Mark Van Der Hoek

Mr Mark Van Der Hoek

Research Coordinator

SAIGENCI

College of Health

Mark Van der Hoek is a research coordinator working under Dr. Joanna Achinger-Kawecka in the 3D Chromatin Organisation Laboratory within SAiGENCI.  Mark has a long career in genomics service provision having helped establish the Adelaide Microarray Centre in the early 2000’s, the ACRF Cancer Genomics Facility at SA Pathology, the SAHMRI Genomics core facility and the SAGC.  A long-term executive member of AGTA, he has extensive experience in establishing cutting-edge platforms and protocols including for single cell analysis and next generation sequencing.  He is currently helping to establish epigenetics protocols in the laboratory for the study of cancer treatment resistance.

Year Citation
2023 Archer, M., Bernhardt, S. M., Hodson, L. J., Woolford, L., Van der Hoek, M., Dasari, P., . . . Ingman, W. V. (2023). CCL2-Mediated Stromal Interactions Drive Macrophage Polarization to Increase Breast Tumorigenesis. International Journal of Molecular Sciences, 24(8), 7385-1-7385-26.
DOI Scopus16 WoS15 Europe PMC19
2017 Pagani, I. S., Kok, C. H., Saunders, V. A., Van der Hoek, M. B., Heatley, S. L., Schwarer, A. P., . . . Ross, D. M. (2017). A method for next-generation sequencing of paired diagnostic and remission Samples to detect mitochondrial DNA mutations associated with leukemia. The Journal of molecular diagnostics : JMD, 19(5), 711-721.
DOI Scopus7 WoS6 Europe PMC7
2016 Ebrahimie, E., Moussavi Nik, S., Newman, M., Van Der Hoek, M., & Lardelli, M. (2016). The Zebrafish equivalent of Alzheimer's disease-associated PRESENILIN Isoform PS2V regulates inflammatory and other responses to hypoxic stress. Journal of Alzheimer's Disease, 52(2), 581-608.
DOI Scopus18 WoS15 Europe PMC16
2015 Tse, E., Helbig, K., Van der Hoek, K., McCartney, E., Van der Hoek, M., George, J., & Beard, M. (2015). Fatty acids induce a pro-inflammatory gene expression profile in Huh-7 cells that attenuates the anti-HCV action of interferon. Journal of Interferon and Cytokine Research, 35(5), 392-400.
DOI Scopus18 WoS17 Europe PMC13
2015 Mahdi, L., Van der Hoek, M., Ebrahimie, E., Paton, J., & Ogunniyi, A. (2015). Characterization of pneumococcal genes involved in bloodstream invasion in a mouse model. PLoS One, 10(11), e0141816-1-e0141816-15.
DOI Scopus20 WoS20 Europe PMC20
2014 Pham, D., Powell, J., Gliddon, B., Moretti, P., Tsykin, A., Van der Hoek, M., . . . Pitson, S. (2014). Enhanced expression of transferrin receptor 1 contributes to oncogenic signalling by sphingosine kinase 1. Oncogene, 33(48), 5559-5568.
DOI Scopus27 WoS26 Europe PMC26
2014 Hummel, R., Sie, C., Watson, D. I., Wang, T., Ansar, A., Michael, M. Z., . . . Hussey, D. J. (2014). MicroRNA signatures in chemotherapy resistant esophageal cancer cell lines. WORLD JOURNAL OF GASTROENTEROLOGY, 20(40), 14904-14912.
DOI WoS69 Europe PMC64
2013 Brotherton, P., Haak, W., Templeton, J., Soubrier, J., Adler, C., Richards, S., . . . Cooper, A. (2013). Neolithic mitochondrial haplogroup H genomes and the genetic origins of Europeans. Nature Communications, 4(1764), 1-11.
DOI Scopus195 WoS184 Europe PMC132
2013 Humphreys, K. J., Cobiac, L., Le Leu, R. K., Van der Hoek, M. B., & Michael, M. Z. (2013). Histone deacetylase inhibition in colorectal cancer cells reveals competing roles for members of the oncogenic miR-17-92 cluster. Molecular Carcinogenesis, 52(6), 459-474.
DOI Scopus105 WoS91 Europe PMC82
2012 Ogunniyi, A., Mahdi, L., Trappetti, C., Verhoeven, N., Mermans, D., Van der Hoek, M., . . . Paton, J. (2012). Identification of genes that contribute to the pathogenesis of invasive Pneumococcal Disease by in vivo transcriptomic analysis. Infection and Immunity, 80(9), 3268-3278.
DOI Scopus56 WoS51 Europe PMC49
2012 Gagliardi, L., Ling, K., Kok, C., Carolan, J., Brautigan, P., Kenyon, R., . . . Scott, H. (2012). Genome-wide gene expression profiling identifies overlap with malignant adrenocortical tumours and novel mechanisms of inefficient steroidogenesis in familial ACTH-independent macronodular adrenal hyperplasia. Endocrine-Related Cancer, 19(3), 19-23.
DOI Scopus6 WoS6 Europe PMC5
2012 Mahdi, L., Wang, H., Van der Hoek, M., Paton, J., & Ogunniyi, A. (2012). Identification of a novel pneumococcal vaccine antigen preferentially expressed during meningitis in mice. Journal of Clinical Investigation, 122(6), 2208-2220.
DOI Scopus46 WoS43 Europe PMC46
2012 Moghaddami, M., Mayrhofer, G., Anderson, P., Morris, H., Van der Hoek, M., & Cleland, L. (2012). Efficacy and mechanisms of action of vitamin D in experimental polyarthritis. Immunology and Cell Biology, 90(2), 168-177.
DOI Scopus19 WoS19 Europe PMC17
2011 Pomie, C., Vicente, R., Vuddamalay, Y., Lundgren, B., Van der Hoek, M., Enault, G., . . . van Meerwijk, J. (2011). Autoimmune regulator (AIRE)-deficient CD8(+)CD28(low) regulatory T lymphocytes fail to control experimental colitis. Proceedings of the National Academy of Sciences of the United States of America, 108(30), 12437-12442.
DOI Scopus18 WoS18 Europe PMC17
2011 Knelangen, J., Van der Hoek, M., Kong, W., Owens, J., Fischer, B., & Santos, A. (2011). MicroRNA expression profile during adipogenic differentiation in mouse embryonic stem cells. Physiological Genomics, 43(10), 611-620.
DOI Scopus16 WoS14 Europe PMC15
2011 Bastian, I., Tam Tam, S., Zhou, X., Kazenwadel, J., Van Der Hoek, M., Michael, M., . . . Haberberger, R. (2011). Differential expression of microRNA-1 in dorsal root ganglion neurons. Histochemistry and Cell Biology, 135(1), 37-45.
DOI Scopus17 WoS16 Europe PMC17
2011 Hummel, R., Wang, T., Watson, D. I., Michael, M. Z., Van der Hoek, M., Haier, J., & Hussey, D. J. (2011). Chemotherapy-induced modification of microRNA expression in esophageal cancer. ONCOLOGY REPORTS, 26(4), 1011-1017.
DOI WoS85 Europe PMC80
2010 Ogunniyi, A., Mahdi, L., Jennings, M., McEwan, A., McDevitt, C., Van der Hoek, M., . . . Paton, J. (2010). Central role of manganese in regulation of stress responses, physiology, and metabolism in Streptococcus pneumoniae. Journal of Bacteriology, 192(17), 4489-4497.
DOI Scopus89 WoS85 Europe PMC85
2010 King, M., Reeve, W., Van Der Hoek, M. B., Williams, N., McComb, J., O'Brien, P. A., & Hardy, G. E. S. J. (2010). Defining the phosphite-regulated transcriptome of the plant pathogen Phytophthora cinnamomi. Molecular Genetics and Genomics, 284(6), 425-435.
DOI Scopus60 WoS56 Europe PMC34
2010 Neal, C. S., Michael, M. Z., Rawlings, L. H., Van der Hoek, M. B., & Gleadle, J. M. (2010). The VHL-dependent regulation of microRNAs in renal cancer. BMC MEDICINE, 8(1), 17 pages.
DOI WoS153 Europe PMC140
2009 Tea, M., Fogarty, R., Brereton, H., Michael, M., Van der Hoek, M., Tsykin, A., . . . Williams, K. (2009). Gene expression microarray analysis of early oxygen-induced retinopathy in the rat. Journal of Ocular Biology, Diseases, and Informatics, 2(4), 190-201.
DOI Scopus14 Europe PMC10
2009 Ohlsson Teague, E., Van Der Hoek, K., Van der Hoek, M., Perry, N., Wagaarachchi, P., Robertson, S., . . . Hull, M. (2009). MicroRNA-regulated pathways associated with endometriosis. Molecular Endocrinology, 23(2), 265-275.
DOI Scopus345 WoS327 Europe PMC294
2009 Howlett, M., Giraud, A. S., Lescesen, H., Jackson, C. B., Kalantzis, A., Van Driel, I. R., . . . Judd, L. M. (2009). The Interleukin-6 Family Cytokine Interleukin-11 Regulates Homeostatic Epithelial Cell Turnover and Promotes Gastric Tumor Development. Gastroenterology, 136(3), 967-9e3.
DOI Scopus87 WoS83 Europe PMC78

Date Role Committee Institution Country
2023 - ongoing Assistant Treasurer Australasian Genomic Technologies Association The University of Adelaide Australia
2014 - 2023 Treasurer Australasian Genomics Technologies Assosiation South Australian Health and Medical Research Institute Australia
2011 - 2014 Treasurer Australasian Genomic Technologies Association SA Pathology Australia
2009 - 2011 Treasurer Australasian Microarray and Associated Technolgies Association SA Pathology Australia
2005 - 2009 Board Member Australasian Microarray and Associated Technologies Association SA Pathology Australia

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