Rainer Haberberger

Professor Rainer Haberberger

Wood Jones Chair of Anatomy

School of Biomedicine

Faculty of Health and Medical Sciences

Eligible to supervise Masters and PhD - email supervisor to discuss availability.

Professor Rainer Viktor Haberberger is the Wood Jones Chair in Anatomy at The University of Adelaide, where he also heads up the Peripheral Pain Laboratory. Previously he was Professor of Anatomy & Histology, Head of the Pain & Pulmonary Neurobiology, and Convenor of the Centre for Neuroscience at Flinders University. He studied Human Biology (Medical Research) at the Philipps-University in Marburg, Germany and has been a Senior Scientist and Lecturer at the Institute for Anatomy and Cell Biology, Justus-Liebig University Giessen, Germany until 2005.

His main areas of research interest are novel signalling mechanisms in pain transducing cells and how to utilize those to create a “pain-measurement device”. He received the Collaborative Research Grant of the International Society for the Study of Pain (IASP) 2006 & 2010, the Decima Strachan and Claire Lilia Wooton Estates “Spinal Cord Research Award” of the Australian Brain Foundation 2008 and the Australian Lung Foundation “Ludwig Engel Grant-in-Aid” for Physiological Research 2011. In 2017 he was chief investigator of an application that received the “John Boyd Craig Research Award”, Australian and New Zealand College of Anaesthetists.

Research Summary

Chronic ongoing pain affects millions of people, and similar to cancer, there are different types of pain. Patients suffer for years because available drugs often don’t work very well because they cannot be targeted to a specific pain type. This is because there is no tool available that allows a quick and easy discrimination between pain types. The Peripheral Pain research group looks at reasons why drugs often don’t work that well for people suffering from chronic ongoing pain, what the characteristics of the pain detecting nerve cells in humans are and how we can better predict and define what type of pain people have.  This is to support diagnosis and to guide better treatment strategies. The laboratory collaborates with groups across Adelaide to align and complement techniques such as multiple labelling immuno-histochemistry, cell culture, RNASeq, and lipidomics.

Projects are available for: Honours / PhD / Masters

1. Development of a “neuron-on-chip” microfluidic device to differentiate between chronic pain types

A major clinical problem in treating chronic pain is that it is intrinsically difficult to measure because it encompasses both psycho-behavioural and physiological components. Consequently, low-cost and objective methods of pain assessment are not available, and clinical diagnosis relies heavily on self-reporting from patients. Approaches are urgently needed that can identify chronic pain states and discriminate between different subtypes. These would enhance the accuracy and efficiency of clinical diagnosis, design of treatment plans, and monitoring of treatment effectiveness, while minimizing harm and adverse effects associated with treatment.

In collaboration with Dr Matusica, Flinders University and Prof Nico Voelcker at Monash University, this research program will use a combination of neurobiology and nano-material science to more accurately and efficiently assess common chronic pain conditions via analysis of serum. This approach is based on two key innovations. We have determined how to drive immortalised sensory neurons into two major classes of nociceptor-like cells with distinct sensory capacities that can discriminate between serum samples collected from animal and human models of chronic pain using transcriptomics and calcium imaging. We aim to further identify and characterise the capacity of immortalised sensory neurons to specifically respond to serum obtained from different animal models of chronic pain.

In this research we will also incorporate these cells into a microfluidic device utilising novel “neuron-on-chip” technology. This with the aim to create a biosensor device optimised for analysis of serum samples using machine learning to discriminate between human chronic pain subtypes. A device capable of producing a reliable empirical measure of a chronic pain subtype, which we propose here, would revolutionise the speed and accuracy of diagnostic outcomes, especially for patients who are not capable of verbal self-reporting.

2. Development of a cell-type specific map of human dorsal root ganglia (DRG)

In the field of pain research there is a discrepancy between promising treatments using laboratory animals and the number of successful treatment strategies in humans. This is in part related to differences between sensory neurons in humans and animals. Data related to presence and function of nociceptors and other cell types in DRG cannot necessarily be translated from animal studies to the human situation. For example, the separation of nociceptors in two major classes of peptidergic and non-peptidergic cells is not possible for human nociceptors. Human nociceptors have a different neurochemical profile and utilize different sodium channels to generate action potentials. In addition, it is unknown what cell types comprise a human DRG. Consequently, the effect of treatments such as DRG stimulation on the different cell types in human DRGs is unknown as it is also not known how the cells that exist in human DRG change in response to ongoing chronic pain. This renders neurosurgical procedures and treatments to trial and error experiments.

In collaboration with SAHMRI and the Adelaide Microscopy facility, this research project aims to identify and describe the cell types present in human DRG, define neurochemical characteristics and changes in response to chronic pain. Here we will focus at the presence of non-neuronal cell types such as macrophages, T- and B-cells and mast cells, and define the vasculature including lymphatics. In addition we will use latest technology to create the first lipidomics map of human DRG.

  • Appointments

    Date Position Institution name
    2021 Wood Jones Chair in Anatomy University of Adelaide
    2014 - 2021 Professor of Anatomy & Histology Flinders University
    2009 - 2014 Associate Professor for Neuroscience in Anatomy & Histology Flinders University
    2005 - 2009 Mary Overton Neuroscience Research Fellow Flinders University
    1996 - 2004 Lecturer Technical College Giessen-Friedberg
    1996 - 1997 Lecturer at the Institute for Anatomy and Cell Biology Justus-Liebig-University
    1995 - 2005 Research Fellow and Senior Lecturer at the Institute for Anatomy and Cell Biology Justus-Liebig-University
    1994 - 1995 Scientist and Lecturer at the Institute for Anatomy and Cell Biology Philipps-University
    1992 - 1996 Lecturer Medi-Learn Company
  • Education

    Date Institution name Country Title
    2000 - 2004 Justus-Liebig-University Germany Professorial Degree
    1995 - 1998 Philipp University of Marburg Germany Research Doctorate (PhD) in Neuroscience
    1988 - 1994 Philipp University of Marburg Germany Diploma Medical Research (Human Biology)
  • Postgraduate Training

    Date Title Institution Country
    2000 - 2003 Postdoctoral Fellowship - Acetylcholine receptors of primary afferent neurons Justus-Liebig-University Germany
  • Journals

    Year Citation
    2021 Tran, H. B., Hamon, R., Jersmann, H., Ween, M. P., Asare, P., Haberberger, R., . . . Hodge, S. J. (2021). AIM2 nuclear exit and inflammasome activation in chronic obstructive pulmonary disease and response to cigarette smoke. Journal of Inflammation (United Kingdom), 18(1), 13 pages.
    DOI Scopus1 WoS1
    2020 Chia, K. L., Teoh, J. H., & Haberberger, R. V. (2020). Neuroanatomical relationship between Jingbi and the brachial plexus. Acupuncture in Medicine, 39(3), 964528420938373.
    2020 Haberberger, R. V., Barry, C., & Matusica, D. (2020). Immortalized Dorsal Root Ganglion Neuron Cell Lines. Frontiers in Cellular Neuroscience, 14, 21 pages.
    DOI Scopus6 WoS5 Europe PMC2
    2020 Dusan, M., Jastrow, C., Alyce, M. M., Yingkai, W., Shashikanth, M., Andelain, E., . . . Rainer, H. V. (2020). Differentiation of the 50B11 dorsal ganglion cells into NGF and GDNF responsive nociceptor subtypes. Molecular Pain, 16, 1744806920970368.
    2019 Barry, C. M., Matusica, D., & Haberberger, R. V. (2019). Emerging Evidence of Macrophage Contribution to Hyperinnervation and Nociceptor Sensitization in Vulvodynia. Frontiers in Molecular Neuroscience, 12, 7 pages.
    DOI Scopus3 WoS3 Europe PMC1
    2019 Haberberger, R. V., Barry, C., Dominguez, N., & Matusica, D. (2019). Human dorsal root ganglia. Frontiers in Cellular Neuroscience, 13, 17 pages.
    DOI Scopus46 WoS47 Europe PMC34
    2019 Jiang, Z. J., Delaney, T. L., Zanin, M. P., Haberberger, R. V., Pitson, S. M., Huang, J., . . . Gong, L. W. (2019). Extracellular and intracellular sphingosine-1-phosphate distinctly regulates exocytosis in chromaffin cells. Journal of Neurochemistry, 149(6), 729-746.
    DOI Scopus4 WoS4 Europe PMC2
    2018 Barry, C. M., Ji, E., Sharma, H., Yap, P., Spencer, N. J., Matusica, D., & Haberberger, R. V. (2018). Peptidergic nerve fibers in the urethra: Morphological and neurochemical characteristics in female mice of reproductive age. Neurourology and Urodynamics, 37(3), 960-970.
    DOI Scopus8 WoS8 Europe PMC2
    2018 Barry, C. M., Huilgol, K. K., & Haberberger, R. V. (2018). New models to study vulvodynia: Hyperinnervation and nociceptor sensitization in the female genital tract. Neural Regeneration Research, 13(12), 2096-2097.
    DOI Scopus3 WoS3 Europe PMC3
    2018 Sharma, H., Ji, E., Yap, P., Vilimas, P., Kyloh, M., Spencer, N. J., . . . Barry, C. M. (2018). Innervation Changes Induced by Inflammation in the Murine Vagina. Neuroscience, 372, 16-26.
    DOI Scopus5 WoS4 Europe PMC3
    2018 Gutbier, B., Schönrock, S. M., Ehrler, C., Haberberger, R., Dietert, K., Gruber, A. D., . . . Witzenrath, M. (2018). Sphingosine Kinase 1 Regulates Inflammation and Contributes to Acute Lung Injury in Pneumococcal Pneumonia via the Sphingosine-1-Phosphate Receptor 2. Critical care medicine, 46(3), e258-e267.
    DOI Scopus9 WoS10 Europe PMC7
    2017 Quarta, S., Camprubí-Robles, M., Schweigreiter, R., Matusica, D., Haberberger, R. V., Proia, R. L., . . . Kress, M. (2017). Sphingosine-1-phosphate and the S1P<inf>3</inf> receptor initiate neuronal retraction via RhoA/ROCK associated with CRMP2 phosphorylation. Frontiers in Molecular Neuroscience, 10, 13 pages.
    DOI Scopus18 WoS18 Europe PMC12
    2017 Barry, C. M., Ji, E., Sharma, H., Beukes, L., Vilimas, P. I., DeGraaf, Y. C., . . . Haberberger, R. V. (2017). Morphological and neurochemical differences in peptidergic nerve fibers of the mouse vagina. Journal of Comparative Neurology, 525(10), 2394-2410.
    DOI Scopus4 WoS3 Europe PMC2
    2017 Chia, K. L., & Haberberger, R. V. (2017). Needling depth at BL52 in 13 cadavers. Acupuncture in Medicine, 35(2), 155-156.
    DOI Scopus2 WoS2 Europe PMC1
    2017 Barnawi, J., Jersmann, H., Haberberger, R., Hodge, S., & Meech, R. (2017). Reduced DNA methylation of sphingosine-1 phosphate receptor 5 in alveolar macrophages in COPD: A potential link to failed efferocytosis. Respirology, 22(2), 315-321.
    DOI Scopus20 WoS23 Europe PMC17
    2017 Rojas-Canales, D., Penko, D., Min, K., Parham, K., Peiris, H., Haberberger, R., . . . Jessup, C. (2017). Local sphingosine kinase 1 activity improves islet transplantation. Diabetes, 66(5), 1301-1311.
    DOI Scopus4 WoS4 Europe PMC2
    2016 Tran, H., Barnawi, J., Ween, M., Hamon, R., Roscioli, E., Hodge, G., . . . Hodge, S. (2016). Cigarette smoke inhibits efferocytosis via deregulation of sphingosine kinase signaling: reversal with exogenous S1P and the S1P analogue FTY720. Journal of Leukocyte Biology, 100(1), 195-202.
    DOI Scopus19 WoS19 Europe PMC15
    2016 Barnawi, J., Tran, H. B., Roscioli, E., Hodge, G., Jersmann, H., Haberberger, R., & Hodge, S. (2016). Pro-phagocytic Effects of Thymoquinone on Cigarette Smoke-exposed Macrophages Occur by Modulation of the Sphingosine-1-phosphate Signalling System. COPD: Journal of Chronic Obstructive Pulmonary Disease, 13(5), 653-661.
    DOI Scopus10 WoS10 Europe PMC8
    2016 Chia, K. L., & Haberberger, R. V. (2016). A study to investigate needle insertion at Shenshu (BL23) to puncture psoas major muscle. Journal of Integrative Medicine, 14(2), 128-133.
    DOI Scopus2 Europe PMC1
    2016 Weth-Malsch, D., Langeslag, M., Beroukas, D., Zangrandi, L., Kastenberger, I., Quarta, S., . . . Kress, M. (2016). Ablation of sphingosine 1-phosphate receptor subtype 3 impairs hippocampal neuron excitability in vitro and spatial working memory in vivo. Frontiers in Cellular Neuroscience, 10(NOV2016), 12 pages.
    DOI Scopus9 WoS9 Europe PMC5
    2015 Beroukas, D., Selhorst, M., M. Pitson, S., Matusica, D., L. Gibbins, I., Kress, M., & V. Haberberger, R. (2015). Sphingosine kinase 1 in murine dorsal root ganglia. AIMS Molecular Science, 2(1), 22-33.
    2015 Kestell, G., Anderson, R., Clarke, J., Haberberger, R., & Gibbins, I. (2015). Primary afferent neurons containing calcitonin gene-related peptide but not substance P in forepaw skin, dorsal root ganglia, and spinal cord of mice. Journal of Comparative Neurology, 523(17), 2555-2569.
    DOI Scopus27 WoS25 Europe PMC19
    2015 Canlas, J., Holt, P., Carroll, A., Rix, S., Ryan, P., Davies, L., . . . Haberberger, R. (2015). Sphingosine kinase 2-deficiency mediated changes in spinal pain processing. Frontiers in Molecular Neuroscience, 8(AUGUST), 1-13.
    DOI Scopus15 WoS15 Europe PMC7
    2015 Barnawi, J., Hai, T., Jersmann, H., Pitson, S., Roscioli, E., Hodge, G., . . . Hodge, S. (2015). Potential link between the Sphingosine-1-Phosphate (S1P) system and defective alveolar macrophage phagocytic function in Chronic Obstructive Pulmonary Disease (COPD). PLoS One, 10(10), e0122771-1-e0122771-21.
    DOI Scopus30 WoS29 Europe PMC22
    2015 Barry, C. M., Kestell, G., Gillan, M., Haberberger, R. V., & Gibbins, I. L. (2015). Sensory nerve fibers containing calcitonin gene-related peptide in gastrocnemius, latissimus dorsi and erector spinae muscles and thoracolumbar fascia in mice. Neuroscience, 291, 106-117.
    DOI Scopus21 WoS21 Europe PMC10
    2013 Camprubí-Robles, M., Mair, N., Andratsch, M., Benetti, C., Beroukas, D., Rukwied, R., . . . Kress, M. (2013). Sphingosine-1-phosphate-induced nociceptor excitation and ongoing pain behavior in mice and humans is largely mediated by S1P3 receptor. Journal of Neuroscience, 33(6), 2582-2592.
    DOI Scopus41 WoS44 Europe PMC29
    2012 Sun, Y., Lim, Y., Li, F., Liu, S., Lu, J. J., Haberberger, R., . . . Zhou, X. F. (2012). ProBDNF collapses neurite outgrowth of primary neurons by activating RhoA. PLoS ONE, 7(4), 12 pages.
    DOI Scopus112 WoS74 Europe PMC79
    2011 Schirmer, S. U., Eckhardt, I., Lau, H., Klein, J., DeGraaf, Y. C., Lips, K. S., . . . Haberberger, R. V. (2011). The cholinergic system in rat testis is of non-neuronal origin. Reproduction, 142(1), 157-166.
    DOI Scopus24 WoS24 Europe PMC15
    2011 Mair, N., Benetti, C., Andratsch, M., Leitner, M. G., Constantin, C. E., Camprubí-Robles, M., . . . Haberberger, R. V. (2011). Genetic evidence for involvement of neuronally expressed s1P<inf>1</inf> receptor in nociceptor sensitization and inflammatory pain. PLoS ONE, 6(2), 12 pages.
    DOI Scopus55 WoS55 Europe PMC38
    2011 Vilimas, P. I., Yuan, S. Y., Haberberger, R. V., & Gibbins, I. L. (2011). Sensory innervation of the external genital tract of female Guinea pigs and mice. Journal of Sexual Medicine, 8(7), 1985-1995.
    DOI Scopus16 WoS16 Europe PMC10
    2011 Park, K., Haberberger, R. V., Gordon, T. P., & Jackson, M. W. (2011). Antibodies interfering with the type 3 muscarinic receptor pathway inhibit gastrointestinal motility and cholinergic neurotransmission in Sjögren's syndrome. Arthritis and Rheumatism, 63(5), 1426-1434.
    DOI Scopus41 WoS41 Europe PMC21
    2011 Cordts, F., Pitson, S., Tabeling, C., Gibbins, I., Moffat, D., Jersmann, H., . . . Haberberger, R. (2011). Expression profile of the sphingosine kinase signalling system in the lung of patients with chronic obstructive pulmonary disease. Life Sciences, 89(21-22), 806-811.
    DOI Scopus26 WoS24 Europe PMC20
    2011 Tam Tam, S., Bastian, I., Zhou, X., Vander Hoek, M., Michael, M., Gibbins, I., & Haberberger, R. (2011). MicroRNA-143 expression in dorsal root ganglion neurons. Cell and Tissue Research, 346(2), 163-173.
    DOI Scopus30 WoS27 Europe PMC24
    2011 Bastian, I., Tam Tam, S., Zhou, X., Kazenwadel, J., Van Der Hoek, M., Michael, M., . . . Haberberger, R. (2011). Differential expression of microRNA-1 in dorsal root ganglion neurons. Histochemistry and Cell Biology, 135(1), 37-45.
    DOI Scopus14 WoS13 Europe PMC13
    2011 Clarke, J. N., Anderson, R. L., Haberberger, R. V., & Gibbins, I. L. (2011). Non-peptidergic small diameter primary afferents expressing VGluT2 project to lamina I of mouse spinal dorsal horn. Molecular Pain, 7, 17 pages.
    DOI Scopus9 WoS9 Europe PMC8
    2010 Wilson, A. J., Carati, C. J., Gannon, B. J., Haberberger, R., & Chataway, T. K. (2010). Aquaporin-1 in blood vessels of rat circumventricular organs. Cell and Tissue Research, 340(1), 159-168.
    DOI Scopus22 WoS20 Europe PMC16
    2009 Jositsch, G., Papadakis, T., Haberberger, R. V., Wolff, M., Wess, J., & Kummer, W. (2009). Suitability of muscarinic acetylcholine receptor antibodies for immunohistochemistry evaluated on tissue sections of receptor gene-deficient mice. Naunyn-Schmiedeberg's Archives of Pharmacology, 379(4), 389-395.
    DOI Scopus117 WoS107 Europe PMC82
    2009 Haberberger, R. V., Tabeling, C., Runciman, S., Gutbier, B., König, P., Andratsch, M., . . . Witzenrath, M. (2009). Role of sphingosine kinase 1 in allergen-induced pulmonary vascular remodeling and hyperresponsiveness. Journal of Allergy and Clinical Immunology, 124(5), 933-941.
    DOI Scopus30 WoS27 Europe PMC15
    2009 Klein, M. K., Haberberger, R. V., Hartmann, P., Faulhammer, P., Lips, K. S., Krain, B., . . . König, P. (2009). Muscarinic receptor subtypes in cilia-driven transport and airway epithelial development. European Respiratory Journal, 33(5), 1113-1121.
    DOI Scopus43 WoS34 Europe PMC23
    2008 Kindt, F., Wiegand, S., Niemeier, V., Kupfer, J., Löser, C., Nilles, M., . . . Haberberger, R. V. (2008). Reduced expression of nicotinic α subunits 3, 7, 9 and 10 in lesional and nonlesional atopic dermatitis skin but enhanced expression of α subunits 3 and 5 in mast cells. British Journal of Dermatology, 159(4), 847-857.
    DOI Scopus32 WoS27 Europe PMC18
    2008 Ahlbrecht, K., Schmitz, J., Seay, U., Schwarz, C., Mittnacht-Kraus, R., Gaumann, A., . . . Voswinckel, R. (2008). Spatiotemporal expression of flk-1 in pulmonary epithelial cells during lung development. American Journal of Respiratory Cell and Molecular Biology, 39(2), 163-170.
    DOI Scopus13 WoS12 Europe PMC10
    2008 Kress, M., Karasek, J., Ferrer-Montiel, A. V., Scherbakov, N., & Haberberger, R. V. (2008). TRPC channels and diacylglycerol dependent calcium signaling in rat sensory neurons. Histochemistry and Cell Biology, 130(4), 655-667.
    DOI Scopus30 WoS30 Europe PMC23
    2007 Kindt, F., Wiegand, S., Löser, C., Nilles, M., Niemeier, V., Hsu, S. Y. T., . . . Haberberger, R. V. (2007). Intermedin: A skin peptide that is downregulated in atopic dermatitis. Journal of Investigative Dermatology, 127(3), 605-613.
    DOI Scopus11 WoS12 Europe PMC7
    2006 Haberberger, R., Schultheiss, G., & Diener, M. (2006). Epithelial muscarinic M<inf>1</inf> receptors contribute to carbachol-induced ion secretion in mouse colon. European Journal of Pharmacology, 530(3), 229-233.
    DOI Scopus30 WoS29 Europe PMC24
    2006 Plato, M., Kummer, W., & Haberberger, R. V. (2006). Structural and neurochemical comparison of vagal and spinal afferent neurons projecting to the rat lung. Neuroscience Letters, 395(3), 215-219.
    DOI Scopus27 WoS26 Europe PMC19
    2006 Kummer, W., Wiegand, S., Akinci, S., Wessler, I., Schinkel, A. H., Wess, J., . . . Lips, K. S. (2006). Role of acetylcholine and polyspecific cation transporters in serotonin-induced bronchoconstriction in the mouse. Respiratory Research, 7(1), 12 pages.
    DOI Scopus63 WoS59 Europe PMC40
    2006 Groth, M., Helbig, T., Grau, V., Kummer, W., & Haberberger, R. V. (2006). Spinal afferent neurons projecting to the rat lung and pleura express acid sensitive channels. Respiratory Research, 7(1), 16 pages.
    DOI Scopus24 WoS18 Europe PMC15
    2005 Chang, C. L., Roh, J., Park, J. I., Klein, C., Cushman, N., Haberberger, R. V., & Hsu, S. Y. T. (2005). Intermedin functions as a pituitary paracrine factor regulating prolactin release. Molecular Endocrinology, 19(11), 2824-2838.
    DOI Scopus34 WoS29 Europe PMC22
    2005 Pfaff, M., Powaga, N., Akinci, S., Schütz, W., Banno, Y., Wiegand, S., . . . Haberberger, R. V. (2005). Activation of the SPHK/S1P signalling pathway is coupled to muscarinic receptor-dependent regulation of peripheral airways. Respiratory Research, 6(1), 14 pages.
    DOI Scopus34 WoS31 Europe PMC29
    2005 Sequeira, I. M., Haberberger, R. V., & Kummer, W. (2005). Atrial and ventricular rat coronary arteries are differently supplied by noradrenergic, cholinergic and nitrergic, but not sensory nerve fibres. Annals of Anatomy, 187(4), 345-355.
    DOI Scopus16 WoS13 Europe PMC9
    2005 Lang, P. M., Burgstahler, R., Haberberger, R. V., Sippel, W., & Grafe, P. (2005). A conus peptide blocks nicotinic receptors of unmyelinated axons in human nerves. NeuroReport, 16(5), 479-483.
    DOI Scopus26 WoS26 Europe PMC18
    2004 Papadopolou, S., Hartmann, P., Lips, K. S., Kummer, W., & Haberberger, R. V. (2004). Nicotinic receptor mediated stimulation of NO-generation in neurons of rat thoracic dorsal root ganglia. Neuroscience Letters, 361(1-3), 32-35.
    DOI Scopus19 WoS19 Europe PMC14
    2004 Henrich, M., Paddenberg, R., Haberberger, R. V., Scholz, A., Gruss, M., Hempelmann, G., & Kummer, W. (2004). Hypoxic increase in nitric oxide generation of rat sensory neurons requires activation of mitochondrial complex II and voltage-gated calcium channels. Neuroscience, 128(2), 337-345.
    DOI Scopus13 WoS11 Europe PMC11
    2004 Haberberger, R. V., Bernardini, N., Kress, M., Hartmann, P., Lips, K. S., & Kummer, W. (2004). Nicotinic acetylcholine receptor subtypes in nociceptive dorsal root ganglion neurons of the adult rat. Autonomic Neuroscience: Basic and Clinical, 113(1-2), 32-42.
    DOI Scopus63 WoS66 Europe PMC44
    2003 Pfeil, U., Lips, K. S., Eberling, L., Grau, V., Haberberger, R. V., & Kummer, W. (2003). Expression of the high-affinity choline transporter, CHT1, in the rat trachea. American Journal of Respiratory Cell and Molecular Biology, 28(4), 473-477.
    DOI Scopus43 WoS41 Europe PMC35
    2003 Lips, K. S., Pfeil, U., Reiners, K., Rimasch, C., Kuchelmeister, K., Braun-Dullaeus, R. C., . . . Kummer, W. (2003). Expression of the High-affinity Choline Transporter CHT1 in Rat and Human Arteries. Journal of Histochemistry and Cytochemistry, 51(12), 1645-1654.
    DOI Scopus39 WoS38 Europe PMC32
    2003 Hagner, S., Haberberger, R., Hay, D. L., Facer, P., Reiners, K., Voigt, K., & McGregor, G. P. (2003). Immunohistochemical detection of the calcitonin receptor-like receptor protein in the microvasculature of rat endothelium. European Journal of Pharmacology, 481(2-3), 147-151.
    DOI Scopus12 WoS12 Europe PMC9
    2003 Dvorakova, M., Haberberger, R. V., Hagner, S., McGregor, G. P., Slavikova, J., & Kummer, W. (2003). Expression and distribution of the calcitonin receptor-like receptor in the developing rat heart. Anatomy and Embryology, 207(4-5), 307-315.
    DOI Scopus7 WoS7 Europe PMC7
    2003 Henrich, M., Haberberger, R. V., Hempelmann, G., & Kummer, W. (2003). Quantitative immunohistochemical investigation of the intrinsic vasodilator innervation of the guinea pig lingual artery. Autonomic Neuroscience: Basic and Clinical, 103(1-2), 72-82.
    DOI Scopus7 WoS7 Europe PMC6
    2003 Voswinckel, R., Ziegelhoeffer, T., Heil, M., Kostin, S., Breier, G., Mehling, T., . . . Seeger, W. (2003). Circulating vascular progenitor cells do not contribute to compensatory lung growth. Circulation Research, 93(4), 372-379.
    DOI Scopus77 WoS73 Europe PMC49
    2003 Struckmann, N., Schwering, S., Wiegand, S., Gschnell, A., Yamada, M., Kummer, W., . . . Haberberger, R. V. (2003). Role of Muscarinic Receptor Subtypes in the Constriction of Peripheral Airways: Studies on Receptor-Deficient Mice. Molecular Pharmacology, 64(6), 1444-1451.
    DOI Scopus89 WoS78 Europe PMC74
    2003 Haberberger, R. V., Henrich, M., Lips, K. S., & Kummer, W. (2003). Nicotinic receptor alpha7-subunits are coupled to the stimulation of nitric oxide synthase in rat dorsal root ganglion neurons. Histochemistry and Cell Biology, 120(3), 173-181.
    DOI Scopus29 WoS28 Europe PMC21
    2002 Hagner, S., Knauer, J., Haberberger, R., Göke, B., Voigt, K., & McGregor, G. P. (2002). Calcitonin receptor-like receptor is expressed on gastrointestinal immune cells. Digestion, 66(4), 197-203.
    DOI Scopus21 WoS16 Europe PMC15
    2002 Brüggmann, D., Lips, K. S., Pfeil, U., Haberberger, R. V., & Kummer, W. (2002). Multiple nicotinic acetylcholine receptora α-subunits are expressed in the arterial system of the rat. Histochemistry and Cell Biology, 118(6), 441-447.
    DOI Scopus38 WoS37 Europe PMC29
    2002 Hagner, S., Haberberger, R. V., Overkamp, D., Hoffmann, R., Voigt, K. H., & McGregor, G. P. (2002). Expression and distribution of calcitonin receptor-like receptor in human hairy skin. Peptides, 23(1), 109-116.
    DOI Scopus36 WoS34 Europe PMC23
    2002 Haberberger, R. V., Pfeil, U., Lips, K. S., & Kummer, W. (2002). Expression of the high-affinity choline transporter, CHT1, in the neuronal and non-neuronal cholinergic system of human and rat skin. Journal of Investigative Dermatology, 119(4), 943-948.
    DOI Scopus39 WoS37 Europe PMC32
    2002 Lips, K. S., Pfeil, U., Haberberger, R. V., & Kummer, W. (2002). Localisation of the high-affinity choline transporter-1 in the rat skeletal motor unit. Cell and Tissue Research, 307(3), 275-280.
    DOI Scopus37 WoS34 Europe PMC26
    2001 Bernardini, N., Sauer, S. K., Haberberger, R., Fischer, M. J. M., & Reeh, P. W. (2001). Excitatory nicotinic and desensitizing muscarinic (M2) effects on C-nociceptors in isolated rat skin. Journal of Neuroscience, 21(9), 3295-3302.
    DOI Scopus79 WoS72 Europe PMC70
    2001 Hagner, S., Haberberger, R., Kummer, W., Springer, J., Fischer, A., Böhm, S., . . . McGregor, G. P. (2001). Immunohistochemical detection of calcitonin gene-related peptide receptor (CGRPR)-1 in the endothelium of human coronary artery and bronchial blood vessels. Neuropeptides, 35(1), 58-64.
    DOI Scopus30 WoS27 Europe PMC18
    2000 Haberberger, R. V., Bodenbenner, M., & Kummer, W. (2000). Expression of the cholinergic gene locus in pulmonary arterial endothelial cells. Histochemistry and Cell Biology, 113(5), 379-387.
    DOI Scopus41 WoS38 Europe PMC24
    2000 Haberberger, R. V., & Bodenbenner, M. (2000). Immunohistochemical localization of muscarinic receptors (M2) in the rat skin. Cell and Tissue Research, 300(3), 389-396.
    DOI Scopus28 WoS23 Europe PMC21
    2000 Haberberger, R., Scholz, A., Kummer, W., & Kress, M. (2000). M2-receptor subtype does not mediate muscarine-induced increases in [Ca<sup>2+</sup>](i) in nociceptive neurons of rat dorsal root ganglia. Journal of Neurophysiology, 84(4), 1934-1941.
    DOI Scopus26 WoS26 Europe PMC20
    2000 Lührmann, A., Haberberger, R. V., Mörike, C., Steinhoff, G., Krug, N., Pabst, R., & Tschernig, T. (2000). The recruitment of immune cells into a grafted lung is not impaired in spite of incomplete reinnervation. Pneumologie, 54(12), 564-568.
    1999 Kummer, W., Shigemoto, R., & Haberberger, R. (1999). Smooth muscle cells are the site of neurokinin-1 receptor localization in the arterial supply of the rat sciatic nerve. Neuroscience Letters, 259(2), 119-122.
    DOI Scopus12 WoS11 Europe PMC11
    1999 Haberberger, R., Henrich, M., Couraud, J. Y., & Kummer, W. (1999). Muscarinic M2-receptors in rat thoracic dorsal root ganglia. Neuroscience Letters, 266(3), 177-180.
    DOI Scopus19 WoS18 Europe PMC11
    1998 Kummer, W., Fink, L., Dvorakova, M., Haberberger, R., & Bohle, R. M. (1998). Rat cardiac neurons express the non-coding R-exon (exon 1) of the cholinergic gene locus. NeuroReport, 9(10), 2209-2212.
    DOI Scopus19 WoS19 Europe PMC16
    1997 Haberberger, R., Schemann, M., Sann, H., & Kummer, W. (1997). Innervation pattern of guinea pig pulmonary vasculature depends on vascular diameter. Journal of Applied Physiology, 82(2), 426-434.
    DOI Scopus35 WoS29 Europe PMC22
    1997 Dötsch, J., Hänze, J., Dittrich, K., Demirakça, S., Haberberger, R., & Rascher, W. (1997). Stimulation of neuropeptide Y release in rat pheochromocytoma cells by nitric oxide. European Journal of Pharmacology, 331(2-3), 313-317.
    DOI Scopus9 WoS9 Europe PMC5
    1996 Haberberger, R., & Kummer, W. (1996). β2-Adrenoreceptor immunoreactivity in cardiac ganglia of the guinea pig. Histochemical Journal, 28(11), 827-833.
    DOI Scopus6 WoS6 Europe PMC3
    DOI WoS23 Europe PMC18
  • Conference Papers

    Year Citation
    2012 Camprubi-Robles, M., Mair, N., Andratsch, M., Benetti, C., Schmelz, M., Beroukas, D., . . . Kress, M. (2012). Sphingosine-1-phosphate evokes excitation of sensory neurons and nociception in mice and humans. In FEBS JOURNAL Vol. 279 (pp. 374). Seville, SPAIN: WILEY-BLACKWELL.
    2012 Gutbier, B., Schoenrock, S. M., Haberberger, R., Hocke, A. C., Hippenstiel, S., Lueth, A., . . . Witzenrath, M. (2012). Sphingosine kinase-1 and sphingosine-1-phosphate promote the development of acute lung injury in pneumoccocal pneumonia. In EUROPEAN RESPIRATORY JOURNAL Vol. 40 (pp. 2 pages). EUROPEAN RESPIRATORY SOC JOURNALS LTD.
    2008 Ahlbrecht, K., Seay, U., Schmitz, J., Haberberger, R. V., Kraus, R. M., Herold, S., . . . Voswinckel, R. (2008). Impact of the epithelial HIF 2 alpha system on lungdevelopment. In FASEB JOURNAL Vol. 22 (pp. 1 page). FEDERATION AMER SOC EXP BIOL.
    2007 Lips, K. S., Lührmann, A., Tschernig, T., Stoeger, T., Alessandrini, F., Grau, V., . . . Kummer, W. (2007). Down-regulation of the non-neuronal acetylcholine synthesis and release machinery in acute allergic airway inflammation of rat and mouse. In Life Sciences Vol. 80 (pp. 2263-2269). Mainz, GERMANY: PERGAMON-ELSEVIER SCIENCE LTD.
    DOI Scopus57 WoS51 Europe PMC34
    2006 Kummer, W., Wiegand, S., Akinci, S., Schinkel, A. H., Wess, J., Koepsell, H., . . . Lips, K. S. (2006). Role of acetylcholine and muscarinic receptors in serotonin-induced bronchoconstriction in the mouse. In Journal of Molecular Neuroscience Vol. 30 (pp. 67-68). Alicante, SPAIN: HUMANA PRESS INC.
    DOI Scopus21 WoS19 Europe PMC15
    2006 Spies, M., Lips, K. S., Kurzen, H., Kummer, W., & Haberberger, R. V. (2006). Nicotinic acetylcholine receptors containing subunits α3 and α5 in rat nociceptive dorsal root ganglion neurons. In Journal of Molecular Neuroscience Vol. 30 (pp. 55-56). Alicante, SPAIN: HUMANA PRESS INC.
    DOI Scopus15 WoS15 Europe PMC10
    2006 Lips, K. S., König, P., Schätzle, K., Pfeil, U., Krasteva, G., Spies, M., . . . Kummer, W. (2006). Coexpression and spatial association of nicotinic acetylcholine receptor subunits α7 and α10 in rat sympathetic neurons. In Journal of Molecular Neuroscience Vol. 30 (pp. 15-16). Alicante, SPAIN: HUMANA PRESS INC.
    DOI Scopus25 WoS25 Europe PMC23
    2003 Brüggmann, D., Lips, K. S., Pfeil, U., Haberberger, R. V., & Kummer, W. (2003). Rat arteries contain multiple nicotinic acetylcholine receptor α-subunits. In Life Sciences Vol. 72 (pp. 2095-2099). SAN FRANCISCO, CALIFORNIA: PERGAMON-ELSEVIER SCIENCE LTD.
    DOI Scopus30 WoS30 Europe PMC25
    2003 Pfeil, U., Haberberger, R. V., Lips, K. S., Eberling, L., Grau, V., & Kummer, W. (2003). Expression of the high-affinity choline transporter CHT1 in epithelia. In Life Sciences Vol. 72 (pp. 2087-2090). SAN FRANCISCO, CALIFORNIA: PERGAMON-ELSEVIER SCIENCE LTD.
    DOI Scopus21 WoS17 Europe PMC15
    2000 Kummer, W., Haberberger, R., & Fischer, A. (2000). Choline acetyltransferase in the airway wall. In European Respiratory Review Vol. 10 (pp. 257-259).
    1999 Kummer, W., & Haberberger, R. (1999). Extrinsic and intrinsic cholinergic systems of the vascular wall. In European Journal of Morphology Vol. 37 (pp. 223-226). LNTEREN, NETHERLANDS: SWETS ZEITLINGER PUBLISHERS.
    DOI Scopus14 WoS15 Europe PMC11

As chair of Anatomy, I aim to oversee Anatomy teaching across the University. My current teaching involves the development and coordination of the Allied Health course "Upper Limb, Head and Neuroscience" for 2nd year Physiotherapy students and the 2nd year Speech Pathology course "Anatomy and Physiology for Speech and Swallowing". In addition, I am responsible for the development and coordination of the "Cardiovascular" and "Respiratory" modules in the Foundation of Medicine part of the Bachelor of Medical Studies and Doctor of Medicine degree. 

  • Past Higher Degree by Research Supervision (University of Adelaide)

    Date Role Research Topic Program Degree Type Student Load Student Name
    2011 - 2015 External Supervisor Genetic and Epigenetic Characterization of the Sphingosine-1-Phosphate Signalling System in Macrophages in Chronic Obstructive Pulmonary Disease Doctor of Philosophy Doctorate Full Time Mr Jameel Barnawi
  • Position: Wood Jones Chair of Anatomy
  • Phone: 83137390
  • Email: rainer.haberberger@adelaide.edu.au
  • Campus: North Terrace
  • Building: Helen Mayo North
  • Room: 217
  • Org Unit: School of Biomedicine

Connect With Me
External Profiles