Nhi Hin
School of Biological Sciences
Faculty of Sciences
Nhi Hin is a Bioinformatician and Computational Biologist in the South Australian Genomics Centre (SAGC) situated in SAHMRI. Her current research interests include transcriptomics, single-cell RNA-seq analysis, omics data integration, and systems biology analysis.
Nhi Hin completed her PhD at the University of Adelaide's Alzheimer's Disease Genetics Laboratory and former Bioinformatics Hub in 2020. Her doctoral studies involved using transcriptomic analysis to elucidate incipient stages of Alzheimer's disease at the molecular level. Her presentations relating to this research have been recognised nationally with five awards from bioinformatics and biomedical conferences. A summary of the research completed during her studies is provided in the video presentation below.
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Appointments
Date Position Institution name 2020 Bioinformatician South Australian Genomics Centre (SAGC) -
Awards and Achievements
Date Type Title Institution Name Country Amount 2020 Award Dean's Commendation for Doctoral Thesis Excellence The University of Adelaide Australia — 2019 Award Oral Presentation Prize (1st Place), out of 15 speakers COMBINE/ABACBS Australia — 2019 Award Best Poster Award, out of 35 entrants Australian Mathematical Sciences Institute (AMSI) Australia — 2019 Scholarship CHOOSEMATHS Travel Grant Winner Australian Mathematical Sciences Institute (AMSI) Australia — 2019 Award Best Student Presentation Award, out of 50 speakers Australia-Japan Neurodegenerative Disease Symposium Australia — 2018 Achievement Upgrade to PhD from MPhil The University of Adelaide Australia — 2017 Scholarship Master of Philosophy Scholarship (no honours) The University of Adelaide Australia — 2017 Award Oral Presentation Award (3rd Prize), out of 15 speakers COMBINE/ABACBS Australia — 2017 Award Best Poster Award, out of 36 entrants Model Organisms in Human Health Australia (MOHHA) conference Australia — 2016 Scholarship Summer Research Scholarship Placement (Genetics) The University of Adelaide Australia — 2016 Award Outstanding Academic Award The University of Adelaide Australia — 2015 Award Outstanding Academic Award The University of Adelaide Australia — 2015 Scholarship Summer Research Scholarship Placement (Chemistry) The University of Adelaide Australia — 2014 Award Outstanding Academic Award The University of Adelaide Australia — -
Education
Date Institution name Country Title 2017 - 2020 The University of Adelaide Australia Doctor of Philosophy 2014 - 2016 The University of Adelaide Australia Bachelor of Science (Advanced) -
Research Interests
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Journals
Year Citation 2020 Hin, N., Newman, M., Kaslin, J., Douek, A. M., Lumsden, A., Moussavi Nik, S. H., . . . Lardelli, M. (2020). Accelerated brain aging towards transcriptional inversion in a zebrafish model of the K115fs mutation of human PSEN2. PloS one, 15(1), e0227258.
Scopus2 WoS2 Europe PMC12020 Hin, N., Newman, M., Pederson, S., & Lardelli, M. (2020). Iron Responsive Element (IRE)-mediated responses to iron dyshomeostasis in Alzheimer’s disease.
2020 Newman, M., Nik, H. M., Sutherland, G. T., Hin, N., Kim, W. S., Halliday, G. M., . . . Lardelli, M. (2020). Accelerated loss of hypoxia response in zebrafish with familial Alzheimer's disease-like mutation of Presenilin 1.. Hum Mol Genet, 29(14), 2379-2394.
Scopus1 Europe PMC12020 Breen, J., McAninch, D., Jankovic-Karasoulos, T., McCullough, D., Smith, M., Bogias, K. J., . . . Roberts, C. (2020). Temporal placental genome wide expression profiles reflect three phases of utero-placental blood flow during early to mid human gestation.
2019 Newman, M., Hin, N., Pederson, S., & Lardelli, M. (2019). A familial Alzheimer's disease-like mutation in the zebrafish presenilin 1 gene affects brain energy production.
2019 Newman, M., Hin, N., Pederson, S., & Lardelli, M. (2019). Brain transcriptome analysis of a familial Alzheimer's disease-like mutation in the zebrafish presenilin 1 gene implies effects on energy production. Molecular Brain, 12(1), 1-5.
Scopus7 WoS7 Europe PMC32018 Hin, N., Newman, M., Kaslin, J., Douek, A. M., Lumsden, A., Zhou, X., . . . Lardelli, M. (2018). Accelerated brain aging towards transcriptional inversion in a zebrafish model of familial Alzheimer's disease. BioRxiv, OnlinePubl.
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Figures
Year Citation — Newman, M. (n.d.). Gene editing in zebrafish to produce the psen1 K97fs mutation.
| Date | Project | Investigators | Funding Body | Amount |
|---|---|---|---|---|
| Dec 2019 | FND000377: AMSI Choose Maths Grant (AMSI-CMG) | Nhi Hin | Australian Mathematical Sciences Institute | $980 |
| Date | Course Title | Institution | URL |
|---|---|---|---|
| October 2019 | Spring Into Bioinformatics | The University of Adelaide | https://www.thewaite.org/spring-into-bioinformatics-training-event/ |
| April 2019 | Introduction to NGS | The University of Adelaide | https://uofabioinformaticshub.github.io/Intro-NGS-fib/ |
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Committee Memberships
Date Role Committee Institution Country 2018 - 2018 Advisory Board Member COMBINE Executive Committee COMBINE Australia Australia 2017 - ongoing Member Australian Bioinformatics and Computational Biology Society Australian Bioinformatics and Computational Biology Society Australia -
Presentation
Date Topic Presented at Institution Country 2019 - 2019 RNA-seq analysis of a zebrafish model of Alzheimer’s disease reveals the importance of iron homeostasis COMBINE and ABACBS 2019 The University of Sydney Australia 2019 - 2019 Iron Enriched AMSI BioInfoSummer The University of Sydney Australia 2019 - ongoing Computational Analysis Reveals an Early Brain Iron Deficiency Response in a Zebrafish Mutation Model of Familial Alzheimer’s Disease Back to Basics: Understanding the Molecular Basis of Alzheimer’s Disease workshop The University of Sydney Australia 2019 - ongoing Iron deficiency with aging, hypoxia, and a familial Alzheimer’s disease-like mutation Alzheimer’s Association Satellite Symposium The University of Sydney Australia 2019 - ongoing Bioinformatic analysis of familial Alzheimer’s disease-like zebrafish Australia-Japan Neurodegenerative Disease Symposium The University of Adelaide Australia 2017 - ongoing Diving into Alzheimer’s Disease with Transcriptome Analysis of a Zebrafish Model COMBINE The University of Adelaide Australia 2017 - ongoing RNA-seq analysis of aging and Alzheimer’s disease in a zebrafish model — Model Organisms for Human Health Australia (MOHHA) conference Australia
Connect With Me
External Profiles
