Higher Degree by Research Candidate
Adelaide Medical School
Faculty of Health and Medical Sciences
Kate is a PhD candidate in the Cancer Treatment Toxicities Group, supervised by A/Prof Joanne Bowen, Dr Janet Coller and Prof Rachel Gibson. She is investigating chemotherapy-induced gastrointestinal injury.
Date Position Institution name 2014 - 2016 Technical Assistant University of Adelaide
Awards and Achievements
Date Type Title Institution Name Country Amount 2018 Award Hans-Jürgen and Maria Ohff Research Grant University of Adelaide Australia — 2017 Scholarship Lions Medical Research Foundation Inc Scholarship The University of Adelaide — — 2017 Award Lions Medical Research Foundation Inc Travel Grant — — — 2017 Scholarship Research Training Program Stipend — Anguilla — 2014 Achievement Highest Honours Grade — — — 2014 Achievement Best Honours Poster Presentation — — — 2013 Award Faculty of Sciences Outstanding Academic Achievement — — — 2012 Award Faculty of Sciences Outstanding Academic Achievement — — —
Date Institution name Country Title 2017 University of Adelaide Australia PhD in Medicine 2014 - 2014 University of Adelaide Australia Bachelor of Health Sciences (Honours) 2010 - 2014 University of Adelaide Australia Bachelor of Science (Biomedical Science)
Year Citation 2019 Secombe, K., Ball, I., Shirren, J., Wignall, A., Finnie, J., Keefe, D., . . . Bowen, J. (2019). Targeting neratinib-induced diarrhea with budesonide and colesevelam in a rat model. Cancer Chemotherapy and Pharmacology, 83(3), 531-543.
2019 Wardill, H., Secombe, K., Bryant, R., Hazenberg, M., & Costello, S. (2019). Adjunctive fecal microbiota transplantation in supportive oncology: emerging indications and considerations in immunocompromised patients. EBioMedicine, 44, 730-740.
DOI Scopus3 WoS1 Europe PMC2
2018 Secombe, K., Coller, J., Gibson, R., Wardill, H., & Bowen, J. (2018). The bidirectional interaction of the gut microbiome and the innate immune system: Implications for chemotherapy‐induced gastrointestinal toxicity. International Journal of Cancer, 144(10), 2365-2376.
DOI Scopus4 WoS3 Europe PMC1
2017 Van Sebille, Y., Gibson, R., Wardill, H., Secombe, K., Ball, I., Keefe, D., . . . Bowen, J. (2017). Dacomitinib-induced diarrhoea is associated with altered gastrointestinal permeability and disruption in ileal histology in rats. International Journal of Cancer, 140(12), 2820-2829.
DOI Scopus8 WoS6 Europe PMC3
2017 Coller, J., Bowen, J., Ball, I., Wardill, H., van Sebille, Y., Stansborough, R., . . . Gibson, R. (2017). Potential safety concerns of TLR4 antagonism with irinotecan: a preclinical observational report. Cancer Chemotherapy and Pharmacology, 79(2), 431-434.
DOI Scopus3 WoS3 Europe PMC1
2016 Wardill, H., Gibson, R., Van Sebille, Y., Secombe, K., Logan, R., & Bowen, J. (2016). A novel in vitro platform for the study of SN38-induced mucosal damage and the development of Toll-like receptor 4-targeted therapeutic options. Experimental Biology and Medicine, 241(13), 1386-1394.
DOI Scopus5 WoS6 Europe PMC3
2016 Wardill, H., Gibson, R., Van Sebille, Y., Secombe, K., Coller, J., White, I., . . . Bowen, J. (2016). Irinotecan-induced gastrointestinal dysfunction and pain are mediated by common TLR4-dependent mechanisms. Molecular Cancer Therapeutics, 15(6), 1376-1386.
DOI Scopus28 WoS25 Europe PMC11
2016 Wardill, H., Bowen, J., Van Sebille, Y., Secombe, K., Coller, J., Ball, I., . . . Gibson, R. (2016). TLR4-dependent claudin-1 internalization and secretagogue-mediated chloride secretion regulate irinotecan-induced diarrhea. Molecular Cancer Therapeutics, 15(11), 2767-2779.
DOI Scopus9 WoS10 Europe PMC5
Practical Demonstrator, Physiology IIA and IIB
Guest Lecturer, Integrative Cell Biology
Online Tutor, Foundations of Human Biology, University of South Australia
Date Role Membership Country 2016 - ongoing Member Multinational Association for Supportive Care in Cancer — 2014 - ongoing Member Australian Society of Medical Research — 2013 - ongoing Board Member Faculty of Sciences Board — 2011 - ongoing — Golden Key International Honour Society —
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