Nigel Farrow

Dr Nigel Farrow

University Postdoctoral Fellow

Adelaide Medical School

Faculty of Health and Medical Sciences

Eligible to supervise Masters and PhD (as Co-Supervisor) - email supervisor to discuss availability.


Dr Nigel Farrow completed his PhD at the University of Adelaide in 2015 and was awarded a Dean's Commendation for Doctoral Thesis Excellence for his PhD thesis titled "Cystic Fibrosis: The role of airway stem cells in sustained gene expression by lentiviral directed gene therapy. In 2015 Nigel was also awarded the Pride of Australia medal. Nigel’s research is focused on correcting the genetic cause of cystic fibrosis at a cellular level in the airways. To achieve this a modified virus is used as a transport mechanism to introduce a healthy copy of the cystic fibrosis gene into the airway cells. Not only is the gene inserted into the cell but we have chosen a virus that has the ability to insert the gene into the genome of the recipient allowing stable gene integration for the life of the cells.

The next step is that the cells have a life span so they are eventually lost and the procedure would have to be repeated. To combat the loss of the cells he is developing a way to target the adult stem cells that live in the airway and replace the cells as they die off as a natural process. By targeting the airway stem cells for inserting a healthy copy of the CF gene then they will pass on the healthy CF gene to their daughter cells. This has the potential of providing a means to prevent cystic fibrosis airway disease with a single treatment early in life that will last for the lifetime of the patient.

Nigel is also researching an alternative approach and has demonstrated that the airway stem cells can be removed from the lungs and treated with the viral vector to insert a gene. The cells can then be grown in the lab to expand the numbers before transplanting them back into a conditioned airway.

Nigel’s work has been accepted and published in the greater scientific community through peer reviewed scientific journal publications. Nigel has also been invited to present his work at conferences in Australia, New Zealand, the United Kingdom and the USA.

CI Channel 7 Children’s Research Foundation Grant 2019                      $34,625

AI Women’s and Children’s Hospital Foundation Grant 2019-20   1        $75,000

AI Women’s and Children’s Hospital Foundation Grant 2019-20   2        $75,000 

CI MS McLeod Postdoctoral Research Fellowship 2019-21                    $310,000

CI University of Pennsylvania, pilot grant program  2019                        $73,783            

CI Robinson Research Institute research travel award 2018                  $2,000.00

AI Women’s and Children’s Hospital Foundation Grant 2018-19            $75,240                                                                      

CI Cure 4 Cystic Fibrosis Foundation Grant 2018                                   $30,374                                                                                                            

CI Women’s and Children’s Hospital Foundation Grant 2017-18            $72,975                                                        

CI AMP tomorrow fund 2017 $25,000                                                                                                       

Robinson Research Institute research travel award 2017                       $850.00                                                                                                                                               

CI Cystic fibrosis South Australia research fund 2016                             $30,000                                                     

Robinson Research Institute international research travel award 2015  $2,200                                                      

Robinson Research Institute international research travel award 2014  $2,200

CI MS McLeod foundation PhD scholarship                                           $75,000                                                                                           

Cystic Fibrosis Australia PhD scholarship                                              $15,000                                                                                        

Robinson institute centre for stem cell research honours scholarship    $5,000                                             

Robinson institute centre for stem cell research summer scholarship    $2,000

  • Position: University Postdoctoral Fellow
  • Phone: 81619183
  • Email: nigel.farrow@adelaide.edu.au
  • Campus: Womens & Childrens Hospital
  • Building: WCH - Gilbert Building, floor G
  • Room: G6 027
  • Org Unit: Paediatrics and Reproductive Health

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