Dr Richard Le Leu

School of Psychology

College of Education, Behavioural and Social Science


Year Citation
2025 Choo, J. M., Kang, W. X., Le Leu, R., Manning, S. K., Elms, L., Watson, N., . . . Meade, A. (2025). The capacity of gastrointestinal microbiota in kidney transplant recipients to ferment prebiotic starch. Journal of Nephrology, 38(9), 1-6.
DOI
2024 Tarca, B., Jesudason, S., Wycherley, T. P., Le Leu, R., Ovenden, M., Meade, A., . . . Ferrar, K. E. (2024). Ecological momentary assessment to explore fatigue, mood, and physical activity levels in people receiving peritoneal dialysis. Kidney International Reports, 9(3), 601-610.
DOI Scopus6 WoS6 Europe PMC5
2024 Lunardi, L. E., K. Le Leu, R., Matricciani, L. A., Xu, Q., Britton, A., Jesudason, S., & Bennett, P. N. (2024). Patient activation in advanced chronic kidney disease: a cross-sectional study. Journal of Nephrology, 37(2), 343-352.
DOI Scopus11 WoS10 Europe PMC11
2024 Zhang, J., Le Leu, R. K., Xu, Q., & Bennett, P. (2024). The futility of post-haemodialysis blood glucose levels: A retrospective cohort study. Journal of Renal Care, 50(4), 323-329.
DOI Scopus1 WoS1 Europe PMC1
2023 Le Leu, R., Bennett, P. N., Dansie, K., Shanahan, L., Chur-Hansen, A., Collins, K. L., . . . Jesudason, S. (2023). Changes in symptom burden in the first 6 months after dialysis commencement: a prospective longitudinal observational cohort study. Journal of Nephrology, 36(5), 1485-1488.
DOI Europe PMC1
2023 Lunardi, L. E., Hill, K., Xu, Q., Le Leu, R., & Bennett, P. N. (2023). The effectiveness of patient activation interventions in adults with chronic kidney disease: a systematic review and meta-analysis. Worldviews on Evidence Based Nursing, 20(3), 238-258.
DOI Scopus21 WoS18 Europe PMC13
2023 Welke, S., Duncanson, E., Bollen, C., Britton, A., Donnelly, F., Faull, R., . . . Jesudason, S. (2023). The impact on patients of the tertiary-primary healthcare interface in kidney failure: a qualitative study.. Journal of nephrology, 36(7), 2023-2035.
DOI Scopus1 WoS1
2023 Duncanson, E. L., Chur-Hansen, A., Le Leu, R. K., Macauley, L., Burke, A. L. J., Donnelly, F. F., . . . Jesudason, S. (2023). Dialysis Needle-Related Distress: Patient Perspectives on Identification, Prevention, and Management. Kidney International Reports, 8(12), 2625-2634.
DOI Scopus7 WoS5 Europe PMC5
2023 Duncanson, E., Le Leu, R. K., Chur-Hansen, A., Masotti, T., Collins, K. L., Burke, A. L. J., . . . Jesudason, S. (2023). Nephrology nurses' perspectives working with patients experiencing needle-related distress.. J Ren Care, 50(3), 241-251.
DOI Scopus4 WoS3 Europe PMC4
2023 Radisic, G., Leu, R. L., Donnelly, F., Duncanson, E., Collins, K. L., Burke, A. L. J., . . . Jesudason, S. (2023). How can nurses support patients on hemodialysis who experience needle fear? An online educational intervention for nephrology nurses. Nephrology nursing journal : journal of the American Nephrology Nurses' Association, 50(5), 423-428.
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2022 Radisic, G., Duncanson, E., Le Leu, R., Collins, K. L., Burke, A. L. J., Turner, J. K., . . . Jesudason, S. (2022). Improving management of needle distress during the journey to dialysis through psychological education and training—the INJECT study feasibility pilot protocol. Pilot and Feasibility Studies, 8(1), 28-1-28-10.
DOI Scopus9 WoS9 Europe PMC7
2021 Tarca, B., Jesudason, S., Le Leu, R., Ovenden, M., Borlace, M., Meade, A., . . . Ferrar, K. E. (2021). Ecological momentary assessment to explore fatigue, mood and physical activity levels in people receiving peritoneal dialysis: a study protocol. Peritoneal Dialysis International, 41(5), 502-508.
DOI Scopus4 WoS4 Europe PMC3
2021 Meade, A., Le Leu, R., Watson, N., Jesudason, S., Clayton, P., Faull, R., . . . Trimingham, C. (2021). Gastrointestinal symptom burden and dietary intake in patients with chronic kidney disease. Journal of Renal Care, 47(4), 234-241.
DOI Scopus3 WoS3 Europe PMC2
2021 Duncanson, E., Le Leu, R. K., Shanahan, L., Macauley, L., Bennett, P. N., Weichula, R., . . . Jesudason, S. (2021). The prevalence and evidence-based management of needle fear in adults with chronic disease: A scoping review. PLoS One, 16(6), e0253048-1-e0253048-16.
DOI Scopus64 WoS56 Europe PMC46
2021 Hill, K., Xu, Q., Jaensch, A., Esterman, A., Le Leu, R., Childs, J., . . . Jesudason, S. (2021). "Outcomes of arteriovenous fistulae cannulation in the first 6 weeks of use: a retrospective multicenter observational study". Journal of Vascular Access, 22(5), 726-732.
DOI Scopus9 WoS8 Europe PMC7
2020 Gutman, T., Tong, A., Howell, M., Dansie, K., Hawley, C. M., Craig, J. C., . . . Better Evidence and Translation in Chronic Kidney Disease (BEAT-CKD) Workshop Investigators. (2020). Principles and strategies for involving patients in research in chronic kidney disease: report from national workshops. Nephrology Dialysis Transplantation, 35(9), 1585-1594.
DOI Scopus20 WoS19 Europe PMC16
2020 Lunardi, L., Hill, K., Crail, S., Esterman, A., Le Leu, R., & Drummond, C. (2020). 'Supportive and Palliative Care Indicators Tool (SPICT) improves renal nurses' confidence in recognising patients approaching end of life'. BMJ Supportive & Palliative Care, 14(e1), e784-e789.
DOI Scopus12 WoS10 Europe PMC10
2020 Hill, K. E., Sharp, R., Childs, J., Esterman, A., Le Leu, R., Juneja, R., & Jesudason, S. (2020). Cannulation practices at haemodialysis initiation via an arteriovenous fistula or arteriovenous graft. Journal of vascular access, 21(5), 573-581.
DOI Scopus8 WoS5 Europe PMC4
2019 Shanahan, L., Le Leu, R., Whittington, T., Biddle, A., McDonald, S., Bennett, P., & Jesudason, S. (2019). Needle fear: A point prevalence survey of dialysis patients. Hemodialysis International, 23(3), 285-286.
DOI Scopus9 WoS9 Europe PMC7
2018 Jalleh, R., Basu, G., Le Leu, R., & Jesudason, S. (2018). Denosumab-Induced Severe Hypocalcaemia in Chronic Kidney Disease.. Case reports in nephrology, 2018, 7384763.
DOI Europe PMC19
2018 Zuvela, J., Trimingham, C., Le Leu, R., Faull, R., Clayton, P., Jesudason, S., & Meade, A. (2018). Gastrointestinal symptoms in patients receiving dialysis: A systematic review. Nephrology, 23(8), 718-727.
DOI Scopus79 WoS73 Europe PMC60
2018 Trimingham, C., McDonald, S., Dansie, K., Jesudason, S., Faull, R., Clayton, P., . . . Meade, A. (2018). Bowel health in chronic kidney disease: Patient perceptions differ from clinical definitions. Journal of Renal Care, 44(2), 65-72.
DOI Scopus8 WoS6 Europe PMC5
2018 Nurdin, S. U., Le Leu, R. K., Aburto-Medina, A., Young, G. P., Stangoulis, J. C. R., Ball, A. S., & Abbott, C. A. (2018). Effects of dietary fibre from the traditional Indonesian food, green cincau (Premna oblongifolia merr.) on preneoplastic lesions and short chain fatty acid production in an azoxymethane rat model of colon cancer. International Journal of Molecular Sciences, 19(9), 18 pages.
DOI Scopus10 WoS9 Europe PMC4
2018 Wang, K., Jin, X., Li, Q., Sawaya, A. C. H. F., Le Leu, R. K., Conlon, M. A., . . . Hu, F. (2018). Propolis from Different Geographic Origins Decreases Intestinal Inflammation and Bacteroides spp. Populations in a Model of DSS-Induced Colitis. Molecular Nutrition and Food Research, 62(17), 11 pages.
DOI Scopus191 WoS181 Europe PMC140
2018 Esmaeelian, B., Benkendorff, K., Le Leu, R. K., & Abbott, C. A. (2018). Simultaneous Assessment of the Efficacy and Toxicity of Marine Mollusc–Derived Brominated Indoles in an In Vivo Model for Early Stage Colon Cancer. Integrative Cancer Therapies, 17(2), 248-262.
DOI Scopus8 WoS7 Europe PMC8
2017 Nurdin, S. U., Le Leu, R. K., Young, G. P., Stangoulis, J. C. R., Christophersen, C. T., & Abbott, C. A. (2017). Analysis of the anti-cancer effects of cincau extract (Premna oblongifolia merr) and other types of non- digestible fibre using faecal fermentation supernatants and Caco-2 cells as a model of the human colon. Nutrients, 9(4), 14 pages.
DOI Scopus13 WoS9 Europe PMC6
2017 Wang, K., Jin, X., You, M., Tian, W., Leu, R. K. L., Topping, D. L., . . . Hu, F. (2017). Dietary propolis ameliorates dextran sulfate sodium-induced colitis and modulates the gut microbiota in rats fed a western diet. Nutrients, 9(8), 13 pages.
DOI Scopus62 WoS61 Europe PMC53
2017 Zuvela, J., Meade, A., Trimingham, C., Jesudason, S., & Leu, R. L. (2017). GASTROINTESTINAL SYMPTOMS IN PATIENTS RECEIVING DIALYSIS: A SYSTEMATIC REVIEW. NEPHROLOGY, 22, 82.
2016 Hu, Y., Le Leu, R., Christophersen, C., Somashekar, R., Conlon, M., Meng, X., . . . Young, G. (2016). Manipulation of the gut microbiota using resistant starch is associated with protection against colitis-associated colorectal cancer in rats. Carcinogenesis, 37(4), 366-375.
DOI Scopus152 WoS138 Europe PMC121
2016 Hu, Y., McIntosh, G. H., Le Leu, R. K., Somashekar, R., Meng, X. Q., Gopalsamy, G., . . . Young, G. P. (2016). Supplementation with Brazil nuts and green tea extract regulates targeted biomarkers related to colorectal cancer risk in humans. British Journal of Nutrition, 116(11), 1901-1911.
DOI Scopus61 WoS51 Europe PMC41
2016 Le Leu, R., Scherer, B., Mano, M., Winter, J., Lannagan, T., Head, R., . . . Clarke, J. (2016). Dietary butyrylated high-amylose starch reduces azoxymethane-induced colonic O⁶ -methylguanine adducts in rats as measured by immunohistochemistry and high-pressure liquid chromatography. Nutrition Research, 36(9), 982-988.
DOI Scopus9 WoS9 Europe PMC9
2015 Conlon, M. A., Bird, A. R., Clarke, J. M., Le Leu, R. K., Christophersen, C. T., Lockett, T. J., & Topping, D. L. (2015). Lowering of large bowel butyrate levels in healthy populations is unlikely to be beneficial. Journal of Nutrition, 145(5), 1030-1031.
DOI Scopus9 WoS7 Europe PMC7
2015 Le Leu, R., Winter, J., Christophersen, C., Young, G., Humphreys, K., Hu, Y., . . . Conlon, M. (2015). Butyrylated starch intake can prevent red meat-induced O⁶-methyl-2-deoxyguanosine adducts in human rectal tissue: a randomised clinical trial. British Journal of Nutrition, 114(2), 220-230.
DOI Scopus131 WoS119 Europe PMC109
2015 Le Leu, R. K., Conlon, M. A., Bird, A. R., & Clarke, J. M. (2015). Housing experimental rats in solid-based cages with digestible bedding may confound outcomes of nutritional studies. Journal of the Science of Food and Agriculture, 95(10), 2155-2158.
DOI Scopus10 WoS10 Europe PMC9
2015 Winter, J., Hu, Y., Young, G., Kohonen-Corish, M., & Le Leu, R. (2015). Role of red meat and resistant starch in promutagenic adduct formation, MGMT repair, thymic lymphoma and intestinal tumourigenesis in Msh2-deficient mice. Journal of Nutrigenetics and Nutrigenomics, 7(4-6), 299-313.
DOI Scopus4 WoS4 Europe PMC3
2014 Winter, J., Young, G., Hu, Y., Gratz, S., Conlon, M., & Le Leu, R. (2014). Accumulation of promutagenic DNA adducts in the mouse distal colon after consumption of heme does not induce colonic neoplasms in the western diet model of spontaneous colorectal cancer. Molecular Nutrition and Food Research, 58(3), 550-558.
DOI Scopus21 WoS16 Europe PMC13
2014 Esmaeelian, B., Abbott, C. A., Le Leu, R. K., & Benkendorff, K. (2014). 6-Bromoisatin found in muricid mollusc extracts inhibits colon cancer cell proliferation and induces apoptosis, preventing early stage tumor formation in a colorectal cancer rodent model. Marine Drugs, 12(1), 17-35.
DOI Scopus42 WoS43 Europe PMC34
2014 Humphreys, K., Conlon, M., Young, G., Topping, D., Hu, Y., Winter, J., . . . Le Leu, R. (2014). Dietary manipulation of oncogenic microRNA expression in human rectal mucosa: a randomized trial. Cancer Prevention Research, 7(8), 786-795.
DOI Scopus105 WoS88 Europe PMC76
2013 Martin, J., Young, G., Le Leu, R., & Hu, Y. (2013). Comparing the effects of COX and Non-COX-inhibiting NSAIDs on enhancement of apoptosis and inhibition of aberrant crypt foci formation in a rat colorectal cancer model. Anticancer Research, 33(9), 3581-3588.
Scopus6 WoS6 Europe PMC4
2013 Nyskohus, L., Watson, A., Margison, G., Le Leu, R., Kim, S., Lockett, T., . . . Hu, Y. (2013). Repair and removal of azoxymethane-induced O⁶-methylguanine in rat colon by O⁶-methylguanine DNA methyltransferase and apoptosis. Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 758(1-2), 80-86.
DOI Scopus21 WoS20 Europe PMC19
2013 Hu, Y., McIntosh, G., Le Leu, R., Nyskohus, L., Woodman, R., & Young, G. (2013). Combination of selenium and green tea improves the efficacy of chemoprevention in a rat colorectal cancer model by modulating genetic and epigenetic biomarkers. PLoS One, 8(5), e64362-1-e64362-12.
DOI Scopus48 WoS39 Europe PMC30
2013 Westley, C. B., Benkendorff, K., McIver, C. M., Le Leu, R. K., & Abbott, C. A. (2013). Gastrointestinal and hepatotoxicity assessment of an anticancer extract from muricid molluscs. Evidence Based Complementary and Alternative Medicine, 2013, 12 pages.
DOI Scopus11 WoS13 Europe PMC11
2013 Le Leu, R., Young, G., Hu, Y., Winter, J., & Conlon, M. (2013). Dietary red meat aggravates dextran sulfate sodium-induced colitis in mice whereas resistant starch attenuates inflammation. Digestive Diseases and Sciences, 58(12), 3475-3482.
DOI Scopus77 WoS62 Europe PMC59
2013 Humphreys, K. J., Cobiac, L., Le Leu, R. K., Van der Hoek, M. B., & Michael, M. Z. (2013). Histone deacetylase inhibition in colorectal cancer cells reveals competing roles for members of the oncogenic miR-17-92 cluster. Molecular Carcinogenesis, 52(6), 459-474.
DOI Scopus102 WoS90 Europe PMC79
2011 Hu, Y., McIntosh, G. H., Le Leu, R. K., Upton, J. M., Oodman, R. J., & Young, G. P. (2011). The influence of selenium-enriched milk proteins and selenium yeast on plasma selenium levels and rectal selenoprotein gene expression in human subjects. British Journal of Nutrition, 106(4), 572-582.
DOI Scopus25 WoS18 Europe PMC18
2011 Worthley, D., Whitehall, V., Le Leu, R., Irahara, N., Buttenshaw, R., Mallitt, K., . . . Leggett, B. (2011). DNA methylation in the rectal mucosa is associated with crypt proliferation and fecal short-chain fatty acids. Digestive Diseases and Sciences, 56(2), 387-396.
DOI Scopus23 WoS22 Europe PMC22
2011 Winter, J., Nyskohus, L., Young, G., Hu, Y., Conlon, M., Bird, A., . . . Le Leu, R. (2011). Inhibition by resistant starch of red meat-induced promutagenic adducts in mouse colon. Cancer Prevention Research, 4(11), 1920-1928.
DOI Scopus66 WoS61 Europe PMC52
2010 Worthley, D., Whitehall, V., Buttenshaw, R., Irahara, N., Greco, S., Ramsnes, I., . . . Leggett, B. (2010). DNA methylation within the normal colorectal mucosa is associated with pathway-specific predisposition to cancer. Oncogene, 29(11), 1653-1662.
DOI Scopus96 WoS91 Europe PMC88
2010 Westley, C. B., McIver, C. M., Abbott, C. A., Le Leu, R. K., & Benkendorff, K. (2010). Enhanced acute apoptotic response to azoxymethane-induced DNA damage in the rodent colonic epithelium by Tyrian purple precursors: A potential colorectal cancer chemopreventative. Cancer Biology and Therapy, 9(5), 371-379.
DOI Scopus30 WoS29 Europe PMC25
2010 Hu, Y., Le Leu, R. K., Nyskohus, L. S., Winter, J., & Young, G. P. (2010). Combination of selenium and green tea improves the efficacy of chemoprevention of selenium and green tea alone in a rat colon cancer model. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 25, A73-A74.
2010 Le Leu, R. K., Winter, J., Hu, Y., Nyskohus, L., Conlon, M. A., Bird, A. R., . . . Young, G. P. (2010). High dietary protein and DNA damage in the rodent colon: regulation by resistant starch. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 25, A112-A113.
2010 Le Leu, R. K., Hu, Y., Brown, I. L., Woodman, R. J., & Young, G. P. (2010). Synbiotic intervention of Bifidobacterium lactis and resistant starch protects against colorectal cancer development in rats. Carcinogenesis, 31(2), 246-251.
DOI Scopus177 WoS148 Europe PMC119
2010 Hu, Y., McIntosh, G. H., Le Leu, R. K., & Young, G. P. (2010). Selenium-enriched milk proteins and selenium yeast affect selenoprotein activity and expression differently in mouse colon. British Journal of Nutrition, 104(1), 17-23.
DOI Scopus31 WoS29 Europe PMC21
2010 Martin, J. E., Le Leu, R. K., Hu, Y., & Young, G. P. (2010). R-flurbiprofen suppresses distal nonmucin-producing colorectal tumors in azoxymethane-treated rats, without suppressing eicosanoid production. American Journal of Physiology Gastrointestinal and Liver Physiology, 298(6), G860-G864.
DOI Scopus7 WoS7 Europe PMC4
2010 Leu, R. K. L., Winter, J. M., Hu, Y., Nyskohus, L. S., Conlon, M., Bird, A. R., . . . Young, G. P. (2010). M1181 Red Meat Diets Increase the Formation of O6-Methyl-2-Deoxyguanosine Adducts in the Mouse Colon: Attenuation by Resistant Starch. Gastroenterology, 138(5), S-349.
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2009 Worthley, D. L., Whitehall, V. L., Buttenshaw, R., Mallitt, K. -A., Le Leu, R. K., Young, G. P., & Leggett, B. A. (2009). 199 DNA Methylation Throughout the Normal Human Colorectum: Evidence of An Epigenetic Field Effect. Gastroenterology, 136(5), A-37.
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2009 Hu, Y., McIntosh, G. H., Le Leu, R. K., & Young, G. P. (2009). W1958 The Influence of Selenium-Enriched Milk Proteins On Selenium Status and Colorectal Cancer Risk in Humans. Gastroenterology, 136(5), A-761.
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2009 Le Leu, R. K., Hu, Y., Brown, I. L., & Young, G. P. (2009). W1964 A Combination of Bifidobacterium Lactis and Resistant Starch Can Protect Against Colorectal Cancer Development in Rats. Gastroenterology, 136(5).
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2009 Le Leu, R. K., Hu, Y., Brown, I. L., & Young, G. P. (2009). Effect of high amylose maize starches on colonic fermentation and apoptotic response to DNA-damage in the colon of rats. Nutrition and Metabolism, 6(1), 9 pages.
DOI Scopus100 WoS87 Europe PMC68
2009 Worthley, D., Le Leu, R., Whitehall, V., Conlon, M., Christophersen, C., Belobrajdic, D., . . . Young, G. (2009). A human, double-blind, placebo-controlled, crossover trial of prebiotic, probiotic, and synbiotic supplementation: Effects on luminal, inflammatory, epigenetic, and epithelial biomarkers of colorectal cancer. American Journal of Clinical Nutrition, 90(3), 578-586.
DOI Scopus133 WoS117 Europe PMC93
2009 Worthley, D. L., Leleu, R., Whitehall, V., Conlon, M., Christophersen, C., Belobrajdic, D., . . . Young, G. (2009). A human, double-blind, placebo-controlled, cross-over trial of prebiotic, probiotic and synbiotic supplementation: effects on luminal, inflammatory, epigenetic and epithelial biomarkers of colorectal cancer. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 24, A239.
2009 Hu, Y., Le Leu, R. K., & Young, G. P. (2009). Detection of K-ras mutations in azoxymethane-induced aberrant crypt foci in mice using LNA-mediated real-time PCR clamping and mutant-specific probes. Mutation Research Genetic Toxicology and Environmental Mutagenesis, 677(1-2), 27-32.
DOI Scopus18 WoS19 Europe PMC12
2008 Worthley, D. L., Whitehall, V. L., Leleu, R., Buttenshaw, R., Young, G. P., & Leggett, B. A. (2008). DNA methylation throughout the human colorectum is associated with age, region and pathology. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 23, A206.
2008 Hu, Y., Le Leu, R. K., Belobrajdic, D., & Young, G. P. (2008). The potential of sphingomyelin as a chemopreventive agent in AOM-induced colon cancer model: Wild-type and p53+/- mice. Molecular Nutrition and Food Research, 52(5), 558-566.
DOI Scopus13 WoS12 Europe PMC12
2008 Hu, Y., McIntosh, G. H., Le Leu, R. K., Woodman, R., & Young, G. P. (2008). Suppression of colorectal oncogenesis by selenium-enriched milk proteins: Apoptosis and K-ras mutations. Cancer Research, 68(12), 4936-4944.
DOI Scopus54 WoS45 Europe PMC33
2008 Hu, Y., McIntosh, G. H., Le Leu, R. K., & Young, G. P. (2008). W1105 Suppression of Colon Cancer By Selenium-Enriched Milk Proteins: Enhanced Apoptotic Response to Carcinogen Is Associated with Reduction in Frequency of K-RAS Mutations. Gastroenterology, 134(4), A-634.
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2007 Nutrition (2007). Journal of Gastroenterology and Hepatology, 22(s3).
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2007 Hu, Y., Le Leu, R. K., & Young, G. P. (2007). Defective acute apoptotic response to genotoxic carcinogen in small intestine of APCMin/+ mice is restored by sulindac. Cancer Letters, 248(2), 234-244.
DOI Scopus8 WoS8 Europe PMC7
2007 Le Leu, R. K., & Young, G. P. (2007). Fermentation of starch and protein in the colon: Implications for genomic instability. Cancer Biology and Therapy, 6(2), 259-260.
DOI Scopus17 WoS14 Europe PMC11
2007 Le Leu, R., Brown, I., Hu, Y., Morita, T., Esterman, A. J., & Young, G. (2007). Effect of dietary resistant starch and protein on colonic fermentation and intestinal tumourigenesis in rats. Carcinogenesis, 28(2), 240-245.
DOI Scopus119 WoS99 Europe PMC75
2007 Le Leu, R., Brown, I., Hu, Y., Esterman, A. J., & Young, G. (2007). Suppression of azoxymethane-induced colon cancer development in rats by dietary resistant starch. Cancer Biology and Therapy, 6(10), 1621-1626.
DOI Scopus58 WoS51 Europe PMC40
2007 Benassi-Evans, B., Le Leu, R., Bird, A., Clifton, P., & Fenech, M. (2007). Cytokinesis-block micronucleus cytome assays for the determination of genotoxicity and cytotoxicity of cecal water in rats and fecal water in humans. Cancer Epidemiology Biomarkers & Prevention, 16(12), 2676-2680.
DOI Scopus13 WoS10 Europe PMC7
2005 Young, G. P., Hu, Y., Le Leu, R. K., & Nyskohus, L. (2005). Dietary fibre and colorectal cancer: A model for environment - Gene interactions. Molecular Nutrition and Food Research, 49(6), 571-584.
DOI Scopus138 WoS120 Europe PMC91
2005 Hu, Y., Le Leu, R. K., & Young, G. P. (2005). Sulindac corrects defective apoptosis and suppresses azoxymethane-induced colonic oncogenesis in p53 knockout mice. International Journal of Cancer, 116(6), 870-875.
DOI Scopus19 WoS19 Europe PMC15
2005 le leu, R., Brown, I., Hu, Y., Bird, A., Jackson, M., Esterman, A. J., & Young, G. (2005). A synbiotic combination of resistant starch and Bifidobacterium lactis facilitates apoptotic deletion of carcinogen-damaged cells in rat colon. Journal of Nutrition, 135(5), 996-1001.
DOI Scopus196 WoS157 Europe PMC96
2005 Hu, Y., Le Leu, R. K., & Young, G. P. (2005). Absence of acute apoptotic response to genotoxic carcinogens in p53-deficient mice is associated with increased susceptibility to azoxymethane-induced colon tumours. International Journal of Cancer, 115(4), 561-567.
DOI Scopus32 WoS30 Europe PMC27
2004 Young, G. P., & Le Leu, R. K. (2004). Resistant starch and colorectal neoplasia. Journal of AOAC International, 87(3), 775-786.
DOI Scopus39 WoS29 Europe PMC16
2003 Le Leu, R. K., Brown, I. L., Hu, Y., & Young, G. P. (2003). Effect of resistant starch on genotoxin-induced apoptosis, colonic epithelium, and lumenal contents in rats. Carcinogenesis, 24(8), 1347-1352.
DOI Scopus83 WoS73 Europe PMC51
2002 Le Leu, R. K., Hu, Y., & Young, G. P. (2002). Effects of resistant starch and nonstarch polysaccharides on colonic luminal environment and genotoxin-induced apoptosis in the rat. Carcinogenesis, 23(5), 713-719.
DOI Scopus65 WoS60 Europe PMC49
2002 Hu, Y., Martin, J., Le Leu, R., & Young, G. P. (2002). The colonic response to genotoxic carcinogens in the rat: Regulation by dietary fibre. Carcinogenesis, 23(7), 1131-1137.
DOI Scopus47 WoS48 Europe PMC32
2002 Young, G. P., & Le Leu, R. K. (2002). Preventing cancer: dietary lifestyle or clinical intervention?. Asia Pacific Journal of Clinical Nutrition, 11 Suppl 3(s3), S618-S631.
DOI Scopus23 WoS17 Europe PMC7
2001 McIntosh, G. H., & Le Leu, R. K. (2001). The influence of dietary proteins on colon cancer risk. Nutrition Research, 21(7), 1053-1066.
DOI Scopus44 WoS38 Europe PMC21
2001 Martin, J. E., Young, G. P., James, R., Hu, Y., & Leu, R. L. (2001). Lack of interaction of sulindac and n-3 fatty acids in their effects on colo-rectal tumourigenesis. Gastroenterology, 120(5), A253.
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2000 Le Leu, R. K., Young, G. P., & McIntosh, G. H. (2000). Folate deficiency reduces the development of colorectal cancer in rats. Carcinogenesis, 21(12), 2261-2265.
DOI Scopus79 WoS72 Europe PMC59
2000 Le Leu, R. K., Young, G. P., & McIntosh, G. H. (2000). Folate deficiency diminishes the occurrence of aberrant crypt foci in the rat colon but does not alter global DNA methylation status. Journal of Gastroenterology and Hepatology Australia, 15(10), 1158-1164.
DOI Scopus38 WoS34 Europe PMC31
1998 Le Leu, R. K., McIntosh, G. H., & Young, G. P. (1998). Ability of endogenous folate from soy protein isolate to maintain plasma homocysteine and hepatic DNA methylation during methyl group depletion in rats. Journal of Nutritional Science and Vitaminology, 44(3), 457-464.
DOI Scopus9 WoS8 Europe PMC4
1996 Mcintosh, G. H., Le Leu, R. K., Royle, P. J., & Young, G. P. (1996). A comparative study of the influence of differing barley brans on DMH-induced intestinal tumours in male Sprague-Dawley rats. Journal of Gastroenterology and Hepatology Australia, 11(2), 113-119.
DOI Scopus47 WoS38 Europe PMC27
1996 Noakes, M., Clifton, P. M., Nestel, P. J., Le Leu, R., & McIntosh, G. (1996). Effect of high-amylose starch and oat bran on metabolic variables and bowel function in subjects with hypertriglyceridemia. American Journal of Clinical Nutrition, 64(6), 944-951.
DOI Scopus154 WoS139 Europe PMC97
1995 McIntosh, G. H., Regester, G. O., Le Leu, R. K., Royle, P. J., & Smithers, G. W. (1995). Dairy proteins protect against dimethylhydrazine-induced intestinal cancers in rats. Journal of Nutrition, 125(4), 809-816.
DOI Scopus200 WoS176 Europe PMC94
1993 MCINTOSH, G. H., LELEU, R. K., KERRY, A., & GOLDRING, M. (1993). BARLEY-GRAIN FOR HUMAN FOOD USE. FOOD AUSTRALIA, 45(8), 392-394.
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1991 Hayball, P. J., Nation, R. L., Bochner, F., & Le Leu, R. K. (1991). Enantiospecific analysis of ketoprofen in plasma by high-performance liquid chromatography. Journal of Chromatography: Biomedical Applications, 507(2), 446-452.
DOI Scopus26 WoS26 Europe PMC13

Year Citation
2012 Roediger, W., Le Leu, R., & Jones, T. (2012). DIVERSION COLITIS TREATMENT WITH RAPIDLY FERMENTABLE FIBRE-SUPPOSITORIES. In GUT Vol. 61 (pp. A93). B M J PUBLISHING GROUP.
DOI
2011 Le Leu, R., Winter, J., Hu, Y., Nyskohus, L., Conlon, M., Bird, A., . . . Young, G. (2011). Inhibition by Resistant Starch of Red Meat-Induced Promutagenic Adducts in Mouse Colon.. In ENVIRONMENTAL AND MOLECULAR MUTAGENESIS Vol. 52 (pp. S71). Montreal, CANADA: WILEY-BLACKWELL.
2011 Hu, Y., Le Leu, R. K., Nyskohus, L. S., Winter, J., & Young, G. P. (2011). Combination of Selenium and Green Tea Improves the Efficacy of Chemoprevention of Selenium and Green Tea Alone in a Rat Colon Cancer Model.. In ENVIRONMENTAL AND MOLECULAR MUTAGENESIS Vol. 52 (pp. S71). Montreal, CANADA: WILEY-BLACKWELL.
2010 Le Leu, R. K., Winter, J. M., Hu, Y., Nyskohus, L. S., Conlon, M., Bird, A. R., . . . Young, G. P. (2010). Red Meat Diets Increase the Formation of O6-Methyl-2-Deoxyguanosine Adducts in the Mouse Colon: Attenuation by Resistant Starch. In GASTROENTEROLOGY Vol. 138 (pp. S349). W B SAUNDERS CO-ELSEVIER INC.
2009 Hu, Y., McIntosh, G. H., Le Leu, R. K., & Young, G. P. (2009). The Influence of Selenium-Enriched Milk Proteins On Selenium Status and Colorectal Cancer Risk in Humans. In GASTROENTEROLOGY Vol. 136 (pp. A761). Chicago, IL: W B SAUNDERS CO-ELSEVIER INC.
2009 Le Leu, R. K., Hu, Y., Brown, I. L., & Young, G. P. (2009). A Combination of Bifidobacterium Lactis and Resistant Starch Can Protect Against Colorectal Cancer Development in Rats. In GASTROENTEROLOGY Vol. 136 (pp. A762-A763). Chicago, IL: W B SAUNDERS CO-ELSEVIER INC.
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2009 Worthley, D. L., Whitehall, V. L., Buttenshaw, R., Mallitt, K. -A., Le Leu, R. K., Young, G. P., & Leggett, B. A. (2009). DNA Methylation Throughout the Normal Human Colorectum: Evidence of An Epigenetic Field Effect. In GASTROENTEROLOGY Vol. 136 (pp. A37). W B SAUNDERS CO-ELSEVIER INC.
WoS1
2008 Le Leu, R. K., Hu, Y., Brown, I. L., & Young, G. P. (2008). Synbiotic combination of bifidobacterium lactis and resistant starch can protect against colorectal cancer development. In JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Vol. 23 (pp. A209). WILEY-BLACKWELL PUBLISHING, INC.
2008 Hu, Y., Mclntosh, G. H., Le Leu, R. K., & Young, G. P. (2008). Suppression of colon cancer by selenium-enriched milk proteins: Enhanced apoptotic response to carcinogen is associated with reduction in frequency of K-RAS mutations. In GASTROENTEROLOGY Vol. 134 (pp. A634). W B SAUNDERS CO-ELSEVIER INC.
2007 Hu, Y., Leleu, R., Mcintosh, G., & Young, G. (2007). Chemopreventive effect of high selenium enriched milk protein on azoxymethanc-fiaduced colonic tumorigenesis. In GASTROENTEROLOGY Vol. 132 (pp. A439). Washington, DC: W B SAUNDERS CO-ELSEVIER INC.
2006 Le Leu, R. K., Brown, I. L., Hu, Y., & Young, G. P. (2006). Effect of undigested starch and protein on intestinal tumorigenesis. In JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Vol. 21 (pp. A346). BLACKWELL PUBLISHING.
2006 Hu, Y., Le Leu, R. K., & Young, G. P. (2006). Detection of K-ras mutation in AOM-induced colonic tumorigenesis by locked nucleic acid (LNA)-mediated PCR clamping and melting curve analysis. In JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Vol. 21 (pp. A268). BLACKWELL PUBLISHING.
2004 Hu, Y., Le Leu, R. K., & Young, G. P. (2004). Effect of sulindac on acute apoptotic response to carcinogen in p53 knockout mice. In GASTROENTEROLOGY Vol. 126 (pp. A303). New Orleans, LA: W B SAUNDERS CO.
2003 Martin, J., Leu, L., Hu, Y., & Young, G. (2003). Prevention of colorectal carcinoma in azoxymethane treated rats by non-steroidal anti-inflammatory drugs (NSAIDs) is dependent on histologic type. In GASTROENTEROLOGY Vol. 124 (pp. A604). ORLANDO, FLORIDA: W B SAUNDERS CO.
DOI
2002 Hu, Y., Le Leu, R. K., Martin, J. E., & Young, G. (2002). The acute apoptotic response in the colon to DNA damage by carcinogen is dependent on p53 but not APC. In GASTROENTEROLOGY Vol. 122 (pp. A684). W B SAUNDERS CO.
2001 Martin, J. E., Young, G. P., James, R., Hu, Y., & Le Leu, R. (2001). Lack of interaction of sulindac and n-3 fatty acids in their effects on colo-rectal tumourigenesis. In GASTROENTEROLOGY Vol. 120 (pp. A253). W B SAUNDERS CO.
DOI
2001 Le Leu, R. K., Hu, Y., & Young, G. P. (2001). Effects of resistant starch and nonstarch polysaccharides on luminal environment and AOM-induced apoptosis. In GASTROENTEROLOGY Vol. 120 (pp. A667). W B SAUNDERS CO.
DOI
1999 Le Leu, R. K., McIntosh, G. H., & Young, G. P. (1999). Effect of folate deficiency on formation of azoxy-methane-induced aberrant crypt foci in the rat colon. In GASTROENTEROLOGY Vol. 116 (pp. A449). W B SAUNDERS CO-ELSEVIER INC.
WoS1
1998 McIntosh, G. H., Royle, P. J., Le Leu, R. K., Regester, G. O., Johnson, M. A., Grinsted, R. L., . . . Smithers, G. W. (1998). Whey proteins as functional food ingredients?. In International Dairy Journal Vol. 8 (pp. 425-434). IRELAND, CORK: ELSEVIER SCI LTD.
DOI Scopus154 WoS132 Europe PMC49
1996 Noakes, M., Clifton, P. M., Nestel, P. J., LeLeu, R., & McIntosh, G. (1996). Effect of high amylose starch and oat bran on metabolic variables and bowel function in subjects with hypertriglyceridemia. In J. C. B. Miller (Ed.), PROCEEDINGS OF THE NUTRITION SOCIETY OF AUSTRALIA, VOL 20 Vol. 20 (pp. 192). SYDNEY, AUSTRALIA: NUTRITION SOC AUSTRALIA.

Year Citation
2019 Shannahan, L., Le Leu, R., Bennett, P., Chur-Hansen, A., Burke, A. L., Collins, K., . . . Jesudason, S. (2019). Patient Reported Outcome Measures Over the First Three Months of Dialysis: Interim Results from the Multidisciplinary Assessment at Dialysis Entry (MADE) Study. Poster session presented at the meeting of ISN World Congress of Nephrology. Melbourne, Victoria.
2012 Winter, J., Nyskohus, L., Young, G. P., Hu, Y., Conlon, M., Bird, A., . . . LeLeu, R. (2012). High Red Meat-Induced Promutagenic Adducts in the Mouse and Human Colon and Their Inhibition by Resistant Starch. Poster session presented at the meeting of ENVIRONMENTAL AND MOLECULAR MUTAGENESIS. Bellevue, WA: WILEY-BLACKWELL.
2012 Le Leu, R., Conlon, M., Winter, J., Humphreys, K., Michael, M., Hu, Y., . . . Young, G. (2012). Effect of high red meat intake and resistant starch in humans on risk factors for colorectal cancer. Poster session presented at the meeting of Journal of Gastroenterology and Hepatology. Adelaide, SA: Wiley.
DOI WoS2
2012 Proctor, S. J., Roediger, W., & Cummins, A. G. (2012). Regional characteristics and proposed mechanisms of mucosal adaptation in short bowel syndrome. Poster session presented at the meeting of Journal of Gastroenterology and Hepatology. Adelaide, SA: Wiley.
DOI
2012 Abimosleh, S. M., Cuong, T., Lotfollahi, Z., Penascoza, E. M., Stomaci, D. G., & Howarth, G. (2012). Emu oil maintains intestinal goblet cell numbers and reduces acute inflammation in a rat model of chemotherapy-induced mucositis. Poster session presented at the meeting of Journal of Gastroenterology and Hepatology. Adelaide, SA: Wiley.
DOI

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