Grant-Funded Researcher (A)
Adelaide Medical School
Faculty of Health and Medical Sciences
Eligible to supervise Masters and PhD (as Co-Supervisor) - email supervisor to discuss availability.
Oveis Pourmehran began research in the field of targeted drug delivery during his master program (2013-2015), in which he developed several computational fluid dynamics (CFD) models to computationally simulate magnetic drug targeting to improve the efficiency of drug delivery to the human lungs.
In 2017, Oveis joined the University of Adelaide (Australia) as a PhD candidate and completed his PhD thesis titled "Understanding the flow behaviour in human maxillary sinuses for drug delivery applications" with the School of Mechanical Engineering in 2021. His Ph.D. program has contributed to the development of an advanced technique for drug delivery to the human sinuses using a tailored acoustic wave. In this research program, for the first time, he developed a high-fidelity direct computational aero-acoustic model to investigate the effect of the acoustic wave on drug delivery to the human maxillary sinuses, which shed new insight into the acoustic drug delivery technique. Also, his experiments showed that the acoustic drug delivery technique has the potential to increase drug delivery efficiency >45-fold when compared to the conventional nebulised drug delivery method.
Since June 2021, Oveis has joined the Department of Otolaryngology, Head and Neck Surgery, Adelaide Medical School, at the University of Adelaide as a postdoctoral research fellow, and established a Biomedical Engineering Research Node to develop novel drug delivery methods/devices to improve treatment efficiency in human upper airway diseases. Jointly with lead researchers and scientists from the ENT research group at the medical school and researchers at the school of mechanical engineering, he, as a chief investigator, has been awarded several research grants totaling>$2m (2022-2025), to develop cutting-edge techniques/devices for drug delivery to the upper airways and to the sinuses for CF and CRS treatment.
As a multi-disciplinary research team, the ENT surgery group, managed by Prof Peter-John Wormald, has recently established a Biomedical Engineering research node, mentored by Oveis Pourmehran, to develop novel drug delivery methods/devices for the improvement of the treatment efficiency in upper airway diseases.
The following research topics are available for PhD applicants, HDR, Honours, and 3rd Year students in 2022:
- Acoustic drug delivery to paranasal sinuses.
- Development of a mesh nebuliser for improvement of sinus drug delivery.
- Virtual endoscopic sinus surgery (ESS) followed by airflow analysis and particle tracking in the nasal cavity and paranasal sinuses.
- Magnetic & electric-charged particle (drug) delivery to human lung and paranasal sinuses.
The following techniques/skills are exploited to conduct these research projects: Computational fluid dynamics (CFD), particle tracking using DPM-CFD, finite element analysis (FEA), signal processing (acoustics), computer-aided design (CAD) modelling, CT-scan reconstruction (3D Slicer and other potential software), and cutting-edge 3D printing technology (e.g., FUSETEC).
Date Position Institution name 2021 - ongoing Postdoctoral Research Fellow The University of Adelaide 2017 - 2021 PhD candidate The University of Adelaide
Awards and Achievements
Date Type Title Institution Name Country Amount 2021 Award Dean's Commendation for Doctoral Thesis Excellence The University of Adelaide Australia 2020 Award ECMS High-Impact publication in the sector of "Health Solutions" The University of Adelaide Australia 2020 Award Frank Perry Travelling Scholarship in Engineering The University of Adelaide Australia 2017 Scholarship Beacon of Enlightenment PhD Scholarship The University of Adelaide Australia 2015 Award Distinguished Graduated Student National Elite Foundation Iran, Islamic Republic of
Date Institution name Country Title 2017 - 2021 The University of Adelaide Australia PhD 2013 - 2015 Babol Noshirvani University of Technology Iran M.Sc
Year Citation 2022 Pourmehran, O., Cazzolato, B., Tian, Z., & Arjomandi, M. (2022). The effect of inlet flow profile and nozzle diameter on drug delivery to the maxillary sinus. Biomechanics and Modeling in Mechanobiology, 21(3), 849-870.
2021 Pourmehran, O., Arjomandi, M., Cazzolato, B., Tian, Z., Vreugde, S., Javadiyan, S., . . . Wormald, P. -J. (2021). Acoustic drug delivery to the maxillary sinus.. Int J Pharm, 606, 1-15.
DOI Scopus3 WoS3 Europe PMC1
2021 Islam, M. S., Larpruenrudee, P., Saha, S. C., Pourmehran, O., Paul, A. R., Gemci, T., . . . Gu, Y. (2021). How severe acute respiratory syndrome coronavirus-2 aerosol propagates through the age-specific upper airways. Physics of Fluids, 33(8), 081911-1-081911-13.
DOI Scopus12 WoS12 Europe PMC1
2021 Taheri, M. H., Pourmehran, O., Sarafraz, M. M., Ahookhosh, K., Farnoud, A., & Cui, X. (2021). Effect of swirling flow and particle-release pattern on drug delivery to human tracheobronchial airways. Biomechanics and Modeling in Mechanobiology, 20(6), 2451-2469.
DOI Scopus5 WoS4 Europe PMC2
2020 Sarafraz, M. M., Pourmehran, O., Yang, B., Arjomandi, M., & Ellahi, R. (2020). Pool boiling heat transfer characteristics of iron oxide nano-suspension under constant magnetic field. International Journal of Thermal Sciences, 147, 106131.
DOI Scopus98 WoS97
2020 Ahookhosh, K., Pourmehran, O., Aminfar, H., Mohammadpourfard, M., Sarafraz, M. M., & Hamishehkar, H. (2020). Development of Human Respiratory Airway Models: A Review.. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 145, 1-22.
DOI Scopus26 WoS24 Europe PMC2
2020 Arya, H., Sarafraz, M. M., Pourmehran, O., & Arjomandi, M. (2020). Performance index improvement of a double-pipe cooler with MgO/water-ethylene glycol (50:50) nano-suspension. Propulsion and Power Research, 9(1), 75-86.
DOI Scopus4 WoS3
2020 Pourmehran, O., Cazzolato, B., Tian, Z., & Arjomandi, M. (2020). Acoustically-driven drug delivery to maxillary sinuses: aero-acoustic analysis. European Journal of Pharmaceutical Sciences, 151, 1-14.
DOI Scopus7 WoS7 Europe PMC2
2019 Arya, H., Sarafraz, M. M., Pourmehran, O., & Arjomandi, M. (2019). Heat transfer and pressure drop characteristics of MgO nanofluid in a double pipe heat exchanger. Heat and Mass Transfer, 55(6), 1769-1781.
DOI Scopus26 WoS19
2019 Sarafraz, M., Pourmehran, O., Yang, B., & Arjomandi, M. (2019). Assessment of the thermal performance of a thermosyphon heat pipe using zirconia-acetone nanofluids. Renewable Energy, 136, 884-895.
DOI Scopus87 WoS77
2019 Sarafraz, M., Yang, B., Pourmehran, O., Arjomandi, M., & Ghomashchi, R. (2019). Fluid and heat transfer characteristics of aqueous graphene nanoplatelet (GNP) nanofluid in a microchannel. International Communications in Heat and Mass Transfer, 107, 24-33.
DOI Scopus70 WoS64
2019 Sarafraz, M. M., Silakhori, M., Madani, S. A., Kiamahalleh, M. V., & Pourmehran, O. (2019). Thermal and hydraulic performance of a heat exchanger working with carbon-water nanofluid. Heat and Mass Transfer/Waerme- und Stoffuebertragung, 55(12), 3443-3453.
DOI Scopus6 WoS6
2019 Pourmehran, O., Arjomandi, M., Cazzolato, B., Ghanadi, F., & Tian, Z. (2019). The impact of geometrical parameters on acoustically driven drug delivery to maxillary sinuses.. Biomech Model Mechanobiol, 19(2), 557-575.
DOI Scopus10 WoS9 Europe PMC2
2018 Tabassum, R., Mehmood, R., Pourmehran, O., Akbar, N. S., & Gorji-Bandpy, M. (2018). Impact of viscosity variation on oblique flow of Cu–H2O nanofluid. Proceedings of the Institution of Mechanical Engineers, Part E: Journal of Process Mechanical Engineering, 232(5), 622-631.
DOI Scopus24 WoS19
2018 Mehmood, R., Tabassum, R., Pourmehran, O., & Ganji, D. D. (2018). Crosswise stream of hydrogen-oxide (H2O) through a porous media containing copper nanoparticles. International Journal of Hydrogen Energy, 43(15), 7562-7569.
DOI Scopus14 WoS14
2018 Pourmehran, O., Sarafraz, M., Rahimi-Gorji, M., & Ganji, D. (2018). Rheological behaviour of various metal-based nano-fluids between rotating discs: a new insight. Journal of the Taiwan Institute of Chemical Engineers, 88, 37-48.
DOI Scopus58 WoS55
2018 Sarafraz, M., Pourmehran, O., Nikkhah, V., & Arya, A. (2018). Pool boiling heat transfer to zinc oxide-ethylene glycol nano-suspension near the critical heat flux. Journal of Mechanical Science and Technology, 32(5), 2309-2315.
DOI Scopus9 WoS6
2018 Tabasum, R., Mehmood, R., & Pourmehran, O. (2018). Velocity slip in mixed convective oblique transport of titanium oxide/water (nano-polymer) with temperature-dependent viscosity. European Physical Journal Plus, 133(9), 1-12.
DOI Scopus11 WoS12
2018 Mohammadian, M., Pourmehran, O., & Ju, P. (2018). An Iterative Approach to Obtaining the Nonlinear Frequency of a Conservative Oscillator with Strong Nonlinearities. International Applied Mechanics, 54(4), 470-479.
2017 Pourmehran, O., Rahimi-Gorji, M., & Ganji, D. D. (2017). ANALYSIS OF NANOFLUID FLOW IN A POROUS MEDIA ROTATING SYSTEM BETWEEN TWO PERMEABLE SHEETS CONSIDERING THERMOPHORETIC AND BROWNIAN MOTION. THERMAL SCIENCE, 21(6), 3063-3073.
2017 Biglarian, M., Rahimi Gorji, M., Pourmehran, O., & Domairry, G. (2017). H<inf>2</inf>O based different nanofluids with unsteady condition and an external magnetic field on permeable channel heat transfer. International Journal of Hydrogen Energy, 42(34), 22005-22014.
DOI Scopus51 WoS56
2017 Yousefi, M., Pourmehran, O., Gorji-Bandpy, M., Inthavong, K., Yeo, L., & Tu, J. (2017). CFD simulation of aerosol delivery to a human lung via surface acoustic wave nebulization. Biomechanics and Modeling in Mechanobiology, 16(6), 2035-2050.
DOI Scopus51 WoS48 Europe PMC9
2017 Mosayebidorcheh, S., Rahimi-Gorji, M., Ganji, D. D., Moayebidorcheh, T., Pourmehran, O., & Biglarian, M. (2017). Transient thermal behavior of radial fins of rectangular, triangular and hyperbolic profiles with temperature-dependent properties using DTM-FDM. Journal of Central South University, 24(3), 675-682.
DOI Scopus43 WoS42
2016 Pourmehran, O., Rahimi-Gorji, M., & Ganji, D. D. (2016). Heat transfer and flow analysis of nanofluid flow induced by a stretching sheet in the presence of an external magnetic field. Journal of the Taiwan Institute of Chemical Engineers, 65, 162-171.
DOI Scopus74 WoS66
2016 Pourmehran, O., Gorji, T. B., & Gorji-Bandpy, M. (2016). Magnetic drug targeting through a realistic model of human tracheobronchial airways using computational fluid and particle dynamics. Biomechanics and Modeling in Mechanobiology, 15(5), 1355-1374.
DOI Scopus69 WoS59 Europe PMC13
2016 Rahimi-Gorji, M., Pourmehran, O., Gorji-Bandpy, M., & Ganji, D. D. (2016). Unsteady squeezing nanofluid simulation and investigation of its effect on important heat transfer parameters in presence of magnetic field. Journal of the Taiwan Institute of Chemical Engineers, 67, 467-475.
DOI Scopus90 WoS87
2015 Pourmehran, O., Rahimi-Gorji, M., Hatami, M., Sahebi, S. A. R., & Domairry, G. (2015). Numerical optimization of microchannel heat sink (MCHS) performance cooled by KKL based nanofluids in saturated porous medium. Journal of the Taiwan Institute of Chemical Engineers, 55, 49-68.
DOI Scopus133 WoS120
2015 Pourmehran, O., Rahimi-Gorji, M., Gorji-Bandpy, M., & Gorji, T. B. (2015). Simulation of magnetic drug targeting through tracheobronchial airways in the presence of an external non-uniform magnetic field using Lagrangian magnetic particle tracking. Journal of Magnetism and Magnetic Materials, 393, 380-393.
DOI Scopus77 WoS71
2015 Rahimi-Gorji, M., Pourmehran, O., Gorji-Bandpy, M., & Gorji, T. B. (2015). CFD simulation of airflow behavior and particle transport and deposition in different breathing conditions through the realistic model of human airways. Journal of Molecular Liquids, 209, 121-133.
DOI Scopus131 WoS121
2015 Rahimi-Gorji, M., Pourmehran, O., Hatami, M., & Ganji, D. D. (2015). Statistical optimization of microchannel heat sink (MCHS) geometry cooled by different nanofluids using RSM analysis. European Physical Journal Plus, 130(2), 1-21.
DOI Scopus153 WoS140
2015 Pourmehran, O., Rahimi-Gorji, M., Gorji-Bandpy, M., & Baou, M. (2015). Comparison between the volumetric flow rate and pressure distribution for different kinds of sliding thrust bearing. Propulsion and Power Research, 4(2), 84-90.
2015 Tavana, M., Pourmehran, O., Aghaei Khasraghei, A., Gorji-Bandpy, M., & Alipour Sangarab, J. (2015). Numerical analysis of fluid flow and heat transfer in microchannels with various internal fins. International Journal of Artificial Intelligence and Mechatronics, 3(4), 227-230.
Year Citation 2020 Pourmehran, O., Cazzolato, B., Tian, Z., & Arjomandi, M. (2020). Acoustic Behaviour of the Human Maxillary Sinus: The Importance of the Middle Meatus and the Ostium on Resonance Frequency Behaviour. In AIP (American Institute of Physics) Conference Proceedings Vol. 2425. online: AIP.
2020 Pourmehran, O., Arjomandi, M., Cazzolato, B., & Tian, Z. (2020). Effect of Particle Diameter and Density on Acoustic Drug Delivery to Maxillary Sinus – a Sensitivity Study. In Proceedings of the 22nd Australasian Fluid Mechanics Conference AFMC2020 (pp. 1-4). online: The University of Queensland.
2022-2025: NHMRC Medical Research Future Fund (#2014977), 'The AIRSPACE Trial: AntI-MRSA PhAge Cocktail treatment via Acoustic Enhanced Nebulisers', (CIs: Wormald, Vreudge, Psaltis, Morales, Pourmehran, Cazzolato, Arjomandi, Louise, Schubert). Role: Chief Investigator E ($1,712,000).
2022-2025: Passe & Williams Foundation - Conjoint Grant, 'Acoustic Drug Delivery for CRS Treatment', (CIs: Wormald, Pourmehran). Role: Chief Investigator B ($375,000).
Date Role Membership Country 2022 - ongoing Member Passe and Williams Foundation Australia 2021 - ongoing Member Early- and Mid-Career Researchers, Australian Academy of Science Australia 2020 - ongoing Member Australasian Fluid Mechanics Society Australia 2018 - ongoing Member Acoustics Vibration and Control (AVC) Group Australia
Date Role Editorial Board Name Institution Country 2021 - ongoing Editor Special Issue "Recent Advances on Acoustic, Ultrasonic, and Magnetic Drug Delivery" (IF 5.215) MDPI Multidisciplinary Digital Publishing Institute Switzerland
Review, Assessment, Editorial and Advice
Date Title Type Institution Country 2022 - 2022 PRACE 24th Call for Proposals for Project Access Grant Assessment Partnership for Advanced Computing in Europe (PRACE) Belgium
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