Megan Penno

Research Interests

Autoimmunity Clinical Microbiology Clinical Trials Endocrinology & Metabolism Medical Biochemistry: Proteins and Peptides Child and Adolescent Health Early Origins of Health Pregnancy and Birth

Dr Megan Penno

Grant-Funded Researcher (C)

School of Medicine

College of Health

Dr Megan Penno (BSc Hons PhD, University of Melbourne) is the Chief Operating Officer for the Environmental Determinants of Islet Autoimmunity (ENDIA) study and Grant-Funded Research at the University of Adelaide, Australia. ENDIA is the first study in the world to explore how environmental exposures from pregnancy through early life may contribute to, or protect against, the development of childhood type 1 diabetes. Dr Penno was appointed to manage ENDIA at the project’s inception in 2012 and has played an integral role in establishing and expanding the cohort, which completed recruitment of 1500 mother-infant dyads in late 2019. Drawing on her skills in ‘omics research, Dr Penno was the first author of the published ENDIA protocol and developed the sample and data collection strategies that will underpin all future investigations involving ENDIA participants. She has contributed to numerous successful national and international funding applications relating to ENDIA with a total value exceeding AU$30m over the past 5 years. Her research interests include biomarker discovery for disease risk stratification. 

For more information about the ENDIA study please visit our website at http://www.endia.org.au

ENDIA team

Date Position Institution name
2019 - ongoing Grant Funded Researcher University of Adelaide
2015 - 2018 Academic Research Clinical Coordinator University of Adelaide
2012 - 2014 Senior Clinical Research Coordinator University of Adelaide
2007 - 2012 Post-doctoral fellow University of Adelaide
2006 - 2006 Grant Funded Scientist Hanson Institute

Date Type Title Institution Name Country Amount
2022 Research Award Faculty of Health and Medical Sciences Executive Dean's Award for Research Excellence (mid-career) The University of Adelaide Australia -
2020 Award IDS 17th Congress High-Scoring Abstracts Award Immunology of Diabetes Society China -
2018 Award CUDOS 2018 Conference poster prize Sidra Medicine Qatar -
2018 Nomination JDRF Australia & Macquarie Group Foundation Future Leader Program JDRF Australia Australia -
2014 Award Robinson Research Institute Travel Award University of Adelaide, Robinson Research Institute Australia $1,100
2011 Award Research Career Development Network (RCDN) Workshop Award University of Adelaide, School of Molecular and Biomedical Sciences Australia $2,000
2008 Award Overseas Conference Scheme Travel Award University of Adelaide, Faculty of Science Australia $2,000
2004 Award American Society for Biochemistry and Molecular Biology Graduate Travel Award The American Society for Biochemistry and Molecular Biology United States US$1,000
2004 Award Dawson Bursary The University of Melbourne Australia $6,000
2004 Award School of Botany Travel Scholarship The University of Melbourne, School of Botany Australia -
2003 Scholarship Sir John and Lady Higgins Research Scholarship The University of Melbourne Australia $70,000

Language Competency
English Can read, write, speak, understand spoken and peer review

Date Institution name Country Title
2003 - 2007 University of Melbourne Australia PhD
1999 - 2002 University of Melbourne Australia BSc (Honours)

Year Citation
2026 Thomson, R. L., Martin, G., Brown, J. D., Oakey, H., Ashwood, P., Penno, M. A. S., . . . ENDIA Study Group*. (2026). A Comparison of Diet and Exercise During Pregnancy in Women With and Without Type 1 Diabetes Followed in the Environmental Determinants of Islet Autoimmunity(ENDIA) Study. Diabetes Care, 49(3), dc252064-1-dc252064-7.
DOI
2025 Walker, G. J., Mallitt, K. -A., Craig, M. E., Ashwood, P., Barry, S. C., Brown, J. D., . . . ENDIA Study Group. (2025). SARS-CoV-2 Infection and Childhood Islet Autoimmunity. JAMA Pediatrics, 179(5), 568-570.
DOI Scopus3 WoS3 Europe PMC2
2025 Roth-Schulze, A. J., Bandala-Sanchez, E., Ngui, K. M., Naselli, G., Oakey, H., Ashwood, P., . . . ENDIA Study Group. (2025). Adverse pregnancy outcomes in women with type 1 diabetes are associated with multiple alterations in the vaginal microbiome. Diabetologia, 68(11), 2552-2566.
DOI
2025 Haynes, A., Smith, G. J., Tully, A., Mellor, B. R., Penno, M. A. S., Craig, M. E., . . . Davis, E. A. (2025). Longitudinal Continuous Glucose Monitoring Study in Young Children With Presymptomatic Type 1 Diabetes Followed in the Environmental Determinants of Islet Autoimmunity (ENDIA) At-Risk Cohort Study. Diabetes Care, 48(10), 1812-1817.
DOI
2025 Thomson, R. L., Martin, G., McGorm, K. J., Spelman, T., Craig, M. E., Penno, M. A. S., . . . ENDIA Study Group. (2025). Perceived stress in mothers of children with and without islet and coeliac autoimmunity in the ENDIA study. Diabetologia, 69(2), 1-7.
DOI
2025 Harrison, L. C., Allnutt, T. R., Hanieh, S., Roth-Schulze, A. J., Ngui, K. M., Stone, N. L., . . . Ashwood, P. (2025). Indigenous infants in remote Australia retain an ancestral gut microbiome despite encroaching Westernization. Nature Communications, 16(1), 15 pages.
DOI
2025 Couper, J. J., Oakey, H., Penno, M. A. S., Wentworth, J. M., Watson, K., Brown, J. D., . . . ENDIA Study Group. (2025). Evolution of islet autoantibodies in the Environmental Determinants of Islet Autoimmunity (ENDIA) prospective cohort. Diabetologia, 1-12.
DOI Scopus1
2024 Thomson, R. L., Oakey, H., Haynes, A., Craig, M. E., Harrison, L. C., Wentworth, J. M., . . . Couper, J. J. (2024). Environmental Determinants of Islet Autoimmunity (ENDIA) longitudinal prospective pregnancy to childhood cohort study of Australian children at risk of type 1 diabetes: parental demographics and birth information. BMJ Open Diabetes Research & Care, 12(4), e004130-1-e004130-13.
DOI Scopus6 WoS6 Europe PMC6
2024 Haynes, A., Tully, A., Smith, G. J., Penno, M. A. S., Craig, M. E., Wentworth, J. M., . . . ENDIA Study Group. (2024). Early Dysglycemia Is Detectable Using Continuous Glucose Monitoring in Very Young Children at Risk of Type 1 Diabetes.. Diabetes care, 47(10), 1750-1756.
DOI Scopus10 WoS8 Europe PMC8
2024 Thomson, R. L., Brown, J. D., Oakey, H., Palmer, K., Ashwood, P., Penno, M. A. S., . . . ENDIA Study Group. (2024). Dietary patterns during pregnancy and maternal and birth outcomes in women with type 1 diabetes: the Environmental Determinants of Islet Autoimmunity (ENDIA) study. Diabetologia, 67(11), 2420-2432.
DOI Scopus2 WoS2 Europe PMC2
2024 Roberts, A. G., Tully, A. S., Binkowski, S. K., Bebbington, K. R., Penno, M. A. S., Anderson, A. J., . . . Haynes, A. (2024). Parental experiences of using continuous glucose monitoring in their young children with early-stage type 1 diabetes: a qualitative interview study. Frontiers in Clinical Diabetes and Healthcare, 5, 7 pages.
DOI
2023 Harrison, L. C., Bandala-Sanchez, E., Oakey, H., Colman, P. G., Watson, K., Kim, K. W., . . . ENDIA Study Group. (2023). A surge in serum mucosal cytokines associated with seroconversion in children at risk for type 1 diabetes. Journal of Diabetes Investigation, 14(9), 1092-1100.
DOI
2023 Oakey, H., Giles, L. C., Thomson, R. L., Le Cao, K. -A., Ashwood, P., Brown, J. D., . . . ENDIA, S. G. (2023). Protocol for a nested case- control study design for omics investigations in the environmental determinants of islet autoimmunity cohort (vol 55, 2198255, 2023). ANNALS OF MEDICINE, 55(1), 1 page.
DOI
2023 McGorm, K. J., Brown, J. D., Roberts, A. G., Greenbank, S., Brasacchio, D., Sawyer, A. C. P., . . . Penno, M. A. S. (2023). Experiences of Caregivers and At-Risk Children Enrolled in a Prospective Pregnancy-Birth Cohort Study into the Causes of Type 1 Diabetes: The ENDIA Study. Children, 10(4), 637.
DOI Scopus2 WoS2 Europe PMC2
2023 Oakey, H., Giles, L. C., Thomson, R. L., Lê Cao, K. -A., Ashwood, P., Brown, J. D., . . . ENDIA Study Group. (2023). Protocol for a nested case-control study design for omics investigations in the Environmental Determinants of Islet Autoimmunity cohort. Annals of Medicine, 55(1), 1-14.
DOI Scopus7 WoS8 Europe PMC7
2023 McGorm, K. J., Brown, J. D., Thomson, R. L., Oakey, H., Moore, B., Hendry, A., . . . Penno, M. A. S. (2023). A Long-Term Evaluation of Facebook for Recruitment and Retention in the ENDIA Type 1 Diabetes Pregnancy-Birth Cohort Study. Journal of Diabetes Science and Technology, 17(3), 696-704.
DOI Scopus4 WoS3 Europe PMC4
2022 Bandala-Sanchez, E., Roth-Schulze, A. J., Oakey, H., Penno, M. A. S., Bediaga, N. G., Naselli, G., . . . ENDIA Study Group. (2022). Women with type 1 diabetes exhibit a progressive increase in gut Saccharomyces cerevisiae in pregnancy associated with evidence of gut inflammation.. Diabetes research and clinical practice, 184, 1-23.
DOI Scopus11 WoS11 Europe PMC11
2022 Hall, M., Oakey, H., Penno, M. A. S., McGorm, K., Anderson, A. J., Ashwood, P., . . . Cavenett, L. (2022). Mental Health During Late Pregnancy and Postpartum in Mothers With and Without Type 1 Diabetes: The ENDIA Study. Diabetes Care, 45(5), 1082-1090.
DOI Scopus4 WoS3 Europe PMC5
2021 Penno, M. A., Anderson, A. J., Thomson, R. L., McGorm, K., Barry, S. C., Colman, P. G., . . . ENDIA Study Group. (2021). Evaluation of protocol amendments to the Environmental Determinants of Islet Autoimmunity (ENDIA) study during the COVID-19 pandemic. Diabetic Medicine, 38(11), e14638-1-e14638-4.
DOI Scopus3 WoS2 Europe PMC3
2021 Roth-Schulze, A. J., Penno, M. A. S., Ngui, K. M., Oakey, H., Bandala-Sanchez, E., Smith, A. D., . . . Harrison, L. C. (2021). Type 1 diabetes in pregnancy is associated with distinct changes in the composition and function of the gut microbiome. Microbiome, 9(1), 167-1-167-21.
DOI Scopus32 WoS30 Europe PMC28
2021 Harbison, J. E., Thomson, R. L., Wentworth, J. M., Louise, J., Roth‐Schulze, A., Battersby, R. J., . . . Couper, J. J. (2021). Associations between diet, the gut microbiome and short chain fatty acids in youth with islet autoimmunity and type 1 diabetes. Pediatric Diabetes, 22(3), 425-433.
DOI Scopus9 WoS8 Europe PMC8
2021 Hope, C. M., Huynh, D., Wong, Y. Y., Oakey, H., Perkins, G. B., Nguyen, T., . . . Barry, S. C. (2021). Optimization of blood handling and peripheral blood mononuclear cell cryopreservation of low cell number samples. International Journal of Molecular Sciences, 22(17), 9129-1-9129-19.
DOI Scopus22 WoS20 Europe PMC19
2020 Augustine, P., Gent, R., Louise, J., Taranto, M., Penno, M., Linke, R., . . . ENDIA Study Group. (2020). Pancreas size and exocrine function is decreased in young children with recent-onset Type 1 diabetes. Diabetic Medicine, 37(8), 1340-1343.
DOI Scopus22 WoS20 Europe PMC19
2020 Begum, M., Pilkington, R. M., Chittleborough, C. R., Lynch, J. W., Penno, M., & Smithers, L. G. (2020). Effect of maternal smoking during pregnancy on childhood type 1 diabetes: a whole-of-population study. Diabetologia, 63(6), 1162-1173.
DOI Scopus8 WoS8 Europe PMC5
2020 Penno, M. A., Oakey, H., Augustine, P., Taranto, M., Barry, S. C., Colman, P. G., . . . Couper, J. J. (2020). Changes in pancreatic exocrine function in young at-risk children followed to islet autoimmunity and type 1 diabetes in the ENDIA study. Pediatric Diabetes, 21(6), 945-949.
DOI Scopus11 WoS10 Europe PMC10
2020 Begum, M., Chittleborough, C., Pilkington, R., Mittinty, M., Lynch, J., Penno, M., & Smithers, L. (2020). Educational outcomes among children with type 1 diabetes: whole-of-population linked-data study. Pediatric Diabetes, 21(7), 1353-1361.
DOI Scopus13 WoS12 Europe PMC12
2020 Begum, M., Chittleborough, C., Pilkington, R., Mittinty, M., Lynch, J., Penno, M., & Smithers, L. (2020). Incidence of type 1 diabetes by socio-demographic characteristics among South Australian children: Whole-of-population study. Journal of Paediatrics and Child Health, 56(12), 1985-1958.
DOI Scopus4 WoS5 Europe PMC5
2019 Kim, K. W., Allen, D. W., Briese, T., Couper, J. J., Barry, S. C., Colman, P. G., . . . ENDIA STUDY GROUP. (2019). Higher frequency of vertebrate-infecting viruses in the gut of infants born to mothers with type 1 diabetes. Pediatric Diabetes, 21(2), 271-279.
DOI Scopus12 WoS10 Europe PMC12
2019 Kedzior, S., Bianco-Miotto, T., Breen, J., Diener, K. R., Donnelley, M. W., Dunning, K. R., . . . Rumbold, A. R. (2019). It takes a community to conceive: an analysis of the scope, nature and accuracy of online sources of health information for couples trying to conceive. Reproductive Biomedicine and Society Online, 9, 48-63.
DOI Scopus11 Europe PMC12
2019 Craig, M. E., Kim, K. W., Isaacs, S. R., Penno, M. A., Hamilton-Williams, E. E., Couper, J. J., & Rawlinson, W. D. (2019). Early-life factors contributing to type 1 diabetes. Diabetologia, 62(10), 1823-1834.
DOI Scopus91 WoS81 Europe PMC72
2019 Begum, M., Pilkington, R., Chittleborough, C., Lynch, J., Penno, M., & Smithers, L. (2019). Caesarean section and risk of type 1 diabetes: whole-of-population study. Diabetic medicine : a journal of the British Diabetic Association, 36(12), 1686-1693.
DOI Scopus17 WoS17 Europe PMC15
2019 Ziegler, A., Hoffmann, G. F., Hasford, J., Elding Larsson, H., Danne, T., Berner, R., . . . Bonifacio, E. (2019). Screening for asymptomatic β-cell autoimmunity in young children. Lancet Child and Adolescent Health, 3(5), 288-290.
DOI Scopus11 WoS11 Europe PMC9
2019 Wook Kim, K., Allen, D. W., Briese, T., Couper, J. J., Barry, S. C., Colman, P. G., . . . ENDIA Study Group. (2019). Distinct gut virome profile of pregnant women with type 1 diabetes in the ENDIA study. Open forum infectious diseases, 6(2), 1-8.
DOI Scopus42 WoS39 Europe PMC31
2019 Harbison, J. E., Roth-Schulze, A. J., Giles, L. C., Tran, C. D., Ngui, K. M., Penno, M. A., . . . Couper, J. J. (2019). Gut microbiome dysbiosis and increased intestinal permeability in children with islet autoimmunity and type 1 diabetes: a prospective cohort study. Pediatric Diabetes, 20(5), 574-583.
DOI Scopus124 WoS108 Europe PMC103
2018 Penington, J., Penno, M., Ngui, K., Ajami, N., Roth-Schulze, A., Wilcox, S., . . . Vuillermin, P. (2018). Influence of fecal collection conditions and 16S rRNA gene sequencing at two centers on human gut microbiota analysis. Scientific Reports, 8(1), 4386-1-4386-10.
DOI Scopus45 WoS44 Europe PMC41
2018 Wentworth, J. M., Bediaga, N. G., Penno, M. A., Bandala-Sanchez, E., Kanojia, K. N., Kouremenos, K. A., . . . ENDIA, S. G. (2018). Minimal variation of the plasma lipidome after delayed processing of neonatal cord blood. Metabolomics, 14(10), 130-1-130-3.
DOI Scopus1 WoS1 Europe PMC1
2018 Penington, J. S., Penno, M., Ngui, K., Ajami, N., Roth-Schulze, A., Wilcox, S., . . . Giles, L. (2018). Influence of fecal collection conditions and 16S rRNA gene sequencing protocols at two centers on human gut microbiota analysis. Scientific Reports, 8, 10 pages.
DOI
2017 Phillips, J., Couper, J., Penno, M., & Harrison, L. (2017). Type 1 diabetes: a disease of developmental origins. Pediatric Diabetes, 18(6), 417-421.
DOI Scopus11 WoS11 Europe PMC9
2016 Penno, M. A. S., Thomson, R. L., & Couper, J. J. (2016). Bunbury to Bundaberg, Darwin to Dover: establishing a successful Regional Participation Program for the ENDIA type 1 diabetes cohort study. The Medical journal of Australia, 205(10), 486-486.e1.
DOI Scopus6 WoS6 Europe PMC6
2014 Humphries, J., Penno, M., Weiland, F., Klingler-Hoffmann, M., Zuber, A., Boussioutas, A., . . . Hoffmann, P. (2014). Identification and validation of novel candidate protein biomarkers for the detection of human gastric cancer. Biochimica et Biophysica Acta - Proteins and Proteomics, 1844(5), 1051-1058.
DOI Scopus54 WoS52 Europe PMC40
2013 Penno, M., Couper, J., Craig, M., Colman, P., Rawlinson, W., Cotterill, A., . . . Wentworth, J. (2013). Environmental determinants of islet autoimmunity (ENDIA): a pregnancy to early life cohort study in children at-risk of type 1 diabetes. BMC Pediatrics, 13(1), 1-15.
DOI Scopus74 WoS66 Europe PMC61
2013 Sciacca, B., François, A., Klingler-Hoffmann, M., Brazzatti, J., Penno, M., Hoffmann, P., & Monro, T. (2013). Radiative-surface plasmon resonance for the detection of apolipoprotein E in medical diagnostics applications. Nanomedicine: Nanotechnology, Biology & Medicine, 9(4), 550-557.
DOI Scopus52 WoS38 Europe PMC14
2012 Penno, M., Klingler-Hoffmann, M., Brazzatti, J., Boussioutas, A., Putoczki, T., Ernst, M., & Hoffmann, P. (2012). 2D-DIGE analysis of sera from transgenic mouse models reveals novel candidate protein biomarkers for human gastric cancer. Journal of Proteomics, 77, 40-58.
DOI Scopus26 WoS25 Europe PMC21
2012 Penno, M., Colegate, S., Michalski, W., & Hoffmann, P. (2012). Detection and measurement of carbohydrate deficient transferrin in serum using immuno-capture mass spectrometry: Diagnostic applications for annual ryegrass toxicity and corynetoxin exposure. Research in Veterinary Science, 93(2), 611-617.
DOI Scopus4 WoS3 Europe PMC2
2012 Ho, Y., Penno, M., Perugini, M., Lewis, I., & Hoffmann, P. (2012). Evaluating the efficacy of subcellular fractionation of blast cells using live cell labeling and 2D DIGE. Methods in molecular biology, 854, 319-332.
DOI
2012 Penno, M., Ernst, M., & Hoffmann, P. (2012). Comparative 2D DIGE analysis of the depleted serum proteome for biomarker discovery. Methods in molecular biology, 854, 207-220.
DOI Scopus3 Europe PMC4
2012 Kopetz, V., Penno, M., Hoffmann, P., Wilson, D., & Beltrame, J. (2012). Potential mechanisms of the acute coronary syndrome presentation in patients with the coronary slow flow phenomenon - Insight from a plasma proteomic approach. International Journal of Cardiology, 156(1), 84-91.
DOI Scopus39 WoS33 Europe PMC28
2009 Penno, M., Ernst, M., & Hoffmann, P. (2009). Optimal preparation methods for automated matrix-assisted laser desorption/ionization time-of-flight mass spectrometry profiling of low molecular weight proteins and peptides. Rapid Communications in Mass Spectrometry, 23(17), 2656-2662.
DOI Scopus23 WoS23 Europe PMC23
2009 Penno, M., Bacic, A., Colegate, S., Hoffmann, P., & Michalski, W. (2009). Identifying candidate serum biomarkers of exposure to tunicamycins in rats using two-dimensional electrophoresis. Journal of Proteome Research, 8(6), 2812-2826.
DOI Scopus4 WoS4 Europe PMC4
2006 Aslani, M., Pascoe, I., Kowalski, M., Michalewicz, A., Penno, M., & Colegate, S. (2006). In vitro detection of hepatocytotoxic metabolites from Drechslera biseptata: a contributing factor to acute bovine liver disease?. Australian Journal of Experimental Agriculture, 46(5), 599-604.
DOI WoS7

Year Citation
2007 Allen, J. G., Retallick, M., Kowalski, M., Colegate, S. M., Speijers, E. J., Doran, T., . . . others. (2007). A study of the bioequivalence of corynetoxins and tunicamycins: the effect of these toxins on the viability and morphology of rat hepatocytes in tissue culture.. In Unknown Book (pp. 504-510). CABI.
2007 Retallick, M. A. S., Colegate, S. M., Michalski, W. P., Panter, K. E., Wierenga, T. L., Pfister, J. A., & others. (2007). A toxicoproteomic approach to understanding annual ryegrass toxicity.. In Unknown Book (pp. 230-234). CABI.

Year Citation
2024 Walker, G., Mallitt, K. -A., Sevendal, A., Ward, E., Caguicla, J., Naing, Z., . . . Rawlinson, W. (2024). No increased risk of islet autoimmunity following SARS-CoV-2 infection in ENDIA children. In HORMONE RESEARCH IN PAEDIATRICS Vol. 97 (pp. 198). KARGER.
2023 Thomson, R. L., Brown, J. D., Oakey, H., Penno, M. A. S., Battersby, R., Ashwood, P., . . . Couper, J. J. (2023). A comparison of lifestyle during pregnancy against Australian recommendations of women with and without type 1 diabetes from the Environmental Determinants of Islet Autoimmunity study. In PROCEEDINGS OF THE NUTRITION SOCIETY Vol. 82 (pp. 1 page). CAMBRIDGE UNIV PRESS.
DOI
2022 Haynes, A., Tully, A., Smith, G. J., Penno, M. A. S., Craig, M. E., Wentworth, J. M., . . . Davis, E. A. (2022). Continuous glucose monitoring identifies early dysglycaemia in very young children at risk of type 1 diabetes being followed in the Australian ENDIA pregnancy cohort study. In DIABETOLOGIA Vol. 65 (pp. S173-S174). SWEDEN, Stockholm: SPRINGER.
2019 Haynes, A., Giles, L., Penno, M., Thomson, R., McGorm, K., Colman, P., . . . ENDIA Study Group. (2019). Cohort profile: the Australia-wide environmental determinants of islet autoimmunity (ENDIA) study. In Diabetologia Vol. 62 (pp. S139-S140). Barcelona, Spain: Springer.
2019 Begum, M., Pilkington, R. M., Chittleborough, C. R., Lynch, J. W., Penno, M., & Smithers, L. G. (2019). MATERNAL SMOKING DURING PREGNANCY AND RISK OF TYPE 1 DIABETES: WHOLE-OF-POPULATION STUDY. In JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH Vol. 73 (pp. A36-A37). BMJ PUBLISHING GROUP.
DOI
2019 Begum, M., Chittleborough, C. R., Pilkington, R. M., Mittinty, M., Lynch, J. W., Penno, M., & Smithers, L. G. (2019). EDUCATIONAL OUTCOMES AMONG CHILDREN WITH TYPE 1 DIABETES: WHOLE-OF-POPULATION STUDY. In JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH Vol. 73 (pp. A55-A56). BMJ PUBLISHING GROUP.
DOI
2018 Harbison, J. E., Roth-Schulze, A. J., Barry, S. C., Tran, C. D., Ngui, K., Penno, M. A., . . . Couper, J. (2018). Gut Microbiome Dysbiosis and Increased Intestinal Permeability in Australian Children with Islet Autoimmunity and Type 1 Diabetes. In DIABETES Vol. 67 (pp. 2 pages). Orlando, FL: AMER DIABETES ASSOC.
DOI WoS2
2017 Kim, K. W., Allen, D. W., Briese, T., Pang, C. N., Jain, K., Horton, J. L., . . . Craig, M. E. (2017). Gut Virome Dynamics during Pregnancy in Mothers with Type 1 Diabetes. In Abstracts of the 77th Scientific Sessions of the American Diabetes Association, as published in Diabetes Vol. 66 (pp. LB192). San Diego, CA: American Diabetes Association.
2017 Thomson, R., Penno, M. A., Battersby, R., & Couper, J. (2017). Are pregnant women meeting the Australian dietary guidelines? A comparison of women with and without Type 1 diabetes. In Journal of Nutrition and Intermediary Metabolism Vol. 8 (pp. 76-77). Melbourne: Elsevier.
DOI
2012 Sciacca, B., François, A., Penno, M., Brazzatti, J., Klingler-Hoffmann, M., Hoffmann, P., & Monro, T. (2012). Radiative-SPR platform for the detection of apolipoprotein E for use in medical diagnostics. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE Vol. 8234 (pp. 1-8). US: SPIE.
DOI Scopus1
2011 François, A., Courtney, J., Penno, M., Hoffmann, P., & Monro, T. (2011). A novel optical-fiber based surface plasmon resonance sensing architecture and its application to gastric cancer diagnostics. In W. Bock, J. Albert, & X. Bao (Eds.), Proceedings of SPIE Vol. 7753 (pp. 1-4). Ottawa, Canada: SPIE.
DOI Scopus3 WoS1
2008 Kopetz, V., Penno, M., Hoffmann, P., & Beltrame, J. (2008). Plasma Proteomic Investigations in the Coronary Slow Flow Phenomenon: Exploring Mechanisms for the Acute Coronary Syndrome Presentation. In Heart, Lung and Circulation Vol. 17 (pp. S235). Elsevier BV.
DOI

Year Citation
2015 Hoffmann, P., Penno, M., & Ernst, M. R. W. (2015). BIOMARKERS FOR GASTRIC CANCER AND USES THEREOF.

I have significantly contributed to numerous successful funding applications totalling >AU$31 million in the past 5 years:

  • 2023 Croatian Science Foundation (Hrvatske zaklade za znanost), Research projects (Istraživački projekti) ‘Glycosylation of complement component C3 in development of type 1 diabetes and autoimmunity’ (Gornik O, Keser T, Rudman N, Kifer D, Pape-Medvidovic E, Vucic Lovrencic M, Penno M, Morahan G). AU$309,284.51
  • 2023 NHMRC EU Collaborative Research Grant ‘Characterising viruses that promote the development of type 1 diabetes’ (Kim KW, Craig M, Foster C, Walker G, Harrison L, Rawlinson W, Couper J, Penno M, Mallitt K, Oakey H). AU$499,999.45
  • 2023 JDRFA T1DCRN and Helmsley Charitable Trust Partnership Establishing immune, endocrine, and exocrine signatures of type 1 diabetes progression in longitudinally sampled peripheral blood from the ENDIA nested case control study (Wasserfall C, Couper J, Penno M). AU$226,897.31
  • 2023 JDRFA T1DCRN and Helmsley Charitable Trust Partnership Deep milk: comprehensive multi-omics to resolve the role of human breastmilk in type 1 diabetes risk (Burugupalli S, Hamilton-Williams E, Harrison L, Oakey H, Penno M, Thomson R, Wentworth J, Huynh D, Meikle P, Packer N, Paul S, George A). AU$795,973.96
  • 2023 JDRFA T1DCRN and Helmsley Charitable Trust Partnership ‘The effect of metabolism in pregnancy upon islet autoimmunity and pancreatic beta cell function in offspring’ (Meek C, Couper J, Penno M, Hamilton-Williams E, Wentworth J). AU$792,694.17
  • 2023 JDRFA T1DCRN and Helmsley Charitable Trust Partnership ‘Familial Sharing of Gut Microbes and Mobile Genetic Elements in the ENDIA Study’ (Vatanen T, Harrison L, Penno M). AU$401,065.74
  • 2023 JDRFA T1DCRN and Helmsley Charitable Trust Partnership Epigenomic ‘Mechanisms of the Maternal Protection in Type 1 Diabetes’ (Johnson R, Penno M, Norris J, Kechris K, Barry S, Couper J, Wong Y). AU$799,998.64
  • 2023 Leona M. and Harry B. Helmsley Charitable Trust - Research Grant ‘Pancreatic exocrine function and the progression to type 1 diabetes in young children in ENDIA’ (Couper J, Penno M, Linke R, Gent R, Rankin W, Oakey H, Wentworth J, Haynes A). AU$316,027
  • 2023 JDRF Australia 'Australian Type 1 Diabetes Clinical Research Network & The Helmsley Charitable Trust – ENDIA Follow Up 2023 - 2025' (Couper J, Penno M, Craig M, Wentworth J, Colman P, Harrison L, Davis E, Haynes A, Harris M, Soldatos G, Oakey H, Sinnott R, Thomson R, McGorm K, Vuillermin P). AU$8,977,646
  • 2022 NHMRC 'A microRNA NanoChip Technology for Predicting Childhood Type 1 Diabetes Risk' (Hardikar A, Couper J, Dubey A, Penno M, Joglekar M). AU$390,167
  • 2021 JDRF Australia 'Using 3D genomics to functionally connect genetic risk of Type 1 diabetes to the genes that drive loss of immune tolerance' (Barry S, Wong Y, Penno M, Sadlon T, Couper J, Breen J, Oakey H). AU$505,085
  • 2021 The Leona M. and Harry B. Helmsley Charitable Trust 'CGM Assessments of ENDIA Children' (Haynes A, Davis E, Couper J, Penno M). US$230,319
  • 2021 The Leona M. and Harry B. Helmsley Charitable Trust 'ENDIA Expanded Support' (Penno M, Couper J, Oakey H, Thomson R, Ashwood P, Brown J, Sinnott R, Harrison L, Colman P, Wentworth J, Soldatos G, Vuillermin P, Craig M, Rawlinson W, Harris M, Davis E, Haynes A). US$1,428,543
  • 2021 The Leona M. and Harry B. Helmsley Charitable Trust 'ENDIA Science Continuation' (Couper J, Penno M, Harrison L, Craig M, Oakey H, Kim K, Rawlinson W, Morahan G). US$2,067,727
  • 2020 Diabetes SA Research Grant "Deep profiling for early biomarkers of progression to islet autoimmunity and type 1 diabetes in mother-infant dyads participating in the ENDIA study" (CIA Penno, CIB Couper, CIC Harrison, CID Wentworth, CIE Knight). AU$100,000
  • 2020 JDRF, T1DCRN and The Leona M. and Harry B. Helmsley Charitable Trust Request for Application "Australian Type 1 Diabetes Clinical research Network – ENDIA 2020/2022" (3-SRA-2020-966-M-N: CIA Couper, CIB Harrison, CIC Craig, CID Penno, et al). AU$8,253,170
  • 2019 JDRF, T1DCRN and The Leona M. and Harry B. Helmsley Charitable Trust Request for Application "ENDIA 2019" (CIA Couper, CIB Harrison, CIC Craig, CID Penno, et al). AU$4,064,074

 

My teaching and supervisory contributions span formal Higher Degree by Research (HDR) supervision, informal mentorship, and broader leadership in research training. 

I currently co-supervise two PhD candidates working on the exocrine pancreas and gut microbiota in T1D progression at Adelaide University and University of Queensland, respectively. I also convene the ENDIA HDR Student Group to support cohort-wide training and peer development, which involved 12 HDR student from various Universities across Australia. 

I have played a substantial role in shaping the careers of multiple PhD candidates, honours students, and postdoctoral researchers working on ENDIA and related T1D projects, contributing to publications, fellowships, and international recognition. I have also served on candidature and review panels, assessed honours theses, lectured in the Biology of Childhood Growth, Development & Health course at the University of Adelaide, and mentored early-career researchers across several national cohorts. 

This sustained involvement reflects my commitment to developing research capacity and supporting the next generation of investigators in T1D.

Date Role Research Topic Program Degree Type Student Load Student Name
2025 Co-Supervisor The Exocrine Pancreas in the Progression to Type 1 Diabetes Doctor of Philosophy Doctorate Full Time Miss Madeleine Victoria Hall
2025 Co-Supervisor The Exocrine Pancreas in the Progression to Type 1 Diabetes Doctor of Philosophy Doctorate Full Time Miss Madeleine Victoria Hall

Date Role Research Topic Location Program Supervision Type Student Load Student Name
2025 - ongoing Co-Supervisor Function of the gut microbiota during progression of T1D University of Adelaide University of Queensland Doctorate Full Time Mehran Radak

Date Topic Location Name
2025 - ongoing ENDIA HDR Student Group Convenor University of Adelaide ENDIA HDR Students
2015 - ongoing Specimen collection for pancreatic volume study Women's and Children's Hospital Priya Augustine
2013 - ongoing Microbiome studies involving the TIGS cohort University of Adelaide Jessica Harbison

Date Role Committee Institution Country
2025 - ongoing Member Faculty of Health and Medical Sciences Lower Risk Human Research Ethics Committee University of Adelaide Australia
2021 - ongoing Member South Australian Biobanking Technical Reference Group The University of Adelaide Australia
2019 - ongoing Member Research Freezer Management Policy Working Group The University of Adelaide Australia
2016 - ongoing Member Health Consumer Engagement Executive Subcommittee University of Adelaide, Robinson Research Institute Australia
2016 - 2016 Member RRI 2016 Symposium Organising Committee University of Adelaide, Robinson Research Institute Australia
2016 - ongoing Founder RRI Early/Mid Career Researcher Committee University of Adelaide, Robinson Research Institute Australia
2016 - ongoing Chair ENDIA Steering Committee ENDIA Study Group Australia
2016 - ongoing Member ENDIA Steering Committee Executive The ENDIA Study Australia
2015 - ongoing Member The High Performance Researcher Group ThinkWell Australia
2014 - 2015 Member Adelaide Family Health Study Protocol Development Working Group The University of Adelaide, Robinson Research Institute Australia
2014 - ongoing Founder Robinson Research Institute Study Coordinator Network Advisory Committee The University of Adelaide, Robinson Research Institute Australia
2013 - ongoing Member Robinson Research Institute CIS Facility Steering Group University of Adelaide, Robinson Research Institute Australia
2013 - ongoing Member JDRF International Microbiome Consortium JDRF International Australia
2007 - 2009 Member Adelaide Protein Group Australian Society for Biochemistry and Molecular Biology Australia

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