Kate Secombe

Kate Secombe
Higher Degree by Research Candidate
Adelaide Medical School
Faculty of Health and Medical Sciences

Kate is a PhD candidate in the Cancer Treatment Toxicities Group, supervised by A/Prof Joanne Bowen, Dr Janet Coller and Prof Rachel Gibson. She is investigating chemotherapy-induced gastrointestinal injury.

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Kate Secombe

Kate is a PhD candidate in the Cancer Treatment Toxicities Group, supervised by A/Prof Joanne Bowen, Dr Janet Coller and Prof Rachel Gibson. She is investigating chemotherapy-induced gastrointestinal injury.

Appointments

Date Position Institution name
2014 - 2016 Technical Assistant University of Adelaide

Awards and Achievements

Date Type Title Institution Name Country Amount
2017 Scholarship Research Training Program Stipend Anguilla
2017 Scholarship Lions Medical Research Foundation Inc Scholarship The University of Adelaide
2017 Award Lions Medical Research Foundation Inc Travel Grant
2014 Achievement Highest Honours Grade
2014 Achievement Best Honours Poster Presentation
2013 Award Faculty of Sciences Outstanding Academic Achievement
2012 Award Faculty of Sciences Outstanding Academic Achievement

Education

Date Institution name Country Title
2017 University of Adelaide Australia PhD in Medicine
2014 - 2014 University of Adelaide Australia Bachelor of Health Sciences (Honours)
2010 - 2014 University of Adelaide Australia Bachelor of Science (Biomedical Science)

Journals

Year Citation
2017 Van Sebille, Y., Gibson, R., Wardill, H., Secombe, K., Ball, I., Keefe, D., . . . Bowen, J. (2017). Dacomitinib-induced diarrhoea is associated with altered gastrointestinal permeability and disruption in ileal histology in rats. International Journal of Cancer, 140(12), 2820-2829.
DOI Scopus1 WoS1 Europe PMC1
2017 Coller, J., Bowen, J., Ball, I., Wardill, H., van Sebille, Y., Stansborough, R., . . . Gibson, R. (2017). Potential safety concerns of TLR4 antagonism with irinotecan: a preclinical observational report. Cancer Chemotherapy and Pharmacology, 79(2), 431-434.
DOI
2016 Wardill, H., Gibson, R., Van Sebille, Y., Secombe, K., Logan, R., & Bowen, J. (2016). A novel in vitro platform for the study of SN38-induced mucosal damage and the development of Toll-like receptor 4-targeted therapeutic options. Experimental Biology and Medicine, 241(13), 1386-1394.
DOI Scopus3 WoS3 Europe PMC2
2016 Wardill, H., Gibson, R., Van Sebille, Y., Secombe, K., Coller, J., White, I., . . . Bowen, J. (2016). Irinotecan-induced gastrointestinal dysfunction and pain are mediated by common TLR4-dependent mechanisms. Molecular Cancer Therapeutics, 15(6), 1376-1386.
DOI Scopus11 WoS11 Europe PMC8
2016 Wardill, H., Bowen, J., Van Sebille, Y., Secombe, K., Coller, J., Ball, I., . . . Gibson, R. (2016). TLR4-dependent claudin-1 internalization and secretagogue-mediated chloride secretion regulate irinotecan-induced diarrhea. Molecular Cancer Therapeutics, 15(11), 2767-2779.
DOI Scopus3 WoS3 Europe PMC2

Memberships

Date Role Membership Country
2016 - ongoing Member Multinational Association for Supportive Care in Cancer
2014 - ongoing Member Australian Society of Medical Research
2013 - ongoing Board Member Faculty of Sciences Board
2011 - ongoing Golden Key International Honour Society
Email
kate.secombe@adelaide.edu.au
Campus
North Terrace
Building
Helen Mayo South Building
Org Unit
Faculty of Health and Medical Sciences

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