Dr Natalie Mills

• Appointments

  Date	Position	Institution name
  2016 - ongoing	Senior Lecturer in Psychiatry	University of Adelaide

• Education

  Date	Institution name	Country	Title
  2016	The University of Queensland	Australia	PhD
  1993	Monash University	Australia	MBBS

• Postgraduate Training

  Date	Title	Institution	Country
  2009 - 2011	Certificate of Advanced Training in Child and Adolescent Psychiatry	Royal Australian and New Zealand College of Psychiatrists	Australia
  2005 - 2005	Diploma in Clinical Psychiatry	Royal College of Physicians of Ireland and Royal College of Surgeons in Ireland	Ireland
  2004 - 2010	FRANZCP	Royal Australian and New Zealand College of Psychiatrists	Australia
  1996 - 2000	FRACGP	Royal Australian College of General Practitioners, East Melbourne	Australia

• Research Interests

  Psychiatry Neuroscience, Behaviour and Brain Health

• Journals

  Year	Citation
  2025	Kamath, S., Sokolenko, E., Collins, K., Chan, N. S. L., Mills, N., Clark, S. R., . . . Joyce, P. (2025). IUPHAR Themed Review: The Gut Microbiome in Schizophrenia.. Pharmacological Research, 211, 107561-1-107561-13. DOI Scopus5 Europe PMC3
  2025	Mills, N. T., Nikolin, S., Glozier, N., Barton, D., Baune, B. T., Fitzgerald, P. B., . . . Loo, C. K. (2025). Effect of ketamine on anxiety: findings from the Ketamine for Adult Depression Study. British Journal of Psychiatry, 1-7. DOI Scopus1
  2025	Davies, E., Mills, N., Montagu, A., Chur-Hansen, A., & Clark, S. (2025). Hybrid simulation and immersive, lived-experience perspectives to shape medical student attitudes towards patients experiencing emotional distress, suicidality, and self-harm. Advances in Simulation, 10(1), 12 pages. DOI
  2025	Amente, L. D., Mills, N. T., Le, T. D., Hyppönen, E., & Lee, S. H. (2025). A latent outcome variable approach for Mendelian randomization using the stochastic expectation maximization algorithm. Human Genetics, 144(5), 559-574. DOI
  2025	Chatterton, M. L., Perez, J. K., Thai, T., Faller, J., Loo, C. K., Glozier, N., . . . Mihalopoulos, C. (2025). Economic evaluation of subcutaneous ketamine injections for treatment resistant depression: A randomised, double-blind, active-controlled trial - The KADS study. Journal of Affective Disorders, 387, 119502-1-119502-10. DOI
  2025	Loo, C., Alonzo, A., Barton, D., Berk, M., Chatterton, M. L., Dong, V., . . . Rodgers, A. (2025). Efficacy and safety of a 4-week course of repeated subcutaneous ketamine injections for treatment-resistant depression (KADS study): Randomised double-blind active-controlled trial: Commentary, author response. British Journal of Psychiatry, 226(5), 317-318. DOI
  2025	Sampson, E., Mills, N. T., Hori, H., Cearns, M., Schwarte, K., Hohoff, C., . . . Baune, B. T. (2025). Long-term characterisation of the relationship between change in depression severity and change in inflammatory markers following inflammation-stratified treatment with vortioxetine augmented with celecoxib or placebo. Brain Behavior and Immunity, 123, 43-56. DOI Scopus3 Europe PMC3
  2024	Loo, C., Glozier, N., Barton, D., Baune, B. T., Mills, N. T., Fitzgerald, P., . . . Rodgers, A. (2024). Efficacy and safety of a 4-week course of repeated subcutaneous ketamine injections for treatment-resistant depression (KADS study): randomised double-blind active-controlled trial - CORRIGENDUM. British Journal of Psychiatry the Journal of Mental Science, 225(2), 349. DOI Scopus1
  2024	Amente, L. D., Mills, N. T., Le, T. D., Hyppönen, E., & Lee, S. H. (2024). Unraveling phenotypic variance in metabolic syndrome through multi-omics. Human Genetics, 143(1), 35-47. DOI Scopus2 Europe PMC2
  2024	Martin, D. M., Harvey, A. J., Baune, B., Berk, M., Carter, G. L., Dong, V., . . . Loo, C. K. (2024). Cognitive outcomes from the randomised, active-controlled Ketamine for Adult Depression Study (KADS). Journal of affective disorders, 352, 163-170. DOI Scopus3 Europe PMC3
  2024	Sampson, E., Kavakbasi, E., Mills, N. T., Hori, H., Schubert, K. O., Fourrier, C., & Baune, B. T. (2024). Emotional Blunting in Depression in the PREDDICT Clinical Trial: Inflammation-Stratified Augmentation of Vortioxetine With Celecoxib. International Journal of Neuropsychopharmacology, 27(3), 11 pages. DOI Scopus1 Europe PMC1
  2023	Kavakbasi, E., Emma, S., Mills, N. T., Hori, H., Schwarte, K., Hohoff, C., . . . Baune, B. T. (2023). Inflammation-stratified augmentation of vortioxetine with celecoxib: results from a double-blind, randomized, placebo-controlled trial in Major Depressive Disorder. Journal of Neurochemistry, 168(9), 1817-1825. DOI Scopus4 Europe PMC3
  2023	Sampson, E., Mills, N. T., Hori, H., Schwarte, K., Hohoff, C., Schubert, O., . . . Baune, B. T. (2023). Exploratory Analysis of the Effects of Celecoxib on Cognitive Function in Vortioxetine-Treated Patients With Major Depressive Disorder in the PREDDICT Study: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.. The Journal of clinical psychiatry, 84(6), 23m14829. DOI Scopus2 Europe PMC1
  2023	Loo, C., Glozier, N., Barton, D., Baune, B., Mills, N., Fitzgerald, P. B., . . . Rodgers, A. (2023). Efficacy and Safety of Repeated Subcutaneous Ketamine Injections for Treatment Resistant Depression - The KADS Study: A Randomised, Double-Blind, Comparator-Controlled Trial. British Journal of Psychiatry, 223(6), 533-541. DOI Scopus38 WoS6 Europe PMC29
  2022	Baune, B. T., Sampson, E., Louise, J., Hori, H., Schubert, K. O., Clark, S. R., . . . Fourrier, C. (2022). Corrigendum to 'No evidence for clinical efficacy of adjunctive celecoxib with vortioxetine in the treatment of depression: A 6-week double-blind placebo controlled randomized trial' [European Neuropsychopharmacology 53 (2021) 34-46].. Eur Neuropsychopharmacol, 64, 61-62. DOI
  2022	Ciobanu, L. G., Stankov, L., Schubert, K. O., Amare, A. T., Jawahar, M. C., Lawrence-Wood, E., . . . Aidman, E. (2022). General intelligence and executive functioning are overlapping but separable at genetic and molecular pathway levels: An analytical review of existing GWAS findings. PLOS ONE, 17(10), e0272368. DOI Scopus2 Europe PMC2
  2022	Thalamuthu, A., Mills, N. T., Berger, K., Minnerup, H., Grotegerd, D., Dannlowski, U., . . . Baune, B. T. (2022). Genome-wide interaction study with major depression identifies novel variants associated with cognitive function.. Mol Psychiatry, 27(2), 1111-1119. DOI Scopus36 WoS15 Europe PMC30
  2021	Enticott, P. G., Barlow, K., Guastella, A. J., Licari, M. K., Rogasch, N. C., Middeldorp, C. M., . . . Fitzgerald, P. B. (2021). Repetitive transcranial magnetic stimulation (rTMS) in autism spectrum disorder: protocol for a multicentre randomised controlled clinical trial. BMJ Open, 11(7), e046830-1-e046830-9. DOI Scopus14 WoS6 Europe PMC10
  2021	Baune, B. T., Sampson, E., Louise, J., Hori, H., Schubert, K. O., Clark, S. R., . . . Fourrier, C. (2021). No evidence for clinical efficacy of adjunctive celecoxib with vortioxetine in the treatment of depression: A 6-week double-blind placebo controlled randomized trial.. Eur Neuropsychopharmacol, 53, 34-46. DOI Scopus42 WoS16 Europe PMC36
  2021	Mills, N. T., Sampson, E., Fourrier, C., & Baune, B. T. (2021). Clinical switching strategies of various antidepressants to Vortioxetine in the PREDDICT trial. The international journal of neuropsychopharmacology, 24(4), 314-321. DOI Scopus5 WoS2 Europe PMC1
  2020	Fourrier, C., Sampson, E., Hori, H., Schubert, K. O., Clark, S., Mills, N. T., & Baune, B. T. (2020). Exploratory study of association between blood immune markers and cognitive symptom severity in major depressive disorder: Stratification by body mass index status. Brain, Behavior, and Immunity, 88, 242-251. DOI Scopus10 WoS7 Europe PMC7
  2020	Parsons, C., Roberts, R., & Mills, N. T. (2020). Review: Inflammation and anxiety-based disorders in children and adolescents - a systematic review and meta-analysis.. Child and adolescent mental health, 26(2), 143-156. DOI Scopus13 WoS9 Europe PMC13
  2019	Knight, M. J., Mills, N. T., & Baune, B. T. (2019). Contemporary methods of improving cognitive dysfunction in clinical depression.. Expert review of neurotherapeutics, 19(5), 431-443. DOI Scopus14 WoS7 Europe PMC4
  2019	Ni, G., Amare, A. T., Zhou, X., Mills, N., Gratten, J., & Lee, S. H. (2019). The genetic relationship between female reproductive traits and six psychiatric disorders. Scientific Reports, 9(1), 12041-1-12041-12. DOI Scopus22 WoS11 Europe PMC18
  2019	Knight, M. J., Fourrier, C., Lyrtzis, E., Aboustate, N., Sampson, E., Hori, H., . . . Baune, B. T. (2019). Cognitive deficits in the THINC-integrated tool (THINC-it) are associated with psychosocial dysfunction in patients with major depressive disorder. Journal of Clinical Psychiatry, 80(1), 18m12472-1-18m12472-8. DOI Scopus19 WoS10 Europe PMC8
  2018	Ni, G., Amare, A., Zhou, X., Mills, N., Gratten, J., & Hong Lee, S. (2018). The genetic relationship between female reproductive traits and six psychiatric disorders. DOI
  2018	Fourrier, C., Sampson, E., Mills, N. T., & Baune, B. T. (2018). Anti-inflammatory treatment of depression: study protocol for a randomised controlled trial of vortioxetine augmented with celecoxib or placebo. Trials, 19(1), 447-1-447-14. DOI Scopus59 WoS37 Europe PMC39
  2018	Van der Auwera, S., Peyrot, W., Milaneschi, Y., Hertel, J., Baune, B., Breen, G., . . . Grabe, H. (2018). Genome-wide gene-environment interaction in depression: a systematic evaluation of candidate genes: the childhood trauma working-group of PGC-MDD. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 177(1), 40-49. DOI Scopus59 WoS47 Europe PMC34
  2018	Couvy-Duchesne, B., O'Callaghan, V., Parker, R., Mills, N., Kirk, K., Scott, J., . . . Gillespie, N. (2018). Nineteen and Up study (19Up): understanding pathways to mental health disorders in young Australian twins. BMJ open, 8(3), 1-12. DOI Scopus26 WoS17 Europe PMC16
  2018	Cambridge, O., Knight, M., Mills, N., & Baune, B. (2018). The clinical relationship between cognitive impairment and psychosocial functioning in major depressive disorder: A systematic review. Psychiatry Research, 269, 157-171. DOI Scopus133 WoS92 Europe PMC70
  2017	Renteria, M., Schmaal, L., Hibar, D., Couvy-Duchesne, B., Strike, L., Mills, N., . . . Hickie, I. (2017). Subcortical brain structure and suicidal behaviour in major depressive disorder: a meta-analysis from the ENIGMA-MDD working group. Translational Psychiatry, 7(5), e1116-1-e1116-7. DOI Scopus77 WoS59 Europe PMC60
  2017	Schmaal, L., Hibar, D. P., Sämann, P. G., Hall, G. B., Baune, B. T., Jahanshad, N., . . . Veltman, D. J. (2017). Cortical abnormalities in adults and adolescents with major depression based on brain scans from 20 cohorts worldwide in the ENIGMA Major Depressive Disorder Working Group. Molecular Psychiatry, 22(6), 10 pages. DOI Scopus895 WoS635 Europe PMC702
  2017	Mills, N., Maier, R., Whitfield, J., Wright, M., Colodro-Conde, L., Byrne, E., . . . Benyamin, B. (2017). Investigating the relationship between iron and depression. Journal of Psychiatric Research, 94, 148-155. DOI Scopus10 WoS4 Europe PMC7
  2016	Schmaal, L., Veltman, D., van Erp, T., Saemann, P., Frodl, T., Jahanshad, N., . . . Hibar, D. (2016). Subcortical brain alterations in major depressive disorder: findings from the ENIGMA Major Depressive Disorder working group. MOLECULAR PSYCHIATRY, 21(6), 806-812. DOI Scopus826 WoS320 Europe PMC650
  2015	Mills, N. T., Wright, M. J., Henders, A. K., Eyles, D. W., Baune, B. T., McGrath, J. J., . . . Vinkhuyzen, A. A. E. (2015). Heritability of transforming growth factor-β1 and tumor necrosis factor-receptor type 1 expression and vitamin D levels in healthy adolescent twins. Twin Research and Human Genetics, 18(1), 28-35. DOI Scopus20 WoS17 Europe PMC15
  2013	Mills, N., Scott, J., Wray, N., Cohen-Woods, S., & Baune, B. (2013). Research review: the role of cytokines in depression in adolescents: a systematic review. Journal of Child Psychology and Psychiatry and Allied Disciplines, 54(8), 816-835. DOI Scopus81 WoS68 Europe PMC56

• Conference Papers

  Year	Citation
  2025	Loo, C., Glozier, N., Barton, D., Baune, B., Mills, N., Fitzgerald, P., . . . Rodgers, A. (2025). EXTENDING KNOWLEDGE AND CLINICAL EXPERIENCE ON THE USE OF KETAMINE. In AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY Vol. 59 (pp. 1 page). SAGE PUBLICATIONS LTD.
  2025	Mills, N., Nikolin, S., Glozier, N., Barton, D., Baune, B., Fitzgerald, P., . . . Loo, C. (2025). EFFECT OF KETAMINE ON ANXIETY: FINDINGS FROM THE KETAMINE FOR ADULT DEPRESSION STUDY (KADS). In AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY Vol. 59 (pp. 1 page). SAGE PUBLICATIONS LTD.
  2024	Mills, N., Parsons, C., Sharkey, D., Erginbas, A., Roberts, R., Scott, J., . . . Jawahar, M. (2024). INVESTIGATING THE RELATIONSHIP BETWEEN PERIPHERAL INFLAMMATORY MARKERS AND ANXIETY DISORDERS. In AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY Vol. 58 (pp. 174-175). SAGE PUBLICATIONS LTD.
  2022	Clark, S. R., Mills, N., Toben, C., Jawaha, C., & Galletly, C. (2022). MENTAL HEALTH MEDICAL EDUCATION LEAD: UNIVERSITY OF ADELAIDE, ADELAIDE - EVALUATING TECHNOLOGICAL SOLUTIONS TO MENTAL HEALTH TEACHING AND ASSESSMENT DURING THE PANDEMIC. In AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY Vol. 56 (pp. 150). SAGE PUBLICATIONS LTD.
  2022	Turner, M., Nasti, J., & Mills, N. (2022). AUSTRALASIAN PSYCHOPHARMACOLOGY INTEREST GROUP: 2022 UPDATE - NEW AND OLD MEDICATIONS: WHERE ARE WE UP TO?. In AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY Vol. 56 (pp. 80-81). SAGE PUBLICATIONS LTD.
  2015	Schmaal, L., Veltman, D. J., van Erp, T. G. M., Penninx, B. W. J. H., Thompson, P. M., & Hibar, D. P. (2015). Subcortical Brain Alterations in Major Depressive Disorder: Findings from the ENIGMA Major Depressive Disorder Working Group. In BIOLOGICAL PSYCHIATRY Vol. 77 (pp. 1 page). Toronto, CANADA: ELSEVIER SCIENCE INC. WoS313
  2015	Schmaal, L., Veltman, D. J., Van Erp, T. G., Saemann, P. G., Frodl, T., Jahanshad, N., . . . Hibar, D. P. (2015). Structural brain alterations in major depression: findings from the ENIGMA Major Depressive Disorder Working Group. In EUROPEAN NEUROPSYCHOPHARMACOLOGY Vol. 25 (pp. S394-S395). Amsterdam, NETHERLANDS: ELSEVIER SCIENCE BV. DOI WoS1

• Conference Items

  Year	Citation
  2024	Martin, D., Harvey, A., Baune, B., Berk, M., Carter, G., Dong, V., . . . Loo, C. (2024). Cognitive Outcomes Following a Course of Racemic Ketamine: Results From the Randomised, Active-Controlled Ketamine for Adult Depression Study (KADS). Poster session presented at the meeting of Abstracts of the 79th Annual Meeting of the Society of Biological Psychiatry (SOBP 2024) as published in Biological Psychiatry. Austin, Texas, USA: Elsevier. DOI
  2021	Turner, M., Kotze, B., & Mills, N. (2021). PSYCHOPHARMACOLOGY UPDATE: RECENT ADVANCES FOR CHILDREN AND ADOLESCENTS AND IMPLICATIONS FOR PRACTICE. Poster session presented at the meeting of AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY. SAGE PUBLICATIONS LTD.
  2021	Ciobanu, L., Stankov, L., Heathcote, A., Clark, S., Breen, J., Rogasch, N., . . . Aidman, E. (2021). Mapping the genetic architectures of cognitive functioning. Poster session presented at the meeting of GeneMappers 2021. Virtual.
  2020	Ciobanu, L., Schubert, O., Amare, A., Jawahar, C., Lawrence-Woods, E., Mills, N., . . . Aidman, E. (2020). P9. MAPPING THE GENETIC ARCHITECTURES OF COGNITIVE FITNESS: CAN GWAS DATA DIFFERENTIATE EXECUTIVE FUNCTIONING FROM GENERAL COGNITIVE ABILITY?. Poster session presented at the meeting of Nature Neurogenetics. New York.
  2019	Baune, B., Sampson, E., Mills, N., Lyrtzis, E., Aboustate, N., Hori, H., . . . Fourrier, C. (2019). Vortioxetine with or without anti-inflammatory augmentation improves mood, cognition and functioning in MDD patients: results from the PREDDICT clinical trial. Poster session presented at the meeting of RANZCP. Hobart.
  2018	Baune, B., Mills, N., Sampson, E., Aboustate, N., & Fourrier, C. (2018). Switching strategies for Vortioxetine in the PREDDICT Study. Poster session presented at the meeting of Biological Psychiatry Australia. Adelaide.

Teaching and co-ordinator of University of Adelaide Year 4 MBBS Psychiatry course (since January 2020)

Teaching and co-convenor of University of Adelaide Year 4 MBBS Psychiatry course (August 2016 - December 2019)

Case-based learning tutor University of Adelaide Year 3 MBBS (semester 2, 2019)

Lecturer University of Adelaide, Biological Psychiatry course (2016 - 2024)

• Other Supervision Activities

  Date	Role	Research Topic	Location	Program	Supervision Type	Student Load	Student Name
  2022 - 2022	Co-Supervisor	The association of anxiety symptom severity and panic attacks with inflammation	University of Adelaide	Psychology	Honours	-	Aylin Erginbas
  2019 - 2019	Co-Supervisor	Inflammation and anxiety-based disorders in children and adolescents: a systematic review and meta-analysis	The University of Adelaide, School of Psychology	-	Honours	-	Chelsea Parsons
  2017 - 2017	Co-Supervisor	Exploring the relationship between cognitive impairment and psychosocial functioning in Major Depressive Disorder	The University of Adelaide	Adelaide Medical School	Honours	-	Olivia Cambridge

• Committee Memberships

  Date	Role	Committee	Institution	Country
  2023 - ongoing	Member	MRFF Grant Assessment Committee	University of Adelaide	Australia
  2022 - 2022	Vice-Chair	Year 4 & 5 MBBS Written Exam Committee	University of Adelaide	Australia
  2021 - ongoing	Member	University of Adelaide Year 4 MBBS Written exam subcommittee	University of Adelaide	Australia
  2021 - ongoing	Member	University of Adelaide Year 4 MBBS OSCE Subcommittee	University of Adelaide	Australia
  2018 - ongoing	Member	Adelaide Medical School MBBS Research Committee	University of Adelaide	Australia
  2018 - ongoing	Member	Faculty Seminar Series Organising Committee	University of Adelaide	Australia
  2015 - 2015	Member	Organising Committee 2015 Society for Mental Health Research Conference	Society for Mental Health Research	Australia
  2014 - 2015	Member	Scientific Program Committee 2015 Royal Australian and New Zealand College of Psychiatrists Congress	Royal Australian and New Zealand College of Psychiatrists	Australia
  2014 - 2014	Member	Organising Committee Royal Australian and New Zealand College of Psychiatrists Faculty of Child and Adolescent Psychiatry Conference	Royal Australian and New Zealand College of Psychiatrists	Australia
  2012 - 2012	Member	Royal Australian and New Zealand College of Psychiatrists, Queensland Faculty of Child and Adolescent Psychiatry Conference Organising Committee	RANZCP	Australia

• Community Engagement

  Date	Title	Engagement Type	Institution	Country
  2018 - 2018	Radio interview	Scientific Community Engagement	QIMR Berghofer Medical Research Institute	-

• Offices Held

  Date	Office Name	Institution	Country
  2014 - 2016	Child and Adolescent Psychiatrist	Royal Brisbane and Women's Hospital	Australia
  2012 - 2014	Child and Adolescent Psychiatrist	Ipswich Hospital	Australia

• Position: Senior Lecturer in Psychiatry
• Phone: 83137369
• Email: natalie.mills@adelaide.edu.au
• Campus: North Terrace
• Building: Adelaide Health and Medical Sciences, floor 6
• Org Unit: Medical Specialties