Dr Neville Gully
Assistant Dean Learning and Teaching
Adelaide Dental School
Faculty of Health and Medical Sciences
Associate Professor Neville Gully
Assistant Dean Learning and Teaching, Adelaide Dental School.
Associate Professor of Oral Microbiology, University of Adelaide.
Areas of Research: Oral Microbiology, Human Oral Microbiome, Biofilms.
Research Collaborators:
Prof Alan Cooper, Head Centre Ancient DNA, University of Adelaide
Prof Mark Bartold, Director, Colgate Australian Clinical Dental Research Centre
Prof Grant Townsend, School of Dentistry, University of Adelaide
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Appointments
Date Position Institution name 2018 - ongoing Assistant Dean Learning and Teaching University of Adelaide, Adelaide 2012 - ongoing Associate Professor University of Adelaide 2010 - 2017 Assistant Dean Graduate Studies University of Adelaide 2007 - 2012 Senior Lecturer University of Adelaide 1993 - 2002 Lecturer University of Adelaide 1993 - 2002 Senior Research Officer University of Adelaide 1991 - 1992 Research Officer University of Adelaide 1979 - 1990 Technical /Sr. Technical Officer University of Adelaide -
Education
Date Institution name Country Title 2000 University of Adelaide Australia Doctor of Philosophy 1977 University of Adelaide Australia Bachelor of Science Honours 1976 University of Adelaide Australia Bachelor of Science -
Research Interests
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Journals
Year Citation 2020 Gatej, S. M., Bright, R., Weyrich, L. S., Marino, V., Christophersen, C. T., Gibson, R. J., . . . Bartold, P. M. (2020). Probiotic Lactobacillus Rhamnosus GG Protects Against P. Gingivalis And F. Nucleatum Gut Dysbiosis.. Journal of the International Academy of Periodontology, 22(2), 18-27.
Europe PMC52018 Gatej, S., Marino, V., Bright, R., Fitzsimmons, T., Gully, N., Zilm, P., . . . Bartold, P. (2018). Probiotic Lactobacillus rhamnosus GG prevents alveolar bone loss in a mouse model of experimental periodontitis. Journal of Clinical Periodontology, 45(2), 204-212.
Scopus45 WoS42 Europe PMC192017 Gatej, S., Gully, N., Gibson, R., & Bartold, P. M. (2017). Probiotics and Periodontitis - A Literature Review.. Journal of the International Academy of Periodontology, 19(2), 42-50.
Europe PMC52017 Weyrich, L., Duchene, S., Soubrier, J., Arriola, L., Llamas, B., Breen, J., . . . Cooper, A. (2017). Neanderthal behaviour, diet, and disease inferred from ancient DNA in dental calculus. Nature, 544(7650), 357-361.
Scopus241 WoS226 Europe PMC1072014 Gully, N., Bright, R., Marino, V., Marchant, C., Cantley, M., Haynes, D., . . . Bartold, M. (2014). Porphyromonas gingivalis peptidylarginine deiminase, a key contributor in the pathogenesis of experimental periodontal disease and experimental arthritis. PLoS One, 9(6), e100838-1-e100838-12.
Scopus72 WoS68 Europe PMC522013 Abdullah, S., Farmer, E., Spargo, L., Logan, R., & Gully, N. (2013). Porphyromonas gingivalis peptidylarginine deiminase substrate specificity. Anaerobe, 23, 102-108.
Scopus39 WoS35 Europe PMC252012 Seet, A., Zilm, P., Gully, N., & Cathro, P. (2012). Qualitative comparison of sonic or laser energisation of 4% sodium hypochlorite on an Enterococcus faecalis biofilm grown in vitro. Australian Endodontic Journal, 38(3), 100-106.
Scopus20 WoS17 Europe PMC102012 Chew, J., Zilm, P., Fuss, J., & Gully, N. (2012). A proteomic investigation of Fusobacterium nucleatum alkaline-induced biofilms. BMC Microbiology, 12(1), 1-14.
Scopus16 WoS25 Europe PMC192009 Knight, G., McIntyre, J., Craig, G., Mulyani., & Zilm, P. (2009). Inability to form a biofilm of Streptococcus mutans on silver fluoride- and potassium iodide-treated demineralized dentin. Quintessence International, 40(2), 155-161.
Scopus61 WoS50 Europe PMC282009 Townsend, G., Hughes, T., Mihailidis, S., Bockmann, M., Richards, L., Gully, N., . . . Seow, K. (2009). Primary tooth emergence in Australian singletons and twins. HOMO-JOURNAL OF COMPARATIVE HUMAN BIOLOGY, 60(3), 289-290.
2007 Hughes, T., Bockmann, M., Seow, W., Gotjamanos, T., Gully, N., Richards, L., & Townsend, G. (2007). Strong genetic control of emergence of human primary incisors. Journal of Dental Research, 86(12), 1160-1165.
Scopus56 WoS55 Europe PMC312007 Knight, G., McIntyre, J., Craig, G., Mulyani., Zilm, P., & Gully, N. (2007). An in vitro investigation of marginal dentine caries abutting composite resin and glass ionomer cement restorations. Australian Dental Journal, 52(3), 187-192.
Scopus17 WoS16 Europe PMC82007 Knight, G., McIntyre, J., Craig, G., Mulyani., Zilm, P., & Gully, N. (2007). Differences between normal and demineralized dentine pretreated with silver fluoride and potassium iodide after an in vitro challenge by Streptococcus mutans. Australian Dental Journal, 52(1), 16-21.
Scopus50 WoS38 Europe PMC262007 Zilm, P., Bagley, C., Rogers, A., Milne, I., & Gully, N. (2007). The proteomic profile of Fusobacterium nucleatum is regulated by growth pH. Microbiology, 153 Part 1(1), 148-159.
Scopus17 WoS18 Europe PMC132006 Townsend, G., Richards, L., Brearley-Messer, L., Hughes, T., Pinkerton, S., Seow, K., . . . Bockmann, M. (2006). Genetic and environmental influences on dentofacial structures and oral health: Studies of Australian twins and their families. Twin Research and Human Genetics, 9(6), 727-732.
Scopus24 WoS21 Europe PMC172005 Knight, G., McIntyre, J., Craig, G., Mulyani., Zilm, P., & Gully, N. (2005). An in vitro model to measure the effect of a silver fluoride and potassium iodide treatment on the permeability of demineralized dentine to Streptococcus mutans. Australian Dental Journal, 50(4), 242-245.
Scopus54 WoS47 Europe PMC192003 Zilm, P., Gully, N., & Rogers, A. (2003). Changes in growth and polyglucose synthesis in response to fructose metabolism by Fusobacterium nucleatum grown in continuous culture. Oral Microbiology and Immunology, 18(4), 260-262.
Scopus5 WoS4 Europe PMC22002 Zilm, P., Gully, N., & Rogers, A. (2002). Growth pH and transient increases in amino acid availability influence polyglucose synthesis by Fusobacterium nucleatum grown in continuous culture. FEMS Microbiology Letters, 215(2), 203-208.
Scopus12 WoS11 Europe PMC42001 Gully, N., & Rogers, A. (2001). The characterization of a (nutritionally important) proline iminopeptidase from Eikenella corrodens. Oral Microbiology and Immunology, 16(6), 370-375.
Scopus5 WoS5 Europe PMC31999 Rogers, A. H., & Gully, N. J. (1999). Tea tree oil as a potential antimicrobial agent in mouthrinses.. JOURNAL OF DENTAL RESEARCH, 78(5), 949.
WoS11998 Rogers, A., Gunadi, A., Gully, N., & Zilm, P. (1998). An aminopeptidase nutritionally important to Fusobacterium nucleatum. Microbiology, 144(7), 1807-1813.
Scopus14 WoS12 Europe PMC71998 Rogers, A., Chen, J., Zilm, P., & Gully, N. (1998). The behavior of Fusiobacterium nucleatum chemostat-grown in glucose- and amino acid -based chemically defined media. Anaerobe, 4(2), 111-116.
Scopus19 WoS20 Europe PMC171997 Rogers, A. H., Zilm, P. S., Gully, N. J., & Gunadi, A. (1997). The isolation and purification of an aminopeptidase from Fusobacterium nucleatum.. JOURNAL OF DENTAL RESEARCH, 76(5), 946. 1997 Gully, N. J., & Rogers, A. H. (1997). Energy production and proline-aminopeptidase activity in Eikenella corrodans.. JOURNAL OF DENTAL RESEARCH, 76(5), 946. 1996 Gully, N., & Rogers, A. (1996). Energy Production and Peptidase Activity in Eikenella Corrodens. FEMS Microbiology Letters, 139(2-3), 209-213.
Scopus8 WoS7 Europe PMC51995 Gully, N., & Rogers, A. (1995). Some observations on the nutritional requirements of Eikenella corrodens ATCC 23834T grown in continuous culture. Oral Microbiology and Immunology, 10(2), 115-118.
Scopus4 WoS8 Europe PMC81995 GULLY, N. J., & ROGERS, A. H. (1995). ENERGY-PRODUCTION BY EIKENELLA-CORRODENS GROWN IN CONTINUOUS-CULTURE. JOURNAL OF DENTAL RESEARCH, 74(3), 766. 1992 Rogers, A. H., Gully, N. J., Pfennig, A. L., & Zilm, P. S. (1992). The breakdown and utilization of peptides by strains of Fusobacterium nucleatum. Oral Microbiology and Immunology, 7(5), 299-303.
Scopus18 WoS20 Europe PMC191991 Rogers, A. H., Zilm, P. S., Gully, N. J., Pfennig, A. L., & Marsh, P. D. (1991). Aspects of the growth and metabolism of Fusobacterium nucleatum ATCC 10953 in continuous culture. Oral Microbiology and Immunology, 6(4), 250-255.
Scopus36 WoS36 Europe PMC271991 Bartold, P. M., Gully, N. J., Zilm, P. S., & Rogers, A. H. (1991). Identification of components in Fusobacterium nucleatum chemostat‐culture supernatants that are potent inhibitors of human gingival fibroblast proliferation. Journal of Periodontal Research, 26(4), 314-322.
Scopus34 WoS36 Europe PMC281991 Rogers, A. H., Pfennig, A. L., Gully, N. J., & Zilm, P. S. (1991). Factors affecting peptide catabolism by oral streptococci. Oral Microbiology and Immunology, 6(2), 72-75.
Scopus6 WoS8 Europe PMC61990 Rogers, A. H., Zilm, P. S., Pfennig, A. L., & Gully, N. J. (1990). Some aspects of protease production by a strain of Streptococcus sanguis. Oral Microbiology and Immunology, 5(2), 72-76.
Scopus14 WoS11 Europe PMC121990 Rogers, A. H., Zilm, P. S., Gully, N. J., & Pfennig, A. L. (1990). Some aspects of arginine assimilation in a strain of Streptococcus sanguis. Current Microbiology, 20(1), 19-22.
Scopus2 WoS11989 ROGERS, A. H., ZILM, P. S., GULLY, N. J., & PFENNIG, A. L. (1989). THE CATABOLISM OF ARGININE-CONTAINING PEPTIDES BY STREPTOCOCCUS-SANGUIS. JOURNAL OF DENTAL RESEARCH, 68, 1686-1687.
WoS11989 ZILM, P. S., ROGERS, A. H., GULLY, N. J., & PFENNIG, A. L. (1989). THE CHARACTERIZATION OF ARGININE UPTAKE BY STREPTOCOCCUS-SANGUIS. JOURNAL OF DENTAL RESEARCH, 68(4), 552. 1989 ROGERS, A. H., ZILM, P. S., PFENNIG, A. L., & GULLY, N. J. (1989). GROWTH OF STREPTOCOCCUS-SANGUIS ON CASEIN AND ITS ALPHA-S1 FRACTION. JOURNAL OF DENTAL RESEARCH, 68(4), 552. 1988 Rogers, A. H., Zilm, P. S., Gully, N. J., & Pfennig, A. L. (1988). Response of a Streptococcus sanguis strain to arginine-containing peptides. Infection and Immunity, 56(3), 687-692.
Scopus23 WoS22 Europe PMC201988 Rogers, A. H., Zilm, P. S., Gully, N. J., & Pfennig, A. L. (1988). The response of a strain of Streptococcus sanguis to arginine-containing peptides. Infection and Immunity, 56(3), 687-692. 1987 ROGERS, A. H., ZILM, P. S., & GULLY, N. J. (1987). THE RESPONSE TO L-SORBOSE OF ORAL STREPTOCOCCI GROWN IN A CHEMOSTAT. JOURNAL OF DENTAL RESEARCH, 66(4), 826. 1987 Rogers, A. H., Zilm, P. S., & Gully, N. J. (1987). Response to L-sorbose of oral streptococci grown in continuous culture. Caries Research, 21(3), 215-221.
Scopus1 Europe PMC11987 Rogers, A., Zilm, P., Gully, N., & Pfennig, A. (1987). Chlorhexidine affects arginine metabolism as well as glycolysis in a strain of Streptococcus sanguis. Oral Microbiology and Immunology, 2(4), 178-182.
Scopus14 Europe PMC111987 Rogers, A. H., Zilm, P. S., & Gully, N. J. (1987). Influence of arginine on the coexistence of Streptococcus mutans and S. milleri in glucose-limited mixed continuous culture. Microbial Ecology, 14(3), 193-202.
Scopus16 WoS15 Europe PMC131986 Rogers, A. H., Zilm, P. S., & Gully, N. J. (1986). The utilisation of arginine by oral streptococci grown glucose-limited in a chemostat. FEMS Microbiology Letters, 37(1), 9-13.
Scopus19 WoS211986 ROGERS, A. H., ZILM, P. S., MARSCHALL, R. L., & GULLY, N. J. (1986). ARGININE MODULATION OF THE GROWTH OF ORAL STREPTOCOCCI IN MIXED CONTINUOUS CULTURE. JOURNAL OF DENTAL RESEARCH, 65(4), 476. -
Conference Papers
Year Citation 1991 Rogers, A. H., Pilowsky, K. A., Zilm, P. S., & Gully, N. J. (1991). Effects of pulsing with xylitol on mixed continuous cultures of oral streptococci. In Australian Dental Journal Vol. 36 (pp. 231-235). Australia: AUSTRALIAN DENTAL ASSN INC.
Scopus22 WoS15 Europe PMC13 -
Conference Items
Year Citation 1998 Irani, D. M., Pierce, A. M., Gully, N. J., Haynes, D. R., & Wilson, D. F. (1998). Eikenella corrodens surface associated material stimulates osteolytic cytokines.. Poster session presented at the meeting of JOURNAL OF DENTAL RESEARCH. AMER ASSOC DENTAL RESEARCH. 1998 Irani, D. M., Pierce, A. M., Haynes, D. R., Gully, N. J., & Wilson, D. F. (1998). Eikenella corrodens surface associated material stimulates osteolytic cytokines.. Poster session presented at the meeting of JOURNAL OF DENTAL RESEARCH. SAGE PUBLICATIONS INC. 1989 GULLY, N. J., ROGERS, A. H., ZILM, P. S., & PFENNIG, A. L. (1989). THE CATABOLISM OF ARGININE-CONTAINING PEPTIDES BY STREPTOCOCCUS-SANGUIS. Poster session presented at the meeting of JOURNAL OF DENTAL RESEARCH. AMER ASSOC DENTAL RESEARCH.
Research Grants Since Appointment
| 2003 | Gully, Haynes, Rogers and Pierce. | ADRF 2003 Isolation of the osteoclastogenic factor from Eikenella corrodens surface associated material. | |
| 2002 - 2005 | Rogers, Gully and Brennan | NH&MRC 2002-05 Analysis of the effectiveness of a simple, inexpensive, saliva-based caries-risk test. | |
| 2003 | Zilm, Rogers and Gully. | ADRF 2003 The role of intracellular polysaccharide production in biofilm formation by Fusobacterium nucleatum. | |
| 2004 | Gully, Haynes, Rogers and Zilm. | ADRF 2004 Identification of the osteoclastogenic factor from Eikenella corrodens surface associated material. | |
| 2004 | Zilm, and Gully | ADRF 2004 The investigation and characterisation of the co-aggregation of Fusobacterium nucleatum grown in continuous culture. | |
| 2004 | Gully, Zilm and Clanachan. | ADRF 2004 Studies on growth and metabolism of Peptostreptococcus micros. | |
| 2004 - 2006 | Haynes, Bartold, Findlay and Gully | NH&MRC 2004-2006 Regulation of bone resorption in periodontal disease. | |
| 2005 | Gully and Zilm | ADRF 2005 Further studies on growth and metabolism of Peptostreptococcus micros | |
| 2005 | Mahajani, Zilm and Gully | ADRF 2005 Examination of the efficiency in removing bacterial contamination from Dental unit water lines using current treatment protocols. | $2,000 |
| 2004 - 2005 | Gully | Faculty of Health Science Research Establishment Grant 2004-05 An investigation of Biofilms | |
| 2005 - 2007 | Townsend, Seow, Gotjamanos, Hughes, Gully and Richards. | NH&MRC 2005-07 Tooth Emergence and Oral Streptococci colonisation: a Longitudinal study of Australian Twins | |
| 2006 | Zilm and Gully | ADRF The identification of proteins whose expression is altered by growth pH in Fusobacterium nucleatum. | |
| 2006 | Bartold, Haynes, Townsend, Slade, Gully, Rogers, Zilm Foster, Gabriel, Ong, Colier and Gronthos | NH&MRC Equipment Grant | |
| 2006 - 2007 | Gully and Zilm | ADRF A proteomic assessment of environmental pH on Fusobacterium nucleatum biofims. | |
| 2007 | Hughes, Bockmann, Townsend and Gully. | A host pathogen liability model for mutans streptococci virulence. School of Dentistry internal | |
| 2007 | Zilm and Gully | ADRF The expression of cell envelope proteins by Fusobacterium nucleatum in response to growth pH. | |
| 2007 | Townsend, Seow, Gotjamanos, Hughes, Gully and Richards. | ADRF The genetic basis of human tooth emergence-a twin study. | |
| 2008 | Gully, Zilm and Chew. | A proteomic identification of cell envelope proteins associated with biofilm formation by Fusobacterium nucleatum. ADRF 2008 | |
| 2008 | Gully, Zilm and Chew. | An identification of the key regulatory enzymes involved in intracellular polyglucose metabolism by Fusobacterium nucleatum biofilms. ADRF 2008 | |
| 2009 | Seet, Cathro, Zilm, McNamara and Gully. | An in-vitro evaluation of the effectiveness of endodontic irritants, with and without ultrasonic activation, in the eradication of Enterococcus faecalis biofilm. ADRF 2009 | |
| 2009 | Farmer and Gully. | The role of Porphyromonas gingivalis derived peptidylarginine deiminase (PAD) in the citrullination of -enolase as a common link in the pathogenesis periodontal disease and rheumatoid arthritis. ADRF 2009 | |
| 2009 | Chew, Gully and Zilm. | The effects of environmental redox potential (Eh) and pH on Fusobacterium nucleatum and Porphyromonas gingivalis co-cultured biofilms. ADRF 2009 | |
| 2009 | McNamara, Zilm and Gully. | Identification and quantitation of periodontal pathogens by real-time polymerase chain reaction. ADRF 2009 | |
| 2010 | Gully, Butler, Farmer and Marino. | The contribution of Porphyromonas gingivalis peptidyl arginine deiminase to the pathogenesis of rheumatoid arthritis. ADRF 2010 | |
| 2010 | Cathro, Zilm and Gully. | Proteomic analysis of cell surface proteins by Enterococcus faecalis in response to stress conditions. ADRF 2010 | |
| 2010 | Stenhouse, Cathro, Zilm and Gully. | The investigation of an Enterococcus faecalis biofilm grown on dentine and its resistance to alkaline pH ADRF 2010 | |
| 2010 | Chew, Zilm and Gully. | The role of S-Layer protein in biofilm formation by Fusobacterium nucleatum in response to high growth pH. ADRF 2010 | |
| 2010 | Chew, Gully, Zilm and Fuss. | Validation of key regulated proteins identified by proteomic analysis in F. nucleatum biofilms ADRF 2010 | |
| 2011 | Cooper, Kaidonis, Townsend, Gully, Bartold, Dobney, Higham, Richards and Lalueza-Fox. | A powerful new genetic view of the recent evolutionary history of humans and their diseases ARC 2011 | |
| 2015 | Gatej, Bartold and Gully. | Effect of probiotic treatment in an experimental model of periodontitis. ADRF 2015 |
| Program Coordination | |
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| Doctor of Clinical Dentistry | 2010-present |
| BSciDent(Hons) | 2014 - present |
| Year Coordination | |
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| 2nd Year Bachelor of Dental Surgery | 2002 - 2005, 2011 |
| 3rd Year Bachelor of Dental Surgery | 2006 - 2007 |
| Stream Coordination | |
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| Dental and Health Science II | 1999 - 2007 |
| Diseases and Disorders of the Body III | 2003 - 2011 |
| Dental Science and Practice 2 | 2011 |
| Undergraduate Teaching | ||
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| Biochemistry | Dental & Health Science II | 1993 - 2010 |
| General & Oral Microbiology | Diseases & Disorders of the Body III | 2002 - 2011 |
| Endodontic Microbiology | Clinical Dental Practice IV. | 2002 - 2006 |
| Macromolecules | Human Biology I | 2007 - 2009 |
| Dental Selectives BDS4 | 2002 - 2010 | |
| Dental Selectives BDS5 | 2005 - 2010 | |
| Biochemistry | Human Biology BOH 1 | 2006 - 2007 |
| General Microbiology | Human Biology BOH 1 | 2002 - |
| Oral Microbiology | Human Biology BOH 2 | 2003 - |
| Research Elective | BOH 3 | 2004 - 2008 |
| Research Methodology | Post-graduate Core-course | 2002 - 2007 |
| Dental School Graduate | External Programs | 2004 - 2005 |
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Past Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2015 - 2018 Co-Supervisor Clinical and Microbiological Effects of Probiotics in Experimental Induced Periodontitis Doctor of Philosophy Doctorate Full Time Mrs Simona Gatej 2013 - 2017 Co-Supervisor Ancient DNA Studies of Dental Calculus Doctor of Philosophy Doctorate Full Time Mr Andrew Graham Farrer 2010 - 2013 Co-Supervisor The Diagnosis of White Spot Lesions in Orthodontic Patients Doctor of Clinical Dentistry Doctorate Full Time Dr Balya Sriram 2009 - 2016 Co-Supervisor Proteomic Analysis of Enterococcus faecalis Cell Membrane Proteins under Alkaline Stress Conditions Doctor of Philosophy Doctorate Part Time APrf Peter Cathro 2008 - 2011 Principal Supervisor An Investigation of Porphyromonas gingivalis Peptidylarginine Deiminase: A Putative Virulence Factor in an Animal Model of Inflammation Master of Science in Dentistry Master Full Time Miss Syatirah Najmi Abdullah 2008 - 2011 Co-Supervisor Evaluation of Salivary Flora Acidogenicity Under Acidic Conditions for Prediction of Cariogenic Potential During Fixed Orthodontic Treatment Doctor of Clinical Dentistry Doctorate Full Time Dr Sara Roberts 2008 - 2011 Co-Supervisor An in-vitro Evaluation of the Effectiveness of Endodontic Irrigants, with and without Sonic and Laser Activation, in the Eradication of Enterococcus faecalis Biofilm Doctor of Clinical Dentistry Doctorate Full Time Dr Aaron Nicholas Shiao Ming Seet 2007 - 2010 Principal Supervisor Protein Expression in Fusobacterium nucleatum ATCC 10953 Biofilm Cells Induced by an Alkaline Environment Doctor of Philosophy Doctorate Full Time Dr Jactty Chew
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