Marc Gladman

Dr Marc Gladman

Adelaide Medical School

Faculty of Health and Medical Sciences

Eligible to supervise Masters and PhD - email supervisor to discuss availability.

Professor Marc A Gladman PhD MBBS DFFP MRCOG MRCS FRCS (Gen Surg) FRACS

Marc is a surgeon scientist and the Chair of the Section of Academic Surgery and Academic Surgery Committee of the Royal Australasian College of Surgeons. He is also the Chair of the Surgical Research Society of Australasia and was previously co-convener of the “Developing a Career and Skills in Academic Surgery”. He has served in advisory roles for the National Health Performance Agency, the Cancer Institute of NSW, Cancer Australia and the Australian Commission on Safety and Quality in Health Care.

He received his degree in Medicine from King’s College in the UK and was awarded a PhD by the University of London and then went on to complete a NIHR lectureship. He trained in both obstetrics and gynaecology and general surgery in the UK, receiving his Fellowship in 2008. Previously, he held the position of Chair of Colorectal Surgery at the University of Sydney.

Marc's clinical research spans patient-orientated and population-based themes. Each year more than 230 million major operations are performed worldwide, one for every 25 people in the world. Diseases of the bowel are among the commonest in the population, with bowel cancer being the second most common type of newly diagnosed cancer in Australia and the second biggest cancer killer. it is unclear how many operations are performed for bowel problems in Australia each year and what results are achieved following surgery.

He also runs an enteric neuroscience laboratory focused at exploring the complex interaction between the intrinsic and extrinsic innervation of the gut and relating aberrations of the enteric and autonomic nervous systems to disturbances in gastrointestinal function leading to bowel problems such as constipation and incontinence, which each affect approximately 1 in 10 people.

Marc is a passionate and inspirational educator and has authored 10 textbooks, including the highly acclaimed “Examination Surgery: A Guide to Passing the FRACS in General Surgery” and “Clinical Cases and OSCEs in Surgery”, which has won recognition at international book awards. He is a member of the Academy of Surgical Educators and the Adelaide Education Academy and previously was the Director of the Medical Program at the University of Adelaide.

Marc's abiding research interest is understanding large bowel function in health and disease and its application to improve the care of the surgical patient. His research program includes integration of clinical and laboratory themes, the former spanning each of the three NIH categories of clinical research:

  1. Health outcomes research to objectively measure the impact of surgical interventions in patients with gastrointestinal disease in New South Wales.
  2. Population-based research to investigate the epidemiological basis of gastrointestinal diseases;
  3. Patient-orientated research involving measurement of gastrointestinal physiological function to allow the development of novel therapies; and
  4. T1 enteric neuroscience research aimed at better understanding the brain gut axis and its dysfunction in the clinical context of functional bowel disorders. Current studies are focused at exploring the complex interaction between the intrinsic and extrinsic innervation of the gut and relating aberrations of the enteric and autonomic nervous systems to disturbances in function.

Established collaborations:

National: Dept of Human Physiology, Flinders University, Adelaide; Menzies Centre for Health Policy; Centre for Virus Research, Westmead Institute, the University of Sydney

International: Dept of Cell & Molecular Biology, Nobel Institute, Karolinska Institute; Center for Health Outcomes & Policy, University of Michigan, USA.

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  • Journals
    Year Citation
    2020 Keane, C., Fearnhead, N., Bordeianou, L., Christensen, P., Espin Basany, E., Laurberg, S., . . . Skaife, P. (2020). International consensus definition of low anterior resection syndrome. Colorectal Disease, 22(3), 331-341.
    DOI
    2020 Keane, C., Fearnhead, N., Bordeianou, L., Christensen, P., Basany, E., Laurberg, S., . . . Skaife, P. (2020). International consensus definition of Low Anterior Resection Syndrome. Diseases of the Colon and Rectum, 63(3), 274-284.
    DOI Scopus1
    2020 Ng, K. -S., Russo, R., & Gladman, M. (2020). Colonic transit in patients after anterior resection: prospective, comparative study using single-photon emission CT/CT scintigraphy. The British Journal of Surgery, 107(5), 567-579.
    DOI
    2020 Ng, K. -S., & Gladman, M. A. (2020). Patient reported and physician recorded bowel dysfunction following colorectal resection and radical cystectomy: a prospective, comparative study. Colorectal Disease, OnlinePubl, 1-32.
    DOI
    2018 Ng, K., Montes-Adrian, N., Mahns, D., & Gladman, M. (2018). Quantification and neurochemical coding of the myenteric plexus in humans: no regional variation between the distal colon and rectum. Neurogastroenterology and Motility, 30(3), e13193-1-e13193-11.
    DOI Scopus1 WoS1
    2017 Mirbagheri, N., Hatton, S., Ng, K., Lagopoulos, J., & GLADMAN, M. (2017). Brain responses to mechanical rectal stimuli in patients with faecal incontinence: an fMRI study. Colorectal Disease, 19(10), 917-926.
    DOI Scopus2 WoS1 Europe PMC1
    2017 Ng, K., Nassar, N., Soares, D., Stewart, P., & Gladman, M. (2017). Acute lower gastrointestinal hemorrhage: outcomes and risk factors for intervention in 949 emergency cases. International Journal of Colorectal Disease, 32(9), 1327-1335.
    DOI Scopus2 WoS1
    2017 Siramanna, P., & Gladman, M. (2017). Development of a proficiency-based virtual reality simulation training curriculum for laparoscopic appendicectomy. ANZ Journal of Surgery, 87(10), 760-766.
    DOI Scopus6 WoS5 Europe PMC1
    2016 Whiteley, I., Russell, M., Nassar, N., & Gladman, M. (2016). Outcomes of support rod usage in loop stoma formation. International Journal of Colorectal Disease, 31(6), 1189-1195.
    DOI Scopus5 WoS5 Europe PMC3
    2016 Boyce, S., Nassar, N., Lee, C., Suen, M., Zahrani, S., & Gladman, M. (2016). Young-onset colorectal cancer in New South Wales: a population-based study. Medical Journal of Australia, 205(10), 465-470.
    DOI Scopus11 WoS13 Europe PMC2
    2016 Ng, K. -S., Brookes, S., Montes-Adrian, N., Mahns, D., & Gladman, M. (2016). Electrophysiological characterization of human rectal afferents. American Journal of Physiology - Gastrointestinal and Liver Physiology, 311(6), G1047-G1055.
    DOI Scopus4 WoS3 Europe PMC3
    2016 Mirbagheri, N., Dunn, G., Naganathan, V., Suen, M., & Gladman, M. (2016). Normal values and clinical use of bedside sonographic assessment of postoperative gastric emptying: a prospective cohort study. Diseases of the Colon and Rectum, 59(8), 758-765.
    DOI Scopus2 WoS1 Europe PMC1
    2016 Ng, K., Stewart, P., & Gladman, M. (2016). Postoperative lower gastrointestinal haemorrhage following bowel resection. ANZ Journal of Surgery, 86(10), 836-837.
    DOI
    2016 Mirbagheri, N., Sivakumaran, Y., Nassar, N., & Gladman, M. (2016). Systematic review of the impact of sacral neuromodulation on clinical symptoms and gastrointestinal physiology. ANZ Journal of Surgery, 86(4), 232-236.
    DOI Scopus3 WoS3 Europe PMC4
    2015 Windsor, J., Searle, J., Garrod, T., Hanney, R., Grigg, M., Smith, J., & Gladman, M. (2015). Developing an integrated training pathway for clinical academics: Notes from the first binational summit meeting. ANZ Journal of Surgery, 85(6), 398-399.
    DOI Scopus2 WoS2 Europe PMC1
    2015 Ng, K. -S., Nassar, N., Hamd, K., Nagarajah, A., & Gladman, M. (2015). Prevalence of functional bowel disorders and faecal incontinence: an Australian primary care survey. Colorectal Disease, 17(2), 150-159.
    DOI Scopus13 WoS14 Europe PMC11
    2015 Windsor, J., Searle, J., Hanney, R., Chapman, A., Grigg, M., Choong, P., . . . Gladman, M. (2015). Building a sustainable clinical academic workforce to meet the future healthcare needs of Australia and New Zealand: Report from the first summit meeting. Internal Medicine Journal, 45(9), 965-971.
    DOI Scopus8 WoS8 Europe PMC4
    2015 Ng, K. -S., Sivakumaran, Y., Nassar, N., & Gladman, M. (2015). Fecal incontinence: community prevalence and associated factors - A systematic review. Diseases of the Colon and Rectum, 58(12), 1194-1209.
    DOI Scopus55 WoS48 Europe PMC26
    2014 Palit, S., Bhan, C., Lunniss, P., Boyle, D., Gladman, M., Knowles, C., & Scott, S. (2014). Evacuation proctography: A reappraisal of normal variability. Colorectal Disease, 16(7), 538-546.
    DOI Scopus34 WoS32 Europe PMC20
    2013 Ng, K. -S., Stewart, P., & Gladman, M. (2013). Uncommon site for a common lesion. ANZ Journal of Surgery, 83(1-2), 88-89.
    DOI Scopus1
    2013 Wright, D., Ng, K. -S., Keshava, A., & Gladman, M. (2013). An unusual cause of large bowel obstruction. Colorectal Disease, 15(1), E60-E61.
    DOI
    2010 Sharma, N., Patel, M., Gladman, M., Ahmed, S., & Dorudi, S. (2010). Not one, but two, unexpected findings in a young man. The Lancet, 375(9726), 1664.
    DOI
    2009 Lunniss, P., Gladman, M., Benninga, M., & Rao, S. (2009). Pathophysiology of evacuation disorders. Neurogastroenterology and Motility, 21(SUPPL. 2), 31-40.
    DOI Scopus28 Europe PMC20
    2009 Brookes, S., Dinning, P., & Gladman, M. (2009). Neuroanatomy and physiology of colorectal function and defaecation: From basic science to human clinical studies. Neurogastroenterology and Motility, 21(SUPPL. 2), 9-19.
    DOI Scopus30 Europe PMC20
    2009 Sharma, N., Gladman, M., & Ahmed, S. (2009). Idiopathic necrotising fasciitis. BMJ Case Reports, 2009(mar08 1), bcr0920080924.
    DOI Scopus1
    2009 Gladman, M., Aziz, Q., Scott, S., Williams, N., & Lunniss, P. (2009). Rectal hyposensitivity: Pathophysiological mechanisms. Neurogastroenterology and Motility, 21(5), 508-e5.
    DOI Scopus26 Europe PMC20
    2008 Gladman, M., & Mukherjee, D. (2008). Electronic Clinical Challenges and Images in GI. Gastroenterology, 134(5), e4-e6.
    DOI
    2008 Gladman, M., Haq, A., & Davies, T. (2008). The syringe test to determine the integrity of intestinal anastomoses. Annals of the Royal College of Surgeons of England, 90(8), 696-703.
    DOI Scopus1
    2008 Gladman, M., & Sayer, G. (2008). Clinical Challenges and Images in GI. Gastroenterology, 134(5), 1294-1636.
    DOI Europe PMC1
    2008 Gladman, M., & Knowles, C. (2008). Novel concepts in the diagnosis, pathophysiology and management of idiopathic megabowel. Colorectal Disease, 10(6), 531-538.
    DOI Scopus30 Europe PMC20
    2008 Zarate, N., Knowles, C., Newell, M., Garvie, N., Gladman, M., Lunniss, P., & Scott, S. (2008). In patients with slow transit constipation, the pattern of colonic transit delay does not differentiate between those with and without impaired rectal evacuation. American Journal of Gastroenterology, 103(2), 427-434.
    DOI Scopus35 Europe PMC29
    2008 Gladman, M., & Knowles, C. (2008). Surgical Treatment of Patients with Constipation and Fecal Incontinence. Gastroenterology Clinics of North America, 37(3), 605-625.
    DOI Scopus24 WoS18 Europe PMC18
    2008 Scott, S., & Gladman, M. (2008). Manometric, Sensorimotor, and Neurophysiologic Evaluation of Anorectal Function. Gastroenterology Clinics of North America, 37(3), 511-538.
    DOI Scopus51 WoS39 Europe PMC32
    2007 Gladman, M., & Shami, S. (2007). Medical mystery - An unusual complication of colonoscopy. New England Journal of Medicine, 357(14), 1431.
    DOI Scopus4 Europe PMC1
    2007 Gladman, M., & Shami, S. (2007). Medical mystery: An unusual complication of colonoscopy - The answer [10]. New England Journal of Medicine, 357(22), 2309-2310.
    DOI Scopus1
    2007 Gladman, M., Dvorkin, L., Scott, S., Lunniss, P., & Williams, N. (2007). A novel technique to identify patients with megarectum. Diseases of the Colon and Rectum, 50(5), 621-629.
    DOI Scopus14 WoS14 Europe PMC7
    2007 Vasudevan, S., Scott, S., Gladman, M., & Lunniss, P. (2007). Rectal hyposensitivity: Evaluation of anal sensation in female patients with refractory constipation with and without faecal incontinence. Neurogastroenterology and Motility, 19(8), 660-667.
    DOI Scopus12 Europe PMC11
    2007 Murphy, J., Scott, S., Gladman, M., & Lunniss, P. (2007). Faecal incontinence (Br J Surg 2007; 94: 134-144) [1]. British Journal of Surgery, 94(6), 754.
    DOI
    2006 Gladman, M., Lunniss, P., Scott, S., & Swash, M. (2006). Rectal hyposensitivity. American Journal of Gastroenterology, 101(5), 1140-1151.
    DOI Scopus108 Europe PMC73
    2005 Dvorkin, L., Gladman, M., Scott, S., Williams, N., & Lunniss, P. (2005). Rectal intussusception: A study of rectal biomechanics and visceroperception. American Journal of Gastroenterology, 100(7), 1578-1585.
    DOI Scopus16 Europe PMC11
    2005 Gladman, M., Dvorkin, L., Lunniss, P., Williams, N., & Scott, S. (2005). Rectal hyposensitivity: A disorder of the rectal wall or the afferent pathway? An assessment using the barostat. American Journal of Gastroenterology, 100(1), 106-114.
    DOI Scopus60 Europe PMC48
    2005 Gladman, M., Williams, N., Scott, S., Ogunbiyi, O., & Lunniss, P. (2005). Medium-term results of vertical reduction rectoplasty and sigmoid colectomy for idiopathic megarectum. British Journal of Surgery, 92(5), 624-630.
    DOI Scopus22 Europe PMC13
    2005 Gladman, M., Scott, S., Lunniss, P., & Williams, N. (2005). Systematic review of surgical options for idiopathic megarectum and megacolon. Annals of Surgery, 241(4), 562-574.
    DOI Scopus71 WoS54 Europe PMC34
    2005 Dvorkin, L., Gladman, M., Epstein, J., Scott, S., Williams, N., & Lunniss, P. (2005). Rectal intussusception in symptomatic patients is different from that in asymptomatic volunteers. British Journal of Surgery, 92(7), 866-872.
    DOI Scopus62 Europe PMC47
    2005 Brinkmann, D., Gladman, M., Norman, S., & Lawton, F. (2005). Why do women still develop cancer of the cervix despite the existence of a national screening programme?. European Journal of Obstetrics and Gynecology and Reproductive Biology, 119(1), 123-124.
    DOI Scopus9 WoS8 Europe PMC8
    2004 Lunniss, P., Gladman, M., Hetzer, F., Williams, N., & Scott, S. (2004). Risk factors in acquired faecal incontinence. Journal of the Royal Society of Medicine, 97(3), 111-116.
    DOI Scopus74 Europe PMC49
    2004 Gladman, M., Knowles, C., Gladman, L., & Payne, J. (2004). Intra-operative culture in appendicitis: Traditional practice challenged. Annals of the Royal College of Surgeons of England, 86(3), 196-201.
    DOI Scopus38 Europe PMC22
    2003 Gladman, M., Scott, S., Williams, N., & Lunniss, P. (2003). Clinical and physiological findings, and possible aetiological factors of rectal hyposensitivity. British Journal of Surgery, 90(7), 860-866.
    DOI Scopus40 Europe PMC32
    2003 Gladman, M., Scott, S., Chan, C., Williams, N., & Lunniss, P. (2003). Rectal hyposensitivity: Prevalence and clinical impact in patients with intractable constipation and fecal incontinence. Diseases of the Colon and Rectum, 46(2), 238-246.
    DOI Scopus84 Europe PMC54
    2002 Gladman, M., MacDonald, D., Webster, J., Cook, T., & Williams, G. (2002). Renal cell carcinoma in pregnancy. Journal of the Royal Society of Medicine, 95(4), 199-201.
    DOI Scopus16 Europe PMC12
    2002 Haq, A., Tiwari, A., Gladman, M., & Mohanna, P. (2002). A simple technique of irrigating the abdomen and pelvis through an appendicectomy wound. Annals of the Royal College of Surgeons of England, 84(3), 211.
    2002 Gladman, M., Scott, S., Lunniss, P., & Williams, N. (2002). Strategy for the surgical management of patients with idiopathic megarectum and megacolon (Br J Surg 2001; 88: 1392-6) [1]. British Journal of Surgery, 89(5), 623.
    DOI
    2001 Gladman, M., Khullar, V., & Cardozo, L. (2001). First do no harm: Knowing when not to operate. Journal of Obstetrics and Gynaecology, 21(5), 538.
    DOI

  • Books
    Year Citation
    2017 Ramachandran, M., & Gladman, M. A. (2017). Clinical Cases and Osces in Surgery The Definitive Guide to Passing Examinations. Churchill Livingstone.
    2013 Young, C. J., & Gladman, M. A. (2013). Examination Surgery A Guide to Passing the Fellowship Examination in General Surgery. Elsevier Health Sciences.
    2005 Gladman, M. A., Scott, S. M., & Williams, N. S. (2005). An overview.
    DOI

  • Book Chapters
    Year Citation
    2020 Gladman, M. (2020). International Trials: Surgical Research Networks. In T. pawlik, & J. -A. Sosa (Eds.), Clinical Trials (3rd Edition ed., pp. 213-228). Cham, Switzerland: Springer.
    2018 Gladman, M. (2018). Idiopathic Megacolon & Megarectum. In M. R. B. Keighley, & N. S. Williams (Eds.), Surgery of the Anus, Rectum & Colon (4th Edition ed., pp. 355-376). CRC press.
    2015 Gladman, M. (2015). Vertical reduction rectoplasty. In R. O'Connell, R. Madoff, & M. Solomon (Eds.), Operative Surgery of the Colon, Rectum and Anus (pp. 665-671). CRC Press.
    2013 Gladman, M., & Williams, N. (2013). Managing the megarectum. In Reconstructive Surgery of the Rectum, Anus and Perineum (pp. 283-296 pages).
    DOI
    2011 Gladman, M., & Scott, S. (2011). Rectal barostat for sensory testing. In H. Parkman, R. McCallum, & S. Rao (Eds.), Gastrointestinal Motility Testing: Laboratory and Office Handbook (1st ed., pp. 209-222). SLACK.
    2005 Gladman, M., Scott, S., & Williams, N. (2005). An overview. In Complex Anorectal Disorders: Investigation and Management (pp. 547-594).
    DOI Scopus1

  • Conference Papers
    Year Citation
    2016 Soares, D., Koneru, S., Ng, K., & Gladman, M. (2016). FAECAL INCONTINENCE: KNOWLEDGE, SKILLS AND BARRIERS TO SPECIALIST REFERRAL AMONGST AUSTRALIAN PRIMARY HEALTHCARE PROVIDERS. In NEUROUROLOGY AND URODYNAMICS Vol. 35 (pp. S335-S336). Tokyo, JAPAN: WILEY-BLACKWELL.
    WoS1
    2013 Sivakumaran, Y., Ng, K., Bhan, C., Nassar, N., & Gladman, M. (2013). An evaluation of the colorectal cancer referral pathway and adherence to Australian guidelines in a tertiary referral centre. In JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Vol. 28 (pp. 144). WILEY-BLACKWELL.
    WoS1

  • Conference Items
    Year Citation
    2020 Stojanovic, M., Hall, K., Louise, J., & Gladman, M. A. (2020). Faecal incontinence: Identification and classification of phenotypes using contemporary, objective clinico-physiological parameters. Poster session presented at the meeting of NEUROGASTROENTEROLOGY AND MOTILITY. WILEY.
    2020 Stojanovic, M., Bunjo, Z., & Gladman, M. A. (2020). Validity of 3D high resolution anorectal manometry in the assessment of anal sphincter defects. Poster session presented at the meeting of NEUROGASTROENTEROLOGY AND MOTILITY. WILEY.

Medtronic Project Grant: $70,000 - 1 year                                                    2013

Karl Storz Research Grant: $180,000 - 3 years                                            2012-2015

Validity of a virtual reality simulation of laparoscopic appendicectomy:  Development a proficiency-based training curriculum. Position CIA

Teaching Interests

Marc's teaching interests focus on technology-enhanced learning and incorporation of modern effective active learning pedagogies. He was an early adopter of the flipped classroom and uses experiential, team-based learning and process oriented guided inquiry learning (POGIL) in the education of medical students and postgraduate surgical and research students. He is a member of the Academy of Surgical Educators. Marc supervises PhD, MPhil, Masters and Honours  students, as well as student projects and electives.

Postgraduate and Undergraduate Teaching

Marc co-ordinates courses in a diverse portfolio of health and medical science degree programs. Currently, he is the year 3 advisor in the MBBS program. He co-ordinates Anatomy Teaching in the MBBS program and is a tutor in Unit 3101A and B  - Scientific Basis of Medicine III. Recently, he designed and now co-ordinates Applied Clinical Anatomy (Anat Sc 3003) in the BHMSc. Previously, he coordinated Bachelor of Nursing 2005 & 2008: Biology of Human Disease and developed and designed the successful Surgical Masterclass and 3 course units for the Masters of Surgery at the University of Sydney.

Marc has written numerous surgical and career development books, including the highly acclaimed “Examination Surgery: A Guide to Passing the FRACS in General Surgery” and “Clinical Cases and OSCEs in Surgery: The Definitive Guide to Passing Examinations”, which is now in its third edition and has won recognition at the British Medical Association international book awards. He has also designed websites for surgical education: e.g. masterclass.surgery

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  • Current Higher Degree by Research Supervision (University of Adelaide)
    Date Role Research Topic Program Degree Type Student Load Student Name
    2019 Principal Supervisor Management of Patients with Faecal Incontinence in the 21st Century: Optimisation of Assessment and Surgical Treatment using Sacral Neuromodulation Doctor of Philosophy Doctorate Full Time Mr Marko Stojanovic
    2019 Co-Supervisor The microbiome-gut-brain axis in chemotherapy-induced cognitive impairment Doctor of Philosophy Doctorate Full Time Miss Courtney Brooke Subramaniam

  • Other Supervision Activities
    Date Role Research Topic Location Program Supervision Type Student Load Student Name
    2018 - ongoing Principal Supervisor Variation in Surgical Anatomy of Sacral Nerve Roots and their Relation to the Sacral Foramina: University of Adelaide — Honours — Mr Marko Stojanovic
    2018 - ongoing Principal Supervisor Detailed evaluation of the human pelvic floor and its innervation: a cadaveric and immunohistochemical study University of Adelaide — Honours — Dr Rasika Samaranayake
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  • Committee Memberships
    Date Role Committee Institution Country
    2017 - ongoing Chair Surgical Research Society of Australasia — —
    2015 - ongoing Vice-Chair Section of Academic Surgery, RACS — —

  • Memberships
    Date Role Membership Country
    2017 - ongoing Member Adelaide Education Academy Australia
    2017 - ongoing Member Academy of Surgical Educators —
    2014 - ongoing Member Section of Colon & Rectal Surgeons, RACS —
    2013 - ongoing Member Colorectal Surgical Society of Australia & New Zealand Australia

  • Consulting/Advisories
    Date Institution Department Organisation Type Country
    2015 - ongoing Cancer Australia National Cancer Control Indicators framework Health services and related —

  • Editorial Boards
    Date Role Editorial Board Name Institution Country
    2016 - ongoing Board Member Medical Journal of Australia — —
  • Phone: 83135035
  • Email: marc.gladman@adelaide.edu.au
  • Campus: North Terrace
  • Building: Adelaide Health and Medical Sciences Building, floor 4
  • Room: 4055
  • Org Unit: Adelaide Medical School
Connect With Me
External Profiles

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