Kristen Bremmell

Dr Kristen Bremmell

Senior Lecturer, Pharmaceutical Science

School of Pharmacy and Biomedical Science

College of Health

Eligible to supervise Masters and PhD - email supervisor to discuss availability.


Year Citation
2025 Hosseini Kharat, M., Bremmell, K. E., & Prestidge, C. A. (2025). Why do lipid nanoparticles target the liver? Understanding of biodistribution and liver-specific tropism. Molecular Therapy Methods and Clinical Development, 33(1, article no. 101436), 1-14.
DOI
2025 Hosseini-Kharat, M., Bremmell, K. E., Grubor-Bauk, B., & Prestidge, C. A. (2025). Enhancing non-viral DNA delivery systems: Recent advances in improving efficiency and target specificity. Journal of Controlled Release, 378, 170-194.
DOI Scopus14 WoS13 Europe PMC9
2025 Hosseini-Kharat, M., Wignall, A., Mekonnen, Z. A., Ung, B. S. -Y., Chereda, B., Bremmell, K. E., . . . Prestidge, C. A. (2025). Microfluidic Optimization of PEI-Lipid Hybrid Nanoparticles for Efficient DNA Delivery and Transgene Expression. Pharmaceutics, 17(4), 454.
DOI Scopus1 WoS1
2025 Taheri, A., Almasri, R., Wignall, A., Feltrin, F., Bremmell, K. E., Joyce, P., & Prestidge, C. A. (2025). Enteric coating enhances the Biopharmaceutical performance of a silica-lipid formulation of Abiraterone Acetate. Pharmaceutics, 17(10, article no. 1289), 1-12.
DOI
2024 Taheri, A., Almasri, R., Wignall, A., Schultz, H. B., Elz, A. S., Ariaee, A., . . . Prestidge, C. A. (2024). Enhancing the pharmacokinetics of abiraterone acetate through lipid-based formulations: addressing solubility and food effect challenges. Drug Delivery and Translational Research, online(11), 3770-3782.
DOI WoS2 Europe PMC1
2024 Nguyen, T. M., Joyce, P., Ross, D. M., Bremmell, K., Jambhrunkar, M., Wong, S. S., & Prestidge, C. A. (2024). Combating Acute Myeloid Leukemia via Sphingosine Kinase 1 Inhibitor-Nanomedicine Combination Therapy with Cytarabine or Venetoclax. Pharmaceutics, 16(2), 209-1-209-16.
DOI Scopus7 WoS5 Europe PMC3
2023 Bremmell, K. E., Barnes, T. J., Hughes, B. P., Birbeck, D. J., Johnson, J., & Suppiah, V. (2023). Design and implementation of a program wide pharmaceutical compounding curriculum using the scaffold learning approach. CURRENTS IN PHARMACY TEACHING AND LEARNING, 15(2), 178-185.
DOI Scopus1 WoS1
2023 Jambhrunkar, M., Maghrebi, S., Doddakyathanahalli, D., Wignall, A., Prestidge, C. A., & Bremmell, K. E. (2023). Mesoporous organosilica nanoparticles to fight intracellular staphylococcal aureus infections in macrophages. Pharmaceutics, 15(4, article no. 1037), 1-12.
DOI WoS4 Europe PMC1
2023 Nguyen, T. M., Jambhrunkar, M., Wong, S. S., Ross, D. M., Joyce, P., Finnie, J. W., . . . Prestidge, C. A. (2023). Targeting Acute Myeloid Leukemia Using Sphingosine Kinase 1 Inhibitor-Loaded Liposomes.. Molecular pharmaceutics, 20(8), 3937-3946.
DOI Scopus8 WoS7 Europe PMC6
2023 Hassan, M. M., Romana, B., Mao, G., Kumar, N., Sonvico, F., Thordarson, P., . . . Prestidge, C. A. (2023). Liposome-Micelle-Hybrid (LMH) carriers for controlled co-delivery of 5-FU and paclitaxel as chemotherapeutics. Pharmaceutics, 15(7, article no. 1886), 1-17.
DOI
2023 Taheri, A., Bremmell, K. E., Joyce, P., & Prestidge, C. A. (2023). Battle of the milky way: lymphatic targeted drug delivery for pathogen eradication. Journal of Controlled Release, 363, 507-524.
DOI
2022 Almasri, R., Schultz, H. B., Møller, A., Bremmell, K. E., Garcia Bennett, A., Joyce, P., & Prestidge, C. A. (2022). Role of silica intrawall microporosity on abiraterone acetate solubilization and in vivo oral absorption. Molecular Pharmaceutics, 19(4), 1091-1103.
DOI
2022 Chang, P. K. C., Prestidge, C. A., & Bremmell, K. E. (2022). PAMAM versus PEI complexation for siRNA delivery: interaction with model lipid membranes and cellular uptake. Pharmaceutical Research, 39(6), 1151-1163.
DOI
2022 Meola, T. R., Bremmell, K. E., Williams, D. B., Schultz, H. B., & Prestidge, C. A. (2022). Bio-enabling strategies to mitigate the pharmaceutical food effect: A mini review. International Journal of Pharmaceutics, 619(121695), 14 pages.
DOI Scopus7 WoS6 Europe PMC4
2022 Wang, W., Joyce, P., Bremmell, K., Milne, R., & Prestidge, C. A. (2022). Liposomal 5-fluorouracil polymer complexes facilitate tumor-specific delivery: pharmaco-distribution kinetics using microdialysis. Pharmaceutics, 14(2, article no. 221), 1-16.
DOI Scopus10 WoS8 Europe PMC6
2021 Meola, T. R., Joyce, P., Wignall, A., Bremmell, K. E., & Prestidge, C. A. (2021). Harnessing the potential of nanostructured formulations to mimic the food effect of lurasidone. International Journal of Pharmaceutics, 608(121098), 10 pages.
DOI Scopus11 WoS11 Europe PMC7
2020 Almasri, R., Joyce, P., Schultz, H. B., Thomas, N., Bremmell, K. E., & Prestidge, C. A. (2020). Porous nanostructure, lipid composition, and degree of drug supersaturation modulate in vitro fenofibrate solubilization in silica-lipid hybrids. Pharmaceutics, 12(7, article no. 687), 1-22.
DOI
2020 Romana, B., Hassan, M. M., Sonvico, F., Garrastazu Pereira, G., Mason, A. F., Thordarson, P., . . . Prestidge, C. A. (2020). A liposome-micelle-hybrid (LMH) oral delivery system for poorly water-soluble drugs: enhancing solubilisation and intestinal transport. European Journal of Pharmaceutics and Biopharmaceutics, 154, 338-347.
DOI
2020 Bremmell, K. E., Briskey, D., Meola, T. R., Mallard, A., Prestidge, C. A., & Rao, A. (2020). A self-emulsifying Omega-3 ethyl ester formulation (AquaCelle) significantly improves eicosapentaenoic and docosahexaenoic acid bioavailability in healthy adults. European Journal of Nutrition, 59(6), 2729-2737.
DOI Scopus24 WoS22 Europe PMC15
2019 Bremmell, K. E., & Prestidge, C. A. (2019). Enhancing oral bioavailability of poorly soluble drugs with mesoporous silica based systems: opportunities and challenges. Drug development and industrial pharmacy, 45(3), 349-358.
DOI
2017 Yasmin, R., Rao, S., Bremmell, K. E., & Prestidge, C. (2017). Synergistic role of solid lipid and porous silica in improving the oral delivery of weakly basic poorly water soluble drugs. European journal of pharmaceutical sciences, 96, 508-514.
DOI Scopus21 WoS19 Europe PMC10
2017 Chang, P. K. C., Prestidge, C. A., & Bremmell, K. E. (2017). Interfacial analysis of siRNA complexes with poly-ethylenimine (PEI) or PAMAM dendrimers in gene delivery. Colloids and surfaces B: biointerfaces, 158, 370-378.
DOI
2017 Singh, G., Bremmell, K., Griesser, H. J., & Kingshott, P. (2017). Colloid-probe AFM studies of the surface functionality and adsorbed proteins on binary colloidal crystal layers. RSC advances, 7(12), 7329-7337.
DOI Scopus3 WoS3
2016 Chang, P. K., Prestidge, C. A., Barnes, T. J., & Bremmell, K. E. (2016). Impact of PEGylation and non-ionic surfactants on the physical stability of the therapeutic protein filgrastim (G-CSF). RSC advances, 6(82), 78970-78978.
DOI
2016 Yasmin, R., Rao, S., Bremmell, K. E., & Prestidge, C. A. (2016). Porous Silica-Supported Solid Lipid Particles for Enhanced Solubilization of Poorly Soluble Drugs. AAPS Journal, 18(4), 876-885.
DOI Scopus8 WoS8 Europe PMC5
2015 Diéguez, L. M., Winter, M. A., Pocock, K. J., Bremmell, K. E., & Thierry, B. (2015). Efficient microfluidic negative enrichment of circulating tumor cells in blood using roughened PDMS. Analyst, 140(10), 3365-3372.
DOI Scopus48 WoS46 Europe PMC28
2015 Ho, T. T. M., Bremmell, K. E., Krasowska, M., MacWilliams, S. V., Richard, C. J. E., Stringer, D. N., & Beattie, D. A. (2015). In Situ ATR FTIR Spectroscopic Study of the Formation and Hydration of a Fucoidan/Chitosan Polyelectrolyte Multilayer. Langmuir, 31(41), 11249-11259.
DOI Scopus42 WoS40 Europe PMC20
2015 Ho, T. T. M., Bremmell, K. E., Krasowska, M., Stringer, D. N., Thierry, B., & Beattie, D. A. (2015). Tuning polyelectrolyte multilayer structure by exploiting natural variation in fucoidan chemistry. Soft Matter, 11(11), 2110-2124.
DOI Scopus38 WoS35 Europe PMC18
2015 Singh, G., Bremmell, K. E., Griesser, H. J., & Kingshott, P. (2015). Colloid-probe AFM studies of the interaction forces of proteins adsorbed on colloidal crystals. Soft matter, 11(16), 3188-3197.
DOI Scopus9 WoS8 Europe PMC2
2014 Yasmin, R., Tan, A., Bremmell, K. E., & Prestidge, C. A. (2014). Lyophilized silica-lipid hybrid carriers for poorly water-soluble drugs : physicochemical and in vitro pharmaceutical investigations. Journal of pharmaceutical sciences, 103(9), 2950-2959.
DOI Europe PMC15
2014 Shin, Y., Cheung, W. H., Ho, T. T. M., Bremmell, K. E., & Beattie, D. A. (2014). Insights into hydrophobic molecule release from polyelectrolyte multilayer films using In situ and ex situ techniques. Physical chemistry chemical physics, 16(40), 22409-22417.
DOI
2013 Bremmell, K. E., Tan, A., Martin, A., & Prestidge, C. A. (2013). Tableting lipid-based formulations for oral drug delivery: a case study with silica nanoparticle-lipid-mannitol hybrid microparticles. Journal of pharmaceutical sciences, 102(2), 684-693.
DOI Europe PMC18
2013 Bremmell, K. E., Britcher, L., & Griesser, H. J. (2013). Steric and electrostatic surface forces on sulfonated PEG graft surfaces with selective albumin adsorption. Colloids and surfaces B : biointerfaces, 106(1), 102-108.
DOI
2013 Kempson, I. M., Chang, P., Bremmell, K., & Prestidge, C. A. (2013). Low temperature thermal dependent filgrastim adsorption behavior detected with ToF-SIMS. Langmuir, 29(50), 15573-15578.
DOI Scopus9 WoS10 Europe PMC6
2011 Singh, G., Griesser, H. J., Bremmell, K., & Kingshott, P. (2011). Highly ordered nanometer-scale chemical and protein patterns by binary colloidal crystal lithography combined with plasma polymerization. Advanced functional materials, 21(3), 540-546.
DOI Scopus66 WoS64
2010 Banerjee, K. K., Kumar, S., Bremmell, K. E., & Griesser, H. J. (2010). Molecular-level removal of proteinaceous contamination from model surfaces and biomedical device materials by air plasma treatment. Journal of hospital infection, 76(3), 234-242.
DOI Scopus14 WoS13 Europe PMC4
2010 Regini, J., Ecroyd, H., Meehan, S., Bremmell, K., Clarke, M., Lammie, D., . . . Carver, J. (2010). The interaction of unfolding α-lactalbumin and malate dehydrogenase with the molecular chaperone αB-crystallin: a light and X-ray scattering investigation. Molecular Vision, 16(260-62), 2446-2456.
Scopus27 WoS28 Europe PMC22
2008 McGuire, M. J., Addai Mensah, J., & Bremmell, K. E. (2008). Improved dewaterability of iron oxide dispersions : rhe role of polymeric flocculant Type, pH and shear. Asia-Pacific Journal of Chemical Engineering, 3(1), 18-23.
DOI Scopus10 WoS8
2008 McFarlane, A. J., Yeap, K. Y., Bremmell, K. E., & Addai Mensah, J. (2008). The influence of flocculant adsorption kinetics on the dewaterability of kaolinite and smectite clay minerals dispersions. Colloids and surfaces A : physicochemical and engineering aspects, 317(1-3), 39-48.
DOI Scopus37 WoS31
2006 McGuire, M. J., Addai Mensah, J., & Bremmell, K. E. (2006). The effect of polymer structure type, pH and shear on the interfacial chemistry, rheology and dewaterability of model iron oxide dispersions. Colloids and surfaces A : physicochemical and engineering aspects, 275(1-3), 153-160.
DOI Scopus45 WoS42
2006 McFarlane, A. J., Bremmell, K. E., & Addai Mensah, J. (2006). Improved dewatering behavior of clay minerals dispersions via interfacial chemistry and particle interactions optimization. Journal of colloid and interface science, 293(1), 116-127.
DOI Scopus81 WoS70 Europe PMC9
2006 McGuire, M. J., Addai Mensah, J., & Bremmell, K. E. (2006). Spectroscopic investigation of the adsorption mechanisms of polyacrylamide polymers onto iron oxide particles. Journal of colloid and interface science, 299(2), 547-555.
DOI Scopus39 WoS38 Europe PMC7
2006 Bremmell, K. E., Evans, A. M., & Prestidge, C. A. (2006). Deformation and nano-rheology of red blood cells. Colloids and surfaces B : biointerfaces, 50(1), 43-48.
DOI Scopus78 WoS69 Europe PMC42
2006 Kaggwa, G. B. N., Huynh, L. V., Ralston, J., & Bremmell, K. E. (2006). The influence of polymer structure and morphology on talc wettability. Langmuir, 22(7), 3221-3227.
DOI
2006 Bremmell, K. E., Kingshott, P., Ademovic, Z., Winther Jensen, B., & Griesser, H. J. (2006). Colloid probe AFM investigation of interactions between fibrinogen and PEG-like plasma polymer surfaces. Langmuir: the A C S journal of surfaces and colloids, 22(1), 313-318.
DOI
2005 Kaggwa, G. B. N., Froebe, S., Huynh, L. V., Ralston, J., & Bremmell, K. E. (2005). Morphology of adsorbed polymers and solid surface wettability. Langmuir, 21(10), 4695-4704.
DOI
2005 Zhang, H., Bremmell, K. E., & Smart, R. S. C. (2005). Direct measurement of interactions between adsorbed vitronectin layers. Journal of biomedical materials research part A, 74A(1), 59-68.
DOI
2005 Al Bataineh, S. A., Hamilton Brown, P., Meagher, L., Bremmell, K. E., Jasieniak, M., & Griesser, H. J. (2005). Relationships between surface properties and protein adsorption. European cells and materials journal, 10(5), 21.
2005 Bremmell, K. E., Fornasiero, D., & Ralston, J. (2005). Pentlandite-lizardite interactions and implications for their separation by flotation. Colloids and surfaces A : physicochemical and engineering aspects, 252(2-3), 207-212.
DOI
2005 McFarlane, A. J., Addai Mensah, J., & Bremmell, K. E. (2005). Rheology of flocculated kaolinite dispersions. Korea-Australia Rheology Journal, 17(4), 181-190.
Scopus24 WoS21
2005 McFarlane, A. J., Addai Mensah, J., & Bremmell, K. E. (2005). Microstructure, rheology and dewatering behaviour of smectite dispersions during orthokinetic flocculation. Minerals Engineering, 18(12), 1173-1182.
DOI Scopus50 WoS46
2005 McFarlane, A. J., Bremmell, K. E., & Addai Mensah, J. (2005). Optimising the dewatering behaviour of clay tailings through interfacial chemistry, orthokinetic flocculation and controlled shear. Powder Technology, 160(1), 27-34.
DOI Scopus69 WoS62
2005 Bremmell, K. E., & Addai Mensah, J. (2005). Interfacial-chemistry mediated behavior of colloidal talc dispersions. Journal of colloid and interface science, 283(2), 385-391.
DOI Scopus59 WoS54 Europe PMC9
2003 Zhang, H., Bremmell, K. E., Kumar, S., & Smart, R. S. C. (2003). Vitronectin adsorption on surfaces visualized by tapping mode atomic force microscopy. Journal of biomedical materials research part A, 68A(3), 479-488.
DOI

Year Citation
2009 Bremmell, K. E., Song, Y., Simovic, S., & Prestidge, C. A. (2009). Tabletisation of novel solid dosage forms based on nanoparticle-lipid microcapsules for oral delivery. In PharmSciFair Conference. France: PharmSciFair.
2006 McFarlane, A. J., Addai Mensah, J., & Bremmell, K. E. (2006). Optimizing flocculation and dewatering of clay dispersions via flocculant chemistry, temperature and pulp shear. In Proceedings of the XXIII International Mineral Processing Congress. Istanbul, Turkey: Promed Advertising Ltd.
2006 Britcher, L. G., Bremmell, K. E., & Griesser, H. J. (2006). Understanding the non-fouling behaviour of poly(ethylene oxide) surfaces. In Proceedings of the Chemeca 2006. New Zeland: Centre for Continuing Education.
2006 Beattie, D. A., Bremmell, K. E., Cuba Chiem, L. T., Huynh, L. V., Kaggwa, G. B. N., & Ralston, J. (2006). Correlation of Absorbed Polymer Layer Properties with Depressant Performance. In Fundamentals of Mineral Processing: Interfacial Phenomena in Fine Particle Technology, 6th UBC-McGill-U of A Biennial Symposium on Interfacial Phenomena in Fine Particle Technology, Montreal, Canada, 1-4 October 2006. NA: Canadian Institute of Mining, Metallurgy and Petroleum.
2006 McGuire, M. J., Bremmell, K. E., & Addai Mensah, J. (2006). Improved dewaterability of iron oxide dispersions : the role of polymeric flocculant type, pH and shear. In Chemeca 2006 : knowledge and innovation : conference proceedings. Auckland, N.Z.: Centre for Continuing Education.
2006 Bal, H. M., Bremmell, K. E., & Addai Mensah, J. (2006). Single and dual polymer flocculation and dewatering behaviour of gibbsite dispersions. In Chemeca 2006 : knowledge and innovation : conference proceedings. Auckland, N.Z.: Centre for Continuing Education.
2006 McGuire, M. J., Addai Mensah, J., & Bremmell, K. E. (2006). The Impact of Polymeric Flocculant Structure and Absorption Behaviour on the Interfacial Chemistry and Rheology of Colloidal Iron Oxide Dispersions. In Chemeca 2006 : knowledge and innovation : conference proceedings. Auckland, N.Z.: Centre for Continuing Education.
2005 Ametov, I., Bremmell, K. E., & Prestidge, C. A. (2005). Correlation of bulk rheology of human blood with nano-rheology and deformability of individual erythrocytes. In Smart Solutions Doing More with Less, Chemeca 2005: Conference Proceedings. Australia: Institution of Engineers, IChemE, SCENZ and RACI, with University of Queensland.
2004 McFarlane, A. J., Bremmell, K. E., & Addai Mensah, J. (2004). Microstructure and rheology of smectite dispersions during flocculation and dewatering. In Thirteenth annual JKMRC(Julius Kruttschnitt Mineral Research Centre) postgraduate conference. UK: Julius Kruttschnitt Mineral Research Centre.
2004 McFarlane, A. J., Addai Mensah, J., & Bremmell, K. E. (2004). Optimising the dewatering behaviour of clay tailings via interfacial chemistry and shear induced particle interactions. In Chemeca 2004 : proceedings. NSW, Australia: University of New South Wales.
2003 Addai Mensah, J., Huynh, L. V., Bremmell, K. E., & Ralston, J. (2003). Surface chemistry and stability of colloidal iron oxide and titanium dioxide dispersions. In CHEMECA 2003 Products and processes for the 21st century. Australia.
  • Biopolymer films for enhanced wound management, Wound Management Innovation CRC, 16/02/2015 - 31/03/2018

Courses I teach

  • BIOL 4014 Honours Biomedical Research B (2025)
  • BIOL 4015 Honours Biomedical Research A (2025)
  • PHAR 2016 Dosage Form Design 2 (2025)
  • BIOL 4014 Honours Biomedical Research B (2024)
  • BIOL 4015 Honours Biomedical Research A (2024)
  • PHAR 2016 Dosage Form Design 2 (2024)

Programs I'm associated with

  • IBPA - Bachelor of Pharmaceutical Science
  • IHPC - Bachelor of Pharmacy (Honours)
  • IHBY - Bachelor of Biomedical Research (Honours)

Date Role Research Topic Program Degree Type Student Load Student Name
2024 Co-Supervisor - - Master Full Time Mr Alex Hunter
2024 Co-Supervisor - Doctor of Philosophy Doctorate Full Time Mr Ali Taheri
2023 Principal Supervisor - Doctor of Philosophy Doctorate Full Time Miss Yukta Hegishte
2023 Co-Supervisor - Doctor of Philosophy Doctorate Full Time Miss Thi My Hanh Tran
2022 Principal Supervisor - Doctor of Philosophy Doctorate Full Time Miss Nikita Parekh
2021 Co-Supervisor - Doctor of Philosophy Doctorate Full Time Mrs Ruba Jawad Abdulrahman Almasri
2021 Co-Supervisor - Doctor of Philosophy Doctorate Full Time Ms Mitra Hosseini Kharat

Date Role Research Topic Program Degree Type Student Load Student Name
2008 - 2010 Co-Supervisor The Synthesis of Polyol from Rice Bran Oil (RBO) through Epoxidation and Hydroxylation Reactions Master of Engineering Science Master Full Time Mr Edy Purwanto
2007 - 2011 Co-Supervisor Development of Multifunctional Nanomaterials and Adsorption - Photocatalysis Hybrid System for Wastewater Reclamation Doctor of Philosophy Doctorate Full Time Miss Vipasiri Vimonses

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