Mr Mohammad Ismail

Higher Degree by Research Candidate

School of Pharmacy and Biomedical Sciences

College of Health


I'm a PhD candidate in the Prostate Cancer Research Group at SAHMRI, under the supervision of Dr. Zeyad Nassar and led by Professor Lisa Butler. My research centers on investigating the genetic landscape of prostate cancer, specifically targeting key metabolic pathways in prostate cancer. I'm deeply passionate about this endeavor and excited to contribute to our team's mission.

Date Position Institution name
2019 - 2022 Research Assisstant Cell Therapy Center, Amman
2017 - 2018 Medical Laboratory Technician AL-Istiashari Hospita;

Language Competency
Arabic Can read, write, speak and understand spoken
English Can read, write, speak and understand spoken

Date Institution name Country Title
2018 - 2021 The University of Jordan Jordan Masters Degree
2013 - 2017 Hashemite University Jordan Bachelors Drgree

Year Citation
2026 Ababneh, N. A., Gharandouq, M. H., Ismail, M. A., AlDiqs, R., Hamdan, O., Musa, Q., . . . Saleh, T. (2026). Niacin Protects iPSC-Derived Neurons from Chemotherapy-Induced Toxicity. Neurotoxicity Research, 44(2), 15 pages.
DOI
2025 Hussein, S. A., Ababneh, N. A., Tarawneh, N., Ismail, M. A., Awidi, A., & Abdalla, S. (2025). Antitumor Effects of Quercetin and Luteolin in A375 Cutaneous Melanoma Cell Line Are Mediated by Upregulation of P-ERK, c-Myc, and the Upstream GPER. Life, 15(3), 21 pages.
DOI Scopus9 WoS9 Europe PMC6
2025 Gharandouq, M. H., Ismail, M. A., Saleh, T., Zihlif, M., & Ababneh, N. A. (2025). Metformin Protects Human Induced Pluripotent Stem Cell (hiPSC)-Derived Neurons from Oxidative Damage Through Antioxidant Mechanisms. Neurotoxicity Research, 43(2), 17 pages.
DOI Scopus3 WoS3 Europe PMC1
2025 Aldiqs, R., Nashwan, S., Ismail, M. A., Saleh, T., Barham, R., Zihlif, M., & Ababneh, N. A. (2025). Effect of exosomes derived from induced and human adipose tissue-derived mesenchymal stem cells on human cancer cells. Journal of Biosciences, 50(2), 15 pages.
DOI Scopus2 WoS2
2025 Nashwan, S., Ismail, M. A., Saleh, T., Hadidi, S. A., Alwohoush, E., Sarhan, M., . . . Ababneh, N. A. (2025). Comparative analysis of extracellular vesicles from induced and adipose-derived Mesenchymal Stem Cells: Implications for regenerative medicine. Plos One, 20(6 June), 16 pages.
DOI Scopus2 WoS3 Europe PMC2
2025 Ababneh, N. A., AlDiqs, R., Nashwan, S., Ismail, M. A., Barham, R., Alatoom, R. M., . . . Saleh, T. (2025). Exosomes Derived from Induced and Wharton’s Jelly-Derived Mesenchymal Stem Cells Promote Senescence-like Features and Migration in Cancer Cells. International Journal of Molecular Sciences, 26(13), 18 pages.
DOI
2025 Ababneh, N. A., AlDiqs, R., Nashwan, S., Ismail, M. A., Barham, R., Nairat, F., . . . Awidi, A. (2025). hPL-conditioned MSC-derived extracellular vesicles exhibit enhanced anticancer effects on MCF7 and A549 cells. Future Science Oa, 11(1), 16 pages.
DOI
2025 Ababneh, N. A., AlDiqs, R., Gharandouq, M. H., Ismail, M. A., Barham, R., Nairat, F., . . . Saleh, T. (2025). Coenzyme Q10 Ameliorates Chemotherapy-Induced Neurotoxicity in iPSC-Derived Neurons by Reducing Oxidative Stress. International Journal of Molecular Sciences, 26(19), 14 pages.
DOI
2025 Ababneh, N. A., Nashwan, S., AlDiqs, R., Ismail, M. A., Abdulelah, A. A., Abu-Humaidan, A. H. A., . . . Awidi, A. (2025). Cancer cell-dependent increase in senescence-like populations following exosome treatment from bone marrow and induced pluripotent stem cell-derived mesenchymal stem cells. World Journal of Stem Cells, 17(11), 1-20.
DOI WoS1 Europe PMC1
2025 Ababneh, N. A., Alwohoush, E., Aldiqs, R., Ismail, M. A., Al-Kurdi, B., Barham, R., . . . Awidi, A. (2025). Impact of differentiation protocols on the functionality of mesenchymal stem cells derived from induced pluripotent stem cells. WORLD JOURNAL OF STEM CELLS, 17(12), 18 pages.
DOI WoS2
2024 Alwohoush, E., Ismail, M. A., Al-Kurdi, B., Barham, R., Al Hadidi, S., Awidi, A., & Ababneh, N. A. (2024). Effect of hypoxia on proliferation and differentiation of induced pluripotent stem cell-derived mesenchymal stem cells. Heliyon, 10(19), e38857.
DOI
2024 Al-Asmar, A. A., Abuarqoub, D., Ababneh, N., Jafar, H., Zalloum, S., Ismail, M., . . . Awidi, A. (2024). Potential Effects of Photobiomodulation Therapy on Human Dental Pulp Stem Cells. APPLIED SCIENCES-BASEL, 14(1), 14 pages.
DOI WoS2
2024 Abu-Humaidan, A. H. A., Ismail, M. A., Ahmad, F. M., Al Shboul, S., Barham, R., Tadros, J. S., . . . Saleh, T. (2024). Therapy-induced senescent cancer cells exhibit complement activation and increased complement regulatory protein expression. Immunology and Cell Biology, 102(4), 240-255.
DOI Scopus7 WoS8 Europe PMC8
2024 Saleh, T., Naffa, R., Barakat, N. A., Ismail, M. A., Alotaibi, M. R., & Alsalem, M. (2024). Cisplatin Provokes Peripheral Nociception and Neuronal Features of Therapy-Induced Senescence and Calcium Dysregulation in Rats. Neurotoxicity Research, 42(1), 15 pages.
DOI Scopus8 WoS8 Europe PMC7
2023 Alrabayah, M., Massad, I. M., Imraish, A., Jarrar, Y., Massad, F., Guzu, H., . . . Zihlif, M. (2023). Effects of <i>CYP2B6</i> Genetic Variants on the Propofol Dose and Response among Jordanian Arabic Patients Undergoing General Anesthesia. CURRENT DRUG METABOLISM, 23(14), 1156-1161.
DOI WoS2 Europe PMC2
2023 El-Sadoni, M., Al Shboul, S., Alhesa, A., Shahin, N. A., Alsharaiah, E., Ismail, M. A., . . . Saleh, T. (2023). A three-marker signature identifies senescence in human breast cancer exposed to neoadjuvant chemotherapy. CANCER CHEMOTHERAPY AND PHARMACOLOGY, 91(4), 345-360.
DOI WoS19 Europe PMC20
2023 Asad, M. M., Abdelhafez, R. S., Barham, R., Abdaljaleel, M., Alkurdi, B., Al-Hadidi, S., . . . Ababneh, N. A. (2023). Three-dimensional cultures of gingival fibroblasts on fibrin-based scaffolds for gingival augmentation: A proof-of-concept study. ARCHIVES OF ORAL BIOLOGY, 154, 8 pages.
DOI WoS2 Europe PMC1
2023 Abu-Humaidan, A., Ismail, M. A., Barham, R., Ahmad, F. M., Ababneh, N. A., & Saleh, T. (2023). Therapy induced senescence in cancer cell lines affects complement activation and complement regulatory proteins expression. IMMUNOBIOLOGY, 228(5), 93.
DOI
2023 Al Shboul, S., El-Sadoni, M., Alhesa, A., Abu Shahin, N., Abuquteish, D., Abu Al Karsaneh, O., . . . Saleh, T. (2023). NOXA expression is downregulated in human breast cancer undergoing incomplete pathological response and senescence after neoadjuvant chemotherapy. Scientific Reports, 13(1), 1-12.
DOI WoS17 Europe PMC13
2023 Niemi, M. E. K., Karjalainen, J., Liao, R. G., Neale, B. M., Daly, M., Ganna, A., . . . Sedaghati-Khayat, B. (2023). Erratum to: Mapping the human genetic architecture of COVID-19 (Nature, (2021), 600, 7889, (472-477), 10.1038/s41586-021-03767-x). Nature, 621(7977), E7-E26.
DOI Scopus70 WoS85 Europe PMC90
2022 Ababneh, N. A., Barham, R., Al-Kurdi, B., Ali, D., Al Hadidi, S., Ismail, M. A., . . . Awidi, A. (2022). Generation of a human induced pluripotent stem cell (iPSC) line (JUCTCi019-A) from a patient with Charcot-Marie-Tooth disease type 2A2 (CMT2A2) due to a heterozygous missense substitution c.2119C &gt; T (p. Arg707Trp) in MFN2 gene. STEM CELL RESEARCH, 62, 5 pages.
DOI WoS3 Europe PMC3
2021 Sweidan, N., Esawi, E., Ismail, M., & Alshaer, W. (2021). Anticancer Cardenolides from the aerial parts of Calortopis procera. Zeitschrift Fur Naturforschung Section C Journal of Biosciences, 76(5), 243-250.
DOI Scopus4 WoS4 Europe PMC3
2020 Odeh, F., Nsairat, H., Alshaer, W., Ismail, M. A., Esawi, E., Qaqish, B., . . . Ismail, S. I. (2020). Aptamers chemistry: Chemical modifications and conjugation strategies. Molecules, 25(1), 51 pages.
DOI Scopus329 WoS303 Europe PMC220
- Abdo, E., Ismail, M. A., Al Hadidi, S., Al-Mrahleh, M., Saleh, T., Zihlif, M., & Ababneh, N. A. (2025). Effect of cytotoxic CD8+ T-cells secretory proteins on hypoxic pancreatic cancer cells. PLOS ONE, 20(1), e0311615.
DOI

Year Citation
2022 Nsairat, H., Alshaer, W., Mahmoud, I. S., Ismail, M. A., Esawi, E., Alsotari, S., & Ismail, S. I. (2022). Aptamers in Theranostic Bionanomaterials. In Bionanotechnology Next Generation Therapeutic Tools (pp. 130-158). BENTHAM SCIENCE PUBLISHERS.
DOI Scopus1

Year Citation
2025 Hussein, S. A., Ababneh, N. A., Tarawneh, N., Ismail, M. A., Awidi, A., & Abdalla, S. (2025). Antitumor Effects of Quercetin and Luteolin Are Mediated by Up-Regulation of P-Erk, C-Myc, and the Upstream Gper in A375 Melanoma Cell Line.
DOI

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