Ms Linh Mai

Higher Degree by Research Candidate

School of Medicine

College of Health


I completed my PhD in Medicine at the University of Adelaide, based in the School of Medicine and the Centre for Translational Pathway Research. My research focused on the tumour microbiome in head and neck cancer, particularly how tumour-associated bacteria influence microbial adaptation, cancer biology, and treatment response.
My doctoral work investigated head and neck cancer-associated Streptococcus using bacterial genomics, microbiology, cancer cell biology, and transcriptomic analysis. Through this work, I examined how these bacteria adapt to the tumour microenvironment, respond to chemotherapy, and modulate cancer cell responses to treatment.
More broadly, my research interests include cancer biology, tumour microbiology, host–microbe interactions, chemotherapy resistance, multi-omics analysis, and translational cancer research. My work combines wet-lab experimentation and computational biology, with the long-term goal of translating microbiome research into clinically relevant strategies for cancer care.

Date Position Institution name
2022 - ongoing Higher Research Candidate University of Adelaide

Language Competency
Chinese (Mandarin) Can speak and understand spoken
English Can read, write, speak, understand spoken and peer review
Vietnamese Can read, write, speak, understand spoken and peer review

Date Institution name Country Title
2022 University of Adelaide Australia PhD
2020 - 2021 University of Adelaide Australia Master of Biomedical
Ho Chi Minh City University of Technology Vietnam Bachelor of Biotechnology

Year Citation
2024 Yeo, K., Li, R., Wu, F., Bouras, G., Mai, L. T. H., Smith, E., . . . Fenix, K. (2024). Identification of consensus head and neck cancer-associated microbiota signatures: a systematic review and meta-analysis of 16S rRNA and The Cancer Microbiome Atlas datasets. Journal of Medical Microbiology, 73(2), 001799-1-001799-18.
DOI Scopus8 WoS6 Europe PMC7
2023 GBD 2019 IMID Collaborators., Olagunju, A., & Gill, T. (2023). Global, regional, and national incidence of six major immune-mediated inflammatory diseases: findings from the global burden of disease study 2019.. EClinicalMedicine, 64(102193), 102193.
DOI Scopus114 WoS100 Europe PMC84
2022 Mercieca-Bebber, R., Barnes, E. H., Wilson, K., Samoon, Z., Walpole, E., Mai, T., . . . Barbour, A. P. (2022). Patient-reported outcome (PRO) results from the AGITG DOCTOR trial: a randomised phase 2 trial of tailored neoadjuvant therapy for resectable oesophageal adenocarcinoma. BMC CANCER, 22(1), 11 pages.
DOI WoS2
2020 Barbour, A. P., Walpole, E. T., Mai, G. T., Barnes, E. H., Watson, D., Ackland, S. P., . . . Smithers, B. M. (2020). Preoperative cisplatin, fluorouracil, and docetaxel with or without radiotherapy after poor early response to cisplatin and fluorouracil for resectable oesophageal adenocarcinoma (AGITG DOCTOR): results from a multicentre, randomised controlled phase II trial. ANNALS OF ONCOLOGY, 31(2), 236-245.
DOI WoS48

Year Citation
2026 Mai, L., Bouras, G., Yeo, K., Barry, E., Kulathunga, B., Hodge, J. -C., . . . Fenix, K. (2026). Genomic Signatures and Functional Pathways Underlying 5-Fluorouracil Resistance in Head and Neck Cancer associated Streptococci.
DOI
2026 Mai, L., Bouras, G., Yeo, K., Hodge, J. -C., Barry, E., Krishnan, S., . . . Fenix, K. (2026). The Genomic Landscape of Head and Neck Cancer-associated Streptococci.
DOI

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