University of Adelaide |
| 2019 - 2023 | Postdoctoral Researcher | Hudson Institute of Medical Research |
| Year | Citation |
|---|---|
| 2024 | Dawson, R. E., & Jenkins, B. J. (2024). The Role of Inflammasome-Associated Innate Immune Receptors in Cancer. Immune network, 24(5), e38-1-e38-23. Scopus8 WoS8 Europe PMC8 |
| 2023 | Dawson, R. E., Deswaerte, V., West, A. C., Sun, E., Wray‐McCann, G., Livis, T., . . . Jenkins, B. J. (2023). The cytosolic DNA sensor AIM2 promotes Helicobacter‐induced gastric pathology via the inflammasome. Immunology and Cell Biology, 101(5), 444-457. Scopus9 WoS9 Europe PMC9 |
| 2022 | Tang, K., McLeod, L., Livis, T., West, A. C., Dawson, R., Yu, L., . . . Jenkins, B. J. (2022). Toll-like Receptor 9 Promotes Initiation of Gastric Tumorigenesis by Augmenting Inflammation and Cellular Proliferation. Cellular and Molecular Gastroenterology and Hepatology, 14(3), 567-586. Scopus15 WoS14 Europe PMC14 |
| 2022 | Dawson, R. E., Deswaerte, V., West, A. C., Tang, K., West, A. J., Balic, J. J., . . . Jenkins, B. J. (2022). STAT3-mediated upregulation of the AIM2 DNA sensor links innate immunity with cell migration to promote epithelial tumourigenesis. Gut, 71(8), 1515-1531. Scopus33 WoS32 Europe PMC29 |
| 2021 | Gurumurthy, C. B., O’Brien, A. R., Quadros, R. M., Adams, J., Alcaide, P., Ayabe, S., . . . Yoshiki, A. (2021). Response to correspondence on “Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation”. Genome Biology, 22(1), 99. Scopus2 WoS3 Europe PMC5 |
| 2021 | Thomson, E., Dawson, R., H'ng, C. H., Adikusuma, F., Piltz, S., & Thomas, P. Q. (2021). The Nestin neural enhancer is essential for normal levels of endogenous Nestin in neuroprogenitors but is not required for embryo development. PLoS One, 16(11), e0258538-1-e0258538-16. Scopus2 WoS4 Europe PMC2 |
| 2021 | Dawson, R. E., Jenkins, B. J., & Saad, M. I. (2021). IL-6 family cytokines in respiratory health and disease. Cytokine, 143, 1-10. Scopus38 WoS37 Europe PMC30 |
| 2020 | Dawson, R., Guil, A. N., Robertson, L., Piltz, S., Hughes, J., & Thomas, P. (2020). Functional screening of GATOR1 complex variants reveals a role for mTORC1 deregulation in FCD and focal epilepsy. Neurobiology of Disease, 134, 104640. Scopus39 WoS35 Europe PMC28 |
| 2020 | Balic, J. J., White, C. L., Dawson, R., Gough, D., McCormack, M. P., & Jenkins, B. J. (2020). STAT3-driven hematopoiesis and lymphopoiesis abnormalities are dependent on serine phosphorylation. Cytokine, 130, 155059. Scopus5 WoS4 Europe PMC3 |
| 2020 | Balic, J. J., Saad, M. I., Dawson, R., West, A. J., McLeod, L., West, A. C., . . . Jenkins, B. J. (2020). Constitutive STAT3 Serine Phosphorylation Promotes Helicobacter-Mediated Gastric Disease. The American Journal of Pathology, 190(6), 1256-1270. Scopus24 WoS19 Europe PMC20 |
| 2019 | Gurumurthy, C. B., O'Brien, A. R., Quadros, R. M., Adams, J., Alcaide, P., Ayabe, S., . . . Yoshiki, A. (2019). Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: A multi-center evaluation. Genome Biology, 20(1), 14 pages. Scopus64 WoS54 Europe PMC63 |
| 2017 | Hughes, J., Dawson, R., Tea, M., McAninch, D., Piltz, S., Jackson, D., . . . Thomas, P. (2017). Knockout of the epilepsy gene Depdc5 in mice causes severe embryonic dysmorphology with hyperactivity of mTORC1 signalling. Scientific Reports, 7(1), 12618-1-12618-15. Scopus51 WoS47 Europe PMC45 |
| Year | Citation |
|---|---|
| 2021 | Dawson, R., & Jenkins, B. J. (2021). Unravelling the pro-tumorigenic role of innate immune pattern recognition receptors in the gastric compartment. In Research and Clinical Applications of Targeting Gastric Neoplasms (pp. 43-90). Elsevier. DOI |
| 2018 | Thomson, E. P., Dawson, R. E., Hughes, J. N., & Thomas, P. Q. (2018). CRISPR Genome Editing in Mice. In Genome Editing and Engineering: From TALENs, ZFNs and CRISPRs to Molecular Surgery (pp. 165-180). Cambridge University Press. DOI |
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