Dr Loretta Chin
NHMRC Postdoctoral Research Officer (A)
Faculty of Health and Medical Sciences
Dr Loretta Chin is a postdoctoral research officer within the Reproductive Immunology laboratory at The University of Adelaide’s, Robinson Research Institute. Since completing her PhD at The University of Adelaide in 2014, under the supervision of Professors Sarah Robertson and Jeremy Thompson, focusing on the impact of an inflammatory peri-conceptual environment on the developing embryo, Loretta has continued her postdoctoral training within the Robertson laboratory where she now investigates immune pathways as potential targets to prevent inflammation and infection induced preterm birth. Her recent work has identified the TLR4 pathway as being critical in controlling the inflammatory activation that precedes preterm and normal term delivery.
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Appointments
Date Position Institution name 2014 - ongoing Postdoctoral Research Officer University of Adelaide -
Language Competencies
Language Competency English Can read, write, speak, understand spoken and peer review Malay Can read, write, speak and understand spoken -
Education
Date Institution name Country Title 2014 University of Adelaide Adelaide PhD 2008 University of Adelaide Adelaide B. Sc. (Hons) 2007 University of Adelaide Adelaide B.Sc. (Biotechnology)
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Journals
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Book Chapters
Year Citation 2015 Robertson, S., Chin, P. -Y., Schjenken, J., & Thompson, J. (2015). Female tract cytokines and developmental programming in embryos. In H. Leese, & D. Brison (Eds.), Cell signalling during mammalian early embryo development (Vol. 843, 1 ed., pp. 173-213). New York: Springer.
Scopus30 WoS27 Europe PMC10 -
Conference Papers
Year Citation 2019 Groome, H. M., Care, A. S., Chin, P. Y., Roberts, C. T., & Robertson, S. A. (2019). Macrophage Regulation of Decidual Vascular Remodelling is Crucial for Pregnancy Success in Mice.. In REPRODUCTIVE SCIENCES Vol. 26 (pp. 202A). Paris, FRANCE: SAGE PUBLICATIONS INC. 2019 Kieffer, E. C., Chin, P. Y., Green, E. S., Moldenhauer, L. M., Prins, J. R., & Robertson, S. A. (2019). Prednisolone Treatment in Early Pregnancy Disrupts Maternal Immune Adaptation and Alters Pregnancy Outcomes in Mice.. In REPRODUCTIVE SCIENCES Vol. 26 (pp. 291A-292A). Paris, FRANCE: SAGE PUBLICATIONS INC. 2016 Green, E., Moldenhauer, L. M., Kara, E. E., Chin, P. Y., Robker, R. L., McColl, S. R., & Robertson, S. A. (2016). Progesterone control of regulatory T cell phenotype and abundance in pregnancy - A novel role for non-classical progesterone action. In JOURNAL OF REPRODUCTIVE IMMUNOLOGY Vol. 115 (pp. 43). Erfurt, GERMANY: ELSEVIER IRELAND LTD.
2011 Chin, P. Y., Thompson, J. G., & Robertson, S. A. (2011). Maternal Interleukin-10 Deficiency Increases Sensitivity to Adverse Programming Effects of a Low Dose LPS Insult in the Pre-Implantation Period.. In BIOLOGY OF REPRODUCTION Vol. 85 (pp. 2 pages). Portland, OR: SOC STUDY REPRODUCTION. 2010 Chin, P. Y., Thompson, J. G., & Robertson, S. A. (2010). Programming embryo development with a pre-implantation inflammatory insult. In JOURNAL OF REPRODUCTIVE IMMUNOLOGY Vol. 86 (pp. 39). Palm Grove, AUSTRALIA: ELSEVIER IRELAND LTD.
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Conference Items
Year Citation 2017 Nadeau-Vallee, M., Chin, P. -Y., Belarbi, L., Brien, M. -E., Pundir, S., Beaudry-Richard, A., . . . Chemtob, S. (2017). Antenatal Suppression of Interleukin-1 Protects Against Inflammation-Induced Fetal Injury and Improves Neonatal and Developmental Outcomes in Mice.. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. Orlando, FL: SAGE PUBLICATIONS INC. 2017 Nadeau-Vallee, M., Chin, P. -Y., Belarbi, L., Brien, M. -E., Pundir, S., Berryer, M. H., . . . Chemtob, S. (2017). PROTECTIVE EFFECT OF A NOVEL NONCOMPETITIVE IL-1 RECEPTOR-BIASED LIGAND IN AN INFECTION-AND INFLAMMATION-INDUCED PRETERM BIRTH AS WELL AS IN FETAL INJURY AND DEVELOPMENTAL OUTCOMES. Poster session presented at the meeting of ACTA PAEDIATRICA. WILEY. 2016 Green, E. S., Moldenhauer, L. M., Kara, E. E., Chin, P. Y., Robker, R. L., McColl, S. R., & Robertson, S. A. (2016). Regulatory T cell abundance and phenotype in pregnancy - a novel role for progesterone potentially independent of nuclear progesterone receptor. Poster session presented at the meeting of EUROPEAN JOURNAL OF IMMUNOLOGY. Melbourne, AUSTRALIA: WILEY-BLACKWELL. 2014 Robertson, S. A., Gomez-Lopez, N., Diener, K., Bijland, M. T., Chin, P. -Y., & Olson, D. M. (2014). Essential Role for Macrophages in Late Gestation Pregnancy to Prevent Spontaneous Preterm Birth in Mice. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. Florence, ITALY: SAGE PUBLICATIONS INC. 2014 Robertson, S. A., Chin, P. -Y., Dorian, C., & Hutchinson, M. (2014). Inhibition of the TLR4 Signalling Pathway Protects Mice from LPS-Induced Preterm Delivery. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. Florence, ITALY: SAGE PUBLICATIONS INC. -
Figures
Year Citation - Chin, L., Dorian, C., Hutchinson, M., & Robertson, S. (n.d.). Toll-like receptor-4 antagonist (+)-naloxone elicits sexually dimorphic attenuation of inflammation-induced fetal programming in mice. Supplemental Figure 1.
- Chin, L., Dorian, C., Hutchinson, M., & Robertson, S. (n.d.). Effect of Toll-like receptor-4 antagonist (+)-naloxone and LPS challenge on gestation length, litter size and early post-natal survival and growth..
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Current Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2022 Co-Supervisor Early life origins of autoimmunity Doctor of Philosophy Doctorate Full Time Miss Stacey Jasmin Savin -
Past Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2017 - 2021 Co-Supervisor The role of macrophages in vascular adaptation to pregnancy in mice Doctor of Philosophy Doctorate Full Time Miss Holly Michelle Groome
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