Dr Marie-Claire Seeley
Ext-Funded Research Fellow (C
School of Nursing and Midwifery
College of Health
Eligible to supervise Masters and PhD (as Co-Supervisor) - email supervisor to discuss availability.
Dr Marie-Claire Seeley (RN, PhD) is a Senior Research Fellow at the Rosemary Bryant AO Research Centre, Adelaide University, a Churchill Fellow, and recipient of the 2025 South Australian Science Excellence and Innovation PhD Award. Her research explores autonomic contributions to women's cardiovascular disease, spanning postural orthostatic tachycardia syndrome (POTS), long COVID, spontaneous coronary artery dissection, vasospastic angina, and connective tissue disorders, with a focus on conditions that disproportionately affect women and remain poorly explained by conventional cardiovascular models.
Dr Seeley conceived and leads Australia's first national POTS registry and findings have informed national and international health policy and parliamentary inquiries. She has a strong track record in health translation, clinical guideline development, and consumer advocacy, and has contributed to government submissions and health system reform across multiple jurisdictions.
As founding CEO of the Australian POTS Foundation, Dr Seeley is committed to improving recognition, diagnosis, and care for people living with cardiac dysautonomia and related women's cardiovascular conditions.
My research program centres on autonomic dysfunction and its consequences for quality of life, care, and health outcomes in conditions that disproportionately affect women. I established Australia's first national POTS registry, which has underpinned a series of studies examining quality of life, symptom burden, and patient experience in POTS, including the first Australian data quantifying how severely the condition affects daily functioning compared to healthy populations.
My program spans quantitative and qualitative methodologies. Quantitative work includes physiological studies of cerebral hypoperfusion in POTS, autonomic dysfunction in long COVID, and early investigations into autonomic contributions to spontaneous coronary artery dissection and vasospastic angina. Qualitative work has centred on patient experience, capturing the diagnostic journey, barriers to care, and the lived impact of under-recognised cardiovascular conditions.
A significant body of work has focused on long COVID, where my research was the first globally to characterise autonomic nervous system damage in this population as mechanistically comparable to POTS, contributing to national and international case definitions and policy responses.
Across all streams, knowledge translation is a core research value. Registry findings have been converted into clinical guidelines, GP education programs, and consumer resources, with a particular focus on bridging the gap between emerging evidence and frontline clinical practice.
| Date | Position | Institution name |
|---|---|---|
| 2024 - ongoing | Senior Research Fellow | Adelaide University |
| 2021 - ongoing | CEO | The Australian POTS Foundation |
| Date | Type | Title | Institution Name | Country | Amount |
|---|---|---|---|---|---|
| 2026 | Fellowship | Department of Health Sponsored Winston Churchill Fellowship 2025 | Winston Churchill Trust | Australia | - |
| 2025 | Award | SA Science Excellence and Innovation Awards | outh Australian Department of State Development | Australia | 10000 |
| 2025 | Award | Cardiovascular Society of Australia and New Zealand Cardiovascular Nursing Prize | Cardiovascular Society of Australia and New Zealand | Australia | - |
| 2024 | Award | Rising Star PhD Clinical and Medical Science Award | Heart Foundation- SACVRN | Australia | - |
| 2024 | Scholarship | EO Myers Travel Scholarship | Heart Foundation | Australia | 3000 |
| Date | Institution name | Country | Title |
|---|---|---|---|
| 2021 - 2024 | University of Adelaide | Australia | PhD |
| Monash University | Australia | Master of Nursing | |
| Monash University | Australia | Graduate Certificate in Emergency Nursing | |
| Royal Melbourne Institute of Technology University | Australia | Bachelor of Nursing |
| Year | Citation |
|---|---|
| 2026 | Lau, D. H., Fedorowski, A., Raj, S. R., Schild, C., Pace, L. A., Blitshteyn, S., . . . Gallagher, C. (2026). Postural Orthostatic Tachycardia Syndrome: A State-of-the-Art Review. Heart Lung and Circulation, 35(2), 171-185. Scopus2 WoS3 Europe PMC2 |
| 2026 | Wilson, G., Gallagher, C., Schild, C., McCaffrey, N., Lau, D. H., & Seeley, M. -C. (2026). Patient Perspectives on Multidisciplinary Management of Postural Orthostatic Tachycardia Syndrome (POTS): Insights from Real-World Experience.. Eur J Cardiovasc Nurs, 4 pages. |
| 2026 | Fountain, J., McWhorter, T. J., Seeley, M. -C., Bindoff, A. D., Handley, K., Hewings, R., & Hazel, S. J. (2026). Heart rate variability and behaviour in dogs during and after scent work. Applied Animal Behaviour Science, 299, 106986-1-106986-10. |
| 2026 | Luo, S., Zheng, Z., Karimi, L., Plebanski, M., Lankatillake, C., Sheahan, J., . . . Itsiopoulos, C. (2026). Between silence and solutions: a global guideline review of long COVID care and services in Australia. BMC Health Services Research, 26(1), 604-1-604-20. |
| 2026 | Seeley, M. -C., Gallagher, C., Wilson, G., Bailey, D., Langdon, A., Ong, E., . . . Stavrakis, S. (2026). Comparative Analysis of Circulating Cytokines and Adrenergic Autoantibodies in Postural Orthostatic Tachycardia Syndrome, Postacute Sequelae of SARS-CoV-2, and Healthy Controls.. Journal of the American Heart Association, e048615. |
| 2025 | Seeley, M. -C., O'Brien, H., Wilson, G., Coat, C., Smith, T., Hickson, K., . . . Lau, D. H. (2025). Novel brain SPECT imaging unravels abnormal cerebral perfusion in patients with postural orthostatic tachycardia syndrome and cognitive dysfunction.. Scientific Reports, 15(1), 3487-1-3487-9. Scopus5 WoS3 |
| 2025 | Seeley, M. -C., Wilson, G., Ong, E., Langdon, A., Chieng, J., Bailey, D., . . . Gallagher, C. (2025). Biological sex-dependent differences in postural orthostatic tachycardia syndrome (POTS).. Eur J Cardiovasc Nurs, 24(5), 762-771. Scopus2 WoS3 Europe PMC4 |
| 2025 | Wilson, G., Seeley, M. -C., Slater, P., Lau, D. H., & Gallagher, C. (2025). Characterising Postural Orthostatic Tachycardia Syndrome (POTS) triggered by a viral illness compared to concussion or trauma. . Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 35(4), 637-641. |
| 2025 | Seeley, M. C., Wilson, G., Ong, E., Langdon, A., Chieng, J., Bailey, D., . . . Gallagher, C. (2025). Symptom burden, quality of life, and diagnostic journey of people with postural orthostatic tachycardia syndrome, Australia, 2021–24: a descriptive patient registry data study. Medical Journal of Australia, 223(3), 159-160. Scopus4 WoS3 Europe PMC2 |
| 2025 | Seeley, M. -C., Hooper, M., Tan, J., Wells, R., Gallagher, C., & Lau, D. H. (2025). Plasma exchange improves cognitive function in long-COVID related postural orthostatic tachycardia syndrome and autoimmune neurological dysfunction. American Journal of Medicine, 138(1), 153-154. Scopus3 WoS3 Europe PMC5 |
| 2024 | Seeley, M. -C., Gallagher, C., & Lau, D. H. (2024). Emerging Role of Autonomic Modulation by Transcutaneous Vagus Nerve Stimulation: Electrifying Hope in POTS?. JACC Clin Electrophysiol, 10(2), 356-358. Scopus1 WoS1 Europe PMC1 |
| 2024 | Seeley, M. -C., O'Brien, H., Gallagher, C., Schild, C., & Lau, D. H. (2024). Autonomic dysfunction in post-acute sequelae of COVID-19. European Journal of Internal Medicine, 127, 161-163. Scopus1 WoS1 Europe PMC1 |
| 2023 | Seeley, M. -C., Gallagher, C., Ong, E., Langdon, A., Chieng, J., Bailey, D., . . . Lau, D. H. (2023). Poor health-related quality of life in postural orthostatic tachycardia syndrome in comparison with a sex- and age-matched normative population.. Clinical Autonomic Research, 33(4), 469-477. Scopus22 WoS24 Europe PMC18 |
| 2023 | Seeley, M. -C., Gallagher, C., Ong, E., Langdon, A., Chieng, J., Bailey, D., . . . Lau, D. H. (2023). High incidence of autonomic dysfunction and postural orthostatic tachycardia syndrome in patients with long-COVID: Implications for management and healthcare planning. The American Journal of Medicine, 138(2), 354-361.e1. Scopus50 WoS48 Europe PMC51 |
| 2023 | Seeley, M. -C., Gallagher, C., Colman, F., & Lau, D. H. (2023). Impact of Long-COVID on Australian Sufferers: Implications for Healthcare Planning. Heart, Lung and Circulation, 32(10), e76-e77. Scopus6 WoS4 Europe PMC4 |
| 2023 | Seeley, M. -C., Lau, D. H., & Gallagher, C. (2023). Postural Orthostatic Tachycardia Syndrome: Diagnosis and Management Guide for Nurses. Nursing: Research and Reviews, Volume 13, 41-49. WoS2 |
| 2022 | Malik, V., Nguyen, M. T., Seeley, M. C., Thiyagarajah, A., Elliott, A. D., Arnolda, L. F., . . . Lau, D. H. (2022). Abnormal Cardiac Remodeling in Postural Orthostatic Tachycardia Syndrome: Further Insights Into its Cardiac Origin. JACC: Clinical Electrophysiology, 8(8), 1044-1046. Scopus2 WoS1 Europe PMC2 |
| 2021 | Seeley, M. -C., & Lau, D. H. (2021). Raising the bar in postural orthostatic tachycardia syndrome research: Evidence and challenges. Autonomic Neuroscience, 233, 102790. Scopus5 WoS5 Europe PMC4 |
| 2021 | Seeley, M. -C., Thynne, T. R., Braund, W. J., Worthley, D. L., Gallagher, C., Sanders, P., & Lau, D. H. (2021). Desmopressin as a novel long-term treatment in postural tachycardia syndrome patients with polyuria. The American Journal of Medicine, 134(9), e486-e487. Scopus2 WoS2 Europe PMC2 |
| 2015 | Seeley, M. C., McKenna, L., & Hood, K. (2015). Graduate nurses' knowledge of the functions and limitations of pulse oximetry. Journal of Clinical Nursing, 24(23-24), 3538-3549. Scopus12 WoS11 Europe PMC7 |
| Year | Citation |
|---|---|
| 2024 | Seeley, M. -C. (2024). Paradigm Shift: The Lived Experience of a Researcher with Postural Orthostatic Tachycardia Syndrome. In Research Partners with Lived Experience (pp. 1-16). Springer Nature Singapore. DOI |
| Year | Citation |
|---|---|
| 2024 | Seeley, M. C., Gallagher, C., Wilson, G., Page, A., & Lau, D. H. (2024). Autonomic dysfunction is prevalent in PASC of Covid-19 [PASC]. In EUROPEAN JOURNAL OF CARDIOVASCULAR NURSING Vol. 23 (pp. I125). OXFORD UNIV PRESS. DOI |
| Year | Citation |
|---|---|
| 2026 | Seeley, M. -C., Tran, D. X. A., Marathe, J. A., Sharma, S., Wilson, G., Atkins, S., . . . Psaltis, P. J. (2026). Antecedent autonomic symptoms predict contemporary autonomic symptom burden and reduced health-related quality of life after spontaneous coronary artery dissection. DOI |
FUNDING SUPPORT
2025 MRFF | Scalable Allied Health and General Practitioner Responses to Long-COVID | $2,998,859 AUD
2024 MRFF | Emerging from the long shadow | $4,999,855 AUD
2024 MRFF | HEAL | $249,893 AUD
2024 Heart Foundation | Tom Simpson Equipment Grant | $15,000 AUD
2024 EO Meyers Travel Fellowship $3,000 AUD
2024 CSANZ ACNAP Travel Fellowship $5,000 AUD
2023 Dysautonomia International Research Grant $100,000 USD
2021 Australian Government Research Training Program Scholarship
2021 Standing up to POTS – Research Grant- 100,000 USD
| Date | Role | Research Topic | Program | Degree Type | Student Load | Student Name |
|---|---|---|---|---|---|---|
| 2025 | Co-Supervisor | Novel INfluential Factors in the natural histOry of Non-Obstructive Coronary Artery disease syndrome (INFO-NOCA) study | Doctor of Philosophy | Doctorate | Full Time | Ms Alex Tran |
| 2025 | Co-Supervisor | Novel INfluential Factors in the natural histOry of Non-Obstructive Coronary Artery disease syndrome (INFO-NOCA) study | - | Doctorate | Full Time | Ms Alex Tran |
| Date | Role | Research Topic | Location | Program | Supervision Type | Student Load | Student Name |
|---|---|---|---|---|---|---|---|
| 2025 - ongoing | Co-Supervisor | Novel INfluential Factors in the natural histOry of Non-Obstructive Coronary Artery diseases (INFO-NOCA) | The University of Adelaide | Medicine | Doctorate | Full Time | Dang Xuan Anh Tran |
| 2021 - 2022 | Principal Supervisor | Association of gastrointestinal dysfunction and health related quality of life in postural orthostatic tachycardia syndrome | University of Adelaide | - | Honours | Full Time | Annabelle Dennis |
| 2021 - ongoing | Co-Supervisor | Exploring the lived experience of those with postural orthostatic tachycardia syndrome diagnostic odyssey: a qualitative study | University of Adelaide | - | Honours | Full Time | Erin Welford |
| Date | Role | Board name | Institution name | Country |
|---|---|---|---|---|
| 2022 - ongoing | Founder | The Australian POTS Foundation | The Australian POTS Foundation | Australia |
| 2021 - ongoing | Director | Board of Directors | The Australian POTS Foundation | Australia |
| Date | Role | Committee | Institution | Country |
|---|---|---|---|---|
| 2026 - ongoing | Member | Research Advisory Committee | Heart Foundation | Australia |
| 2025 - ongoing | Member | ME/CFS Guideline Devleopment Committee | NHMRC | Australia |
| Date | Event Name | Event Type | Institution | Country |
|---|---|---|---|---|
| 2024 - 2024 | ISAN 2024 | Conference | International Society of Autonomic Neuroscience | - |
| 2024 - 2024 | ISAN 2024 | Conference | International Society of Autonomic Neuroscience | United Kingdom |
| 2024 - 2024 | Association of Cardiovascular Nursing and Allied Health 2024 | Conference | ACNAP | - |
| 2021 - 2024 | ACRA 2023 | Plenary or general session | Australian Cardiovascular Rehabilitation Association | Australia |
| Date | Topic | Presented at | Institution | Country |
|---|---|---|---|---|
| 2022 - 2022 | POTS Unmasked | - | South Australian Health and Medical Research Institute | Australia |
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