Mahnaz Ramezanpour

Dr Mahnaz Ramezanpour

Grant-Funded Researcher (A)

Adelaide Medical School

Faculty of Health and Medical Sciences

Eligible to supervise Masters and PhD - email supervisor to discuss availability.

Dr Mahnaz Ramezanpour is a biomedical researcher that completed her PhD in medical biotechnology in 2015 at Flinders University, Australia and authored > 42 peer-reviewed articles and 1 book chapter.

Her research program largely focuses on evaluating causes of chronic rhinosinusitis (CRS), identifying new diagnostic markers and treatment strategies to the benefit of CRS patients. She collaborates widely in multidisciplinary teams of scientists, clinicians and industry partners to ensure a real-world impact of her work. She collaborated with two large biotech companies, investigating the effect of several of their commercial products on the mucosal barrier function. As lead investigator, her research has led to the development of new soon to be released medical treatments for CRS.

Recently, she is using the state-of-the-art stem cell and organoid technologies for establishing airway organoids. The stem cell based organoid technology allows the culturing and expansion of a patient’s own cells in vitro in order to test and select the most effective and least toxic drug combination. She has established and characterized the nasal organoids derived from CRS patients. She is using cells, macrophages, and clinical bacteria isolates from CRS patients to evaluate and compare the effective capacity and immune response pathways of infection in the nasal organoids. Her research focus is on developing effective treatments against CRS patients and translating them from the lab to real-life applications.

Available projects for HDR, Honours and 3rd Year students in 2022 include:
1) Investigating new therapeutic targets to personalise treatment for CRS patients with recurrent disease.
2) The use of nasal organoids as a valid alternative model for lung organoids.

 

Investigating new therapeutic targets to personalise treatment for CRS patients with recurrent disease.

The use of nasal organoids as a valid alternative model for lung organoids.

Date Project/ No. Investigators Funding Body Amount
2020 A personalised therapeutic plan for S. aureus

recalcitrant CRS

Professor Alkis Psaltis

Dr Mahnaz Ramezanpour

 The Garnett Passe and Rodney Williams Memorial Foundation $362,363
         
         
  • Demonstrator: Flinders University, 2011-2014

    Undergraduate demonstrating of first-year flinders biological topic

  • Tutor: Flinders University, 2012-2014

    Tutoring undergraduate students in the medical biochemistry department

  • Current Higher Degree by Research Supervision (University of Adelaide)
    Date Role Research Topic Program Degree Type Student Load Student Name
    2024 Principal Supervisor Bacteriophage therapy in CRS patient nasal wound healing Doctor of Philosophy Doctorate Full Time Mr Jordan Hall
    2023 Co-Supervisor Potential use of essential oils from ethno-medicinal plants in clinical research Doctor of Philosophy Doctorate Full Time Miss Sumeena Karki

  • Past Higher Degree by Research Supervision (University of Adelaide)
    Date Role Research Topic Program Degree Type Student Load Student Name
    2021 - 2023 Co-Supervisor Investigating Transcription Factors in the Human Airway Mucosal Immunoepigenetics of Chronic Inflammatory Disease Master of Philosophy (Surgery) Master Full Time Mr Harrison Burchill Bolt
    2019 - 2022 Co-Supervisor Effects of Pseudomonas aeruginosa exoproteins on nasal mucosal barrier in chronic rhinosinusitis Doctor of Philosophy Doctorate Full Time Mrs Jannatul Ferdoush Tuli
    2018 - 2020 Co-Supervisor Nasal mucus: friend or foe? The effect of mucus on mucosal barrier dysfunction in chronic rhinosinusitis Doctor of Philosophy Doctorate Full Time Dr Stephen Shih-Teng Kao

  • Other Supervision Activities
    Date Role Research Topic Location Program Supervision Type Student Load Student Name
    2023 - 2024 Principal Supervisor Influenza-A infection liberates bacteria from biofilms in Chronic rhinosinusitis leading to an increased inflammatory response University of Adelaide - Honours Full Time Jordan Hall
    2022 - 2023 Principal Supervisor Interleukin-33 Expression and Impact in Chronic Rhinosinusitis Airway Epithelial Cells in Response to Viral Infection University of Adelaide - Honours Full Time Dray Harrison

  • Committee Memberships
    Date Role Committee Institution Country
    2020 - ongoing Member BHI Management Committee meeting Basi Hetzel Institute Australia
    2018 - 2018 Member Women’s and Children’s Hospital (WCH) Foundation Research Grants Committee Women’s and Children’s Hospital (WCH) Australia
    2018 - ongoing Member Woodcutters Road Environmental Protection Association Woodcutters Road Environmental Protection Association Australia
    2015 - ongoing Member Astronomical Society of Flinders University Astronomical Society of Flinders University Australia
  • Position: Grant-Funded Researcher (A)
  • Phone: 0882226524
  • Email: mahnaz.ramezanpour@adelaide.edu.au
  • Campus: North Terrace
  • Building: TQEH - Basil Hetzel Institute
  • Org Unit: Surgical Specialities
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