2025 |
Hindes, M. T., McElligott, A. M., Best, O. G., Ward, M. P., Selemidis, S., Miles, M. A., . . . Brooks, D. A. (2025). Metabolic reprogramming, malignant transformation and metastasis: Lessons from chronic lymphocytic leukaemia and prostate cancer. Cancer Letters, 611, 18 pages. DOI |
2025 |
Nturubika, B. D. D., Logan, J., Johnson, I. R. D., Moore, C., Li, K. L., Tang, J., . . . Brooks, D. A. (2025). Components of the Endosome-Lysosome Vesicular Machinery as Drivers of the Metastatic Cascade in Prostate Cancer. Cancers, 17(1), 31 pages. DOI |
2025 |
Orang, A., Warnock, N. I., Migault, M., Dredge, B. K., Bert, A. G., Bracken, J. M., . . . Bracken, C. P. (2025). Chasing non-existent "microRNAs" in cancer.. Oncogenesis, 14(1), 10. DOI |
2024 |
Bracken, C. P., Goodall, G. J., & Gregory, P. A. (2024). RNA regulatory mechanisms controlling TGF-β signaling and EMT in cancer (vol 102, pg 4, 2024). SEMINARS IN CANCER BIOLOGY, 106, 13-14. DOI |
2024 |
Liu, D., Dredge, B. K., Bert, A. G., Pillman, K. A., Toubia, J., Guo, W., . . . Goodall, G. J. (2024). ESRP1 controls biogenesis and function of a large abundant multiexon circRNA. Nucleic Acids Research, 52(3), 1387-1403. DOI Scopus6 Europe PMC6 |
2024 |
Neumann, D. P., Phillips, C. A., Lumb, R., Palethorpe, H. M., Ramani, Y., Hollier, B. G., . . . Gregory, P. A. (2024). Quaking isoforms cooperate to promote the mesenchymal phenotype. Molecular biology of the cell, 35(2), ar17-1-ar17-12. DOI Scopus2 Europe PMC2 |
2024 |
Neumann, D. P., Pillman, K. A., Dredge, B. K., Bert, A. G., Phillips, C. A., Lumb, R., . . . Gregory, P. A. (2024). The landscape of alternative polyadenylation during EMT and its regulation by the RNA-binding protein Quaking. RNA Biology, 21(1), 1-11. DOI Scopus6 Europe PMC5 |
2024 |
Thompson, E. J., Escarbe, S., Tvorogov, D., Farshid, G., Gregory, P. A., Khew-Goodall, Y., . . . Bonder, C. S. (2024). Interleukin-3 production by basal-like breast cancer cells is associated with poor prognosis. Growth Factors, 42(2), 49-61. DOI |
2024 |
Bracken, C. P., Goodall, G. J., & Gregory, P. A. (2024). RNA regulatory mechanisms controlling TGF-β signaling and EMT in cancer. Seminars in Cancer Biology, 102-103, 4-16. DOI Scopus5 Europe PMC2 |
2024 |
Nturubika, B. D., Guardia, C. M., Gershlick, D. C., Logan, J. M., Martini, C., Heatlie, J. K., . . . Johnson, I. R. D. (2024). Altered expression of vesicular trafficking machinery in prostate cancer affects lysosomal dynamics and provides insight into the underlying biology and disease progression. British Journal of Cancer, 131(8), 1263-1278. DOI Scopus2 Europe PMC2 |
2023 |
Sapkota, S., Pillman, K. A., Dredge, B. K., Liu, D., Bracken, J. M., Kachooei, S. A., . . . Goodall, G. J. (2023). On the rules of engagement for microRNAs targeting protein coding regions. Nucleic Acids Research, 51(18), 9938-9951. DOI Scopus7 Europe PMC7 |
2023 |
Orang, A., Dredge, B. K., Liu, C. Y., Bracken, J. M., Chen, C. -H., Sourdin, L., . . . Bracken, C. P. (2023). Basonuclin-2 regulates extracellular matrix production and degradation. Life Science Alliance, 6(10), e202301984-1-e202301984-17. DOI Scopus1 Europe PMC3 |
2023 |
King, J., Evans, C., Kadolsky, U., Norret, M., Iqbal, M., Mercé, C., . . . Smith, N. (2023). Metastable Intermediates Identified in Epithelial to Mesenchymal Transition are Regulated by G-Quadruplex DNA Structures. DOI Europe PMC1 |
2022 |
Tang, Y. H., Rockstroh, A., Sokolowski, K. A., Lynam, L. R., Lehman, M., Thompson, E. W., . . . Hollier, B. G. (2022). Neuropilin-1 is over-expressed in claudin-low breast cancer and promotes tumor progression through acquisition of stem cell characteristics and RAS/MAPK pathway activation. Breast Cancer Research, 24(1), 17 pages. DOI Scopus19 WoS8 Europe PMC15 |
2022 |
Neumann, D. P., Goodall, G. J., & Gregory, P. A. (2022). The Quaking RNA-binding proteins as regulators of cell differentiation. Wiley interdisciplinary reviews. RNA, 13(6), e1724-1-e1724-19. DOI Scopus22 WoS4 Europe PMC23 |
2022 |
Chi, L. H., Cross, R. S. N., Redvers, R. P., Davis, M., Hediyeh-Zadeh, S., Mathivanan, S., . . . Anderson, R. L. (2022). MicroRNA-21 is immunosuppressive and pro-metastatic via separate mechanisms. Oncogenesis, 11(1), 1-12. DOI Scopus19 WoS4 Europe PMC16 |
2021 |
Fernandes, R. C., Toubia, J., Townley, S., Hanson, A. R., Dredge, B. K., Pillman, K. A., . . . Selth, L. A. (2021). Post-transcriptional gene regulation by microRNA-194 promotes neuroendocrine transdifferentiation in prostate cancer. Cell Reports, 34(1), 1-17. DOI Scopus35 WoS23 Europe PMC30 |
2021 |
Chan, K. M., Gleadle, J. M., Gregory, P. A., Phillips, C. A., Safizadeh Shirazi, H., Whiteley, A., . . . Macgregor, M. (2021). Selective microfluidic capture and detection of prostate cancer cells from urine without digital rectal examination. Cancers, 13(21), 5544-1-5544-17. DOI Scopus9 WoS5 Europe PMC7 |
2020 |
Saunders, K., Bert, A. G., Dredge, B. K., Toubia, J., Gregory, P. A., Pillman, K. A., . . . Bracken, C. P. (2020). Insufficiently complex unique-molecular identifiers (UMIs) distort small RNA sequencing. Scientific Reports, 10(1), 1-9. DOI Scopus11 WoS5 Europe PMC8 |
2019 |
Pillman, K. A., Scheer, K. G., Hackett-Jones, E., Saunders, K., Bert, A. G., Toubia, J., . . . Bracken, C. P. (2019). Extensive transcriptional responses are co-ordinated by microRNAs as revealed by Exon-Intron Split Analysis (EISA). Nucleic Acids Research, 47(16), 14 pages. DOI Scopus6 WoS5 Europe PMC5 |
2019 |
Gregory, P. A. (2019). The miR-200-Quaking axis functions in tumour angiogenesis. Oncogene, 38(41), 6767-6769. DOI Scopus4 WoS2 Europe PMC3 |
2019 |
Pinweha, P., Phillips, C. A., Gregory, P. A., Li, X., Chuayboonya, P., Mongkolsiri, P., . . . Jitrapakdee, S. (2019). MicroRNA-143-3p targets pyruvate carboxylase expression and controls proliferation and migration of MDA-MB-231 cells. Archives of Biochemistry and Biophysics, 677, 10 pages. DOI Scopus15 WoS15 Europe PMC10 |
2018 |
Cursons, J., Pillman, K. A., Scheer, K. G., Gregory, P. A., Foroutan, M., Hediyeh-Zadeh, S., . . . Davis, M. J. (2018). Combinatorial targeting by MicroRNAs co-ordinates post-transcriptional control of EMT. Cell Systems, 7(1), 77-91. DOI Scopus72 WoS58 Europe PMC51 |
2018 |
Pillman, K. A., Phillips, C. A., Roslan, S., Toubia, J., Dredge, B. K., Bert, A. G., . . . Gregory, P. A. (2018). miR-200/375 control epithelial plasticity-associated alternative splicing by repressing the RNA-binding protein Quaking. EMBO Journal, 37(13), 20 pages. DOI Scopus86 WoS64 Europe PMC68 |
2018 |
Neumann, D. P., Goodall, G. J., & Gregory, P. A. (2018). Regulation of splicing and circularisation of RNA in epithelial mesenchymal plasticity. Seminars in Cell and Developmental Biology, 75, 50-60. DOI Scopus22 WoS14 Europe PMC18 |
2017 |
Selth, L., Das, R., Townley, S., Coutinho, I., Hanson, A., Centenera, M., . . . Tilley, W. (2017). A ZEB1-miR-375-YAP1 pathway regulates epithelial plasticity in prostate cancer. Oncogene, 36(1), 24-34. DOI Scopus93 WoS84 Europe PMC71 |
2017 |
Das, R., Gregory, P. A., Fernandes, R. C., Denis, I., Wang, Q., Townley, S. L., . . . Selth, L. A. (2017). MicroRNA-194 promotes prostate cancer metastasis by inhibiting SOCS2. Cancer Research, 77(4), 1021-1034. DOI Scopus99 WoS88 Europe PMC76 |
2017 |
Tse, B., Volpert, M., Ratther, E., Stylianou, N., Nouri, M., McGowan, K., . . . Hollier, B. (2017). Neuropilin-1 is upregulated in the adaptive response of prostate tumors to androgen-targeted therapies and is prognostic of metastatic progression and patient mortality. Oncogene, 36(24), 3417-3427. DOI Scopus62 WoS53 Europe PMC51 |
2017 |
Cursons, J., Pillman, K., Scheer, K., Gregory, P., Foroutan, M., Zadeh, S. H., . . . Davis, M. (2017). Post-transcriptional control of EMT is coordinated through combinatorial targeting by multiple microRNAs. DOI |
2015 |
Conn, S., Pillman, K., Toubia, J., Conn, V., Salmanidis, M., Phillips, C., . . . Goodall, G. (2015). The RNA binding protein quaking regulates formation of circRNAs. Cell, 160(6), 1125-1134. DOI Scopus1705 WoS1418 Europe PMC1320 |
2014 |
Das, R., Gregory, P., Hollier, B., Tilley, W., & Selth, L. (2014). Epithelial plasticity in prostate cancer: principles and clinical perspectives. Trends in Molecular Medicine, 20(11), 643-651. DOI Scopus21 WoS20 Europe PMC16 |
2014 |
Young, J. A., Ting, K. K., Li, J., Moller, T., Dunn, L., Lu, Y., . . . Gamble, J. R. (2014). Erratum: Regulation of vascular leak and recovery from ischemic injury by general and VE-cadherin-restricted mirna antagonists of mir-27 (Blood (2012) 122:16 (2911-2919)). Blood, 124(19), 3034. DOI |
2014 |
Zafar, A., Wu, F., Hardy, K., Li, J., Juan Tu, W., McCuaig, R., . . . Rao, S. (2014). Chromatinized protein kinase C-θ directly regulates inducible genes in epithelial to mesenchymal transition and breast cancer stem cells. Molecular and Cellular Biology, 34(16), 2961-2980. DOI Scopus32 WoS30 Europe PMC29 |
2014 |
Bracken, C. P., Li, X., Wright, J. A., Lawrence, D., Pillman, K. A., Salmanidis, M., . . . Goodall, G. (2014). Genome-wide identification of miR-200 targets reveals a regulatory network controlling cell invasion. The EMBO Journal, 33(18), 1979-2134. DOI Scopus123 WoS116 Europe PMC102 |
2014 |
Kolesnikoff, N., Attema, J., Roslan, S., Bert, A., Schwarz, Q., Gregory, P., & Goodall, G. (2014). Specificity protein 1 (Sp1) maintains basal epithelial expression of the miR-200 family: implications for epithelial-mesenchymal transition. Journal of Biological Chemistry, 289(16), 11194-11205. DOI Scopus61 WoS52 Europe PMC45 |
2014 |
Yip, K., Kolesnikoff, N., Yu, C., Hauschild, N., Taing, H., Biggs, L., . . . Grimbaldeston, M. (2014). Mechanisms of vitamin D₃ metabolite repression of IgE-dependent mast cell activation. Journal of Allergy and Clinical Immunology, 133(5), 1356-1379. DOI Scopus99 WoS84 Europe PMC69 |
2014 |
Li, X., Roslan, S., Johnstone, C., Wright, J., Bracken, C., Anderson, M., . . . Khew-Goodall, Y. (2014). MiR-200 can repress breast cancer metastasis through ZEB1-independent but moesin-dependent pathways. Oncogene, 33(31), 4077-4088. DOI Scopus106 WoS93 Europe PMC90 |
2013 |
Young, J., Ting, K., Li, J., Moller, T., Dunn, L., Lu, Y., . . . Gamble, J. (2013). Regulation of vascular leak and recovery from ischemic injury by general and VE-cadherin-restricted miRNA antagonists of miR-27. Blood, 122(16), 2911-2919. DOI Scopus62 WoS54 Europe PMC50 |
2013 |
Lim, Y., Wright, J., Attema, J., Gregory, P., Bert, A., Smith, E., . . . Goodall, G. (2013). Epigenetic modulation of the miR-200 family is associated with transition to a breast cancer stem-cell-like state. Journal of Cell Science, 126(10), 2256-2266. DOI Scopus171 WoS154 Europe PMC135 |
2013 |
Neilsen, P., Noll, J., Mattiske, S., Bracken, C., Gregory, P., Schulz, R., . . . Callen, D. (2013). Mutant p53 drives invasion in breast tumors through up-regulation of miR-155. Oncogene, 32(24), 2992-3000. DOI Scopus152 WoS127 Europe PMC119 |
2013 |
Yu, Y., Gray, B., Lowe, H., Halmagyi, G. M., & Ng, M. (2013). Dual modality intravascular imaging of unstable, symptomatic but "hemodynamically insignificant" carotid stenosis. Journal of Neurology, 260(7), 1934-1935. DOI |
2012 |
Ahn, Y., Gibbons, D., Chakravarti, D., Creighton, C., Rizvi, Z., Adams, H., . . . Kurie, J. (2012). ZEB1 drives prometastatic actin cytoskeletal remodeling by downregulating miR-34a expression. Journal of Clinical Investigation, 122(9), 3170-3183. DOI Scopus139 WoS132 Europe PMC124 |
2012 |
Callegari, S., Gregory, P., Sykes, M., Bellon, J., Andrews, S., McKinnon, R., & de Barros Lopes, M. (2012). Polymorphisms in the mitochondrial ribosome recycling factor EF-G2mt/MEF2 compromise cell respiratory function and increase atorvastatin toxicity. PLoS Genetics, 8(6), 1-12. DOI Scopus5 WoS5 Europe PMC2 |
2011 |
Matsushima, K., Isomoto, H., Yamaguchi, N., Inoue, N., Machida, H., Nakayama, T., . . . Nakao, K. (2011). MiRNA-205 modulates cellular invasion and migration via regulating zinc finger E-box binding homeobox 2 expression in esophageal squamous cell carcinoma cells. Journal of Translational Medicine, 9(30), 1-12. DOI Scopus128 WoS118 Europe PMC98 |
2011 |
Gregory, P., Bracken, C., Smith, E., Bert, A., Wright, J., Roslan, S., . . . Goodall, G. (2011). An autocrine TGF-β/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition. Molecular Biology of the Cell, 22(10), 1686-1698. DOI Scopus499 WoS436 Europe PMC418 |
2011 |
Yang, Y., Ahn, Y., Gibbons, D., Zang, Y., Lin, W., Thilaganathan, N., . . . Kurie, J. (2011). The Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200-dependent pathway in mice. Journal of Clinical Investigation, 121(4), 1373-1385. DOI Scopus181 WoS159 Europe PMC142 |
2010 |
Hu, D., Gardner-Stephen, D., Severi, G., Gregory, P., Treloar, J., Giles, G., . . . MacKenzie, P. (2010). A novel polymorphism in a forkhead box A1 (FOXA1) binding site of the human UDP glucuronosyltransferase 2B17 gene modulates promoter activity and is associated with altered levels of circulating androstane-3α,17β-diol glucuronide. Molecular Pharmacology, 78(4), 714-722. DOI Scopus28 WoS26 Europe PMC24 |
2009 |
Gibbons, D., Lin, W., Creighton, C., Rizvi, Z., Gregory, P., Goodall, G., . . . Kurie, J. (2009). Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression. Genes & Development, 23(18), 2140-2151. DOI Scopus443 WoS383 Europe PMC363 |
2009 |
Bracken, C., Gregory, P., Khew-Goodall, Y., & Goodall, G. (2009). The role of microRNAs in metastasis and epithelial-mesenchymal transition. Cellular and Molecular Life Sciences, 66(10), 1682-1699. DOI Scopus107 WoS94 Europe PMC84 |
2008 |
Paterson, E., Kolesnikoff, N., Gregory, P., Bert, A., Khew-Goodall, Y., & Goodall, G. (2008). The microRNA-200 Family Regulates Epithelial to Mesenchymal Transition. The Scientific World Journal, 8, 901-904. DOI Scopus76 WoS69 Europe PMC58 |
2008 |
Gregory, P., Bracken, C., Bert, A., & Goodall, G. (2008). MicroRNAs as regulators of epithelial-mesenchymal transition. Cell Cycle, 7(20), 3112-3117. DOI Scopus440 WoS393 Europe PMC343 |
2008 |
Bracken, C., Gregory, P., Kolesnikoff, N., Bert, A., Wang, J., Shannon, M., & Goodall, G. (2008). A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition. Cancer Research, 68(19), 7846-7854. DOI Scopus934 WoS846 Europe PMC773 |
2008 |
Gregory, P., Bert, A., Paterson, E., Barry, S., Tsykin, A., Farshid, G., . . . Goodall, G. (2008). The mir-200 family and mir-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nature Cell Biology, 10(5), 593-601. DOI Scopus3392 WoS3067 Europe PMC2709 |
2006 |
Gregory, P. A., Gardner-Stephen, D. A., Rogers, A., Michael, M. Z., & Mackenzie, P. I. (2006). The caudal-related homeodomain protein Cdx2 and hepatocyte nuclear factor 1α cooperatively regulate the UDP-glucuronosyltransferase 2B7 gene promoter. Pharmacogenetics and Genomics, 16(7), 527-536. DOI Scopus21 WoS18 Europe PMC16 |
2005 |
Gardner-Stephen, D. A., Gregory, P. A., & Mackenzie, P. I. (2005). Identification and characterization of functional hepatocyte nuclear factor 1-binding sites in UDP-glucuronosyltransferase genes. Methods in Enzymology, 400, 22-46. DOI Scopus16 Europe PMC12 |
2004 |
Gregory, P. A., Lewinsky, R. H., Gardner-Stephen, D. A., & Mackenzie, P. I. (2004). Regulation of UDP glucuronosyltransferases in the gastrointestinal tract. Toxicology and Applied Pharmacology, 199(3), 354-363. DOI Scopus109 WoS101 Europe PMC77 |
2004 |
Gregory, P. A., Lewinsky, R. H., Gardner-Stephen, D. A., & Mackenzie, P. I. (2004). Coordinate Regulation of the Human UDP-Glucuronosyltransferase 1A8, 1A9, and 1A10 Genes by Hepatocyte Nuclear Factor 1α and the Caudal-Related Homeodomain Protein 2. Molecular Pharmacology, 65(4), 953-963. DOI Scopus69 WoS62 Europe PMC51 |
2003 |
Mackenzie, P. I., Gregory, P. A., Gardner-Stephen, D. A., Lewinsky, R. H., Jorgensen, B. R., Nishiyama, T., . . . Radominska-Pandya, A. (2003). Regulation of UDP glucuronosyltransferase genes. Current Drug Metabolism, 4(3), 249-257. DOI Scopus105 WoS93 Europe PMC67 |
2003 |
Gregory, P. A., Gardner-Stephen, D. A., Lewinsky, R. H., Duncliffe, K. N., & Mackenzie, P. I. (2003). Cloning and characterization of the human UDP-glucuronosyltransferase 1A8, 1A9, and 1A10 gene promoters: Differential regulation through an initiator-like region. Journal of Biological Chemistry, 278(38), 36107-36114. DOI Scopus27 WoS25 Europe PMC20 |
2002 |
Gregory, P. A., & Mackenzie, P. I. (2002). The homeodomain Pbx2-Prep1 complex modulates hepatocyte nuclear factor 1α-mediated activation of the UDP-glucuronosyltransferase 2B17 gene. Molecular Pharmacology, 62(1), 154-161. DOI Scopus29 WoS26 Europe PMC17 |
2000 |
Gregory, P. A., Hansen, A. J., & Mackenzie, P. I. (2000). Tissue specific differences in the regulation of the UDP glucuronosyltransferase 2B17 gene promoter. Pharmacogenetics, 10(9), 809-820. DOI Scopus32 WoS28 Europe PMC17 |