Higher Degree by Research Candidate
Adelaide Medical School
Faculty of Health and Medical Sciences
Lavender Otieno is a PhD candidate in the Adelaide Medical School under the supervision of Dr Simran Sidhu and Associate Professor John Semmler.
Her research interests include: Understanding the neural mechanisms that govern fatigue; Investigating whether these mechanisms alter with ageing; Understanding the impact of fatigue on motor task performance and investigating possible interventions that can be used to override the negative effects of fatigue with ageing.
Fatigue limits our ability to perform everyday tasks. We understand little about the brain areas involved in the development of fatigue during human locomotor movements, and the impact of centrally driven fatigue on movements that are vital for interaction with our environment. Having a comprehensive understanding of the neural mechanisms and interactions that occur between the components in the brain during exercise is critical to establish the anatomical sites of intervention that will result in the most effective functional outcomes. In many social and economic contexts, including vehicle driving, manual industrial operations and defence, physical fatigue has an important influence on cognitive and motor performance during goal directed movements. Furthermore, exercise intolerance remains quite high in advancing age. To improve human work productivity, both the neurophysiological and psychophysical aspects of fatigue must be addressed.
Title and Description: AGE-RELATED CHANGES IN GABA-MEDIATED INHIBITION WITH FATIGUING SINGLE JOINT EXERCISE
Date Position Institution name 2018 Higher Degree by Research Candidate University of Adelaide
Awards and Achievements
Date Type Title Institution Name Country Amount 2019 Award 2019 Best Poster Presentation Award 2019 ANS Sensorimotor Symposium Australia 100 2018 Scholarship Adelaide Graduate Research Scholarships University of Adelaide Australia — 2017 Achievement Class I honours award University of Adelaide Australia — 2016 Scholarship 2016 Summer Research Scholarship University of Adelaide Australia — 2014 Award 2014-2016 Faculty of Science Outstanding Academic Achievement Award University of Adelaide Australia —
Date Institution name Country Title 2017 - 2017 The University of Adelaide Australia Honours Degree in Bachelor of Health and Medical Sciences 2014 - 2016 The University of Adelaide Australia Bachelor of Science (Biomedical Science)
Year Citation 2020 Opie, G. M., Otieno, L. A., Pourmajidian, M., Semmler, J. G., & Sidhu, S. K. (2020). Older Adults Differentially Modulate Transcranial Magnetic Stimulation-Electroencephalography Measures of Cortical Inhibition during Maximal Single-joint Exercise.. Neuroscience, 425, 181-193.
2019 Otieno, L. A., Opie, G., Semmler, J., Ridding, M., & Sidhu, S. (2019). Intermittent single-joint fatiguing exercise reduces TMS-EEG measures of cortical inhibition. Journal of neurophysiology, 121(2), 471-479.
DOI Scopus2 WoS2 Europe PMC1
Assist with course demonstration during practical classes.
Current course teaching (assistance)
- Human Motor Behaviour and Learning (HLTH SC 3201; Semester 2)
- Research Placement Part 1 (HLTH SC 3009A; Semester 1 & 2)
- Research Placement Part 2 (HLTH SC 3009B; Semester 1 & 2)
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