Jonathan Ariyaratnam

Dr Jonathan Ariyaratnam

Research Fellow

School of Medicine

College of Health


Dr. Ariyaratnam is an academic cardiologist and electrophysiologist based at the University of Adelaide. Dr. Ariyaratnam completed his medical degree at the University of Cambridge, United Kingdom. He subsequently completed combined academic and clinical training in core medicine and cardiology as part of the prestigious NIHR clinical-academic training programme. He then completed subspecialty training and PhD in cardiac electrophysiology at the University of Adelaide and Royal Adelaide Hospital under the supervision of Professor Prash Sanders. Dr. Ariyaratnam's research encompasses all aspects of heart rhythm disorders and cardiac implantable devices. He has developed expertise in the relationship between atrial fibrillation and heart failure with preserved ejection fraction and is leading several studies investigating this. In addition, Dr. Ariyaratnam has co-led two randomised clinical trials investigating the management of atrial fibrillation, including the CS-ROOF RCT and the CAAN-AF RCT. Dr. Ariyaratnam has been awarded several national and international awards for his research including the Heart Rhythm Society Young Investigator Award (2024), the University of Adelaide Dean's Commendation for Doctoral Thesis Excellence (2024) the American Heart Association Samuel A. Levine Early Career Research Award (Finalist, 2022), the CSANZ Ralph Reader Clinical Science Prize (Finalist, 2022) and the Central Adelaide Local Health Network Nimmo Prize for Full-TIme Research (2022).

Date Position Institution name
2024 - ongoing Post-Doctoral Researcher University of Adelaide
2024 - ongoing Senior Cardiology EP and Devices Fellow Royal Adelaide Hospital

Date Type Title Institution Name Country Amount
2024 Award Heart Rhythm Society Young Investigator Award Heart Rhythm Society United States -
2024 Award Dean's Commendation for Doctoral Thesis Excellence University of Adelaide Australia -
2022 Award Samuel A. Levine Early Career Investigator Finalist American Heart Association United States -
2022 Award Nimmo Prize Central Adelaide Local Health Network Australia -
2022 Award Ralph Reader Clinical Science Prize Finalist Cardiac Society of Australia and New Zealand Australia -

Date Institution name Country Title
University of Cambridge United Kingdom MB BChir
University of Manchester United Kingdom MRes
University of Adelaide Australia PhD

Date Title Institution Country
2019 - 2023 Cardiac Electrophysiology and Devices Fellow Royal Adelaide Hospital Australia
2018 Senior Cardiology Registrar and Electrophysiology Fellow Health Education North West United Kingdom
2015 - 2018 Academic Clinical Fellow in Cardiology Health Education North West United Kingdom
2013 - 2015 Core Medical Trainee Oxford University Hospitals NHS Trust United Kingdom
2011 - 2013 Academic Foundation Trainee Health Education West Yorkshire United Kingdom

Date Title Institution name Country
2025 Certified Cardiac Electrophysiology Specilist - Adult International Board of Heart Rhythm Experts -
2024 Certificate of Completion of Training (Cardiology) Royal College of Physicians United Kingdom
MRCP Royal College of Physicians United Kingdom
Certified Cardiac Device Specialist The International Board of Heart Rhythm Experts United States

Year Citation
2025 Valappil, S. P., Chapman, D., Muenzinger, C., Puvrez, A., Ariyaratnam, J. P., Jayakumar, M., . . . Sanders, P. (2025). Left Bundle Area Pacing In Hypertrophied Hearts: An Ex-Vivo Ovine Model To Study Deployment Of Pacing Leads In Thick Septum. Heart Rhythm, 22(8), 2055-2064.
DOI
2025 Abbas, M., Emami, M., Kamsani, S. H., Ariyaratnam, J. P., Wilson, L., Stolcman, S., . . . Sanders, P. (2025). Pulsed Field Ablation for Atrial Fibrillation in Patients with Cardiac Implantable Electronic Devices. Heart Rhythm, 22(9), e594-e604.
DOI Scopus3 WoS3 Europe PMC1
2025 Howie, J. O., Dziano, J. K., Ariyaratnam, J. P., Abbas, M., Kenny, G. T., Evans, S., . . . Elliott, A. D. (2025). The Association of Age and Left Atrial Dysfunction in Patients with Atrial Fibrillation. Heart Rhythm, 22(12), 1-9.
DOI
2025 Sanders, P., Ariyaratnam, J. P., Puvrez, A., Middeldorp, M. E., Nicholls, S. J., Thomas, G., . . . Kalman, J. M. (2025). Cardiac Resynchronization Therapy And AV Node Ablation in Heart Failure with Reduced Ejection Fraction and Atrial Fibrillation. Rationale and Design of the CAAN-AF trial. Heart Rhythm O2, 6(11), 1-9.
DOI
2025 Dziano, J. K., Ariyaratnam, J. P., Middeldorp, M. E., Sanders, P., & Elliott, A. D. (2025). Obesity and Atrial Fibrillation: From Mechanisms to Treatment. Heart Lung and Circulation, 34(10), 1021-1032.
DOI Scopus1 WoS1
2025 Ariyaratnam, J. P., Elliott, A. D., Mishima, R. S., Dziano, J. K., Emami, M., Howie, J. O., . . . Sanders, P. (2025). Evaluating the Impact of Obesity and Epicardial Adiposity on the Presence of HFpEF in Patients With AF.. JACC Clin Electrophysiol, S2405-500X(25)00703-0.
DOI
2025 Saraf, K., Ariyaratnam, J. P., & Morris, G. M. (2025). A left-sided accessory pathway with bidirectional decremental conduction located at the aortomitral continuity. Heartrhythm Case Reports, 11(12), 1296-1302.
DOI
2025 Pathak, R. K., Elliott, A. D., Lau, D. H., Middeldorp, M. E., Linz, D., Fitzgerald, J. L., . . . Sanders, P. (2025). Aggressive Risk Factor Reduction Study for Atrial Fibrillation Implications for Ablation Outcomes: The ARREST-AF Randomized Clinical Trial.. JAMA Cardiol, 10(12), 1295-1304.
DOI Scopus2
2025 Ariyaratnam, J. P., Horsfall, G., Gall, S. A., Chu, G. S., Arujuna, A. V., & Chalil, S. (2025). The Impact of Prolonged Waiting List Times for Ablation of Atrial Fibrillation on Arrhythmia Recurrence Post-Ablation.. Heart Rhythm, S1547-5271(25)03038-3.
DOI
2025 Kakarla, S., Emami, M., Puvrez, A., Young, G. D., Ariyaratnam, J., Kamsani, S., . . . Sanders, P. (2025). Update on First-in-Human Experience of High-Energy ElectroPulse Pulsed Field Ablation.. Heart Rhythm, S1547-5271(25)03030-9.
DOI
2025 Kamsani, S. H., Fitzgerald, J. L., Thiyagarajah, A., Evans, S., Jayakumar, M., Ariyaratnam, J. P., . . . Lau, D. H. (2025). Adoption of left bundle branch area pacing using stylet-driven lead in a tertiary academic training center: Learning curve and acute procedural outcomes. Heart Rhythm O2, 6(3), 253-258.
DOI Europe PMC1
2024 Ariyaratnam, J. P., Mishima, R. S., McNamee, O., Emami, M., Thiyagarajah, A., Fitzgerald, J. L., . . . Elliott, A. D. (2024). Exercise echocardiography to assess left atrial function in patients with symptomatic AF. International Journal of Cardiology: Heart & Vasculature, 50, 101324-1-101324-7.
DOI Scopus5 WoS3 Europe PMC2
2024 Ariyaratnam, J. P., Elliott, A. D., Mishima, R. S., Kadhim, K., Emami, M., Fitzgerald, J. L., . . . Sanders, P. (2024). Structural, Functional, and Electrical Remodelling of the Atria with Reduced Cardiorespiratory Fitness: Implications for AF. JACC: Clinical Electrophysiology, 10(7.2), 1608-1619.
DOI Scopus5 WoS4 Europe PMC3
2024 Ariyaratnam, J. P., Middeldorp, M. E., Brooks, A. G., Thomas, G., Kadhim, K., Mahajan, R., . . . Sanders, P. (2024). Coronary Sinus Isolation for High Burden Atrial Fibrillation. A Randomized Clinical Trial. JACC: Clinical Electrophysiology, 11(1), 1-9.
DOI Scopus2 WoS2 Europe PMC3
2024 Shroff, J. P., Nair, A., Tuan, L. Q., Raja, D. C., Abhilash, S. P., Mehta, A., . . . Pathak, R. K. (2024). Electrocardiographic predictors of clinical outcomes in nonischemic cardiomyopathy patients with left bundle branch area pacing cardiac resynchronization therapy. Heart Rhythm, 22(6), 1523-1532.
DOI Scopus7 WoS7 Europe PMC5
2024 Shroff, J. P., Nair, A., Raja, D. C., Abhilash, S. P., Fiorese, S., Ariyaratnam, J., . . . Pathak, R. K. (2024). Comparison of Procedural Outcomes of Lumenless Fixed-Helix Versus Stylet-Driven Extendable-Helix Lead Systems in Left Bundle Branch Pacing: COMPARE LBBP.. Circulation. Arrhythmia and electrophysiology, 17(12), e013385.
DOI Scopus7 WoS6 Europe PMC4
2024 Ariyaratnam, J. P., Elliott, A. D., & Sanders, P. (2024). Reply: Subclinical Heart Failure With Preserved Ejection Fraction in Patients With Atrial Fibrillation.. JACC. Heart failure, 12(2), 423.
DOI Scopus1 WoS1 Europe PMC1
2024 Ariyaratnam, J. P., Mishima, R. S., Kadhim, K., Emami, M., Fitzgerald, J. L., Thiyagarajah, A., . . . Elliott, A. D. (2024). Utility and Validity of the HFA-PEFF and H2FPEF Scores in Patients With Symptomatic Atrial Fibrillation. JACC: Heart Failure, 12(6), 1015-1025.
DOI Scopus10 WoS8 Europe PMC6
2023 Elliott, A., Ariyaratnam, J., Howden, E. J., La Gerche, A., & Sanders, P. (2023). Influence of Exercise Training on the Left Atrium : Implications for Atrial Fibrillation, Heart Failure and Stroke. American Journal of Physiology: Heart and Circulatory Physiology, 325(4), H822-H836.
DOI Scopus20 WoS16 Europe PMC18
2023 Ariyaratnam, J. P., Elliott, A. D., Mishima, R. S., Kadhim, K., McNamee, O., Kuklik, P., . . . Sanders, P. (2023). Identification of Subclinical Heart Failure With Preserved Ejection Fraction in Patients With Symptomatic Atrial Fibrillation. JACC: Heart Failure, 11(11), 1626-1638.
DOI Scopus24 WoS23 Europe PMC13
2023 Pitman, B. M., Ariyaratnam, J., Williams, K., Evans, M., Reid-Smith, N., Wilson, L., . . . Lau, D. H. (2023). The Burden of Cardiac Implantable Electronic Device Checks in the Peri-MRI Setting: The CHECK-MRI Study.. Heart Lung and Circulation, 32(2), 252-260.
DOI Scopus3 WoS3 Europe PMC1
2022 Emami, M., Ariyaratnam, J. P., Pitman, B. M., & Lau, D. H. (2022). Tailored Cryoballoon Pulmonary Vein Ablation for Atrial Fibrillation: When to Stop the Freeze?. Heart, lung & circulation, 31(4), 457-459.
DOI
2022 Noubiap, J. J., Nyaga, U. F., Middeldorp, M. E., Fitzgerald, J. L., Ariyaratnam, J. P., Thomas, G., & Sanders, P. (2022). Frequency and prognostic significance of atrial fibrillation in acute pulmonary embolism: A pooled analysis. Respiratory Medicine, 199, 1-7.
DOI Scopus10 WoS7 Europe PMC5
2022 Mishima, R. S., Ariyaratnam, J. P., Pitman, B. M., Malik, V., Emami, M., McNamee, O., . . . Elliott, A. D. (2022). Cardiorespiratory fitness, obesity and left atrial function in patients with atrial fibrillation. International Journal of Cardiology: Heart & Vasculature, 42, 101083-1-101083-8.
DOI Scopus11 WoS11 Europe PMC11
2022 Ariyaratnam, J. P., Sanders, P., & Elliott, A. D. (2022). Atrial Fibrillation Ablation in Patients with Heart Failure with Preserved Ejection Fraction: Complexities in Diagnosis and Treatment. Heart Rhythm O2, 3(5), 509-510.
DOI Scopus1 WoS1
2022 Middeldorp, M. E., Ariyaratnam, J. P., Kamsani, S. H., Albert, C. M., & Sanders, P. (2022). Hypertension and atrial fibrillation.. Journal of hypertension, 40(12), 2337-2352.
DOI Scopus15 WoS18 Europe PMC16
2021 Mishima, R. S., Verdicchio, C. V., Noubiap, J. J., Ariyaratnam, J. P., Gallagher, C., Jones, D., . . . Elliott, A. D. (2021). Self-reported Physical Activity and Atrial Fibrillation Risk: A Systematic Review and Meta-analysis. Heart Rhythm, 18(4), 520-528.
DOI Scopus34 WoS33 Europe PMC30
2021 Ariyaratnam, J. P., Lau, D. H., Sanders, P., & Kalman, J. M. (2021). Atrial Fibrillation and Heart Failure: Epidemiology, Pathophysiology, Prognosis, and Management. Cardiac Electrophysiology Clinics, 13(1), 47-62.
DOI Scopus34 Europe PMC26
2021 Boyett, M. R., Yanni, J., Tellez, J., Bucchi, A., Mesirca, P., Cai, X., . . . D'Souza, A. (2021). Regulation of sinus node pacemaking and atrioventricular node conduction by HCN channels in health and disease. Progress in Biophysics and Molecular Biology, 166, 61-85.
DOI Scopus24 WoS20 Europe PMC20
2021 Ariyaratnam, J. P., Elliott, A. D., Mishima, R. S., Gallagher, C., Lau, D. H., & Sanders, P. (2021). Heart failure with preserved ejection fraction: An alternative paradigm to explain the clinical implications of atrial fibrillation. Heart Rhythm O2, 2(6), 771-783.
DOI Scopus35 WoS32 Europe PMC25
2021 Ariyaratnam, J. P., Stokes, M. B., & Lau, D. H. (2021). Implantable cardioverter-defibrillator in patients awaiting heart transplantation: Reinforcing the bridge to transplant. Heart Rhythm O2, 2(6), 719-720.
DOI Scopus1 WoS1
2020 Middeldorp, M. E., Ariyaratnam, J., Lau, D., & Sanders, P. (2020). Lifestyle modifications for treatment of atrial fibrillation. Heart, 106(5), 325-332.
DOI Scopus95 WoS86 Europe PMC77
2020 Ariyaratnam, J. P., Middeldorp, M., Thomas, G., Noubiap Nzeale, J. J. N., Lau, D., & Sanders, P. (2020). Risk factor management before and after atrial fibrillation ablation. Cardiac Electrophysiology Clinics, 12(2), 141-154.
DOI Scopus8 Europe PMC7
2020 Ariyaratnam, J. P., & Sanders, P. (2020). Protecting the Oesophagus During Left Atrial Ablation: A Surplus of Options but an Absence of Evidence.. Indian Pacing Electrophysiol J, 20(6), 219-220.
DOI Scopus1
2020 Yanni, J., D'Souza, A., Wang, Y., Li, N., Hansen, B. J., Zakharkin, S. O., . . . Boyett, M. R. (2020). Silencing miR-370-3p rescues funny current and sinus node function in heart failure.. Scientific reports, 10(1), 11279.
DOI Scopus40 WoS37 Europe PMC33
2020 Katsaras, D., Ariyaratnam, J., Chalil, S., & Abozguia, K. (2020). An unusual response of pulmonary vein bigeminy to antral ablation.. Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 59(3), 619-621.
DOI
2019 Virk, S. A., Ariyaratnam, J., Bennett, R. G., & Kumar, S. (2019). Updated systematic review and meta-analysis of the impact of contact force sensing on the safety and efficacy of atrial fibrillation ablation: Discrepancy between observational studies and randomized control trial data. Europace, 21(2), 239-249.
DOI Scopus34 WoS31 Europe PMC27
2019 Morris, G. M., & Ariyaratnam, J. P. (2019). Embryology of the Cardiac Conduction System Relevant to Arrhythmias. Cardiac Electrophysiology Clinics, 11(3), 409-420.
DOI Scopus7 Europe PMC2
2017 Boyett, M. R., Wang, Y., Nakao, S., Ariyaratnam, J., Hart, G., Monfredi, O., & D’Souza, A. (2017). Point: Exercise training-induced bradycardia is caused by changes in intrinsic sinus node function. Journal of Applied Physiology, 123(3), 684-685.
DOI Scopus26 WoS26 Europe PMC16
2017 Boyett, M. R., Wang, Y., Nakao, S., Ariyaratnam, J., Hart, G., Monfredi, O., & D’Souza, A. (2017). Rebuttal from Boyett et al.. Journal of Applied Physiology, 123(3), 689.
DOI Scopus3 WoS2 Europe PMC2
2014 Ariyaratnam, J., & Subramanian, V. (2014). Association between thiopurine use and nonmelanoma skin cancers in patients with inflammatory bowel disease: A meta-analysis. American Journal of Gastroenterology, 109(2), 163-169.
DOI Scopus155 WoS130 Europe PMC117

Year Citation
2024 Shahmohamadi, E., Middeldorp, M., Ariyaratnam, J., Jayakumar, M., Fitzgerald, J., Elliott, A., & Sanders, P. (2024). Ethnic differences in Body Mass Index Cut-off Values Associated with Cardiovascular Risks in South Asians Compared to White Population: A Systematic Review and Meta-analysis. In CIRCULATION Vol. 150 (pp. 3 pages). IL, Chicago: LIPPINCOTT WILLIAMS & WILKINS.
DOI
2024 Dziano, J., Howie, J., Ariyaratnam, J., Middeldorp, M., Emami, M., Mishima, R., . . . Elliott, A. (2024). Abnormalities in Cardiopulmonary Exercise Test Associated With More Advance Atrial Cardiomyopathy. In Heart Lung and Circulation Vol. 33 (pp. S146-S147). Elsevier BV.
DOI
2024 Abbas, M., Ariyaratnam, J., Dziano, J., Howie, J., Fitzgerald, J., Jayakumar, M., . . . Sanders, P. (2024). Implications of Rate Limiting Medications in Patients with Atrial Fibrillation and Heart Failure with Preserved Ejection Fraction. In CIRCULATION Vol. 150 (pp. 2 pages). IL, Chicago: LIPPINCOTT WILLIAMS & WILKINS.
DOI
2021 Ariyaratnam, J. P., Mishima, R., Gallagher, C., Emami, M., Wong, C., Malik, V., . . . Sanders, P. (2021). Left Atrial Hemodynamics and Invasive Functional Testing to Characterize Heart Failure With Preserved Ejection Fraction in Patients With Atrial Fibrillation. In CIRCULATION Vol. 144 (pp. 3 pages). Boston, MA: LIPPINCOTT WILLIAMS & WILKINS.

Date Role Research Topic Program Degree Type Student Load Student Name
2025 Co-Supervisor Surgical technologies in ablation of atrial fibrillation Master of Philosophy (Surgery) Master Full Time Dr Chris Robins
2025 Co-Supervisor Mapping Beyond Pulmonary Veins: A Comparative Lesional Analysis of Focal and Multipolar Pulsed-field Ablation Systems. Master of Philosophy (Clinical Science) Master Full Time Dr Sai Kiran Kakarla
2025 Co-Supervisor The role of continuous remote monitoring in patients with cardiac implantable electronic devices Doctor of Philosophy Doctorate Full Time Dr Mohamed Abdelmonim Abdelkarim Abbas
2025 Co-Supervisor Mapping Beyond Pulmonary Veins: A Comparative Lesional Analysis of Focal and Multipolar Pulsed-field Ablation Systems. - Master Full Time Dr Sai Kiran Kakarla
2025 Co-Supervisor The role of continuous remote monitoring in patients with cardiac implantable electronic devices Doctor of Philosophy Doctorate Full Time Dr Mohamed Abdelmonim Abdelkarim Abbas
2025 Co-Supervisor Surgical technologies in ablation of atrial fibrillation Master of Research Master Full Time Dr Chris Robins
2024 Co-Supervisor Redesigning care with an Emergency Department protocol and rapid access clinic to reduce hospitalisations for Atrial Fibrillation (REDUCE-AF) Master of Philosophy (Clinical Science) Master Full Time Dr Alessandra Pina
2024 Co-Supervisor Left atrial compliance and exercise tolerance in atrial fibrillation Master of Philosophy (Medical Science) Master Full Time Dr Sanjai Pattu Valappil
2024 Co-Supervisor Left atrial compliance and exercise tolerance in atrial fibrillation - Master Full Time Dr Sanjai Pattu Valappil
2024 Co-Supervisor The role of continuous remote monitoring in patients with cardiac implantable electronic devices - Master Full Time Dr Mohamed Abdelmonim Abdelkarim Abbas
2024 Co-Supervisor Redesigning care with an Emergency Department protocol and rapid access clinic to reduce hospitalisations for Atrial Fibrillation (REDUCE-AF) - Master Full Time Dr Alessandra Pina

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