Leah Wright

Leah Wright

School of Chemical Engineering

Faculty of Sciences, Engineering and Technology

Eligible to supervise Masters and PhD (as Co-Supervisor) - email supervisor to discuss availability.

  • Journals
    Year Citation
    2025 Wright, L., Francis, J. A., Curtis, R., & Falconer, R. J. (2025). Dynamic Light Scattering Analysis of Lipid Nanoparticles: Effect of Salts on the Diffusion Interaction Parameter and Hydrodynamic Radius at Infinite Dilution. Analytical Chemistry, 97(4), 6 pages.
    DOI
    2025 Wright, L., Wignall, A., Subramaniam, S., Schultz, H. B., Joyce, P., & Prestidge, C. A. (2025). Enhanced oral absorption and biodistribution to submandibular salivary glands of D-limonene in Sprague Dawley rats via a liquid-lipid formulation approach. International Journal of Pharmaceutics, 670, 125179.
    DOI
    2025 Francis, J. A., Wright, L., van Wegen, R., Zhao, C. -X., & Falconer, R. J. (2025). Effects of salts, buffers and sucrose on protein-protein attractive and repulsive interactions. . International journal of pharmaceutics, 672, 125321.
    DOI
    2024 Ariaee, A., Wardill, H. R., Wignall, A., Elz, A. S., Wright, L., Prestidge, C., & Joyce, P. (2024). Therapeutic Potential of Inulin-Coated MCT Microcapsules in Modulating the Gut Microbiome for Effective Treatment of Diet-Induced Obesity. Advanced Therapeutics, 13 pages.
    DOI
    2024 Capili, M. J. A., Oerlemans, S. K., Wright, L., & Falconer, R. J. (2024). Complexity associated with caprylate binding to bovine serum albumin: Dimerization, allostery, and variance between the change in free energy and enthalpy of binding. Protein Science, 33(12), 11 pages.
    DOI
    2023 Wright, L., Wignall, A., Jõemetsa, S., Joyce, P., & Prestidge, C. A. (2023). A membrane-free microfluidic approach to mucus permeation for efficient differentiation of mucoadhesive and mucopermeating nanoparticulate systems. Drug Delivery and Translational Research, 13(4), 1088-1101.
    DOI Scopus5 Europe PMC3
    2022 Wright, L., Barnes, T. J., Joyce, P., & Prestidge, C. A. (2022). Optimisation of a High-Throughput Model for Mucus Permeation and Nanoparticle Discrimination Using Biosimilar Mucus. Pharmaceutics, 14(12), 2659.
    DOI Scopus7
    2022 Joyce, P., Wignall, A., Peressin, K., Wright, L., Williams, D. B., & Prestidge, C. A. (2022). Chitosan nanoparticles facilitate improved intestinal permeation and oral pharmacokinetics of the mast cell stabiliser cromoglycate. International Journal of Pharmaceutics, 612, 121382.
    DOI Scopus6 Europe PMC3
    2021 Wright, L., Joyce, P., Barnes, T. J., Lundmark, R., Bergström, C. A. S., Hubert, M., & Prestidge, C. A. (2021). A Comparison of Chitosan, Mesoporous Silica and Poly(lactic-co-glycolic) Acid Nanocarriers for Optimising Intestinal Uptake of Oral Protein Therapeutics. Journal of Pharmaceutical Sciences, 110(1), 217-227.
    DOI Scopus9 Europe PMC4
    2021 Wright, L., Joyce, P., Barnes, T. J., & Prestidge, C. A. (2021). Mimicking the Gastrointestinal Mucus Barrier: Laboratory-Based Approaches to Facilitate an Enhanced Understanding of Mucus Permeation. ACS Biomaterials Science & Engineering, 9(6), 19 pages.
    DOI Scopus12 Europe PMC1
    2020 Wright, L., Barnes, T. J., & Prestidge, C. A. (2020). Oral delivery of protein-based therapeutics: Gastroprotective strategies, physiological barriers and in vitro permeability prediction. International Journal of Pharmaceutics, 585, 119488-1-119488-17.
    DOI Scopus26 Europe PMC7
    2018 Wright, L., Rao, S., Thomas, N., Boulos, R. A., & Prestidge, C. A. (2018). Ramizol<sup>®</sup> encapsulation into extended release PLGA micro- and nanoparticle systems for subcutaneous and intramuscular administration: <i>in vitro</i> and <i>in vivo</i> evaluation. Drug Development and Industrial Pharmacy, 44(9), 1451-1457.
    DOI Scopus16 WoS12 Europe PMC7

  • Book Chapters
    Year Citation
    2022 Chapple, L. -A., Ridley, E., Burrell, A., & Fetterplace, K. (2022). Coronavirus Disease 2019 (COVID-19): A Clinical Guide. In M. Dube, & A. Gholamrezanezhad (Eds.), Coronavirus Disease 2019 (Covid-19) A Clinical Guide (Vol. 45, pp. 4414-4424). Wiley-Blackwell.
    DOI

  • Current Higher Degree by Research Supervision (University of Adelaide)
    Date Role Research Topic Program Degree Type Student Load Student Name
    2024 Co-Supervisor Design of Ready-to-Inject Aqueous Formulations of RNA-Lipid Nanoparticles Doctor of Philosophy Doctorate Full Time Ms Jaslene Anne Francis
    2024 Co-Supervisor Building Stability into RNA Lipid Nanoparticle Therapeutics and Vaccines Doctor of Philosophy Doctorate Full Time Mr Ziyue Li
    2024 Co-Supervisor In-vitro mRNA Transcription in Microfluidic Channels for use in RNA Therapeutics and Vaccines Doctor of Philosophy Doctorate Full Time Mr Chandranil Hridaynath Gharekhan
    2024 Co-Supervisor Disentangling the Complexity of mRNA Lipid Nanoparticle (mRNA-LNP) Assembly in Microfluidic Reactors Doctor of Philosophy Doctorate Full Time Ms Jessica Boutros
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