Megan Penno

Teaching Strengths

National Research Training Leadership
Multidisciplinary Research Education
Mentorship of Early Career Researchers
Research Capacity Building
HDR Supervision and Research Training

Dr Megan Penno

Grant-Funded Researcher (C)

School of Medicine

College of Health


Dr Megan Penno (BSc Hons PhD, University of Melbourne) is the Chief Operating Officer for the Environmental Determinants of Islet Autoimmunity (ENDIA) study and Grant-Funded Research at Adelaide University, Australia. ENDIA is the first study in the world to explore how environmental exposures from pregnancy through early life may contribute to, or protect against, the development of childhood type 1 diabetes. 

Dr Megan Penno has provided leadership for the ENDIA study since its establishment in 2012 and has played a pivotal role in the development of Australia's largest pregnancy–birth cohort investigating type 1 diabetes. She led the design of ENDIA's sample and data collection frameworks, authored the study protocol, and has contributed to the strategic growth of the cohort and its associated biobank and data resources. Dr Penno has secured and contributed to successful national and international funding applications exceeding AU$32 million over the past five years and provides leadership in research governance, infrastructure development, and multidisciplinary collaborations. Her research focuses on biomarker discovery and the translation of omics approaches to disease prediction and risk stratification.

For more information about the ENDIA study please visit our website at http://www.endia.org.au

ENDIA team

Date Position Institution name
2019 - ongoing Grant Funded Researcher University of Adelaide
2015 - 2018 Academic Research Clinical Coordinator University of Adelaide
2012 - 2014 Senior Clinical Research Coordinator University of Adelaide
2007 - 2012 Post-doctoral fellow University of Adelaide
2006 - 2006 Grant Funded Scientist Hanson Institute

Date Type Title Institution Name Country Amount
2022 Research Award Faculty of Health and Medical Sciences Executive Dean's Award for Research Excellence (mid-career) The University of Adelaide Australia -
2020 Award IDS 17th Congress High-Scoring Abstracts Award Immunology of Diabetes Society China -
2018 Award CUDOS 2018 Conference poster prize Sidra Medicine Qatar -
2018 Nomination JDRF Australia & Macquarie Group Foundation Future Leader Program JDRF Australia Australia -
2014 Award Robinson Research Institute Travel Award University of Adelaide, Robinson Research Institute Australia $1,100
2011 Award Research Career Development Network (RCDN) Workshop Award University of Adelaide, School of Molecular and Biomedical Sciences Australia $2,000
2008 Award Overseas Conference Scheme Travel Award University of Adelaide, Faculty of Science Australia $2,000
2004 Award American Society for Biochemistry and Molecular Biology Graduate Travel Award The American Society for Biochemistry and Molecular Biology United States US$1,000
2004 Award Dawson Bursary The University of Melbourne Australia $6,000
2004 Award School of Botany Travel Scholarship The University of Melbourne, School of Botany Australia -
2003 Scholarship Sir John and Lady Higgins Research Scholarship The University of Melbourne Australia $70,000

Language Competency
English Can read, write, speak, understand spoken and peer review

Date Institution name Country Title
2003 - 2007 University of Melbourne Australia PhD
1999 - 2002 University of Melbourne Australia BSc (Honours)

Year Citation
2026 Thomson, R. L., Martin, G., McGorm, K. J., Spelman, T., Craig, M. E., Penno, M. A. S., . . . ENDIA Study Group. (2026). Perceived stress in mothers of children with and without islet and coeliac autoimmunity in the ENDIA study. Diabetologia, 69(2), 343-349.
DOI Scopus1 WoS1
2026 Couper, J. J., Oakey, H., Penno, M. A. S., Wentworth, J. M., Watson, K., Brown, J. D., . . . ENDIA Study Group. (2026). Evolution of islet autoantibodies in the Environmental Determinants of Islet Autoimmunity (ENDIA) prospective cohort. Diabetologia, 69(3), 631-642.
DOI Scopus1
2026 Thomson, R. L., Martin, G., Brown, J. D., Oakey, H., Ashwood, P., Penno, M. A. S., . . . ENDIA Study Group*. (2026). A Comparison of Diet and Exercise During Pregnancy in Women With and Without Type 1 Diabetes Followed in the Environmental Determinants of Islet Autoimmunity (ENDIA) Study. Diabetes Care, 49(3), 471-477.
DOI
2026 Delgado-Corrales, B., Fingerhut, L., Leung, P., Yau, C. S. A., Foster, C. S. P., Ward, E. J., . . . ENDIA Study Group*. (2026). Distinct Enterovirus Antigen Landscape in Children With Islet Autoimmunity. Diabetes, 75(4), 738-747.
DOI Scopus2 WoS2
2026 Price, S. A. L., Chee, M., Earnest, A., Thomson, R. L., Penno, M. A. S., Couper, J. J., . . . Jones, T. (2026). Continuous Glucose Monitoring in Pregnant Women with Type 1 Diabetes: Outcomes of a Population-Based Real-World Study. Diabetes Technology and Therapeutics, 1-9.
DOI
2026 Roth-Schulze, A. J., Ngui, K. M., Martin, G., Ashwood, P., Thomson, R. L., Zozaya-Valdes, E., . . . ENDIA Study Group. (2026). Delayed maturation of the milk microbiome in women with type 1 diabetes. Diabetologia, 1-14.
DOI
2026 Tully, A. S., Binkowski, S. K., Nevin, B. R., Penno, M. A. S., Anderson, A. J., Craig, M. E., . . . Haynes, A. (2026). Understanding parents' perspectives of repeated blinded continuous glucose monitoring in children with early-stage type 1 diabetes and an affected first-degree relative. Diabetic Medicine, 9 pages.
DOI
2025 Walker, G. J., Mallitt, K. -A., Craig, M. E., Ashwood, P., Barry, S. C., Brown, J. D., . . . ENDIA Study Group. (2025). SARS-CoV-2 Infection and Childhood Islet Autoimmunity. JAMA Pediatrics, 179(5), 568-570.
DOI Scopus6 WoS4 Europe PMC3
2025 Roth-Schulze, A. J., Bandala-Sanchez, E., Ngui, K. M., Naselli, G., Oakey, H., Ashwood, P., . . . ENDIA Study Group. (2025). Adverse pregnancy outcomes in women with type 1 diabetes are associated with multiple alterations in the vaginal microbiome. Diabetologia, 68(11), 2552-2566.
DOI Scopus3 WoS4 Europe PMC3
2025 Haynes, A., Smith, G. J., Tully, A., Mellor, B. R., Penno, M. A. S., Craig, M. E., . . . Davis, E. A. (2025). Longitudinal Continuous Glucose Monitoring Study in Young Children With Presymptomatic Type 1 Diabetes Followed in the Environmental Determinants of Islet Autoimmunity (ENDIA) At-Risk Cohort Study. Diabetes Care, 48(10), 1812-1817.
DOI Scopus1 WoS1 Europe PMC1
2025 Harrison, L. C., Allnutt, T. R., Hanieh, S., Roth-Schulze, A. J., Ngui, K. M., Stone, N. L., . . . Ashwood, P. (2025). Indigenous infants in remote Australia retain an ancestral gut microbiome despite encroaching Westernization. Nature Communications, 16(1), 15 pages.
DOI Scopus2 WoS2 Europe PMC1
2024 Thomson, R. L., Oakey, H., Haynes, A., Craig, M. E., Harrison, L. C., Wentworth, J. M., . . . Couper, J. J. (2024). Environmental Determinants of Islet Autoimmunity (ENDIA) longitudinal prospective pregnancy to childhood cohort study of Australian children at risk of type 1 diabetes: parental demographics and birth information. BMJ Open Diabetes Research & Care, 12(4), e004130-1-e004130-13.
DOI Scopus7 WoS8 Europe PMC7
2024 Haynes, A., Tully, A., Smith, G. J., Penno, M. A. S., Craig, M. E., Wentworth, J. M., . . . ENDIA Study Group. (2024). Early Dysglycemia Is Detectable Using Continuous Glucose Monitoring in Very Young Children at Risk of Type 1 Diabetes.. Diabetes care, 47(10), 1750-1756.
DOI Scopus17 WoS16 Europe PMC12
2024 Thomson, R. L., Brown, J. D., Oakey, H., Palmer, K., Ashwood, P., Penno, M. A. S., . . . ENDIA Study Group. (2024). Dietary patterns during pregnancy and maternal and birth outcomes in women with type 1 diabetes: the Environmental Determinants of Islet Autoimmunity (ENDIA) study. Diabetologia, 67(11), 2420-2432.
DOI Scopus7 WoS6 Europe PMC5
2024 Roberts, A. G., Tully, A. S., Binkowski, S. K., Bebbington, K. R., Penno, M. A. S., Anderson, A. J., . . . Haynes, A. (2024). Parental experiences of using continuous glucose monitoring in their young children with early-stage type 1 diabetes: a qualitative interview study. Frontiers in Clinical Diabetes and Healthcare, 5, 7 pages.
DOI Scopus2 WoS3
2023 McGorm, K. J., Brown, J. D., Thomson, R. L., Oakey, H., Moore, B., Hendry, A., . . . Penno, M. A. S. (2023). A Long-Term Evaluation of Facebook for Recruitment and Retention in the ENDIA Type 1 Diabetes Pregnancy-Birth Cohort Study. Journal of Diabetes Science and Technology, 17(3), 696-704.
DOI Scopus4 WoS3 Europe PMC4
2023 McGorm, K. J., Brown, J. D., Roberts, A. G., Greenbank, S., Brasacchio, D., Sawyer, A. C. P., . . . Penno, M. A. S. (2023). Experiences of Caregivers and At-Risk Children Enrolled in a Prospective Pregnancy-Birth Cohort Study into the Causes of Type 1 Diabetes: The ENDIA Study. Children, 10(4), 637.
DOI Scopus4 WoS4 Europe PMC3
2023 Oakey, H., Giles, L. C., Thomson, R. L., Lê Cao, K. -A., Ashwood, P., Brown, J. D., . . . ENDIA Study Group. (2023). Protocol for a nested case-control study design for omics investigations in the Environmental Determinants of Islet Autoimmunity cohort. Annals of Medicine, 55(1), 1-14.
DOI Scopus9 WoS9 Europe PMC9
2023 Harrison, L. C., Bandala-Sanchez, E., Oakey, H., Colman, P. G., Watson, K., Kim, K. W., . . . ENDIA Study Group. (2023). A surge in serum mucosal cytokines associated with seroconversion in children at risk for type 1 diabetes. Journal of Diabetes Investigation, 14(9), 1092-1100.
DOI WoS1
2023 Oakey, H., Giles, L. C., Thomson, R. L., Le Cao, K. -A., Ashwood, P., Brown, J. D., . . . ENDIA, S. G. (2023). Protocol for a nested case- control study design for omics investigations in the environmental determinants of islet autoimmunity cohort (vol 55, 2198255, 2023). ANNALS OF MEDICINE, 55(1), 1 page.
DOI
2022 Bandala-Sanchez, E., Roth-Schulze, A. J., Oakey, H., Penno, M. A. S., Bediaga, N. G., Naselli, G., . . . ENDIA Study Group. (2022). Women with type 1 diabetes exhibit a progressive increase in gut Saccharomyces cerevisiae in pregnancy associated with evidence of gut inflammation.. Diabetes research and clinical practice, 184, 1-23.
DOI Scopus11 WoS11 Europe PMC11
2022 Hall, M., Oakey, H., Penno, M. A. S., McGorm, K., Anderson, A. J., Ashwood, P., . . . Cavenett, L. (2022). Mental Health During Late Pregnancy and Postpartum in Mothers With and Without Type 1 Diabetes: The ENDIA Study. Diabetes Care, 45(5), 1082-1090.
DOI Scopus4 WoS4 Europe PMC6
2021 Harbison, J. E., Thomson, R. L., Wentworth, J. M., Louise, J., Roth‐Schulze, A., Battersby, R. J., . . . Couper, J. J. (2021). Associations between diet, the gut microbiome and short chain fatty acids in youth with islet autoimmunity and type 1 diabetes. Pediatric Diabetes, 22(3), 425-433.
DOI Scopus11 WoS10 Europe PMC10
2021 Penno, M. A., Anderson, A. J., Thomson, R. L., McGorm, K., Barry, S. C., Colman, P. G., . . . ENDIA Study Group. (2021). Evaluation of protocol amendments to the Environmental Determinants of Islet Autoimmunity (ENDIA) study during the COVID-19 pandemic. Diabetic Medicine, 38(11), e14638-1-e14638-4.
DOI Scopus3 WoS2 Europe PMC3
2021 Roth-Schulze, A. J., Penno, M. A. S., Ngui, K. M., Oakey, H., Bandala-Sanchez, E., Smith, A. D., . . . Harrison, L. C. (2021). Type 1 diabetes in pregnancy is associated with distinct changes in the composition and function of the gut microbiome. Microbiome, 9(1), 167-1-167-21.
DOI Scopus37 WoS36 Europe PMC36
2021 Hope, C. M., Huynh, D., Wong, Y. Y., Oakey, H., Perkins, G. B., Nguyen, T., . . . Barry, S. C. (2021). Optimization of blood handling and peripheral blood mononuclear cell cryopreservation of low cell number samples. International Journal of Molecular Sciences, 22(17), 9129-1-9129-19.
DOI Scopus22 WoS20 Europe PMC23
2020 Augustine, P., Gent, R., Louise, J., Taranto, M., Penno, M., Linke, R., . . . ENDIA Study Group. (2020). Pancreas size and exocrine function is decreased in young children with recent-onset Type 1 diabetes. Diabetic Medicine, 37(8), 1340-1343.
DOI Scopus24 WoS21 Europe PMC21
2020 Begum, M., Pilkington, R. M., Chittleborough, C. R., Lynch, J. W., Penno, M., & Smithers, L. G. (2020). Effect of maternal smoking during pregnancy on childhood type 1 diabetes: a whole-of-population study. Diabetologia, 63(6), 1162-1173.
DOI Scopus9 WoS8 Europe PMC7
2020 Penno, M. A., Oakey, H., Augustine, P., Taranto, M., Barry, S. C., Colman, P. G., . . . Couper, J. J. (2020). Changes in pancreatic exocrine function in young at-risk children followed to islet autoimmunity and type 1 diabetes in the ENDIA study. Pediatric Diabetes, 21(6), 945-949.
DOI Scopus12 WoS10 Europe PMC12
2020 Begum, M., Chittleborough, C., Pilkington, R., Mittinty, M., Lynch, J., Penno, M., & Smithers, L. (2020). Educational outcomes among children with type 1 diabetes: whole-of-population linked-data study. Pediatric Diabetes, 21(7), 1353-1361.
DOI Scopus14 WoS13 Europe PMC12
2020 Begum, M., Chittleborough, C., Pilkington, R., Mittinty, M., Lynch, J., Penno, M., & Smithers, L. (2020). Incidence of type 1 diabetes by socio-demographic characteristics among South Australian children: Whole-of-population study. Journal of Paediatrics and Child Health, 56(12), 1985-1958.
DOI Scopus4 WoS5 Europe PMC5
2019 Ziegler, A., Hoffmann, G. F., Hasford, J., Elding Larsson, H., Danne, T., Berner, R., . . . Bonifacio, E. (2019). Screening for asymptomatic β-cell autoimmunity in young children. Lancet Child and Adolescent Health, 3(5), 288-290.
DOI Scopus11 WoS11 Europe PMC10
2019 Wook Kim, K., Allen, D. W., Briese, T., Couper, J. J., Barry, S. C., Colman, P. G., . . . ENDIA Study Group. (2019). Distinct gut virome profile of pregnant women with type 1 diabetes in the ENDIA study. Open forum infectious diseases, 6(2), 1-8.
DOI Scopus44 WoS40 Europe PMC37
2019 Harbison, J. E., Roth-Schulze, A. J., Giles, L. C., Tran, C. D., Ngui, K. M., Penno, M. A., . . . Couper, J. J. (2019). Gut microbiome dysbiosis and increased intestinal permeability in children with islet autoimmunity and type 1 diabetes: a prospective cohort study. Pediatric Diabetes, 20(5), 574-583.
DOI Scopus132 WoS114 Europe PMC109
2019 Craig, M. E., Kim, K. W., Isaacs, S. R., Penno, M. A., Hamilton-Williams, E. E., Couper, J. J., & Rawlinson, W. D. (2019). Early-life factors contributing to type 1 diabetes. Diabetologia, 62(10), 1823-1834.
DOI Scopus96 WoS86 Europe PMC79
2019 Begum, M., Pilkington, R., Chittleborough, C., Lynch, J., Penno, M., & Smithers, L. (2019). Caesarean section and risk of type 1 diabetes: whole-of-population study. Diabetic medicine : a journal of the British Diabetic Association, 36(12), 1686-1693.
DOI Scopus18 WoS18 Europe PMC16
2019 Kedzior, S., Bianco-Miotto, T., Breen, J., Diener, K. R., Donnelley, M. W., Dunning, K. R., . . . Rumbold, A. R. (2019). It takes a community to conceive: an analysis of the scope, nature and accuracy of online sources of health information for couples trying to conceive. Reproductive Biomedicine and Society Online, 9, 48-63.
DOI Scopus12 Europe PMC13
2019 Kim, K. W., Allen, D. W., Briese, T., Couper, J. J., Barry, S. C., Colman, P. G., . . . ENDIA STUDY GROUP. (2019). Higher frequency of vertebrate-infecting viruses in the gut of infants born to mothers with type 1 diabetes. Pediatric Diabetes, 21(2), 271-279.
DOI Scopus13 WoS11 Europe PMC12
2018 Penington, J., Penno, M., Ngui, K., Ajami, N., Roth-Schulze, A., Wilcox, S., . . . Vuillermin, P. (2018). Influence of fecal collection conditions and 16S rRNA gene sequencing at two centers on human gut microbiota analysis. Scientific Reports, 8(1), 4386-1-4386-10.
DOI Scopus50 WoS48 Europe PMC43
2018 Wentworth, J. M., Bediaga, N. G., Penno, M. A., Bandala-Sanchez, E., Kanojia, K. N., Kouremenos, K. A., . . . ENDIA, S. G. (2018). Minimal variation of the plasma lipidome after delayed processing of neonatal cord blood. Metabolomics, 14(10), 130-1-130-3.
DOI Scopus1 WoS1 Europe PMC1
2018 Penington, J. S., Penno, M., Ngui, K., Ajami, N., Roth-Schulze, A., Wilcox, S., . . . Giles, L. (2018). Influence of fecal collection conditions and 16S rRNA gene sequencing protocols at two centers on human gut microbiota analysis. Scientific Reports, 8, 10 pages.
DOI
2017 Phillips, J., Couper, J., Penno, M., & Harrison, L. (2017). Type 1 diabetes: a disease of developmental origins. Pediatric Diabetes, 18(6), 417-421.
DOI Scopus11 WoS11 Europe PMC9
2016 Penno, M. A. S., Thomson, R. L., & Couper, J. J. (2016). Bunbury to Bundaberg, Darwin to Dover: establishing a successful Regional Participation Program for the ENDIA type 1 diabetes cohort study. The Medical journal of Australia, 205(10), 486-486.e1.
DOI Scopus6 WoS6 Europe PMC6
2014 Humphries, J., Penno, M., Weiland, F., Klingler-Hoffmann, M., Zuber, A., Boussioutas, A., . . . Hoffmann, P. (2014). Identification and validation of novel candidate protein biomarkers for the detection of human gastric cancer. Biochimica et Biophysica Acta - Proteins and Proteomics, 1844(5), 1051-1058.
DOI Scopus54 WoS52 Europe PMC41
2013 Penno, M., Couper, J., Craig, M., Colman, P., Rawlinson, W., Cotterill, A., . . . Wentworth, J. (2013). Environmental determinants of islet autoimmunity (ENDIA): a pregnancy to early life cohort study in children at-risk of type 1 diabetes. BMC Pediatrics, 13(1), 1-15.
DOI Scopus79 WoS72 Europe PMC63
2013 Sciacca, B., François, A., Klingler-Hoffmann, M., Brazzatti, J., Penno, M., Hoffmann, P., & Monro, T. (2013). Radiative-surface plasmon resonance for the detection of apolipoprotein E in medical diagnostics applications. Nanomedicine: Nanotechnology, Biology & Medicine, 9(4), 550-557.
DOI Scopus54 WoS38 Europe PMC14
2012 Penno, M., Klingler-Hoffmann, M., Brazzatti, J., Boussioutas, A., Putoczki, T., Ernst, M., & Hoffmann, P. (2012). 2D-DIGE analysis of sera from transgenic mouse models reveals novel candidate protein biomarkers for human gastric cancer. Journal of Proteomics, 77, 40-58.
DOI Scopus27 WoS26 Europe PMC21
2012 Penno, M., Colegate, S., Michalski, W., & Hoffmann, P. (2012). Detection and measurement of carbohydrate deficient transferrin in serum using immuno-capture mass spectrometry: Diagnostic applications for annual ryegrass toxicity and corynetoxin exposure. Research in Veterinary Science, 93(2), 611-617.
DOI Scopus4 WoS4 Europe PMC2
2012 Ho, Y., Penno, M., Perugini, M., Lewis, I., & Hoffmann, P. (2012). Evaluating the efficacy of subcellular fractionation of blast cells using live cell labeling and 2D DIGE. Methods in molecular biology, 854, 319-332.
DOI
2012 Penno, M., Ernst, M., & Hoffmann, P. (2012). Comparative 2D DIGE analysis of the depleted serum proteome for biomarker discovery. Methods in molecular biology, 854, 207-220.
DOI Scopus3 Europe PMC4
2012 Kopetz, V., Penno, M., Hoffmann, P., Wilson, D., & Beltrame, J. (2012). Potential mechanisms of the acute coronary syndrome presentation in patients with the coronary slow flow phenomenon - Insight from a plasma proteomic approach. International Journal of Cardiology, 156(1), 84-91.
DOI Scopus40 WoS34 Europe PMC28
2009 Penno, M., Ernst, M., & Hoffmann, P. (2009). Optimal preparation methods for automated matrix-assisted laser desorption/ionization time-of-flight mass spectrometry profiling of low molecular weight proteins and peptides. Rapid Communications in Mass Spectrometry, 23(17), 2656-2662.
DOI Scopus24 WoS24 Europe PMC23
2009 Penno, M., Bacic, A., Colegate, S., Hoffmann, P., & Michalski, W. (2009). Identifying candidate serum biomarkers of exposure to tunicamycins in rats using two-dimensional electrophoresis. Journal of Proteome Research, 8(6), 2812-2826.
DOI Scopus4 WoS4 Europe PMC4
2006 Aslani, M., Pascoe, I., Kowalski, M., Michalewicz, A., Penno, M., & Colegate, S. (2006). In vitro detection of hepatocytotoxic metabolites from Drechslera biseptata: a contributing factor to acute bovine liver disease?. Australian Journal of Experimental Agriculture, 46(5), 599-604.
DOI WoS7

Year Citation
2007 Allen, J. G., Retallick, M., Kowalski, M., Colegate, S. M., Speijers, E. J., Doran, T., . . . others. (2007). A study of the bioequivalence of corynetoxins and tunicamycins: the effect of these toxins on the viability and morphology of rat hepatocytes in tissue culture.. In Unknown Book (pp. 504-510). CABI.
2007 Retallick, M. A. S., Colegate, S. M., Michalski, W. P., Panter, K. E., Wierenga, T. L., Pfister, J. A., & others. (2007). A toxicoproteomic approach to understanding annual ryegrass toxicity.. In Unknown Book (pp. 230-234). CABI.

Year Citation
2026 Zaitouny, A., Krishnan, A., Chee, J., Smith, G., Tully, A., Penno, M., . . . Haynes, A. (2026). INTEGRATING SYMBOLIC STATISTICAL AND MACHINE LEARNING TO ANALYSE CGM DATA FROM YOUNG CHILDREN WITH PRE-SYMPTOMATIC TYPE 1 DIABETES. In DIABETES TECHNOLOGY & THERAPEUTICS Vol. 28 (pp. 64S-65S). SAGE PUBLICATIONS INC.
2025 Hall, M., Brown, J., Rankin, W., Penno, M., Colman, P., Huynh, D., . . . Couper, J. (2025). Longitudinal changes in exocrine function in early life in children progressing to islet autoimmunity: the ENDIA Study. In HORMONE RESEARCH IN PAEDIATRICS Vol. 98 (pp. 40-41). KARGER.
2024 Walker, G., Mallitt, K. -A., Sevendal, A., Ward, E., Caguicla, J., Naing, Z., . . . Rawlinson, W. (2024). No increased risk of islet autoimmunity following SARS-CoV-2 infection in ENDIA children. In HORMONE RESEARCH IN PAEDIATRICS Vol. 97 (pp. 198). KARGER.
2023 Thomson, R. L., Brown, J. D., Oakey, H., Penno, M. A. S., Battersby, R., Ashwood, P., . . . Couper, J. J. (2023). A comparison of lifestyle during pregnancy against Australian recommendations of women with and without type 1 diabetes from the Environmental Determinants of Islet Autoimmunity study. In PROCEEDINGS OF THE NUTRITION SOCIETY Vol. 82 (pp. 1 page). CAMBRIDGE UNIV PRESS.
DOI WoS1
2022 Haynes, A., Tully, A., Smith, G. J., Penno, M. A. S., Craig, M. E., Wentworth, J. M., . . . Davis, E. A. (2022). Continuous glucose monitoring identifies early dysglycaemia in very young children at risk of type 1 diabetes being followed in the Australian ENDIA pregnancy cohort study. In DIABETOLOGIA Vol. 65 (pp. S173-S174). SWEDEN, Stockholm: SPRINGER.
2019 Haynes, A., Giles, L., Penno, M., Thomson, R., McGorm, K., Colman, P., . . . ENDIA Study Group. (2019). Cohort profile: the Australia-wide environmental determinants of islet autoimmunity (ENDIA) study. In Diabetologia Vol. 62 (pp. S139-S140). Barcelona, Spain: Springer.
2019 Begum, M., Pilkington, R. M., Chittleborough, C. R., Lynch, J. W., Penno, M., & Smithers, L. G. (2019). MATERNAL SMOKING DURING PREGNANCY AND RISK OF TYPE 1 DIABETES: WHOLE-OF-POPULATION STUDY. In JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH Vol. 73 (pp. A36-A37). BMJ PUBLISHING GROUP.
DOI
2019 Begum, M., Chittleborough, C. R., Pilkington, R. M., Mittinty, M., Lynch, J. W., Penno, M., & Smithers, L. G. (2019). EDUCATIONAL OUTCOMES AMONG CHILDREN WITH TYPE 1 DIABETES: WHOLE-OF-POPULATION STUDY. In JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH Vol. 73 (pp. A55-A56). BMJ PUBLISHING GROUP.
DOI
2018 Harbison, J. E., Roth-Schulze, A. J., Barry, S. C., Tran, C. D., Ngui, K., Penno, M. A., . . . Couper, J. (2018). Gut Microbiome Dysbiosis and Increased Intestinal Permeability in Australian Children with Islet Autoimmunity and Type 1 Diabetes. In DIABETES Vol. 67 (pp. 2 pages). Orlando, FL: AMER DIABETES ASSOC.
DOI WoS2
2017 Thomson, R., Penno, M. A., Battersby, R., & Couper, J. (2017). Are pregnant women meeting the Australian dietary guidelines? A comparison of women with and without Type 1 diabetes. In Journal of Nutrition and Intermediary Metabolism Vol. 8 (pp. 76-77). Melbourne: Elsevier.
DOI
2017 Kim, K. W., Allen, D. W., Briese, T., Pang, C. N., Jain, K., Horton, J. L., . . . Craig, M. E. (2017). Gut Virome Dynamics during Pregnancy in Mothers with Type 1 Diabetes. In Abstracts of the 77th Scientific Sessions of the American Diabetes Association, as published in Diabetes Vol. 66 (pp. LB192). San Diego, CA: American Diabetes Association.
2012 Sciacca, B., François, A., Penno, M., Brazzatti, J., Klingler-Hoffmann, M., Hoffmann, P., & Monro, T. (2012). Radiative-SPR platform for the detection of apolipoprotein E for use in medical diagnostics. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE Vol. 8234 (pp. 1-8). US: SPIE.
DOI Scopus1
2011 François, A., Courtney, J., Penno, M., Hoffmann, P., & Monro, T. (2011). A novel optical-fiber based surface plasmon resonance sensing architecture and its application to gastric cancer diagnostics. In W. Bock, J. Albert, & X. Bao (Eds.), Proceedings of SPIE Vol. 7753 (pp. 1-4). Ottawa, Canada: SPIE.
DOI Scopus3 WoS1
2008 Kopetz, V., Penno, M., Hoffmann, P., & Beltrame, J. (2008). Plasma Proteomic Investigations in the Coronary Slow Flow Phenomenon: Exploring Mechanisms for the Acute Coronary Syndrome Presentation. In Heart, Lung and Circulation Vol. 17 (pp. S235). Elsevier BV.
DOI

Year Citation
2015 Hoffmann, P., Penno, M., & Ernst, M. R. W. (2015). BIOMARKERS FOR GASTRIC CANCER AND USES THEREOF.

Since 2013, Dr Penno has demonstrated sustained success in attracting nationally and internationally competitive research funding to support type 1 diabetes research, cohort infrastructure and translational discovery programs. 

As Chief Investigator, associate investigator, and project manager, she has secured and contributed to grants exceeding AU$60 million from major national and international funding bodies. 

Funding Organisation Application Title (ID) Amount (AUD) Funding Application Role Source First Funded Years Administering Institution
Breakthrough T1D Are there shared mechanisms in naturally acquired and therapeutically induced protection from type 1 diabetes and are they shaped by autoreactive T cell pools and TCR clonality? (2-SRA-2027-2033-M-N) $1,099,974.50 Chief Investigator Domestic 2026 2 Adelaide University
Breakthrough T1D Designing and delivering optimal care of early type 1 diabetes in Australia (AU arm) (3-SRA-2026-1833-M-N) $1,605,811 Chief Investigator International 2026 3 Adelaide University
Breakthrough T1D Australia Designing and delivering optimal care of early type 1 diabetes in Australia (US arm) (3-SRA-2026-1949-M-B) $2,774,154 Chief Investigator Domestic 2026 3 Adelaide University
Breakthrough T1D Australia ENDIA 2026 (201313631) $2,000,000 Chief Investigator Domestic 2026 1 Adelaide University
Channel 7 Children's Research Foundation Antibody fingerprinting to solve an unsolved crime (50119150) $99,691 Chief Investigator Domestic 2026 1 Flinders University
Medical Research Future Fund Polygenic Risk-Stratified Population-wide Screening for Type 1 Diabetes in Children (2025/MRF2044979) $985,164 Associate investigator Domestic 2025 2 University of Sydney
Breakthrough T1D Experiences of children with early-stage T1D and their families (2-SRA-2025-1649-M-B) $285,000 Chief Investigator International 2025 2 University of Adelaide
Breakthrough T1D Australia The ENDIA 4000 Genomes Project (1-SRA-2025-1703-M-B) $260,000 Chief Investigator (first named) Domestic 2025 1 University of Adelaide
National Health and Medical Research Council (European Union Collaborative Research Grants) Characterising viruses that promote the development of type 1 diabetes (2023/GNT2032781) $531,959 Chief Investigator Domestic 2024 4 University of NSW
National Institute of Health High-resolution, virome-wide infection analysis in T1D birth cohorts (R01DK140795-01) $5,189,862 Associate Investigator International 2024 3 Translational Genomics Research Institute, USA
Breakthrough T1D Using Multi-omics to turn islet autoimmunity driver genes into therapies (3-SRA-2024-1531-S-B) $599,502 Chief Investigator International 2024 3 University of Adelaide
Breakthrough T1D Investigating the utility of urine C-peptide in early-stage T1D (1-SRA-2024-1582-S-B) $142,900 Chief Investigator International 2024 2 University of Adelaide
Breakthrough T1D Expanded data mining of accumulated functional genomics data (3-SRA-2024-1532-S-B) $668,533 Chief Investigator (first named) International 2024 3 University of Adelaide
JDRF Australia, JDRF International, and The Leona M. and Harry B. Helmsley Charitable Trust Deep milk:  multi-omics to resolve the role of human breastmilk in T1D risk (2-SRA-2024-1513-M-N) $795,974 Chief Investigator Domestic 2024 2 Baker Heart and Diabetes Institute
JDRF Australia and The Leona M. and Harry B. Helmsley Charitable Trust Partnership Metabolism in pregnancy and pancreatic beta cell function in offspring (2-SRA-2024-1515-M-N) $792,694 Chief Investigator Domestic 2024 2 University of Leicester, UK
JDRF Australia and The Leona M. and Harry B. Helmsley Charitable Trust Partnership Establishing immune, endocrine, and exocrine signatures of type 1 diabetes (2-SRA-2024-1514-M-N) $226,897 Chief Investigator Domestic 2024 2 University of Florida, USA
JDRF Australia and The Leona M. and Harry B. Helmsley Charitable Trust Partnership Familial Sharing of Gut Microbes and Mobile Genetic Elements (2-SRA-2024-1511-M-N) $401,066 Chief Investigator Domestic 2024 2 University of Helsinki, Finland
JDRF Australia and The Leona M. and Harry B. Helmsley Charitable Trust Partnership Epigenomic Mechanisms of the Maternal Protection in Type 1 Diabetes (2-SRA-2024-1512-M-N) $799,999 Chief Investigator Domestic 2024 2 University of Colorado, USA
Rio Tinto Children's Diabetes Centre Global Centre of Excellence Investigating the urinary proteome as a source of risk-associated biomarkers (FND005027) $19,901 Chief Investigator (first named) Domestic 2024 1 University of Adelaide
The Leona M. and Harry B. Helmsley Charitable Trust Immune responses to intestinal bacteria associated with T1D risk and progression (201310593) $742,072 Associate investigator International 2024 2 Hospital for Sick Kids, Canada
The Leona M. and Harry B. Helmsley Charitable Trust Epigenomic biomarkers of the incomplete maternal protection in type 1 diabetes (244115) $1,508,166 Associate investigator International 2024 1 University of Colorado, USA
National Health and Medical Research Council (Ideas Grants) Pregnancy and early life virome dynamics: contribution to chronic diseases (2022/GNT2021404) $1,490,553 Associate investigator Domestic 2023 3 University of NSW
Croatian Science Foundation (Hrvatske zaklade za znanost) Glycosylation of complement component C3 in development of T1D and autoimmunity (IP-2022-10-3983) $309,285 Chief Investigator International 2023 4 University of Zagreb, Croatia
JDRF International Enhancing risk prediction and stratification through multi-omics profiling (5-CDA-2023-1332-S-B) $1,428,569 Chief Investigator International 2023 5 University of NSW
JDRF Australia ENDIA Follow Up 2023 - 2025 (3-SRA-2023-1374-M-N) $8,977,647 Chief Investigator Domestic 2023 3 University of Adelaide
The Leona M. and Harry B. Helmsley Charitable Trust Pancreatic exocrine function and progression to type 1 diabetes in young children (R-2301-06581) $489,252 Chief Investigator International 2023 3 University of Western Australia
National Health and Medical Research Council (Ideas Grants) A microRNA NanoChip Technology for Predicting Childhood Type 1 Diabetes Risk (2021/GNT2011557) $399,659 Chief Investigator Domestic 2022 2 University of Western Sydney
The Leona M. and Harry B. Helmsley Charitable Trust CGM Assessments of ENDIA Children (R-2205-05241) $358,741 Associate investigator International 2022 3 University of Western Australia
JDRF Australia Using 3D genomics to functionally connect genetic risk of T1D to immune genes (2-SRA-2022-1100-M-B) $565,085 Chief Investigator Domestic 2021 2 University of Adelaide
JDRF Australia Associations between IA risk and plasma proteins, cytokines and lipids (2-SRA-2022-1094-M-B) $212,063 Chief Investigator (first named) Domestic 2021 3 University of Adelaide
The Leona M. and Harry B. Helmsley Charitable Trust ENDIA Science Continuation (R-2112-04908) $2,141,466 Chief Investigator International 2021 3 University of Adelaide
The Leona M. and Harry B. Helmsley Charitable Trust ENDIA Expanded Support (R-2103-05117) $1,428,543 Chief Investigator (first named) International 2021 3 University of Adelaide
Diabetes SA Deep profiling for early biomarkers of progression to IA (FND000388) $100,000 Chief Investigator (first named) Domestic 2020 2 University of Adelaide
JDRF Australia and The Leona M. and Harry B. Helmsley Charitable Trust Partnership ENDIA 2020-2022 (3-SRA-2020-966-M-N) $8,253,170 Chief Investigator Domestic 2020 3 University of Adelaide
JDRF Australia, JDRF International, and The Leona M. and Harry B. Helmsley Charitable Trust ENDIA 2019 + supplement (1-SRA-2019-871-M-B) $4,064,074 Chief Investigator Domestic 2019 1 University of Adelaide
Women's and Children's Hospital Foundation Using CGM to characterise early dysglycaemia in children at risk of T1D (ORG102991) $75,000 Chief Investigator (first named) Domestic 2019 2 University of Adelaide
Australasian Paediatric Endocrine Group Using CGM to characterise early dysglycaemia in young children at risk of T1D $15,000 Associate investigator Domestic 2018 1 University of Western Australia
Diabetes Research Foundation of WA Inc Using CGM to characterise early dysglycaemia in young children (FND000927) $30,000 Associate investigator Domestic 2018 1 University of Western Australia
Diabetes SA The impact of modifiable exposures in the parents and childs environment on T1D risk (FND000388) $50,000 Chief Investigator Domestic 2018 2 University of Adelaide
JDRF International Testing the potential of human gut microbiota to prevent T1D in the NOD mouse (2-SRA-2019-731-S-B) $220,602 Chief Investigator International 2018 2 University of Queensland
JDRF International Maternal-infant microbiomes that precede the onset of islet autoimmunity (1-SRA-2018-543-S-B) $321,481 Chief Investigator International 2017 1 Walter and Eliza Hall Institute
University of Adelaide Robinson Research Institute Robinson Research Institute Engaging Opportunities Program $25,000 Associate investigator Domestic 2016 1 University of Adelaide
JDRF Australia, and The Leona M. and Harry B. Helmsley Charitable Trust Partnership ENDIA 2015-2018 (4-SRA-2015-127-M-B) $8,006,375 Project leader/manager Domestic 2015 4 University of Adelaide
University of Adelaide Robinson Research Institute Strike a Cord: the development and implementation of a RRI umbilical cord blood and placental tissue $10,000 Chief Investigator (first named) Domestic 2015 2 University of Adelaide
National Health and Medical Research Council (Centre of Research Excellence) Centre of Research Excellence for the Protection of Pancretic Beta Cells (APP1078106) $2,500,000 Project leader/manager Domestic 2014 5 University of Adelaide
University of Adelaide Robinson Research Institute Capacity Building in Bioinformatics and Biostatistics Funding Program $18,000 Chief Investigator (first named) Domestic 2013 1 University of Adelaide

Dr Penno’s teaching and supervisory contributions encompass Higher Degree by Research (HDR) supervision, research training, mentorship and leadership in research capacity building across the type 1 diabetes research community.

Dr Penno currently co-supervises two PhD candidates at the University of Adelaide and the University of Queensland, investigating the role of the exocrine pancreas and gut microbiota in type 1 diabetes progression. To strengthen researcher development across institutions, she established and convenes the ENDIA HDR Student Group, which supports training, collaboration and peer development among 12 HDR candidates from universities across Australia.

Beyond formal supervision, Dr Penno has played a significant role in mentoring PhD candidates, honours students, postdoctoral researchers and early-career investigators working within ENDIA and related national research programs. Through this mentorship, she has supported the development of research careers that have resulted in publications, fellowship success, national and international collaborations, and increasing research independence. She has also contributed to candidature and milestone reviews, honours thesis assessment, and postgraduate teaching through the University of Adelaide's Biology of Childhood Growth, Development and Health course.

Date Role Research Topic Program Degree Type Student Load Student Name
2025 Co-Supervisor The Exocrine Pancreas in the Progression to Type 1 Diabetes Doctor of Philosophy Doctorate Full Time Miss Madeleine Victoria Hall

Date Role Research Topic Location Program Supervision Type Student Load Student Name
2025 - ongoing Co-Supervisor Function of the gut microbiota during progression of T1D University of Adelaide University of Queensland Doctorate Full Time Mehran Radak

Date Topic Location Name
2025 - ongoing ENDIA HDR Student Group Convenor University of Adelaide ENDIA HDR Students
2015 - ongoing Specimen collection for pancreatic volume study Women's and Children's Hospital Priya Augustine
2013 - ongoing Microbiome studies involving the TIGS cohort University of Adelaide Jessica Harbison

Date Role Committee Institution Country
2026 - ongoing Member College of Health Low Risk Ethics Committee Adelaide University Australia
2025 - ongoing Member Faculty of Health and Medical Sciences Lower Risk Human Research Ethics Committee University of Adelaide Australia
2024 - 2026 Member Immunology of Diabetes Society 2026 Congress Scientific Program Committee Immunology of Diabetes Society United States
2024 - ongoing Member Breakthrough T1D T1DCRN Functional Genomics Interest Group Breakthrough T1D Australia Australia
2024 - 2025 Member JDRF Global Centre of Excellence Talent & Capacity Building Subcommittee Telethon Kids Institute Australia
2023 - 2026 Member Immunology of Diabetes Society 2026 Congress Local Organising Committee Immunology of Diabetes Society Australia
2021 - ongoing Member South Australian Biobanking Technical Reference Group The University of Adelaide Australia
2020 - 2020 Member New Women’s and Children’s Hospital Project User Groups: University Research Space, Library & Education Training Spaces, Research Secretariat Women's and Children's Hospital Australia
2019 - ongoing Member Research Freezer Management Policy Working Group The University of Adelaide Australia
2018 - 2019 Member DOHaD World Congress Symposium Sub-Committee DOHaD Society Australia
2016 - ongoing Member Health Consumer Engagement Executive Subcommittee University of Adelaide, Robinson Research Institute Australia
2016 - 2016 Member RRI 2016 Symposium Organising Committee University of Adelaide, Robinson Research Institute Australia
2016 - ongoing Founder RRI Early/Mid Career Researcher Committee University of Adelaide, Robinson Research Institute Australia
2016 - ongoing Chair ENDIA Steering Committee ENDIA Study Group Australia
2016 - ongoing Member ENDIA Steering Committee Executive The ENDIA Study Australia
2015 - ongoing Member The High Performance Researcher Group ThinkWell Australia
2014 - 2015 Member Adelaide Family Health Study Protocol Development Working Group The University of Adelaide, Robinson Research Institute Australia
2014 - ongoing Founder Robinson Research Institute Study Coordinator Network Advisory Committee The University of Adelaide, Robinson Research Institute Australia
2013 - ongoing Member Robinson Research Institute CIS Facility Steering Group University of Adelaide, Robinson Research Institute Australia
2013 - ongoing Member JDRF International Microbiome Consortium JDRF International Australia
2007 - 2009 Member Adelaide Protein Group Australian Society for Biochemistry and Molecular Biology Australia

Date Title Type Institution Country
2026 - 2026 Breakthrough T1D FY26 SRA Project Concept Review Panel Grant Assessment Breakthrough T1D United States
2025 - 2025 Breakthrough T1D Fellowships Review Panel Grant Assessment Breakthrough T1D Australia
2025 - 2025 Breakthrough T1D International Training Award Review Panel Grant Assessment Breakthrough T1D International United States

Connect With Me

External Profiles