Mr Luke Gierus
Higher Degree by Research Candidate
PhD Candidate
School of Biomedicine
Faculty of Health and Medical Sciences
Luke Gierus is a Doctor of Philosophy student at the University of Adelaide. He is currently supervised by Professor Paul Thomas and Dr. Owain Edwards.
The focus of Luke's research is to develop strategies to facilitate in the humane suppression of invasive rodents through modification of naturally-occurring meiotic drive systems.
Luke's research is centred around developing novel gene drive methods to humanely suppress invasive rodent populations. These strategies utilise CRISPR/Cas9 and the t haplotype system to create a gene drive while investigating control strategies.
Luke also has a keen interest in modifying and improving CRISPR/Cas9 and similar systems including prime editing.
Members of the Genome Editing Laboratory, 2020: Ashleigh Geiger, Dr Gelshan Godahewa, Ya-han Kang, Joshua Chey, Professor Paul Thomas, Michaela Scherer, Jayshen Arudkumar, Dr Chandran Pfitzner, Caleb Lushington, Luke Gierus, Melissa White, Sandra Sandra Piltz, Dr Mark Bunting,
Not pictured: Dr Fatwa Adikusuma, Dr Stefka Tahseva.
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Language Competencies
Language Competency English Can read, write, speak, understand spoken and peer review -
Education
Date Institution name Country Title 2019 - 2019 The University of Adelaide Australia Bachelor of Science (Honours) 2016 - 2018 The University of Adelaide Australia Bachelor of Science (Advanced) -
Certifications
Date Title Institution name Country 2017 Faculty of Sciences Outstanding Academic Achievement Award The University of Adelaide - 2016 Faculty of Sciences Outstanding Academic Achievement Award The University of Adelaide - -
Research Interests
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Journals
Year Citation 2022 Bunting, M. D., Pfitzner, C., Gierus, L., White, M., Piltz, S., & Thomas, P. Q. (2022). Generation of Gene Drive Mice for Invasive Pest Population Suppression. Methods in molecular biology (Clifton, N.J.), 2495, 203-230.
Scopus2 Europe PMC12022 Gierus, L., Birand, A., Bunting, M. D., Godahewa, G. I., Piltz, S. G., Oh, K. P., . . . Thomas, P. Q. (2022). Leveraging a natural murine meiotic drive to suppress invasive populations. Proceedings of the National Academy of Sciences of USA, 119(46), 1-11.
Scopus3 WoS1 Europe PMC32021 Adikusuma, F., Lushington, C., Arudkumar, J., Godahewa, G. I., Chey, Y. C. J., Gierus, L., . . . Thomas, P. Q. (2021). Optimized nickase- and nuclease-based prime editing in human and mouse cells. Nucleic Acids Research, 49(18), 10785-10795.
Scopus21 WoS16 Europe PMC13- Gierus, L., Birand, A., Bunting, M. D., Godahewa, G. I., Piltz, S. G., Oh, K. P., . . . Thomas, P. Q. (n.d.). Leveraging a natural murine meiotic drive to suppress invasive populations.
- Adikusuma, F., Lushington, C., Arudkumar, J., Godahewa, G. I., Chey, Y. C. J., Gierus, L., . . . Thomas, P. Q. (n.d.). Optimized nickase- and nuclease-based prime editing in human and mouse cells.
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