Marie-Claire Seeley

Teaching Strengths

Clinical autonomic assessment and skills
Nursing research and evidence-based practice
Research theory and study design
Consumer and community engagement
Cardiovascular and autonomic physiology

Dr Marie-Claire Seeley

Ext-Funded Research Fellow (C

School of Nursing and Midwifery

College of Health

Eligible to supervise Masters and PhD (as Co-Supervisor) - email supervisor to discuss availability.

Available For Media Comment.


Dr Marie-Claire Seeley (RN, PhD) is a Senior Research Fellow at the Rosemary Bryant AO Research Centre, Adelaide University, a Churchill Fellow, and recipient of the 2025 South Australian Science Excellence and Innovation PhD Award. Her research explores autonomic contributions to women's cardiovascular disease, spanning postural orthostatic tachycardia syndrome (POTS), long COVID, spontaneous coronary artery dissection, vasospastic angina, and connective tissue disorders, with a focus on conditions that disproportionately affect women and remain poorly explained by conventional cardiovascular models.
 
Dr Seeley conceived and leads Australia's first national POTS registry and findings have informed national and international health policy and parliamentary inquiries. She has a strong track record in health translation, clinical guideline development, and consumer advocacy, and has contributed to government submissions and health system reform across multiple jurisdictions.
 
As founding CEO of the Australian POTS Foundation, Dr Seeley is committed to improving recognition, diagnosis, and care for people living with cardiac dysautonomia and related women's cardiovascular conditions.

My research program centres on autonomic dysfunction and its consequences for quality of life, care, and health outcomes in conditions that disproportionately affect women. I established Australia's first national POTS registry, which has underpinned a series of studies examining quality of life, symptom burden, and patient experience in POTS, including the first Australian data quantifying how severely the condition affects daily functioning compared to healthy populations.

My program spans quantitative and qualitative methodologies. Quantitative work includes physiological studies of cerebral hypoperfusion in POTS, autonomic dysfunction in long COVID, and early investigations into autonomic contributions to spontaneous coronary artery dissection and vasospastic angina. Qualitative work has centred on patient experience, capturing the diagnostic journey, barriers to care, and the lived impact of under-recognised cardiovascular conditions.

A significant body of work has focused on long COVID, where my research was the first globally to characterise autonomic nervous system damage in this population as mechanistically comparable to POTS, contributing to national and international case definitions and policy responses.

Across all streams, knowledge translation is a core research value. Registry findings have been converted into clinical guidelines, GP education programs, and consumer resources, with a particular focus on bridging the gap between emerging evidence and frontline clinical practice.

Date Position Institution name
2024 - ongoing Senior Research Fellow Adelaide University
2021 - ongoing CEO The Australian POTS Foundation

Date Type Title Institution Name Country Amount
2026 Fellowship Department of Health Sponsored Winston Churchill Fellowship 2025 Winston Churchill Trust Australia -
2025 Award SA Science Excellence and Innovation Awards outh Australian Department of State Development Australia 10000
2025 Award Cardiovascular Society of Australia and New Zealand Cardiovascular Nursing Prize Cardiovascular Society of Australia and New Zealand Australia -
2024 Award Rising Star PhD Clinical and Medical Science Award Heart Foundation- SACVRN Australia -
2024 Scholarship EO Myers Travel Scholarship Heart Foundation Australia 3000

Date Institution name Country Title
2021 - 2024 University of Adelaide Australia PhD
Monash University Australia Master of Nursing
Monash University Australia Graduate Certificate in Emergency Nursing
Royal Melbourne Institute of Technology University Australia Bachelor of Nursing

Year Citation
2026 Lau, D. H., Fedorowski, A., Raj, S. R., Schild, C., Pace, L. A., Blitshteyn, S., . . . Gallagher, C. (2026). Postural Orthostatic Tachycardia Syndrome: A State-of-the-Art Review. Heart Lung and Circulation, 35(2), 171-185.
DOI Scopus2 WoS3 Europe PMC2
2026 Wilson, G., Gallagher, C., Schild, C., McCaffrey, N., Lau, D. H., & Seeley, M. -C. (2026). Patient Perspectives on Multidisciplinary Management of Postural Orthostatic Tachycardia Syndrome (POTS): Insights from Real-World Experience.. Eur J Cardiovasc Nurs, 4 pages.
DOI
2026 Fountain, J., McWhorter, T. J., Seeley, M. -C., Bindoff, A. D., Handley, K., Hewings, R., & Hazel, S. J. (2026). Heart rate variability and behaviour in dogs during and after scent work. Applied Animal Behaviour Science, 299, 106986-1-106986-10.
DOI
2026 Luo, S., Zheng, Z., Karimi, L., Plebanski, M., Lankatillake, C., Sheahan, J., . . . Itsiopoulos, C. (2026). Between silence and solutions: a global guideline review of long COVID care and services in Australia. BMC Health Services Research, 26(1), 604-1-604-20.
DOI
2026 Seeley, M. -C., Gallagher, C., Wilson, G., Bailey, D., Langdon, A., Ong, E., . . . Stavrakis, S. (2026). Comparative Analysis of Circulating Cytokines and Adrenergic Autoantibodies in Postural Orthostatic Tachycardia Syndrome, Postacute Sequelae of SARS-CoV-2, and Healthy Controls.. Journal of the American Heart Association, e048615.
DOI
2025 Seeley, M. -C., O'Brien, H., Wilson, G., Coat, C., Smith, T., Hickson, K., . . . Lau, D. H. (2025). Novel brain SPECT imaging unravels abnormal cerebral perfusion in patients with postural orthostatic tachycardia syndrome and cognitive dysfunction.. Scientific Reports, 15(1), 3487-1-3487-9.
DOI Scopus5 WoS3
2025 Seeley, M. -C., Wilson, G., Ong, E., Langdon, A., Chieng, J., Bailey, D., . . . Gallagher, C. (2025). Biological sex-dependent differences in postural orthostatic tachycardia syndrome (POTS).. Eur J Cardiovasc Nurs, 24(5), 762-771.
DOI Scopus2 WoS3 Europe PMC4
2025 Wilson, G., Seeley, M. -C., Slater, P., Lau, D. H., & Gallagher, C. (2025). Characterising Postural Orthostatic Tachycardia Syndrome (POTS) triggered by a viral illness compared to concussion or trauma. . Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 35(4), 637-641.
DOI
2025 Seeley, M. C., Wilson, G., Ong, E., Langdon, A., Chieng, J., Bailey, D., . . . Gallagher, C. (2025). Symptom burden, quality of life, and diagnostic journey of people with postural orthostatic tachycardia syndrome, Australia, 2021–24: a descriptive patient registry data study. Medical Journal of Australia, 223(3), 159-160.
DOI Scopus4 WoS3 Europe PMC2
2025 Seeley, M. -C., Hooper, M., Tan, J., Wells, R., Gallagher, C., & Lau, D. H. (2025). Plasma exchange improves cognitive function in long-COVID related postural orthostatic tachycardia syndrome and autoimmune neurological dysfunction. American Journal of Medicine, 138(1), 153-154.
DOI Scopus3 WoS3 Europe PMC5
2024 Seeley, M. -C., Gallagher, C., & Lau, D. H. (2024). Emerging Role of Autonomic Modulation by Transcutaneous Vagus Nerve Stimulation: Electrifying Hope in POTS?. JACC Clin Electrophysiol, 10(2), 356-358.
DOI Scopus1 WoS1 Europe PMC1
2024 Seeley, M. -C., O'Brien, H., Gallagher, C., Schild, C., & Lau, D. H. (2024). Autonomic dysfunction in post-acute sequelae of COVID-19. European Journal of Internal Medicine, 127, 161-163.
DOI Scopus1 WoS1 Europe PMC1
2023 Seeley, M. -C., Gallagher, C., Ong, E., Langdon, A., Chieng, J., Bailey, D., . . . Lau, D. H. (2023). Poor health-related quality of life in postural orthostatic tachycardia syndrome in comparison with a sex- and age-matched normative population.. Clinical Autonomic Research, 33(4), 469-477.
DOI Scopus22 WoS24 Europe PMC18
2023 Seeley, M. -C., Gallagher, C., Ong, E., Langdon, A., Chieng, J., Bailey, D., . . . Lau, D. H. (2023). High incidence of autonomic dysfunction and postural orthostatic tachycardia syndrome in patients with long-COVID: Implications for management and healthcare planning. The American Journal of Medicine, 138(2), 354-361.e1.
DOI Scopus50 WoS48 Europe PMC51
2023 Seeley, M. -C., Gallagher, C., Colman, F., & Lau, D. H. (2023). Impact of Long-COVID on Australian Sufferers: Implications for Healthcare Planning. Heart, Lung and Circulation, 32(10), e76-e77.
DOI Scopus6 WoS4 Europe PMC4
2023 Seeley, M. -C., Lau, D. H., & Gallagher, C. (2023). Postural Orthostatic Tachycardia Syndrome: Diagnosis and Management Guide for Nurses. Nursing: Research and Reviews, Volume 13, 41-49.
DOI WoS2
2022 Malik, V., Nguyen, M. T., Seeley, M. C., Thiyagarajah, A., Elliott, A. D., Arnolda, L. F., . . . Lau, D. H. (2022). Abnormal Cardiac Remodeling in Postural Orthostatic Tachycardia Syndrome: Further Insights Into its Cardiac Origin. JACC: Clinical Electrophysiology, 8(8), 1044-1046.
DOI Scopus2 WoS1 Europe PMC2
2021 Seeley, M. -C., & Lau, D. H. (2021). Raising the bar in postural orthostatic tachycardia syndrome research: Evidence and challenges. Autonomic Neuroscience, 233, 102790.
DOI Scopus5 WoS5 Europe PMC4
2021 Seeley, M. -C., Thynne, T. R., Braund, W. J., Worthley, D. L., Gallagher, C., Sanders, P., & Lau, D. H. (2021). Desmopressin as a novel long-term treatment in postural tachycardia syndrome patients with polyuria. The American Journal of Medicine, 134(9), e486-e487.
DOI Scopus2 WoS2 Europe PMC2
2015 Seeley, M. C., McKenna, L., & Hood, K. (2015). Graduate nurses' knowledge of the functions and limitations of pulse oximetry. Journal of Clinical Nursing, 24(23-24), 3538-3549.
DOI Scopus12 WoS11 Europe PMC7

Year Citation
2024 Seeley, M. -C. (2024). Paradigm Shift: The Lived Experience of a Researcher with Postural Orthostatic Tachycardia Syndrome. In Research Partners with Lived Experience (pp. 1-16). Springer Nature Singapore.
DOI

Year Citation
2024 Seeley, M. C., Gallagher, C., Wilson, G., Page, A., & Lau, D. H. (2024). Autonomic dysfunction is prevalent in PASC of Covid-19 [PASC]. In EUROPEAN JOURNAL OF CARDIOVASCULAR NURSING Vol. 23 (pp. I125). OXFORD UNIV PRESS.
DOI

Year Citation
2026 Seeley, M. -C., Tran, D. X. A., Marathe, J. A., Sharma, S., Wilson, G., Atkins, S., . . . Psaltis, P. J. (2026). Antecedent autonomic symptoms predict contemporary autonomic symptom burden and reduced health-related quality of life after spontaneous coronary artery dissection.
DOI

FUNDING SUPPORT

2025               MRFF | Scalable Allied Health and General Practitioner Responses to Long-COVID | $2,998,859 AUD

2024                MRFF | Emerging from the long shadow | $4,999,855 AUD

2024                MRFF | HEAL | $249,893 AUD

2024                Heart Foundation | Tom Simpson Equipment Grant | $15,000 AUD

2024                EO Meyers Travel Fellowship $3,000 AUD

2024                CSANZ ACNAP Travel Fellowship $5,000 AUD

2023                Dysautonomia International Research Grant $100,000 USD

2021                Australian Government Research Training Program Scholarship

2021                Standing up to POTS – Research Grant- 100,000 USD

 

 

Date Role Research Topic Program Degree Type Student Load Student Name
2025 Co-Supervisor Novel INfluential Factors in the natural histOry of Non-Obstructive Coronary Artery disease syndrome (INFO-NOCA) study Doctor of Philosophy Doctorate Full Time Ms Alex Tran
2025 Co-Supervisor Novel INfluential Factors in the natural histOry of Non-Obstructive Coronary Artery disease syndrome (INFO-NOCA) study - Doctorate Full Time Ms Alex Tran

Date Role Research Topic Location Program Supervision Type Student Load Student Name
2025 - ongoing Co-Supervisor Novel INfluential Factors in the natural histOry of Non-Obstructive Coronary Artery diseases (INFO-NOCA) The University of Adelaide Medicine Doctorate Full Time Dang Xuan Anh Tran
2021 - 2022 Principal Supervisor Association of gastrointestinal dysfunction and health related quality of life in postural orthostatic tachycardia syndrome University of Adelaide - Honours Full Time Annabelle Dennis
2021 - ongoing Co-Supervisor Exploring the lived experience of those with postural orthostatic tachycardia syndrome diagnostic odyssey: a qualitative study University of Adelaide - Honours Full Time Erin Welford

Date Role Board name Institution name Country
2022 - ongoing Founder The Australian POTS Foundation The Australian POTS Foundation Australia
2021 - ongoing Director Board of Directors The Australian POTS Foundation Australia

Date Role Committee Institution Country
2026 - ongoing Member Research Advisory Committee Heart Foundation Australia
2025 - ongoing Member ME/CFS Guideline Devleopment Committee NHMRC Australia

Date Event Name Event Type Institution Country
2024 - 2024 ISAN 2024 Conference International Society of Autonomic Neuroscience -
2024 - 2024 ISAN 2024 Conference International Society of Autonomic Neuroscience United Kingdom
2024 - 2024 Association of Cardiovascular Nursing and Allied Health 2024 Conference ACNAP -
2021 - 2024 ACRA 2023 Plenary or general session Australian Cardiovascular Rehabilitation Association Australia

Date Topic Presented at Institution Country
2022 - 2022 POTS Unmasked - South Australian Health and Medical Research Institute Australia

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