NHMRC Postdoctoral Research Officer (A)
School of Biomedicine
Faculty of Health and Medical Sciences
Eligible to supervise Masters and PhD - email supervisor to discuss availability.
Dr Loretta Chin is a postdoctoral research officer within the Reproductive Immunology laboratory at The University of Adelaide’s, Robinson Research Institute. Since completing her PhD at The University of Adelaide in 2014, under the supervision of Professors Sarah Robertson and Jeremy Thompson, focusing on the impact of an inflammatory peri-conceptual environment on the developing embryo, Loretta has continued her postdoctoral training within the Robertson laboratory where she now investigates immune pathways as potential targets to prevent inflammation and infection induced preterm birth. Her recent work has identified the TLR4 pathway as being critical in controlling the inflammatory activation that precedes preterm and normal term delivery.
Date Position Institution name 2014 - ongoing Postdoctoral Research Officer University of Adelaide
Language Competency English Can read, write, speak, understand spoken and peer review Malay Can read, write, speak and understand spoken
Date Institution name Country Title 2014 University of Adelaide Adelaide PhD 2008 University of Adelaide Adelaide B. Sc. (Hons) 2007 University of Adelaide Adelaide B.Sc. (Biotechnology)
Year Citation 2015 Robertson, S., Chin, P. -Y., Schjenken, J., & Thompson, J. (2015). Female tract cytokines and developmental programming in embryos. In H. Leese, & D. Brison (Eds.), Cell signalling during mammalian early embryo development (Vol. 843, 1 ed., pp. 173-213). New York: Springer.
DOI Scopus29 WoS26 Europe PMC10
Year Citation 2019 Groome, H. M., Care, A. S., Chin, P. Y., Roberts, C. T., & Robertson, S. A. (2019). Macrophage Regulation of Decidual Vascular Remodelling is Crucial for Pregnancy Success in Mice.. In REPRODUCTIVE SCIENCES Vol. 26 (pp. 202A). Paris, FRANCE: SAGE PUBLICATIONS INC. 2019 Kieffer, E. C., Chin, P. Y., Green, E. S., Moldenhauer, L. M., Prins, J. R., & Robertson, S. A. (2019). Prednisolone Treatment in Early Pregnancy Disrupts Maternal Immune Adaptation and Alters Pregnancy Outcomes in Mice.. In REPRODUCTIVE SCIENCES Vol. 26 (pp. 291A-292A). Paris, FRANCE: SAGE PUBLICATIONS INC. 2016 Green, E., Moldenhauer, L. M., Kara, E. E., Chin, P. Y., Robker, R. L., McColl, S. R., & Robertson, S. A. (2016). Progesterone control of regulatory T cell phenotype and abundance in pregnancy - A novel role for non-classical progesterone action. In JOURNAL OF REPRODUCTIVE IMMUNOLOGY Vol. 115 (pp. 43). Erfurt, GERMANY: ELSEVIER IRELAND LTD.
2011 Chin, P. Y., Thompson, J. G., & Robertson, S. A. (2011). Maternal Interleukin-10 Deficiency Increases Sensitivity to Adverse Programming Effects of a Low Dose LPS Insult in the Pre-Implantation Period.. In BIOLOGY OF REPRODUCTION Vol. 85 (pp. 2 pages). Portland, OR: SOC STUDY REPRODUCTION. 2010 Chin, P. Y., Thompson, J. G., & Robertson, S. A. (2010). Programming embryo development with a pre-implantation inflammatory insult. In JOURNAL OF REPRODUCTIVE IMMUNOLOGY Vol. 86 (pp. 39). Palm Grove, AUSTRALIA: ELSEVIER IRELAND LTD.
Year Citation 2017 Nadeau-Vallee, M., Chin, P. -Y., Belarbi, L., Brien, M. -E., Pundir, S., Beaudry-Richard, A., . . . Chemtob, S. (2017). Antenatal Suppression of Interleukin-1 Protects Against Inflammation-Induced Fetal Injury and Improves Neonatal and Developmental Outcomes in Mice.. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. Orlando, FL: SAGE PUBLICATIONS INC. 2017 Nadeau-Vallee, M., Chin, P. -Y., Belarbi, L., Brien, M. -E., Pundir, S., Berryer, M. H., . . . Chemtob, S. (2017). PROTECTIVE EFFECT OF A NOVEL NONCOMPETITIVE IL-1 RECEPTOR-BIASED LIGAND IN AN INFECTION-AND INFLAMMATION-INDUCED PRETERM BIRTH AS WELL AS IN FETAL INJURY AND DEVELOPMENTAL OUTCOMES. Poster session presented at the meeting of ACTA PAEDIATRICA. WILEY. 2016 Green, E. S., Moldenhauer, L. M., Kara, E. E., Chin, P. Y., Robker, R. L., McColl, S. R., & Robertson, S. A. (2016). Regulatory T cell abundance and phenotype in pregnancy - a novel role for progesterone potentially independent of nuclear progesterone receptor. Poster session presented at the meeting of EUROPEAN JOURNAL OF IMMUNOLOGY. Melbourne, AUSTRALIA: WILEY-BLACKWELL. 2014 Robertson, S. A., Gomez-Lopez, N., Diener, K., Bijland, M. T., Chin, P. -Y., & Olson, D. M. (2014). Essential Role for Macrophages in Late Gestation Pregnancy to Prevent Spontaneous Preterm Birth in Mice. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. Florence, ITALY: SAGE PUBLICATIONS INC. 2014 Robertson, S. A., Chin, P. -Y., Dorian, C., & Hutchinson, M. (2014). Inhibition of the TLR4 Signalling Pathway Protects Mice from LPS-Induced Preterm Delivery. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. Florence, ITALY: SAGE PUBLICATIONS INC.
Year Citation Chin, L., Dorian, C., Hutchinson, M., & Robertson, S. (n.d.). Toll-like receptor-4 antagonist (+)-naloxone elicits sexually dimorphic attenuation of inflammation-induced fetal programming in mice. Supplemental Figure 1.
Chin, L., Dorian, C., Hutchinson, M., & Robertson, S. (n.d.). Effect of Toll-like receptor-4 antagonist (+)-naloxone and LPS challenge on gestation length, litter size and early post-natal survival and growth..
Current Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2022 Co-Supervisor The overarching aim of my research project is to investigate the impact of viral-induced inflammation around the time of conception on fetal and offspring immune programming and to identify if the offspring are more susceptible to auto-inflammatory conditions in later life Doctor of Philosophy Doctorate Full Time Miss Stacey Jasmin Savin
Past Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2017 - 2021 Co-Supervisor The role of macrophages in vascular adaptation to pregnancy in mice Doctor of Philosophy Doctorate Full Time Miss Holly Michelle Groome
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