Rebecca Harper

Rebecca Harper
Adelaide Medical School
Faculty of Health and Medical Sciences

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Rebecca Harper

Appointments

Date Position Institution name
2017 Adjunct Lecturer The University of Adelaide
2016 Post-doctoral Research Scientist Royal Adelaide Hospital

Awards and Achievements

Date Type Title Institution Name Amount
2017 Award Best Poster Presentation University of Vermont
2017 Award PhD Thesis Excellence Award Centre for Cancer Biology, University of South Austrlia
2017 Research Award Doctoral Research Medal University of Adelaide
2016 Research Award Dean’s Commendation for Doctoral Thesis Excellence University of Adelaide
2015 Award South Australia/ NT Branch Young Investigator of the Year
2015 Award Asia Pacific Society of Respirology Young Investigator Award
2015 Scholarship American Thoracic Society Abstract Scholarship
2015 Award Ann Woolcock Young Investigator of the Year Thoracic Society of Australia and New Zealand
2013 Scholarship Dawes Top-Up Scholarship 2013 Royal Adelaide Hospital
2012 Scholarship Australian Postgraduate Award
2012 Scholarship Australian Postgraduate Award
2012 Scholarship Lions Medical Research Foundation Top-up Scholarship
2011 Achievement Highest Honours Grade, School of Medicine
2011 Award Scicchitano Award

Education

Date Institution name Country Title
The Australian National University Australia Bachelor of Arts/ Bachelor of Science
University of Adelaide Australia Doctor or Philosophy
University of Adelaide Australia Honours Degree of Bachelor of Health Sciences

Journals

Year Citation
2016 Harper, R., Reynolds, A., Bonder, C. & Reynolds, P. (2016). BMPR2 gene therapy for PAH acts via Smad and non-Smad signalling. Respirology, 21, 4, 727-733.
10.1111/resp.12729
2016 Feng, F., Harper, R. & Reynolds, P. (2016). BMPR2 gene delivery reduces mutation-related PAH and counteracts TGF-β-mediated pulmonary cell signalling. Respirology, 21, 3, 526-532.
10.1111/resp.12712

Conference Papers

Year Citation
2016 Harper, R. L., Ward, R., Bonder, C. S. & Reynolds, P. N. (2016). Smad signalling profiles are altered following BMPR2 augmented EPC delivery in a rat Monocrotaline induced PAH model. Thoracic Society of Australia and New Zealand Annual Scientific Meeting. Perth, WA.
2016 Harper, R. L., Bonder, C. S. & Reynolds, P. N. (2016). BMPR2 Augmented EPC Delivery in a Rat Monocrotaline Induced PAH Model Alters Smad Signalling Profiles. American Thoracic Society Annual Scientific Meeting. San Francisco.
2015 Harper, R. L., Bonder, C. S. & Reynolds, P. N. (2015). Up-regulation of BMPR2 in Rat Derived Endothelial Progenitor Cells Leads to the Attenuation of PAH in a MCT Rat Model. American Thoracic Society Annual Scientific Meeting. Denver, CO, US.
2015 Harper, R. L. & Reynolds, P. N. (2015). BMPR2 Replacement Therapy via In Situ Gene Delivery or Engineered Endothelial Cells Alleviates PAH in a Rat Model. American Society of Gene and Cell Therapy Annual Scientific Meeting. New Orleans, LO, US.
2015 Harper, R. L., Ward, R., Bonder, C. S. & Reynolds, P. N. (2015). Smad and Non Smad Signalling in PAH Following BMPR2 Gene Delivery. American Thoracic Society Annual Scientific Meeting. Denver, CO, US.
2014 Harper, R. L., Bonder, C. S. & Reynolds, P. N. (2014). Isolation and Characterisation of a Defined Populations of Endothelial Progenitor Cells from the Left Ventricle: A Pilot Study. Thoracic Society of Australia and New Zealand Annual Scientific Meeting. Adelaide, SA.
2014 Harper, R. L. & Reynolds, P. N. (2014). BMPR2 upregulation via in situ gene delivery or via engineered endothelial progenitor cells alleviates pulmonary arterial hypertension (PAH) in a rat model. Thoracic Society of Australia and New Zealand Annual Scientific Meeting. Gold Coast, QLD.
2012 Harper, R. L., Reynolds, A. M. & Reynolds, P. N. (2012). Changes in Smad Signalling Leads To Amelioration of PAH Following Gene Delivery of Bone Morphogenetic Protein Receptor Type 2. American Thoracic Society Annual Scientific Meeting. San Francisco, CA, US.
2012 Harper, R., Reynolds, A. & Reynolds, P. (2012). BMPR2 Gene Delivery Shifts Intracellular Smad Activation Profile,“. European Respiratory Society Annual Congress. Vienna, Austria.

Conference Items

Year Citation
2017 Harper, R., Bonder, C. & Reynolds, P. (2017). Vascular remodelling is reversed following BMPR2 modified endothelial progenitor cell therapy in a MCT-induced PAH rat model. 2017 Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ) Annual Scientific Meeting. Canberra, ACT.
2017 Harper, R., Cockshell, M., Bonder, C. & Reynolds, P. (2017). Isolation of exosomes and analysis of their surface markers from PAH peripheral blood derived Endothelial Progenitor Cells. Australasia Extracellular Vesicle Conference. Lorne, Victoria.
2016 Harper, R., Ward, R., Bonder, C. & Reynolds, P. (2016). Vascular remodelling is reversed following BMPR2 modified endothelial progenitor cell therapy in a MCT-induced PAH rat model. European Respiratory Society International Congress 2016 (ERS 2016). London, UK.
10.1183/13993003.congress-2016.PA5088
2014 Harper, R. & Reynolds, P. (2014). Impact of BMPR2 therapy on downstream cell signalling in a PAH model: a microarray study. Thoracic Society of Australia and New Zealand Annual Scientific Meeting. Adelaide, SA.
10.1111/resp.12262_9
2014 Harper, R. & Reynolds, P. (2014). Identification of novel cellular signalling pathways following gene delivery of bone morphogenetic protein receptor type-2: a microarray study. International Conference of the American Thoracic Society (ATS). San Diego, CA.

Theses

Year Citation
2016 Harper, R. L.; (2016); Gene therapy for Pulmonary Arterial Hypertension with Bone Morphogenetic Protein Receptor Type-2 modulation via engineered endothelial progenitor cells or a targeted Adeno-viral construct: changes in Smad and non-Smad signalling contributed to amelioration of disease;

2016 RAH Near Miss Grant                                                                                                                                  $57,205

2015 RAH Research Committee, Clinical Project Grant                                                                                          $50,000

2012 RAH Research Committee, Clinical Project Grant                                                                                          $15,000

Memberships

Date Role Membership Country
2012 - ongoing Member Golden Key Society

Committee Memberships

Date Role Committee Institution Country
2017 - ongoing Member AHMS Floor Management Committee University of Adelaide
2016 - ongoing Representative Local Organising Committee for the 2018 Thoracic Society of Australia and New Zealand Annual Scientific Meeting
2015 - ongoing Member Wet Laboratory Organising Group University of Adelaide
2015 - ongoing Member AHMS Animal Users Group University of Adelaide
2013 - ongoing Representative Local Organising Committee for 2014 Thoracic Society of Australia and New Zealand Annual Scientific Meeting
Phone
83137466
Campus
North Terrace
Building
Adelaide Health and Medical Sciences Building
Room Number
WS7050.16
Org Unit
Health and Medical Sciences Faculty Office

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