Dr Oveis Pourmehran
Grant-Funded Researcher (A)
Adelaide Medical School
Faculty of Health and Medical Sciences
Eligible to supervise Masters and PhD - email supervisor to discuss availability.
Oveis Pourmehran began his research journey in targeted drug delivery during his Master's program (2013-2015), where he developed several computational fluid dynamics (CFD) models to simulate magnetic drug targeting, thereby enhancing drug delivery efficiency in the human lungs.
In 2017, Oveis joined the University of Adelaide (Australia) as a Ph.D. candidate and completed his thesis titled "Understanding the flow behaviour in human maxillary sinuses for drug delivery applications" at the School of Mechanical Engineering in 2021. His Ph.D. research contributed to the advancement of a tailored acoustic wave technique for drug delivery to human sinuses. In this groundbreaking work, he developed a high-fidelity direct computational aero-acoustic model to investigate the effect of acoustic waves on drug delivery to human maxillary sinuses, providing new insights into the acoustic drug delivery technique. His experiments demonstrated the potential of this technique to increase drug delivery efficiency by more than 45 times compared to conventional nebulized drug delivery methods.
Since June 2021, Oveis has been a postdoctoral research fellow at the Department of Otolaryngology, Head and Neck Surgery, Adelaide Medical School, University of Adelaide, where he established a Biomechanics Research Node (ENT-BioMech) to develop innovative drug delivery methods and devices for enhancing treatment efficiency in human upper airway diseases. Collaborating with leading researchers and scientists from the ENT research group at the medical school and researchers at the School of Mechanical Engineering, he has been awarded several research grants totaling over $2 million as a chief investigator to develop cutting-edge techniques and devices for drug delivery to the upper airways and sinuses for CF and CRS treatment.
Media appearances:
https://set.adelaide.edu.au/news/list/2022/02/18/mechanical-engineering-phd-concept-developed-for-use-in-medical-clinical
https://www.schoolandcollegelistings.com/AU/Adelaide/321219921227571/Basil-Hetzel-Institute-for-Translational-Health-Research
- My Research
- Career
- Publications
- Grants and Funding
- Teaching
- Supervision
- Professional Activities
- Contact
As a multidisciplinary research team, the ENT surgery group, led by Prof. Peter-John Wormald, has recently established a Biomedical Engineering research node under the supervision of Oveis Pourmehran. The research node aims to develop innovative drug delivery methods and devices to improve treatment efficiency for upper airway diseases.
The following research topics are available for Ph.D. applicants, HDR, Honours, and 3rd-year students in 2024:
1. The power of music in sinonasal drug delivery
2. Acoustic drug delivery to paranasal sinuses
3. Development of a mesh nebulizer for improved sinus drug delivery
4. Virtual endoscopic sinus surgery (ESS) followed by airflow analysis and particle tracking in the nasal cavity and paranasal sinuses
5. Magnetic and electric-charged particle (drug) delivery to human lung and paranasal sinuses
Other Projects :
1. Evaluating Nasal Irrigation Flow Dynamics and Eustachian Tube Involvement: A Computational Fluid Dynamics Approach
2. Designing Focused Magnetic Field Systems for Targeted Nasal Cavity Drug Delivery: A Strategy for Frontal and Maxillary Sinuses
3. Sinus Drug Delivery Assessment: 3D Models, FITC, and SPECT Imaging
4. Optimising Microfluidic Methods for Realistic In-vitro Assessment of Sinus Drug Delivery Efficiency
These research projects employ various techniques and skills, including computational fluid dynamics (CFD), particle tracking using DPM-CFD, finite element analysis (FEA), signal processing (acoustics), computer-aided design (CAD) modeling, CT-scan reconstruction (using 3D Slicer and other potential software), and cutting-edge 3D printing technology (such as FUSETEC).
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Appointments
Date Position Institution name 2021 - ongoing Postdoctoral Research Fellow The University of Adelaide 2017 - 2021 PhD candidate The University of Adelaide 2016 - 2017 Lecturer Golestan Institute of Higher Education 2015 - 2017 Lecturer Islamic Azad University of Gorgan 2015 - 2017 Researcher Young Researchers and Elites Club -
Awards and Achievements
Date Type Title Institution Name Country Amount 2024 Award Adelaide Medical School Research Travel Awards The University of Adelaide Australia $1,500 2023 Scholarship 2023 THRFG BHI Conference and Travel Grant The Hospital Research Foundation Group Australia $750 2021 Award Dean's Commendation for Doctoral Thesis Excellence The University of Adelaide Australia - 2020 Award ECMS High-Impact publication in the sector of "Health Solutions" The University of Adelaide Australia - 2020 Award Frank Perry Travelling Scholarship in Engineering The University of Adelaide Australia $1,500 2017 Scholarship Beacon of Enlightenment PhD Scholarship The University of Adelaide Australia $90,000 2015 Award Distinguished Graduated Student National Elite Foundation Iran, Islamic Republic of - -
Education
Date Institution name Country Title 2017 - 2021 The University of Adelaide Australia PhD 2013 - 2015 Babol Noshirvani University of Technology Iran M.Sc -
Certifications
Date Title Institution name Country 2019 ANSYS Fluids Academic Training at University of Adelaide LEAP Australia Pty Ltd Leading Engineering Application Providers Australia 2018 2 Day FEA and CFD ANSYS Academic Training at the University of Adelaide LEAP Australia Pty Ltd Leading Engineering Application Providers Australia -
Research Interests
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Journals
Year Citation 2024 Meymivand, A., Shirani, M., Yamini, Y., Shahhosseini, S., Kashani, M. N., Pourmehran, O., & Vreugde, S. (2024). Polymeric membrane supports in electromembrane extraction: An overview of various options, methodologies, and modifications. TrAC - Trends in Analytical Chemistry, 181, 117994.
2023 Farnoud, A., Tofighian, H., Baumann, I., Ahookhosh, K., Pourmehran, O., Cui, X., . . . Schmid, O. (2023). Numerical and Machine Learning Analysis of the Parameters Affecting the Regionally Delivered Nasal Dose of Nano- and Micro-Sized Aerosolized Drugs. Pharmaceuticals, 16(1), 81-1-81-14.
Scopus6 Europe PMC12023 Pourmehran, O., Zarei, K., Pourchez, J., Vreugde, S., Psaltis, A., & Wormald, P. -J. (2023). Advancements in Acoustic Drug Delivery for Paranasal Sinuses: A Comprehensive Review. International Journal of Pharmaceutics, 644, 123277-1-123277-18.
Scopus3 Europe PMC12022 Pourmehran, O., Cazzolato, B., Tian, Z., & Arjomandi, M. (2022). The effect of inlet flow profile and nozzle diameter on drug delivery to the maxillary sinus. Biomechanics and Modeling in Mechanobiology, 21(3), 849-870.
Scopus9 WoS5 Europe PMC32021 Pourmehran, O., Arjomandi, M., Cazzolato, B., Tian, Z., Vreugde, S., Javadiyan, S., . . . Wormald, P. -J. (2021). Acoustic drug delivery to the maxillary sinus.. Int J Pharm, 606, 1-15.
Scopus18 WoS12 Europe PMC62021 Islam, M. S., Larpruenrudee, P., Saha, S. C., Pourmehran, O., Paul, A. R., Gemci, T., . . . Gu, Y. (2021). How severe acute respiratory syndrome coronavirus-2 aerosol propagates through the age-specific upper airways. Physics of Fluids, 33(8), 081911-1-081911-13.
Scopus29 WoS18 Europe PMC72021 Taheri, M. H., Pourmehran, O., Sarafraz, M. M., Ahookhosh, K., Farnoud, A., & Cui, X. (2021). Effect of swirling flow and particle-release pattern on drug delivery to human tracheobronchial airways. Biomechanics and Modeling in Mechanobiology, 20(6), 2451-2469.
Scopus20 WoS10 Europe PMC92020 Sarafraz, M. M., Pourmehran, O., Yang, B., Arjomandi, M., & Ellahi, R. (2020). Pool boiling heat transfer characteristics of iron oxide nano-suspension under constant magnetic field. International Journal of Thermal Sciences, 147, 106131.
Scopus126 WoS1122020 Ahookhosh, K., Pourmehran, O., Aminfar, H., Mohammadpourfard, M., Sarafraz, M. M., & Hamishehkar, H. (2020). Development of Human Respiratory Airway Models: A Review.. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 145, 1-22.
Scopus62 WoS40 Europe PMC152020 Arya, H., Sarafraz, M. M., Pourmehran, O., & Arjomandi, M. (2020). Performance index improvement of a double-pipe cooler with MgO/water-ethylene glycol (50:50) nano-suspension. Propulsion and Power Research, 9(1), 75-86.
Scopus11 WoS62020 Pourmehran, O., Cazzolato, B., Tian, Z., & Arjomandi, M. (2020). Acoustically-driven drug delivery to maxillary sinuses: aero-acoustic analysis. European Journal of Pharmaceutical Sciences, 151, 1-14.
Scopus21 WoS16 Europe PMC72019 Arya, H., Sarafraz, M. M., Pourmehran, O., & Arjomandi, M. (2019). Heat transfer and pressure drop characteristics of MgO nanofluid in a double pipe heat exchanger. Heat and Mass Transfer, 55(6), 1769-1781.
Scopus37 WoS262019 Sarafraz, M. M., Pourmehran, O., Yang, B., & Arjomandi, M. (2019). Assessment of the thermal performance of a thermosyphon heat pipe using zirconia-acetone nanofluids. Renewable Energy, 136, 884-895.
Scopus121 WoS972019 Sarafraz, M. M., Yang, B., Pourmehran, O., Arjomandi, M., & Ghomashchi, R. (2019). Fluid and heat transfer characteristics of aqueous graphene nanoplatelet (GNP) nanofluid in a microchannel. International Communications in Heat and Mass Transfer, 107, 24-33.
Scopus92 WoS712019 Sarafraz, M. M., Silakhori, M., Madani, S. A., Kiamahalleh, M. V., & Pourmehran, O. (2019). Thermal and hydraulic performance of a heat exchanger working with carbon-water nanofluid. Heat and Mass Transfer/Waerme- und Stoffuebertragung, 55(12), 3443-3453.
Scopus8 WoS72019 Pourmehran, O., Arjomandi, M., Cazzolato, B., Ghanadi, F., & Tian, Z. (2019). The impact of geometrical parameters on acoustically driven drug delivery to maxillary sinuses.. Biomech Model Mechanobiol, 19(2), 557-575.
Scopus15 WoS13 Europe PMC32018 Tabassum, R., Mehmood, R., Pourmehran, O., Akbar, N. S., & Gorji-Bandpy, M. (2018). Impact of viscosity variation on oblique flow of Cu–H2O nanofluid. Proceedings of the Institution of Mechanical Engineers, Part E: Journal of Process Mechanical Engineering, 232(5), 622-631.
Scopus28 WoS222018 Mehmood, R., Tabassum, R., Pourmehran, O., & Ganji, D. D. (2018). Crosswise stream of hydrogen-oxide (H2O) through a porous media containing copper nanoparticles. International Journal of Hydrogen Energy, 43(15), 7562-7569.
Scopus15 WoS152018 Pourmehran, O., Sarafraz, M., Rahimi-Gorji, M., & Ganji, D. (2018). Rheological behaviour of various metal-based nano-fluids between rotating discs: a new insight. Journal of the Taiwan Institute of Chemical Engineers, 88, 37-48.
Scopus69 WoS622018 Sarafraz, M., Pourmehran, O., Nikkhah, V., & Arya, A. (2018). Pool boiling heat transfer to zinc oxide-ethylene glycol nano-suspension near the critical heat flux. Journal of Mechanical Science and Technology, 32(5), 2309-2315.
Scopus11 WoS72018 Tabasum, R., Mehmood, R., & Pourmehran, O. (2018). Velocity slip in mixed convective oblique transport of titanium oxide/water (nano-polymer) with temperature-dependent viscosity. European Physical Journal Plus, 133(9), 1-12.
Scopus12 WoS122018 Mohammadian, M., Pourmehran, O., & Ju, P. (2018). An Iterative Approach to Obtaining the Nonlinear Frequency of a Conservative Oscillator with Strong Nonlinearities. International Applied Mechanics, 54(4), 470-479.
Scopus12 WoS92017 Pourmehran, O., Rahimi-Gorji, M., & Ganji, D. D. (2017). ANALYSIS OF NANOFLUID FLOW IN A POROUS MEDIA ROTATING SYSTEM BETWEEN TWO PERMEABLE SHEETS CONSIDERING THERMOPHORETIC AND BROWNIAN MOTION. THERMAL SCIENCE, 21(6B), 3063-3073.
WoS152017 Biglarian, M., Rahimi Gorji, M., Pourmehran, O., & Domairry, G. (2017). H<inf>2</inf>O based different nanofluids with unsteady condition and an external magnetic field on permeable channel heat transfer. International Journal of Hydrogen Energy, 42(34), 22005-22014.
Scopus60 WoS612017 Yousefi, M., Pourmehran, O., Gorji-Bandpy, M., Inthavong, K., Yeo, L., & Tu, J. (2017). CFD simulation of aerosol delivery to a human lung via surface acoustic wave nebulization. Biomechanics and Modeling in Mechanobiology, 16(6), 2035-2050.
Scopus58 WoS53 Europe PMC142017 Mosayebidorcheh, S., Rahimi-Gorji, M., Ganji, D. D., Moayebidorcheh, T., Pourmehran, O., & Biglarian, M. (2017). Transient thermal behavior of radial fins of rectangular, triangular and hyperbolic profiles with temperature-dependent properties using DTM-FDM. Journal of Central South University, 24(3), 675-682.
Scopus51 WoS442016 Pourmehran, O., Rahimi-Gorji, M., & Ganji, D. D. (2016). Heat transfer and flow analysis of nanofluid flow induced by a stretching sheet in the presence of an external magnetic field. Journal of the Taiwan Institute of Chemical Engineers, 65, 162-171.
Scopus90 WoS732016 Pourmehran, O., Gorji, T. B., & Gorji-Bandpy, M. (2016). Magnetic drug targeting through a realistic model of human tracheobronchial airways using computational fluid and particle dynamics. Biomechanics and Modeling in Mechanobiology, 15(5), 1355-1374.
Scopus93 WoS70 Europe PMC212016 Rahimi-Gorji, M., Pourmehran, O., Gorji-Bandpy, M., & Ganji, D. D. (2016). Unsteady squeezing nanofluid simulation and investigation of its effect on important heat transfer parameters in presence of magnetic field. Journal of the Taiwan Institute of Chemical Engineers, 67, 467-475.
Scopus103 WoS942015 Pourmehran, O., Rahimi-Gorji, M., Hatami, M., Sahebi, S. A. R., & Domairry, G. (2015). Numerical optimization of microchannel heat sink (MCHS) performance cooled by KKL based nanofluids in saturated porous medium. Journal of the Taiwan Institute of Chemical Engineers, 55, 49-68.
Scopus152 WoS1292015 Pourmehran, O., Rahimi-Gorji, M., Gorji-Bandpy, M., & Gorji, T. B. (2015). Simulation of magnetic drug targeting through tracheobronchial airways in the presence of an external non-uniform magnetic field using Lagrangian magnetic particle tracking. Journal of Magnetism and Magnetic Materials, 393, 380-393.
Scopus92 WoS752015 Rahimi-Gorji, M., Pourmehran, O., Gorji-Bandpy, M., & Gorji, T. B. (2015). CFD simulation of airflow behavior and particle transport and deposition in different breathing conditions through the realistic model of human airways. Journal of Molecular Liquids, 209, 121-133.
Scopus166 WoS1372015 Rahimi-Gorji, M., Pourmehran, O., Hatami, M., & Ganji, D. D. (2015). Statistical optimization of microchannel heat sink (MCHS) geometry cooled by different nanofluids using RSM analysis. European Physical Journal Plus, 130(2), 1-21.
Scopus173 WoS1502015 Pourmehran, O., Rahimi-Gorji, M., Gorji-Bandpy, M., & Baou, M. (2015). Comparison between the volumetric flow rate and pressure distribution for different kinds of sliding thrust bearing. Propulsion and Power Research, 4(2), 84-90.
Scopus26 WoS262015 Tavana, M., Pourmehran, O., Aghaei Khasraghei, A., Gorji-Bandpy, M., & Alipour Sangarab, J. (2015). Numerical analysis of fluid flow and heat transfer in microchannels with various internal fins. International Journal of Artificial Intelligence and Mechatronics, 3(4), 227-230. -
Conference Papers
Year Citation 2022 Pourmehran, O., Cazzolato, B., Tian, Z., & Arjomandi, M. (2022). Acoustic Behaviour of the Human Maxillary Sinus: The Importance of the Middle Meatus and the Ostium on Resonance Frequency Behaviour. In AIP (American Institute of Physics) Conference Proceedings Vol. 2425 (pp. 1-5). online: AIP.
DOI Scopus12020 Pourmehran, O., Arjomandi, M., Cazzolato, B., & Tian, Z. (2020). Effect of Particle Diameter and Density on Acoustic Drug Delivery to Maxillary Sinus – a Sensitivity Study. In Proceedings of the 22nd Australasian Fluid Mechanics Conference AFMC2020 (pp. 1-4). online: The University of Queensland.
DOI
| Grant Title | Scheme and Year | Chief Investigators | Amount Awarded |
|---|---|---|---|
| The AIRSPACE Trial: AntI-MRSA PhAge Cocktail treatment via Acoustic Enhanced Nebulisers |
NHMRC Medical Research Future Fund #2014977 (2022-2026) |
Wormald, Vreudge, Psaltis, Morales, Pourmehran, Cazzolato, Arjomandi, Louise, Schubert | $1,712,000 |
| Acoustic Drug Delivery for CRS Treatment |
Passe & Williams Foundation - Conjoint Grant (2022-2025) |
Wormald, Pourmehran | $375,000 |
| Adelaide Medical School Research Equipment Grants |
Equipment Grants (2024) |
Pourmehran | $5,000 |
Fluid Mechanics I
Fluid Mechanics II
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Current Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2024 Principal Supervisor A comprehensive Study of magnetic drug targeting in human maxillary sinuses for drug delivery applications Doctor of Philosophy Doctorate Full Time Mr Kavan Zarei 2024 Principal Supervisor A comprehensive numerical and experimental study of transport phenomena in nebulizer drug delivery targeting paranasal sinuses Doctor of Philosophy Doctorate Full Time Mr Alireza Meymivand 2024 Principal Supervisor Applying Computational Fluid Dynamics (CFD) to understand the flow behavior in patients with Empty Nose Syndrome (ENS) Doctor of Philosophy Doctorate Full Time Mr Jun Xiao -
Other Supervision Activities
Date Role Research Topic Location Program Supervision Type Student Load Student Name 2024 - ongoing Co-Supervisor Evaluating Nasal Irrigation Flow Dynamics and Eustachian Tube Involvement: A Computational Fluid Dynamics Approach The University of Adelaide - Honours - Syed Ahmed Luqman, Daniel Jungyun Kim, Danielle Zafiropoulos, 2023 - ongoing Co-Supervisor High-resolution image assessment of the mandibular canal morphology in CT images. The University of Adelaide Bachelor of Dental Surgery Honours Full Time Aaditya Mangla 2023 - ongoing Principal Supervisor Development of nebuliser device for clinical trial The University of Adelaide Research Assistance, and Internship Other Part Time Uri Hauben -
Mentoring
Date Topic Location Name 2023 - ongoing The effect of functional endoscopic sinus surgery on nasal obstruction using computational fluid dynamics The University of Adelaide Isabella Amy Burdon
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Committee Memberships
Date Role Committee Institution Country 2024 - ongoing Chair Mini-Oral 2 session at TQEH Research Expo The Basil Hetzel Institute for Translational Health Research (BHI) Australia 2024 - ongoing Board Member Organising Committee of The Queen Elizabeth Hospital Research Expo 2024 The Basil Hetzel Institute for Translational Health Research (BHI) Australia 2023 - 2023 Chair SESSION #2: CLINICAL APPLICATIONS IN THE NOSE & AIRWAY SCONA2023; 15th Asia Oceania ORL-HNS Congress Australia -
Memberships
Date Role Membership Country 2024 - ongoing Member European Society of Biomechanics (ESB) Switzerland 2022 - ongoing Member Passe and Williams Foundation Australia 2021 - ongoing Member Early- and Mid-Career Researchers, Australian Academy of Science Australia 2020 - ongoing Member Australasian Fluid Mechanics Society Australia 2018 - ongoing Member Acoustics Vibration and Control (AVC) Group Australia -
Editorial Boards
Date Role Editorial Board Name Institution Country 2023 - ongoing Editor Nano and Medical Materials Academic Publishing Pte Ltd Singapore 2023 - ongoing Board Member European Journal of Case Reports and Clinical Images European Journal of Case Reports United States 2023 - ongoing Associate Editor Frontiers in Medical Engineering Frontiers Switzerland 2023 - ongoing Associate Editor Frontiers in Mechanical Engineering Frontiers Switzerland 2021 - ongoing Editor Special Issue "Recent Advances on Acoustic, Ultrasonic, and Magnetic Drug Delivery" (IF 5.215) MDPI Multidisciplinary Digital Publishing Institute Switzerland 2019 - ongoing Board Member Journal of Nanosciences: Current Research Hilaris Publisher Belgium 2017 - ongoing Board Member SCIREA Journal of Mechanical Engineering Scientific Research Association (SCIREA) United States -
Event Participation
Date Event Name Event Type Institution Country 2023 - 2023 Medical Device Research Institute (MDRI) Showcase event Fair Flinders University Australia 2022 - 2022 ANFF-SA Microengineering School Workshop Australian National Fabrication Facility Australia 2018 - 2018 MATLAB Academic Conference in Adelaide Conference MathWorks - -
Presentation
Date Topic Presented at Institution Country 2023 - ongoing CFD simulation of nasal irrigation and nebulisation for drug delivery to post operative sinuses Basil Hetzel Institute for Translational Health Research (BHI) Central Adelaide Local Health Network, Adelaide, Australia Australia 2023 - 2023 Comparison of Squeeze Bottle and Nebuliser in Sinus Drug Delivery: A Computational Modelling SCONA2023 in conjunction with Asia Oceania ORL-HNS Congress 2023 Translational Research Institute, Brisbane, Australia Australia -
Review, Assessment, Editorial and Advice
Date Title Type Institution Country 2023 - ongoing AAPG Generic call - 2023 Grant Assessment French National Research Agency (ANR) AAPG 2023 France 2022 - 2022 PRACE 24th Call for Proposals for Project Access Grant Assessment Partnership for Advanced Computing in Europe (PRACE) Belgium
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