Higher Degree by Research Candidate
Adelaide Medical School
Faculty of Health and Medical Sciences
Kate is a PhD candidate in the Cancer Treatment Toxicities Group, supervised by A/Prof Joanne Bowen, Dr Janet Coller and Prof Rachel Gibson. She is investigating chemotherapy-induced gastrointestinal injury.
My research is focussed on understanding the role of the gut microbiome in the development of gastrointestinal toxicity following cancer treatment. I am also working to understand the interactions between the gut microbiome and the innate immune system in developing this toxicity.
Date Position Institution name 2014 - 2016 Technical Assistant University of Adelaide
Awards and Achievements
Date Type Title Institution Name Country Amount 2020 Award Young Scientist, 70th Lindau Nobel Laureate Meeting Australian Academy of Science Australia — 2020 Fellowship Adam J Berry Fellowship Awardee Australian Academy of Science and National Insititutes of Health (USA) United States — 2019 Award Outstanding Community Presentation, RAHsearch Showcase Royal Adelaide Hospital Australia — 2019 Award CSIRO ON Pitch Competition, 2nd place CSIRO Australia — 2019 Honour Falling Walls Australia, 2nd place Australian Academy of Science Australia — 2018 Award Hans-Jürgen and Maria Ohff Research Grant University of Adelaide Australia — 2017 Scholarship Lions Medical Research Foundation Inc Scholarship The University of Adelaide — — 2017 Award Lions Medical Research Foundation Inc Travel Grant — — — 2017 Scholarship Research Training Program Stipend University of Adelaide Australia — 2014 Achievement Highest Honours Grade — — — 2014 Achievement Best Honours Poster Presentation — — — 2013 Award Faculty of Sciences Outstanding Academic Achievement — — — 2012 Award Faculty of Sciences Outstanding Academic Achievement — — —
Date Institution name Country Title 2017 University of Adelaide Australia PhD in Medicine 2014 - 2014 University of Adelaide Australia Bachelor of Health Sciences (Honours) 2010 - 2014 University of Adelaide Australia Bachelor of Science (Biomedical Science)
Year Citation 2019 Bowen, J. M., Secombe, K. R., Ball, I. A., Shirren, J., Wignall, A. D., Finnie, J. W., . . . Keefe, D. (2019). Budesonide and colesevelam reduce neratinib-induced diarrhea in a rat model. In CANCER RESEARCH Vol. 79 (pp. 2 pages). San Antonio, TX: AMER ASSOC CANCER RESEARCH.
2019 Bruning, E., Coller, J., Wardill, H., Secombe, K., & Bowen, J. (2019). Toll-like receptor 4 humanized C57BL/6 mouse intestinal permeability: A translational model for cancer treatment toxicity. In JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Vol. 34 (pp. 166). WILEY. 2019 Secombe, K., Bowen, J., Ball, I., Shirren, J., Wignall, A., Lalani, A., & Diala, I. (2019). The gut microbiome as an intervention target for neratinib-induced diarrhoea. In ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY Vol. 15 (pp. 107-108). WILEY. 2018 Wardill, H., Secombe, K., Gibson, R., Stringer, A., Al-Dasooqi, N., Mayo, B., & Bowen, J. (2018). Pre-treatment blautia abundance regulates chemo-toxicity in colorectal cancer patients: A pilot study. In NEUROGASTROENTEROLOGY AND MOTILITY Vol. 30 (pp. 1 page). WILEY. 2018 Secombe, K., Bowen, J., Coller, J., Gibson, R., Stringer, A., Al-Dasooqi, N., . . . Wardill, H. R. (2018). Pre-treatment Blautia abundance regulates chemotherapy-induced gastrointestinal toxicity risk: a pilot study. In ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY Vol. 14 (pp. 59). WILEY.
Year Citation 2017 Secombe, K. R., Ball, I. A., Shirren, J., Wignall, A. D., Wardill, H. R., Van Sebille, Y. Z. A., & Bowen, J. M. (2017). Budesonide Reduces Neratinib-Induced Gastrointestinal Injury and Diarrhoea in Rats. Poster session presented at the meeting of ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY. WILEY.
Physiology IIA and IIB
Human Anatomy and Physiology IB
Integrative Cell Biology
Biology of Disease II
Foundations of Human Biology, University of South Australia
Date Role Membership Country 2016 - ongoing Member Multinational Association for Supportive Care in Cancer — 2014 - ongoing Member Australian Society of Medical Research — 2013 - ongoing Board Member Faculty of Sciences Board — 2011 - ongoing — Golden Key International Honour Society —
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