Richard Le Leu

Richard Le Leu

School of Biomedicine

Faculty of Health and Medical Sciences


  • Journals

    Year Citation
    2022 Radisic, G., Duncanson, E., Le Leu, R., Collins, K. L., Burke, A. L. J., Turner, J. K., . . . Jesudason, S. (2022). Improving management of needle distress during the journey to dialysis through psychological education and training—the INJECT study feasibility pilot protocol. Pilot and Feasibility Studies, 8(1), 28.
    DOI
    2021 Tarca, B., Jesudason, S., Le Leu, R., Ovenden, M., Borlace, M., Meade, A., . . . Ferrar, K. E. (2021). Ecological momentary assessment to explore fatigue, mood and physical activity levels in people receiving peritoneal dialysis: A study protocol. Peritoneal Dialysis International, 41(5), 502-508.
    DOI
    2021 Meade, A., Le Leu, R., Watson, N., Jesudason, S., Clayton, P., Faull, R., . . . Trimingham, C. (2021). Gastrointestinal symptom burden and dietary intake in patients with chronic kidney disease. Journal of Renal Care, 47(4), 234-241.
    DOI Scopus1 WoS1
    2021 Duncanson, E., Le Leu, R. K., Shanahan, L., Macauley, L., Bennett, P. N., Weichula, R., . . . Jesudason, S. (2021). The prevalence and evidence-based management of needle fear in adults with chronic disease: A scoping review. PLOS ONE, 16(6), 1-16.
    DOI Scopus3 WoS2 Europe PMC1
    2021 Hill, K., Xu, Q., Jaensch, A., Esterman, A., Le Leu, R., Childs, J., . . . Jesudason, S. (2021). “Outcomes of arteriovenous fistulae cannulation in the first 6 weeks of use: A retrospective multicenter observational study”. Journal of Vascular Access, 22(5), 726-732.
    DOI Scopus2 WoS2 Europe PMC1
    2020 Gutman, T., Tong, A., Howell, M., Dansie, K., Hawley, C. M., Craig, J. C., . . . Better Evidence and Translation in Chronic Kidney Disease (BEAT-CKD) Workshop Investigators. (2020). Principles and strategies for involving patients in research in chronic kidney disease: report from national workshops. Nephrology Dialysis Transplantation, 35(9), 1585-1594.
    DOI Scopus9 WoS8 Europe PMC3
    2020 Lunardi, L., Hill, K., Crail, S., Esterman, A., Le Leu, R., & Drummond, C. (2020). Supportive and Palliative Care Indicators Tool (SPICT) improves renal nurses' confidence in recognising patients approaching end of life. BMJ Supportive and Palliative Care, bmjspcare-2020-002496.
    DOI Scopus3 Europe PMC1
    2020 Hill, K., Sharp, R., Childs, J., Esterman, A., Le Leu, R., Juneja, R., & Jesudason, S. (2020). Cannulation practices at haemodialysis initiation via an arteriovenous fistula or arteriovenous graft. Journal of Vascular Access, 21(5), 573-581.
    DOI Scopus2 WoS2
    2019 Shanahan, L., Le Leu, R., Whittington, T., Biddle, A., McDonald, S., Bennett, P., & Jesudason, S. (2019). Needle fear: A point prevalence survey of dialysis patients. Hemodialysis International, 23(3), 285-286.
    DOI Scopus4 WoS4 Europe PMC2
    2018 Jalleh, R., Basu, G., Le Leu, R., & Jesudason, S. (2018). Denosumab-Induced Severe Hypocalcaemia in Chronic Kidney Disease.. Case reports in nephrology, 2018, 7384763.
    DOI Europe PMC2
    2018 Zuvela, J., Trimingham, C., Le Leu, R., Faull, R., Clayton, P., Jesudason, S., & Meade, A. (2018). Gastrointestinal symptoms in patients receiving dialysis: A systematic review. Nephrology, 23(8), 718-727.
    DOI Scopus34 WoS33 Europe PMC12
    2018 Trimingham, C., McDonald, S., Dansie, K., Jesudason, S., Faull, R., Clayton, P., . . . Meade, A. (2018). Bowel health in chronic kidney disease: Patient perceptions differ from clinical definitions. Journal of Renal Care, 44(2), 65-72.
    DOI Scopus6 WoS5 Europe PMC2
    2018 Nurdin, S. U., Le Leu, R. K., Aburto-Medina, A., Young, G. P., Stangoulis, J. C. R., Ball, A. S., & Abbott, C. A. (2018). Effects of dietary fibre from the traditional Indonesian food, green cincau (Premna oblongifolia merr.) on preneoplastic lesions and short chain fatty acid production in an azoxymethane rat model of colon cancer. International Journal of Molecular Sciences, 19(9), 18 pages.
    DOI Scopus5 WoS6 Europe PMC2
    2018 Wang, K., Jin, X., Li, Q., Sawaya, A. C. H. F., Le Leu, R. K., Conlon, M. A., . . . Hu, F. (2018). Propolis from Different Geographic Origins Decreases Intestinal Inflammation and Bacteroides spp. Populations in a Model of DSS-Induced Colitis. Molecular Nutrition and Food Research, 62(17), 11 pages.
    DOI Scopus129 WoS124 Europe PMC56
    2018 Esmaeelian, B., Benkendorff, K., Le Leu, R. K., & Abbott, C. A. (2018). Simultaneous Assessment of the Efficacy and Toxicity of Marine Mollusc–Derived Brominated Indoles in an In Vivo Model for Early Stage Colon Cancer. Integrative Cancer Therapies, 17(2), 248-262.
    DOI Scopus6 WoS7 Europe PMC6
    2017 Nurdin, S. U., Le Leu, R. K., Young, G. P., Stangoulis, J. C. R., Christophersen, C. T., & Abbott, C. A. (2017). Analysis of the anti-cancer effects of cincau extract (Premna oblongifolia merr) and other types of non- digestible fibre using faecal fermentation supernatants and Caco-2 cells as a model of the human colon. Nutrients, 9(4), 14 pages.
    DOI Scopus11 WoS8 Europe PMC2
    2017 Wang, K., Jin, X., You, M., Tian, W., Leu, R. K. L., Topping, D. L., . . . Hu, F. (2017). Dietary propolis ameliorates dextran sulfate sodium-induced colitis and modulates the gut microbiota in rats fed a western diet. Nutrients, 9(8), 13 pages.
    DOI Scopus44 WoS43 Europe PMC25
    2017 Zuvela, J., Meade, A., Trimingham, C., Jesudason, S., & Leu, R. L. (2017). GASTROINTESTINAL SYMPTOMS IN PATIENTS RECEIVING DIALYSIS: A SYSTEMATIC REVIEW. NEPHROLOGY, 22, 82.
    2016 Hu, Y., Le Leu, R., Christophersen, C., Somashekar, R., Conlon, M., Meng, X., . . . Young, G. (2016). Manipulation of the gut microbiota using resistant starch is associated with protection against colitis-associated colorectal cancer in rats. Carcinogenesis, 37(4), 366-375.
    DOI Scopus90 WoS91 Europe PMC53
    2016 Hu, Y., McIntosh, G., Le Leu, R., Somashekar, R., Meng, X., Gopalsamy, G., . . . Young, G. (2016). Supplementation with Brazil nuts and green tea extract regulates targeted biomarkers related to colorectal cancer risk in humans. British Journal of Nutrition, 116(11), 1901-1911.
    DOI Scopus36 WoS30 Europe PMC13
    2016 Le Leu, R., Scherer, B., Mano, M., Winter, J., Lannagan, T., Head, R., . . . Clarke, J. (2016). Dietary butyrylated high-amylose starch reduces azoxymethane-induced colonic O⁶ -methylguanine adducts in rats as measured by immunohistochemistry and high-pressure liquid chromatography. Nutrition Research, 36(9), 982-988.
    DOI Scopus6 WoS6 Europe PMC5
    2015 Conlon, M. A., Bird, A. R., Clarke, J. M., Le Leu, R. K., Christophersen, C. T., Lockett, T. J., & Topping, D. L. (2015). Lowering of large bowel butyrate levels in healthy populations is unlikely to be beneficial. Journal of Nutrition, 145(5), 1030-1031.
    DOI Scopus5 WoS5 Europe PMC4
    2015 Le Leu, R., Winter, J., Christophersen, C., Young, G., Humphreys, K., Hu, Y., . . . Conlon, M. (2015). Butyrylated starch intake can prevent red meat-induced O⁶-methyl-2-deoxyguanosine adducts in human rectal tissue: a randomised clinical trial. British Journal of Nutrition, 114(2), 220-230.
    DOI Scopus78 WoS74 Europe PMC43
    2015 Le Leu, R. K., Conlon, M. A., Bird, A. R., & Clarke, J. M. (2015). Housing experimental rats in solid-based cages with digestible bedding may confound outcomes of nutritional studies. Journal of the Science of Food and Agriculture, 95(10), 2155-2158.
    DOI Scopus6 WoS5 Europe PMC3
    2015 Winter, J., Hu, Y., Young, G., Kohonen-Corish, M., & Le Leu, R. (2015). Role of red meat and resistant starch in promutagenic adduct formation, MGMT repair, thymic lymphoma and intestinal tumourigenesis in Msh2-deficient mice. Journal of Nutrigenetics and Nutrigenomics, 7(4-6), 299-313.
    DOI Scopus4 WoS4 Europe PMC2
    2014 Winter, J., Young, G., Hu, Y., Gratz, S., Conlon, M., & Le Leu, R. (2014). Accumulation of promutagenic DNA adducts in the mouse distal colon after consumption of heme does not induce colonic neoplasms in the western diet model of spontaneous colorectal cancer. Molecular Nutrition and Food Research, 58(3), 550-558.
    DOI Scopus18 WoS16 Europe PMC9
    2014 Esmaeelian, B., Abbott, C. A., Le Leu, R. K., & Benkendorff, K. (2014). 6-Bromoisatin found in muricid mollusc extracts inhibits colon cancer cell proliferation and induces apoptosis, preventing early stage tumor formation in a colorectal cancer rodent model. Marine Drugs, 12(1), 17-35.
    DOI Scopus34 WoS36 Europe PMC23
    2014 Humphreys, K., Conlon, M., Young, G., Topping, D., Hu, Y., Winter, J., . . . Le Leu, R. (2014). Dietary manipulation of oncogenic microRNA expression in human rectal mucosa: a randomized trial. Cancer Prevention Research, 7(8), 786-795.
    DOI Scopus67 WoS66 Europe PMC40
    2013 Martin, J., Young, G., Le Leu, R., & Hu, Y. (2013). Comparing the effects of COX and Non-COX-inhibiting NSAIDs on enhancement of apoptosis and inhibition of aberrant crypt foci formation in a rat colorectal cancer model. Anticancer Research, 33(9), 3581-3588.
    Scopus5 WoS5 Europe PMC4
    2013 Nyskohus, L., Watson, A., Margison, G., Le Leu, R., Kim, S., Lockett, T., . . . Hu, Y. (2013). Repair and removal of azoxymethane-induced O⁶-methylguanine in rat colon by O⁶-methylguanine DNA methyltransferase and apoptosis. Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 758(1-2), 80-86.
    DOI Scopus18 WoS17 Europe PMC10
    2013 Hu, Y., McIntosh, G., Le Leu, R., Nyskohus, L., Woodman, R., & Young, G. (2013). Combination of selenium and green tea improves the efficacy of chemoprevention in a rat colorectal cancer model by modulating genetic and epigenetic biomarkers. PLoS One, 8(5), e64362-1-e64362-12.
    DOI Scopus43 WoS35 Europe PMC23
    2013 Westley, C. B., Benkendorff, K., McIver, C. M., Le Leu, R. K., & Abbott, C. A. (2013). Gastrointestinal and hepatotoxicity assessment of an anticancer extract from muricid molluscs. Evidence-based Complementary and Alternative Medicine, 2013, 12 pages.
    DOI Scopus11 WoS12 Europe PMC5
    2013 Le Leu, R., Young, G., Hu, Y., Winter, J., & Conlon, M. (2013). Dietary red meat aggravates dextran sulfate sodium-induced colitis in mice whereas resistant starch attenuates inflammation. Digestive Diseases and Sciences, 58(12), 3475-3482.
    DOI Scopus60 WoS50 Europe PMC36
    2013 Humphreys, K. J., Cobiac, L., Le Leu, R. K., Van der Hoek, M. B., & Michael, M. Z. (2013). Histone deacetylase inhibition in colorectal cancer cells reveals competing roles for members of the oncogenic miR-17-92 cluster. Molecular Carcinogenesis, 52(6), 459-474.
    DOI Scopus91 WoS80 Europe PMC59
    2011 Hu, Y., McIntosh, G. H., Le Leu, R. K., Upton, J. M., Oodman, R. J., & Young, G. P. (2011). The influence of selenium-enriched milk proteins and selenium yeast on plasma selenium levels and rectal selenoprotein gene expression in human subjects. British Journal of Nutrition, 106(4), 572-582.
    DOI Scopus21 WoS17 Europe PMC12
    2011 Worthley, D., Whitehall, V., Le Leu, R., Irahara, N., Buttenshaw, R., Mallitt, K., . . . Leggett, B. (2011). DNA methylation in the rectal mucosa is associated with crypt proliferation and fecal short-chain fatty acids. Digestive Diseases and Sciences, 56(2), 387-396.
    DOI Scopus19 WoS17 Europe PMC12
    2011 Winter, J., Nyskohus, L., Young, G., Hu, Y., Conlon, M., Bird, A., . . . Le Leu, R. (2011). Inhibition by resistant starch of red meat-induced promutagenic adducts in mouse colon. Cancer Prevention Research, 4(11), 1920-1928.
    DOI Scopus59 WoS56 Europe PMC31
    2010 Worthley, D., Whitehall, V., Buttenshaw, R., Irahara, N., Greco, S., Ramsnes, I., . . . Leggett, B. (2010). DNA methylation within the normal colorectal mucosa is associated with pathway-specific predisposition to cancer. Oncogene, 29(11), 1653-1662.
    DOI Scopus88 WoS85 Europe PMC65
    2010 Westley, C. B., McIver, C. M., Abbott, C. A., Le Leu, R. K., & Benkendorff, K. (2010). Enhanced acute apoptotic response to azoxymethane-induced DNA damage in the rodent colonic epithelium by Tyrian purple precursors: A potential colorectal cancer chemopreventative. Cancer Biology and Therapy, 9(5), 371-379.
    DOI Scopus28 WoS28 Europe PMC20
    2010 Hu, Y., Le Leu, R. K., Nyskohus, L. S., Winter, J., & Young, G. P. (2010). Combination of selenium and green tea improves the efficacy of chemoprevention of selenium and green tea alone in a rat colon cancer model. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 25, A73-A74.
    2010 Le Leu, R. K., Winter, J., Hu, Y., Nyskohus, L., Conlon, M. A., Bird, A. R., . . . Young, G. P. (2010). High dietary protein and DNA damage in the rodent colon: regulation by resistant starch. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 25, A112-A113.
    2010 Le Leu, R. K., Hu, Y., Brown, I. L., Woodman, R. J., & Young, G. P. (2010). Synbiotic intervention of Bifidobacterium lactis and resistant starch protects against colorectal cancer development in rats. Carcinogenesis, 31(2), 246-251.
    DOI Scopus136 WoS126 Europe PMC76
    2010 Hu, Y., McIntosh, G. H., Le Leu, R. K., & Young, G. P. (2010). Selenium-enriched milk proteins and selenium yeast affect selenoprotein activity and expression differently in mouse colon. British Journal of Nutrition, 104(1), 17-23.
    DOI Scopus26 WoS25 Europe PMC14
    2010 Martin, J. E., Le Leu, R. K., Hu, Y., & Young, G. P. (2010). R-flurbiprofen suppresses distal nonmucin-producing colorectal tumors in azoxymethane-treated rats, without suppressing eicosanoid production. American Journal of Physiology - Gastrointestinal and Liver Physiology, 298(6), G860-G864.
    DOI Scopus6 WoS6 Europe PMC4
    2010 Leu, R. K. L., Winter, J. M., Hu, Y., Nyskohus, L. S., Conlon, M., Bird, A. R., . . . Young, G. P. (2010). M1181 Red Meat Diets Increase the Formation of O6-Methyl-2-Deoxyguanosine Adducts in the Mouse Colon: Attenuation by Resistant Starch. Gastroenterology, 138(5), S-349.
    DOI
    2009 Worthley, D. L., Whitehall, V. L., Buttenshaw, R., Mallitt, K. -A., Le Leu, R. K., Young, G. P., & Leggett, B. A. (2009). 199 DNA Methylation Throughout the Normal Human Colorectum: Evidence of An Epigenetic Field Effect. Gastroenterology, 136(5), A-37.
    DOI
    2009 Hu, Y., McIntosh, G. H., Le Leu, R. K., & Young, G. P. (2009). W1958 The Influence of Selenium-Enriched Milk Proteins On Selenium Status and Colorectal Cancer Risk in Humans. Gastroenterology, 136(5), A-761.
    DOI
    2009 Le Leu, R. K., Hu, Y., Brown, I. L., & Young, G. P. (2009). W1964 A Combination of Bifidobacterium Lactis and Resistant Starch Can Protect Against Colorectal Cancer Development in Rats. Gastroenterology, 136(5).
    DOI
    2009 Le Leu, R. K., Hu, Y., Brown, I. L., & Young, G. P. (2009). Effect of high amylose maize starches on colonic fermentation and apoptotic response to DNA-damage in the colon of rats. Nutrition and Metabolism, 6(1), 9 pages.
    DOI Scopus71 WoS67 Europe PMC31
    2009 Worthley, D., Le Leu, R., Whitehall, V., Conlon, M., Christophersen, C., Belobrajdic, D., . . . Young, G. (2009). A human, double-blind, placebo-controlled, crossover trial of prebiotic, probiotic, and synbiotic supplementation: Effects on luminal, inflammatory, epigenetic, and epithelial biomarkers of colorectal cancer. American Journal of Clinical Nutrition, 90(3), 578-586.
    DOI Scopus106 WoS101 Europe PMC59
    2009 Worthley, D. L., Leleu, R., Whitehall, V., Conlon, M., Christophersen, C., Belobrajdic, D., . . . Young, G. (2009). A human, double-blind, placebo-controlled, cross-over trial of prebiotic, probiotic and synbiotic supplementation: effects on luminal, inflammatory, epigenetic and epithelial biomarkers of colorectal cancer. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 24, A239.
    2009 Hu, Y., Le Leu, R. K., & Young, G. P. (2009). Detection of K-ras mutations in azoxymethane-induced aberrant crypt foci in mice using LNA-mediated real-time PCR clamping and mutant-specific probes. Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 677(1-2), 27-32.
    DOI Scopus14 WoS17 Europe PMC7
    2008 Worthley, D. L., Whitehall, V. L., Leleu, R., Buttenshaw, R., Young, G. P., & Leggett, B. A. (2008). DNA methylation throughout the human colorectum is associated with age, region and pathology. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 23, A206.
    2008 Hu, Y., Le Leu, R. K., Belobrajdic, D., & Young, G. P. (2008). The potential of sphingomyelin as a chemopreventive agent in AOM-induced colon cancer model: Wild-type and p53<sup>+/-</sup> mice. Molecular Nutrition and Food Research, 52(5), 558-566.
    DOI Scopus12 WoS11 Europe PMC10
    2008 Hu, Y., McIntosh, G. H., Le Leu, R. K., Woodman, R., & Young, G. P. (2008). Suppression of colorectal oncogenesis by selenium-enriched milk proteins: Apoptosis and K-ras mutations. Cancer Research, 68(12), 4936-4944.
    DOI Scopus51 WoS42 Europe PMC28
    2008 Hu, Y., McIntosh, G. H., Le Leu, R. K., & Young, G. P. (2008). W1105 Suppression of Colon Cancer By Selenium-Enriched Milk Proteins: Enhanced Apoptotic Response to Carcinogen Is Associated with Reduction in Frequency of K-RAS Mutations. Gastroenterology, 134(4), A-634.
    DOI
    2007 Nutrition (2007). Journal of Gastroenterology and Hepatology, 22(s3), A403-A412.
    DOI
    2007 Hu, Y., Le Leu, R. K., & Young, G. P. (2007). Defective acute apoptotic response to genotoxic carcinogen in small intestine of APC<sup>Min/+</sup> mice is restored by sulindac. Cancer Letters, 248(2), 234-244.
    DOI Scopus8 WoS8 Europe PMC4
    2007 Le Leu, R. K., & Young, G. P. (2007). Fermentation of starch and protein in the colon: Implications for genomic instability. Cancer Biology and Therapy, 6(2), 259-260.
    DOI Scopus14 WoS13 Europe PMC7
    2007 Le Leu, R. K., Brown, I. L., Hu, Y., Morita, T., Esterman, A., & Young, G. P. (2007). Effect of dietary resistant starch and protein on colonic fermentation and intestinal tumourigenesis in rats. Carcinogenesis, 28(2), 240-245.
    DOI Scopus106 WoS90 Europe PMC50
    2007 Le Leu, R. K., Brown, I. L., Hu, Y., Esterman, A., & Young, G. P. (2007). Suppression of azoxymethane-induced colon cancer development in rats by dietary resistant starch. Cancer Biology and Therapy, 6(10), 1621-1626.
    DOI Scopus48 WoS47 Europe PMC29
    2007 Benassi-Evans, B., Le Leu, R., Bird, A., Clifton, P., & Fenech, M. (2007). Cytokinesis-block micronucleus cytome assays for the determination of genotoxicity and cytotoxicity of cecal water in rats and fecal water in humans. Cancer Epidemiology Biomarkers & Prevention, 16(12), 2676-2680.
    DOI Scopus13 WoS10 Europe PMC5
    2005 Young, G. P., Hu, Y., Le Leu, R. K., & Nyskohus, L. (2005). Dietary fibre and colorectal cancer: A model for environment - Gene interactions. Molecular Nutrition and Food Research, 49(6), 571-584.
    DOI Scopus120 WoS113 Europe PMC74
    2005 Hu, Y., Le Leu, R. K., & Young, G. P. (2005). Sulindac corrects defective apoptosis and suppresses azoxymethane-induced colonic oncogenesis in p53 knockout mice. International Journal of Cancer, 116(6), 870-875.
    DOI Scopus17 WoS18 Europe PMC13
    2005 Le Leu, R. K., Brown, I. L., Hu, Y., Bird, A. R., Jackson, M., Esterman, A., & Young, G. P. (2005). A synbiotic combination of resistant starch and Bifidobacterium lactis facilitates apoptotic deletion of carcinogen-damaged dells in rat colon. Journal of Nutrition, 135(5), 996-1001.
    DOI Scopus167 WoS144 Europe PMC66
    2005 Hu, Y., Le Leu, R. K., & Young, G. P. (2005). Absence of acute apoptotic response to genotoxic carcinogens in p53-deficient mice is associated with increased susceptibility to azoxymethane-induced colon tumours. International Journal of Cancer, 115(4), 561-567.
    DOI Scopus31 WoS30 Europe PMC24
    2004 Young, G. P., & Le Leu, R. K. (2004). Resistant starch and colorectal neoplasia. Journal of AOAC International, 87(3), 775-786.
    DOI Scopus36 WoS28 Europe PMC14
    2003 Le Leu, R. K., Brown, I. L., Hu, Y., & Young, G. P. (2003). Effect of resistant starch on genotoxin-induced apoptosis, colonic epithelium, and lumenal contents in rats. Carcinogenesis, 24(8), 1347-1352.
    DOI Scopus80 WoS72 Europe PMC41
    2002 Le Leu, R. K., Hu, Y., & Young, G. P. (2002). Effects of resistant starch and nonstarch polysaccharides on colonic luminal environment and genotoxin-induced apoptosis in the rat. Carcinogenesis, 23(5), 713-719.
    DOI Scopus64 WoS59 Europe PMC38
    2002 Hu, Y., Martin, J., Le Leu, R., & Young, G. P. (2002). The colonic response to genotoxic carcinogens in the rat: Regulation by dietary fibre. Carcinogenesis, 23(7), 1131-1137.
    DOI Scopus47 WoS48 Europe PMC28
    2002 Young, G. P., & Le Leu, R. K. (2002). Preventing cancer: dietary lifestyle or clinical intervention?. Asia Pacific journal of clinical nutrition, 11 Suppl 3, S618-S631.
    DOI Scopus23 WoS17 Europe PMC6
    2001 McIntosh, G. H., & Le Leu, R. K. (2001). The influence of dietary proteins on colon cancer risk. Nutrition Research, 21(7), 1053-1066.
    DOI Scopus42 WoS37 Europe PMC16
    2001 Martin, J. E., Young, G. P., James, R., Hu, Y., & Leu, R. L. (2001). Lack of interaction of sulindac and n-3 fatty acids in their effects on colo-rectal tumourigenesis. Gastroenterology, 120(5), A253.
    DOI
    2000 Le Leu, R. K., Young, G. P., & McIntosh, G. H. (2000). Folate deficiency reduces the development of colorectal cancer in rats. Carcinogenesis, 21(12), 2261-2265.
    DOI Scopus72 WoS65 Europe PMC45
    2000 Le Leu, R. K., Young, G. P., & McIntosh, G. H. (2000). Folate deficiency diminishes the occurrence of aberrant crypt foci in the rat colon but does not alter global DNA methylation status. Journal of Gastroenterology and Hepatology (Australia), 15(10), 1158-1164.
    DOI Scopus38 WoS34 Europe PMC23
    1998 Le Leu, R. K., McIntosh, G. H., & Young, G. P. (1998). Ability of endogenous folate from soy protein isolate to maintain plasma homocysteine and hepatic DNA methylation during methyl group depletion in rats. Journal of Nutritional Science and Vitaminology, 44(3), 457-464.
    DOI Scopus9 WoS8 Europe PMC4
    1996 Mcintosh, G. H., Le Leu, R. K., Royle, P. J., & Young, G. P. (1996). A comparative study of the influence of differing barley brans on DMH-induced intestinal tumours in male Sprague-Dawley rats. Journal of Gastroenterology and Hepatology (Australia), 11(2), 113-119.
    DOI Scopus44 WoS36 Europe PMC21
    1996 Noakes, M., Clifton, P. M., Nestel, P. J., Le Leu, R., & McIntosh, G. (1996). Effect of high-amylose starch and oat bran on metabolic variables and bowel function in subjects with hypertriglyceridemia. American Journal of Clinical Nutrition, 64(6), 944-951.
    DOI Scopus149 WoS137 Europe PMC81
    1995 McIntosh, G. H., Regester, G. O., Le Leu, R. K., Royle, P. J., & Smithers, G. W. (1995). Dairy proteins protect against dimethylhydrazine-induced intestinal cancers in rats. Journal of Nutrition, 125(4), 809-816.
    DOI Scopus182 WoS164 Europe PMC73
    1993 MCINTOSH, G. H., LELEU, R. K., KERRY, A., & GOLDRING, M. (1993). BARLEY-GRAIN FOR HUMAN FOOD USE. FOOD AUSTRALIA, 45(8), 392-394.
    WoS6
    1991 Hayball, P. J., Nation, R. L., Bochner, F., & Le Leu, R. K. (1991). Enantiospecific analysis of ketoprofen in plasma by high-performance liquid chromatography. Journal of Chromatography B: Biomedical Sciences and Applications, 570(2), 446-452.
    DOI Scopus26 WoS26 Europe PMC11
  • Conference Papers

    Year Citation
    2012 Roediger, W., Le Leu, R., & Jones, T. (2012). DIVERSION COLITIS TREATMENT WITH RAPIDLY FERMENTABLE FIBRE-SUPPOSITORIES. In GUT Vol. 61 (pp. A93). B M J PUBLISHING GROUP.
    DOI
    2011 Le Leu, R., Winter, J., Hu, Y., Nyskohus, L., Conlon, M., Bird, A., . . . Young, G. (2011). Inhibition by Resistant Starch of Red Meat-Induced Promutagenic Adducts in Mouse Colon.. In ENVIRONMENTAL AND MOLECULAR MUTAGENESIS Vol. 52 (pp. S71). Montreal, CANADA: WILEY-BLACKWELL.
    2011 Hu, Y., Le Leu, R. K., Nyskohus, L. S., Winter, J., & Young, G. P. (2011). Combination of Selenium and Green Tea Improves the Efficacy of Chemoprevention of Selenium and Green Tea Alone in a Rat Colon Cancer Model.. In ENVIRONMENTAL AND MOLECULAR MUTAGENESIS Vol. 52 (pp. S71). Montreal, CANADA: WILEY-BLACKWELL.
    2010 Le Leu, R. K., Winter, J. M., Hu, Y., Nyskohus, L. S., Conlon, M., Bird, A. R., . . . Young, G. P. (2010). Red Meat Diets Increase the Formation of O6-Methyl-2-Deoxyguanosine Adducts in the Mouse Colon: Attenuation by Resistant Starch. In GASTROENTEROLOGY Vol. 138 (pp. S349). W B SAUNDERS CO-ELSEVIER INC.
    2009 Hu, Y., McIntosh, G. H., Le Leu, R. K., & Young, G. P. (2009). The Influence of Selenium-Enriched Milk Proteins On Selenium Status and Colorectal Cancer Risk in Humans. In GASTROENTEROLOGY Vol. 136 (pp. A761). Chicago, IL: W B SAUNDERS CO-ELSEVIER INC.
    2009 Le Leu, R. K., Hu, Y., Brown, I. L., & Young, G. P. (2009). A Combination of Bifidobacterium Lactis and Resistant Starch Can Protect Against Colorectal Cancer Development in Rats. In GASTROENTEROLOGY Vol. 136 (pp. A762-A763). Chicago, IL: W B SAUNDERS CO-ELSEVIER INC.
    WoS1
    2009 Worthley, D. L., Whitehall, V. L., Buttenshaw, R., Mallitt, K. -A., Le Leu, R. K., Young, G. P., & Leggett, B. A. (2009). DNA Methylation Throughout the Normal Human Colorectum: Evidence of An Epigenetic Field Effect. In GASTROENTEROLOGY Vol. 136 (pp. A37). W B SAUNDERS CO-ELSEVIER INC.
    WoS1
    2008 Le Leu, R. K., Hu, Y., Brown, I. L., & Young, G. P. (2008). Synbiotic combination of bifidobacterium lactis and resistant starch can protect against colorectal cancer development. In JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Vol. 23 (pp. A209). WILEY-BLACKWELL PUBLISHING, INC.
    2008 Hu, Y., Mclntosh, G. H., Le Leu, R. K., & Young, G. P. (2008). Suppression of colon cancer by selenium-enriched milk proteins: Enhanced apoptotic response to carcinogen is associated with reduction in frequency of K-RAS mutations. In GASTROENTEROLOGY Vol. 134 (pp. A634). W B SAUNDERS CO-ELSEVIER INC.
    2007 Hu, Y., Leleu, R., Mcintosh, G., & Young, G. (2007). Chemopreventive effect of high selenium enriched milk protein on azoxymethanc-fiaduced colonic tumorigenesis. In GASTROENTEROLOGY Vol. 132 (pp. A439). Washington, DC: W B SAUNDERS CO-ELSEVIER INC.
    2006 Le Leu, R. K., Brown, I. L., Hu, Y., & Young, G. P. (2006). Effect of undigested starch and protein on intestinal tumorigenesis. In JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Vol. 21 (pp. A346). BLACKWELL PUBLISHING.
    2006 Hu, Y., Le Leu, R. K., & Young, G. P. (2006). Detection of K-ras mutation in AOM-induced colonic tumorigenesis by locked nucleic acid (LNA)-mediated PCR clamping and melting curve analysis. In JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Vol. 21 (pp. A268). BLACKWELL PUBLISHING.
    2004 Hu, Y., Le Leu, R. K., & Young, G. P. (2004). Effect of sulindac on acute apoptotic response to carcinogen in p53 knockout mice. In GASTROENTEROLOGY Vol. 126 (pp. A303). New Orleans, LA: W B SAUNDERS CO.
    2003 Martin, J., Leu, L., Hu, Y., & Young, G. (2003). Prevention of colorectal carcinoma in azoxymethane treated rats by non-steroidal anti-inflammatory drugs (NSAIDs) is dependent on histologic type. In GASTROENTEROLOGY Vol. 124 (pp. A604). ORLANDO, FLORIDA: W B SAUNDERS CO.
    DOI
    2002 Hu, Y., Le Leu, R. K., Martin, J. E., & Young, G. (2002). The acute apoptotic response in the colon to DNA damage by carcinogen is dependent on p53 but not APC. In GASTROENTEROLOGY Vol. 122 (pp. A684). W B SAUNDERS CO.
    2001 Martin, J. E., Young, G. P., James, R., Hu, Y., & Le Leu, R. (2001). Lack of interaction of sulindac and n-3 fatty acids in their effects on colo-rectal tumourigenesis. In GASTROENTEROLOGY Vol. 120 (pp. A253). W B SAUNDERS CO.
    DOI
    2001 Le Leu, R. K., Hu, Y., & Young, G. P. (2001). Effects of resistant starch and nonstarch polysaccharides on luminal environment and AOM-induced apoptosis. In GASTROENTEROLOGY Vol. 120 (pp. A667). W B SAUNDERS CO.
    DOI
    1999 Le Leu, R. K., McIntosh, G. H., & Young, G. P. (1999). Effect of folate deficiency on formation of azoxy-methane-induced aberrant crypt foci in the rat colon. In GASTROENTEROLOGY Vol. 116 (pp. A449). W B SAUNDERS CO-ELSEVIER INC.
    WoS1
    1998 McIntosh, G. H., Royle, P. J., Le Leu, R. K., Regester, G. O., Johnson, M. A., Grinsted, R. L., . . . Smithers, G. W. (1998). Whey proteins as functional food ingredients?. In International Dairy Journal Vol. 8 (pp. 425-434). CORK, IRELAND: ELSEVIER SCI LTD.
    DOI Scopus146 WoS126 Europe PMC34
    1996 Noakes, M., Clifton, P. M., Nestel, P. J., LeLeu, R., & McIntosh, G. (1996). Effect of high amylose starch and oat bran on metabolic variables and bowel function in subjects with hypertriglyceridemia. In J. C. B. Miller (Ed.), PROCEEDINGS OF THE NUTRITION SOCIETY OF AUSTRALIA, VOL 20 Vol. 20 (pp. 192). SYDNEY, AUSTRALIA: NUTRITION SOC AUSTRALIA.
  • Conference Items

    Year Citation
    2019 Shannahan, L., Le Leu, R., Bennett, P., Chur-Hansen, A., Burke, A. L., Collins, K., . . . Jesudason, S. (2019). Patient Reported Outcome Measures Over the First Three Months of Dialysis: Interim Results from the Multidisciplinary Assessment at Dialysis Entry (MADE) Study. Poster session presented at the meeting of ISN World Congress of Nephrology. Melbourne, Victoria.
    2012 Winter, J., Nyskohus, L., Young, G. P., Hu, Y., Conlon, M., Bird, A., . . . LeLeu, R. (2012). High Red Meat-Induced Promutagenic Adducts in the Mouse and Human Colon and Their Inhibition by Resistant Starch. Poster session presented at the meeting of ENVIRONMENTAL AND MOLECULAR MUTAGENESIS. Bellevue, WA: WILEY-BLACKWELL.
    2012 Le Leu, R., Conlon, M., Winter, J., Humphreys, K., Michael, M., Hu, Y., . . . Young, G. (2012). Effect of high red meat intake and resistant starch in humans on risk factors for colorectal cancer. Poster session presented at the meeting of Journal of Gastroenterology and Hepatology. Adelaide, SA: Wiley.
    DOI WoS2
    2012 Proctor, S. J., Roediger, W., & Cummins, A. G. (2012). Regional characteristics and proposed mechanisms of mucosal adaptation in short bowel syndrome. Poster session presented at the meeting of Journal of Gastroenterology and Hepatology. Adelaide, SA: Wiley.
    DOI
    2012 Abimosleh, S. M., Cuong, T., Lotfollahi, Z., Penascoza, E. M., Stomaci, D. G., & Howarth, G. (2012). Emu oil maintains intestinal goblet cell numbers and reduces acute inflammation in a rat model of chemotherapy-induced mucositis. Poster session presented at the meeting of Journal of Gastroenterology and Hepatology. Adelaide, SA: Wiley.
    DOI

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