Dr Kevin Fenix
School of Medicine
College of Health
Eligible to supervise Masters and PhD - email supervisor to discuss availability.
Dr Kevin Fenix, PhD is a Chief Medical Scientist with the Department of Medical Oncology, The Queen Elizabeth Hospital located at the Basil Hetzel Institute for Translational Health Research. He is also a Cancer Council Research Fellow and Affiliate Senior Lecturer with the Solid Tumour Research Group, School of Medicine, College of Health.
His current research utilises both patient samples and clinically relevant in vitro and in vivo models to find new treatment modalities for infections and cancer. Dr Fenix has successfully supervised Honours, Master and PhD students to completion and is a recipient of multiple competitive research grants to support his research.
I am a Chief Medical Scientist at the Department of Medical Oncology, The Queen Elizabeth Hospital. My research interests include Cancer Immunotherapy, Cancer Biology, Immunobiology and Host/Microbe Interactions. Additionally, I collaborate closely with the Upper GI and ENT Surgery Departments at the Basil Hetzel Institute for Translational Health Research. Currently, I am identifying treatment modalities for Colorectal Cancer and Head and Neck Cancer.
Projects related to this work are available for HDR, Honours and Third Year Students. Potential students can apply for competitive scholarships for Honours, Masters and PhD (Top-Up) offered by the Basil Hetzel Institute.
Current projects include:
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Identifying distinct tumour-infiltrating immune cells with prognostic capacity for cancer metastasis and patient survival.
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Developing T cell-based therapies for cancer.
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Understanding and exploiting the tumour microbiome to develop new cancer treatments.
| Date | Position | Institution name |
|---|---|---|
| 2026 - ongoing | Affiliate Senior Lecturer | Adelaide University |
| 2026 - ongoing | Chief Medical Scientist | Queen Elizabeth Hospital |
| 2018 - 2026 | Postdoctoral Research Fellow | The University of Adelaide |
| Date | Type | Title | Institution Name | Country | Amount |
|---|---|---|---|---|---|
| 2024 | Fellowship | Cancer Council SA Mid-Career Research Fellowship | Cancer Council SA | Australia | - |
| 2018 | Fellowship | The Hospital Research Foundation Early Career Fellowship | The Hospital Research Foundation | Australia | - |
| 2017 | Award | Dean’s Commendation for Thesis Excellence | The University of Adelaide | Australia | - |
| 2012 | Scholarship | Australian Postgraduate Award | The University of Adelaide | Australia | - |
| 2010 | Research Award | Derrick Rowley Prize for Honours in Microbiology and Immunology | The University of Adelaide | Australia | - |
| Language | Competency |
|---|---|
| English | Can read, write, speak, understand spoken and peer review |
| Filipino; Pilipino | Can read, write, speak and understand spoken |
| Date | Institution name | Country | Title |
|---|---|---|---|
| 2017 | University of Adelaide | Australia | PhD |
| 2010 | University of Adelaide, Adelaide | Australia | Bsc (Hons) |
| 2009 | University of Adelaide, Adelaide | Australia | Bsc (Biomedical Science) |
| Year | Citation |
|---|---|
| 2017 | Gregor, C. E., Kara, E. E., Fenix, K. A., McKenzie, D. R., Comerford, I., & McColl, S. R. (2017). Effector T helper cell recruitment to inflammatory sites via CCR2. In SWISS MEDICAL WEEKLY Vol. 147 (pp. 64S). E M H SWISS MEDICAL PUBLISHERS LTD. |
| Year | Citation |
|---|---|
| 2016 | McKenzie, D., Kara, E., Tyllis, T., Bastow, C., Fenix, K., Gregor, C., . . . McColl, S. (2016). Dynamic expression of CCR6 and CCR2 balances homeostatic and inflammatory trafficking of γδT17 cells. Poster session presented at the meeting of EUROPEAN JOURNAL OF IMMUNOLOGY. Melbourne, AUSTRALIA: WILEY-BLACKWELL. |
| 2016 | Kara, E., Bastow, C., Mckenzie, D., Gregor, C., Fenix, K., Norton, T., . . . Mccoll, S. (2016). The atypical chemokine receptor ACKR4 shapes early antibody responses. Poster session presented at the meeting of EUROPEAN JOURNAL OF IMMUNOLOGY. Melbourne, AUSTRALIA: WILEY-BLACKWELL. |
| Year | Citation |
|---|---|
| 2026 | Mai, L., Mai, L., Bouras, G., Yeo, K., Barry, E., Kulathunga, B., . . . Fenix, K. (2026). Genomic Signatures and Functional Pathways Underlying 5-Fluorouracil Resistance in Head and Neck Cancer associated Streptococci. DOI |
| 2026 | King, C., Iqbal, M., Shokati, E., Ying Li, C. M., Li, R., Tomita, Y., . . . Fenix, K. (2026). Comparative benchmarking of single-cell transcriptomes and immune repertoires across technologies. DOI |
| 2024 | Li, C. M. Y., Briggs, M., Lee, Y. -R., Tin, T., Young, C., Pierides, J., . . . Fenix, K. (2024). Use of tryptic peptide MALDI mass spectrometry imaging to identify the spatial proteomic landscape of colorectal cancer liver metastases. DOI |
| 2024 | Li, R., Liu, S., Yeo, K., Edwards, S., Li, M. Y., Santos, R., . . . Smith, E. (2024). Circulating SFRP5 levels are elevated in colorectal cancer and correlate with overall survival in stage II-III disease. DOI |
| 2024 | Yeo, K., Connell, J., Bouras, G., Smith, E., Murphy, W., Hodge, J. -C., . . . Fenix, K. A. (2024). A comparison between full-length 16S rRNA Oxford Nanopore sequencing and Illumina V3-V4 16S rRNA sequencing in head and neck cancer tissues. DOI Europe PMC1 |
| 2024 | Yeo, K., Wu, F., Li, R., Smith, E., Wormald, P. -J., Valentine, R., . . . Fenix, K. (2024). Is Short-Read 16S rRNA Sequencing of Oral Microbiome Sampling a Suitable Diagnostic Tool for Head and Neck Cancer?. DOI |
| 2024 | Burdon, I., Bouras, G., Fenix, K., Yeo, K., Connell, J., Cooksley, C., . . . Psaltis, A. J. (2024). Metagenomics or Metataxonomics: Best Practice Methods to Uncover the Sinus Microbiome. DOI |
| 2023 | Yeo, K., Li, R., Wu, F., Bouras, G., Mai, L. T. H., Smith, E., . . . Fenix, K. (2023). Identification of consensus head and neck cancer-associated microbiota signatures: a meta-analysis of 16S rRNA and The Cancer Microbiome Atlas datasets. DOI |
| 2023 | Ying Li, C. M., Tomita, Y., Dhakal, B., Tin, T., Li, R., Wright, J. A., . . . Fenix, K. (2023). Generation and assessment of cytokine-induced killer cells for the treatment of colorectal cancer liver metastases. DOI |
Dr Kevin Fenix is a recipient of multiple competitive research funding awards (>$3million) from MRFF, Cancer Council SA, Tour de Cure, Cure Cancer Australia, the Ray and Shirl Norman Trust, and The Hospital Research Foundation Group.
A selection of competitive funding awards are listed below:
| Year | Title | Role | Amount |
|---|---|---|---|
| 2026 | A Pilot Study for the IMPACT-CRC Trial: IMPlementAtion of Cytokine-Induced Killer Cell Therapy for Metastatic ColoRectal Cancer (MRFF:2045015) | CIB | $758,120 |
| 2024 | Microbial infiltrates in head and neck cancers as mediators of chemotherapy responsiveness. (HSCGB Ray and Shirl Norman Cancer Research Trust) | CIB | $358,901 |
| 2024 | Cytokine induced killer cell therapy as a treatment for metastatic colorectal cancer (Cancer Council SA Research Fellowship) | CIA | $480,000 |
| 2024 | The development of more effective next-generation cytokine-induced killer cell therapies for the improved treatment of metastatic colorectal cancer (Cure Cancer) | CIA | $200,000 |
| 2020 | Pre-clinical assessment of a patient-derived cellular immunotherapy for metastatic colorectal cancer. (Tour de Cure) | CIA | $50,000 |
| 2019 | Construction of the South Australian Liver Tissue-Biobank (SALT) for discovery and development of prognostic biomarkers of colorectal cancer liver metastasis. (Beat Cancer SA and The Hospital Research Foundation) | CIB | $200,000 |
| 2018 | Study of bioactivity of Hengshan Astragalus Shiitake as biological response modifiers in cancer therapy ( Flinders University Innovation Patnership Seed Grant and Shanxi Yulongxiang agricultural development Co., Ltd) | CID | $100,000 |
| 2018 | Using Tissue-Resident T cells to develop new prognostics and treatments against bowel cancer. ( The Hospital Research Foundation Early Career Fellowship) | CIA | $240,000 |
| Year | Source | Conference | Amount |
|---|---|---|---|
| 2025 | The Hospital Research Foundation Group (BHI International Travel Award) | International Congress of Immunology 2025 (Vienna, Austria) | $2,500 |
| 2024 | Adelaide Medical School and The Hospital Research Foundation Group (BHI International Travel Award) | European Association for Cancer Research Annual Scientific Conference (Rotterdam, Netherlands) and Laboratory Visits (Italy and Germany) | $6,500 |
| 2022 | The Hospital Research Foundation Group (BHI National Travel Award) | Annual Scientific Meeting of Australasian Society for Immunology (Melbourne, Australia) | $500 |
| 2019 | Faculty of Health and Medical Sciences | Lorne Cancer Conference (2019) | $1000 |
| 2017 | Australasian Society for Immunology | 46th Annual Scientific Meeting of Australasian Society for Immunology (Brisbane, Australia) | $1400 |
| 2016 | International Congress of Immunology | International Congress of Immunology 2016 (Melbourne, Australia) | $1000 |
| 2014 | School of Molecular and Biomedical Science and Australasian Society for Immunology | Annual Scientific Meeting of Australasian Society for Immunology (Wollongong, Australia) | $1500 |
| Date | Role | Research Topic | Program | Degree Type | Student Load | Student Name |
|---|---|---|---|---|---|---|
| 2026 | Principal Supervisor | Investigating the Role of the Oral Microbiome in Treatment Response and Immune Modulation in Head and Neck Cancer | Doctor of Philosophy | Doctorate | Full Time | Ms Yue Feng |
| 2026 | Principal Supervisor | Identify and Optimize Synergistic Combination Partners to Enhance CIK Infiltration and anti-Tumour Efficacy in Colorectal Cancers | Doctor of Philosophy | Doctorate | Full Time | Ms Bixi Kang |
| 2026 | Principal Supervisor | Understanding the anti-cancer mechanisms of Cytokine-Induced Killer Cells in 3D Patient-Derived Colorectal Cancer Organoids | Doctor of Philosophy | Doctorate | Full Time | Mr Marzuq Mohammad Alam |
| 2026 | Principal Supervisor | Understanding the anti-cancer mechanisms of Cytokine-Induced Killer Cells in 3D Patient-Derived Colorectal Cancer Organoids | Doctor of Philosophy | Doctorate | Full Time | Mr Marzuq Mohammad Alam |
| 2025 | Co-Supervisor | Intra-tumoural and oral microbiome composition and oral cancer outcomes | Master of Philosophy (Surgery) | Master | Full Time | Mr Jonathan Daniel |
| 2025 | Co-Supervisor | Intra-tumoural and oral microbiome composition and oral cancer outcomes | Doctor of Philosophy | Doctorate | Full Time | Mr Jonathan Daniel |
| 2024 | Principal Supervisor | The development of more effective next-generation cytokine-induced killer cell therapies for the improved treatment of metastatic colorectal cancer | Doctor of Philosophy | Doctorate | Full Time | Mrs Elham Shokati |
| 2023 | Co-Supervisor | Repurposing the anti-anginal drug perhexiline for the treatment of cancer | Doctor of Philosophy | Doctorate | Full Time | Ms Fangmeinuo Wu |
| 2023 | Principal Supervisor | Target the tumour microbiome to improve head & neck cancer treatment outcomes | Doctor of Philosophy | Doctorate | Full Time | Ms Linh Mai |
| 2022 | Co-Supervisor | The role of various Staphylococcus species in eliciting inflammation in Chronic rhinosinusitis | Doctor of Philosophy | Doctorate | Full Time | Mr Sintayehu Ambachew Wondemagegn |
| 2022 | Co-Supervisor | Over-expression of SFRP5 in hepatocytes: a novel treatment strategy for colorectal cancer liver metastases | Doctor of Philosophy | Doctorate | Full Time | Mr Runhao Li |
| Date | Role | Research Topic | Program | Degree Type | Student Load | Student Name |
|---|---|---|---|---|---|---|
| 2021 - 2024 | Co-Supervisor | Characterising the Microbiome and its Diagnostic and Prognostic Value in Head and Neck Cancer | Doctor of Philosophy | Doctorate | Full Time | Mr Kenny Ker Li Yeo |
| 2021 - 2022 | Co-Supervisor | Perhexiline as a Potential Treatment for Colorectal Cancer | Doctor of Philosophy | Doctorate | Full Time | Mrs Bimala Dhakal |
| 2020 - 2024 | Co-Supervisor | INVESTIGATION OF CYTOKINE-INDUCED KILLER CELL THERAPY FOR THE TREATMENT OF COLORECTAL CANCER LIVER METASTASIS | Doctor of Philosophy | Doctorate | Full Time | Miss Man Ying Li |
| Date | Role | Committee | Institution | Country |
|---|---|---|---|---|
| 2026 - ongoing | Member | College of Health - Research Enablers | Adelaide University | Australia |
| 2019 - ongoing | Member | BHI IBC Biosafety Committee | BHI | Australia |
| 2018 - ongoing | Member | Basil-Hetzel Institute Management Committee | Basil-Hetzel Institute for Translational Health Research | Australia |
| 2017 - ongoing | Member | Adelaide Immunology Retreat Organzing Committee | Australasian Soceity for Immunology | Australia |
| 2017 - ongoing | Member | Day of Immunology (Adelaide) Organizing Committee | Australsian Society for Immunology | Australia |
| Date | Role | Membership | Country |
|---|---|---|---|
| 2018 - ongoing | Member | Australasian Cytometry Society | Australia |
| 2018 - ongoing | Member | Australasian Gastro-Intestinal Trials Group | Australia |
| 2018 - ongoing | Member | Cancer Voices SA | Australia |
| 2013 - ongoing | Member | Australasian Society for Immunology | Australia |
| Date | Title | Engagement Type | Institution | Country |
|---|---|---|---|---|
| 2018 - ongoing | Invited Speaker for The Longest Table Events | Public Community Engagement | The Hospital Research Foundation | Australia |
| 2018 - ongoing | Science Alive! Booth Volunteer (BHI) | Public Community Engagement | Basil Hetzel Institute for Translational Health Research | Australia |
| 2018 - ongoing | Newsletter Article in The Hospital Research Foundation | Public Community Engagement | The Hospital Research Foundation | - |
| 2018 - ongoing | Radio Interview for Coast FM | Public Community Engagement | The Hospital Research Foundation | Australia |
| 2018 - ongoing | Invited Speaker for the Day of Immunology BHI Lab Tour | Public Community Engagement | Australasian Society for Immunology | Australia |
| Date | Role | Editorial Board Name | Institution | Country |
|---|---|---|---|---|
| 2018 - 2024 | Editor | Frontiers in Cellular and Infection Microbiology | The University of Adelaide | Australia |