Prabin Gyawali

Dr Prabin Gyawali

Research Officer

Adelaide Medical School

Faculty of Health and Medical Sciences


Dr Gyawali possess a PhD in Medicine, MSc in Clinical Biochemistry, and a BSc in Medical Laboratory Science equivalent to the educational level of an Australian Qualifications Framework level 10, level 9 and level 8, respectively, as assessed through the Australian Institute of Medical and Clinical Scientists. These qualifications build a firm basis, theoretical and empirical, in fundamental aspects of clinical biochemistry, pathology, and laboratory medicine.

Dr Gyawali is currently a Research Officer in Dr Nicole McPherson's laboratory at the University of Adelaide in the Male Reproductive Life Course group within Freemasons Centre for Male Health & Wellbeing and Robinson Research Institute. In his role, Dr Gyawali needs to support research activities and assist with specific studies – Diet for Dads Sperm (D4Ds) and reactive oxygen species in sperm (ROSS). Their research examines the biology of how disease risk is transferred via sperm and uses this knowledge to develop tests of risk and interventions for use in IVF practice and family planning.

Before moving to Australia to complete his PhD, Dr Gyawali worked for 12 years in both a clinical and academic position at the Kathmandu University School of Medical Sciences, Dhulikhel Hospital, Dhulikhel, Nepal, as a Clinical Biochemist/Scientist in charge and Lecturer of Medical Sciences.

In his clinical role, Dr Gyawali was responsible for the day-to-day operations of the clinical biochemistry section, sub-speciality expertise, overseeing selection/recommendation of scientific instrumentation/automation, scientific assay development and validation, staff training and supervision and implementation and performance evaluation of new testing methods and instrumentation, quality assurance programs, clinical reporting and clinical liaison, clinical interpretation of laboratory test results and consultation, and advisory service.

In his academic role, Dr Gyawali was responsible for teaching undergraduate programs, primarily biochemistry conveyed as a series of sequential system-based blocks that incorporate active learning strategies into large and small group settings, besides service-based teaching in the laboratory's consult service. These included undergraduate students (medicine, dentistry, nursing, human biology, physiotherapy & medical laboratory technology), clinical placement trainees, and interns. Dr Gyawali was demonstrably an excellent teacher, embracing contemporary pedagogical approaches for medical education, including Problem-based learning, Team-based learning, and the Flip classroom model.

Dr Gyawali was also a co-investigator on locally funded research projects in Nepal, which were broad in topic, consistent with his role in a clinical laboratory setting and his interest in the cardio-metabolic disease, endocrinology, error investigation in the total testing process, and total quality management. Dr Gyawali has mentored 12 coursework undergraduate students (biomedical), and Dr Gyawali is incredibly proud of his students who have completed their own highly successful careers. Dr Gyawali has 17 peer-reviewed articles, seven as the first author. Dr Gyawali has presented his research in more than twenty conferences and forums. Dr Gyawali is honoured to be awarded travel grants for his abstracts and recognition for his presentations at National and International Meetings, including two young scientist awards.

During his role, Dr Gyawali has also served the human research ethics & institutional review committee at the Kathmandu University School of Medical Sciences, Dhulikhel Hospital, Dhulikhel, Nepal.

Dr Gyawali's academic involvement led him to undertake a PhD at the University of Adelaide to develop a high level of competence in statistical analysis of longitudinal cohort data and a wide range of technical skills in molecular biology. For his PhD, Dr Gyawali was awarded a full scholarship from the Australian government research training program that is highly competitive and merit-based, which involved analysis of longitudinal cohort data and a basic science laboratory project. Dr Gyawali's PhD thesis is relevant to pathology, has advanced understanding of the role and regulation of sex hormone-binding globulin (SHBG) as a marker of (i) chronic disease risk and (ii) prostate cancer stage and grade. Dr Gyawali received a Dean's commendation for his PhD, which has produced four publications in top tier journals.

Dr Gyawali's research interest lies in optimising appropriate laboratory test utilisation in clinical biochemistry, SHBG and cardiometabolic disease, SHBG and Prostate Cancer, error investigation in the total testing process, ROS in sperms, and biomarker identification in the present circumstances.

Dr Gyawali is an active member of the Australasian Association for Clinical Biochemistry and Laboratory Medicine and the Australian Institute of Medical and Clinical Scientists, corresponding past members of the Analytical Quality Sub-committee of the International Federation of Clinical Chemistry and Laboratory Medicine, a founding member & elected Treasurer, Nepalese Association for Clinical Chemistry and have also served several other organisations.

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  • Journals

    Year Citation
    2019 Gyawali, P., Martin, S. A., Heilbronn, L. K., Vincent, A. D., Jenkins, A. J., Januszewski, A. S., . . . Wittert, G. A. (2019). Higher serum sex hormone-binding globulin levels are associated with incident cardiovascular disease in men. Journal of Clinical Endocrinology and Metabolism, 104(12), 6301-6315.
    DOI Scopus12 WoS12 Europe PMC6
    2018 Gyawali, P., Martin, S., Heilbronn, L., Vincent, A., Taylor, A., Adams, R., . . . Wittert, G. (2018). The role of sex hormone-binding globulin (SHBG), testosterone, and other sex steroids, on the development of type 2 diabetes in a cohort of community-dwelling middle-aged to elderly men. Acta Diabetologica, 55(8), 861-872.
    DOI Scopus17 WoS17 Europe PMC8
    2018 Gyawali, P., Martin, S., Heilbronn, L., Vincent, A., Jenkins, A., Januszewski, A., . . . Wittert, G. (2018). Cross-sectional and longitudinal determinants of serum sex hormone binding globulin (SHBG) in a cohort of community-dwelling men. PLoS ONE, 13(7), e0200078-1-e0200078-15.
    DOI Scopus8 WoS10 Europe PMC4
    2015 Gyawali, P., Takanche, J., Shrestha, R., Bhattarai, P., Khanal, K., Risal, P., & Koju, R. (2015). Pattern of thyroid dysfunction in patients with metabolic syndrome and its relationship with components of metabolic syndrome. Diabetes & Metabolism Journal, 39(1), 66-73.
    DOI Scopus28 WoS25 Europe PMC15
    2015 Acharya, D., Bogati, B., Shrestha, G., & Gyawali, P. (2015). Diabetes mellitus and urinary tract infection: spectrum of uropathogens and their antibiotic sensitivity. Journal of Manmohan Memorial Institute of Health Sciences, 1(4), 1-28.
    DOI
    2014 Karn, D., KC, S., Timalsina, M., & Gyawali, P. (2014). Hormonal profile and efficacy of long pulse Nd-YAG laser in treatment of hirsutism. Journal of Nepal Health Research Council, 12(26), 59-62.
    Scopus7 Europe PMC4
    2014 Acharya, D., Shrestha, A., Bogati, B., Khanal, K., Shrestha, S., & Gyawali, P. (2014). Serological screening of TORCH agents as an etiology of spontaneous abortion in Dhulikhel hospital, Nepal. American Journal of Biomedical and Life Sciences, 2(2), 34-39.
    DOI
    2013 Gurung, R., Purbe, B., Gyawali, P., & Risal, P. (2013). The ratio of aspartate aminotransferase to alanine aminotransferase (AST/ALT): the correlation of value with underlying severity of alcoholic liver disease. Kathmandu University Medical Journal, 11(3), 233-236.
    DOI Scopus18 Europe PMC7
    2013 Nepal, O., Pokharel, B., Khanal, K., Gyawali, P., Malik, S., Koju, R., & Kapoor, B. (2013). Thyroid hormone levels in Highlanders- a comparison between residents of two altitudes in Nepal. Kathmandu University Medical Journal, 11(1), 18-21.
    DOI
    2013 Nepal, O., Pokhrel, B. R., Khanal, K., Gyawali, P., Malik, S. L., Koju, R., & Kapoor, B. K. (2013). Thyroid hormone levels in highlanders-a comparison between residents of two altitudes in Nepal. Kathmandu University Medical Journal, 11(41), 18-21.
    DOI Scopus3
    2012 Gyawali, P., Tamrakar, S., Lamsal, N., & Shresta, R. (2012). Practice of patient based quality assessment procedure in clinical chemistry unit at diagnostic laboratories in Nepal. Sunsari Technical College Journal, 1(1), 9-17.
    DOI
    2011 Mukherjee, M., Gyawali, P., Thakur, R. K., Shenoy, R. P., & Rao, A. (2011). Assessment of frequency of micronucleated exfoliated buccal cells in relation to oxidative stress in oral lichen planus in coastal Karnataka, India. Asian Pacific Journal of Tropical Disease, 1(4), 287-288.
    DOI Scopus5
    2011 Gyawali, P., Lamsal, N., Tamrakar, S., Shrestha, R., Aryal, P., Raut, B., & Aryal, M. (2011). Quality assessment and good laboratory practice in clinical chemistry laboratory at diagnostic laboratories in Nepal. CLINICAL BIOCHEMISTRY, 44(13), S4.
    DOI WoS1
    2011 Vinodmahato, R., Gyawali, P., Raut, P., Regmi, P., Singh, K., Pandeya, D., & Gyawali, P. (2011). Association between glycaemic control and serum lipid profile in type 2 diabetic patients: Glycated haemoglobin as a dual biomarker. Biomedical Research, 22(3), 375-380.
    Scopus39 WoS28
    2010 Upadhyay, R. B., Carnelio, S., Shenoy, R. P., Gyawali, P., & Mukherjee, M. (2010). Oxidative stress and antioxidant defense in oral lichen planus and oral lichenoid reaction. Scandinavian Journal of Clinical and Laboratory Investigation, 70(4), 225-228.
    DOI Scopus28 WoS21 Europe PMC20
    2010 Aryal, M., Gyawali, P., Rajbhandhari, N., Aryal, P., & Pandeya, D. (2010). A prevalence of thyroid dysfunction in Kathmandu University Hospital, Nepal. Biomedical Research, 21(4), 411-415.
    Scopus19 WoS11
    2010 Aryal, M., Poudel, A., Satyal, B., Gyawali, P., Pokheral, B., Raut, B., . . . Koju, R. (2010). Evaluation of non-HDL-c and total cholesterol: HDL-c ratio as cumulative marker of cardiovascular risk in diabetes mellitus. Kathmandu University Medical Journal, 8(4), 398-404.
    DOI Scopus7 Europe PMC3
    Basnyat, A. S., Prabin Gyawali, P., Jha, A., Risal, P., & Shrestha, B. G. (n.d.). Evaluation of Serum Lipids and C-peptide among Breast Cancer Patients with Chemotherapy. Annals of Clinical Chemistry and Laboratory Medicine, 2(2), 8-14.
    DOI
  • Conference Papers

    Year Citation
    2013 Gyawali, P., Takanche S, J., Acharya, D., & Koju, R. (2013). Serum lipid ratios, on-HDL-cholestrol & atherogenic index of plasma as a predictor of coronary artery disease in patients with metabolic syndrome. In Diabetes Metab J. Seoul, South Korea.
    2012 Gyawali, P., Shrestha, R. K., & Bhattarai, P. (2012). Pattern of thyroid dysfunction in patients with metabolic syndrome. In Endocrine Abstracts. Florence, Italy.
    2012 Gyawali, P., Bajracharya, D., Bhattarai, P., & Shrestha, R. K. (2012). Assessment of practice test significant change and clinical decision limit among practicing physicians in healthcare institutions in Kathmandu valley, Nepal. In Australasian Association of Clinical Biochemists. Melbourne, Australia.
    2011 Gyawali, P., Shrestha, R. K., Aryal, P., & Aryal, M. (2011). Correlation between estimated average glucose levels and fasting plasma glucose levels for diabetes management. In International Diabetes Federation. Dubai, UAE.
  • Conference Items

    Year Citation
    2017 Gyawali, P., Martin, S. A., Heilbronn, L. K., Taylor, A. W., Adams, R. J., O Loughlin, P. D., & Wittert, G. A. (2017). Cross-sectional and longitudinal determinants of serum sex hormone binding globulin (SHBG) in community-dwelling men: the Men Androgen Inflammation Lifestyle Environment and Stress (MAILES) study. Poster session presented at the meeting of CLINICAL ENDOCRINOLOGY. WILEY-BLACKWELL 111 RIVER ST, HOBOKEN 07030-5774, NJ USA: WILEY-BLACKWELL.
    2017 Gyawali, P., Martin, S. A., Heilbronn, L. K., Taylor, A. W., Adams, R. J. T., O'Loughlin, P. D., & Wittert, G. A. (2017). CROSS-SECTIONAL AND LONGITUDINAL DETERMINANTS OF SERUM SEX HORMONE BINDING GLOBULIN (SHBG) IN COMMUNITY-DWELLING MEN: THE MEN ANDROGEN INFLAMMATION LIFESTYLE ENVIRONMENT AND STRESS (MAILES) STUDY. Poster session presented at the meeting of JOURNAL OF SEXUAL MEDICINE. WILEY.
  • Position: Research Officer
  • Phone: 83130514
  • Email: prabin.gyawali@adelaide.edu.au
  • Fax: 8313 0355
  • Campus: North Terrace
  • Building: Adelaide Health and Medical Sciences, floor 6
  • Room: WS6062.24
  • Org Unit: Robinson Research Institute

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