Adelaide Medical School
Faculty of Health and Medical Sciences
I have worked in the Biomedical Orthopaedic Research Lab for 7 years and have recently completed my Doctor of Philosophy in Research. My work focuses on the role of osteocytes in aseptic loosening of total hip replacements. Our lab is very interested in osteocytes, the major cell type in the bone, and the role these cells play in bone homeostasis, disease and aging. We focus on diseases including osteoarthritis and osteoporosis, in an effort to find better molecular targets for drug therapies.
My current research focuses on the role of the osteocyte in total hip replacements (THR). THR is one of the most successful techniques used to improve mobility and alleviate pain in patients with osteoarthritis. Osteocytes are connected throughout the bone and their processes are disrupted when prostheses are surgically implanted. This change to bone structure is of import and could explain why failure of implants occur, which is my current research focus. Osteocytes are key cells and research into these cells may provide insights into how the bone changes with disease state and with aging.
Date Position Institution name 2015 Student University of Adelaide 2011 Research Assistant University of Adelaide
Date Institution name Country Title 2015 - 2019 University of Adelaide Australia Doctor of Philosophy in Research 2003 - 2008 Flinders University Australia Bachelor of Science
Year Citation 2014 Ormsby, R., Findlay, D., Kogawa, M., Anderson, P., Morris, H., & Atkins, G. (2014). Analysis of vitamin D metabolism gene expression in human bone: evidence for autocrine control of bone remodelling. In D. Bikle, A. Norman, & J. Welsh (Eds.), The Journal of Steroid Biochemistry and Molecular Biology Vol. 144 (pp. 110-113). San Francisco, CA, USA: Elsevier.
DOI Scopus18 WoS14 Europe PMC7
2011 Khalid, K., Ormsby, R., Welldon, K., Lim, H., Syazwani, S., FatinNabilah, S., . . . Findlay, D. (2011). RESPONSE TO LOADING IN EX VIVO BOVINE BONE. In OSTEOPOROSIS INTERNATIONAL Vol. 22 (pp. S570). Gold Coast, AUSTRALIA: SPRINGER LONDON LTD. 2011 Ito, N., Kogawa, M., Wijenayaka, A., Welldon, K., Khalid, K., Ormsby, R., . . . Findlay, D. (2011). PHOSPHATE 'SENSING' BY HUMAN BONE. In OSTEOPOROSIS INTERNATIONAL Vol. 22 (pp. S585). Gold Coast, AUSTRALIA: SPRINGER LONDON LTD.
Year Citation 2014 Ito, N., Wijenayaka, A., Prideaux, M., Kogawa, M., Ormsby, R., Bonewald, L., . . . Atkins, G. (2014). Induction of FGF23 expression in IDG-SW3 osteocytes by inflammatory stimuli.. Poster session presented at the meeting of JOURNAL OF BONE AND MINERAL RESEARCH. Houston, TX: WILEY-BLACKWELL.
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