Dr Joshua Schmidt
ARC Postdoctoral Associate
School of Biological Sciences
Faculty of Sciences
My research seeks to understand how Natural Selection and population history combine to shape genetic variation within and between populations. Currently I am developing statistical genetic and machine learning approaches to detect positive selection in diverse mammal and insect species. Previous and ongoing research projects include: local adaptation in chimpanzees; balancing selection in primates; population and quantitative genetics of pesticide resistance in drosophila.
My work uses theory and tools from population genetics, quantitative genetics and computational biology.
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Appointments
Date Position Institution name 2018 - 2019 Post-doctoral Researcher University College London 2014 - 2017 Post-doctoral Researcher Max Planck Institute for Evolutionary Anthropology -
Education
Date Institution name Country Title 2016 University of Melbourne Australia PhD -
Research Interests
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Journals
Year Citation 2020 Soto, D. C., Shew, C., Mastoras, M., Schmidt, J. M., Sahasrabudhe, R., Kaya, G., . . . Dennis, M. Y. (2020). Identification of Structural Variation in Chimpanzees Using Optical Mapping and Nanopore Sequencing.. Genes (Basel), 11(3), 20 pages.
WoS12020 Souilmi, Y., Tobler, R., Johar, A., Williams, M., Grey, S., Schmidt, J., . . . Cooper, A. (2020). Ancient human genomes reveal a hidden history of strong selection in Eurasia.
2019 Schmidt, J. M., de Manuel, M., Marques-Bonet, T., Castellano, S., & Andrés, A. M. (2019). The impact of genetic adaptation on chimpanzee subspecies differentiation. PLoS Genetics, 15(11), e1008485-1-e1008485-32.
WoS1 Europe PMC12018 Key, F., Abdul-Aziz, M., Mundry, R., Peter, B., Sekar, A., D Amato, M., . . . Andrés, A. (2018). Human local adaptation of the TRPM8 cold receptor along a latitudinal cline. PLoS Genetics, 14(5), e1007298-1-e1007298-22.
Scopus33 WoS31 Europe PMC142018 Bitarello, B. D., de Filippo, C., Teixeira, J. C., Schmidt, J. M., Kleinert, P., Meyer, D., & Andrés, A. M. (2018). Signatures of Long-Term Balancing Selection in Human Genomes. Genome Biology and Evolution, 10(3), 939-955.
Scopus23 WoS25 Europe PMC142018 Battlay, P., Leblanc, P., Green, L., Garud, N., Joshua, S., Fournier-Level, A., & Robin, C. (2018). Structural Variants and Selective Sweep Foci Contribute to Insecticide Resistance in the Drosophila Genetic Reference Panel. G3 : Genes, Genomes, Genetics, 8(11), 3489-3497.
Scopus9 WoS8 Europe PMC42018 Battlay, P., Leblanc, P., Green, L., Garud, N., Joshua, S., Fournier-Level, A., & Robin, C. (2018). Structural Variants and Selective Sweep Foci Contribute to Insecticide Resistance in the Drosophila Genetic Reference Panel. G3 : Genes, Genomes, Genetics, 8(11), 3489-3497.
Scopus9 WoS8 Europe PMC42017 Schmidt, J. M., Battlay, P., Gledhill-Smith, R. S., Good, R. T., Lumb, C., Fournier-Level, A., & Robin, C. (2017). Insights into DDT resistance from the Drosophila melanogaster Genetic Reference Panel. Genetics, 207(3), 1181-1193.
Scopus25 WoS19 Europe PMC102016 Battlay, P., Schmidt, J. M., Fournier-Level, A., & Robin, C. (2016). Genomic and transcriptomic associations identify a new insecticide resistance phenotype for the selective sweep at the Cyp6g1 locus of Drosophila melanogaster. G3 : Genes, Genomes, Genetics, 6(8), 2573-2581.
WoS21 Europe PMC142016 Fournier-Level, A., Neumann-Mondlak, A., Good, R. T., Green, L. M., Schmidt, J. M., & Robin, C. (2016). Behavioural response to combined insecticide and temperature stress in natural populations of Drosophila melanogaster.. Journal of evolutionary biology, 29(5), 1030-1044.
WoS9 Europe PMC42016 de Manuel, M., Kuhlwilm, M., Frandsen, P., Sousa, V. C., Desai, T., Prado-Martinez, J., . . . Marques-Bonet, T. (2016). Chimpanzee genomic diversity reveals ancient admixture with bonobos.. Science (New York, N.Y.), 354(6311), 477-481.
WoS89 Europe PMC542013 Remnant, E. J., Good, R. T., Schmidt, J. M., Lumb, C., Robin, C., Daborn, P. J., & Batterham, P. (2013). Gene duplication in the major insecticide target site, Rdl, in Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America, 110(36), 14705-14710.
WoS43 Europe PMC282011 Schmidt, J. M., & Robin, C. (2011). An Adaptive Allelic Series Featuring Complex Gene Rearrangements. PLOS GENETICS, 7(10), 2 pages.
WoS5 Europe PMC52010 Schmidt, J. M., Good, R. T., Appleton, B., Sherrard, J., Raymant, G. C., Bogwitz, M. R., . . . Robin, C. (2010). Copy Number Variation and Transposable Elements Feature in Recent, Ongoing Adaptation at the Cyp6g1 Locus. PLOS GENETICS, 6(6), 11 pages.
WoS160 Europe PMC123
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Current Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2020 Co-Supervisor Investigating the effects of fluctuating selection on patterns of genetic variation Doctor of Philosophy Doctorate Full Time Miss Olivia Lenore Johnson
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