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Professor Robert McLaughlin

Robert McLaughlin
Chair of Biophotonics
Adelaide Medical School
Faculty of Health and Medical Sciences

I am head of the Bioengineering Imaging Group at The University Adelaide, and am also Managing Director of the medical device start-up company, Miniprobes. I currently lead a research team developing highly miniaturised imaging probes, small enough to be encased within hypodermic needles. My team of engineers, physicists and computer scientists is based in the Centre for Nanoscale Biophotonics and is part of the Institute for Photonics and Advanced Sensing.

After three years as a researcher at the University of Oxford, I spent five years in the medical imaging industry, including as a Product Manager with Siemens Medical Solutions. I was responsible for the development of three medical devices, two with FDA regulatory approval.

Returning to academia in 2007, I have focused on the development of optical imaging technologies, particularly optical coherence tomography and fluorescence. I have been awarded over $5M in research grants. With 12 years of research experience, I have a Google Scholar h-index of 27. I have co-authored 2 book chapters, 7 patents and 66 journal papers. I received the 2014 WA Innovator of the Year Award, and the 2015 Australian Innovation Challenge. In 2016, I was awarded the prestigious South Australian Premier’s Research and Industry Fund Research Fellowship.

In 2014, I was appointed as a Councilor of the Australian Optical Society. In 2016, I was appointed Chair of Biophotonics at the University of Adelaide.

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External Profiles

Professor Robert McLaughlin

I am head of the Bioengineering Imaging Group at The University Adelaide, and am also Managing Director of the medical device start-up company, Miniprobes. I currently lead a research team developing highly miniaturised imaging probes, small enough to be encased within hypodermic needles. My team of engineers, physicists and computer scientists is based in the Centre for Nanoscale Biophotonics and is part of the Institute for Photonics and Advanced Sensing.

After three years as a researcher at the University of Oxford, I spent five years in the medical imaging industry, including as a Product Manager with Siemens Medical Solutions. I was responsible for the development of three medical devices, two with FDA regulatory approval.

Returning to academia in 2007, I have focused on the development of optical imaging technologies, particularly optical coherence tomography and fluorescence. I have been awarded over $5M in research grants. With 12 years of research experience, I have a Google Scholar h-index of 27. I have co-authored 2 book chapters, 7 patents and 66 journal papers. I received the 2014 WA Innovator of the Year Award, and the 2015 Australian Innovation Challenge. In 2016, I was awarded the prestigious South Australian Premier’s Research and Industry Fund Research Fellowship.

In 2014, I was appointed as a Councilor of the Australian Optical Society. In 2016, I was appointed Chair of Biophotonics at the University of Adelaide.

Awards and Achievements

Date Type Title Institution Name Country Amount
2015 Award The Australian Innovation Challenge
2014 Award Western Australian Innovator of the Year, WA Department of Commerce
2014 Award UWA Vice-Chancellor’s Mid-career Research Award
2014 Award UWA Vice-Chancellor’s Award for Impact and Innovation
2014 Award 1st prize, SPIE Start-up Challenge, San Francisco United States
2013 Award Finalist, Australian Museum Eureka Prizes: “Innovative Use of Technology”
2012 Award Finalist, Australian Museum Eureka Prizes: “Innovative Use of Technology”
2012 Award Finalist, Centenary Institute Lawrence Creative Prize
2011 Award National Breast Cancer Foundation Patron’s Award: “Innovation and Vision in Research”

Education

Date Institution name Country Title
2000 University of Western Australia Australia PhD (Electronic Engineering)
1993 University of Western Australia Australia Bachelor of Engineering (Honours)

Research Interests

Journals

Year Citation
2018 Tan, L. K., McLaughlin, R. A., Lim, E., Abdul Aziz, Y. F., & Liew, Y. M. (2018). Fully automated segmentation of the left ventricle in cine cardiac MRI using neural network regression.. Journal of magnetic resonance imaging : JMRI.
DOI
2018 Li, J., & E. Schartner, S. Musolino, B. Quirk, R. Kirk, H. Ebendorff-Heidepriem, R. McLaughlin. (2018). Miniaturized single-fiber-based needle probe for combined imaging and sensing in deep tissue. Optics Letters, 43(8), 1682-1685.
DOI
2017 Li, J., Quirk, B., Noble, P., Kirk, R., Sampson, D., & McLaughlin, R. (2017). Flexible needle with integrated optical coherence tomography probe for imaging during transbronchial tissue aspiration. Journal of Biomedical Optics, 22(10), 106002-1-106002-5.
DOI
2017 Tan, L., Liew, Y., Lim, E., Abdul Aziz, Y., Chee, K., & McLaughlin, R. (2017). Automatic localization of the left ventricular blood pool centroid in short axis cardiac cine MR images. Medical and Biological Engineering and Computing, OnlinePubl, 1-10.
DOI
2017 Yong, Y., Tan, L., McLaughlin, R., Chee, K., & Liew, Y. (2017). Linear-regression convolutional neural network for fully automated coronary lumen segmentation in intravascular optical coherence tomography. Journal of Biomedical Optics, 22(12), 126005-1-126005-9.
DOI
2017 Tan, L., Liew, Y., Lim, E., & McLaughlin, R. (2017). Convolutional neural network regression for short-axis left ventricle segmentation in cardiac cine MR sequences. Medical Image Analysis, 39, 78-86.
DOI Scopus6 WoS6 Europe PMC4
2017 Es Haghian, S., Kennedy, K., Gong, P., Li, Q., Chin, L., Wijesinghe, P., . . . Kennedy, B. (2017). In vivo volumetric quantitative micro-elastography of human skin. Biomedical Optics Express, 8(5), 2458-2471.
DOI Scopus2 WoS3 Europe PMC1
2017 Es'haghian, S., Gong, P., Chin, L., Harms, K., Murray, A., Rea, S., . . . Mclaughlin, R. (2017). Investigation of optical attenuation imaging using optical coherence tomography for monitoring of scars undergoing fractional laser treatment. Journal of Biophotonics, 10(4), 511-522.
DOI Scopus1 WoS1 Europe PMC1
2016 Villiger, M., Lorenser, D., McLaughlin, R., Quirk, B., Kirk, R., Bouma, B., & Sampson, D. (2016). Deep tissue volume imaging of birefringence through fibre-optic needle probes for the delineation of breast tumour. Scientific Reports, 6(1), 28771-1-28771-11.
DOI Scopus26 WoS20 Europe PMC10
2016 Gong, P., Es'haghian, S., Wood, F., Sampson, D., & McLaughlin, R. (2016). Optical coherence tomography angiography for longitudinal monitoring of vascular changes in human cutaneous burns. Experimental Dermatology, 25(9), 722-724.
DOI Scopus3 WoS2 Europe PMC2
2016 Gong, P., Es'haghian, S., Harms, K., Murray, A., Rea, S., Kennedy, B., . . . McLaughlin, R. (2016). Optical coherence tomography for longitudinal monitoring of vasculature in scars treated with laser fractionation. Journal of Biophotonics, 9(6), 626-636.
DOI Scopus11 WoS10 Europe PMC9
2016 Carter, H., Gong, P., Kirk, R., Eshaghian, S., Atkinson, C., Sampson, D., . . . Mclaughlin, R. (2016). Optical coherence tomography in the assessment of acute changes in cutaneous vascular diameter induced by heat stress. Journal of Applied Physiology, 121(4), 965-972.
DOI Scopus5 WoS4 Europe PMC5
2016 Ho, L., Thomas, E., McLaughlin, R., Flematti, G., & Fuller, R. (2016). A new selective fluorescent probe based on tamoxifen. Bioorganic and Medicinal Chemistry Letters, 26(20), 4879-4883.
DOI Scopus3 WoS3 Europe PMC1
2016 Kennedy, K., Chin, L., Wijesinghe, P., McLaughlin, R., Latham, B., Sampson, D., . . . Kennedy, B. (2016). Investigation of optical coherence micro-elastography as a method to visualize micro-architecture in human axillary lymph nodes. BMC Cancer, 16(1), 874-1-874-9.
DOI Scopus2 WoS2 Europe PMC1
2016 Gong, P., Es haghian, S., Harms, K., Murray, A., Rea, S., Wood, F., . . . McLaughlin, R. (2016). In vivo label-free lymphangiography of cutaneous lymphatic vessels in human burn scars using optical coherence tomography. Biomedical Optics Express, 7(12), 4886-4898.
DOI Scopus5 WoS3 Europe PMC2
2015 Scolaro, L., Lorenser, D., Madore, W., Kirk, R., Kramer, A., Yeoh, G., . . . McLaughlin, R. (2015). Molecular imaging needles: dual-modality optical coherence tomography and fluorescence imaging of labeled antibodies deep in tissue. Biomedical Optics Express, 6(5), 1767-1781.
DOI Scopus20 WoS15 Europe PMC5
2015 Kennedy, B., McLaughlin, R., Kennedy, K., Chin, L., Wijesinghe, P., Curatolo, A., . . . Sampson, D. (2015). Investigation of optical coherence microelastography as a method to visualize cancers in human breast tissue. Cancer Research, 75(16), 3236-3245.
DOI Scopus31 WoS25 Europe PMC11
2015 Ansell, T., McFawn, P., McLaughlin, R., Sampson, D., Eastwood, P., Hillman, D., . . . Noble, P. (2015). Does smooth muscle in an intact airway undergo length adaptation during a sustained change in transmural pressure?. Journal of Applied Physiology, 118(5), 533-543.
DOI Scopus8 WoS7 Europe PMC6
2015 Wijesinghe, P., McLaughlin, R., Sampson, D., & Kennedy, B. (2015). Parametric imaging of viscoelasticity using optical coherence elastography. Physics in Medicine and Biology, 60(6), 2293-2307.
DOI Scopus13 WoS11 Europe PMC2
2015 Es'Haghian, S., Kennedy, K., Gong, P., Sampson, D., McLaughlin, R., & Kennedy, B. (2015). Optical palpation in vivo: Imaging human skin lesions using mechanical contrast. Journal of Biomedical Optics, 20(1), 16013.
DOI Scopus13 Europe PMC4
2015 Kennedy, K., Chin, L., McLaughlin, R., Latham, B., Saunders, C., Sampson, D., & Kennedy, B. (2015). Quantitative micro-elastography: imaging of tissue elasticity using compression optical coherence elastography. Scientific Reports, 5(1), 15538.
DOI Scopus58 WoS53 Europe PMC22
2015 Kirk, R. W., Kennedy, B. F., Sampson, D. D., & McLaughlin, R. A. (2015). Near video-rate Optical coherence elastography by acceleration with a graphics processing unit. Journal of Lightwave Technology, 33(16), 3481-3485.
DOI Scopus15 WoS11
2015 Jahanzad, Z., Liew, Y., Bilgen, M., McLaughlin, R., Leong, C., Chee, K., . . . Lim, E. (2015). Regional assessment of LV wall in infarcted heart using tagged MRI and cardiac modelling. Physics in Medicine and Biology, 60(10), 4015-4031.
DOI Scopus3 WoS3 Europe PMC2
2015 Liew, Y., McLaughlin, R., Chan, B., Aziz, Y., Chee, K., Ung, N., . . . Lim, E. (2015). Motion corrected LV quantification based on 3D modelling for improved functional assessment in cardiac MRI. Physics in Medicine and Biology, 60(7), 2715-2733.
DOI Scopus6 WoS7 Europe PMC5
2014 Scolaro, L., McLaughlin, R., Kennedy, B., Saunders, C., & Sampson, D. (2014). A review of optical coherence tomography in breast cancer. Photonics and Lasers in Medicine, 3(3), 225-240.
DOI Scopus13
2014 Kennedy, B., Chin, L., Kennedy, K., Wijesinghe, P., Curatolo, A., Es'haghian, S., . . . Sampson, D. (2014). A new window into disease. Optics and Photonics News, 25(12), 55.
2014 Kennedy, K., Es'haghian, S., Chin, L., McLaughlin, R., Sampson, D., & Kennedy, B. (2014). Optical palpation: optical coherence tomography-based tactile imaging using a compliant sensor. Optics Letters, 39(10), 3014-3017.
DOI Scopus40 WoS32 Europe PMC15
2014 Quirk, B., McLaughlin, R., Pagnozzi, A., Kennedy, B., Noble, P., & Sampson, D. (2014). Optofluidic needle probe integrating targeted delivery of fluid with optical coherence tomography imaging. Optics Letters, 39(10), 2888-2891.
DOI Scopus10 WoS7 Europe PMC5
2014 Gong, P., McLaughlin, R., Liew, Y., Munro, P., Wood, F., & Sampson, D. (2014). Assessment of human burn scars with optical coherence tomography by imaging the attenuation coefficient of tissue after vascular masking. Journal of Biomedical Optics, 19(2), 21111.
DOI Scopus30 WoS19 Europe PMC12
2014 Gong, P., Chin, L., Es'Haghian, S., Liew, Y., Wood, F., Sampson, D., & McLaughlin, R. (2014). Imaging of skin birefringence for human scar assessment using polarization-sensitive optical coherence tomography aided by vascular masking. Journal of Biomedical Optics, 19(12), 126014.
DOI Scopus13 WoS14 Europe PMC6
2014 Chin, L., Kennedy, B., Kennedy, K., Wijesinghe, P., Pinniger, G., Terrill, J., . . . Sampson, D. (2014). Three-dimensional optical coherence microelastography of skeletal muscle tissue. Biomedical Optics Express, 5(9), 3090-3102.
DOI Scopus15 WoS14 Europe PMC6
2014 Chin, L., Curatolo, A., Kennedy, B., Doyle, B., Munro, P., McLaughlin, R., & Sampson, D. (2014). Analysis of image formation in optical coherence elastography using a multiphysics approach. Biomedical Optics Express, 5(9), 2913-2930.
DOI Scopus28 WoS28 Europe PMC13
2014 McLaughlin, R., Noble, P., & Sampson, D. (2014). Optical coherence tomography in respiratory science and medicine: from airways to alveoli. Physiology, 29(5), 369-380.
DOI Scopus14 WoS13 Europe PMC10
2014 Kennedy, B., Mclaughlin, R., Kennedy, K., Chin, L., Curatolo, A., Tien, A., . . . Sampson, D. (2014). Optical coherence micro-elastography: mechanical-contrast imaging of tissue microstructure. Biomedical Optics Express, 5(7), 2113-2124.
DOI Scopus65 WoS54 Europe PMC34
2013 Yang, X., Lorenser, D., McLaughlin, R., Kirk, R., Edmond, M., Cather Simpson, M., . . . Sampson, D. (2013). Imaging deep skeletal muscle structure using a high-sensitivity ultrathin side-viewing optical coherence tomography needle probe. Biomedical Optics Express, 5(1), 136-148.
DOI Scopus27 WoS20 Europe PMC7
2013 Kennedy, K., McLaughlin, R., Kennedy, B., Tien, A., Latham, B., Saunders, C., & Sampson, D. (2013). Needle optical coherence elastography for the measurement of microscale mechanical contrast deep within human breast tissues. Journal of Biomedical Optics, 18(12), 121510-1-121510-8.
DOI Scopus37 WoS27 Europe PMC19
2013 Pagnozzi, A., Kirk, R., Kennedy, B., Sampson, D., & McLaughlin, R. (2013). Automated quantification of lung structures from optical coherence tomography images. Biomedical Optics Express, 4(11), 2383-2395.
DOI Scopus5 WoS5 Europe PMC5
2013 Yang, X., Chin, L., Klyen, B., Shavlakadze, T., McLaughlin, R., Grounds, M., & Sampson, D. (2013). Quantitative assessment of muscle damage in the mdx mouse model of Duchenne muscular dystrophy using polarization-sensitive optical coherence tomography. Journal of Applied Physiology, 115(9), 1393-1401.
DOI Scopus10 WoS10 Europe PMC8
2013 Chin, L., Yang, X., McLaughlin, R., Noble, P., & Sampson, D. (2013). En face parametric imaging of tissue birefringence using polarization-sensitive optical coherence tomography. Journal of Biomedical Optics, 18(6), 066005-1-066005-5.
DOI Scopus15 WoS12 Europe PMC8
2013 Lorenser, D., Quirk, B., Auger, M., Madore, W., Kirk, R., Godbout, N., . . . McLaughlin, R. (2013). Dual-modality needle probe for combined fluorescence imaging and three-dimensional optical coherence tomography. Optics Letters, 38(3), 266-268.
DOI Scopus37 WoS32 Europe PMC17
2013 Liew, Y., McLaughlin, R., Gong, P., Wood, F., & Sampson, D. (2013). In vivo assessment of human burn scars through automated quantification of vascularity using optical coherence tomography. Journal of Biomedical Optics, 18(6), 061213.
DOI Scopus43 WoS37 Europe PMC19
2013 Liew, Y., McLaughlin, R., Gong, P., Wood, F., & Sampson, D. (2013). Erratum: In vivo assessment of human burn scars through automated quantification of vascularity using optical coherence tomography (Journal of Biomedical Optics (2013) 18 (061213)). Journal of Biomedical Optics, 18(6), 1 page.
DOI
2012 McLaughlin, R., Quirk, B., Curatolo, A., Kirk, R., Scolaro, L., Lorenser, D., . . . Sampson, D. (2012). Imaging of breast cancer with optical coherence tomography needle probes: Feasibility and initial results. IEEE Journal on Selected Topics in Quantum Electronics, 18(3), 1184-1191.
DOI Scopus64 WoS49
2012 Liew, Y., McLaughlin, R., Wood, F., & Sampson, D. (2012). Motion correction of in vivo three-dimensional optical coherence tomography of human skin using a fiducial marker. Biomedical Optics Express, 3(8), 1774-1786.
DOI Scopus19 WoS18 Europe PMC10
2012 Kennedy, B., Koh, S., McLaughlin, R., Kennedy, K., Munro, P., & Sampson, D. (2012). Strain estimation in phase-sensitive optical coherence elastography. Biomedical Optics Express, 3(8), 1865-1879.
DOI Scopus65 WoS61 Europe PMC28
2012 Yeo, B., McLaughlin, R., Kirk, R., & Sampson, D. (2012). Enabling freehand lateral scanning of optical coherence tomography needle probes with a magnetic tracking system. Biomedical Optics Express, 3(7), 1565-1578.
DOI Scopus14 WoS10 Europe PMC6
2012 Scolaro, L., McLaughlin, R., Klyen, B., Wood, B., Robbins, P., Saunders, C., . . . Sampson, D. (2012). Parametric imaging of the local attenuation coefficient in human axillary lymph nodes assessed using optical coherence tomography. Biomedical Optics Express, 3(2), 366-379.
DOI Scopus35 WoS29 Europe PMC21
2012 Curatolo, A., McLaughlin, R., Quirk, B., Kirk, R., Bourke, A., Wood, B., . . . Sampson, D. (2012). Ultrasound-guided optical coherence tomography needle probe for the assessment of breast cancer tumor margins. American Journal of Roentgenology, 199(4), W520-W522.
DOI Scopus22 WoS18 Europe PMC9
2012 McLaughlin, R., Yang, X., Quirk, B., Lorenser, D., Kirk, R., Noble, P., & Sampson, D. (2012). Static and dynamic imaging of alveoli using optical coherence tomography needle probes. Journal of Applied Physiology, 113(6), 967-974.
DOI Scopus33 WoS29 Europe PMC17
2012 Kennedy, K., Kennedy, B., McLaughlin, R., & Sampson, D. (2012). Needle optical coherence elastography for tissue boundary detection. Optics Letters, 37(12), 2310-2312.
DOI Scopus44 WoS41 Europe PMC23
2012 Scolaro, L., Lorenser, D., McLaughlin, R., Quirk, B., Kirk, R., & Sampson, D. (2012). High-sensitivity anastigmatic imaging needle for optical coherence tomography. Optics Letters, 37(24), 5247-5249.
DOI Scopus23 WoS14 Europe PMC8
2011 Liew, Y., McLaughlin, R., Wood, F., & Sampson, D. (2011). Reduction of image artifacts in three-dimensional optical coherence tomography of skin in vivo. Journal of Biomedical Optics, 16(11), 116018.
DOI Scopus19 WoS18 Europe PMC12
2011 Lorenser, D., Yang, X., Kirk, R., Quirk, B., McLaughlin, R., & Sampson, D. (2011). Ultrathin side-viewing needle probe for optical coherence tomography. Optics Letters, 36(19), 3894-3896.
DOI Scopus92 WoS80 Europe PMC42
2011 Quirk, B., McLaughlin, R., Curatolo, A., Kirk, R., Noble, P., & Sampson, D. (2011). In situ imaging of lung alveoli with an optical coherence tomography needle probe. Journal of Biomedical Optics, 16(3), 036009-1-036009-4.
DOI Scopus57 WoS45 Europe PMC26
2011 Williamson, J., McLaughlin, R., Noffsinger, W., James, A., Baker, V., Curatolo, A., . . . Eastwood, P. (2011). Elastic properties of the central airways in obstructive lung diseases measured using anatomical optical coherence tomography. American Journal of Respiratory and Critical Care Medicine, 183(5), 612-619.
DOI Scopus55 WoS47 Europe PMC39
2010 Noble, P., West, A., McLaughlin, R., Armstrong, J., Becker, S., McFawn, P., . . . Mitchell, H. (2010). Airway narrowing assessed by anatomical optical coherence tomography in vitro: Dynamic airway wall morphology and function. Journal of Applied Physiology, 108(2), 401-411.
DOI Scopus27 WoS26 Europe PMC18
2010 Kennedy, B., Loitsch, S., McLaughlin, R., Scolaro, L., Rigby, P., & Sampsona, D. (2010). Fibrin phantom for use in optical coherence tomography. Journal of Biomedical Optics, 15(3), 3 pages.
DOI Scopus30 WoS21 Europe PMC11
2010 Williamson, J., Armstrong, J., McLaughlin, R., Noble, P., West, A., Becker, S., . . . Eastwood, P. (2010). Measuring airway dimensions during bronchoscopy using anatomical optical coherence tomography. European Respiratory Journal, 35(1), 34-41.
DOI Scopus48 WoS41 Europe PMC28
2010 Noble, P., McLaughlin, R., West, A., Becker, S., Armstrong, J., McFawn, P., . . . Mitchell, H. (2010). Distribution of airway narrowing responses across generations and at branching points, assessed in vitro by anatomical optical coherence tomography. Respiratory Research, 11(1), 12 pages.
DOI Scopus12 WoS9 Europe PMC7
2010 McLaughlin, R., & Sampson, D. (2010). Clinical applications of fiber-optic probes in optical coherence tomography. Optical Fiber Technology, 16(6), 467-475.
DOI Scopus17 WoS14
2010 Lau, B., McLaughlin, R., Curatolo, A., Kirk, R., Gerstmann, D., & Sampson, D. (2010). Imaging true 3D endoscopic anatomy by incorporating magnetic tracking with optical coherence tomography: Proof-of-principle for airways. Optics Express, 18(26), 27173-27180.
DOI Scopus23 WoS18 Europe PMC13
2010 Williamson, J., McLaughlin, R., Phillips, M., Curatolo, A., Armstrong, J., Maddison, K., . . . Eastwood, P. (2010). Feasibility of applying real-time optical imaging during bronchoscopic interventions for central airway obstruction. Journal of Bronchology and Interventional Pulmonology, 17(4), 307-316.
DOI Scopus7 Europe PMC3
2010 McLaughlin, R., Scolaro, L., Robbins, P., Saunders, C., Jacques, S., & Sampson, D. (2010). Parametric imaging of cancer with optical coherence tomography. Journal of Biomedical Optics, 15(4), 4 pages.
DOI Scopus47 WoS33 Europe PMC17
2010 McLaughlin, R. A., Scolaro, L., Robbins, P., Hamza, S., Saunders, C., & Sampson, D. D. (2010). Imaging of Human Lymph Nodes Using Optical Coherence Tomography: Potential for Staging Cancer. CANCER RESEARCH, 70(7), 2579-2584.
DOI WoS50 Europe PMC33
2009 Kennedy, B., Hillman, T., McLaughlin, R., Quirk, B., & Sampson, D. (2009). In vivo dynamic optical coherence elastography using a ring actuator. Optics Express, 17(24), 21762-21772.
DOI Scopus86 WoS85 Europe PMC51
2009 Mclaughlin, R., Armstrong, J., Becker, S., Walsh, J., Jain, A., Hillman, D., . . . Sampson, D. (2009). Respiratory gating of Anatomical optical coherence tomography images of the human airway. Optics Express, 17(8), 6568-6577.
DOI Scopus20 WoS17 Europe PMC14
2009 Williamson, J., McLaughlin, R., Phillips, M., Armstrong, J., Becker, S., Walsh, J., . . . Eastwood, P. (2009). Using optical coherence tomography to improve diagnostic and therapeutic bronchoscopy. Chest, 136(1), 272-276.
DOI Scopus40 WoS31 Europe PMC24
2009 McLaughlin, R., Scolaro, L., Robbins, P., Saunders, C., Jacques, S., & Sampson, D. (2009). Mapping tissue optical attenuation to identify cancer using optical coherence tomography.. Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention, 12(Pt 2), 657-664.
Scopus12 Europe PMC8
2008 McLaughlin, R., Williamson, J., Phillips, M., Armstrong, J., Becker, S., Hillman, D., . . . Sampson, D. (2008). Applying anatomical optical coherence tomography to quantitative 3D imaging of the lower airway. Optics Express, 16(22), 17521-17529.
DOI Scopus33 WoS31 Europe PMC19
2006 Mclaughlin, R. A. (2006). Extracting Transmission Lines From Airborne LIDAR Data. IEEE Geoscience and Remote Sensing Letters, 3(2), 222-226.
DOI
2005 McLaughlin, R. A., Hipwell, J., Hawkes, D. J., Noble, J. A., Byrne, J. V., & Cox, T. C. (2005). A comparison of a similarity-based and a feature-based 2-D-3-D registration method for neurointerventional use. IEEE Transactions on Medical Imaging, 24(8), 1058-1066.
DOI
2003 Hipwell, J. H., Penney, G. P., McLaughlin, R. A., Rhode, K., Summers, P., Cox, T. C., . . . Hawkes, D. J. (2003). Intensity-based 2-D-3-D registration of cerebral angiograms. IEEE Transactions on Medical Imaging, 22(11), 1417-1426.
DOI
1998 McLaughlin, R. A., & Alder, M. D. (1998). The Hough transform versus the UpWrite. IEEE Transactions on Pattern Analysis and Machine Intelligence, 20(4), 396-400.
DOI
1998 McLaughlin, R. A. (1998). Randomized Hough Transform: Improved ellipse detection with comparison. Pattern Recognition Letters, 19(3-4), 299-305.
DOI
1994 McLaughlin, R. A., Alder, M. D., & deSilva, C. J. (1994). Inference of structure: hands. Pattern Recognition Letters, 15(10), 957-962.
DOI

Book Chapters

Year Citation
2015 Lorenser, D., McLaughlin, R. A., & Sampson, D. D. (2015). Optical coherence tomography in a needle format. In W. Drexler, & J. G. Fujimoto (Eds.), Optical Coherence Tomography Technology and Applications (2nd ed., pp. 2413-2472). Springer.
2013 McLaughlin, R., Lorenser, D., & Sampson, D. (2013). Needle probes in optical coherence tomography. In Handbook of Coherent-Domain Optical Methods: Biomedical Diagnostics, Environmental Monitoring, and Materials Science:: Second Edition (Vol. 2-2, pp. 1065-1102).
DOI Scopus9

Conference Papers

Year Citation
2017 Gong, P., Es'Haghian, S., Harms, K., Murray, A., Rea, S., Wood, F., . . . McLaughlin, R. (2017). Extracting something from nothing: In vivo imaging of human cutaneous lymphatic vessels using optical coherence tomography. In Proceedings of the 29th IEEE Photonics Conference (IPC 2016) (pp. 138-139). Piscataway, NJ: IEEE.
DOI
2017 Tan, L., Liew, Y., Lim, E., & McLaughlin, R. (2017). Cardiac left ventricle segmentation using convolutional neural network regression. In Proceedings of the IEEE EMBS Conference on Biomedical Engineering and Sciences (IECBES 2016) (pp. 490-493). Kuala Lumpur, MALAYSIA: IEEE.
DOI Scopus2
2016 Villiger, M., Lorenser, D., McLaughlin, R. A., Quirk, B. C., Kirk, R. W., Bouma, B. E., & Sampson, D. D. (2016). Needle-based polarization-sensitive OCT of breast tumor. In J. Izatt, J. Fujimoto, & V. Tuchin (Eds.), OPTICAL COHERENCE TOMOGRAPHY AND COHERENCE DOMAIN OPTICAL METHODS IN BIOMEDICINE XX Vol. 9697 (pp. 1 page). San Francisco, CA: SPIE-INT SOC OPTICAL ENGINEERING.
DOI
2016 Sampson, D. D., Chin, L., Gong, P., Wijesinghe, P., Es'haghian, S., Allen, W. M., . . . McLaughlin, R. A. (2016). Parametric approaches to micro-scale characterization of tissue volumes in vivo and ex vivo: Imaging microvasculature, attenuation, birefringence, and stiffness (Conference Presentation). In R. Alfano, & S. Demos (Eds.), OPTICAL BIOPSY XIV: TOWARD REAL-TIME SPECTROSCOPIC IMAGING AND DIAGNOSIS Vol. 9703 (pp. 1 page). San Francisco, CA: SPIE-INT SOC OPTICAL ENGINEERING.
DOI
2015 Villiger, M., Lorenser, D., Quirk, B., Kirk, R., Lippok, N., Bouma, B., . . . Sampson, D. (2015). Polarization sensitive OCT with needle probes. In 2015 IEEE Photonics Conference, IPC 2015 (pp. 12-13). Reston, VA: IEEE.
DOI
2015 Chin, L., Curatolo, A., Wijesinghe, P., Kennedy, K., McLaughlin, R., Kennedy, B., & Sampson, D. (2015). Sensitivity and resolution in optical coherence micro-elastography. In 2015 IEEE Photonics Conference, IPC 2015 (pp. 1-2). Reston, VA: IEEE.
DOI
2015 Es'haghian, S., Gong, P., Kennedy, K., Wijesinghe, P., Sampson, D., McLaughlin, R., & Kennedy, B. (2015). In vivo optical elastography: Stress and strain imaging of human skin lesions. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE Vol. 9327 (pp. 1-8). San Francisco: SPIE-INT SOC OPTICAL ENGINEERING.
DOI Scopus1
2013 McLaughlin, R., Lorenser, D., & Sampson, D. (2013). Fiber-optic needle probes: Applications in deep tissue Imaging. In Asia Communications and Photonics Conference, ACP.
2013 Kennedy, K., Kennedy, B., McLaughlin, R., Ford, C., Bush, M., & Sampson, D. (2013). Measuring elastic contrast in tissue using OCT needle probes. In J. Fujimoto, J. Izatt, & V. Tuchin (Eds.), Progress in Biomedical Optics and Imaging - Proceedings of SPIE Vol. 8571 (pp. 7 pages). San Francisco, CA: SPIE-INT SOC OPTICAL ENGINEERING.
DOI Scopus1 WoS1
2013 Chin, L., Yang, X., McLaughlin, R., Noble, P., & Sampson, D. (2013). Birefringence imaging for optical sensing of tissue damage. In M. Palaniswami, C. Leckie, S. Kanhere, & J. Gubbi (Eds.), Proceedings of the 2013 IEEE 8th International Conference on Intelligent Sensors, Sensor Networks and Information Processing: Sensing the Future, ISSNIP 2013 Vol. 1 (pp. 45-48). Melbourne, AUSTRALIA: IEEE.
DOI
2012 Kennedy, B., Kennedy, K., Ford, C., McLaughlin, R., Bush, M., & Sampson, D. (2012). Optical coherence elastography: Strain imaging in tissue using optical coherence tomography. In Y. Liao, W. Jin, D. Sampson, R. Yamauchi, Y. Chung, K. Nakamura, & Y. Rao (Eds.), Proceedings of SPIE - The International Society for Optical Engineering Vol. 8421 (pp. 4 pages). Beijing, PEOPLES R CHINA: SPIE-INT SOC OPTICAL ENGINEERING.
DOI Scopus1
2012 Kennedy, K., Kennedy, B., McLaughlin, R., & Sampson, D. (2012). A new method of optical biopsy: Demonstration of mechanical contrast in deep tissue using an optical coherence elastography needle probe. In Proceedings of SPIE - The International Society for Optical Engineering Vol. 8351 (pp. 5 pages). Sydney, NSW, Australia: SPIE-INT SOC OPTICAL ENGINEERING.
DOI
2012 Yang, X., Lorenser, D., Kirk, R., Pinniger, G., Grounds, M., McLaughlin, R., & Sampson, D. (2012). 3D imaging of internal structures of skeletal muscle with an ultrathin side-viewing optical needle probe. In NEUROMUSCULAR DISORDERS Vol. 22 (pp. 825). Perth, AUSTRALIA: PERGAMON-ELSEVIER SCIENCE LTD.
DOI
2011 Sampson, D. D., Quirk, B. C., Curatolo, A., Scolaro, L., Kirk, R. W., Lorenser, D., . . . McLaughlin, R. A. (2011). Microscope-in-a-needle technology for deep-tissue 3D imaging. In 2011 ICO International Conference on Information Photonics, IP 2011 (pp. 2 pages). Ottawa, ON, Canada.
DOI Scopus3
2011 Kirk, R., McLaughlin, R., Quirk, B., Curatolo, A., & Sampson, D. (2011). 3D visualization of tissue microstructures using optical coherence tomography needle probes. In W. Bock, J. Albert, & X. Bao (Eds.), Proceedings of SPIE - The International Society for Optical Engineering Vol. 7753 (pp. 4 pages). Ottawa, CANADA: SPIE-INT SOC OPTICAL ENGINEERING.
DOI Scopus1
2011 Yang, X., McLaughlin, R., Lorenser, D., Kirk, R., Noble, P., & Sampson, D. (2011). In situ 3D imaging of alveoli with a 30 gauge side-facing optical needle probe. In Proceedings of the 2011 7th International Conference on Intelligent Sensors, Sensor Networks and Information Processing, ISSNIP 2011 (pp. 68-72).
DOI
2010 Liew, Y., McLaughlin, R., Curatolo, A., & Sampson, D. (2010). Assessment and correction of imaging artifacts in skin imaging using fibre-based optical coherence tomography. In 35th Australian Conference on Optical Fibre Technology, ACOFT 2010.
2010 Liew, Y., Ward, S., McLaughlin, R., Wood, F., Palmer, L., & Sampson, D. (2010). VISUALIZATION OF SUB-SURFACE STRUCTURES IN SCAR TISSUE USING OPTICAL COHERENCE TOMOGRAPHY. In WOUND REPAIR AND REGENERATION Vol. 18 (pp. A67). WILEY-BLACKWELL.
2009 Williamson, J., Armstrong, J., McLaughlin, R., Sampson, D., Regli, A., Walsh, J., . . . Eastwood, P. (2009). Regional Airway Compliance in Asthma Measured Using Anatomical Optical Coherence Tomography. In AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Vol. 179 (pp. 1 page). AMER THORACIC SOC.
2009 McLaughlin, R., Scolaro, L., Klyen, B., Hamza, S., Robbins, P., Saunders, C., & Sampson, D. (2009). Lymph node micro-architecture can be imaged using optical coherence tomography. In CANCER RESEARCH Vol. 69 (pp. 102S). San Antonio, TX: AMER ASSOC CANCER RESEARCH.
2009 McLaughlin, R., Scolaro, L., Robbins, P., Saunders, C., Jacques, S., & Sampson, D. (2009). Mapping tissue optical attenuation to identify cancer using optical coherence tomography. In Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) Vol. 5762 LNCS (pp. 657-664).
DOI Scopus4
2009 McLaughlin, R., Williamson, J., Curatolo, A., Baker, V., Hillman, D., Eastwood, P., & Sampson, D. (2009). In vivo 4D imaging of the human lower airway using anatomical optical coherence tomography. In Proceedings of SPIE - The International Society for Optical Engineering Vol. 7503.
DOI
2008 McLaughlin, R., Armstrong, J., Becker, S., Walsh, J., Kirkness, J., Jain, A., . . . Sampson, D. (2008). Respiratory gating of endoscopic OCT images of the upper airway. In D. Sampson, S. Collins, K. Oh, & R. Yamauchi (Eds.), Proceedings of SPIE - The International Society for Optical Engineering Vol. 7004 (pp. 4 pages). Perth, AUSTRALIA: SPIE-INT SOC OPTICAL ENGINEERING.
DOI
2008 Armstrong, J., Becker, S., McLaughlin, R., Leigh, M., Williamson, J., Walsh, J., . . . Sampson, D. (2008). Anatomical optical coherence tomography: A safe and effective tool for quantitative long-term monitoring of upper airway size and shape. In N. Kollias, B. Choi, H. Zeng, R. Malek, B. Wong, J. Ilgner, . . . S. Madsen (Eds.), Progress in Biomedical Optics and Imaging - Proceedings of SPIE Vol. 6842 (pp. 16 pages). San Jose, CA: SPIE-INT SOC OPTICAL ENGINEERING.
DOI Scopus4
2008 McLaughlin, R., Scolaro, L., Klyen, B., Hamza, S., Robbins, P., Saunders, C., & Sampson, D. (2008). Can normal lymph node architecture be characterised by optical coherence tomography?. In A. Podoleanu (Ed.), Proceedings of SPIE - The International Society for Optical Engineering Vol. 7139 (pp. 3 pages). Canterbury, ENGLAND: SPIE-INT SOC OPTICAL ENGINEERING.

Conference Items

Year Citation
2012 Chin, L., Xiaojie, Y., McLaughlin, R., Klyen, B., Radley-Crabb, H., Pinniger, G., . . . Sampson, D. (2012). Identification of muscle necrosis in mdx mice using optical birefringence imaging. Poster session presented at the meeting of NEUROMUSCULAR DISORDERS. Perth, AUSTRALIA: PERGAMON-ELSEVIER SCIENCE LTD.
DOI
Grants: TOTAL: $5million
$1,000,000     
 

2016-2019 South Australian Premier’s Research and Industry Fund Fellowship

(McLaughlin)

$482,200

2016-2018 ARC Discovery Grant (DP160104175)

“Visualising vascular adaptation at the micro-scale in humans”

(Green, McLaughlin)

$45,000  

2016 Photonics Catalyst Program, South Australian Govt.

“Image-guided surgery for safer and faster glaucoma treatment”

(McLaughlin, Casson, Previn)

$47,500  

UWA NHMRC Equipment Grant, “Philips Premium Portable CX50 Ultrasound System”

(Noble, Pillow, Gill, Laing, Nowak, McLaughlin, Kennedy, Hodgetts, Pinniger)

$355,100 

2015-2017 ARC Discovery Grant (DP150104660)

“Quantitative multi-modal optical imaging of deep tissue – a new window onto disease”

(McLaughlin)

$16,500          
 

UWA Research Collaboration Award 2015-2016

(McLaughlin)

$5,000      

SPIE Education Outreach Grant 2015

(McLaughlin)

$16,645    

2015 Medical and Health Research Infrastructure Fund (MHRIF), Round 18, Dept. Health.

(McLaughlin)

$726,676        
 

2014-2016 Chevron Australia / Fiona Wood Foundation

“Measuring airway capacity using optical coherence tomography”

(McLaughlin, Sampson)

$64,000    

2015 Intuitive Surgical Technology Research Grant (San Francisco, USA),

“Smart biopsy needles for real-time tissue assessment in lung cancer”

(McLaughlin, Sampson)

$25,000    

2015 Breast Cancer Research Centre WA (BCRC_WA 201406),

“Fluorescent biomarkers for improved breast cancer surgery”

(McLaughlin, Fuller)

$317,111        
 

2014-2016 NHMRC Development Grant (APP1076050),

“Development of microscope-in-a-needle devices for improved clinical diagnostics”

(McLaughlin, Sampson, Noble, Yeoh, Olynyk)

$50,000    

2014 Commercialisation Australia (CAU06334), Department of Industry, Innovation, Science, Research and Tertiary Education (DIISRTE)

“Business plan for microscope-in-a-needle imaging technology”

(McLaughlin, Sampson)

$13,407          
 

2014 Medical and Health Research Infrastructure Fund (MHRIF), Round 17, Dept. Health.

(McLaughlin)

$15,000 

2013 UWA Research Collaboration Award

“The next generation microscope-in-a-needle: Fluorescence + optical coherence tomography to find cancer”

(McLaughlin, Boudoux)

$99,537  

2013 Cancer Council WA Research Project Grant (ID 1057820),

“Intra-operative assessment of lymph node metastasis in breast cancer with optical imaging”

(McLaughlin, Saunders, Sampson)

$20,000 

2013 UWA Faculty of Engineering, Computing and Mathematics

Research Development Grants,

“Optical coherence tomography for quantitative assessment of burn scars”

(McLaughlin)

$98,551          
 

2012 Cancer Council WA Research Project Grant (ID 1052459),

“Pre-operative assessment of neoadjuvant therapy for breast cancer using optical

coherence tomography”

(McLaughlin, Saunders, Sampson)

$15,000   

2012 Royal Perth Hospital Medical Research Foundation,

“Early detection of pathological scarring using 3D optical imaging”

(McLaughlin, Wood, Kennedy, Sampson)

$539,685        
 

2012-2014 NHMRC Development Grant (APP1038871)

“Development of a new surgical-guidance tool for intra-operative tumour margin assessment in breast cancer”

(McLaughlin, Saunders, Sampson)

$200,000    

2012 National Breast Cancer Foundation Novel Concept Award,

“A new tool for intra-operative tumour margin assessment”.

(McLaughlin, Saunders, Sampson, Kennedy)

$300,000    

2011-2013 Cancer Council WA Research Fellowship

“Improved intra-operative breast cancer imaging with OCT”

(McLaughlin)

$25,760          
 

2010 UWA Safety Net Award,

(McLaughlin)

 

$21,411    

2010 Perpetual Ltd., “Better imaging to improve cancer surgery”

(McLaughlin, Kennedy, Saunders, Sampson)

$90,000          
 

2009 Perpetual Ltd., “A new breast cancer imaging probe: combining ultrasound with optical biopsy”.

(McLaughlin, Saunders, Sampson)

$198,640   

2008 National Breast Cancer Foundation Novel Concept Award,

“Steps towards an in vivo optical biopsy: Assessing lymph node metastasis using Optical Coherence Tomography”.

(McLaughlin, Saunders, Sampson)

$22,000   

2008 UWA Research Grants Scheme, “Improved Breast Cancer Surgery with Optical Imaging”.

(McLaughlin)

$267,029 

2007 Raine Medical Research Foundation, “Bringing Optical Imaging into clinical practice for breast cancer and breathing disorders”.

(McLaughlin)

 

Position
Chair of Biophotonics
Phone
83139942
Campus
North Terrace
Building
The Braggs Buidling, floor 3
Room Number
3 17
Org Unit
Adelaide Medical School

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