Senior Research Officer
Adelaide Medical School
Faculty of Health and Medical Sciences
Senior Research Officer and Clinical Trials Coordinator
Nicole is the Senior Research Officer and Clinical Research Coordinator for A/Professor Richard L Young
Intestinal Nutrient Sensing Group, Centre for Nutrition & Gastrointestinal Diseases, Lifelong Health Theme, South Australian Health & Medical Research Institute (SAHMRI)
Adelaide Medical School & NHMRC Centre of Research Excellence in Translating Nutritional Science to Good Health, The University of Adelaide
Nicole is the Clinical Trials Coordinator for PARC Clinical Research Group, located in Level 4C, Royal Adelaide Hospital
Clinical Trials currently underway (from June 2021) ...
Unexplained Anaemia of Aging Trial with PARC Clincial Research Group
The purpose of this study is to test an investigational drug, BGE-117 for unexplained anaemia of aging.
If you are aged 65 years and older, feeling fatigued, weak, or short of breath? This may not just be “normal aging”; instead, you may have symptoms of unexplained anemia
If additional testing reveals you have unexplained anaemia and you agree to participate in this study, you will be randomized (assigned by chance, like the flip of a coin) to receive either the test drug or a placebo. Neither you, your doctor, nor the doctor’s staff will know whether you are getting the test drug or placebo. You will take the study medication once a day for up to 12 weeks.
The study will take place over 22 weeks. You will have 16 visits to the study clinic. Each study visit will last approximately 1-2 hours, depending on what tests are required at the visit.
At the visits we will be asking you about your medical history, including any illnesses and medicines you are taking or have taken. We will conduct a physical exam, including measurements of your heart rate, blood pressure, height & weight. We will draw blood for lab tests, take urine and a stool sample for testing. We will also be conducting physical function tests, which include walking, balance, standing and hand grip strength. Other tests we will conduct include and ECG to record the electrical activity of your heart, vascular doppler ultrasound to measure the amount of blood flowing through your blood vessels, an eye exam and completing questionnaires about your overall health, quality of life and experiences of fatigue.
You will be reimbursed for your time and any reasonable travel, parking, meals and other expenses associated with the research project visit.
The research ethics committee of RAH have reviewed this study in detail and have approved its conduct.
If you would like to be considered for involvement in the Unexplained Anaemia of Aging study, we have a few questions we would like to ask you to determine your suitability to attend a Pre-Screening appointment. Please click here for the questionnaire.
Sweet Taste Diabetes Research Trials with the Intestinal Nutrient Sensing Group
Please contact Nicole 8128 8463 or firstname.lastname@example.org if you are interested in volunteering your time for clinical research trials.
Date Institution name Country Title 1996 - 1997 University of Adelaide Australia Bachelor of Science (Hons) 1992 - 1996 University of Adelaide Australia Bachelor of Science
Date Title Institution name Country — Certificate IV in Veterinary Nursing TAFE SA - Gilles Plains Campus Australia
Research InterestsAnimal Cell and Molecular Biology Animal Nutrition Biochemistry & Molecular Biology Biochemistry and Cell Biology Biological Sciences Cell Biology Clinical Sciences Clinical Trials Medical and Health Sciences Medical Bacteriology Medical Biochemistry and Metabolomics Microscopy Nutrition and Metabolic Health Translational Health Outcomes
Year Citation 2013 Hughes, P. A., Harrington, A. M., Castro, J., Isaacs, N. J., Moretta, M., Hicks, G. A., . . . Brierley, S. M. (2013). Increased Efficacy of the Peripherally-Restricted Selective Kappa-Opioid Receptor Agonist, Asimadoline, in Chronic Visceral Hypersensitivity. In GASTROENTEROLOGY Vol. 144 (pp. S934-S935). Orlando, FL: W B SAUNDERS CO-ELSEVIER INC. 2012 Hughes, P. A., Isaacs, N. J., Moretta, M., Hicks, G. A., Urso, D. M., Blackshaw, L. A., & Brierley, S. M. (2012). Identification of Kappa Opioid Receptors on Colonic Sensory Nerves and Their Up-Regulation in a Mouse Model of Chronic Visceral Hypersensitivity. In GASTROENTEROLOGY Vol. 142 (pp. S702). San Diego, CA: W B SAUNDERS CO-ELSEVIER INC. 2012 Harrington, A. M., Brierley, S. M., Castro, J., Isaacs, N. J., & Blackshaw, L. A. (2012). Characterization of Dorsal Horn Neurons Activated by Noxious Colorectal Distension in Health and Chronic Visceral Hypersensitivity. In GASTROENTEROLOGY Vol. 142 (pp. S699). San Diego, CA: W B SAUNDERS CO-ELSEVIER INC. 2009 Harrington, A., Hughes, P., Martin, C., Isaacs, N., Brierley, S., & Blackshaw, L. (2009). Localisation and function of transient receptor potential ion channel melastatin subtype 8 (TRPM8) in mouse colonic primary afferent nerve fibers. In Autonomic neuroscience Vol. 149 (pp. 29). United States: Elsevier B.V..
2002 Young, R. L., Cooper, N. J., & Blackshaw, L. A. (2002). Neurochemical coding of gastric vago-vagal pathways in the ferret. In JOURNAL OF PHYSIOLOGY-LONDON Vol. 543 (pp. 5P). UNIV LIVERPOOL, LIVERPOOL, ENGLAND: CAMBRIDGE UNIV PRESS.
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