Marie-Claire Seeley

Marie-Claire Seeley

Adelaide Medical School

Faculty of Health and Medical Sciences

Eligible to supervise Masters and PhD (as Co-Supervisor) - email supervisor to discuss availability.

Dr Marie-Claire Seeley (RN, PhD) is a Post-Doctoral Fellow at the University of Adelaide. With a perspective as a researcher with 'lived experience,' she has dedicated her research efforts to exploring postural orthostatic tachycardia syndrome (POTS). Her significant contributions include the establishment of the only Australian patient registry for POTS, which currently holds more than 500 registrants. Dr. Seeley's research work has elucidated the prevalence of autonomic nervous system disorders in post-acute sequelae of COVID-19 (PASC). Her work has also been instrumental in quantifying reduced quality of life compared to age- and sex-matched populations in PASC and POTS.
As the CEO of the Australian POTS Foundation, Dr. Seeley has successful advocated for the adoption of a unique International Disease Code for POTS in Australia. She also serves as a member of the Long COVID Collaboration and facilitator of the ADARC Long COVID Consumer and Community Advisory Committee. Dr. Seeley continues to make significant contributions to the field of autonomic nursing, driving forward research, advocacy, and policy changes to improve outcomes for individuals affected by cardiac dysautonomia.

Marie-Claire is a Post-Doctoral Research Fellow at the University of Adelaide where she is exploring the association between autonomic and cardiac disease. Marie-Claire has utilised her own 25 years of personal experience with postural orthostatic tachycardia syndrome [POTS] and hypermobile Ehlers Danlos Syndrome [hEDS] to contribute to research in this domain.  She has a keen interest in reducing time to diagnosis in female dominated cardiac disorders and in collaborating in research that focuses on improving outcomes for those living with POTS other non obstructive cardiac conditions. 

She is passionate about translating this work into her clinical practice as a dysautonomia practice nurse at an Adelaide POTS clinic.  It is here that she utilises her clinical, educational and research skills to provide a multidisciplinary clinic for those with POTS and other similar post viral syndromes. 

  • Journals
    Year Citation
    2025 Seeley, M. -C., O'Brien, H., Wilson, G., Coat, C., Smith, T., Hickson, K., . . . Lau, D. H. (2025). Novel brain SPECT imaging unravels abnormal cerebral perfusion in patients with postural orthostatic tachycardia syndrome and cognitive dysfunction.. Sci Rep, 15(1), 3487.
    DOI
    2025 Seeley, M. -C., Wilson, G., Ong, E., Langdon, A., Chieng, J., Bailey, D., . . . Gallagher, C. (2025). Biological sex-dependent differences in postural orthostatic tachycardia syndrome. EUROPEAN JOURNAL OF CARDIOVASCULAR NURSING, 10 pages.
    DOI
    2025 Seeley, M. -C., Hooper, M., Tan, J., Wells, R., Gallagher, C., & Lau, D. H. (2025). Plasma exchange improves cognitive function in long-COVID related postural orthostatic tachycardia syndrome and autoimmune neurological dysfunction. American Journal of Medicine, 138(1), 153-154.
    DOI Scopus1 Europe PMC2
    2024 Seeley, M. -C., O'Brien, H., Gallagher, C., Schild, C., & Lau, D. H. (2024). Autonomic dysfunction in post-acute sequelae of COVID-19. European Journal of Internal Medicine, 127, 161-163.
    DOI
    2024 Seeley, M. -C., Gallagher, C., & Lau, D. H. (2024). Emerging Role of Autonomic Modulation by Transcutaneous Vagus Nerve Stimulation: Electrifying Hope in POTS?. JACC Clin Electrophysiol, 10(2), 356-358.
    DOI
    2023 Seeley, M. C., Gallagher, C., Ong, E., Langdon, A., Chieng, J., Bailey, D., . . . Lau, D. H. (2023). Poor health-related quality of life in postural orthostatic tachycardia syndrome in comparison with a sex- and age-matched normative population. Clinical Autonomic Research, 33(4), 469-477.
    DOI Scopus9 Europe PMC8
    2023 Seeley, M. -C., Gallagher, C., Ong, E., Langdon, A., Chieng, J., Bailey, D., . . . Lau, D. H. (2023). High incidence of autonomic dysfunction and postural orthostatic tachycardia syndrome in patients with long-COVID: Implications for management and healthcare planning. The American Journal of Medicine, 138(2), 354-361.e1.
    DOI Scopus23 Europe PMC26
    2023 Seeley, M. -C., Gallagher, C., Colman, F., & Lau, D. H. (2023). Impact of Long-COVID on Australian Sufferers: Implications for Healthcare Planning. Heart, Lung and Circulation, 32(10), e76-e77.
    DOI Scopus3 Europe PMC2
    2023 Seeley, M. -C., Lau, D. H., & Gallagher, C. (2023). Postural Orthostatic Tachycardia Syndrome: Diagnosis and Management Guide for Nurses. Nursing: Research and Reviews, Volume 13, 41-49.
    DOI
    2022 Malik, V., Nguyen, M. T., Seeley, M. C., Thiyagarajah, A., Elliott, A. D., Arnolda, L. F., . . . Lau, D. H. (2022). Abnormal Cardiac Remodeling in Postural Orthostatic Tachycardia Syndrome: Further Insights Into its Cardiac Origin. JACC: Clinical Electrophysiology, 8(8), 1044-1046.
    DOI Scopus1 Europe PMC1
    2021 Seeley, M. -C., & Lau, D. H. (2021). Raising the bar in postural orthostatic tachycardia syndrome research: Evidence and challenges. Autonomic Neuroscience, 233, 102790.
    DOI Scopus2 WoS1 Europe PMC2
    2021 Seeley, M. -C., Thynne, T. R., Braund, W. J., Worthley, D. L., Gallagher, C., Sanders, P., & Lau, D. H. (2021). Desmopressin as a novel long-term treatment in postural tachycardia syndrome patients with polyuria. The American Journal of Medicine, 134(9), e486-e487.
    DOI Scopus1 WoS1 Europe PMC1
    2015 Seeley, M. C., McKenna, L., & Hood, K. (2015). Graduate nurses' knowledge of the functions and limitations of pulse oximetry. Journal of clinical nursing, 24(23-24), 3538-3549.
    DOI Scopus11 WoS7 Europe PMC4

  • Book Chapters
    Year Citation
    2024 Seeley, M. -C. (2024). Paradigm Shift: The Lived Experience of a Researcher with Postural Orthostatic Tachycardia Syndrome. In Research Partners with Lived Experience (pp. 1-16). Springer Nature Singapore.
    DOI

  • Conference Papers
    Year Citation
    2024 Seeley, M. C., Gallagher, C., Wilson, G., Page, A., & Lau, D. H. (2024). Autonomic dysfunction is prevalent in PASC of Covid-19 [PASC]. In EUROPEAN JOURNAL OF CARDIOVASCULAR NURSING Vol. 23 (pp. I125). OXFORD UNIV PRESS.
    DOI

FUNDING SUPPORT

2024                MRFF | Emerging from the long shadow | $4999855.75 AUD

2024                MRFF | HEAL | $249893.20 AUD

2024                EO Meyers Travel Fellowship $3000

2024                CSANZ ACNAP Travel Fellowship $5000

2023                Dysautonomia International Research Grant 100 000 USD

2022                Adelaide Medical School/Biomedicine Research Travel Awards $1200

2021                Australian Government Research Training Program Scholarship

2021                Standing up to POTS – Research Grant- 100 000 USD

2021                Awesome Foundation - $1000 grant

 

Marie-Claire supervisors honours and masters students through varying University of Adelaide programs. 

  • Other Supervision Activities
    Date Role Research Topic Location Program Supervision Type Student Load Student Name
    2021 - 2022 Principal Supervisor Association of gastrointestinal dysfunction and health related quality of life in postural orthostatic tachycardia syndrome University of Adelaide - Honours Full Time Annabelle Dennis
    2021 - ongoing Co-Supervisor Exploring the lived experience of those with postural orthostatic tachycardia syndrome diagnostic odyssey: a qualitative study University of Adelaide - Honours Full Time Erin Welford

  • Board Memberships
    Date Role Board name Institution name Country
    2022 - ongoing Founder The Australian POTS Foundation The Australian POTS Foundation Australia

  • Event Participation
    Date Event Name Event Type Institution Country
    2024 - 2024 ISAN 2024 Conference International Society of Autonomic Neuroscience -
    2024 - 2024 ISAN 2024 Conference International Society of Autonomic Neuroscience United Kingdom
    2024 - 2024 Association of Cardiovascular Nursing and Allied Health 2024 Conference ACNAP -
    2021 - 2024 ACRA 2023 Plenary or general session Australian Cardiovascular Rehabilitation Association Australia

  • Presentation
    Date Topic Presented at Institution Country
    2022 - 2022 POTS Unmasked - South Australian Health and Medical Research Institute Australia
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