Professor Julie Owens

Julie Owens
Acting Deputy Vice-Chancellor (Research)
Office of the Deputy Vice-Chancellor and Vice-President (Research)
Division of Research and Innovation

I was previously the inaugural Head of the School of Paediatrics and Reproductive Health and Associate Dean Research in the Faculty of Health Sciences and earlier, the Head of Discipline of Physiology and Associate Dean Research in the Faculty of Sciences.

I joined the University as an ARC QEII Fellow and subsequently an NHMRC Research Fellow, engaged in research into pregnancy and fetal and placental functional development. This continues, extending to the early life programming of obesity and cardio-metabolic health of offspring by paternal and maternal obesity and diabetes and other exposures, funded by NIH, NHMRC, ARC, DART and other bodies.

I am Deputy President of the scientific society. Development Origins of Health and Disease ANZ, which I helped establish recently as a chapter of the international society. I also helped establish links with and currently participate in various international research collaborations, including the EU EarlyNutrition FP7-Funded Research Program, the MRC University of Bristol Integrative Epidemiology Unit and the International Weight Management in Pregnancy Consortia.

Professor Julie Owens

I was previously the inaugural Head of the School of Paediatrics and Reproductive Health and Associate Dean Research in the Faculty of Health Sciences and earlier, the Head of Discipline of Physiology and Associate Dean Research in the Faculty of Sciences.

I joined the University as an ARC QEII Fellow and subsequently an NHMRC Research Fellow, engaged in research into pregnancy and fetal and placental functional development. This continues, extending to the early life programming of obesity and cardio-metabolic health of offspring by paternal and maternal obesity and diabetes and other exposures, funded by NIH, NHMRC, ARC, DART and other bodies.

I am Deputy President of the scientific society. Development Origins of Health and Disease ANZ, which I helped establish recently as a chapter of the international society. I also helped establish links with and currently participate in various international research collaborations, including the EU EarlyNutrition FP7-Funded Research Program, the MRC University of Bristol Integrative Epidemiology Unit and the International Weight Management in Pregnancy Consortia.

Early Origins of Health and Disease

Our Research Group

We are part of the Early Origins of Health Theme in the Robinson Research Insitute, international leaders in the investigation of the intergenerational and perinatal origins of cardio-metabolic and neurological health in postnatal life.

Our research program focuses on those aspects of health that are profoundly influenced by events in early life and possibly in previous generations, including diabetes, obesity and cancer risk.

Our aims are to:

  • Understand how common exposures in early life affect our later health, including 
    • Placental and fetal growth restriction
    • Maternal vitamin supplementation such as folic acid 
    • Maternal and paternal obesity and diabetes 
  • The mechanisms involved including how these early life exposures interact with the genome and affect the epigenome to determine our later health
  • Identify interventions to either prevent the conditions that initiate programming of our later health or to overcome or reverse such programming, including 
    • Maternal growth hormone treatment
    • Maternal dietary supplements; arginine, folic acid and methyl nutrients.

Recent discoveries include:

  • Placental restriction 
    • Inducing diabetes in adult offspring via impaired beta cell function and growth and insulin resistance
    • Obesity in offspring via altered appetite control
    • Altering expression on novel small regulatory RNAs that can target and repress expression of multiple mRNAs to affect major pathways in glucoregulatory tissues
  • Maternal folic acid supplementation or dietary folate and methyl nutrient deficiency in rodents changing the epigenome and the physiology of offpring.

We utilise a range of experimental paradigms in non-human species to investigate the molecular, genetic and epigenetic basis of early life programming of health and disease.  We also collaborate with our clinical and epidemiological colleagues in complementary studies in humans.

The current research programs are:

  • Early life programming of diabetes and obesity by fetal growth restriction, maternal or paternal obesity
  • Functional and epigenetic consequences of maternal micro and macronutrient deficiencies for metabolic function and cancer risk of offspring
  • Micronutrient, dietary and other interventions in mother and offspring to overcome placental programming of metabolic disease
  • Efficacy of micronutrient and other interventions in mother and offspring and their molecular and epigenetic basis.

Research funding acknowledgements

Our work is funded by National Health and Medical Research Council, Diabetes Australia Trust, CRC for an Internationally Competitive Pork Industry, Channel 7 Children's Research Foundation, Group of Eight/DAAD Australian-German Research Co-operation Scheme and National Institutes of Health. 

Appointments

Date Position Institution name
2017 Acting Deputy Vice-Chancellor (Research) University of Adelaide, Adelaide
2015 Pro Vice-Chancellor - Research Strategy University of Adelaide
2009 - 2015 Associate Dean Research, Faculty of Health Sciences University of Adelaide
2006 - 2015 Head (Inaugural), School of Paediatrics and Reproductive Health University of Adelaide
2004 Professor, School of Paediatrics and Reproductive Health University of Adelaide
2004 Director, Theme (Research Centre) for Early Origins of Health University of Adelaide

Awards and Achievements

Date Type Title Institution Name Amount
2000 The Molley Towell Lecturer Western Perinatal Society
1999 Elected Fellow Perinatal Research Society
1999 The McCance Medal, for outstanding contributions to perinatal research The Neonatal Society, Royal Society of Medicine
1989 National Health and Medical Research Council Research Fellowship(s) (two) National Health and Medical Research Council
1987 Australian Research Council Queen Elizabeth II Post-doctoral Research Fellowship Australian Research Council
1978 Campion Ma Playoust Memorial Award Australian Society for Medical Research

Education

Date Institution name Country Title
1983 University of Queensland Australia PhD
1974 University of Queensland Australia BSc Hons

Journals

Year Citation
2017 Dodd, J., Du Plessis, L., Deussen, A., Grivell, R., Yelland, L., Louise, J. ... Owens, J. (2017). Paternal obesity modifies the effect of an antenatal lifestyle intervention in women who are overweight or obese on newborn anthropometry. Scientific Reports, 7, 1, 1557-1-1557-9. 10.1038/s41598-017-01672-w
2017 Vranas, S., Heinemann, G., Liu, H., De Blasio, M., Owens, J., Gatford, K. & Black, M. (2017). Small size at birth predicts decreased cardiomyocyte number in the adult ovine heart. Journal of Developmental Origins of Health and Disease, 1-8. 10.1017/S2040174417000381
2017 Hunter, D., Hazel, S., Kind, K., Liu, H., Marini, D., Giles, L. ... Gatford, K. (2017). Effects of induced placental and fetal growth restriction, size at birth and early neonatal growth on behavioural and brain structural lateralization in sheep. Laterality, 22, 5, 560-589. 10.1080/1357650X.2016.1243552
2017 De Matteo, R., Hodgson, D., Bianco-Miotto, T., Nguyen, V., Owens, J., Harding, R. ... Gatford, K. (2017). Betamethasone-exposed preterm birth does not impair insulin action in adult sheep.. Journal of Endocrinol, 232, 2, 175-187. 10.1530/JOE-16-0300
2017 Singh, M., Thomas, P., Hor, M., Almond, T., Owens, J., Hague, W. & Fenech, M. (2017). Infant birth outcomes are associated with DNA damage biomarkers as measured by the cytokinesis block micronucleus cytome assay: The DADHI study. Mutagenesis, 32, 3, 355-370. 10.1093/mutage/gex001
2017 Moran, L., Fraser, L., Sundernathan, T., Deussen, A., Louise, J., Yelland, L. ... Dodd, J. (2017). The effect of an antenatal lifestyle intervention in overweight and obese women on circulating cardiometabolic and inflammatory biomarkers: secondary analyses from the LIMIT randomised trial. BMC Medicine, 15, 1, 1-12. 10.1186/s12916-017-0790-z
2017 Sulaiman, S. A., De Blasio, M. J., Harland, M. L., Gatford, K. L. & Owens, J. A. (2017). Maternal methyl donor and cofactor supplementation in late pregnancy increases β-cell numbers at 16 days of life in growth-restricted twin lambs.. American journal of physiology. Endocrinology and metabolism, ajpendo.00033.2017-. 10.1152/ajpendo.00033.2017
2017 Rogozińska, E., Marlin, N., Jackson, L., Rayanagoudar, G., Ruifrok, A., Dodds, J. ... Shub, A. (2017). Effects of antenatal diet and physical activity on maternal and fetal outcomes: Individual patient data meta-analysis and health economic evaluation. Health Technology Assessment, 21, 41, 1-+. 10.3310/hta21410
2017 Dodd, J., Grivell, R., Louise, J., Deussen, A., Giles, L., Mol, B. ... Owens, J. (2017). The effects of dietary and lifestyle interventions among pregnant women who are overweight or obese on longer-term maternal and early childhood outcomes: Protocol for an individual participant data (IPD) meta-analysis. Systematic Reviews, 6, 1, 51-. 10.1186/s13643-017-0442-6
2017 McPherson, N., Lane, M., Sandeman, L., Owens, J. & Fullston, T. (2017). An exercise-only intervention in obese fathers restores glucose and insulin regulation in conjunction with the rescue of pancreatic islet cell morphology and microRNA expression in male offspring. Nutrients, 9, 2, 122-1-122-17. 10.3390/nu9020122
2017 International Weight Management in Pregnancy (i-WIP) Collaborative Group, (2017). Effect of diet and physical activity based interventions in pregnancy on gestational weight gain and pregnancy outcomes: meta-analysis of individual participant data from randomised trials. BMJ Open, 358, 3119, 1-15. 10.1136/bmj.j3119
2017 Horton, D., Saint, D., Owens, J., Gatford, K. & Kind, K. (2017). Use of the hyperinsulinemic euglycemic clamp to assess insulin sensitivity in guinea pigs: Dose response, partitioned glucose metabolism, and species comparisons. American Journal of Physiology - Regulatory Integrative and Comparative Physiology, 313, 1, 19-28. 10.1152/ajpregu.00028.2017
2017 Owens, J. (2017). Effect of diet and physical activity based interventions in pregnancy on gestational weight gain and pregnancy outcomes: meta-analysis of individual participant data from randomised trials. BMJ, j3991-j3991. 10.1136/bmj.j3991
2016 Dodd, J., Newman, A., Moran, L., Deussen, A., Grivell, R., Yelland, L. ... Robinson, J. (2016). The effect of antenatal dietary and lifestyle advice for women who are overweight or obese on emotional well-being: the LIMIT randomized trial. Acta Obstetricia et Gynecologica Scandinavica, 95, 3, 309-318. 10.1111/aogs.12832
2016 McPherson, N., Fullston, T., Kang, W., Sandeman, L., Corbett, M., Owens, J. & Lane, M. (2016). Paternal under-nutrition programs metabolic syndrome in offspring which can be reversed by antioxidant/vitamin food fortification in fathers. Scientific Reports, 6, 1, 1-14. 10.1038/srep27010
2016 Dodd, J., Deussen, A., Mohamad, I., Rifas-Shiman, S., Yelland, L., Louise, J. ... Robinson, J. (2016). The effect of antenatal lifestyle advice for women who are overweight or obese on secondary measures of neonatal body composition: The LIMIT randomised trial. BJOG: An International Journal of Obstetrics and Gynaecology, 123, 2, 244-253. 10.1111/1471-0528.13796
2016 Flynn, A., Dalrymple, K., Barr, S., Poston, L., Goff, L., Rogozińska, E. ... Scudeller, T. (2016). Dietary interventions in overweight and obese pregnant women: A systematic review of the content, delivery, and outcomes of randomized controlled trials. Nutrition Reviews, 74, 5, 312-328. 10.1093/nutrit/nuw005
2016 Hunter, D., Hazel, S., Kind, K., Owens, J., Pitcher, J. & Gatford, K. (2016). Programming the brain: common outcomes and gaps in knowledge from animal studies of IUGR. Physiology & Behavior, 164, A, 233-248. 10.1016/j.physbeh.2016.06.005
2016 Horton, D., Saint, D., Owens, J., Kind, K. & Gatford, K. (2016). Spontaneous intrauterine growth restriction due to increased litter size in the Guinea pig programmes postnatal growth, appetite and adult body composition. Journal of Developmental Origins of Health and Disease, 7, 5, 548-562. 10.1017/S2040174416000295
2015 McPherson, N. O., Owens, J. A., Fullston, T. & Lane, M. (2015). Preconception diet or exercise interventions in obese fathers normalizes sperm microRNA profile and metabolic syndrome in female offspring. American journal of physiology: Endocrinology and metabolism, 308, 9, E805-E821. 10.1152/ajpendo.00013.2015
2015 Quigley, S. P., Greenwood, P. L., Kleemann, D. O., Owens, J. A., Bawden, C. S. & Nattrass, G. S. (2015). Myogenesis in small and large ovine fetuses at three stages of pregnancy. Animal Production Science, 55, 2, 207-212. 10.1071/AN14203
2015 Campbell, J., Lane, M., Owens, J. & Bakos, H. (2015). Paternal obesity negatively affects male fertility and assisted reproduction outcomes: a systematic review and meta-analysis. Reproductive BioMedicine Online, 31, 5, 593-604. 10.1016/j.rbmo.2015.07.012
2015 Maftei, O., Whitrow, M., Davies, M., Giles, L., Owens, J. & Moore, V. (2015). Maternal body size prior to pregnancy, gestational diabetes and weight gain: associations with insulin resistance in children at 9-10 years. Diabetic Medicine, 32, 2, 174-180. 10.1111/dme.12637
2015 Hunter, D., Hazel, S., Kind, K., Liu, H., Marini, D., Owens, J. ... Gatford, K. (2015). Do I turn left or right? Effects of sex, age, experience and exit route on maze test performance in sheep. Physiology and Behavior, 139, 244-253. 10.1016/j.physbeh.2014.11.037
2015 Singh, M., Thomas, P., Owens, J., Hague, W. & Fenech, M. (2015). Potential role of folate in pre-eclampsia. Nutrition Reviews, 73, 10, 694-722. 10.1093/nutrit/nuv028
2015 Liu, H., Schultz, C., De Blasio, M., Peura, A., Heinemann, G., Harryanto, H. ... Gatford, K. (2015). Effect of placental restriction and neonatal exendin-4 treatment on postnatal growth, adult body composition and in vivo glucose metabolism in the sheep. American Journal of Physiology, Endocrinology and Metabolism, 309, 6, E589-E600. 10.1152/ajpendo.00487.2014
2015 Ruifrok, A., Rogozinska, E., van Poppel, M., Rayanagoudar, G., Kerry, S., de Groot, C. ... Tonstad, S. (2015). Erratum to Study protocol: Differential effects of diet and physical activity based interventions in pregnancy on maternal and fetal outcomes: Individual patient data (IPD) meta-analysis and health economic evaluation [Syst Rev., 3, 131, (2014)]. Systematic Reviews, 4, 1, 101-. 10.1186/s13643-015-0079-2
2015 Standen, P., Sferruzzi-Perri, A., Taylor, R., Heinemann, G., Zhang, J., Highet, A. ... Roberts, C. (2015). Maternal insulin-like growth factor 1 and 2 differentially affect the renin-angiotensin system during pregnancy in the guinea pig. Growth Hormone & IGF Research, 25, 3, 141-147. 10.1016/j.ghir.2015.02.001
2015 Fullston, T., McPherson, N., Owens, J., Kang, W., Sandeman, L. & Lane, M. (2015). Paternal obesity induces metabolic and sperm disturbances in male offspring that are exacerbated by their exposure to an "obesogenic" diet. Physiological Reports, 3, 3, e12336-1-e12336-14. 10.14814/phy2.12336
2015 Dodd, J., Kannieappan, L., Grivell, R., Deussen, A., Moran, L., Yelland, L. & Owens, J. (2015). Effects of an antenatal dietary intervention on maternal anthropometric measures in pregnant women with obesity. Obesity, 23, 8, 1555-1562. 10.1002/oby.21145
2015 Dodd, J., Ahmed, S., Karnon, J., Umberger, W., Deussen, A., Tran, T. ... Robinson, J. (2015). The cost-effectiveness of providing antenatal lifestyle advice for women who are overweight or obese: the LIMIT randomised trial. BMC Obesity, 2, 1, 14-1-14-9. 10.1186/s40608-015-0046-4
2015 Hunter, D., Hazel, S., Kind, K., Liu, H., Marini, D., Giles, L. ... Gatford, K. (2015). Placental and foetal growth restriction, size at birth and neonatal growth alter cognitive function and behaviour in sheep in an age- and sex-specific manner. Physiology & Behavior, 152, A, 1-10. 10.1016/j.physbeh.2015.08.042
2014 Wooldridge, A., Bischof, R., Meeusen, E., Liu, H., Heinemann, G., Hunter, D. ... Gatford, K. (2014). Placental restriction of fetal growth reduces cutaneous responses to antigen after sensitization in sheep. American Journal of Physiology, Regulatory, Integrative and Comparative Physiology, 306, 7, R441-R446. 10.1152/ajpregu.00432.2013
2014 Dodd, J., Turnbull, D., McPhee, A., Deussen, A., Grivell, R., Yelland, L. ... Robinson, J. (2014). Antenatal lifestyle advice for women who are overweight or obese: LIMIT randomised trial. BMJ, 348, 3, 1-12. 10.1136/bmj.g1285
2014 Ng, S., Lin, R., Maloney, C., Youngson, N., Owens, J. & Morris, M. (2014). Paternal high-fat diet consumption induces common changes in the transcriptomes of retroperitoneal adipose and pancreatic islet tissues in female rat offspring. The FASEB Journal, 28, 4, 1830-1841. 10.1096/fj.13-244046
2014 Dodd, J. M., Turnbull, D., McPhee, A. J., Deussen, A. R., Grivell, R. M., Yelland, L. N. ... Robinson, J. S. (2014). Antenatal lifestyle advice for women who are overweight or obese: LIMIT randomised trial. Obstetrical and Gynecological Survey, 69, 6, 311-313. 10.1097/01.ogx.0000451478.28533.cf
2014 Dodd, J., McPhee, A., Turnbull, D., Yelland, L., Deussen, A., Grivell, R. ... Robinson, J. (2014). The effects of antenatal dietary and lifestyle advice for women who are overweight or obese on neonatal health outcomes: the LIMIT randomised trial. BMC Medicine, 12, 1, 163-1-163-9. 10.1186/s12916-014-0163-9
2014 Dodd, J. M., Grivell, R. M. & Owens, J. A. (2014). Antenatal Dietary and Lifestyle Interventions for Women Who are Overweight or Obese: Outcomes from the LIMIT Randomized Trial. Current Nutrition Reports, 3, 4, 392-399. 10.1007/s13668-014-0101-7
2014 Dodd, J. M., Cramp, C., Sui, Z., Yelland, L. N., Deussen, A. R., Grivell, R. M. ... Robinson, J. S. (2014). The effects of antenatal dietary and lifestyle advice for women who are overweight or obese on maternal diet and physical activity: the LIMIT randomised trial. BMC Medicine, 12, 1, 161-1-161-19. 10.1186/s12916-014-0161-y
2014 Gatford, K., Heinemann, G., Thompson, S., Zhang, J., Buckberry, S., Owens, J. ... Roberts, C. (2014). Circulating IGF1 and IGF2 and SNP genotypes in men and pregnant and non-pregnant women. Endocrine Connections, 3, 3, 138-149. 10.1530/EC-14-0068
2013 Fullston, T., Ohlsson Teague, E., Mc Pherson, N., De Blasio, M., Mitchell, M., Corbett, M. ... Lane, M. (2013). Paternal obesity initiates metablic disturbances in two generations of mice with incomplete penetrance to the F₂ generation and alters the transcriptional profile of testis and sperm microRNA content. FASEB Journal, 27, 10, 4226-4243. 10.1096/fj.12-224048
2013 Gatford, K., Houda, C., Lu, Z., Coat, S., Baghurst, P., Owens, J. ... Hague, W. (2013). Vitamin B12 and homocysteine status during pregnancy in the metformin in gestational diabetes trial: responses to maternal metformin compared with insulin treatment. Diabetes Obesity & Metabolism, 15, 7, 660-667. 10.1111/dom.12080
2013 Gatford, K., Sulaiman, S., Mohammad, S., De Blasio, M., Harland, M., Simmons, R. & Owens, J. (2013). Neonatal exendin-4 reduces growth, fat deposition and glucose tolerance during treatment in the intrauterine growth-restricted lamb. PLoS One, 8, 2, 1-10. 10.1371/journal.pone.0056553
2013 Whitrow, M., Davies, M., Giles, L., De Stavola, B., Owens, J., Maftei, O. & Moore, V. (2013). Effects of birth size, post-natal growth and current size on insulin resistance in 9-year-old children: a prospective cohort study. European Journal of Pediatrics, 172, 9, 1207-1214. 10.1007/s00431-013-2017-4
2013 Barrett, H., Gatford, K., Houda, C., De Blasio, M., McIntyre, H., Callaway, L. ... Rowan, J. (2013). Maternal and neonatal circulating markers of metabolic and cardiovascular risk in the Metformin in Gestational Diabetes (MiG) trial: Responses to maternal metformin versus insulin treatment. Diabetes Care, 36, 3, 529-536. 10.2337/dc12-1097
2013 Barrett, H., Nitert, M., Jones, L., O'Rourke, P., Lust, K., Gatford, K. ... Rowan, J. (2013). Determinants of maternal triglycerides in women with gestational diabetes mellitus in the Metformin in Gestational Diabetes (MiG) study. Diabetes Care, 36, 7, 1941-1946. 10.2337/dc12-2132
2013 Mc Pherson, N., Bakos, H., Owens, J., Setchell, B. & Lane, M. (2013). Improving metabolic health in obese male mice via diet and exercise restores embryo development and fetal growth. PLoS One, 8, 8, 1-10. 10.1371/journal.pone.0071459
2012 Tung, E., Roberts, C., Heinemann, G., De Blasio, M., Kind, K., Van Wettere, W. ... Gatford, K. (2012). Increased placental nutrient transporter expression at mid-gestation after maternal growth hormone treatment in pigs: A placental mechanism for increased fetal growth. Biology of Reproduction, online, 5, 1-17. 10.1095/biolreprod.112.100222
2012 De Blasio, M., Gatford, K., Harland, M., Robinson, J. & Owens, J. (2012). Placental restriction reduces insulin sensitivity and expression of insulin signaling and glucose transporter genes in skeletal muscle, but not liver, in young sheep. Endocrinology, 153, 5, 2142-2151. 10.1210/en.2011-1955
2012 Gatford, K., De Blasio, M., How, T., Harland, M., Pearce, B. & Owens, J. (2012). Testing the plasticity of insulin secretion and β-cell function in vivo: responses to chronic hyperglycaemia in the sheep. Experimental Physiology, 97, 5, 663-675. 10.1113/expphysiol.2011.063560
2012 Chen, M., Macpherson, A., Owens, J., Wittert, G. & Heilbronn, L. (2012). Obesity alone or with type 2 diabetes is associated with tissue specific alterations in DNA methylation and gene expression of PPARGC1A and IGF2. Journal of Diabetic Research & Clinical Metabolism, 2012, 1, 1-8. 10.7243/2050-0866-1-16
2012 Kennaway, D., Owens, J., Voultsios, A. & Wight, N. (2012). Adipokines and adipocyte function in clock mutant mice that retain melatonin rhythmicity. Obesity, 20, 2, 295-305. 10.1038/oby.2011.276
2012 Gatford, K., Smits, R., Collins, C., De Blasio, M., Roberts, C., Nottle, M. ... Owens, J. (2012). Maternal low-dose porcine somatotropin treatment in late gestation increases progeny weight at birth and weaning in sows but not in gilts. Journal of Animal Science, 90, 5, 1428-1435. 10.2527/jas.2011-4227
2012 Mc Pherson, N., Bakos, H., Owens, J., Setchell, B. & Lane, M. (2012). Diet and exercise in an obese mouse fed a high-fat diet improve metabolic health and reverse perturbed sperm function. American Journal of Physiology-Endocrinology and Metabolism, 302, 7, E768-E780. 10.1152/ajpendo.00401.2011
2012 Fullston, T., Mc Pherson, N., Owens, J., Mitchell, M., Bakos, H. & Lane, M. (2012). Diet-induced paternal obesity in the absence of diabetes diminishes the reproductive health of two subsequent generations of mice. Human Reproduction, 27, 5, 1391-1400. 10.1093/humrep/des030
2011 Pitcher, J., Schneider, L., Drysdale, J., Ridding, M. & Owens, J. (2011). Motor system development of the preterm and low birthweight infant. Clinics in Perinatology, 38, 4, 605-625. 10.1016/j.clp.2011.08.010
2011 Smith, G., Konycheva, G., Dziadek, M., Ravelich, S., Patel, S., Reddy, S. ... Ferguson, L. (2011). Pre- and postnatal methyl deficiency in the rat differentially alters glucose homeostasis. Journal of Nutrigenetics and Nutrigenomics, 4, 4, 175-191. 10.1159/000330227
2011 Knelangen, J., Van der Hoek, M., Kong, W., Owens, J., Fischer, B. & Santos, A. (2011). MicroRNA expression profile during adipogenic differentiation in mouse embryonic stem cells. Physiological Genomics, 43, 10, 611-620. 10.1152/physiolgenomics.00116.2010
2011 Sferruzzi-Perri, A., Owens, J., Pringle, K. & Roberts, C. (2011). The neglected role of insulin-like growth factors in the maternal circulation regulating fetal growth. Journal of Physiology-London, 589, 1, 7-20. 10.1113/jphysiol.2010.198622
2010 Gatford, K., Smits, R., Collins, C., Argent, C., De Blasio, M., Roberts, C. ... Owens, J. (2010). Maternal responses to daily maternal porcine somatotropin injections during early-mid pregnancy or early-late pregnancy in sows and gilts. Journal of Animal Science, 88, 4, 1365-1378. 10.2527/jas.2009-2265
2010 De Blasio, M., Blache, D., Gatford, K., Robinson, J. & Owens, J. (2010). Placental restriction increases adipose leptin gene expression and plasma leptin and alters their relationship to feeding activity in the young lamb. Pediatric Research, 67, 6, 603-608. 10.1203/PDR.0b013e3181dbc471
2010 Gatford, K., Simmons, R., De Blasio, M., Robinson, J. & Owens, J. (2010). Placental programming of postnatal diabetes and impaired insulin action after IUGR. Placenta, 31, SUPPL., S60-S65. 10.1016/j.placenta.2009.12.015
2010 Siebel, A., Gallo, J., Guan, T., Owens, J. & Wlodek, M. (2010). Cross-fostering and improved lactation ameliorates deficits in endocrine pancreatic morphology in growth-restricted adult male rat offspring. Journal of Developmental Origins of Health and Disease, 1, 4, 234-244. 10.1017/S2040174410000383
2010 Micke, G., Sullivan, T., Gatford, K., Owens, J. & Perry, V. (2010). Nutrient intake in the bovine during early and mid-gestation causes sex-specific changes in progeny plasma IGF-I, liveweight, height and carcass traits. Animal Reproduction Science, 121, 3-4, 208-217. 10.1016/j.anireprosci.2010.05.017
2010 Ng, S., Lin, R., Laybutt, D., Barres, R., Owens, J. & Morris, M. (2010). Chronic high-fat diet in fathers programs β-cell dysfunction in female rat offspring. Nature, 467, 7318, 963-U103. 10.1038/nature09491
2009 Sullivan, T., Micke, G., Perkins, N., Martin, G., Wallace, C., Gatford, K. ... Perry, V. (2009). Dietary protein during gestation affects maternal IGF, IGFBP, leptin concentrations, and fetal growth in heifers. Journal of Animal Science, 87, 10, 3304-3316. 10.2527/jas.2008-1753
2009 Moritz, K., Mazzuca, M., Siebel, A., Mibus, A., Arena, D., Tare, M. ... Wlodek, M. (2009). Uteroplacental insufficiency causes a nephron deficit, modest renal insufficiency but no hypertension with ageing in female rats. Journal of Physiology-London, 587, 11, 2635-2646. 10.1113/jphysiol.2009.170407
2009 Lumbers, E., Kim, M., Burrell, J., Kumarasamy, V., Boyce, A., Gibson, K. ... Owens, J. (2009). Effects of intrafetal IGF-I on growth of cardiac myocytes in late-gestation fetal sheep. American Journal of Physiology-Endocrinology and Metabolism, 296, 3, E513-E519. 10.1152/ajpendo.90497.2008
2009 Romano, T., Wark, J., Owens, J. & Wlodek, M. (2009). Prenatal growth restriction and postnatal growth restriction followed by accelerated growth independently program reduced bone growth and strength. Bone, 45, 1, 132-141. 10.1016/j.bone.2009.03.661
2009 Gatford, K., De Blasio, M., Roberts, C., Nottle, M., Kind, K., Van Wettere, W. ... Owens, J. (2009). Responses to maternal GH or ractopamine during early-mid pregnancy are similar in primiparous and multiparous pregnant pigs. Journal of Endocrinology, 203, 1, 143-154. 10.1677/JOE-09-0131
2008 Wadley, G., Siebel, A., Cooney, G., McConell, G., Wlodek, M. & Owens, J. (2008). Uteroplacental insufficiency and reducing litter size alters skeletal muscle mitochondrial biogenesis in a sex-specific manner in the adult rat. American Journal of Physiology-Endocrinology and Metabolism, 294, 5, E861-E869. 10.1152/ajpendo.00037.2008
2008 Gatford, K., Mohammad, S., Harland, M., De Blasio, M., Fowden, A., Robinson, J. & Owens, J. (2008). Impaired β-cell function and inadequate compensatory increases in β-cell mass after intrauterine growth restriction in sheep. Endocrinology, 149, 10, 5118-5127. 10.1210/en.2008-0233
2008 Siebel, A., Mibus, A., De Blasio, M., Westcott, K., Morris, M., Prior, L. ... Wlodek, M. (2008). Improved lactational nutrition and postnatal growth ameliorates impairment of glucose tolerance by uteroplacental insufficiency in male rat offspring. Endocrinology, 149, 6, 3067-3076. 10.1210/en.2008-0128
2008 Gatford, K., Owens, J., Li, S., Moss, T., Newnham, J., Challis, R. & Sloboda, D. (2008). Repeated betamethasone treatment of pregnant sheep programs persistent reductions in circulating IGF-I and IGF-binding proteins in progeny. American Journal of Physiology-Endocrinology and Metabolism, 295, 1, E170-E178. 10.1152/ajpendo.00047.2008
2008 Quigley, S., Kleemann, D., Walker, S., Speck, P., Rudiger, S., Nattrass, G. ... Owens, J. (2008). Effect of variable long-term maternal feed allowance on the development of the ovine placenta and fetus. Placenta, 29, 6, 539-548. 10.1016/j.placenta.2008.02.014
2008 Roberts, C., Owens, J. & Sferruzzi-Perri, A. (2008). Distinct Actions of Insulin-Like Growth Factors (IGFs) on Placental Development and Fetal Growth: Lessons from Mice and Guinea Pigs.. Placenta, 29, Supplement 1, 42-47. 10.1016/j.placenta.2007.12.002
2008 Sferruzzi-Perri, A., Owens, J., Standen, P. & Roberts, C. (2008). Maternal insulin-like growth factor-II promotes placental functional development via the type 2 IGF receptor in the guinea pig. Placenta, 29, 4, 347-355. 10.1016/j.placenta.2008.01.009
2008 Wlodek, M., Westcott, K., Siebel, A., Owens, J. & Moritz, K. (2008). Growth restriction before or after birth reduces nephron number and increases blood pressure in male rats. Kidney International, 74, 2, 187-195. 10.1038/ki.2008.153
2007 Morley, R., Moore, V., Dwyer, T., Owens, J., Umstad, M. & Carlin, J. (2007). Maternal birthweight and outcome of twin pregnancy. Paediatric and Perinatal Epidemiology, 21, 6, 501-506. 10.1111/j.1365-3016.2007.00848.x
2007 Owens, J., Gatford, K., De Blasio, M., Edwards, L., McMillen, I. & Fowden, A. (2007). Restriction of placental growth in sheep impairs insulin secretion but not sensitivity before birth. Journal of Physiology-London, 584, 3, 935-949. 10.1113/jphysiol.2007.142141
2007 De Blasio, M., Gatford, K., McMillen, I., Robinson, J. & Owens, J. (2007). Placental restriction of fetal growth increases insulin action growth and adiposity in the young lamb. Endocrinology, 148, 3, 1350-1358. 10.1210/en.2006-0653
2007 Pirc, L., Owens, J., Crowther, C., Willson, K., De Blasio, M. & Robinson, J. (2007). Mild gestational diabetes in pregnancy and the adipoinsular axis in babies born to mothers in the ACHOIS randomised controlled trial. BMC Pediatrics, 7, 18, 1-7. 10.1186/1471-2431-7-18
2007 Owens, J., Thavaneswaran, P., De Blasio, M., McMillen, I., Robinson, J. & Gatford, K. (2007). Sex-specific effects of placental restriction on components of the metabolic syndrome in young adult sheep. American Journal of Physiology-Endocrinology and Metabolism, 292, 6, E1879-E1889. 10.1152/ajpendo.00706.2006
2007 De Blasio, M., Dodic, M., Jefferies, A., Moritz, K., Wintour, E. & Owens, J. (2007). Maternal exposure to dexamethasone or cortisol in early pregnancy differentially alters insulin secretion and glucose homeostasis in adult male sheep offspring. American Journal of Physiology-Endocrinology and Metabolism, 293, 1, E75-E82. 10.1152/ajpendo.00689.2006
2007 Boyce, A., Gibson, K., Wintour, E., Koukoulas, I., Gatford, K., Owens, J. & Lumbers, E. (2007). The kidney is resistant to chronic hypoglycaemia in late-gestation fetal sheep. Canadian Journal of Physiology and Pharmacology, 85, 6, 597-605. 10.1139/Y07-047
2007 Gatford, K., Dalitz, P., Cock, M., Harding, P. & Owens, J. (2007). Acute ethanol exposure in pregnancy alters the insulin-like growth factor axis of fetal and maternal sheep. American Journal of Physiology-Endocrinology and Metabolism, 292, 2, 494-500. 10.1152/ajpendo.00269.2006
2007 De Blasio, M., Gatford, K., Robinson, J. & Owens, J. (2007). Placental restriction of fetal growth reduces size at birth and alters postnatal growth, feeding activity and adiposity in the young lamb. American Journal of Physiology-Regulatory Integrative and Comparative Physiology, 292, 2, 875-886. 10.1152/ajpregu.00430.2006
2007 Sferruzzi-Perri, A., Owens, J., Standen, P., Taylor, R., Heinemann, G., Robinson, J. & Roberts, C. (2007). Early treatment of the pregnant guinea pig with IGFs promotes placental transport and nutrient partitioning near term. American Journal of Physiology-Endocrinology and Metabolism, 292, 3, E668-E676. 10.1152/ajpendo.00320.2006
2007 Sferruzzi-Perri, A., Owens, J., Standen, P., Taylor, R., Robinson, J. & Roberts, C. (2007). Early pregnancy maternal endocrine insulin-like growth factor I programs the placenta for increased functional capacity throughout gestation. Endocrinology, 148, 9, 4362-4370. 10.1210/en.2007-0411
2007 Ross, J., McMillen, I., Lok, F., Thiel, A., Owens, J. & Coulter, C. (2007). Intrafetal insulin-like growth factor-I infusion stimulates adrenal growth but not steroidogenesis in the sheep fetus during late gestation. Endocrinology, 148, 11, 5424-5432. 10.1210/en.2006-1573
2007 Wlodek, M., Mibus, A., Tan, A., Siebel, A., Owens, J. & Moritz, K. (2007). Normal lactational environment restores nephron endowment and prevents hypertension after placental restriction in the rat. Journal of the American Society of Nephrology, 18, 6, 1688-1696. 10.1681/ASN.2007010015
2007 Kennaway, D., Owens, J., Voultsios, A., Boden, M. & Varcoe, T. (2007). Metabolic homeostasis in mice with disrupted Clock gene expression in peripheral tissues. American Journal of Physiology-Regulatory Integrative and Comparative Physiology, 293, 4, R1528-R1537. 10.1152/ajpregu.00018.2007
2006 Wintour, E. & Owens, J. (2006). Advances in Experimental Medicine and Biology: Preface. Advances in Experimental Medicine and Biology, 573, -.
2006 Morley, R., Umstad, M., Bond, J., Moore, V., Owens, J., Dwyer, T. & Carlin, J. (2006). Maternal dietary intake in twin pregnancies: Does it diminish towards term?. Twin Research and Human Genetics, 9, 5, 656-658. 10.1375/twin.9.5.656
2006 Sferruzzi-Perri, A., Owens, J., Pringle, K., Robinson, J. & Roberts, C. (2006). Maternal insulin-like growth factors-I and -II act via different pathways to promote fetal growth. Endocrinology, 147, 7, 3344-3355. 10.1210/en.2005-1328
2006 Kennaway, D., Owens, J., Voultsios, A. & Varcoe, T. (2006). Functional central rhythmicity and light entrainment, but not liver and muscle rhythmicity, are Clock independent. American Journal of Physiology-Regulatory Integrative and Comparative Physiology, 291, 4, R1172-R1180. 10.1152/ajpregu.00223.2006
2006 De Blasio, M., Gatford, K., Robinson, J. & Owens, J. (2006). Placental restriction alters circulating thyroid hormone in the young lamb postnatally. American Journal of Physiology-Regulatory Integrative and Comparative Physiology, 291, 4, R1016-R1024. 10.1152/ajpregu.00103.2006
2006 Lipsett, J., Tamblyn, M., Madigan, K., Roberts, P., Cool, J., Runciman, S. ... Owens, J. (2006). Restricted fetal growth and lung development: A morphometric analysis of pulmonary structure. Pediatric Pulmonology, 41, 12, 1138-1145. 10.1002/ppul.20480
2006 Walker, F., Owens, J., Ali, S. & Hodgson, D. (2006). Individual differences in glucose homeostasis: Do our early life interactions with bacteria matter?. Brain Behavior and Immunity, 20, 4, 401-409. 10.1016/j.bbi.2005.11.004
2005 Quigley, S., Kleemann, D., Kakar, M., Owens, J., Nattrass, G., Maddocks, S. & Walker, S. (2005). Myogenesis in sheep is altered by maternal feed intake during the peri-conception period. Animal Reproduction Science, 87, 3-4, 241-251. 10.1016/j.anireprosci.2004.11.005
2005 Grant, P., Kind, K., Roberts, C., Sohlstrom, A., Owens, P. & Owens, J. (2005). Late pregnancy increases hepatic expression of insulin-like growth factor-I in well nourished guinea pigs. Growth Hormone & IGF Research, 15, 2, 165-171. 10.1016/j.ghir.2005.01.002
2005 Morley, R., Moore, V., Dwyer, T., Owens, J., Umstad, M. & Carlin, J. (2005). Association between erythropoietin in cord blood of twins and size at birth: does it relate to gestational factors or to factors during labor or delivery?. Pediatric Research, 57, 5, 680-684. 10.1203/01.PDR.0000156505.12614.FF
2005 Sferruzzi-Perrio, A., Owens, J., Pringle, K., Robinson, J. & Roberts, C. (2005). Exogenous insulin like growth factors in early pregnancy act via different mechanisms to promote fetal growth. PLACENTA, 26, 8-9, A20-A20.
2005 Kind, K., Roberts, C., Sohlstrom, A., Katsman, A., Clifton, P., Robinson, J. & Owens, J. (2005). Chronic maternal feed restriction impairs growth but increases adiposity of the fetal guinea pig. American Journal of Physiology-Regulatory Integrative and Comparative Physiology, 288, 1, R119-R126. 10.1152/ajpregu.00360.2004
2004 Belobrajdic, D., McIntosh, G. & Owens, J. (2004). A high-whey-protein diet reduces body weight gain and alters insulin sensitivity relative to red meat in Wistar rats. Journal of Nutrition, 134, 6, 1454-1458.
2004 Gatford, K., De Blasio, M., Thavaneswaran, P., Robinson, J., McMillen, I. & Owens, J. (2004). Postnatal ontogeny of glucose homeostasis and insulin action in sheep. American Journal of Physiology-Endocrinology and Metabolism, 286, 6, E1050-E1059. 10.1152/ajpendo.00340.2003
2004 Briscoe, T., Rehn, A., Dieni, S., Duncan, J., Wlodek, M., Owens, J. & Rees, S. (2004). Cardiovascular and renal disease in the adolescent guinea pig after chronic placental insufficiency. American Journal of Obstetrics and Gynecology, 191, 3, 847-855. 10.1016/j.ajog.2004.01.050
2003 Roberts, C., Owens, J., Carter, A., Harding, J., Austgulen, R. & Wlodek, M. (2003). Insulin-like growth factors and foetal programming - a workshop report. Placenta, 24, 17, S72-S75. 10.1053/plac.2002.0935
2003 Belobrajdic, D., McIntosh, G. & Owens, J. (2003). Whey proteins protect more than red meat against azoxymethane induced ACF in Wistar rats. Cancer Letters, 198, 1, 43-51. 10.1016/S0304-3835(03)00307-0
2003 Kind, K., Clifton, P., Grant, P., Owens, P., Sohlstrom, A., Roberts, C. ... Owens, J. (2003). Effect of maternal feed restriction during pregnancy on glucose tolerance in the adult guinea pig. American Journal of Physiology-Regulatory Integrative and Comparative Physiology, 284, 1, R140-R152. 10.1152/ajpregu.00587.2001
2003 Gatford, K., Ekert, J., Blackmore, K., De Blasio, M., Boyce, J., Owens, J. ... Owens, P. (2003). Variable maternal nutrition and growth hormone treatment in the second quarter of pregnancy in pigs alter semitendinosus muscle in adolescent progeny. British Journal of Nutrition, 90, 2, 283-293. 10.1079/BJN2003893
2002 Kind, K., Simonetta, G., Clifton, P., Robinson, J. & Owens, J. (2002). Effect of maternal feed restriction on blood pressure in the adult guinea pig. Experimental Physiology, 87, 4, 469-477. 10.1111/j.1469-445x.2002.tb00060.x
2002 Oehlers, A., Owens, J., Redei, E. & Schwartz, J. (2002). Effect of maternal binge alcohol ingestion on fetal cardiovascular programming. FASEB JOURNAL, 16, 4, A102-A102.
2002 Coulter, C., Ross, J., Owens, J., Bennett, H. & McMillen, I. (2002). Role of pituitary POMC-peptides and insulin-like growth factor II in the developmental biology of the adrenal gland. Archives of Physiology and Biochemistry, 110, 1-2, 99-105. 10.1076/apab.110.1.99.894
2002 Morley, R., Owens, J., Blair, E. & Dwyer, T. (2002). Is birthweight a good marker for gestational exposures that increase the risk of adult disease?. Paediatric and Perinatal Epidemiology, 16, 3, 194-199. 10.1046/j.1365-3016.2002.00428.x
2002 Roberts, C., Kind, K., Earl, R., Grant, P., Robinson, J., Sohlstrom, A. ... Owens, J. (2002). Circulating insulin-like growth factor (IGF)-1 and IGF binding proteins -1 and -3 and placental development in the guinea-pig. Placenta, 23, 10, 763-770. 10.1053/plac.2002.0849
2002 Gatford, K., Clarke, I., De Blasio, M., McMillen, I., Robinson, J. & Owens, J. (2002). Perinatal growth and plasma GH profiles in adolescent and adult sheep. Journal of Endocrinology, 173, 1, 151-159. 10.1677/joe.0.1730151
2001 McMillen, I., Adams, M., Ross, J., Coulter, C., Simonetta, G., Owens, J. ... Edwards, L. (2001). Fetal growth restriction: adaptations and consequences. Reproduction, 122, 2, 195-204. 10.1530/rep.0.1220195
2001 Sohlstrom, A., Fernberg, P., Owens, J. & Owens, P. (2001). Maternal nutrition affects the ability of treatment with IGF-I and IGF-II to increase growth of the placenta and fetus, in guinea pigs. Growth Hormone & IGF Research, 11, 6, 392-398. 10.1054/ghir.2001.0253
2001 Phillips, I., Anthony, R., Simonetta, G., Owens, J., Robinson, J. & McMillen, I. (2001). Restriction of fetal growth has a differential impact on fetal prolactin and prolactin receptor mRNA expression. Journal of Neuroendocrinology, 13, 2, 175-181. 10.1046/j.1365-2826.2001.00608.x
2001 Marsh, A., Gibson, K., Wu, J., Owens, P., Owens, J. & Lumbers, E. (2001). Insulin-like growth factor I alters renal function and stimulates renin secretion in late gestation fetal sheep. Journal of Physiology-London, 530, 2, 253-262. 10.1111/j.1469-7793.2001.0253l.x
2001 Wilson, A., Martin, A., Lipsett, J., Parsonsc McMillen, D., Owens, J. & Kennedy, J. (2001). The effect of intrauterine growth restriction on postnatal lung function: The fetal origins of postnatal lung disease. Respirology, 6, SUPPL. 1, -.
2001 Roberts, C., Sohlstrom, A., Kind, K., Earl, R., Khong, T., Robinson, J. ... Owens, J. (2001). Maternal food restriction reduces the exchange surface area and increases the barrier thickness of the placenta in the guinea-pig. Placenta, 22, 02-Mar, 177-185. 10.1053/plac.2000.0602
2001 Robinson, J., McMillen, I., Edwards, L., Kind, K., Gatford, K. & Owens, J. (2001). Maternal and placental influences that program the fetus - Experimental findings. Lung Biology in Health and Disease, 151, 273-295.
2001 Kleemann, D., Walker, S., Hartwich, K., Fong, L., Seamark, R., Robinson, J. & Owens, J. (2001). Fetoplacental growth in sheep administered progesterone during the first three days of pregnancy. Placenta, 22, 1, 14-23. 10.1053/plac.2000.0594
2001 Marsh, A., Gibson, K., Wu, J., Owens, P., Owens, J. & Lumbers, E. (2001). Chronic effect of insulin-like growth factor I on renin synthesis, secretion, and renal function in fetal sheep. American Journal of Physiology-Regulatory Integrative and Comparative Physiology, 281, 1, R318-R326.
2001 McMillen, I., Owens, J., Coulter, C. & Robinson, J. (2001). Introduction: Moving on from controversies to mechanisms. Clinical and Experimental Pharmacology and Physiology, 28, 11, 930-930. 10.1046/j.1440-1681.2001.03551.x
2001 Edwards, L., Symonds, M., Warnes, K., Owens, J., Butler, T., Jurisevic, A. & McMillen, I. (2001). Responses of the fetal pituitary-adrenal axis to acute and chronic hypoglycemia during late gestation in the sheep. Endocrinology, 142, 5, 1778-1785. 10.1210/en.142.5.1778
2001 Roberts, C., Sohlstrom, A., Kind, K., Grant, P., Earl, R., Robinson, J. ... Owens, J. (2001). Altered placental structure induced by maternal food restriction in guinea pigs: A role for circulating IGF-II and IGFBP-2 in the mother?. Placenta, 22, Suppl A, S77-S82. 10.1053/plac.2001.0643
2000 Zhang, D., Lumbers, E., Simonetta, G., Wu, J., Owens, J., Robinson, J. & McMillen, I. (2000). Effects of placental insufficiency on the ovine fetal renin-angiotensin system. Experimental Physiology, 85, 1, 79-84. 10.1111/j.1469-445X.2000.01939.x
2000 Gatford, K., Wintour, E., De Blasio, M., Owens, J. & Dodic, M. (2000). Differential timing for programming of glucose homoeostasis, sensitivity to insulin and blood pressure by in utero exposure to dexamethasone in sheep. Clinical Science, 98, 5, 553-560. 10.1042/CS19990229
2000 Robinson, J., Moore, V., Owens, J. & McMillen, I. (2000). Origins of fetal growth restriction. European Journal of Obstetrics Gynecology and Reproductive Biology, 92, 1, 13-19. 10.1016/S0301-2115(00)00421-8
2000 Ross, J., Phillips, I., Simonetta, G., Owens, J., Robinson, J. & McMillen, I. (2000). Differential effects of placental restriction on IDF-II, ACTH receptor and steroidogenic enzyme mRNA levels in the foetal sheep adrenal. Journal of Neuroendocrinology, 12, 1, 79-85. 10.1046/j.1365-2826.2000.00429.x
2000 Gatford, K., Owens, J., Campbell, R., Boyce, J., Grant, P., De Blasio, M. & Owens, P. (2000). Treatment of underfed pigs with GH throughout the second quarter of pregnancy increases fetal growth. Journal of Endocrinology, 166, 1, 227-234. 10.1677/joe.0.1660227
2000 McMillen, I., Warnes, K., Adams, M., Robinson, J., Owens, J. & Coulter, C. (2000). Impact of Restriction of Placental and Fetal Growth on Expression of 11β-Hydroxysteroid Dehydrogenase Type 1 and Type 2 Messenger Ribonucleic Acid in the Liver, Kidney, and Adrenal of the Sheep Fetus1.. Endocrinology, 141, 2, 539-543. 10.1210/endo.141.2.7338
2000 McMillen, I., Warnes, K., Adams, M., Robinson, J., Owens, J. & Coulter, C. (2000). Impact of restriction of placental and fetal growth on expression of 11b-hydroxysteroid dehydrogenase type 1 and type 2 messenger ribonucleic acid in the liver, kidney, and adrenal of the sheep fetus. Endocrinology, 141, 2, 539-543. 10.1210/en.141.2.539
1999 Perry, V., Norman, S., Owens, J., Daniel, R. & Phillips, N. (1999). Low dietary protein during early pregnancy alters bovine placental development. Animal Reproduction Science, 55, 1, 13-21. 10.1016/S0378-4320(98)00157-2
1999 Kind, K., Clifton, P., Katsman, A., Tsiounis, M., Robinson, J. & Owens, J. (1999). Restricted fetal growth and the response to dietary cholesterol in the guinea pig. American Journal of Physiology - Regulatory Integrative and Comparative Physiology, 277, 6 46-6, R1675-R1682.
1999 Edwards, L., Simonetta, G., Owens, J., Robinson, J. & McMillen, I. (1999). Restriction of placental and fetal growth in sheep alters fetal blood pressure responses to angiotension II and captopril. Journal of Physiology (London), 515, 3, 897-904. 10.1111/j.1469-7793.1999.897ab.x
1998 Sohlstrom, A., Katsman, A., Kind, K., Roberts, C., Owens, P., Robinson, J. & Owens, J. (1998). Food restriction alters pregnancy-associated changes in IGF and IGFBP in the guinea pig. American Journal of Physiology, Endocrinology and Metabolism, 274, 37, E410-E416.
1998 Symonds, M., Phillips, I., Anthony, R., Owens, J. & McMillen, I. (1998). Prolactin receptor gene expression and foetal adipose tissue. Journal of Neuroendocrinology, 10, 11, 885-890. 10.1046/j.1365-2826.1998.00275.x
1998 Sohlstrom, A., Katsman, A., Kind, K., Grant, P., Owens, P., Robinson, J. & Owens, J. (1998). Effects of acute and chronic food restriction on the insulin-like growth factor axis in the guinea pig. Journal of Endocrinology, 157, 1, 107-114. 10.1677/joe.0.1570107
1998 Coulter, C., McMillen, I., Robinson, J. & Owens, J. (1998). Placental Restriction Alters Adrenal Medullary Development in the Midgestation Sheep Fetus. Pediatric Research, 44, 5, 656-662. 10.1203/00006450-199811000-00007
1998 Warnes, K., Morris, M., Symonds, M., Phillips, I., Owens, J. & McMillen, I. (1998). Effects of increasing gestation, cortisol and maternal undernutrition on hypothalamic neuropeptide Y expression in the sheep fetus. Journal of Neuroendocrinology, 10, 1, 51-57. 10.1046/j.1365-2826.1998.00172.x
1997 Simonetta, G., Rourke, A., Owens, J., Robinson, J. & McMillen, I. (1997). Impact of placental restriction on the development of the sympathoadrenal system. Pediatric Research, 42, 6, 805-811. 10.1203/00006450-199712000-00015
1997 Ross, J., Phillips, I., Owens, J. & McMillen, I. (1997). Cortisol differentially regulates pituitary-adrenal function in the sheep fetus after disconnection of the hypothalamus and pituitary. Journal of Neuroendocrinology, 9, 9, 663-668. 10.1046/j.1365-2826.1997.00623.x
1997 Trahair, J., De Barro, T., Robinson, J. & Owens, J. (1997). Restriction of Nutrition In Utero Selectively Inhibits Gastrointestinal Growth in Fetal Sheep. Journal of Nutrition, 127, 4, 637-641.
1997 Robinson, J., Owens, J. & McMillen, I. (1997). Back to the womb. Today's Life Sciences, 9, 18-25.
1997 Robinson, J., Hartwich, K., Walker, S., Erwich, J. & Owens, J. (1997). Early influences on embryonic and placental growth. Acta Paediatrica Supplement, 86, S423, 159-163. 10.1111/j.1651-2227.1997.tb18401.x
1997 Farmer, E., Trahair, J., Lok, F. & Owens, J. (1997). Vascular infusion of insulin-like growth factor I (IGF-I) does not stimulate fetal gut growth.. GASTROENTEROLOGY, 112, 4, A874-A874.
1997 Symonds, M., Heasman, L., Clarke, L., Firth, K., Owens, J. & McMillen, I. (1997). Maternal nutrition in late gestation and placental growth. Contemporary Reviews in Obstetrics and Gynaecology, 9, 3, 165-172.
1997 Trahair, J., Wing, S., DeBarro, T. & Owens, J. (1997). Gastrointestinal growth of fetal sheep is an early target for the effects of intrauterine growth retardation. Journal of Nutrition, 127, 637-641.
1996 Phillips, I., Ross, J., Owens, J., Young, I. & McMillen, I. (1996). The peptide ACTH (1-39), adrenal growth and steroidogenesis in the sheep fetus after disconnection of the hypothalamus and pituitary. Journal of Physiology, 491, 3, 871-879. 10.1113/jphysiol.1996.sp021264
1996 Phillips, I., Ross, J., Owens, J., Young, I. & McMillen, I. (1996). Circulating proopiomelanocortin-derived peptide concentrations and adrenal insulin-like growth factor-II and steroidogenic enzyme mRNA levels in fetal sheep during late gestation and after disconnection of the fetal hypothalamus and pituitary. Journal of Physiology, 491, 871-879.
1996 Phillips, I., Simonetta, G., Owens, J., Robinson, J., Clarke, I. & McMillen, I. (1996). Placental restriction alters the functional development of the pituitary-adrenal axis in the sheep fetus during late gestation. Pediatric Research, 40, 6, 861-866. 10.1203/00006450-199612000-00014
1996 Lok, F., Owens, J., Mundy, L., Robinson, J. & Owens, P. (1996). Insulin-like growth factor-I promotes growth selectively in fetal sheep in late gestation. American Journal of Physiology. Regulatory Integrative and Comparative Physiology, 270, 5, R1148-R1155.
1996 Phillips, I., Simonetta, G., Owens, J., Robinson, J., Clarke, I. & McMillen, I. (1996). The relative roles of the hypothalamus and cortisol in the control of prolactin gene expression in the anterior pituitary of the sheep fetus. Journal of Neuroendocrinology, 8, 12, 929-933. 10.1111/j.1365-2826.1996.tb00823.x
1996 Ogawa, E., Breier, B., Bauer, M., Gallaher, B., Grant, P., Walton, P. ... Gluckman, P. (1996). Pretreatment with bovine growth hormone is as effective as treatment during metabolic stress to reduce catabolism in fasted lambs. Endocrinology, 137, 4, 1242-1248. 10.1210/en.137.4.1242
1996 Li, J., Owens, J., Owens, P., Saunders, J., Fowden, A. & Gilmour, R. (1996). The ontogeny of hepatic growth hormone receptor and insulin-like growth factor I gene expression in the sheep fetus during late gestation: developmental regulation by cortisol. Endocrinology, 137, 5, 1650-1657. 10.1210/en.137.5.1650
1996 Kind, K., Owens, J., Lok, F., Robinson, J., Quinn, K., Mundy, L. ... Owens, P. (1996). Intravenous infusion of insulin-like growth factor I in fetal sheep reduces hepatic IGF-I and IGF-II mRNAs. American Journal of Physiology. Regulatory Integrative and Comparative Physiology, 271, 6, R1632-R1637.
1996 Fowden, A., Owens, J., Owens, P. & Gilmour, R. (1996). The ontogeny of hepatic 6H receptor and IGF-1 gene expression in the sheep fetus during late gestation: developmental regulation by cortisol. Endocrinology, 137, 1650-1657.
1995 Beanland, C., Browne, C., Young, R., Owens, J., Walton, P. & Thorburn, G. (1995). Fetal plasma insulin-like growth factor binding protein-3 concentrations are elevated following bilateral nephrectomy in fetal sheep. Reproduction, Fertility and Development, 7, 3, 345-349. 10.1071/RD9950345
1995 Kind, K., Owens, J., Robinson, J., Quinn, K., Grant, P., Walton, P. ... Owens, P. (1995). Effect of restriction of placental growth on expression of IGFs in fetal sheep: Relationship to fetal growth, circulating IGFs and binding proteins. Journal of Endocrinology, 146, 1, 23-34. 10.1677/joe.0.1460023
1995 Carr, J., Owens, J., Baudinette, R. & Wallace, J. (1995). Analysis of insulin-like growth factor binding proteins (IGFBPs) in the Tammar wallaby. General and Comparative Endocrinology, 99, 50-59.
1995 Kind, K., Owens, J., Robinson, J., Quinn, K., Grant, P., Walton, P. ... Owens, P. (1995). Effect of restriction of placental growth on expression of insulin-like growth factors-I and -II in fetal sheep: relationship to growth, circulating insulin-like growth factors and metabolites. Journal of Endocrinology, 146, 23-34.
1995 Robinson, J., Chidzanja, S., Kind, K., Owens, P. & Owens, J. (1995). Placental control of fetal growth. Reproduction, Fertility and Development, 7, 3, 333-344. 10.1071/RD9950333
1995 Carr, J., Owens, J., Baudinette, R. & Wallace, J. (1995). Analysis of insulin-like growth factor binding proteins in the tammar wallaby, Macropus eugenii. General and Comparative Endocrinology, 99, 1, 50-59. 10.1006/gcen.1995.1084
1995 Carr, J., Owens, J., Grant, P., Walton, P., Owens, P. & Wallace, J. (1995). Circulating insulin-like growth factors (IGFs), IGF-binding proteins (IGFBPs) and tissue mRNA levels of IGFBP-2 and IGFBP-4 in the ovine fetus. Journal of Endocrinology, 145, 3, 545-557. 10.1677/joe.0.1450545
1995 McMillen, I., Phillips, I., Ross, J., Robinson, J. & Owens, J. (1995). Chronic stress - the key to parturition?. Reproduction, Fertility and Development, 7, 3, 499-507. 10.1071/RD9950499
1995 Carr, J., Owens, J., Baudinette, R. & Wallace, J. (1995). Characterisation of insulin-like growth factor binding proteins (IGFBPs) in the tammar wallaby (Macropus eugenii). Journal of General and Comparative Endocrinology, 99, 50-59.
1994 CARR, J., GRANT, P., FRANCIS, G., OWENS, J., WALLACE, J. & WALTON, P. (1994). Isolation and characterization of ovine IGFBP-4: protein purification and cDNA sequence. Journal of Molecular Endocrinology, 13, 2, 219-236. 10.1677/jme.0.0130219
1994 Owens, J., Kind, K., Carbone, F., Robinson, J. & Owens, P. (1994). Circulating insulin-like growth factors-I and -II and substrates in fetal sheep following restriction of placental growth. Journal of Endocrinology, 140, 1, 5-13. 10.1677/joe.0.1400005
1994 Robinson, J., Seamark, R. & Owens, J. (1994). Placental Function. Australian and New Zealand Journal of Obstetrics and Gynaecology, 34, 3, 240-246. 10.1111/j.1479-828X.1994.tb01065.x
1993 Barker, D., Godfrey, K., Gluckman, P., Harding, J., Owens, J. & Robinson, J. (1993). Fetal nutrition and cardiovascular disease in adult life. The Lancet, 341, 8850, 938-941. 10.1016/0140-6736(93)91224-A
1992 Harding, J., Owens, J. & Robinson, J. (1992). Should we try to supplement the growth retarded fetus? A cautionary tale. BJOG: An International Journal of Obstetrics & Gynaecology, 99, 9, 707-710. 10.1111/j.1471-0528.1992.tb13866.x
1991 Gargosky, S., Owens, P., Walton, P., Owens, J., Robinson, J., Wallace, J. & Ballard, F. (1991). Most of the circulating insulin-like growth factors-I and -II are present in the 150 kDa complex during human pregnancy. Journal of Endocrinology, 131, 3, 491-497. 10.1677/joe.0.1310491
1991 Owens, J. (1991). Endocrine and substrate control of fetal growth: Placental and maternal influences and insulin-like growth factors. Reproduction, Fertility and Development, 3, 5, 501-517. 10.1071/RD9910501
1991 Gargosky, S., Owens, J., Walton, P., Owens, P., Wallace, J. & Ballard, F. (1991). Administration of insulin-like growth factor-I, but not growth hormone, increases maternal weight gain in late pregnancy without affecting fetal or placental growth. Journal of Endocrinology, 130, 3, 395-400. 10.1677/joe.0.1300395
1990 Gargosky, S., Moyse, K., Walton, P., Owens, J., Wallace, J., Robinson, J. & Owens, P. (1990). Circulating levels of insulin-like growth factors increase and molecular forms of their serum binding proteins change with human pregnancy. Biochemical and Biophysical Research Communications, 170, 3, 1157-1163. 10.1016/0006-291X(90)90514-N
1989 Smeaton, T., Owens, J. & Robinson, J. (1989). Micro-method for measurement of branched-chain keto acid concentrations in plasma from sheep and man. Journal of Chromatography B: Biomedical Sciences and Applications, 487, C, 434-439. 10.1016/S0378-4347(00)83051-0
1989 Owens, J., Falconer, J. & Robinson, J. (1989). Glucose metabolism in pregnant sheep when placental growth is restricted. American Journal of Physiology - Regulatory Integrative and Comparative Physiology, 257, 2, R350-R357.
1989 Owens, P., Owens, J., Lovelock, M., Chan, E., Falconer, J., Ribonson, J. & Smith, R. (1989). Restriction of placental growth in sheep enhances placental metabolism of fetal β-endorphin-like immunoreactivity. Journal of Developmental Physiology, 11, 2, 63-71.
1989 Smeaton, T., Owens, J., Kind, K. & Robinson, J. (1989). The placenta releases branched-chain keto acids into the umbilical and uterine circulations in the pregnant sheep. Journal of Developmental Physiology, 12, 2, 95-99.
1988 Jacobs, R., Robinson, J., Owens, J., Falconer, J. & Webster, M. (1988). The effect of prolonged hypobaric hypoxia on growth of fetal sheep. Journal of Developmental Physiology, 10, 2, 97-112.
1988 Jacobs, R., Owens, J., Falconer, J., Webster, M. & Robinson, J. (1988). Changes to metabolite concentration in fetal sheep subjected to prolonged hypobaric hypoxia. Journal of Developmental Physiology, 10, 2, 113-121.
1987 Owens, J., Falconer, J. & Robinson, J. (1987). Restriction of placental size in sheep enhances efficiency of placental transfer of antipyrine, 3-O-methyl-D-glucose but not of urea.. Journal of Developmental Physiology, 9, 5, 457-464.
1987 Owens, J., Falconer, J. & Robinson, J. (1987). Effect of restriction of placental growth on fetal and utero-placental metabolism. Journal of Developmental Physiology, 9, 3, 225-238.
1987 Owens, J., Falconer, J. & Robinson, J. (1987). Effect of restriction of placental growth on oxygen delivery to and consumption by the pregnant uterus and fetus. Journal of Developmental Physiology, 9, 2, 137-150.
1986 Owens, J. A., Falconer, J. & Robinson, J. S. (1986). Effect of restriction of placental growth on umbilical and uterine blood flows. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, 250, 3, R427-R434.
1985 Mack, U., Owens, J., Cooksley, W., Powell, L. & Halliday, J. (1985). The effect of acute liver damage on circulating ferritin levels in vivo and in the isolated perfused rat liver. British Journal of Experimental Pathology, 66, 2, 185-191.
1985 Falconer, J., Owens, J. A., Allotta, E. & Robinson, J. S. (1985). Effect of restriction of placental growth on the concentrations of insulin, glucose and placental-lactogen in the plasma of sheep. Journal of Endocrinology, 106, 1, 7-11. 10.1677/joe.0.1060007
1985 Robinson, J., Falconer, J. & Owens, J. (1985). Intrauterine growth retardation: Clinical and experimental. Acta Paediatrica Scandinavica, 74, SUPPL. 319, 135-142.
1985 OWENS, J. A. & ROBINSON, J. S. (1985). Isolation and quantitation of carbohydrates in sheep plasma by high-performance liquid chromatography. Journal of Chromatography B: Biomedical Sciences and Applications, 338, 2, 303-314. 10.1016/0378-4347(85)80101-8
1985 Owens, J. A., Scott, J. S. D. & Cooksley, W. G. E. (1985). The retention of cobalamin by the liver in the cobalamin-deficient rat. Clinical Science, 68, 5, 553-560. 10.1042/cs0680553
1984 Scott, J. S. D., Treston, A. M., Bowman, E. P. W., Owens, J. A. & Cooksley, W. G. E. (1984). The regulatory roles of liver and kidney in cobalamin (vitamin-B₁₂) metabolism in the rat: the uptake and intracellular binding of cobalamin and the activity of the cobalamin-dependent enzymes in response to varying cobalamin supply. Clinical Science, 67, 3, 299-306. 10.1042/cs0670299
1984 Owens, J. & Robinson, J. (1984). High-performance liquid-chromatographic determination of plasma lactate specific radioactivity. Journal of Chromatography B: Biomedical Sciences and Applications, 307, 2, 380-386. 10.1016/S0378-4347(00)84109-2
1981 Owens, J. & Cooksley, W. (1981). Intracellular binding of cobalamin by liver and kidney. Clinical and Experimental Pharmacology and Physiology, 8, 4, 366-367.
1980 Owen, J. & Nakatsu, K. (1980). Disposition of intravenous theophylline‐7‐acetic acid in rabbits. Biopharmaceutics & Drug Disposition, 1, 4, 179-186. 10.1002/bdd.2510010405
1980 Owens, J. & Cooksley, W. (1980). Dietary vitamin B12 deficiency-effect on hepatic metabolism of vitamin B12 and methyltetrahydrofolate. Clinical and Experimental Pharmacology and Physiology, 7, 1, 91-92.
1977 Cooksley, W. & Owens, J. (1977). The hepatic regulation of cobalamin in vitamin B12 deficiency. Gastroenterology, 73, 5, -.

Books

Year Citation
2006 E. Wintour & J. Owens (Eds.) (2006). Early Life Origins of Health and Disease. Advances in Experimental Medicine and Biology Vol 573. New York: Springer.

Book Chapters

Year Citation
2006 Owens, J., Gatford, K., De Blasio, M., Horton, D., Kind, K. & Robinson, J. (2006). Perinatal programming of metabolic homeostasis. In D. M. Hodgson & C. L. Coe (Eds.), Perinatal programming : early life determinants of adult health & disease (pp. 97-116). London: Taylor & Francis.
1999 Robinson, J., McMillen, I., Edwards, L., Erwich, J., Roberts, C., Kind, K. & Owens, J. (1999). The effect of maternal nutrition on growth and development before and after birth. In Fetal programming: Influences on development and disease in later life (pp. 217-230). RCOG Press.
1997 Owens, J., Kind, K. & Robinson, J. (1997). Oxygenation in utero: placental determinants and fetal requirements. In Placental function and fetal nutrition (pp. 123-141). Lippincott-Raven.
1997 Owens, P., Quinn, K., Knowles, S., Campbell, R., Kind, K., Owens, J. ... Shephard, R. (1997). Plasma insulin-like growth factors and binding proteins in growth retarded children with liver disease. In Third Proceedings of the DSL International Scientific Meeting (pp. 147-151). DSL Inc.
1996 Robinson, J. & Owens, J. (1996). Pathophysiology of intrauterine growth failure. In Pediatrics and Perinatology: The Scientific Basis (pp. 290-297). Arnold.
1995 Robinson, J. & Owens, J. (1995). Control of fetal growth. In Scientific essentials of reproductive medicine, 1995 (pp. 329-341). W.B. Saunders.
1995 Owens, J., Owens, P. & Robinson, J. (1995). Experimental restriction of fetal growth. In Growth, 1995 (pp. 139-175). Cambridge University Press.

Competitive Research Funding

International Competitive Schemes

Date Project/No. Investigators Funding Body Amount
2011-2012 Long-term effects of early nutrition on later health. FP7-289346-EarlyNutrition  Dodd J and Owens JA; 36 Partner Universities & Organisations EU Framework Research Program Project EU 11,000,000
2011-2012 Preventing paternal programming of obesity in offspring 

Lane M, Owens JA, Mitchell M

Bill & Melinda Gates Foundation

US
100,000

2008-2009

Metabolic programming: Impact of insulin and IGFs on blastocyst metabolism

Owens JA and Fischer B

Group of Eight/DAAD Australian-German
Research Co-operation Scheme
AUD
32,000

National Competitive Schemes

Date Project/No. Investigators Funding Body Amount
2015 Effects of Metformin Exposure during Pregnancy on the Epigenome Hardikar A, Nolan C, Hague B and Owens JA Diabetes Australia Research Trust             AUD
60,000
2012-2014

Causal pathways from maternal obesity to pregnancy, perinatal & childhood health outcomes/ Project ID 1068320

Dodd J, Owens JA and others 

National Health and Medical Research Council of Australia (NHMRC)

US
755,934

2012-2014

Diet and exercise intervention for paternal obesity improves offspring health/ Project ID 1022882

Lane M, Owens JA, Mitchell, M

National Health and Medical Research Council of Australia (NHMRC) AUD
656,100
2014-2015 Circadian rhythm disruption and metabolic function/ Project ID 1029869 Kennaway DJ, McConell G, Owens JA National Health and Medical Research Council of Australia (NHMRC) AUD
605,505
2012-2013

Can exercise prevent diabetes in adults who grew poorly before birth? Studies in an ovine model of IUGR.

Gatford, K, McConell G, Owens JA

Diabetes Australia Research Trust, Millennium 2 Award      AUD
145,000
2012-2013 Identifying epigenetic pathways from maternal obesity to type 2 diabetes in offspring     Owens JA, Dodd J, Relton C, Lawlor D, Poston L. Diabetes Australia Research Trust, Millennium 2 Award        AUD
145,000
2011-2013

Preventing insulin resistance and obesity following fetal growth restriction/ Project ID 1011767

Owens JA, DeBlasio M, Gatford KL, Hiendleder S National Health and Medical Research Council of Australia (NHMRC) AUD
891,732
2010-2012 Preventing early life programming of impaired insulin secretion and diabetes/ Project ID 627123 Gatford KL, Owens JA, Dziadek M, Simmons R and De Blasio MJ National Health and Medical Research Council of Australia (NHMRC) AUD
733,500
2010

Do maternal and infant obesity related genotypes influence efficacy of interventions to limit weight gain in obese pregnant women and obesity in their offspring?

Dodd JM, Owens JA, Robinson JS Clive and Vera Ramaciotti Foundation AUD
50,000
2010 Does periconceptional folic acid supplementation alter metabolic health of progeny? Owens JA Diabetes Australia Research Trust AUD
65,000
2010

Do maternal and infant obesity related genotypes influence efficacy of interventions to limit weight gain in obese pregnant women and obesity in their offspring?

Robinson JS, Dodd JM and Owens JA Channel 7 Children’s Research Foundation AUD
50,000
2009 Pregnancy and lactation interventions to increase progeny birthweight and growth and survival to weaning Gatford KL, Owens JA, Nottle M, Kind KL, van Wettere WH and De Blasio MJ  CRC for an Internationally Competitive Pork Industry            AUD
119,926
2007-2009

Functional and epigenetic consequences of maternal folate deficiency, supplementation and fetal growth restriction/ Project ID 453640

Owens JA, Dziadek M, Robinson JS National Health and Medical Research Council of Australia (NHMRC) AUD
525,000
2007-2009

Does women’s nutrition during pregnancy influence metabolic health in their children?/ Project ID 453655

Moore V, Owens JA, Phillips D and Robinson JS

National Health and Medical Research Council of Australia (NHMRC) AUD
242,138
2007-2009 Development of a selection marker for placental efficiency/ Project ID 2E-103 0506

Roberts C and Owens JA

CRC for an Internationally Competitive Pork Industry            AUD
480,000
2006-2008

The effects of dietary arginine during gestation on the subsequent litter size of gilts and sows/ Project ID 2E-102 0607

Owens JA, Roberts CT, Nottle MB  CRC for an Internationally Competitive Pork Industry            AUD
284,829
2006-2008

How does disruption of circadian rhythms induce diabetes?/ Project ID 399131

Kennaway DJ and Owens JA National Health and Medical Research Council of Australia (NHMRC) AUD
624,000
2006 Maternal calcium supplementation and prevention of diabetes in offspring born small

Owens JA, Wlodek ME, Robinson JS

Diabetes Australia Research Trust AUD
45,000
2006 Metabolic consequences of circadian rhythm disruption in an animal model of shiftwork

Kennaway DJ and Owens JA

Diabetes Australia Research Trust AUD
50,000
2005

Identification of genes involved in altered glucose metabolism and adiposity in the adult following perinatal growth restriction

Wlodek ME and Owens JA

Diabetes Australia Research Trust AUD
44,800
2004-2005

Placental and mammary programming of Syndrome X

Wlodek ME and Owens JA National Heart Foundation of Australia         AUD
100,000
2002-2006 Early Origins of Adult Disease NHMRC  Program Grant/ Project ID: 207728
 

Robinson, JS, McMillen IC, Owens JA, Owens PC, Coulter C and Schwartz, JS

National Health and Medical Research Council of Australia (NHMRC) AUD
4,600,000
2002-2006 Prenatal programming of adult insulin resistance (incorporated into NHMRC Program, 2002-2006)/ Project ID: 207728

Owens JA, Kind KL and Robinson JS

National Health and Medical Research Council of Australia (NHMRC) AUD
465,000
2002-2006

Prenatal programming of postnatal growth hormone secretion and sensitivity (incorporated into of NHMRC Program, 2002-2006)/ Project ID: 207728

Gatford KL, Schwartz, J and Owens JA

National Health and Medical Research Council of Australia (NHMRC) AUD
450,000
2003-2004

Placental and lactational programming of adult hypertension and insulin resistance

Owens JA & Wlodek ME Channel 7 Children’s Research Foundation AUD
76,000
2001-2003 Prolactin and fetal growth

McMillen IC, Owens JAand Waters MJ

Australian Research Council (ARC) AUD
180,000
2000-2002

Antenatal insulin-like growth factor-I and perinatal growth, survival and function of the growth restricted fetus (incorporated into NHMRC Program, 2002-2006)/ Project ID: 207728

Owens, JA and Robinson, JS National Health and Medical Research Council of Australia (NHMRC) AUD
76,000p.a
2000-2002

Gestational influences on outcomes in twins

Morley R, Dwyer T Moore V and Owens JA National Health and Medical Research Council of Australia (NHMRC) AUD
267,939
2000-2001 How does prenatal growth alter the cholesterol homeostatic response to dietary cholesterol and saturated fat in adult life? Owens JA, Kind KL and Clifton P National Heart Foundation of Australia AUD
81,000
1999-2001

How does placental restriction of fetal growth alter the somatotropic axis and growth regulation after birth?

Owens JA and Robinson JS National Health and Medical Research Council of Australia (NHMRC) AUD
378,000
1999-2000

Does cortisol induce increased blood pressure dependence on the renin-angiotensin system in growth restricted fetal lambs?

Robinson JS, Owens JA National Heart Foundation of Australia AUD
154,500
1999 Role of altered amino acid availability and utilisation in prenatal programming of later function/ Project RAMA 98079  Owens JA Clive and Vera Ramaciotti Foundations           AUD
10,000
1999

Are endogenous GH profiles or GH sensitivity altered during catch-up growth following IUGR?

Owens JA, Gatford KL, Owens PC

AZA Research Australia   AUD
10,000
1998-1999 Glucocorticoids, 11Bhydroxysteroid dehydrogenase and the fetal origins of adult disease McMillen IC, Coulter C, Robinson JS, Owens JA National Heart Foundation of Australia AUD
90,000
1997-1999

Insulin-like growth factors and fetal and placental growth

Owens JA, Robinson JS National Health and Medical Research Council (NHMRC) AUD
330,000
1997-1999

NPY and the control of ACTH secretion before birth

McMillen IC, Owens JA,Robinson JS National Health and Medical Research Council (NHMRC) AUD
174,000
1997-1998

Effects of early perturbed development on adult cholesterol homeostasis

Kind KL, Owens JA,Clifton P

National Heart Foundation of Australia AUD
105,000
1996-1998

Fetal growth restriction alters the regulation of blood pressure before and after birth

Robinson JS, McMillen IC,Owens JA

National Health and Medical Research Council (NHMRC) AUD
220,878
1996-1997 Nutrient partitioning during pregnancy Owens PC, Owens JA, Campbell R Pig Development Research Corporation      AUD
220,000
1996-1997 The vascular consequences of intrauterine growth retardation: the fetal origins of adult hypertension McMillen IC, Robinson JS, Owens JA, Roberts ML National Heart Foundation AUD
70,000
1995 Fetal origins of adult disease: Second International Study Group Robinson JS, McMillen IC, Owens JA, Lumbers EL, Gluckman PD Department of Industry, Technology and Regional Development AUD
21,120
1994-1995

Impact of intra-uterine growth retardation on development of the sympathetic nervous system

McMillen IC, Robinson JS, Roberts MC, Owens JA National Heart Foundation AUD
135,000
1991-1996

Insulin-like growth factors and fetal growth retardation

Owens JA, Robinson JS National Health and Medical Research Council (NHMRC) AUD
644,826
1989-1991

Altered protein turnover and accretion in the growth-retarded fetus

Owens JA, Robinson JS National Health and Medical Research Council (NHMRC) AUD
271,896
1989-1991

Metabolic and endocrine status of the “at-risk” fetus

Robinson JS, Owens JA Clive and Vera Ramaciotti Foundation

AUD
15,000

1987-1989 Ontogeny of amino-acid utilisation by the fetus and placenta Owens JA, Robinson JS National Health and Medical Research Council AUD
132,675
1987-1988 Ontogeny of protein turnover and accretion in the fetus and placenta Owens JA Queen Elizabeth II Research Fellowship     AUD
99,075

State Competitive and Intramural Schemes

Date Project/No. Investigators Funding Body Amount
2012

Dietary treatment of cardioinflammatory markers in pregnancy in overweight and obese women

Moran L, Dodd J, Grivell R and Owens J WCH Foundation AUD
90,000
2003-2004 Placental and lactational programming of adult hypertension and insulin resistance

Owens JA, Wlodek ME

Channel 7 Children’s Research Foundation

AUD
76,000

2002-2003

Amelioration of IUGR to reduce infant mortality and morbidity

Owens JA and Fischer B

Group of Eight/DAAD Australian-German
Research Co-operation Scheme
AUD
32,000
 
2001

Exposure of pregnant rats to alcohol as a model for studying fetal programming of high blood pressure and diabetes

Schwartz J, Owens JA

Adelaide University Small Grant Scheme AUD
10,000
2001 Role of growth hormone in neonatal growth

Gatford KL, Owens JA

Adelaide University Small Grant Scheme AUD
10,000
2001 Influence of dietary fats and heme on risk markers for colon cancer

Owens JA, G MacKintosh

Adelaide University Small Grant Scheme AUD
10,000
2001

Does fetal cortisol regulate placental functional development?

Owens JA University of Adelaide Grant         AUD
10,000
2000 How does restriction of fetal growth alter adult insulin sensitivity?

Owens JA

Faculty of Health Sciences B1 Grant AUD
10,000
1999-2000 Effect of antenatal IGF-I on perinatal growth, survival and function of the growth restricted fetal sheep Owens JA Channel 7 Children’s Research Foundation of SA     AUD
100,000
1999-2000

Effect of single and multiple dose antenatal steroids on lung development in the  intrauterine growth restricted fetal sheep

Lipsett J, Owens JA Channel 7 Children’s Research Foundation of SA     AUD
80,000
1997 Intrauterine growth restriction and lung disease: Fetal origins of adult disease

Lipsett J, Owens JA, Robinson JS, Runciman SC

WCH Foundation AUD
40,000
1996 Early determinants of postnatal outcomes

Owens JA, Owens, PC, Robinson, JS

Australian Research Council (ARC) AUD
14,600
1996

Restricted growth in utero alters the endocrine regulation of carbohydrate and lipid metabolism and of growth after birth

Owens JA

Division of Science, University of Adelaide Setup Grant AUD
25,000
1995 Role of the fetal hypothalamo-pituitary-adrenal axis in the cellular, functional and endocrine development of the placenta Phillips I, Owens JA, McMillen IC Australian Research Council Small Grant    AUD
16,000
1994 Prenatal programming of cardiovascular and metabolic systems: innovative research strategies

McMillen IC, Owens JA, Robinson JS

University of Adelaide Quality Audit Research Scheme AUD
45,000
1992-1993

Treatment of gut insufficiency in premature and low birthweight infants

Trahair J, Owens JA Channel 7 Children’s Res. Foundation of S.A. Inc. AUD
90,000
1992-1993

Does the placenta exchange insulin-like growth factors with the mother and the fetus?

Owens JA, Owens PC University of Adelaide Research Grant AUD
67,000
1991 Role of insulin-like growth factor-binding proteins in maternal adaptation to pregnancy

Robinson JS, Owens JA

Queen Victoria Hospital Research Foundation AUD
25,000
1990-1991

Insulin-like growth factor-I modulation of growth and function in the developing placenta

Owens JA, Robinson JS University of Adelaide Research Grant       AUD
60,000
1990 Measurement of insulin-like growth factor-binding proteins in tissues and blood of normal and growth-retarded fetal sheep Owens JA, Walton PE CSIRO
University of Adelaide Collab. Res. Fund   
AUD
7,000
1989 Epidermal growth factor treatment to improve placental growth and function Owens JA University of Adelaide Research Grant AUD
2,500
1989

Purification and assay of the insulin-like growth factor-binding proteins from ovine blood and amniotic fluid

Owens JA, Walton PE CSIRO
University of Adelaide Collab. Res. Fund 
AUD
7,000
1988

Protein turnover and accretion in the growth retarded fetus

Owens JA, Robinson JS University of Adelaide Research Grant AUD
4,000
1988

Role of insulin-like growth factors in the control of substrate delivery by the placenta to the fetus

Owens JA, Robinson JS, Ballard FJ, Owens PC CSIRO
University of Adelaide Collab. Res. Fund  
AUD
10,000
1987 Insulin and insulin-like growth factors in the fetus Owens JA, Robinson, JS, Owens, PC University of Adelaide Research Grant       AUD
4,000

National Competitive Infrastructure and Equipment Funding Schemes

Date Project/No. Investigators Funding Body Amount
2012

High throughput image analysis system for histoquantification of histology images

Tilley W, Owens JA and others National Health and Medical Research Council of Australia Equipment Grant AUD
60,000
2012 Metabolic, enzyme and selected hormone profiling Analyzer

Owens JA and others

National Health and Medical Research Council of Australia Equipment Grant

AUD
43,000

2011

PhenoMaster system for physiological and behavioural phenotyping of laboratory rodents

Kennaway DJ, Owens JA and others

National Health and Medical Research Council of Australia Equipment Grant AUD
26,000
2010 Cryogenic Facility

Dodd JM, Owens JA and others

National Health and Medical Research Council of Australia Equipment Grant AUD
33,000
2007

A  microarray platform for gene expression analysis and genotyping in biological systems

Tilley W, Owens JA and others

Australian Research Council LEIF 

AUD
196,000

2007 Corbett robotics model CAS-1200 liquid handling robot Owens JA and others National Health and Medical Research Council of Australia Equipment Grant AUD
10,000
2006 BioRad  BioPlex Suspension System

JA Owens, SA Robertson, DJ Kennaway, CT Roberts, M Davies, RJ Norman, KL Gatford K Kind, JS Robinson, PA Grant, A Somogyi, G Wittert, R Rodgers

National Health and Medical Research Council of Australia Equipment Grant AUD
50,000
2006

Automated image analysis system for the high throughput immunohistochemical analysis of clinical and experimental samples

WD Tilley, JA Owens, RJ Norman, D Findlay, FJ Rodgers, CT Roberts, G Wittert, C Ricciardellil, I Musgrave, SA Robertson, DF Callen, D Keefe

National Health and Medical Research Council of Australia Equipment Grant AUD
100,695
2006 A) ML866 PowerLab 4/30; B) MLI25/R Rat Tail NIBP system; C) MLTI25R Pulse Transducer/Pressure Cuff for NIBP System

Mackenzie L, DA Saint, J Ross, RJ Irvine, JA Owens, D Wilson,  J Schwartz, JL Morrison, SA Robertson, KL Kind, CT Roberts, DJ Kennaway

National Health and Medical Research Council of Australia Equipment Grant AUD
16,400
2005 FX-4000T Flexercell Tension Plus System Owens JA, and others National Health and Medical Research Council of Australia Equipment Grant AUD
33,000
2005 Genotyping and quantifying gene expression with the Applied Biosystems 7500 Real-time PCR System Owens JA and others National Health and Medical Research Council of Australia Equipment Grant AUD
40,000
2004

Clinical Chemistry Analyser

Owens JA and others

National Health and Medical Research Council of Australia Equipment Grant AUD
40,000
2000

Real-time quantitative DNA Amplification System

Owens, JA, McMillen, IC, Coulter CL, Gatford KL, Schwartz J, Saint DA et al

National Health and Medical Research Council of Australia Equipment Grant AUD
50,000
1997

Radiometer, Blood gases and co-oximetry analyser

Owens JA, Robinson JS, McMillen IC, Steele PNational Health and Medical Research Council of Australia Equipment Grant   AUD
41,000

Memberships

Date Role Membership Country
2013 - ongoing Member Womens and Child Health Research Institute Council Australia
2013 - ongoing Vice-President DOHAD ANZ Society Australia
2012 - ongoing Member National Health and Medical Research Council, Academy Australia
2012 - ongoing Member International Collaboration and Advisory Committee and General Assembly, EU
2008 - ongoing Co-Chair Women and Child Health Research Alliance Australia
2004 - 2006 Chair Australian and New Zealand Council for the Care of Animals in Research and Teaching (ANZCAART) Board and Council Australia
2003 - 2005 Member Australian Research Council College of Experts (Panel Chair in 2005) Australia
2002 - 2010 Member National Health and Medical Research Council Discipline and Program Grants Panels and Senior Fellowships Panel Australia
1992 - 1994 Director Australian Society for Medical Research Australia

Committee Memberships

Date Role Committee Institution Country
2012 - ongoing Member Joanna Briggs Institute Advisory Committee Joanna Briggs Institute Australia
2012 - ongoing Member Australian Research Centre for Population Oral Health (ARCPOH) Expert Advisory Committee Australian Research Centre for Population Oral Health (ARCPOH) Australia
2009 - ongoing Chair Faculty of Health Sciences Research Committee University of Adelaide Australia
2005 - ongoing Member University Research Committee University of Adelaide Australia
1997 - ongoing Member Faculty Health Sciences Research Committee (and Executive) University of Adelaide Australia

Board Memberships

Date Role Board name Institution name Country
2012 - ongoing Board Member Robinson Institute Board Robinson Institute, University of Adelaide Australia
2009 - ongoing Board Member Foundation Board of Advisors National Childhood Obesity Foundation (NCOF) United States
Position
Acting Deputy Vice-Chancellor (Research)
Phone
83135665
Campus
North Terrace
Building
Mitchell Building
Room Number
1 09
Org Unit
Division of Research and Innovation

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