2025 |
Hindes, M. T., McElligott, A. M., Best, O. G., Ward, M. P., Selemidis, S., Miles, M. A., . . . Brooks, D. A. (2025). Metabolic reprogramming, malignant transformation and metastasis: Lessons from chronic lymphocytic leukaemia and prostate cancer. Cancer Letters, 611, 18 pages. DOI |
2025 |
Nturubika, B. D. D., Logan, J., Johnson, I. R. D., Moore, C., Li, K. L., Tang, J., . . . Brooks, D. A. (2025). Components of the Endosome-Lysosome Vesicular Machinery as Drivers of the Metastatic Cascade in Prostate Cancer. Cancers, 17(1), 31 pages. DOI |
2025 |
Orang, A., Warnock, N. I., Migault, M., Dredge, B. K., Bert, A. G., Bracken, J. M., . . . Bracken, C. P. (2025). Chasing non-existent “microRNAs” in cancer. Oncogenesis, 14(1), 9 pages. DOI |
2025 |
Toubia, J., Kusay, Y., Maqsood, M., Warnock, N. I., Lawrence, D. M., Bracken, C. P., . . . Schreiber, A. W. (2025). TRanscriptome ANalysis of StratifiEd CohorTs (TRANSECT) enables automated assessment of global gene regulation linked to disparate expression in user defined genes and gene sets. NAR Genomics and Bioinformatics, 7(2), 13 pages. DOI |
2024 |
Bracken, C. P., Goodall, G. J., & Gregory, P. A. (2024). RNA regulatory mechanisms controlling TGF-β signaling and EMT in cancer (vol 102, pg 4, 2024). SEMINARS IN CANCER BIOLOGY, 106, 13-14. DOI |
2024 |
Liu, D., Dredge, B. K., Bert, A. G., Pillman, K. A., Toubia, J., Guo, W., . . . Goodall, G. J. (2024). ESRP1 controls biogenesis and function of a large abundant multiexon circRNA. Nucleic Acids Research, 52(3), 1387-1403. DOI Scopus8 Europe PMC10 |
2024 |
Neumann, D. P., Phillips, C. A., Lumb, R., Palethorpe, H. M., Ramani, Y., Hollier, B. G., . . . Gregory, P. A. (2024). Quaking isoforms cooperate to promote the mesenchymal phenotype. Molecular biology of the cell, 35(2), ar17-1-ar17-12. DOI Scopus2 Europe PMC2 |
2024 |
Neumann, D. P., Pillman, K. A., Dredge, B. K., Bert, A. G., Phillips, C. A., Lumb, R., . . . Gregory, P. A. (2024). The landscape of alternative polyadenylation during EMT and its regulation by the RNA-binding protein Quaking. RNA Biology, 21(1), 1-11. DOI Scopus6 Europe PMC11 |
2024 |
Thompson, E. J., Escarbe, S., Tvorogov, D., Farshid, G., Gregory, P. A., Khew-Goodall, Y., . . . Bonder, C. S. (2024). Interleukin-3 production by basal-like breast cancer cells is associated with poor prognosis. Growth Factors, 42(2), 49-61. DOI |
2024 |
Bracken, C. P., Goodall, G. J., & Gregory, P. A. (2024). RNA regulatory mechanisms controlling TGF-β signaling and EMT in cancer. Seminars in Cancer Biology, 102-103, 4-16. DOI Scopus6 Europe PMC4 |
2024 |
Nturubika, B. D., Guardia, C. M., Gershlick, D. C., Logan, J. M., Martini, C., Heatlie, J. K., . . . Johnson, I. R. D. (2024). Altered expression of vesicular trafficking machinery in prostate cancer affects lysosomal dynamics and provides insight into the underlying biology and disease progression. British Journal of Cancer, 131(8), 1263-1278. DOI Scopus2 Europe PMC2 |
2023 |
Sapkota, S., Pillman, K. A., Dredge, B. K., Liu, D., Bracken, J. M., Kachooei, S. A., . . . Goodall, G. J. (2023). On the rules of engagement for microRNAs targeting protein coding regions. Nucleic Acids Research, 51(18), 9938-9951. DOI Scopus8 Europe PMC8 |
2023 |
Orang, A., Dredge, B. K., Liu, C. Y., Bracken, J. M., Chen, C. -H., Sourdin, L., . . . Bracken, C. P. (2023). Basonuclin-2 regulates extracellular matrix production and degradation. Life Science Alliance, 6(10), e202301984-1-e202301984-17. DOI Scopus1 Europe PMC3 |
2023 |
King, J., Evans, C., Kadolsky, U., Norret, M., Iqbal, M., Mercé, C., . . . Smith, N. (2023). Metastable Intermediates Identified in Epithelial to Mesenchymal Transition are Regulated by G-Quadruplex DNA Structures. DOI Europe PMC1 |
2022 |
Tang, Y. H., Rockstroh, A., Sokolowski, K. A., Lynam, L. R., Lehman, M., Thompson, E. W., . . . Hollier, B. G. (2022). Neuropilin-1 is over-expressed in claudin-low breast cancer and promotes tumor progression through acquisition of stem cell characteristics and RAS/MAPK pathway activation. Breast Cancer Research, 24(1), 17 pages. DOI Scopus22 WoS8 Europe PMC15 |
2022 |
Neumann, D. P., Goodall, G. J., & Gregory, P. A. (2022). The Quaking RNA-binding proteins as regulators of cell differentiation. Wiley interdisciplinary reviews. RNA, 13(6), e1724-1-e1724-19. DOI Scopus23 WoS4 Europe PMC23 |
2022 |
Chi, L. H., Cross, R. S. N., Redvers, R. P., Davis, M., Hediyeh-Zadeh, S., Mathivanan, S., . . . Anderson, R. L. (2022). MicroRNA-21 is immunosuppressive and pro-metastatic via separate mechanisms. Oncogenesis, 11(1), 1-12. DOI Scopus20 WoS4 Europe PMC17 |
2021 |
Fernandes, R. C., Toubia, J., Townley, S., Hanson, A. R., Dredge, B. K., Pillman, K. A., . . . Selth, L. A. (2021). Post-transcriptional gene regulation by microRNA-194 promotes neuroendocrine transdifferentiation in prostate cancer. Cell Reports, 34(1), 1-17. DOI Scopus36 WoS23 Europe PMC32 |
2021 |
Chan, K. M., Gleadle, J. M., Gregory, P. A., Phillips, C. A., Safizadeh Shirazi, H., Whiteley, A., . . . Macgregor, M. (2021). Selective microfluidic capture and detection of prostate cancer cells from urine without digital rectal examination. Cancers, 13(21), 5544-1-5544-17. DOI Scopus9 WoS5 Europe PMC7 |
2020 |
Saunders, K., Bert, A. G., Dredge, B. K., Toubia, J., Gregory, P. A., Pillman, K. A., . . . Bracken, C. P. (2020). Insufficiently complex unique-molecular identifiers (UMIs) distort small RNA sequencing. Scientific Reports, 10(1), 1-9. DOI Scopus12 WoS5 Europe PMC9 |
2019 |
Pillman, K. A., Scheer, K. G., Hackett-Jones, E., Saunders, K., Bert, A. G., Toubia, J., . . . Bracken, C. P. (2019). Extensive transcriptional responses are co-ordinated by microRNAs as revealed by Exon-Intron Split Analysis (EISA). Nucleic Acids Research, 47(16), 14 pages. DOI Scopus6 WoS5 Europe PMC5 |
2019 |
Gregory, P. A. (2019). The miR-200-Quaking axis functions in tumour angiogenesis. Oncogene, 38(41), 6767-6769. DOI Scopus4 WoS2 Europe PMC3 |
2019 |
Pinweha, P., Phillips, C. A., Gregory, P. A., Li, X., Chuayboonya, P., Mongkolsiri, P., . . . Jitrapakdee, S. (2019). MicroRNA-143-3p targets pyruvate carboxylase expression and controls proliferation and migration of MDA-MB-231 cells. Archives of Biochemistry and Biophysics, 677, 10 pages. DOI Scopus15 WoS15 Europe PMC11 |
2018 |
Cursons, J., Pillman, K. A., Scheer, K. G., Gregory, P. A., Foroutan, M., Hediyeh-Zadeh, S., . . . Davis, M. J. (2018). Combinatorial targeting by MicroRNAs co-ordinates post-transcriptional control of EMT. Cell Systems, 7(1), 77-91. DOI Scopus73 WoS58 Europe PMC56 |
2018 |
Pillman, K. A., Phillips, C. A., Roslan, S., Toubia, J., Dredge, B. K., Bert, A. G., . . . Gregory, P. A. (2018). miR-200/375 control epithelial plasticity-associated alternative splicing by repressing the RNA-binding protein Quaking. EMBO Journal, 37(13), 20 pages. DOI Scopus86 WoS64 Europe PMC68 |
2018 |
Neumann, D. P., Goodall, G. J., & Gregory, P. A. (2018). Regulation of splicing and circularisation of RNA in epithelial mesenchymal plasticity. Seminars in Cell and Developmental Biology, 75, 50-60. DOI Scopus22 WoS14 Europe PMC18 |
2017 |
Selth, L., Das, R., Townley, S., Coutinho, I., Hanson, A., Centenera, M., . . . Tilley, W. (2017). A ZEB1-miR-375-YAP1 pathway regulates epithelial plasticity in prostate cancer. Oncogene, 36(1), 24-34. DOI Scopus93 WoS84 Europe PMC74 |
2017 |
Das, R., Gregory, P. A., Fernandes, R. C., Denis, I., Wang, Q., Townley, S. L., . . . Selth, L. A. (2017). MicroRNA-194 promotes prostate cancer metastasis by inhibiting SOCS2. Cancer Research, 77(4), 1021-1034. DOI Scopus99 WoS88 Europe PMC79 |
2017 |
Tse, B., Volpert, M., Ratther, E., Stylianou, N., Nouri, M., McGowan, K., . . . Hollier, B. (2017). Neuropilin-1 is upregulated in the adaptive response of prostate tumors to androgen-targeted therapies and is prognostic of metastatic progression and patient mortality. Oncogene, 36(24), 3417-3427. DOI Scopus62 WoS53 Europe PMC52 |
2017 |
Cursons, J., Pillman, K., Scheer, K., Gregory, P., Foroutan, M., Zadeh, S. H., . . . Davis, M. (2017). Post-transcriptional control of EMT is coordinated through combinatorial targeting by multiple microRNAs. DOI |
2015 |
Conn, S., Pillman, K., Toubia, J., Conn, V., Salmanidis, M., Phillips, C., . . . Goodall, G. (2015). The RNA binding protein quaking regulates formation of circRNAs. Cell, 160(6), 1125-1134. DOI Scopus1716 WoS1418 Europe PMC1402 |
2014 |
Das, R., Gregory, P., Hollier, B., Tilley, W., & Selth, L. (2014). Epithelial plasticity in prostate cancer: principles and clinical perspectives. Trends in Molecular Medicine, 20(11), 643-651. DOI Scopus21 WoS20 Europe PMC16 |
2014 |
Young, J. A., Ting, K. K., Li, J., Moller, T., Dunn, L., Lu, Y., . . . Gamble, J. R. (2014). Erratum: Regulation of vascular leak and recovery from ischemic injury by general and VE-cadherin-restricted mirna antagonists of mir-27 (Blood (2012) 122:16 (2911-2919)). Blood, 124(19), 3034. DOI |
2014 |
Zafar, A., Wu, F., Hardy, K., Li, J., Juan Tu, W., McCuaig, R., . . . Rao, S. (2014). Chromatinized protein kinase C-θ directly regulates inducible genes in epithelial to mesenchymal transition and breast cancer stem cells. Molecular and Cellular Biology, 34(16), 2961-2980. DOI Scopus32 WoS30 Europe PMC29 |
2014 |
Bracken, C. P., Li, X., Wright, J. A., Lawrence, D., Pillman, K. A., Salmanidis, M., . . . Goodall, G. (2014). Genome-wide identification of miR-200 targets reveals a regulatory network controlling cell invasion. The EMBO Journal, 33(18), 1979-2134. DOI Scopus123 WoS116 Europe PMC105 |
2014 |
Kolesnikoff, N., Attema, J., Roslan, S., Bert, A., Schwarz, Q., Gregory, P., & Goodall, G. (2014). Specificity protein 1 (Sp1) maintains basal epithelial expression of the miR-200 family: implications for epithelial-mesenchymal transition. Journal of Biological Chemistry, 289(16), 11194-11205. DOI Scopus61 WoS52 Europe PMC45 |
2014 |
Yip, K., Kolesnikoff, N., Yu, C., Hauschild, N., Taing, H., Biggs, L., . . . Grimbaldeston, M. (2014). Mechanisms of vitamin D₃ metabolite repression of IgE-dependent mast cell activation. Journal of Allergy and Clinical Immunology, 133(5), 1356-1379. DOI Scopus99 WoS84 Europe PMC71 |
2014 |
Li, X., Roslan, S., Johnstone, C., Wright, J., Bracken, C., Anderson, M., . . . Khew-Goodall, Y. (2014). MiR-200 can repress breast cancer metastasis through ZEB1-independent but moesin-dependent pathways. Oncogene, 33(31), 4077-4088. DOI Scopus106 WoS93 Europe PMC91 |
2013 |
Young, J., Ting, K., Li, J., Moller, T., Dunn, L., Lu, Y., . . . Gamble, J. (2013). Regulation of vascular leak and recovery from ischemic injury by general and VE-cadherin-restricted miRNA antagonists of miR-27. Blood, 122(16), 2911-2919. DOI Scopus62 WoS54 Europe PMC50 |
2013 |
Lim, Y., Wright, J., Attema, J., Gregory, P., Bert, A., Smith, E., . . . Goodall, G. (2013). Epigenetic modulation of the miR-200 family is associated with transition to a breast cancer stem-cell-like state. Journal of Cell Science, 126(10), 2256-2266. DOI Scopus171 WoS154 Europe PMC135 |
2013 |
Neilsen, P., Noll, J., Mattiske, S., Bracken, C., Gregory, P., Schulz, R., . . . Callen, D. (2013). Mutant p53 drives invasion in breast tumors through up-regulation of miR-155. Oncogene, 32(24), 2992-3000. DOI Scopus152 WoS127 Europe PMC124 |
2013 |
Yu, Y., Gray, B., Lowe, H., Halmagyi, G. M., & Ng, M. (2013). Dual modality intravascular imaging of unstable, symptomatic but "hemodynamically insignificant" carotid stenosis. Journal of Neurology, 260(7), 1934-1935. DOI |
2012 |
Ahn, Y., Gibbons, D., Chakravarti, D., Creighton, C., Rizvi, Z., Adams, H., . . . Kurie, J. (2012). ZEB1 drives prometastatic actin cytoskeletal remodeling by downregulating miR-34a expression. Journal of Clinical Investigation, 122(9), 3170-3183. DOI Scopus140 WoS132 Europe PMC127 |
2012 |
Callegari, S., Gregory, P., Sykes, M., Bellon, J., Andrews, S., McKinnon, R., & de Barros Lopes, M. (2012). Polymorphisms in the mitochondrial ribosome recycling factor EF-G2mt/MEF2 compromise cell respiratory function and increase atorvastatin toxicity. PLoS Genetics, 8(6), 1-12. DOI Scopus5 WoS5 Europe PMC5 |
2011 |
Matsushima, K., Isomoto, H., Yamaguchi, N., Inoue, N., Machida, H., Nakayama, T., . . . Nakao, K. (2011). MiRNA-205 modulates cellular invasion and migration via regulating zinc finger E-box binding homeobox 2 expression in esophageal squamous cell carcinoma cells. Journal of Translational Medicine, 9(30), 1-12. DOI Scopus128 WoS118 Europe PMC99 |
2011 |
Gregory, P., Bracken, C., Smith, E., Bert, A., Wright, J., Roslan, S., . . . Goodall, G. (2011). An autocrine TGF-β/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition. Molecular Biology of the Cell, 22(10), 1686-1698. DOI Scopus500 WoS436 Europe PMC422 |
2011 |
Yang, Y., Ahn, Y., Gibbons, D., Zang, Y., Lin, W., Thilaganathan, N., . . . Kurie, J. (2011). The Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200-dependent pathway in mice. Journal of Clinical Investigation, 121(4), 1373-1385. DOI Scopus181 WoS159 Europe PMC143 |
2010 |
Hu, D., Gardner-Stephen, D., Severi, G., Gregory, P., Treloar, J., Giles, G., . . . MacKenzie, P. (2010). A novel polymorphism in a forkhead box A1 (FOXA1) binding site of the human UDP glucuronosyltransferase 2B17 gene modulates promoter activity and is associated with altered levels of circulating androstane-3α,17β-diol glucuronide. Molecular Pharmacology, 78(4), 714-722. DOI Scopus28 WoS26 Europe PMC25 |
2009 |
Gibbons, D., Lin, W., Creighton, C., Rizvi, Z., Gregory, P., Goodall, G., . . . Kurie, J. (2009). Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression. Genes & Development, 23(18), 2140-2151. DOI Scopus444 WoS383 Europe PMC370 |
2009 |
Bracken, C., Gregory, P., Khew-Goodall, Y., & Goodall, G. (2009). The role of microRNAs in metastasis and epithelial-mesenchymal transition. Cellular and Molecular Life Sciences, 66(10), 1682-1699. DOI Scopus107 WoS94 Europe PMC87 |
2008 |
Paterson, E., Kolesnikoff, N., Gregory, P., Bert, A., Khew-Goodall, Y., & Goodall, G. (2008). The microRNA-200 Family Regulates Epithelial to Mesenchymal Transition. The Scientific World Journal, 8, 901-904. DOI Scopus76 WoS69 Europe PMC58 |
2008 |
Gregory, P., Bracken, C., Bert, A., & Goodall, G. (2008). MicroRNAs as regulators of epithelial-mesenchymal transition. Cell Cycle, 7(20), 3112-3117. DOI Scopus440 WoS393 Europe PMC356 |
2008 |
Bracken, C., Gregory, P., Kolesnikoff, N., Bert, A., Wang, J., Shannon, M., & Goodall, G. (2008). A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition. Cancer Research, 68(19), 7846-7854. DOI Scopus939 WoS846 Europe PMC800 |
2008 |
Gregory, P., Bert, A., Paterson, E., Barry, S., Tsykin, A., Farshid, G., . . . Goodall, G. (2008). The mir-200 family and mir-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nature Cell Biology, 10(5), 593-601. DOI Scopus3395 WoS3067 Europe PMC2798 |
2006 |
Gregory, P. A., Gardner-Stephen, D. A., Rogers, A., Michael, M. Z., & Mackenzie, P. I. (2006). The caudal-related homeodomain protein Cdx2 and hepatocyte nuclear factor 1α cooperatively regulate the UDP-glucuronosyltransferase 2B7 gene promoter. Pharmacogenetics and Genomics, 16(7), 527-536. DOI Scopus21 WoS18 Europe PMC16 |
2005 |
Gardner-Stephen, D. A., Gregory, P. A., & Mackenzie, P. I. (2005). Identification and characterization of functional hepatocyte nuclear factor 1-binding sites in UDP-glucuronosyltransferase genes. Methods in Enzymology, 400, 22-46. DOI Scopus16 Europe PMC12 |
2004 |
Gregory, P. A., Lewinsky, R. H., Gardner-Stephen, D. A., & Mackenzie, P. I. (2004). Regulation of UDP glucuronosyltransferases in the gastrointestinal tract. Toxicology and Applied Pharmacology, 199(3), 354-363. DOI Scopus109 WoS101 Europe PMC79 |
2004 |
Gregory, P. A., Lewinsky, R. H., Gardner-Stephen, D. A., & Mackenzie, P. I. (2004). Coordinate Regulation of the Human UDP-Glucuronosyltransferase 1A8, 1A9, and 1A10 Genes by Hepatocyte Nuclear Factor 1α and the Caudal-Related Homeodomain Protein 2. Molecular Pharmacology, 65(4), 953-963. DOI Scopus69 WoS62 Europe PMC51 |
2003 |
Mackenzie, P. I., Gregory, P. A., Gardner-Stephen, D. A., Lewinsky, R. H., Jorgensen, B. R., Nishiyama, T., . . . Radominska-Pandya, A. (2003). Regulation of UDP glucuronosyltransferase genes. Current Drug Metabolism, 4(3), 249-257. DOI Scopus106 WoS93 Europe PMC72 |
2003 |
Gregory, P. A., Gardner-Stephen, D. A., Lewinsky, R. H., Duncliffe, K. N., & Mackenzie, P. I. (2003). Cloning and characterization of the human UDP-glucuronosyltransferase 1A8, 1A9, and 1A10 gene promoters: Differential regulation through an initiator-like region. Journal of Biological Chemistry, 278(38), 36107-36114. DOI Scopus27 WoS25 Europe PMC20 |
2002 |
Gregory, P. A., & Mackenzie, P. I. (2002). The homeodomain Pbx2-Prep1 complex modulates hepatocyte nuclear factor 1α-mediated activation of the UDP-glucuronosyltransferase 2B17 gene. Molecular Pharmacology, 62(1), 154-161. DOI Scopus29 WoS26 Europe PMC17 |
2000 |
Gregory, P. A., Hansen, A. J., & Mackenzie, P. I. (2000). Tissue specific differences in the regulation of the UDP glucuronosyltransferase 2B17 gene promoter. Pharmacogenetics, 10(9), 809-820. DOI Scopus32 WoS28 Europe PMC19 |