Kate Secombe

Kate Secombe
Higher Degree by Research Candidate
Adelaide Medical School
Faculty of Health and Medical Sciences

Kate is a PhD candidate in the Cancer Treatment Toxicities Group, supervised by A/Prof Joanne Bowen, Dr Janet Coller and Prof Rachel Gibson. She is investigating chemotherapy-induced gastrointestinal injury.

Connect With Me

External Profiles

Kate Secombe

Kate is a PhD candidate in the Cancer Treatment Toxicities Group, supervised by A/Prof Joanne Bowen, Dr Janet Coller and Prof Rachel Gibson. She is investigating chemotherapy-induced gastrointestinal injury.

Appointments

Date Position Institution name
2014 - 2016 Technical Assistant University of Adelaide

Awards and Achievements

Date Type Title Institution Name Amount
2017 Research Training Program Stipend
2014 Highest Honours Grade
2014 Best Honours Poster Presentation
2013 Faculty of Sciences Outstanding Academic Achievement
2012 Faculty of Sciences Outstanding Academic Achievement

Education

Date Institution name Country Title
2017 University of Adelaide Australia PhD in Medicine
2014 - 2014 University of Adelaide Australia Bachelor of Health Sciences (Honours)
2010 - 2014 University of Adelaide Australia Bachelor of Science (Biomedical Science)

Journals

Year Citation
2017 Coller, J., Bowen, J., Ball, I., Wardill, H., van Sebille, Y., Stansborough, R. ... Gibson, R. (2017). Potential safety concerns of TLR4 antagonism with irinotecan: a preclinical observational report. Cancer Chemotherapy and Pharmacology, 79, 2, 431-434. 10.1007/s00280-016-3223-3
2017 Van Sebille, Y., Gibson, R., Wardill, H., Secombe, K., Ball, I., Keefe, D. ... Bowen, J. (2017). Dacomitinib-induced diarrhoea is associated with altered gastrointestinal permeability and disruption in ileal histology in rats. International Journal of Cancer, 140, 12, 2820-2829. 10.1002/ijc.30699
2016 Wardill, H., Gibson, R., Van Sebille, Y., Secombe, K., Logan, R. & Bowen, J. (2016). A novel in vitro platform for the study of SN38-induced mucosal damage and the development of Toll-like receptor 4-targeted therapeutic options. Experimental Biology and Medicine, 241, 13, 1386-1394. 10.1177/1535370216640932
2016 Wardill, H., Bowen, J., Van Sebille, Y., Secombe, K., Coller, J., Ball, I. ... Gibson, R. (2016). TLR4-dependent claudin-1 internalization and secretagogue-mediated chloride secretion regulate irinotecan-induced diarrhea. Molecular Cancer Therapeutics, 15, 11, 2767-2779. 10.1158/1535-7163.MCT-16-0330
2016 Wardill, H., Gibson, R., Van Sebille, Y., Secombe, K., Coller, J., White, I. ... Bowen, J. (2016). Irinotecan-induced gastrointestinal dysfunction and pain are mediated by common TLR4-dependent mechanisms. Molecular Cancer Therapeutics, 15, 6, 1376-1386. 10.1158/1535-7163.MCT-15-0990

Memberships

Date Role Membership Country
2016 - ongoing Member Multinational Association for Supportive Care in Cancer
2014 - ongoing Member Australian Society of Medical Research
2013 - ongoing Board Member Faculty of Sciences Board
2011 - ongoing Golden Key International Honour Society

top