Dr Nan Hao

• Appointments

  Date	Position	Institution name
  2024 - ongoing	Lecturer	University of Adelaide
  2017 - 2024	Synthetic Biology Future Science Fellow (Level B)	University of Adelaide and CSIRO joint appointment
  2017 - 2017	ARC DECRA Fellow (Level B)	University of Adelaide, Adelaide
  2015 - 2016	ARC DECRA Fellow (Level A)	University of Adelaide, Adelaide
  2012 - 2014	Postdoc Research Fellow (Level A)	University of Adelaide, Adelaide
  2007 - 2008	Research Assistant	University of Adelaide, Adelaide
  2006 - 2007	Research Assistant	University of Adelaide, Adelaide

• Awards and Achievements

  Date	Type	Title	Institution Name	Country	Amount
  2021	Award	ECR Presentation Award	ASBMB Adelaide Protein Group (APG)	Australia	A$1000
  2019	Award	ECR poster award	Synthetic Biology Australasia (SBA)	Australia	A$200
  2019	Award	YSP travel fellowship, 27th FAOBMB & 44th MSBMB Conference	Federation of Asian and Oceanian Biochemist & Molecular Biologist	Malaysia	A$3000
  2017	Research Award	Executive Dean's Order of Merit, Daniel Walker Medal for Early Career Research Excellence	The University of Adelaide	Australia	-
  2017	Achievement	Finalist for ECR presentation	ASBMB Adelaide Protein Group (APG)	Australia	-
  2017	Invitation	Invited Seminar Presentation	Epigenetics Consortium of South Australia and Adelaide RNA Special Interest Group Seminar	Australia	-
  2017	Invitation	Invited Pitch	US Department of Defence Representative	Australia	-
  2016	Award	Best presentation/poster in the ECR category	OCE Cutting Edge Conference in Synthetic Biology	Australia	A$ 200
  2015	Invitation	Invited Speaker	School of Biological Sciences Inaugural Research Day	-	-
  2015	Fellowship	ASBMB travel fellowship	ASBMB	Australia	A$ 3000
  2012	Award	Poster Award	ASBMB ComBio conference	Australia	A$ 200
  2012	Research Award	Postgraduate Academic Achievement Award	The University of Adelaide	Australia	A$ 500
  2012	Award	Writing up Award	The University of Adelaide	Australia	A$ 3000
  2011	Award	Chinese government award for outstanding self-financed students abroad	China Scholarship Council	China	US$ 6000
  2011	Award	Poster prize	ASBMB Adelaide Protein Group	Australia	A$ 200
  2010	Achievement	Finalist	ASBMB Adelaide Protein Group Student Event	Australia	-
  2008	Scholarship	Adelaide Graduate Fee Scholarship - PhD scholarship	The University of Adelaide	-	-
  2007	Award	The Brian & Heather Forster Prize in Biochemistry - Top Honours	The University of Adelaide	Australia	-
  2005	Scholarship	Summer Vacation Scholarship	The University of Adelaide	Australia	-

• Language Competencies

  Language	Competency
  Chinese (Mandarin)	Can read, write, speak, understand spoken and peer review
  English	Can read, write, speak, understand spoken and peer review

• Education

  Date	Institution name	Country	Title
  2008 - 2012	The University of Adelaide	Australia	PhD in Biochemistry
  2007 - 2007	The University of Adelaide	Australia	B. Sc. (Honours, First class)
  2004 - 2006	The University of Adelaide	Australia	B. Sc. (Biomedical Science)

• Research Interests

  Biochemistry & Molecular Biology Synthetic Biology

• Journals

  Year	Citation
  2024	Li, J., Hao, N., Han, J., Zhang, M., Li, X., & Yang, N. (2024). ZKSCAN3 drives tumor metastasis via integrin β4/FAK/AKT mediated epithelial-mesenchymal transition in hepatocellular carcinoma. CANCER CELL INTERNATIONAL, 24(1), 1 page. DOI
  2023	Hao, N., Donnelly, A. J., Dodd, I. B., & Shearwin, K. E. (2023). When push comes to shove - RNA polymerase and DNA-bound protein roadblocks. Biophysical Reviews, 15(3), 355-366. DOI Scopus2 WoS1 Europe PMC3
  2021	Hao, N., Sullivan, A. E., Shearwin, K. E., & Dodd, I. B. (2021). The loopometer: a quantitative in vivo assay for DNA-looping proteins. Nucleic Acids Research, 49(7), 1-16. DOI Scopus5 WoS5 Europe PMC4
  2021	Hao, N., Chen, Q., Dodd, I. B., & Shearwin, K. E. (2021). The pIT5 Plasmid Series, an Improved Toolkit for Repeated Genome Integration in E. coli. ACS Synthetic Biology, 10(7), 1633-1639. DOI Scopus2 WoS1 Europe PMC2
  2021	Hao, N., Agnew, D., Krishna, S., Dodd, I. B., & Shearwin, K. E. (2021). Analysis of infection time courses shows CII levels determine the frequency of lysogeny in phage 186. Pharmaceuticals, 14(10), 998-1-998-14. DOI Scopus2 Europe PMC1
  2019	Hoffmann, S. A., Hao, N., Shearwin, K. E., & Arndt, K. M. (2019). Characterizing transcriptional interference between converging genes in bacteria. ACS Synthetic Biology, 8(3), 466-473. DOI Scopus10 WoS9 Europe PMC6
  2019	Hao, N., Shearwin, K. E., & Dodd, I. B. (2019). Positive and negative control of enhancer-promoter interactions by other DNA loops generates specificity and tunability. Cell Reports, 26(9), 2419-2433.e1–e3. DOI Scopus20 WoS18 Europe PMC15
  2019	Hao, N., Crooks, M. T., Palmer, A. C., Dodd, I. B., & Shearwin, K. E. (2019). RNA polymerase pausing at a protein roadblock can enhance transcriptional interference by promoter occlusion. FEBS Letters, 593(9), 903-917. DOI Scopus6 WoS3 Europe PMC3
  2017	Hao, N., Palmer, A. C., Dodd, I. B., & Shearwin, K. E. (2017). Directing traffic on DNA - How transcription factors relieve or induce transcriptional interference. Transcription, 8(2), 120-125. DOI Scopus19 WoS17 Europe PMC15
  2017	Hao, N., Sneppen, K., Shearwin, K., & Dodd, I. (2017). Efficient chromosomal-scale DNA looping in Escherichia coli using multiple DNA-looping elements. Nucleic Acids Research, 45(9), 5074-5085. DOI Scopus6 WoS6 Europe PMC3
  2017	Hao, N., & Shearwin, K. E. (2017). Hidden secrets of sigma54 promoters revealed. Trends in Biochemical Sciences, 42(12), 931-932. DOI
  2017	Hao, N., Shearwin, K., & Dodd, I. (2017). Programmable DNA looping using engineered bivalent dCas9 complexes. Nature Communications, 8(1), 1-12. DOI Scopus59 WoS47 Europe PMC39
  2016	Silginer, M., Burghardt, I., Gramatzki, D., Bunse, L., Leske, H., Rushing, E., . . . Roth, P. (2016). The aryl hydrocarbon receptor links integrin signaling to the TGF-β pathway. Oncogene, 35(25), 3260-3271. DOI Scopus50 WoS43 Europe PMC30
  2016	Hao, N., Palmer, A., Ahlgren-Berg, A., Shearwin, K., & Dodd, I. (2016). The role of repressor kinetics in relief of transcriptional interference between convergent promoters. Nucleic Acids Research, 44(14), 6625-6638. DOI Scopus22 WoS16 Europe PMC13
  2014	Hao, N., Krishna, S., Ahlgren-Berg, A., Cutts, E., Shearwin, K., & Dodd, I. (2014). Road rules for traffic on DNA - systematic analysis of transcriptional roadblocking in vivo. Nucleic Acids Research, 42(14), 8861-8872. DOI Scopus35 WoS32 Europe PMC20
  2013	Hao, N., & Whitelaw, M. (2013). The emerging roles of AhR in physiology and immunity. Biochemical Pharmacology, 86(5), 561-570. DOI Scopus167 WoS145 Europe PMC111
  2013	Hao, N., Bhakti, V., Peet, D., & Whitelaw, M. (2013). Reciprocal regulation of the basic helix-loop-helix/Per-Arnt-Sim partner proteins, Arnt and Arnt2, during neuronal differentiation. Nucleic Acids Research, 41(11), 5626-5638. DOI Scopus28 WoS24 Europe PMC26
  2012	Hao, N., Lee, K., Furness, S., Bosdotter, C., Poellinger, L., & Whitelaw, M. (2012). Xenobiotics and loss of cell adhesion drive distinct transcriptional outcomes by aryl hydrocarbon receptor signaling. Molecular Pharmacology, 82(6), 1082-1093. DOI Scopus25 WoS21 Europe PMC19
  2011	Hao, N., Whitelaw, M. L., Shearwin, K. E., Dodd, I. B., & Chapman-Smith, A. (2011). Identification of residues in the N-terminal PAS domains important for dimerization of Arnt and AhR. Nucleic Acids Research, 39(9), 3695-3709. DOI Scopus34 WoS28 Europe PMC29
  2010	Whelan, F., Hao, N., Furness, S., Whitelaw, M., & Chapman-Smith, A. (2010). Amino acid substitutions in the aryl hydrocarbon receptor ligand binding domain reveal YH439 as an atypical AhR activator. Molecular Pharmacology, 77(6), 1037-1046. DOI Scopus21 WoS17 Europe PMC17
  2008	Wang, W. -G., & Hao, N. (2008). ON MIXED AND COMPONENTWISE CONDITION NUMBERS FOR HYPERBOLIC <i>QR</i> FACTORIZATION. FILOMAT, 22(1), 183-192. WoS1

• Conference Items

  Year	Citation
  2023	Hao, N. (2023). Re-imagining Phage Biology: A Synthetic Biology Perspective. Poster session presented at the meeting of ENT Mini Symposium. Adelaide.
  2022	Hao, N. (2022). Synthetic Biology Tools for Repeated Genome Integration in E. coli. Poster session presented at the meeting of ASBMB ComBio 2022. Melbourne.
  2021	Hao, N. (2021). The pIT5 Plasmid Series, an Improved Toolkit for Repeated Genome Integration in E. coli. Poster session presented at the meeting of ASBMB Adelaide Protein Group (APG) Awards Fest. Adelaide.
  2019	Hao, N. (2019). Expanding the Synthetic Biology Toolbox. Poster session presented at the meeting of School of Biological Sciences Research Day. Adelaide.
  2019	Hao, N., Shearwin, K. E., & Dodd, I. B. (2019). Programmable DNA looping using engineered bivalent dCas9 complexes. Poster session presented at the meeting of Abstracts of the 27th FAOBMB & 44th MSBMB Conference. Kuala Lumpur, Malaysia: Malaysian Society for Biochemistry & Molecular Biology (MSBMB).
  2019	Hao, N. (2019). Positive and Negative Control of Enhancer-Promoter Interactions by Other DNA Loops Generates Specificity and Tunability. Poster session presented at the meeting of Synthetic Biology Australasia conference 2019. Brisbane.
  2017	Hao, N., Shearwin, K., & Dodd, I. (2017). Understanding and Manipulating Chromosomal-Scale DNA Looping in Escherichia coli. Poster session presented at the meeting of 2017 Synthetic Biology: Engineering, Evolution & Design (SEED) : Proceedings. Vancouver, Canada.
  2017	Hao, N. (2017). Programmable DNA looping using engineered bivalent dCas9 complexes. Poster session presented at the meeting of ASBMB ComBio conference. Adelaide.
  2017	Hao, N. (2017). Programmable DNA looping using engineered bivalent dCas9 complexes. Poster session presented at the meeting of Synthetic Biology Australasia Conference. Sydney.
  2017	Hao, N., Priest, D., Dodd, I., & Shearwin, K. (2017). Programmable DNA looping in vivo. Poster session presented at the meeting of Australia-China Symposium on Synthetic Biology. Brisbane.
  2016	Hao, N., Shearwin, K., & Dodd, I. (2016). Road Rules for Traffic on DNA: Gene Regulation by Encounters between Transcribing RNA Polymerases and DNA-bound Proteins. Poster session presented at the meeting of Synthetic Biology: Engineering, Evolution & Design (SEED). Chicago, USA.
  2016	Hao, N., Shearwin, K., & Dodd, I. (2016). Understand DNA looping in vivo - a synthetic biology approach. Poster session presented at the meeting of OCE Cutting Edge Conference in Synthetic Biology. Canberra.
  2015	Hao, N., Krishna, S., Shearwin, K., & Dodd, I. (2015). Road Rules for Traffic on DNA: Gene Regulation by Encounters between Transcribing RNA Polymerases and DNA-bound Proteins. Poster session presented at the meeting of 2nd International Synthetic & Systems Biology Summer School. Taormina - Sicily, Italy.
  2015	Hao, N. (2015). Understanding and manipulating long-range DNA looping in vivo. Poster session presented at the meeting of ASBMB ComBio conference. Melbourne.
  2014	Hao, N. (2014). Road Rules for Traffic on DNA: Gene Regulation by Encounters between Transcribing RNA Polymerases and DNA-bound Proteins. Poster session presented at the meeting of The 13th Asian Conference on Transcription. Melbourne.
  2012	Hao, N., Shearwin, K., Dodd, I., Whitelaw, M., & Chapman-Smith, A. (2012). Reverse Bacterial Two Hybrid: A New Tool for Studying Dimeric Protein Interactions. Poster session presented at the meeting of ASBMB ComBio conference. Adelaide.
  2009	Hao, N., Shearwin., Dodd, I., Whitelaw, M., & Chapman-Smith, A. (2009). Reverse Bacterial two Hybrid (RevB2H) method for studying protein-protein interactions. Poster session presented at the meeting of Network in Genes and Environment in Development (NGED) Forum. Palm Cove, Queensland.
  2009	Hao, N., Shearwin, K., Dodd, I., Whitelaw, M., & Chapman-smith, A. (2009). A novel Reverse Bacterial two Hybrid (RevB2H) method for studying protein-protein interactions and screening for potential therapeutics. Poster session presented at the meeting of Australian Society for Medical Research (ASMR) SA Scientific Meeting. Adelaide.

• Theses

  Year	Citation
  2012	Hao, N. (2012). Regulation of Eukaryotic Transcription by bHLH/PAS Transcription Factors AhR and Arnt. (PhD Thesis, The University of Adelaide).
  2007	Hao, N. (2007). Searching for HIF-1α/Arnt PAS Domain Interacting Proteins. (The University of Adelaide).

• Internet Publications

  Year	Citation
  2019	Hao, N. (2019). Conference report, Aspiring Meeting of Young Researchers in Kuala Lumpur. Australian Biochemist.
  2015	Hao, N. (2015). Science Under the Volcano - Australian Biochemist Magazine. Australian Society for Biochemistry and Molecular Biology Inc..

Postgraduate Teaching

BIOTECH_7003 Advanced Research Techniques

BIOTECH_7008 Applied Biotechnology Research and Design

Laboratory placement supervision

2024: Angela Kloutsiniotis, Kaitlin Turland, Hugh Evans, Jack Basso, Sophie Loveys and Madeline Fechner

2023: Sophie Loveys and Amal Mostafa

2022: Sarah Eisemann, Deannon Branch, Julia Leeflang, and Jayden Revink

2021: Jannath Hera, and Sarah Eisemann

2020: Alix Harlington

2019: Emma Becroft

2018: Grace Tulysewski, and Smriti Singh

2017: Grace Tulysewski

2016: Emi Schutz, Daniel Reed

2015: Alejandra Isabel

2014: Trang Pham, Jade Foeng, Andrew J. Hayes, Queenie Tangseefa, Dominique Jackson

2013: Jia Quyen Truong‎, Byron Shue

2012: Duncan McKenzie

2011: Benjamin Lee (exchange student from Singapore)

2010: Lauren A. Watkins

Undergraduate Teaching

Human Perspectives (SGDE)

Honours in Biochemistry (research grant proposal and thesis assessment)

Honours in Health and Medical Sciences (research grant proposal and thesis assessment)

Undergraduate practical demonstrating

2010 semester 2          Level II MBS Practical series B

2010 semester 1          Level III Biochemistry course

2010 semester 1          Level II MBS Practical series A

2010 semester 1          Level II MBS Practical series C

2009 semester 2          Level II MBS Practical series B

2009 semester 1          Level III Biochemistry course

2009 semester 1          Level II MBS Practical series A

2008 semester 2          Level II MBS Practical series B

2008 semester 1          Level III Biochemistry course

• Current Higher Degree by Research Supervision (University of Adelaide)

  Date	Role	Research Topic	Program	Degree Type	Student Load	Student Name
  2023	Co-Supervisor	Study of bacteriophage protein structures for the production of improved antimicrobial agents	Master of Philosophy	Master	Full Time	Ms Sarah Jayne Eisemann

• Past Higher Degree by Research Supervision (University of Adelaide)

  Date	Role	Research Topic	Program	Degree Type	Student Load	Student Name
  2018 - 2024	Co-Supervisor	Development of the PHEARLESS system and its application for directed protein mutagenesis and characterisation of putative endolysin activity	Doctor of Philosophy	Doctorate	Full Time	Miss Hannah Rose Bonham
  2017 - 2021	Co-Supervisor	Investigating catalytically inactive Cas proteins as transcriptional roadblocks	Doctor of Philosophy	Doctorate	Full Time	Miss Alana Jane Donnelly

• Memberships

  Date	Role	Membership	Country
  2017 - ongoing	Member	Australian Academy of Science EMCR Forum	Australia
  2016 - ongoing	Member	Synthetic Biology Australasia (SBA)	Australia
  2010 - ongoing	Member	Australian Society for Biochemistry and Molecular Biology (ASBMB)	Australia

• Position: Lecturer
• Phone: 83137598
• Email: nan.hao@adelaide.edu.au
• Fax: 83134362
• Campus: North Terrace
• Building: The Braggs, floor Second Floor
• Room: 2.52
• Org Unit: School of Biological Sciences